Enrico Maggi

Enrico Maggi

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Enrico Maggi

Enrico Maggi

Publications by authors named "Enrico Maggi"

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Desensitization modulates humoral and cellular immune response to infliximab in a patient with an immediate hypersensitivity reaction.

J Allergy Clin Immunol Pract 2020 Jan 13. Epub 2020 Jan 13.

Immunoallergology Unit, Department of Medicine and Geriatrics, Careggi University Hospital, Florence, Italy.

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http://dx.doi.org/10.1016/j.jaip.2019.12.040DOI Listing
January 2020

Systemic hypereosinophilic syndromes: when autoimmunity is Th2 mediated.

Curr Opin Allergy Clin Immunol 2020 Jan 27. Epub 2020 Jan 27.

Immunoallergology Unit, AOU Careggi, University of Florence, Florence.

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http://dx.doi.org/10.1097/ACI.0000000000000614DOI Listing
January 2020

Hypersensitivity reactions to biologics used in rheumatology.

Expert Rev Clin Immunol 2019 Dec 30;15(12):1263-1271. Epub 2019 Oct 30.

Immunoallergology Unit, Department of Medicine and Geriatrics, Careggi University Hospital, Florence, Italy.

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http://dx.doi.org/10.1080/1744666X.2020.1684264DOI Listing
December 2019

Eosinophils, the IL-5/IL-5Rα axis, and the biologic effects of benralizumab in severe asthma.

Respir Med 2019 Nov - Dec;160:105819. Epub 2019 Nov 11.

Immunoallergology Unit, Azienda Ospedaliero-Universitaria Careggi, Florence, Italy.

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http://dx.doi.org/10.1016/j.rmed.2019.105819DOI Listing
November 2019

Decreased circulating lymphatic endothelial progenitor cells in digital ulcer-complicated systemic sclerosis.

Ann Rheum Dis 2019 04 12;78(4):575-577. Epub 2018 Oct 12.

Department of Experimental and Clinical Medicine, Division of Rheumatology, University of Florence, Florence, Italy.

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http://ard.bmj.com/lookup/doi/10.1136/annrheumdis-2018-21424
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http://dx.doi.org/10.1136/annrheumdis-2018-214240DOI Listing
April 2019

Rapid clinical improvement of atopic dermatitis in an Omalizumab treated patient.

Clin Mol Allergy 2019 12;17. Epub 2019 Mar 12.

2Immunoallergology Unit, Department of Biomedicine, Azienda Ospedaliero-Universitaria Careggi, Florence, Italy.

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https://clinicalmolecularallergy.biomedcentral.com/articles/
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http://dx.doi.org/10.1186/s12948-019-0109-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6413441PMC
March 2019

The percentage of patients achieving complete remission of urticaria increases with repeated courses of treatment.

J Allergy Clin Immunol Pract 2019 Jan 2;7(1):339-340. Epub 2018 Jul 2.

Immunoallergology Unit, Careggi University Hospital, Florence, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.jaip.2018.06.011DOI Listing
January 2019

Omalizumab dampens type 2 inflammation in a group of long-term treated asthma patients and detaches IgE from FcεRI.

Eur J Immunol 2018 12 9;48(12):2005-2014. Epub 2018 Oct 9.

Department of Experimental and Clinical Medicine and DENOTHE Center, University of Florence, Florence, Italy.

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http://dx.doi.org/10.1002/eji.201847668DOI Listing
December 2018

Tocilizumab in Giant Cell Arteritis: A Real-Life Retrospective Study.

Angiology 2018 Oct 17;69(9):763-769. Epub 2018 Jan 17.

1 Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy.

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http://dx.doi.org/10.1177/0003319717753223DOI Listing
October 2018

[Immunological mechanisms of allergic diseases].

Authors:
Enrico Maggi

G Ital Med Lav Ergon 2017 11;39(3):168-171

Ordinario di Medicina Interna, Dipartimento di Medicina Sperimentale e Clinica, Università degli Studi di Firenze.

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November 2017

Angiogenic T cell expansion correlates with severity of peripheral vascular damage in systemic sclerosis.

PLoS One 2017 10;12(8):e0183102. Epub 2017 Aug 10.

Department of Experimental and Clinical Medicine, Section of Internal Medicine, Azienda Ospedaliero-Universitaria Careggi (AOUC), University of Florence, Florence, Italy.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0183102PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5552290PMC
October 2017

IL-10-Producing Infliximab-Specific T Cells Regulate the Antidrug T Cell Response in Exposed Patients.

