Enrico Mini

Enrico Mini

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Publications by authors named "Enrico Mini"

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A potential novel drug combination for adjuvant therapy in lung cancer: reflections on an early phase of clinical development.

J Chemother 2019 Oct 21;31(6):295-296. Epub 2019 Aug 21.

Department of Health Sciences, University of Florence , Firenze , Italy.

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http://dx.doi.org/10.1080/1120009X.2019.1651014DOI Listing
October 2019

Role of ATP-binding cassette transporters in cancer initiation and progression.

Semin Cancer Biol 2019 Aug 11. Epub 2019 Aug 11.

Department of Health Sciences, University of Florence, Florence, Italy.

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http://dx.doi.org/10.1016/j.semcancer.2019.08.006DOI Listing
August 2019

Results from a meta-analysis of immune checkpoint inhibitors in first-line renal cancer patients: does PD-L1 matter?

Ther Adv Med Oncol 2019 5;11:1758835919861905. Epub 2019 Aug 5.

Department of Health Sciences, University of Florence, Italy.

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http://dx.doi.org/10.1177/1758835919861905DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6683319PMC
August 2019

Novel Agents in Heavily Pretreated Metastatic Gastric Cancer: More Shadows Than Lights.

J Oncol 2019 4;2019:5692317. Epub 2019 Jul 4.

Department of Health Sciences, University of Florence, Viale Pieraccini 6, 50139 Florence, Italy.

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http://dx.doi.org/10.1155/2019/5692317DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6637676PMC
July 2019

Analysis of Prognostic Factors for Resected Synchronous and Metachronous Liver Metastases from Colorectal Cancer.

Gastroenterol Res Pract 2018 11;2018:5353727. Epub 2018 Jul 11.

Department of Surgery and Translational Medicine, University of Florence, AOU Careggi, Largo Brambilla 3, 50134 Florence, Italy.

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http://dx.doi.org/10.1155/2018/5353727DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6079496PMC
July 2018

ERRATUM.

Oncol Res 2018 Mar;26(2):333-334

Department of Health Sciences, University of Florence, Florence, Italy.

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http://dx.doi.org/10.3727/096504018X15187172557369DOI Listing
March 2018

Prognostic Value of BRAF and KRAS Mutations in MSI and MSS Stage III Colon Cancer.

J Natl Cancer Inst 2017 05 31;109(5). Epub 2016 Dec 31.

Affiliations of authors: Department of Gastroenterology and GI Oncology, Université Paris Descartes, Hopital Européen Georges Pompidou, Paris, France (JTai); Fédération Francophone de Cancérologie Digestive (FFCD), Dijon, France (KLM); Alliance Statistics and Data Center, Mayo Clinic, Rochester, MN (QS, DJS); Department of Pathology, Centre Jean Perrin, EA ERTICa, Université d'Auvergne, Clermont-Ferrand, France (FPL); Centre Hospitalier Universitaire Robert Debré, Reims, France (OB); Medical Oncology Department, Vall d'Hebron University Hospital and Institute of Oncology (VHIO), Barcelona, Spain (JTab); Spanish Gastrointestinal Tumors TTD Group, Universitat Autònoma de Barcelona, Barcelona, Spain (JTab); Section of Clinical Pharmacology and Oncology, Department of Health Sciences, University of Florence, Florence, Italy (EM); Division of Medical Oncology, Ohio State University Comprehensive Cancer Center, Columbus, OH (RMG); First Medical Department, University Hospital Carl Gustav Carus, Dresden, Germany (GF); Department of Gastroenterology, Hôpital Universitaire Erasme, Brussels, Belgium (JLVL); Department of Oncology, Mayo Clinic and Mayo Cancer Center, Rochester, MN (SRA, FAS); Pathology Department, Ambroise Paré Hospital, Boulogne, France (JFE); Université Paris Descartes, Sorbonne Paris Cité, France (PLP); Assistance Publique Hôpitaux de Paris, Department of Biology, Hôpital Européen Georges Pompidou, Paris, France (PLP); INSERM UMR-S1147, Paris, France (PLP).

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http://dx.doi.org/10.1093/jnci/djw272DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6075212PMC
May 2017

Enhanced Efficacy of Artemisinin Loaded in Transferrin-Conjugated Liposomes versus Stealth Liposomes against HCT-8 Colon Cancer Cells.

ChemMedChem 2016 08 21;11(16):1745-51. Epub 2016 Mar 21.

Department of Chemistry, University of Florence, via U. Schiff 6, 50019, Sesto Fiorentino, Florence, Italy.

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http://dx.doi.org/10.1002/cmdc.201500586DOI Listing
August 2016

Prognostic Effect of BRAF and KRAS Mutations in Patients With Stage III Colon Cancer Treated With Leucovorin, Fluorouracil, and Oxaliplatin With or Without Cetuximab: A Post Hoc Analysis of the PETACC-8 Trial.

