Publications by authors named "Emmet Jordan"

24Publications

AKT1 E17K Inhibits Cancer Cell Migration by Abrogating β-Catenin Signaling.

Authors:
Sizhi Paul Gao Amber J Kiliti Kai Zhang Naresh Vasani Ninghui Mao Emmet Jordan Hannah C Wise Tripti Shrestha Bhattarai Wenhuo Hu Madeline Dorso James A Rodrigues Kwanghee Kim Aphrothiti J Hanrahan Pedram Razavi Brett Carver Sarat Chandarlapaty Jorge S Reis-Filho Barry S Taylor David B Solit

Mol Cancer Res 2020 Dec 10. Epub 2020 Dec 10.

Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, New York.

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December 2020

Frequency and outcomes of brain metastases in patients with HER2-mutant lung cancers.

Authors:
Michael Offin Daniel Feldman Ai Ni Mackenzie L Myers W Victoria Lai Elena Pentsova Adrienne Boire Mariza Daras Emmet J Jordan David B Solit Maria E Arcila David R Jones James M Isbell Kathryn Beal Robert J Young Charles M Rudin Gregory J Riely Alexander Drilon Viviane Tabar Lisa M DeAngelis Helena A Yu Mark G Kris Bob T Li

Cancer 2019 12 30;125(24):4380-4387. Epub 2019 Aug 30.

Thoracic Oncology Service, Division of Solid Tumor Oncology, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York.

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December 2019

Second-line chemotherapy in advanced biliary cancers: A retrospective, multicenter analysis of outcomes.

Authors:
Maeve A Lowery Laura W Goff Bridget P Keenan Emmet Jordan Rui Wang Andrea G Bocobo Joanne F Chou Eileen M O'Reilly James J Harding Nancy Kemeny Marianela Capanu Ann C Griffin Joseph McGuire Alan P Venook Ghassan K Abou-Alfa Robin K Kelley

Cancer 2019 Dec 27;125(24):4426-4434. Epub 2019 Aug 27.

Helen Diller Family Comprehensive Cancer Center, University of California San Francisco, San Francisco, California.

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December 2019

Harnessing Clinical Sequencing Data for Survival Stratification of Patients with Metastatic Lung Adenocarcinomas.

Authors:
Ronglai Shen Axel Martin Ai Ni Matthew Hellmann Kathryn C Arbour Emmet Jordan Arshi Arora Ryan Ptashkin Ahmet Zehir Mark G Kris Charles M Rudin Michael F Berger David B Solit Venkatraman E Seshan Maria Arcila Marc Ladanyi Gregory J Riely

JCO Precis Oncol 2019 28;3. Epub 2019 Mar 28.

Thoracic Oncology Service, Division of Solid Tumor Oncology, Department of Medicine.

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March 2019

Tumor mutational load predicts survival after immunotherapy across multiple cancer types.

Authors:
Robert M Samstein Chung-Han Lee Alexander N Shoushtari Matthew D Hellmann Ronglai Shen Yelena Y Janjigian David A Barron Ahmet Zehir Emmet J Jordan Antonio Omuro Thomas J Kaley Sviatoslav M Kendall Robert J Motzer A Ari Hakimi Martin H Voss Paul Russo Jonathan Rosenberg Gopa Iyer Bernard H Bochner Dean F Bajorin Hikmat A Al-Ahmadie Jamie E Chaft Charles M Rudin Gregory J Riely Shrujal Baxi Alan L Ho Richard J Wong David G Pfister Jedd D Wolchok Christopher A Barker Philip H Gutin Cameron W Brennan Viviane Tabar Ingo K Mellinghoff Lisa M DeAngelis Charlotte E Ariyan Nancy Lee William D Tap Mrinal M Gounder Sandra P D'Angelo Leonard Saltz Zsofia K Stadler Howard I Scher Jose Baselga Pedram Razavi Christopher A Klebanoff Rona Yaeger Neil H Segal Geoffrey Y Ku Ronald P DeMatteo Marc Ladanyi Naiyer A Rizvi Michael F Berger Nadeem Riaz David B Solit Timothy A Chan Luc G T Morris

Nat Genet 2019 02 14;51(2):202-206. Epub 2019 Jan 14.

Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.

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February 2019

Obesity and cardiovascular risk in an oncology day ward population.

Authors:
David O'Reilly Lisa Prior Lucy Dooley Paula Calvert Miriam O'Connor Anne Horgan Emmet Jordan

Ir J Med Sci 2019 Aug 18;188(3):777-782. Epub 2018 Dec 18.