J Immunol 2017 08 17;199(4):1283-1289. Epub 2017 Jul 17.

Unit of Immunoallergology, Careggi University Hospital, Careggi, Florence, 50134 Italy; and.

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http://dx.doi.org/10.4049/jimmunol.1700008DOI Listing
August 2017

Human circulating group 2 innate lymphoid cells can express CD154 and promote IgE production.

J Allergy Clin Immunol 2017 Mar 27;139(3):964-976.e4. Epub 2016 Jul 27.

Department of Experimental and Clinical Medicine and DENOTHE Center, Florence, Italy; Regenerative Medicine Unit and Immunology and Cellular Therapy Unit of Azienda Ospedaliera Careggi, Florence, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2016.06.032DOI Listing
March 2017

An overview on safety of monoclonal antibodies.

Curr Opin Allergy Clin Immunol 2016 12;16(6):576-581

aImmunoallergology Unit, AOU Careggi bDepartment of Experimental and Clinical Medicine, Centre of Excellence DENOTHE, University of Florence, Florence, Italy.

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http://pdfs.journals.lww.com/co-allergy/2016/12000/An_overvi
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http://dx.doi.org/10.1097/ACI.0000000000000315DOI Listing
December 2016

Influence of anti-TNF immunogenicity on safety in rheumatic disease: a narrative review.

Expert Opin Drug Saf 2016 Dec;15(sup1):3-10

a Immunoallergology Unit, Department of Biomedicine , Azienda Ospedaliero-Universitaria Careggi , Florence , Italy.

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http://dx.doi.org/10.1080/14740338.2016.1221398DOI Listing
December 2016

How the immune system responds to therapeutic biological agents.

J Int Med Res 2016 Sep;44(1 suppl):38-42

Department of Biomedicine, Immunoallergology Section, AOU Careggi, University of Florence, Florence, Italy.

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http://dx.doi.org/10.1177/0300060515593248DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5536528PMC
September 2016

The safety of monoclonal antibodies in asthma.

Expert Opin Drug Saf 2016 Aug;15(8):1087-95

a Allergy and Respiratory Diseases , IRCCS San Martino, IST, University of Genoa , Genova , Italy.

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http://dx.doi.org/10.1080/14740338.2016.1186641DOI Listing
August 2016

European medicines agency guideline for biological medicinal products: a further step for a safe use of biosimilars.

Clin Mol Allergy 2015 15;13(1). Epub 2015 May 15.

Department of Clinical and Experimental Medicine, University of Florence, Florence, Italy.

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http://dx.doi.org/10.1186/s12948-015-0010-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4432880PMC
May 2015

Demethylation of the RORC2 and IL17A in human CD4+ T lymphocytes defines Th17 origin of nonclassic Th1 cells.

J Immunol 2015 Apr 4;194(7):3116-26. Epub 2015 Mar 4.

Department of Experimental and Clinical Medicine, University of Florence, Florence 50134, Italy; DENOTHE Center, University of Florence, Florence 50134, Italy; Regenerative Medicine Unit, Careggi University Hospital, Florence 50134, Italy;

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http://dx.doi.org/10.4049/jimmunol.1401303DOI Listing
April 2015

Welcome to a new era for Clinical and Molecular Allergy.

Authors:
Enrico Maggi

Clin Mol Allergy 2015 15;13(1). Epub 2015 Apr 15.

Allergology and Clinical Immunology Department of Clinical and Experimental Medicine, University of Firenze, Largo Brambilla 3, 50134 Firenze, Italy.

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http://dx.doi.org/10.1186/s12948-015-0014-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4397666PMC
April 2015

Th17 and non-classic Th1 cells in chronic inflammatory disorders: two sides of the same coin.

Int Arch Allergy Immunol 2014 12;164(3):171-7. Epub 2014 Jul 12.

Department of Experimental and Clinical Medicine and DENOTHE Center, University of Florence, and Units of Regenerative Medicine, and Immunology and Cellular Therapy, Azienda Ospedaliera Careggi, Florence, Italy.

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http://dx.doi.org/10.1159/000363502DOI Listing
January 2015

Mechanisms of action of Ig preparations: immunomodulatory and anti-inflammatory effects.

Front Immunol 2014 12;5:690. Epub 2015 Jan 12.

Immunoallergology Unit, Department of Biomedicine, Policlinico di Careggi , Florence , Italy.