JAMA Oncol 2016 May;2(5):643-653

Centre de Recherché UMR-S 1147, Médecine Personnalisée, Pharmacogénomique, Optimisation Thérapeutique, Institut National de la Santé et de la Recherche Médicale, Paris, France6Paris Descartes University, Department of Biology, European Georges Pompidou Ho.

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http://dx.doi.org/10.1001/jamaoncol.2015.5225DOI Listing
May 2016

Effect of the SOD mimetic MnL4 on in vitro and in vivo oxaliplatin toxicity: Possible aid in chemotherapy induced neuropathy.

Free Radic Biol Med 2016 Apr 28;93:67-76. Epub 2016 Jan 28.

Dipartimento di Neuroscienze, Psicologia, Scienze del Farmaco e Salute del Bambino (NEUROFARBA), Sezione di Farmacologia e Tossicologia, Università degli Studi di Firenze, Viale Pieraccini, 6, Firenze 50139, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.freeradbiomed.2016.01.023DOI Listing
April 2016

Cytotoxic properties of a new organometallic platinum(II) complex and its gold(I) heterobimetallic derivatives.

Dalton Trans 2016 Jan;45(2):579-90

Department of Chemistry and Pharmacy, University of Sassari, via Vienna 2, 07100 Sassari, Italy. and CIRCC, Consorzio Interuniversitario Reattività Chimica e Catalisi, Università di Bari, Via Celso Ulpiani 27, 70126 Bari, Italy.

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http://dx.doi.org/10.1039/c5dt02714dDOI Listing
January 2016

Clinical validity of a DPYD-based pharmacogenetic test to predict severe toxicity to fluoropyrimidines.

Int J Cancer 2015 Dec 14;137(12):2971-80. Epub 2015 Jul 14.

Experimental and Clinical Pharmacology, Centro Di Riferimento Oncologico-National Cancer Institute, 2-33081, Aviano, Italy.

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http://dx.doi.org/10.1002/ijc.29654DOI Listing
December 2015

In vitro study on the safety of near infrared laser therapy in its potential application as postmastectomy lymphedema treatment.

J Photochem Photobiol B 2015 Oct 11;151:285-96. Epub 2015 Aug 11.

ASAcampus Joint Laboratory, ASA Research Division, Department of Experimental and Clinical Biomedical Sciences "Mario Serio", University of Florence, Viale Pieraccini 6, I-50139 Florence, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.jphotobiol.2015.08.003DOI Listing
October 2015

Emerging drugs in refractory colorectal cancer.

Future Med Chem 2015 Aug 21;7(12):1491-501. Epub 2015 Aug 21.

Department of Experimental & Clinical Medicine, University of Florence, viale Pieraccini, 6 - 50139 Florence, Italy.

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http://dx.doi.org/10.4155/fmc.15.85DOI Listing
August 2015

In vitro assessment of antibody-conjugated gold nanorods for systemic injections.

J Nanobiotechnology 2014 Dec 5;12:55. Epub 2014 Dec 5.

Istituto di Fisica Applicata 'Nello Carrara', Consiglio Nazionale delle Ricerche, Via Madonna del Piano 10, 50019, Sesto Fiorentino, Italy.

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http://dx.doi.org/10.1186/s12951-014-0055-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4266900PMC
December 2014

Multidrug resistance (MDR) reversers: High activity and efficacy in a series of asymmetrical N,N-bis(alkanol)amine aryl esters.

Eur J Med Chem 2014 Nov 30;87:398-412. Epub 2014 Sep 30.

Dipartimento NEUROFARBA-Sezione di Farmaceutica e Nutraceutica, Università di Firenze, Via Ugo Schiff 6, 50019 Sesto Fiorentino, FI, Italy.

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http://dx.doi.org/10.1016/j.ejmech.2014.09.084DOI Listing
November 2014

Strategy to provide a useful solution to effective delivery of dihydroartemisinin: development, characterization and in vitro studies of liposomal formulations.

Colloids Surf B Biointerfaces 2014 Apr 6;116:121-7. Epub 2014 Jan 6.

Department of Chemistry, University of Florence, via U. Schiff 6, 50019 Sesto Fiorentino, Florence Italy.

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http://dx.doi.org/10.1016/j.colsurfb.2013.12.019DOI Listing
April 2014

Chemistry and biology of two novel gold(I) carbene complexes as prospective anticancer agents.

Inorg Chem 2014 Mar 18;53(5):2396-403. Epub 2014 Feb 18.

Laboratory of Metals in Medicine, Department of Chemistry, University of Florence , via della Lastruccia 3, 50019 Sesto Fiorentino, Florence, Italy.

