Emmanuelle Génin

Emmanuelle Génin

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Emmanuelle Génin

Publications by authors named "Emmanuelle Génin"

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Correction: Whole exome sequencing study identifies novel rare and common Alzheimer's-Associated variants involved in immune response and transcriptional regulation.

Authors:
Joshua C Bis Xueqiu Jian Brian W Kunkle Yuning Chen Kara L Hamilton-Nelson William S Bush William J Salerno Daniel Lancour Yiyi Ma Alan E Renton Edoardo Marcora John J Farrell Yi Zhao Liming Qu Shahzad Ahmad Najaf Amin Philippe Amouyel Gary W Beecham Jennifer E Below Dominique Campion Laura Cantwell Camille Charbonnier Jaeyoon Chung Paul K Crane Carlos Cruchaga L Adrienne Cupples Jean-François Dartigues Stéphanie Debette Jean-François Deleuze Lucinda Fulton Stacey B Gabriel Emmanuelle Genin Richard A Gibbs Alison Goate Benjamin Grenier-Boley Namrata Gupta Jonathan L Haines Aki S Havulinna Seppo Helisalmi Mikko Hiltunen Daniel P Howrigan M Arfan Ikram Jaakko Kaprio Jan Konrad Amanda Kuzma Eric S Lander Mark Lathrop Terho Lehtimäki Honghuang Lin Kari Mattila Richard Mayeux Donna M Muzny Waleed Nasser Benjamin Neale Kwangsik Nho Gaël Nicolas Devanshi Patel Margaret A Pericak-Vance Markus Perola Bruce M Psaty Olivier Quenez Farid Rajabli Richard Redon Christiane Reitz Anne M Remes Veikko Salomaa Chloe Sarnowski Helena Schmidt Michael Schmidt Reinhold Schmidt Hilkka Soininen Timothy A Thornton Giuseppe Tosto Christophe Tzourio Sven J van der Lee Cornelia M van Duijn Otto Valladares Badri Vardarajan Li-San Wang Weixin Wang Ellen Wijsman Richard K Wilson Daniela Witten Kim C Worley Xiaoling Zhang Celine Bellenguez Jean-Charles Lambert Mitja I Kurki Aarno Palotie Mark Daly Eric Boerwinkle Kathryn L Lunetta Anita L Destefano Josée Dupuis Eden R Martin Gerard D Schellenberg Sudha Seshadri Adam C Naj Myriam Fornage Lindsay A Farrer

Mol Psychiatry 2019 Oct 21. Epub 2019 Oct 21.

Departments of Biostatistics, Boston University School of Public Health, Boston, MA, USA.

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http://dx.doi.org/10.1038/s41380-019-0529-7DOI Listing
October 2019

Rare variant association testing for multicategory phenotype.

Genet Epidemiol 2019 09 13;43(6):646-656. Epub 2019 May 13.

Univ Brest, Inserm, EFS, UMR 1078, GGB, Brest, France.

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http://dx.doi.org/10.1002/gepi.22210DOI Listing
September 2019

Blood transcriptomic biomarker as a surrogate of ischemic brain gene expression.

Ann Clin Transl Neurol 2019 Sep 10;6(9):1681-1695. Epub 2019 Aug 10.

UMR 1078 Genetics, Functional Genomics and Biotechnology, Inserm, Université de Brest, EFS, CHU de Brest, Brest, France.

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http://dx.doi.org/10.1002/acn3.50861DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6764628PMC
September 2019

Missing heritability of complex diseases: case solved?

Hum Genet 2019 Jun 4. Epub 2019 Jun 4.

Inserm, Univ Brest, EFS, CHU Brest, UMR 1078, GGB (Génétique, Génomique fonctionnelle et Biotechnologies), Faculté de Médecine, Bâtiment E-IBRBS 2ieme étage, 22 avenue Camille Desmoulins, 29200, Brest Cedex 3, France.

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http://dx.doi.org/10.1007/s00439-019-02034-4DOI Listing
June 2019

Genetics and postsurgical neuropathic pain: An ancillary study of a multicentre survey.