Department of Oncology, Waterford University Hospital, Waterford, Ireland.

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August 2019

Helicase Domain Mutations Confer Nucleotide Excision Repair Deficiency and Drive Cisplatin Sensitivity in Muscle-Invasive Bladder Cancer.

Authors:
Qiang Li Alexis W Damish Zoë Frazier David Liu Elizaveta Reznichenko Atanas Kamburov Andrew Bell Huiyong Zhao Emmet J Jordan S Paul Gao Jennifer Ma Philip H Abbosh Joaquim Bellmunt Elizabeth R Plimack Jean-Bernard Lazaro David B Solit Dean Bajorin Jonathan E Rosenberg Alan D D'Andrea Nadeem Riaz Eliezer M Van Allen Gopa Iyer Kent W Mouw

Clin Cancer Res 2019 02 6;25(3):977-988. Epub 2018 Jul 6.

Department of Radiation Oncology, Dana-Farber Cancer Institute/Brigham and Women's Hospital, Boston, Massachusetts.

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February 2019

amplification is a mechanism of acquired resistance to EGFR inhibitors identified by transposon mutagenesis and clinical genomics.

Authors:
Pang-Dian Fan Giuseppe Narzisi Anitha D Jayaprakash Elisa Venturini Nicolas Robine Peter Smibert Soren Germer Helena A Yu Emmet J Jordan Paul K Paik Yelena Y Janjigian Jamie E Chaft Lu Wang Achim A Jungbluth Sumit Middha Lee Spraggon Huan Qiao Christine M Lovly Mark G Kris Gregory J Riely Katerina Politi Harold Varmus Marc Ladanyi

Proc Natl Acad Sci U S A 2018 06 6;115(26):E6030-E6038. Epub 2018 Jun 6.

Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY 10065;

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June 2018

Comprehensive Molecular Profiling of Intrahepatic and Extrahepatic Cholangiocarcinomas: Potential Targets for Intervention.

Authors:
Maeve A Lowery Ryan Ptashkin Emmet Jordan Michael F Berger Ahmet Zehir Marinela Capanu Nancy E Kemeny Eileen M O'Reilly Imane El-Dika William R Jarnagin James J Harding Michael I D'Angelica Andrea Cercek Jaclyn F Hechtman David B Solit Nikolaus Schultz David M Hyman David S Klimstra Leonard B Saltz Ghassan K Abou-Alfa

Clin Cancer Res 2018 09 30;24(17):4154-4161. Epub 2018 May 30.

Memorial Sloan Kettering Cancer Center, New York, New York.

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September 2018

Concurrent Alterations in EGFR-Mutant Lung Cancers Associated with Resistance to EGFR Kinase Inhibitors and Characterization of MTOR as a Mediator of Resistance.

Authors:
Helena A Yu Ken Suzawa Emmet Jordan Ahmet Zehir Ai Ni Ryan Kim Mark G Kris Matthew D Hellmann Bob T Li Romel Somwar David B Solit Michael F Berger Maria Arcila Gregory J Riely Marc Ladanyi

Clin Cancer Res 2018 07 12;24(13):3108-3118. Epub 2018 Mar 12.

Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York.

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July 2018

Prospective Evaluation of Germline Alterations in Patients With Exocrine Pancreatic Neoplasms.

Authors:
Maeve A Lowery Winston Wong Emmet J Jordan Jonathan W Lee Yelena Kemel Joseph Vijai Diana Mandelker Ahmet Zehir Marinela Capanu Erin Salo-Mullen Angela G Arnold Kenneth H Yu Anna M Varghese David P Kelsen Robin Brenner Erica Kaufmann Vignesh Ravichandran Semanti Mukherjee Michael F Berger David M Hyman David S Klimstra Ghassan K Abou-Alfa Catherine Tjan Christina Covington Hannah Maynard Peter J Allen Gokce Askan Steven D Leach Christine A Iacobuzio-Donahue Mark E Robson Kenneth Offit Zsofia K Stadler Eileen M O'Reilly

J Natl Cancer Inst 2018 10;110(10):1067-1074

Department of Medicine.

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October 2018

Brain Metastases in Pancreatic Ductal Adenocarcinoma: Assessment of Molecular Genotype-Phenotype Features-An Entity With an Increasing Incidence?

Authors:
Emmet J Jordan Maeve A Lowery Olca Basturk Peter J Allen Kenneth H Yu Viviane Tabar Kathryn Beal Diane L Reidy Yoshiya Yamada Yelena Janjigian Ghassan K Abou-Alfa Eileen M O'Reilly

Clin Colorectal Cancer 2018 06 7;17(2):e315-e321. Epub 2018 Feb 7.

