Emmie de Wit

Emmie de Wit

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Emmie de Wit

Emmie de Wit

Publications by authors named "Emmie de Wit"

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Onward transmission of viruses: how do viruses emerge to cause epidemics after spillover?

Philos Trans R Soc Lond B Biol Sci 2019 Sep 12;374(1782):20190017. Epub 2019 Aug 12.

Baker Institute for Animal Health, Department of Microbiology and Immunology, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853, USA.

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http://dx.doi.org/10.1098/rstb.2019.0017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6711314PMC
September 2019

Dose-response and transmission: the nexus between reservoir hosts, environment and recipient hosts.

Philos Trans R Soc Lond B Biol Sci 2019 Sep 12;374(1782):20190016. Epub 2019 Aug 12.

Environmental Futures Research Institute, Griffith University, Kessels Road, Nathan, Queensland 4111, Australia.

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http://dx.doi.org/10.1098/rstb.2019.0016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6711301PMC
September 2019

The vesicular stomatitis virus-based Ebola virus vaccine: From concept to clinical trials.

Hum Vaccin Immunother 2018 18;14(9):2107-2113. Epub 2018 Jun 18.

a Laboratory of Virology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rocky Mountain Laboratories , Hamilton , MT , USA.

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https://www.tandfonline.com/doi/full/10.1080/21645515.2018.1
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http://dx.doi.org/10.1080/21645515.2018.1473698DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6183239PMC
May 2019

Pathogenicity and Viral Shedding of MERS-CoV in Immunocompromised Rhesus Macaques.

Front Immunol 2018 12;9:205. Epub 2018 Feb 12.

Laboratory of Virology, Division of Intramural Research, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, MT, United States.

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http://dx.doi.org/10.3389/fimmu.2018.00205DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5816332PMC
April 2019

Prophylactic efficacy of a human monoclonal antibody against MERS-CoV in the common marmoset.

Antiviral Res 2019 Mar 24;163:70-74. Epub 2019 Jan 24.

Laboratory of Virology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, MT, USA. Electronic address:

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http://dx.doi.org/10.1016/j.antiviral.2019.01.016DOI Listing
March 2019

The Effect of Plasmodium on the Outcome of Ebola Virus Infection in a Mouse Model.

J Infect Dis 2018 11;218(suppl_5):S434-S437

Laboratory of Virology, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Hamilton, Montana.

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http://dx.doi.org/10.1093/infdis/jiy236DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6249605PMC
November 2018

Outbreaks in a Rapidly Changing Central Africa - Lessons from Ebola.

N Engl J Med 2018 Sep 22;379(13):1198-1201. Epub 2018 Aug 22.

From the Laboratory of Virology, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, MT (V.J.M., E.W., R.F., S.N.S.); the UK Public Health Rapid Support Team, Public Health England-London School of Hygiene and Tropical Medicine, London (D.G.B.); the University of Laval, Quebec, QC, Canada (G.K.); the Bernhard Nocht Institute for Tropical Medicine, Hamburg (C.M.-F.), the German Center for Infection Research, Hamburg (C.M.-F.), and the Institute for Tropical Medicine, University of Tübingen (F.N.) - all in Germany; the Wildlife Conservation Society, Wildlife Health Program, Bronx, NY (S.H.O.); Médecins sans Frontières, Brussels, Belgium (A.S.); the Fondation Congolaise pour la Recherche Medicale and Faculty of Sciences and Technology, University Marien Ngouabi (F.N.), and the Laboratoire National de Santé Publique, Brazzaville (J.-V.M.) - both in the Republic of the Congo; and the Ministry of Health and Social Welfare of Liberia and the Incidence Management System of Liberia, Ebola Case Management Team, Monrovia, Liberia (M.M.).

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http://www.nejm.org/doi/10.1056/NEJMp1807691
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http://dx.doi.org/10.1056/NEJMp1807691DOI Listing
September 2018

Prophylactic and therapeutic efficacy of mAb treatment against MERS-CoV in common marmosets.

Antiviral Res 2018 08 7;156:64-71. Epub 2018 Jun 7.

Laboratory of Virology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, MT, USA.

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http://dx.doi.org/10.1016/j.antiviral.2018.06.006DOI Listing
August 2018

Transmission of henipaviruses.

Curr Opin Virol 2018 02 14;28:7-11. Epub 2017 Oct 14.