Eur J Anaesthesiol 2019 05;36(5):342-350

From the AP-HP, Génétique médicale, Hôpital Necker-Enfants Malades (PB), INSERM, UMR1163, Paris (PB), INSERM, UMR1078 (EG), CHU Brest, EFS (EG), Université de Brest, Brest (EG), HELIXIO, Groupe Hybrigenics, Saint-Beauzire (BJ), CHU Clermont-Ferrand, Centre de Pharmacologie Clinique (C. Dubray, C. Dualé), INSERM, CIC1405 & UMR1107 (C. Dubray, C. Dualé), Université Clermont Auvergne, Clermont-Ferrand, France (C. Dubray).

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http://dx.doi.org/10.1097/EJA.0000000000000986DOI Listing
May 2019

Sensitive Skin: Lessons From Transcriptomic Studies.

Front Med (Lausanne) 2019 28;6:115. Epub 2019 May 28.

LIEN, F-29200, Univ Brest, Brest, France.

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http://dx.doi.org/10.3389/fmed.2019.00115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6546803PMC
May 2019

Proliferation of hippocampal progenitors relies on p27-dependent regulation of Cdk6 kinase activity.

Cell Mol Life Sci 2018 Oct 4;75(20):3817-3827. Epub 2018 May 4.

Laboratory of Developmental Neurobiology, GIGA-Neurosciences, Quartier Hôpital, University of Liège, Avenue Hippocrate 15, B36 +1, 4000, Liège, Belgium.

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http://dx.doi.org/10.1007/s00018-018-2832-xDOI Listing
October 2018

Principals about principal components in statistical genetics.

Brief Bioinform 2018 Sep 14. Epub 2018 Sep 14.

University of Liège working on Systems Genetics.

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http://dx.doi.org/10.1093/bib/bby081DOI Listing
September 2018

Whole exome sequencing study identifies novel rare and common Alzheimer's-Associated variants involved in immune response and transcriptional regulation.

Authors:
Joshua C Bis Xueqiu Jian Brian W Kunkle Yuning Chen Kara L Hamilton-Nelson William S Bush William J Salerno Daniel Lancour Yiyi Ma Alan E Renton Edoardo Marcora John J Farrell Yi Zhao Liming Qu Shahzad Ahmad Najaf Amin Philippe Amouyel Gary W Beecham Jennifer E Below Dominique Campion Laura Cantwell Camille Charbonnier Jaeyoon Chung Paul K Crane Carlos Cruchaga L Adrienne Cupples Jean-François Dartigues Stéphanie Debette Jean-François Deleuze Lucinda Fulton Stacey B Gabriel Emmanuelle Genin Richard A Gibbs Alison Goate Benjamin Grenier-Boley Namrata Gupta Jonathan L Haines Aki S Havulinna Seppo Helisalmi Mikko Hiltunen Daniel P Howrigan M Arfan Ikram Jaakko Kaprio Jan Konrad Amanda Kuzma Eric S Lander Mark Lathrop Terho Lehtimäki Honghuang Lin Kari Mattila Richard Mayeux Donna M Muzny Waleed Nasser Benjamin Neale Kwangsik Nho Gaël Nicolas Devanshi Patel Margaret A Pericak-Vance Markus Perola Bruce M Psaty Olivier Quenez Farid Rajabli Richard Redon Christiane Reitz Anne M Remes Veikko Salomaa Chloe Sarnowski Helena Schmidt Michael Schmidt Reinhold Schmidt Hilkka Soininen Timothy A Thornton Giuseppe Tosto Christophe Tzourio Sven J van der Lee Cornelia M van Duijn Otto Valladares Badri Vardarajan Li-San Wang Weixin Wang Ellen Wijsman Richard K Wilson Daniela Witten Kim C Worley Xiaoling Zhang Celine Bellenguez Jean-Charles Lambert Mitja I Kurki Aarno Palotie Mark Daly Eric Boerwinkle Kathryn L Lunetta Anita L Destefano Josée Dupuis Eden R Martin Gerard D Schellenberg Sudha Seshadri Adam C Naj Myriam Fornage Lindsay A Farrer

Mol Psychiatry 2018 Aug 14. Epub 2018 Aug 14.

Departments of Biostatistics, Boston University School of Public Health, Boston, MA, USA.

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http://dx.doi.org/10.1038/s41380-018-0112-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6375806PMC
August 2018

Factors influencing the age at onset in familial frontotemporal lobar dementia: Important weight of genetics.

Neurol Genet 2017 Dec 13;3(6):e203. Epub 2017 Dec 13.