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http://dx.doi.org/10.1021/ic401731aDOI Listing
March 2014

Gemcitabine, oxaliplatin, levofolinate, 5-fluorouracil, granulocyte-macrophage colony-stimulating factor, and interleukin-2 (GOLFIG) versus FOLFOX chemotherapy in metastatic colorectal cancer patients: the GOLFIG-2 multicentric open-label randomized phase III trial.

J Immunother 2014 Jan;37(1):26-35

*Radiotherapy Unit §Medical Oncology Unit, Department of Oncology, Microbiology Section ∥Department of Biotechnology ¶Rheumatology Unit, Department of Medicine #Pharmacy Unit, Siena University Hospital "Santa Maria alle Scotte", Istituto Toscano Tumory, Siena †Medical Oncology Unit ‡Department of Legal, Historical, Economic and Social Sciences-DSGSES, Magna Graecia University of Catanzaro ††Translational Medical Oncology Unit, "Magna Graecia" University and "Tommaso Campanella" Cancer Center, Campus "Salvatore Venuta," Catanzaro **Department of Biochemistry, Biophysics and General Pathology, Second University of Naples, Naples ‡‡Chemotherapy Unit, Department of Oncology, Florence University School of Medicine, Florence §§Medical Oncology Unit, Department of Oncology, Cagliari University School of Medicine, Cagliari ∥∥Medical Oncology Unit, Centro Oncologico Romagnolo, Forlì, Italy.

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http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:land
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http://dx.doi.org/10.1097/CJI.0000000000000004DOI Listing
January 2014

The molecular mechanisms of antimetastatic ruthenium compounds explored through DIGE proteomics.

J Inorg Biochem 2013 Jan 14;118:94-9. Epub 2012 Oct 14.

Department of Biochemical Sciences, University of Florence, viale G. Morgagni, 50, 50134 Firenze, Italy.

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http://linkinghub.elsevier.com/retrieve/pii/S016201341200322
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http://dx.doi.org/10.1016/j.jinorgbio.2012.10.003DOI Listing
January 2013

Overcoming tumor multidrug resistance using drugs able to evade P-glycoprotein or to exploit its expression.

Med Res Rev 2012 Nov 3;32(6):1220-62. Epub 2011 Mar 3.

Department of Preclinical and Clinical Pharmacology, University of Florence Florence, Italy, Viale Pieraccini, 6-50139, Firenze, Italy.

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http://dx.doi.org/10.1002/med.20239DOI Listing
November 2012

2D-DIGE analysis of ovarian cancer cell responses to cytotoxic gold compounds.

Mol Biosyst 2012 Apr 2;8(4):985-93. Epub 2011 Dec 2.

Department of Chemistry, University of Florence, via della Lastruccia 3, 50019 Sesto Fiorentino, Italy.

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http://dx.doi.org/10.1039/c1mb05386hDOI Listing
April 2012

Proteomic analysis of ovarian cancer cell responses to cytotoxic gold compounds.

Metallomics 2012 Mar 10;4(3):307-14. Epub 2012 Feb 10.

Department of Biochemical Sciences, University of Florence, viale G. Morgagni, 50, 50134 Firenze, Italy.

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http://dx.doi.org/10.1039/c2mt00083kDOI Listing
March 2012

Epigenetics and chemoresistance in colorectal cancer: an opportunity for treatment tailoring and novel therapeutic strategies.

Drug Resist Updat 2011 Dec 28;14(6):280-96. Epub 2011 Sep 28.

Division of Pharmacology, Department of Internal Medicine, University of Pisa, Pisa, Italy.

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http://dx.doi.org/10.1016/j.drup.2011.08.001DOI Listing
December 2011

Genomic and genetic alterations influence the progression of gastric cancer.

World J Gastroenterol 2011 Jan;17(3):290-9

Department of Preclinical and Clinical Pharmacology, University of Florence, Florence 50139, Italy.

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http://dx.doi.org/10.3748/wjg.v17.i3.290DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3022288PMC
January 2011

Gold compounds as anticancer agents: chemistry, cellular pharmacology, and preclinical studies.

Med Res Rev 2010 May;30(3):550-80

Department of Preclinical and Clinical Pharmacology, University of Florence, viale Pieraccini 6, 50139 Florence, Italy.

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http://dx.doi.org/10.1002/med.20168DOI Listing
May 2010

Exploring the biochemical mechanisms of cytotoxic gold compounds: a proteomic study.

J Biol Inorg Chem 2010 May 29;15(4):573-82. Epub 2010 Jan 29.

Department of Biochemical Sciences, University of Florence, Viale G. Morgagni, 50, 50134, Florence, Italy.