Laboratory of Virology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, MT, United States. Electronic address:

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http://dx.doi.org/10.1016/j.coviro.2017.09.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5835161PMC
February 2018

Efficacy of antibody-based therapies against Middle East respiratory syndrome coronavirus (MERS-CoV) in common marmosets.

Antiviral Res 2017 07 5;143:30-37. Epub 2017 Apr 5.

Virus Ecology Unit, Laboratory of Virology, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rocky Mountain Laboratories, Hamilton, MT, USA. Electronic address:

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http://dx.doi.org/10.1016/j.antiviral.2017.03.025DOI Listing
July 2017

Dromedary camels in northern Mali have high seropositivity to MERS-CoV.

One Health 2017 Jun 10;3:41-43. Epub 2017 Mar 10.

Laboratory of Virology, National Institute for Allergy and Infectious Diseases, National Institutes of Health, Rocky Mountain Laboratories, 903 South 4th Street, Hamilton, MT 59840, USA.

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http://dx.doi.org/10.1016/j.onehlt.2017.03.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5454179PMC
June 2017

Sustained fecal-oral human-to-human transmission following a zoonotic event.

Curr Opin Virol 2017 02 23;22:1-6. Epub 2016 Nov 23.

Department of Global Health and Department of Medical Microbiology, Academic Medical Center, Amsterdam, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.coviro.2016.11.001DOI Listing
February 2017

Reply to Colebunders.

Clin Infect Dis 2017 01 9;64(2):232. Epub 2016 Nov 9.

Laboratory of Virology, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rocky Mountain Laboratories, Hamilton, Montana;

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http://dx.doi.org/10.1093/cid/ciw734DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6289505PMC
January 2017

Identifying Early Target Cells of Nipah Virus Infection in Syrian Hamsters.

PLoS Negl Trop Dis 2016 Nov 3;10(11):e0005120. Epub 2016 Nov 3.

Laboratory of Virology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, Montana, United States of America.

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http://dx.doi.org/10.1371/journal.pntd.0005120DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5094696PMC
November 2016

SARS and MERS: recent insights into emerging coronaviruses.

Nat Rev Microbiol 2016 08 27;14(8):523-34. Epub 2016 Jun 27.

Laboratory of Virology, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rocky Mountain Laboratories, Hamilton, Montana 59840, USA.

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http://dx.doi.org/10.1038/nrmicro.2016.81DOI Listing
August 2016

An Acute Immune Response to Middle East Respiratory Syndrome Coronavirus Replication Contributes to Viral Pathogenicity.

Am J Pathol 2016 Mar 24;186(3):630-8. Epub 2015 Dec 24.

Laboratory of Virology, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, NIH, Rocky Mountain Laboratories, Hamilton, Montana. Electronic address:

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http://dx.doi.org/10.1016/j.ajpath.2015.10.025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4816712PMC
March 2016

Molecular Evidence of Sexual Transmission of Ebola Virus.

N Engl J Med 2015 Dec 14;373(25):2448-54. Epub 2015 Oct 14.

From the Center for Genome Sciences (S.E.M., J.R.K., J.T.L., M.R.W., K.P., M.S.-L., G.P.) and Diagnostic Systems Division (R.J.S.), U.S. Army Medical Research Institute of Infectious Diseases, and the Division of Clinical Research, Integrated Research Facility at Fort Detrick, National Institute of Allergy and Infectious Diseases, National Institutes of Health (NIH) (J.P., L.E.H., J.H.K.) - all in Frederick, MD; the Ministry of Health and Social Welfare (T.G.N., S.B.S., M.B., F.N.K.) and the World Health Organization (WHO) (G.J.D.-W., R.M.), Monrovia, and the Liberian Institute for Biomedical Research, Charlesville (L.F., F.T., F.B.) - all in Liberia; WHO, Geneva (T.C.-L., A.G., P.F.); the Centers for Disease Control and Prevention, Atlanta (A.C., B.W.H., U.S., D.J.B., A.S.L., D.E.W., T.L., S.T.N., K.M.D.C.); Illumina, San Diego, CA (G.P.S., S.M.G.); WHO, New Delhi, India (S.A.S); Rocky Mountain Laboratories, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, NIH, Hamilton, MT (E.W., N.D., V.J.M., D.S.); Naval Medical Research Unit 3, Cairo (J.W.D.); and the Foundation Mérieux, Washington, DC (J.F.).