INSERM U1127 (M.B., A.C., P.C., C.F., D.R., A.B., I.L.B.), CNRS UMR 7225, UPMC Université Paris 06 UMR S1127, Sorbonne Université Institut du Cerveau et de la Moelle épinière, ICM; Ecole Pratique des Hautes Etudes-EPHE (A.C.), PSL Research University; Institute of Memory and Alzheimer's Disease (IM2A) (M.H., P.C., D.R., I.L.B.), Centre of Excellence of Neurodegenerative Disease (CoEN), ICM, APHP Department of Neurology, Hopital Pitié-Salpêtrière, University Paris 6; Unité Fonctionnelle de Neurogénétique Moléculaire et Cellulaire (F.C., K.L.), Département de Génétique et Cytogénétique, AP-HP, Hôpitaux Universitaires La Pitié Salpêtrière-Charles Foix, Paris, France; Carlo Besta Neurological Institute (P.C.), IRCCS Foundation, Milano, Italy; Assistance Publique-Hôpitaux de Paris (D.R., I.L.B.), Hôpital Pitié-Salpêtrière, Centre de référence Démences Rares, Paris, France; Université de Lille (F.P.), Inserm U1171, CHU Lille, Labex DistAlz, LiCEND, France; Department of Neurology (D.H.), University Hospital, Rouen, France; Département de Neurologie (J.P.), CHU Toulouse, Equipe TONIC, INSERM, Place du Dr Baylac, France; INSERM (E.G.), UMR1078, CHU Brest, Université Bretagne Occidentale, France; and Institut de Recherche pour le Développement (IRD) (A.S.), UMR216-MERIT, Paris, France.

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http://dx.doi.org/10.1212/NXG.0000000000000203DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5730818PMC
December 2017

DCTN4 as a modifier of chronic Pseudomonas aeruginosa infection in cystic fibrosis.

Clin Respir J 2016 Nov 15;10(6):777-783. Epub 2015 Apr 15.

AP-HP, Laboratoire de Biochimie et Génétique Moléculaire, Groupe Universitaire Paris Centre, Paris, France.

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http://doi.wiley.com/10.1111/crj.12288
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http://dx.doi.org/10.1111/crj.12288DOI Listing
November 2016

Highlighting the impact of cascade carrier testing in cystic fibrosis families.

J Cyst Fibros 2016 07 22;15(4):452-9. Epub 2016 Mar 22.

Inserm, UMR 1078, Brest, France; Univ. Brest, Brest, France; Etablissement Français du Sang-Bretagne, Brest, France. Electronic address:

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http://dx.doi.org/10.1016/j.jcf.2016.02.013DOI Listing
July 2016

ABCA7 rare variants and Alzheimer disease risk.

Neurology 2016 Jun 1;86(23):2134-7. Epub 2016 Apr 1.

From INSERM (K.L.G., G.N., O.Q., C.C., D.W., S.R., A.C.R., A.R.-L., T.F., D.H., D.C.), U1079, IRIB, University of Rouen, Normandy University; Normandy Centre for Genomic Medicine and Personalized Medicine (K.L.G., G.N., O.Q., C.C., D.W., S.R., A.-C.R., A.R.-L., T.F., D.H., D.C.), Rouen; Department of Genetics (G.N., T.F., D.H.), CNR-MAJ (G.N., O.Q., C.C., D.W., S.R., A.-C.R., F.P., A.R.-S., D.H., D.C.), and Department of Neurology (D.W., D.H.), Rouen University Hospital; INSERM (C.B., B.G.-B., P.A., J.-C.L.), U1167, Lille; Institut Pasteur de Lille (C.B., B.G.-B., P.A., J.-C.L.); Université Lille-Nord de France (C.B., B.G.-B., P.A., J.-C.L.); Centre National de Génotypage (D.B., J.-G.G., R.O., A.B., V.M., J.-F.Deleuze.), Institut de Génomique, CEA, Evry; Fondation Jean Dausset (J.-F.Deleuze.), Centre d'Etudes du Polymorphisme Humain, Paris, France; McGill University and Génome Québec Innovation Centre (H.M.M., G.B., M.L.), Montréal, Canada; INSERM (R.R.), UMR 1087, l'Institut du Thorax, CHU Nantes; CNRS (R.R.), UMR 6291, Université de Nantes; INSERM (L.L., J.-F.Dartigues.), U897, Bordeaux; University of Bordeaux (L.L., J.-F.Dartigues.); Department of Neurology (F.P., A.R.S.), Lille University Hospital; INSERM (E.G.), UMR1078, CHU Brest, Université Bretagne Occidentale, Brest; and Department of Research (D.C.), Rouvray Psychiatric Hospital, Sotteville-lès-Rouen, France.