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http://dx.doi.org/10.3389/fimmu.2014.00690DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4290674PMC
January 2015

Manifestations of Antidrug Antibodies Response: Hypersensitivity and Infusion Reactions.

J Interferon Cytokine Res 2014 Dec;34(12):946-952

1 Immunoallergology Unit, Department of Biomedicine, Azienda Ospedaliero-Universitaria Careggi , Florence, Italy .

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http://dx.doi.org/10.1089/jir.2012.0139DOI Listing
December 2014

Assays and strategies for immunogenicity assessment of biological agents.

Drug Dev Res 2014 Nov;75 Suppl 1:S4-6

Center for Research, Transfer and High Education DENOTHE, University of Florence, Florence, 50134, Italy.

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http://doi.wiley.com/10.1002/ddr.21184
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http://dx.doi.org/10.1002/ddr.21184DOI Listing
November 2014

Perspectives in vaccine adjuvants for allergen-specific immunotherapy.

Immunol Lett 2014 Oct 19;161(2):207-10. Epub 2013 Dec 19.

DENOTHE Center, Department of Experimental and Clinical Medicine, University of Florence, Viale Pieraccini 6, 50134 Florence, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.imlet.2013.12.011DOI Listing
October 2014

Human Th1 dichotomy: origin, phenotype and biologic activities.

Immunology 2014 Oct 5. Epub 2014 Oct 5.

Department of Experimental and Clinical Medicine and DENOTHE Center, University of Florence, Florence, 50134, Italy; Regenerative Medicine Unit and Immunology and Cellular Therapy Unit of Azienda Ospedaliera Careggi, Florence, 50134, Italy.

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http://dx.doi.org/10.1111/imm.12399DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4557671PMC
October 2014

Cellular and humoral immune responses during tuberculosis infection: useful knowledge in the era of biological agents.

J Rheumatol Suppl 2014 May;91:17-23

Address correspondence to Dr. Matucci, Immunoallergology Unit, Department of Biomedicine, Viale Morgagni 85, Florence 50134, Italy. E-mail:

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http://www.jrheum.org/cgi/doi/10.3899/jrheum.140098
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http://dx.doi.org/10.3899/jrheum.140098DOI Listing
May 2014

Hapten-specific TH17 cells in the peripheral blood of β-lactam-induced AGEP.

Allergol Int 2014 Mar 25;63(1):129-31. Epub 2013 Dec 25.

Center of High Excellence, Transfer and Education DENOTHE, University of Florence, Florence, Italy.

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http://dx.doi.org/10.2332/allergolint.13-LE-0582DOI Listing
March 2014

HLA-G5 induces IL-4 secretion critical for successful pregnancy through differential expression of ILT2 receptor on decidual CD4⁺ T cells and macrophages.

J Immunol 2013 Oct 30;191(7):3651-62. Epub 2013 Aug 30.

Department of Experimental and Clinical Medicine, Center of excellence for the study at molecular and clinical level of chronic, degenerative and neoplastic diseases to develop novel therapies, University of Florence, 50134 Florence, Italy;

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http://dx.doi.org/10.4049/jimmunol.1300567DOI Listing
October 2013

CD4+CD161+ T lymphocytes infiltrate Crohn's disease-associated perianal fistulas and are reduced by anti-TNF-α local therapy.

Int Arch Allergy Immunol 2013 15;161(1):81-6. Epub 2012 Dec 15.

Center for Research, Transfer and High Education DENOTHE, University of Florence, Florence, Italy.

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http://dx.doi.org/10.1159/000343467DOI Listing
September 2013

A novel allergen-adjuvant conjugate suitable for specific immunotherapy of respiratory allergy.

J Allergy Clin Immunol 2013 Jul 14;132(1):84-92. Epub 2013 Mar 14.

Department of Experimental and Clinical Medicine, Centre for Research, Transfer and High Education DENOTHE, University of Florence, Florence, Italy.

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http://dx.doi.org/10.1016/j.jaci.2013.01.030DOI Listing
July 2013

Main features of human T helper 17 cells.

Ann N Y Acad Sci 2013 May;1284:66-70

Laboratory of Immunology, Allergology and Cellular Therapies, Department of Internal Medicine and Denothe Center, University of Florence, Italy.

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http://dx.doi.org/10.1111/nyas.12075DOI Listing
May 2013

Kimura's disease: case report of an Italian young male and response to oral cyclosporine A in an 8 years follow-up.