Gastrointestinal Oncology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY; David M. Rubenstein Center for Pancreatic Cancer Research, Memorial Sloan Kettering Cancer Center, New York, NY; Weill Cornell Medical College, New York, NY. Electronic address:

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June 2018

Case report: primary acinar cell carcinoma of the liver treated with multimodality therapy.

Authors:
Emmet J Jordan Olca Basturk Jinru Shia David S Klimstra William Alago Michael I D'Angelica Ghassan K Abou-Alfa Eileen M O'Reilly Maeve A Lowery

J Gastrointest Oncol 2017 Oct;8(5):E65-E72

Department of Gastrointestinal Oncology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.

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October 2017

Erratum: Mutational landscape of metastatic cancer revealed from prospective clinical sequencing of 10,000 patients.

Authors:
Ahmet Zehir Ryma Benayed Ronak H Shah Aijazuddin Syed Sumit Middha Hyunjae R Kim Preethi Srinivasan Jianjiong Gao Debyani Chakravarty Sean M Devlin Matthew D Hellmann David A Barron Alison M Schram Meera Hameed Snjezana Dogan Dara S Ross Jaclyn F Hechtman Deborah F DeLair JinJuan Yao Diana L Mandelker Donavan T Cheng Raghu Chandramohan Abhinita S Mohanty Ryan N Ptashkin Gowtham Jayakumaran Meera Prasad Mustafa H Syed Anoop Balakrishnan Rema Zhen Y Liu Khedoudja Nafa Laetitia Borsu Justyna Sadowska Jacklyn Casanova Ruben Bacares Iwona J Kiecka Anna Razumova Julie B Son Lisa Stewart Tessara Baldi Kerry A Mullaney Hikmat Al-Ahmadie Efsevia Vakiani Adam A Abeshouse Alexander V Penson Philip Jonsson Niedzica Camacho Matthew T Chang Helen H Won Benjamin E Gross Ritika Kundra Zachary J Heins Hsiao-Wei Chen Sarah Phillips Hongxin Zhang Jiaojiao Wang Angelica Ochoa Jonathan Wills Michael Eubank Stacy B Thomas Stuart M Gardos Dalicia N Reales Jesse Galle Robert Durany Roy Cambria Wassim Abida Andrea Cercek Darren R Feldman Mrinal M Gounder A Ari Hakimi James J Harding Gopa Iyer Yelena Y Janjigian Emmet J Jordan Ciara M Kelly Maeve A Lowery Luc G T Morris Antonio M Omuro Nitya Raj Pedram Razavi Alexander N Shoushtari Neerav Shukla Tara E Soumerai Anna M Varghese Rona Yaeger Jonathan Coleman Bernard Bochner Gregory J Riely Leonard B Saltz Howard I Scher Paul J Sabbatini Mark E Robson David S Klimstra Barry S Taylor Jose Baselga Nikolaus Schultz David M Hyman Maria E Arcila David B Solit Marc Ladanyi Michael F Berger

Nat Med 2017 08;23(8):1004

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August 2017

Real-Time Genomic Profiling of Pancreatic Ductal Adenocarcinoma: Potential Actionability and Correlation with Clinical Phenotype.

Authors:
Maeve A Lowery Emmet J Jordan Olca Basturk Ryan N Ptashkin Ahmet Zehir Michael F Berger Tanisha Leach Brian Herbst Gokce Askan Hannah Maynard Danielle Glassman Christina Covington Nikolaus Schultz Ghassan K Abou-Alfa James J Harding David S Klimstra Jaclyn F Hechtman David M Hyman Peter J Allen William R Jarnagin Vinod P Balachandran Anna M Varghese Mark A Schattner Kenneth H Yu Leonard B Saltz David B Solit Christine A Iacobuzio-Donahue Steven D Leach Eileen M O'Reilly

Clin Cancer Res 2017 Oct 28;23(20):6094-6100. Epub 2017 Jul 28.

Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York.

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October 2017

Mutational landscape of metastatic cancer revealed from prospective clinical sequencing of 10,000 patients.