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http://dx.doi.org/10.1056/NEJMoa1509773DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4711355PMC
December 2015

Birth and pathogenesis of rogue respiratory viruses.

Annu Rev Pathol 2015 24;10:449-71. Epub 2014 Nov 24.

Laboratory of Virology, Division of Intramural Research, Rocky Mountain Laboratories, National Institute for Allergy and Infectious Diseases, National Institutes of Health, Hamilton, Montana; email: , ,

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http://dx.doi.org/10.1146/annurev-pathol-012414-040501DOI Listing
June 2015

Animal models of disease shed light on Nipah virus pathogenesis and transmission.

J Pathol 2015 Jan;235(2):196-205

Laboratory of Virology, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rocky Mountain Laboratories, Hamilton, MT, USA.

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http://dx.doi.org/10.1002/path.4444DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4268059PMC
January 2015

Infection with MERS-CoV causes lethal pneumonia in the common marmoset.

PLoS Pathog 2014 Aug 21;10(8):e1004250. Epub 2014 Aug 21.

Virus Ecology Unit, Laboratory of Virology, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rocky Mountain Laboratories, Hamilton, Montana, United States of America.

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http://dx.doi.org/10.1371/journal.ppat.1004250DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4140844PMC
August 2014

Foodborne transmission of nipah virus in Syrian hamsters.

PLoS Pathog 2014 Mar 13;10(3):e1004001. Epub 2014 Mar 13.

Laboratory of Virology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, Montana, United States of America.

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http://dx.doi.org/10.1371/journal.ppat.1004001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3953481PMC
March 2014

MERS-CoV: the intermediate host identified?

Lancet Infect Dis 2013 Oct 9;13(10):827-8. Epub 2013 Aug 9.

Disease Modeling and Transmission Unit, Laboratory of Virology, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rocky Mountain Laboratories, Hamilton, MT, USA.

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http://dx.doi.org/10.1016/S1473-3099(13)70193-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4798748PMC
October 2013

Treatment with interferon-α2b and ribavirin improves outcome in MERS-CoV-infected rhesus macaques.

Nat Med 2013 Oct 8;19(10):1313-7. Epub 2013 Sep 8.

Disease Modeling and Transmission Unit, Laboratory of Virology, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rocky Mountain Laboratories, Hamilton, Montana, USA.

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http://dx.doi.org/10.1038/nm.3362DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4093902PMC
October 2013

Middle East respiratory syndrome coronavirus (MERS-CoV) causes transient lower respiratory tract infection in rhesus macaques.

Proc Natl Acad Sci U S A 2013 Oct 23;110(41):16598-603. Epub 2013 Sep 23.

Laboratory of Virology, Rocky Mountain Veterinary Branch, and Microscopy Unit, Research Technologies Branch, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, MT 59840.

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http://dx.doi.org/10.1073/pnas.1310744110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3799368PMC
October 2013

Comparison of the pathogenicity of Nipah virus isolates from Bangladesh and Malaysia in the Syrian hamster.

PLoS Negl Trop Dis 2013 17;7(1):e2024. Epub 2013 Jan 17.

Laboratory of Virology, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rocky Mountain Laboratories, Hamilton, Montana, USA.

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http://dx.doi.org/10.1371/journal.pntd.0002024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3547834PMC
June 2013

Rapid Nipah virus entry into the central nervous system of hamsters via the olfactory route.

Sci Rep 2012 15;2:736. Epub 2012 Oct 15.

Laboratory of Virology, Microscopy Unit, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, MT, USA.

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http://dx.doi.org/10.1038/srep00736DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3471094PMC
March 2013

The immune response to Nipah virus infection.

Arch Virol 2012 Sep 6;157(9):1635-41. Epub 2012 Jun 6.

Laboratory of Virology, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, MT, USA.

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http://link.springer.com/10.1007/s00705-012-1352-5
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http://dx.doi.org/10.1007/s00705-012-1352-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3432143PMC
September 2012

Nipah virus transmission in a hamster model.

PLoS Negl Trop Dis 2011 Dec 13;5(12):e1432. Epub 2011 Dec 13.

Laboratory of Virology, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, Montana, USA.

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http://dx.doi.org/10.1371/journal.pntd.0001432DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3236726PMC
December 2011

Assessment of rodents as animal models for Reston ebolavirus.