Clin Rheumatol 2013 Mar 19;32 Suppl 1:S55-7. Epub 2010 Apr 19.

Department of Biomedicine, Allergology and Clinical Immunology, University of Florence, V.le Morgagni, 85, 50134 Florence, Italy.

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http://dx.doi.org/10.1007/s10067-010-1449-8DOI Listing
March 2013

Drug-specific Th2 cells and IgE antibodies in a patient with anaphylaxis to rituximab.

Int Arch Allergy Immunol 2012 22;159(3):321-6. Epub 2012 Jun 22.

Immunoallergology Unit, Department of Biomedicine, Azienda Ospedaliero-Universitaria Careggi, Florence, Italy. vultaggioa @ aou-careggi.toscana.it

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http://dx.doi.org/10.1159/000336839DOI Listing
December 2012

Distinctive features of classic and nonclassic (Th17 derived) human Th1 cells.

Eur J Immunol 2012 Dec 25;42(12):3180-8. Epub 2012 Oct 25.

Department of Internal Medicine and DENOTHE Center, University of Florence, Firenze, Italy.

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http://dx.doi.org/10.1002/eji.201242648DOI Listing
December 2012

Defining the human T helper 17 cell phenotype.

Trends Immunol 2012 Oct 7;33(10):505-12. Epub 2012 Jun 7.

Department of Internal Medicine and DENOTHE Center, University of Florence, 50134 Firenze, Italy.

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http://dx.doi.org/10.1016/j.it.2012.05.004DOI Listing
October 2012

Multiorgan infiltration by CD8+ T cells and 1p;16p translocation in a patient with hypogammaglobulinemia and a reduced number of B cells.

Int Arch Allergy Immunol 2012 26;158(2):206-10. Epub 2012 Jan 26.

Immunoallergology Unit, Department of Biomedicine, AOU Careggi, Florence, Italy.

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http://dx.doi.org/10.1159/000331117DOI Listing
August 2012

T-cell responses during allergen-specific immunotherapy.

Curr Opin Allergy Clin Immunol 2012 Feb;12(1):1-6

Section of Immunoallergology, Department of Internal Medicine, Center of Research, Transfer and High Education DENOTHE, University of Florence, Florence, Italy.

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http://dx.doi.org/10.1097/ACI.0b013e32834ecc9aDOI Listing
February 2012

Asthma: developments in targeted therapy.

Expert Rev Clin Immunol 2012 Jan;8(1):13-5

Department of Biomedicine, Immunoallergology Unit, Azienda Ospedaliero-Universitaria Careggi, Florence, Italy.

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http://dx.doi.org/10.1586/eci.11.71DOI Listing
January 2012

Evidence of the transient nature of the Th17 phenotype of CD4+CD161+ T cells in the synovial fluid of patients with juvenile idiopathic arthritis.

Arthritis Rheum 2011 Aug;63(8):2504-15

University of Florence and Excellence Centre for Research, Transfer and Higher Education on Chronic, Inflammatory, Degenerative and Neoplastic Disorders for the Development of Novel Therapies, Florence, Italy.

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http://dx.doi.org/10.1002/art.30332DOI Listing
August 2011

The ImmunoCAP ISAC molecular allergology approach in adult multi-sensitized Italian patients with respiratory symptoms.

Clin Biochem 2011 Aug 19;44(12):1005-11. Epub 2011 May 19.

Dipartimento di Medicina Sperimentale, UO Laboratorio di Analisi, Istituto Giannina Gaslini, Genoa, Italy.

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http://dx.doi.org/10.1016/j.clinbiochem.2011.05.007DOI Listing
August 2011

Immediate adverse reactions to biologicals: from pathogenic mechanisms to prophylactic management.

Curr Opin Allergy Clin Immunol 2011 Jun;11(3):262-8

Department of Biomedicine, Immunoallergology Unit, Azienda Ospedaliero-Universitaria Careggi, Italy.

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http://dx.doi.org/10.1097/ACI.0b013e3283464bcdDOI Listing
June 2011

Acute infusion reactions induced by monoclonal antibody therapy.

Expert Rev Clin Immunol 2011 Jan;7(1):55-63

Center for Research, Transfer and High Education DENOTHE, University of Florence, Policlinico di Careggi, Viale Morgagni 85, 50134 Florence, Italy.

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http://dx.doi.org/10.1586/eci.10.90DOI Listing
January 2011

Properties and origin of human Th17 cells.