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http://dx.doi.org/10.1212/WNL.0000000000002627DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4898320PMC
June 2016

Accuracy of heritability estimations in presence of hidden population stratification.

Sci Rep 2016 05 25;6:26471. Epub 2016 May 25.

CESP, Inserm, Univ. Paris-Sud, Université Paris-Saclay, Villejuif, France.

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http://dx.doi.org/10.1038/srep26471DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4879529PMC
May 2016

Integration of Omics Data in Genetic Epidemiology.

Hum Hered 2015 28;79(3-4):109-10. Epub 2015 Jul 28.

INSERM UMR1078, CHU Brest, Université Bretagne Occidentale, Brest, France.

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http://search.proquest.com/openview/8f928e857ec313f9daabd485
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http://dx.doi.org/10.1159/000382041DOI Listing
April 2016

Relationship inference from the genetic data on parents or offspring: A comparative study.

Theor Popul Biol 2016 Feb 30;107:31-8. Epub 2015 Sep 30.

Inserm, U946, Genetic Variation and Human Diseases Lab, Paris, France; Université Paris Diderot, Sorbonne Paris Cité, Institut Universitaire d'Hématologie, UMR 946, Paris, France. Electronic address:

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http://dx.doi.org/10.1016/j.tpb.2015.09.002DOI Listing
February 2016

High level of inbreeding in final phase of 1000 Genomes Project.

Sci Rep 2015 Dec 2;5:17453. Epub 2015 Dec 2.

INSERM, Genetic variability and human diseases, UMR 946, F-75010 Paris, France.

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http://dx.doi.org/10.1038/srep17453DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4667178PMC
December 2015

CHCHD10 mutations are not a common cause of SMN1-negative type III/IV spinal motor atrophy.

Ann Neurol 2015 Nov 31;78(5):831. Epub 2015 Aug 31.

Department of Medical Genetics, National Center for Mitochondrial Diseases, Nice Teaching Hospital, Nice, France.

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http://dx.doi.org/10.1002/ana.24464DOI Listing
November 2015

Identification of a functional PRSS1 promoter variant in linkage disequilibrium with the chronic pancreatitis-protecting rs10273639.

Gut 2015 Nov 5;64(11):1837-8. Epub 2015 Aug 5.

Institut National de la Santé et de la Recherche Médicale (INSERM), Brest, France Faculté de Médecine et des Sciences de la Santé, Université de Bretagne Occidentale (UBO), Brest, France Etablissement Français du sang (EFS)-Bretagne, Brest, France Laboratoire de Génétique Moléculaire et d'Histocompatibilité, Centre Hospitalier Régional Universitaire (CHRU) Brest, Hôpital Morvan, Brest, France.

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http://gut.bmj.com/content/64/11/1837.full.pdf
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http://gut.bmj.com/lookup/doi/10.1136/gutjnl-2015-310254
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http://dx.doi.org/10.1136/gutjnl-2015-310254DOI Listing
November 2015

Poor survival in rheumatoid arthritis associated with bronchiectasis: a family-based cohort study.

PLoS One 2014 13;9(10):e110066. Epub 2014 Oct 13.

Department of Respiratory Diseases, Hôpital Cochin, Assistance Publique-Hôpitaux de Paris, Université Paris Descartes, Paris, France.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0110066PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4195708PMC
September 2015

The missing heritability paradigm: a dramatic resurgence of the GIGO syndrome in genetics.

Hum Hered 2015 6;79(1):1-4. Epub 2015 Feb 6.

INSERM UMR1078, CHU Brest, Université Bretagne Occidentale, Brest, France.

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http://dx.doi.org/10.1159/000370327DOI Listing
September 2015

Letter to the Editor on a paper by Hsiao C-T, Tsai P-C, Liao Y-C, Lee Y-C, Soong B-W. C9ORF72 repeat expansion is not a significant cause of late-onset cerebellar ataxia syndrome. J Neurol Sci 2014;347:322-324.

J Neurol Sci 2015 Apr 20;351(1-2):196-197. Epub 2015 Feb 20.

