Publications by authors named "Enrico Millo"

69Publications

New Insights into the Binding Features of F508del CFTR Potentiators: A Molecular Docking, Pharmacophore Mapping and QSAR Analysis Approach.

Pharmaceuticals (Basel) 2020 Dec 4;13(12). Epub 2020 Dec 4.

Department of Pharmacy, Section of Medicinal Chemistry, School of Medical and Pharmaceutical Sciences, University of Genoa, Viale Benedetto XV 3, 16132 Genoa, Italy.

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December 2020

Molecular Docking and QSAR Studies as Computational Tools Exploring the Rescue Ability of F508del CFTR Correctors.

Int J Mol Sci 2020 Oct 29;21(21). Epub 2020 Oct 29.

Department of Pharmacy, Section of Medicinal Chemistry, School of Medical and Pharmaceutical Sciences, University of Genoa, Viale Benedetto XV, 3, 16132 Genoa, Italy.

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October 2020

Discovery of novel VX-809 hybrid derivatives as F508del-CFTR correctors by molecular modeling, chemical synthesis and biological assays.

Eur J Med Chem 2020 Dec 12;208:112833. Epub 2020 Sep 12.

Department of Experimental Medicine, Section of Biochemistry, University of Genoa, Viale Benedetto XV 1, 16132, Genoa, Italy; Center of Excellence for Biomedical Research (CEBR), University of Genoa, Viale Benedetto XV 9, 16132, Genoa, Italy. Electronic address:

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December 2020

Synthesis and structure-activity relationship of aminoarylthiazole derivatives as potential potentiators of the chloride transport defect in cystic fibrosis.

Med Chem 2020 Mar 5. Epub 2020 Mar 5.

University of Genoa, Experimental Medicine, Section of Biochemistry and Center of Excellence for Biomedical Research (CEBR), Viale Benedetto XV 1. Italy.

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March 2020

Differential modulation of SIRT6 deacetylase and deacylase activities by lysine-based small molecules.

Mol Divers 2020 Aug 25;24(3):655-671. Epub 2019 Jun 25.

Department of Experimental Medicine, Section of Biochemistry, and CEBR, University of Genoa, V.le Benedetto XV 1, 16132, Genoa, Italy.

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August 2020

Elicited ROS Scavenging Activity, Photoprotective, and Wound-Healing Properties of Collagen-Derived Peptides from the Marine Sponge .

Mar Drugs 2018 Nov 23;16(12). Epub 2018 Nov 23.

Department of Earth, Environment and Life Sciences (DISTAV), University of Genova, Via Pastore 3, 16132 Genova, Italy.

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November 2018

Identification of a high affinity binding site for abscisic acid on human lanthionine synthetase component C-like protein 2.

Int J Biochem Cell Biol 2018 04 5;97:52-61. Epub 2018 Feb 5.

Department of Pharmacy, Section of Medicinal Chemistry, School of Medical and Pharmaceutical Sciences, University of Genoa, Viale Benedetto XV 3, 16132, Genoa, Italy. Electronic address:

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April 2018

Synthesis and biological evaluation of novel thiazole- VX-809 hybrid derivatives as F508del correctors by QSAR-based filtering tools.

Eur J Med Chem 2018 Jan 8;144:179-200. Epub 2017 Dec 8.

Department of Experimental Medicine, Section of Biochemistry, University of Genoa, Viale Benedetto XV 1, 16132 Genoa, Italy; Center of Excellence for Biomedical Research (CEBR), University of Genoa, Viale Benedetto XV 9, 16132 Genoa, Italy. Electronic address:

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January 2018

Di-acetyl creatine ethyl ester, a new creatine derivative for the possible treatment of creatine transporter deficiency.

Neurosci Lett 2018 02 8;665:217-223. Epub 2017 Dec 8.

Department of Neuroscience, Ophthalmology, Genetics, Maternal-Infantile Sciences (DINOGMI), University of Genova, Largo Paolo Daneo 3, 16132 Genova, Italy; Ospedale Policlinico San Martino, Genova, Italy. Electronic address:

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February 2018

A Novel Method to Synthesize Phosphocreatine and Phosphocreatine Prodrugs.

Med Chem 2018 ;14(4):387-393

Department of Experimental Medicine, Section of Biochemistry, University of Genoa, Viale Benedetto XV 1, 16132 Genoa, Italy.

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August 2018

Effects on Energy Metabolism of Two Guanidine Molecules, (Boc) -Creatine and Metformin.

J Cell Biochem 2017 09 13;118(9):2700-2711. Epub 2017 Feb 13.

Department of Neuroscience, Ophthalmology, Genetics, Maternal-Infantile Sciences, University of Genova, Largo Paolo Daneo 3, Genova 16132, Italy.

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September 2017

CD20-Mimotope Peptide Active Immunotherapy in Systemic Lupus Erythematosus and a Reappraisal of Vaccination Strategies in Rheumatic Diseases.

Clin Rev Allergy Immunol 2017 Apr;52(2):217-233

Department of Biomedical Sciences and Oncology (DIMO), Systemic Rheumatic and Autoimmune Diseases, University of Bari Medical School, Piazza G. Cesare 11, 70124, Bari, Italy.

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April 2017

Quinazolinedione SIRT6 inhibitors sensitize cancer cells to chemotherapeutics.

Eur J Med Chem 2015 Sep 14;102:530-9. Epub 2015 Aug 14.

Department of Experimental, Diagnostic and Specialty Medicine (DIMES), Alma Mater Studiorum, University of Bologna, Via S. Giacomo 14, 40126 Bologna, Italy; Institute of Organic Synthesis and Photoreactivity (ISOF), National Research Council (CNR), Via P. Gobetti 101, 40129 Bologna, Italy. Electronic address:

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September 2015

Synthesis and structure-activity relationship of aminoarylthiazole derivatives as correctors of the chloride transport defect in cystic fibrosis.

Eur J Med Chem 2015 Jun 28;99:14-35. Epub 2015 May 28.

Department of Experimental Medicine, Section of Biochemistry, University of Genoa, Viale Benedetto XV 1, 16132 Genoa, Italy; Center of Excellence for Biomedical Research (CEBR), University of Genoa, Viale Benedetto XV 5, 16132 Genoa, Italy. Electronic address:

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June 2015

Abscisic acid transport in human erythrocytes.

J Biol Chem 2015 May 6;290(21):13042-52. Epub 2015 Apr 6.

From the Department of Experimental Medicine, Section of Biochemistry, and.

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May 2015