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http://dx.doi.org/10.1007/s00775-010-0624-3DOI Listing
May 2010

Structure-activity relationships studies in a series of N,N-bis(alkanol)amine aryl esters as P-glycoprotein (Pgp) dependent multidrug resistance (MDR) inhibitors.

J Med Chem 2010 Feb;53(4):1755-62

Dipartimento di Scienze Farmaceutiche, Laboratorio di Progettazione Sintesi e Studio di Eterocicli Bioattivi (HeteroBioLab), Università di Firenze, via Ugo Schiff 6, 50019 Sesto Fiorentino (FI), Italy.

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http://dx.doi.org/10.1021/jm9016174DOI Listing
February 2010

Natural compounds for cancer treatment and prevention.

Pharmacol Res 2009 Jun 7;59(6):365-78. Epub 2009 Feb 7.

Department of Pharmacology, University of Florence, Florence, Italy.

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http://dx.doi.org/10.1016/j.phrs.2009.01.017DOI Listing
June 2009

Pharmacogenetics: implementing personalized medicine.

Clin Cases Miner Bone Metab 2009 Jan;6(1):17-24

Department of Pharmacology, University of Florence, Florence, Italy.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2781211PMC
January 2009

Synthesis of new pyrazolo[5,1-c][1,2,4] benzotriazines, pyrazolo[5,1-c]pyrido[4,3-e][1,2,4] triazines and their open analogues as cytotoxic agents in normoxic and hypoxic conditions.

Bioorg Med Chem 2008 Nov 26;16(21):9409-19. Epub 2008 Sep 26.

Dipartimento di Scienze Farmaceutiche, Università degli Studi di Firenze, Via U. Schiff 6, 50019 Polo Scientifico, Sesto Fiorentino, Firenze, Italy.

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http://dx.doi.org/10.1016/j.bmc.2008.09.055DOI Listing
November 2008

Gold(III) compounds as anticancer agents: relevance of gold-protein interactions for their mechanism of action.

J Inorg Biochem 2008 Mar 28;102(3):564-75. Epub 2007 Nov 28.

Department of Chemistry, University of Florence, Via della Lastruccia 3, 50019 Sesto Fiorentino, Florence, Italy.

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http://linkinghub.elsevier.com/retrieve/pii/S016201340700306
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http://dx.doi.org/10.1016/j.jinorgbio.2007.11.003DOI Listing
March 2008

Mechanisms of cytotoxicity of selected organogold(III) compounds.

J Med Chem 2005 Oct;48(21):6761-5

Department of Pharmacology and Chemistry, University of Florence, Florence, Italy, Department of Chemistry, University of Sassari, Sassari, Italy.

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http://dx.doi.org/10.1021/jm050493oDOI Listing
October 2005

In vitro antiproliferative activity against human colon cancer cell lines of representative 4-thiazolidinones. Part I.

Bioorg Med Chem Lett 2005 Sep;15(17):3930-3

Dipartimento Farmaco-chimico, Università di Messina,Viale SS. Annunziata, 98168 Messina, Italy.

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http://dx.doi.org/10.1016/j.bmcl.2005.05.093DOI Listing
September 2005

Solution chemistry and cytotoxic properties of novel organogold(III) compounds.

Bioorg Med Chem 2004 Dec;12(23):6039-43

Department of Chemistry, University of Florence, Via della Lastruccia 3, 50019 Sesto Fiorentino, Florence, Italy.

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http://dx.doi.org/10.1016/j.bmc.2004.09.014DOI Listing
December 2004

Effect of methylenetetrahydrofolate reductase 677C-->T polymorphism on toxicity and homocysteine plasma level after chronic methotrexate treatment of ovarian cancer patients.

Int J Cancer 2003 Jan;103(3):294-9

Experimental and Clinical Pharmacology Unit, Centro di Riferimento Oncologico, National Cancer Institute, Aviano, Italy.

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http://dx.doi.org/10.1002/ijc.10847DOI Listing
January 2003

Limited sampling model for the analysis of 5-fluorouracil pharmacokinetics in adjuvant chemotherapy for colorectal cancer.

Clin Pharmacol Ther 2002 Dec;72(6):627-37

Division of Pharmacology and Chemotherapy, Department of Oncology, Transplants and Advanced Technologies in Medicine, University of Pisa, Italy.

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http://dx.doi.org/10.1067/mcp.2002.128867DOI Listing
December 2002

Clinical pharmacokinetics of depot leuprorelin.

Clin Pharmacokinet 2002 ;41(7):485-504

Department of Preclinical and Clinical Pharmacology, Università di Firenze, Via XX Settembre 104, 50129 Florence, Italy.

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http://dx.doi.org/10.2165/00003088-200241070-00003DOI Listing
August 2002