IRCAN, UMR CNRS 7284/INSERM U1081/UNS, School of Medicine, Nice Sophia-Antipolis University, France; Department of Medical Genetics, National Centre for Mitochondrial Diseases, Nice Teaching Hospital, France. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S0022510X150009
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http://dx.doi.org/10.1016/j.jns.2015.02.025DOI Listing
April 2015

Inbreeding coefficient estimation with dense SNP data: comparison of strategies and application to HapMap III.

Hum Hered 2014 29;77(1-4):49-62. Epub 2014 Jul 29.

Genetic Variability and Human Diseases, Inserm, U946, Paris, France.

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http://dx.doi.org/10.1159/000358224DOI Listing
March 2015

Genome-wide association study identifies TF as a significant modifier gene of iron metabolism in HFE hemochromatosis.

J Hepatol 2015 Mar 18;62(3):664-72. Epub 2014 Oct 18.

CHU de Rennes, Liver Unit and French Reference Centre for Rare Iron Overload Diseases of Genetic Origin, Rennes, France; INSERM, UMR 991, Equipe Fer et Foie, Rennes, France; INSERM, Centre of Clinical Investigation 0203, CHU de Rennes, Rennes, France.

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http://dx.doi.org/10.1016/j.jhep.2014.10.017DOI Listing
March 2015

Advantage of using allele-specific copy numbers when testing for association in regions with common copy number variants.

PLoS One 2013 10;8(9):e75350. Epub 2013 Sep 10.

Inserm UMR-S946, Univ. Paris Diderot, Institut Universitaire d'Hématologie, Paris, France ; Genetic and Molecular Epidemiology Group, Spanish National Cancer Research Centre (CNIO), Madrid, Spain.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0075350PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3769257PMC
February 2015

Screening of CHCHD10 in a French cohort confirms the involvement of this gene in frontotemporal dementia with amyotrophic lateral sclerosis patients.

Neurobiol Aging 2014 Dec 24;35(12):2884.e1-2884.e4. Epub 2014 Jul 24.

IRCAN, UMR CNRS 7284/INSERM U1081/UNS, School of Medicine, Nice Sophia-Antipolis University, Nice, France; Department of Medical Genetics, National Centre for Mitochondrial Diseases, Nice Teaching Hospital, Nice, France. Electronic address:

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http://dx.doi.org/10.1016/j.neurobiolaging.2014.07.022DOI Listing
December 2014

How important are rare variants in common disease?

Brief Funct Genomics 2014 Sep 8;13(5):353-61. Epub 2014 Jul 8.

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http://dx.doi.org/10.1093/bfgp/elu025DOI Listing
September 2014

Haploinsufficiency of Dmxl2, encoding a synaptic protein, causes infertility associated with a loss of GnRH neurons in mouse.

PLoS Biol 2014 Sep 23;12(9):e1001952. Epub 2014 Sep 23.

Inserm, U1141, Paris, France; Université Paris Diderot, Sorbonne Paris Cité, Hôpital Robert Debré, Paris, France; AP-HP, Laboratoire de Biochimie, Hôpital Robert Debré, Paris, France.

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http://dx.doi.org/10.1371/journal.pbio.1001952DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4172557PMC
September 2014

FSuite: exploiting inbreeding in dense SNP chip and exome data.

Bioinformatics 2014 Jul 14;30(13):1940-1. Epub 2014 Mar 14.

Inserm, U946, Genetic variability and human diseases, Paris, 75010, Université Paris Sud, Kremlin-Bicêtre, 94270, Fondation Jean Dausset CEPH, Paris, 75010, Université Paris-Diderot, UMR 946, Institut Universitaire d'Hématologie, Paris, 75475, Inserm, U1078, Génétique, Génomique fonctionnelle et Biotechnologies, Brest, 29218 and Centre Hospitalier Régional Universitaire de Brest, Brest, 29200, France Inserm, U946, Genetic variability and human diseases, Paris, 75010, Université Paris Sud, Kremlin-Bicêtre, 94270, Fondation Jean Dausset CEPH, Paris, 75010, Université Paris-Diderot, UMR 946, Institut Universitaire d'Hématologie, Paris, 75475, Inserm, U1078, Génétique, Génomique fonctionnelle et Biotechnologies, Brest, 29218 and Centre Hospitalier Régional Universitaire de Brest, Brest, 29200, France.

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http://dx.doi.org/10.1093/bioinformatics/btu149DOI Listing
July 2014

Molecular reclassification of Crohn's disease: a cautionary note on population stratification.