Mol Immunol 2009 Nov 3;47(1):3-7. Epub 2009 Feb 3.

Department of Internal Medicine and Excellence Center DENOTHE, University of Florence, Firenze-50134, Italy.

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http://dx.doi.org/10.1016/j.molimm.2008.12.019DOI Listing
November 2009

Type 17 T helper cells-origins, features and possible roles in rheumatic disease.

Nat Rev Rheumatol 2009 Jun;5(6):325-31

Department of Internal Medicine, University of Florence, Firenze 50134, Italy.

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http://dx.doi.org/10.1038/nrrheum.2009.80DOI Listing
June 2009

Human Th17 cells: are they different from murine Th17 cells?

Eur J Immunol 2009 Mar;39(3):637-40

Center of Excellence for Research, Transfer of Research and High Education for the Development of Novel therapies, University of Florence, Florence, Italy.

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http://dx.doi.org/10.1002/eji.200839050DOI Listing
March 2009

The phenotype of human Th17 cells and their precursors, the cytokines that mediate their differentiation and the role of Th17 cells in inflammation.

Int Immunol 2008 Nov 26;20(11):1361-8. Epub 2008 Sep 26.

Center of Excellence for Research, Transfer and High Education on Chronic, Inflammatory, Degenerative and Neoplastic Disorders for the Development of Novel Therapies, University of Florence, Florence, Italy.

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http://dx.doi.org/10.1093/intimm/dxn106DOI Listing
November 2008

Demonstration of circulating allergen-specific CD4+CD25highFoxp3+ T-regulatory cells in both nonatopic and atopic individuals.

J Allergy Clin Immunol 2007 Aug 2;120(2):429-36. Epub 2007 Jul 2.

Excellence Center for Research, Transfer, and High Education DENOthe, University of Florence, Italy.

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http://dx.doi.org/10.1016/j.jaci.2007.05.002DOI Listing
August 2007

Phenotypic and functional features of human Th17 cells.

J Exp Med 2007 Aug 16;204(8):1849-61. Epub 2007 Jul 16.

Center for Research, Transfer and High Education on Chronic, Inflammatory, Degenerative and Neoplastic Disorders (DENOTHE), University of Florence, Florence 50134, Italy.

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http://dx.doi.org/10.1084/jem.20070663DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118657PMC
August 2007

Tako-Tsubo-like syndrome during anaphylactic reaction.

Eur J Heart Fail 2007 Feb 7;9(2):209-11. Epub 2006 Jul 7.

Department of Biomedicine, Unit of Immunology and Cellular Therapy, University of Florence, Policlinico di Careggi, Viale Morgagni 85, 50134 Florence, Italy.

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http://doi.wiley.com/10.1016/j.ejheart.2006.05.011
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http://dx.doi.org/10.1016/j.ejheart.2006.05.011DOI Listing
February 2007

TLR7/8 agonists impair monocyte-derived dendritic cell differentiation and maturation.

J Leukoc Biol 2007 Jan 5;81(1):221-8. Epub 2006 Oct 5.

INSERM U662, Université Paris 7, Institut Universitaire d'Hématologie, Centre Hayem, Hôpital Saint-Louis, 1, Avenue Claude Vellefaux, 75010 Paris, France.

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http://dx.doi.org/10.1189/jlb.0705385DOI Listing
January 2007

Hypergravity speeds up the development of T-lymphocyte motility.

Eur Biophys J 2006 May 8;35(5):393-400. Epub 2006 Mar 8.

LENS (European Laboratory for Non-Linear Spectroscopy), University of Florence, Sesto Fiorentino, FI, Italy.

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http://dx.doi.org/10.1007/s00249-006-0046-xDOI Listing
May 2006

Thymic regulatory T cells.

Autoimmun Rev 2005 Nov;4(8):579-86

Center of Research, Transfer, High Education MCIDNENT, University of Florence, Firenze, Italy.

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http://dx.doi.org/10.1016/j.autrev.2005.04.010DOI Listing
November 2005

Vascular endothelial growth factor receptor-2 and low affinity VEGF binding sites on human glomerular endothelial cells: Biological effects and advanced glycosilation end products modulation.

Microvasc Res 2005 Nov;70(3):179-88

Department of Clinical Pathophysiology, Endocrinology Unit, Diabetes and Metabolic Diseases Section, University of Florence, viale Pieraccini 6-501354 Florence, Italy.

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http://dx.doi.org/10.1016/j.mvr.2005.10.001DOI Listing
November 2005