J Infect Dis 2011 Nov;204 Suppl 3:S968-72

Laboratory of Virology, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, Montana, USA.

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http://dx.doi.org/10.1093/infdis/jir330DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3189989PMC
November 2011

Tackling Ebola: new insights into prophylactic and therapeutic intervention strategies.

Genome Med 2011 Jan 27;3(1). Epub 2011 Jan 27.

Laboratory of Virology, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, 903 South 4th Street, MT 59840, USA.

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http://genomemedicine.biomedcentral.com/articles/10.1186/gm2
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http://dx.doi.org/10.1186/gm219DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3092090PMC
January 2011

Molecular determinants of adaptation of highly pathogenic avian influenza H7N7 viruses to efficient replication in the human host.

J Virol 2010 Feb 25;84(3):1597-606. Epub 2009 Nov 25.

National Influenza Center and Department of Virology, Erasmus Medical Center, P.O. Box 2040, 3000 CA Rotterdam, The Netherlands.

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http://dx.doi.org/10.1128/JVI.01783-09DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2812334PMC
February 2010

Pathogenicity of highly pathogenic avian influenza virus in mammals.

Vaccine 2008 Sep;26 Suppl 4:D54-8

Department of Virology and National Influenza Center, Erasmus Medical Center, 3000 CA Rotterdam, The Netherlands.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2605681PMC
http://dx.doi.org/10.1016/j.vaccine.2008.07.072DOI Listing
September 2008

Emerging influenza.

J Clin Virol 2008 Jan;41(1):1-6

Department of Virology and National Influenza Center, Erasmus Medical Center, P.O. Box 2040, 3000CA Rotterdam, The Netherlands.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2768345PMC
January 2008

The molecular basis of the pathogenicity of the Dutch highly pathogenic human influenza A H7N7 viruses.

J Infect Dis 2007 Jul 4;196(2):258-65. Epub 2007 Jun 4.

Department of Virology and National Influenza Center, Erasmus Medical Center, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1086/518792DOI Listing
July 2007

A reverse-genetics system for Influenza A virus using T7 RNA polymerase.

J Gen Virol 2007 Apr;88(Pt 4):1281-7

National Influenza Center, Department of Virology and Postgraduate School of Molecular Medicine, Erasmus MC, PO Box 1738, 3000 DR Rotterdam, The Netherlands.

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http://dx.doi.org/10.1099/vir.0.82452-0DOI Listing
April 2007

Rapid sequencing of the non-coding regions of influenza A virus.

J Virol Methods 2007 Jan 23;139(1):85-9. Epub 2006 Oct 23.

National Influenza Center and Department of Virology, Erasmus MC, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1016/j.jviromet.2006.09.015DOI Listing
January 2007

Evidence for specific packaging of the influenza A virus genome from conditionally defective virus particles lacking a polymerase gene.

Vaccine 2006 Nov 21;24(44-46):6647-50. Epub 2006 Jun 21.

National Influenza Center and Department of Virology, Erasmus MC, P.O. Box 1738, 3000 DR Rotterdam, The Netherlands.

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http://dx.doi.org/10.1016/j.vaccine.2006.06.001DOI Listing
November 2006

H5N1 Virus Attachment to Lower Respiratory Tract.

Science 2006 Apr 23;312(5772):399. Epub 2006 Mar 23.

Department of Virology, Erasmus Medical Center, 3015 GE Rotterdam, Netherlands.

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http://dx.doi.org/10.1126/science.1125548DOI Listing
April 2006

Role of the pilot protein YscW in the biogenesis of the YscC secretin in Yersinia enterocolitica.

J Bacteriol 2004 Aug;186(16):5366-75

Department of Molecular Microbiology and Institute of Biomembranes, Utrecht University, 3584 CH Utrecht, The Netherlands.

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http://dx.doi.org/10.1128/JB.186.16.5366-5375.2004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC490869PMC
August 2004

Efficient generation and growth of influenza virus A/PR/8/34 from eight cDNA fragments.

Virus Res 2004 Jul;103(1-2):155-61

National Influenza Center and Department of Virology, Erasmus MC, P.O. Box 1738, 3000 DR Rotterdam, The Netherlands.

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http://dx.doi.org/10.1016/j.virusres.2004.02.028DOI Listing
July 2004