PLoS One 2013 17;8(10):e77720. Epub 2013 Oct 17.

UMR843, INSERM, Paris, France ; Bioinformatics and Modeling, GIGA-R, University of Liège, Liège, Belgium.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0077720PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3798408PMC
June 2014

Concise review: forkhead pathway in the control of adult neurogenesis.

Stem Cells 2014 Jun;32(6):1398-407

GIGA-Neurosciences, Developmental Neurobiology Unit, University of Liège, Liège, Belgium.

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http://doi.wiley.com/10.1002/stem.1673
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http://dx.doi.org/10.1002/stem.1673DOI Listing
June 2014

Could inbred cases identified in GWAS data succeed in detecting rare recessive variants where affected sib-pairs have failed?

Hum Hered 2012 11;74(3-4):142-52. Epub 2013 Apr 11.

Inserm UMR-946, Genetic Variability and Human Diseases, Paris, France.

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http://dx.doi.org/10.1159/000346790DOI Listing
October 2013

Positive selection in the chromosome 16 VKORC1 genomic region has contributed to the variability of anticoagulant response in humans.

PLoS One 2012 28;7(12):e53049. Epub 2012 Dec 28.

Inserm UMRS-946, Genetic Variability and Human Diseases, Institut Universitaire d'Hématologie, Université Paris Diderot, Paris, France.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0053049PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3532425PMC
July 2013

Comparative power of family-based association strategies to detect disease-causing variants under two-locus models.

Genet Epidemiol 2012 Dec 9;36(8):848-55. Epub 2012 Aug 9.

INSERM, UMR-S946, Fondation Jean Dausset-CEPH, Paris, France; Univ Paris-Diderot, PRES Sorbonne Paris Cité, Institut Universitaire d'Hématologie, UMR-S946, Paris, France.

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http://doi.wiley.com/10.1002/gepi.21672
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http://dx.doi.org/10.1002/gepi.21672DOI Listing
December 2012

Incidence of Abcd1 level on the induction of cell death and organelle dysfunctions triggered by very long chain fatty acids and TNF-α on oligodendrocytes and astrocytes.

Neurotoxicology 2012 Mar 25;33(2):212-28. Epub 2011 Oct 25.

Centre de Recherche INSERM 866 'Lipides, Nutrition, Cancer', Université de Bourgogne, Equipe 'Biochimie du Peroxysome, Inflammation et Métabolisme Lipidique', Dijon, France.

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http://linkinghub.elsevier.com/retrieve/pii/S0161813X1100192
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http://dx.doi.org/10.1016/j.neuro.2011.10.007DOI Listing
March 2012

No replication of genetic association between candidate polymorphisms and Alzheimer's disease.

Neurobiol Aging 2011 Aug 3;32(8):1443-51. Epub 2009 Nov 3.

Biological Sciences Department, sanofi-aventis Recherche et Développement, Centre de Génétique humaine, 91057 Evry, France.

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http://dx.doi.org/10.1016/j.neurobiolaging.2009.09.004DOI Listing
August 2011

Mutations of the cystic fibrosis gene in patients with bronchiectasis associated with rheumatoid arthritis.

Ann Rheum Dis 2011 Apr 3;70(4):653-9. Epub 2010 Dec 3.

Center for Rare Systemic Auto-immune Diseases, Department of Rheumatology, Centre Hospitalier du Mans, 194 avenue Rubillard, 72000 Le Mans, France.

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http://ard.bmj.com/content/70/4/653.full.pdf
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http://ard.bmj.com/cgi/doi/10.1136/ard.2010.142760
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http://dx.doi.org/10.1136/ard.2010.142760DOI Listing
April 2011

Genetic association and gene-environment interaction: a new method for overcoming the lack of exposure information in controls.

Am J Epidemiol 2011 Jan 17;173(2):225-35. Epub 2010 Nov 17.

Université Paris-Sud, Le Kremlin Bicêtre, France.

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http://dx.doi.org/10.1093/aje/kwq352DOI Listing
January 2011

A mixture model approach to multiple testing for the genetic analysis of gene expression.

BMC Proc 2007 18;1 Suppl 1:S141. Epub 2007 Dec 18.

JE 2492 Universite Paris-Sud, Hôpital Paul Brousse - Batiment 15/16, 16 Avenue Paul Vaillant Couturier, Villejuif CEDEX 94807, France.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2367480PMC
http://dx.doi.org/10.1186/1753-6561-1-s1-s141DOI Listing
December 2009

Dealing with missing phase and missing data in phylogeny-based analysis.

