Publications by authors named "Enrique Lastra"

17Publications

A PALB2 truncating mutation: Implication in cancer prevention and therapy of Hereditary Breast and Ovarian Cancer.

Breast 2019 Feb 29;43:91-96. Epub 2018 Nov 29.

Cancer Genetics Group, Institute of Genetics and Molecular Biology (UVa-CSIC), Sanz y Forés 3, 47003 Valladolid, Spain. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S09609776183032
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http://dx.doi.org/10.1016/j.breast.2018.11.010DOI Listing
February 2019

Unraveling the molecular effect of a rare missense mutation in BRIP1 associated with inherited breast cancer.

Mol Carcinog 2019 01 22;58(1):156-160. Epub 2018 Sep 22.

Cancer Genetics Group, Institute of Genetics and Molecular Biology (UVa-CSIC), Valladolid, Spain.

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http://dx.doi.org/10.1002/mc.22910DOI Listing
January 2019

Genetic dissection of the BRCA2 promoter and transcriptional impact of DNA variants.

Breast Cancer Res Treat 2018 Aug 15;171(1):53-63. Epub 2018 May 15.

Grupo de Splicing y Cáncer, Instituto de Biología y Genética Molecular (IBGM), Consejo Superior de Investigaciones Científicas (CSIC-UVa), Sanz y Forés 3, 47003, Valladolid, Spain.

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http://dx.doi.org/10.1007/s10549-018-4826-7DOI Listing
August 2018

Genotype-phenotype correlation in MMR mutation-positive families with Lynch syndrome.

Int J Colorectal Dis 2013 Sep 16;28(9):1195-201. Epub 2013 Apr 16.

Instituto de Biología y Genética Molecular, IBGM-UVA-CSIC, Valladolid, Spain.

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http://dx.doi.org/10.1007/s00384-013-1685-xDOI Listing
September 2013

Evaluating the effect of unclassified variants identified in MMR genes using phenotypic features, bioinformatics prediction, and RNA assays.

J Mol Diagn 2013 May 20;15(3):380-90. Epub 2013 Mar 20.

Cancer Genetics Laboratory, Institute of Biology and Molecular Genetics, University of Valladolid, Valladolid, Spain.

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http://dx.doi.org/10.1016/j.jmoldx.2013.02.003DOI Listing
May 2013

SEOM clinical guidelines for hereditary cancer.

Clin Transl Oncol 2011 Aug;13(8):580-6

High Risk and Cancer Prevention Unit, Medical Oncology Department, Vall d'Hebron Institute of Oncology (VHIO), Barcelona, Spain.

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http://dx.doi.org/10.1007/s12094-011-0701-2DOI Listing
August 2011

KRAS, BRAF, EGFR and HER2 gene status in a Spanish population of colorectal cancer.

Mol Biol Rep 2011 Feb 20;38(2):1315-20. Epub 2010 Jun 20.

Unidad de Investigación, Hospital General Yagüe, Avenida del Cid 96, 09005, Burgos, Spain.

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http://dx.doi.org/10.1007/s11033-010-0232-xDOI Listing
February 2011

A high proportion of DNA variants of BRCA1 and BRCA2 is associated with aberrant splicing in breast/ovarian cancer patients.

Clin Cancer Res 2010 Mar 9;16(6):1957-67. Epub 2010 Mar 9.

Grupo de Genetica del Cancer, Instituto de Biologia y Genetica Molecular, Consejo Superior de Investigaciones Cientificas-Universidad de Valladolid, Valladolid, Spain.

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http://clincancerres.aacrjournals.org/cgi/doi/10.1158/1078-0
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http://dx.doi.org/10.1158/1078-0432.CCR-09-2564DOI Listing
March 2010

Two founder BRCA2 mutations predispose to breast cancer in young women.

Breast Cancer Res Treat 2010 Jul 1;122(2):567-71. Epub 2009 Dec 1.

Genética del Cáncer, Instituto de Biología y Genética Molecular (UVa-CSIC), Sanz y Forés s/n, 47003, Valladolid, Spain.

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http://dx.doi.org/10.1007/s10549-009-0661-1DOI Listing
July 2010

A new strategy to screen MMR genes in Lynch Syndrome: HA-CAE, MLPA and RT-PCR.

Eur J Cancer 2009 May 26;45(8):1485-93. Epub 2009 Feb 26.

Laboratorio Cáncer Hereditario, IBGM-CSIC, Universidad de Valladolid, C/ Sanz y Forés s/n, 47003 Valladolid, Spain.

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http://dx.doi.org/10.1016/j.ejca.2009.01.030DOI Listing
May 2009

Rapid mutation detection in complex genes by heteroduplex analysis with capillary array electrophoresis.

Electrophoresis 2005 Jun;26(13):2539-52

Laboratorio de Genética del Cáncer, Instituto de Biología y Genética Molecular, Facultad de Medicina, Universidad de Valladolid, Valladolid, Spain.

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http://doi.wiley.com/10.1002/elps.200410425
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http://dx.doi.org/10.1002/elps.200410425DOI Listing
June 2005