Authors:
Ahmet Zehir Ryma Benayed Ronak H Shah Aijazuddin Syed Sumit Middha Hyunjae R Kim Preethi Srinivasan Jianjiong Gao Debyani Chakravarty Sean M Devlin Matthew D Hellmann David A Barron Alison M Schram Meera Hameed Snjezana Dogan Dara S Ross Jaclyn F Hechtman Deborah F DeLair JinJuan Yao Diana L Mandelker Donavan T Cheng Raghu Chandramohan Abhinita S Mohanty Ryan N Ptashkin Gowtham Jayakumaran Meera Prasad Mustafa H Syed Anoop Balakrishnan Rema Zhen Y Liu Khedoudja Nafa Laetitia Borsu Justyna Sadowska Jacklyn Casanova Ruben Bacares Iwona J Kiecka Anna Razumova Julie B Son Lisa Stewart Tessara Baldi Kerry A Mullaney Hikmat Al-Ahmadie Efsevia Vakiani Adam A Abeshouse Alexander V Penson Philip Jonsson Niedzica Camacho Matthew T Chang Helen H Won Benjamin E Gross Ritika Kundra Zachary J Heins Hsiao-Wei Chen Sarah Phillips Hongxin Zhang Jiaojiao Wang Angelica Ochoa Jonathan Wills Michael Eubank Stacy B Thomas Stuart M Gardos Dalicia N Reales Jesse Galle Robert Durany Roy Cambria Wassim Abida Andrea Cercek Darren R Feldman Mrinal M Gounder A Ari Hakimi James J Harding Gopa Iyer Yelena Y Janjigian Emmet J Jordan Ciara M Kelly Maeve A Lowery Luc G T Morris Antonio M Omuro Nitya Raj Pedram Razavi Alexander N Shoushtari Neerav Shukla Tara E Soumerai Anna M Varghese Rona Yaeger Jonathan Coleman Bernard Bochner Gregory J Riely Leonard B Saltz Howard I Scher Paul J Sabbatini Mark E Robson David S Klimstra Barry S Taylor Jose Baselga Nikolaus Schultz David M Hyman Maria E Arcila David B Solit Marc Ladanyi Michael F Berger

Nat Med 2017 Jun 8;23(6):703-713. Epub 2017 May 8.

Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York, USA.

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June 2017

Prospective Comprehensive Molecular Characterization of Lung Adenocarcinomas for Efficient Patient Matching to Approved and Emerging Therapies.

Authors:
Emmet J Jordan Hyunjae R Kim Maria E Arcila David Barron Debyani Chakravarty JianJiong Gao Matthew T Chang Andy Ni Ritika Kundra Philip Jonsson Gowtham Jayakumaran Sizhi Paul Gao Hannah C Johnsen Aphrothiti J Hanrahan Ahmet Zehir Natasha Rekhtman Michelle S Ginsberg Bob T Li Helena A Yu Paul K Paik Alexander Drilon Matthew D Hellmann Dalicia N Reales Ryma Benayed Valerie W Rusch Mark G Kris Jamie E Chaft José Baselga Barry S Taylor Nikolaus Schultz Charles M Rudin David M Hyman Michael F Berger David B Solit Marc Ladanyi Gregory J Riely

Cancer Discov 2017 06 23;7(6):596-609. Epub 2017 Mar 23.

Thoracic Oncology Service, Division of Solid Tumor Oncology, Department of Medicine, Weill Cornell Medical College, Memorial Sloan Kettering Cancer Center, New York, New York.

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June 2017

DNA Damage Response and Repair Gene Alterations Are Associated with Improved Survival in Patients with Platinum-Treated Advanced Urothelial Carcinoma.

Authors:
Min Yuen Teo Richard M Bambury Emily C Zabor Emmet Jordan Hikmat Al-Ahmadie Mariel E Boyd Nancy Bouvier Stephanie A Mullane Eugene K Cha Nitin Roper Irina Ostrovnaya David M Hyman Bernard H Bochner Maria E Arcila David B Solit Michael F Berger Dean F Bajorin Joaquim Bellmunt Gopakumar Iyer Jonathan E Rosenberg

Clin Cancer Res 2017 Jul 30;23(14):3610-3618. Epub 2017 Jan 30.

Genitourinary Oncology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York.

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July 2017

Systemic therapy for biliary cancers.

Authors:
Emmet Jordan Ghassan K Abou-Alfa Maeve A Lowery

Chin Clin Oncol 2016 Oct;5(5):65

Memorial Sloan Kettering Cancer Center, New York, NY, USA; Weill Medical College at Cornell University, New York, NY, USA.

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October 2016

The role of novel biologics in biliary cancers.

Authors:
Emmet Jordan Maria F Braghiroli Maeve A Lowery

Minerva Gastroenterol Dietol 2016 Dec 31;62(4):325-339. Epub 2016 Aug 31.

Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA -

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December 2016