BMC Proc 2007 18;1 Suppl 1:S22. Epub 2007 Dec 18.

UMR 5145 - Génétique des Populations Humaines - CNRS MNH, Université Paris VII, 17 Place du Trocadero, Paris, 75016 France.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2367603PMC
http://dx.doi.org/10.1186/1753-6561-1-s1-s22DOI Listing
December 2009

Efficiency of multiple imputation to test for association in the presence of missing data.

BMC Proc 2007 18;1 Suppl 1:S24. Epub 2007 Dec 18.

Universite Paris-Sud UMR-S535, Villejuif, 94817 France.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2367517PMC
http://dx.doi.org/10.1186/1753-6561-1-s1-s24DOI Listing
December 2009

Induction of the adrenoleukodystrophy-related gene (ABCD2) by thyromimetics.

J Steroid Biochem Mol Biol 2009 Aug 3;116(1-2):37-43. Epub 2009 May 3.

INSERM, U866, Dijon, F-21000, France.

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http://dx.doi.org/10.1016/j.jsbmb.2009.04.006DOI Listing
August 2009

Identifying modifier genes of monogenic disease: strategies and difficulties.

Hum Genet 2008 Nov 11;124(4):357-68. Epub 2008 Sep 11.

Inserm UMR-S535, 94817, Villejuif, France.

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http://dx.doi.org/10.1007/s00439-008-0560-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2911473PMC
November 2008

Cystic fibrosis carrier frequency and estimated prevalence of the disease in Morocco.

J Cyst Fibros 2008 Sep 1;7(5):440-3. Epub 2008 Feb 1.

Service de Biochimie et Génétique, AP-HP et INSERM U841 équipe 11, groupe hospitalier Henri Mondor-Albert Chenevier, 94010 Créteil, France.

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http://dx.doi.org/10.1016/j.jcf.2007.12.006DOI Listing
September 2008

Hereditary hemorrhagic telangiectasia: evidence for regional founder effects of ACVRL1 mutations in French and Italian patients.

Eur J Hum Genet 2008 Jun 20;16(6):742-9. Epub 2008 Feb 20.

Service de Génétique Moléculaire et Clinique, Hôpital Edouard Herriot, Université de Lyon, Université Lyon 1, 5 Place d'Arsonval, Lyon, France.

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http://dx.doi.org/10.1038/ejhg.2008.3DOI Listing
June 2008

Selecting predictive markers for pharmacogenetic traits: tagging vs. data-mining approaches.

Hum Hered 2008 28;66(1):10-8. Epub 2008 Jan 28.

INSERM, UMR-S0535, Villejuif, France.

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http://dx.doi.org/10.1159/000114161DOI Listing
April 2008

Estimating the age of CFTR mutations predominantly found in Brittany (Western France).

J Cyst Fibros 2008 Mar 6;7(2):168-73. Epub 2007 Sep 6.

Inserm, U613, Génétique Moléculaire et Génétique Epidémiologique, Etablissement Français du Sang, 46 rue Félix Le Dantec, BP62025, F-29220, Brest, France.

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http://dx.doi.org/10.1016/j.jcf.2007.07.009DOI Listing
March 2008

Familial Mediterranean Fever in Lebanon: founder effects for different MEFV mutations.

Ann Hum Genet 2008 Jan 16;72(Pt 1):41-7. Epub 2007 Aug 16.

Unité de Génétique Médicale, Faculté de médecine, Université Saint-Joseph, Beirut, Lebanon.

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http://dx.doi.org/10.1111/j.1469-1809.2007.00386.xDOI Listing
January 2008

Dealing with missing data in family-based association studies: a multiple imputation approach.

Hum Hered 2007 7;63(3-4):229-38. Epub 2007 Mar 7.

Université Paris-Sud, UMR-S535, Villejuif, France.

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http://dx.doi.org/10.1159/000100481DOI Listing
June 2007

Are genome-wide association studies all that we need to dissect the genetic component of complex human diseases?

Eur J Hum Genet 2007 Mar 13;15(3):260-3. Epub 2006 Dec 13.

1INSERM U535, University Paris Sud, Villejuif F-94817, France.

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http://dx.doi.org/10.1038/sj.ejhg.5201753DOI Listing
March 2007