Emmanuelle di Tomaso

Emmanuelle di Tomaso

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Emmanuelle di Tomaso

Emmanuelle di Tomaso

Publications by authors named "Emmanuelle di Tomaso"

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50Publications

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Phase Ib study of Buparlisib plus Trastuzumab in patients with HER2-positive advanced or metastatic breast cancer that has progressed on Trastuzumab-based therapy.

Clin Cancer Res 2014 Apr 27;20(7):1935-45. Epub 2014 Jan 27.

Authors' Affiliations: Medical Oncology Department, Vall d'Hebron University Hospital, Vall d'Hebron Institute of Oncology (VHIO), Barcelona, Spain; Catalan Institute of Oncology, Barcelona, Spain; Sarah Cannon Research Institute, Nashville, Tennessee; Novartis Pharmaceuticals, East Hanover, NJ; Novartis Pharmaceuticals, Florham Park, New Jersy; C.H.U. Sart-Tilman, Liege; Oncologisch Centrum AZ-St. Augustinus Oncology, Antwerp, Belgium; Novartis Pharma AG, Basel, Switzerland; Novartis Oncology, Paris, France; Memorial Sloan-Kettering Cancer Centre, New York, New York; Highlands Oncology Group, Fayetteville, Arkansas; and Novartis Institutes for BioMedical Research, Cambridge, Massachusetts.

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http://dx.doi.org/10.1158/1078-0432.CCR-13-1070DOI Listing
April 2014

A genetic mouse model of invasive endometrial cancer driven by concurrent loss of Pten and Lkb1 Is highly responsive to mTOR inhibition.

Cancer Res 2014 Jan 9;74(1):15-23. Epub 2013 Dec 9.

Authors' Affiliations: Department of Cancer Biology; Division of Women's Cancers, Department of Medical Oncology, Dana-Farber Cancer Institute; Departments of Biological Chemistry and Molecular Pharmacology and Systems Biology; Rodent Histopathology Core, DF/HCC, Harvard Medical School; Department of Surgery, Brigham and Women's Hospital; Division of Signal Transduction, Beth Israel Deaconess Medical Center, Boston; Novartis Institutes for Biomedical Research, Cambridge, Massacheusetts; Department of System Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas; and Novartis Institutes for Biomedical Research, Oncology Disease Area, Novartis Pharma AG, Basel, Switzerland.

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http://dx.doi.org/10.1158/0008-5472.CAN-13-0544DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3982380PMC
January 2014

Merlin/NF2 regulates angiogenesis in schwannomas through a Rac1/semaphorin 3F-dependent mechanism.

Neoplasia 2012 Feb;14(2):84-94

The Steele Lab of Tumor Biology, Department of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA; Center for Neurologic Diseases, Brigham and Women’s Hospital and Harvard Medical School, Harvard Institutes of Medicine, Boston, MA 02115, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3306254PMC
http://dx.doi.org/10.1593/neo.111600DOI Listing
February 2012

Exploratory analysis of early toxicity of sunitinib in advanced hepatocellular carcinoma patients: kinetics and potential biomarker value.

Clin Cancer Res 2011 Feb 15;17(4):918-27. Epub 2010 Sep 15.

Division of Hematology/Oncology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02114, USA.

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http://dx.doi.org/10.1158/1078-0432.CCR-10-0515DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3023846PMC
February 2011

Anti-vascular endothelial growth factor therapies as a novel therapeutic approach to treating neurofibromatosis-related tumors.

Cancer Res 2010 May 20;70(9):3483-93. Epub 2010 Apr 20.

Department of Radiation Oncology, Steele Laboratory, Massachusetts General Hospital Cancer Center, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-09-3107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4785015PMC
May 2010

PDGF-C induces maturation of blood vessels in a model of glioblastoma and attenuates the response to anti-VEGF treatment.

PLoS One 2009 8;4(4):e5123. Epub 2009 Apr 8.

E.L. Steele Laboratory for Tumor Biology, Department of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0005123PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2662415PMC
July 2009

Edema control by cediranib, a vascular endothelial growth factor receptor-targeted kinase inhibitor, prolongs survival despite persistent brain tumor growth in mice.

J Clin Oncol 2009 May 30;27(15):2542-52. Epub 2009 Mar 30.

Edwin L Steele Laboratory, Department of Radiation Oncology, Stephen E and Catherine Pappas Center for Neuro-Oncology, and AA Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.

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http://dx.doi.org/10.1200/JCO.2008.19.9356DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2739611PMC
May 2009

Antiangiogenic agents for the treatment of glioblastoma.

Expert Opin Investig Drugs 2007 Dec;16(12):1895-908

1Massachusetts General Hospital Cancer Center and Harvard Medical School, Department of Neurology, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1517/13543784.16.12.1895DOI Listing
December 2007

Angiogenesis in brain tumours.

Nat Rev Neurosci 2007 Aug;8(8):610-22

Department of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School, 100 Blossom Street, Boston, Massachusetts 02114, USA.

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http://www.nature.com/articles/nrn2175
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http://dx.doi.org/10.1038/nrn2175DOI Listing
August 2007

Robust 3-D modeling of vasculature imagery using superellipsoids.

IEEE Trans Med Imaging 2007 Feb;26(2):223-37

Department of Electrical, Computer and Systems Engineering, Rensselaer Polytechnic Institute, Troy, NY 12180, USA.

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http://dx.doi.org/10.1109/TMI.2006.889722DOI Listing
February 2007

Differential CD146 expression on circulating versus tissue endothelial cells in rectal cancer patients: implications for circulating endothelial and progenitor cells as biomarkers for antiangiogenic therapy.

J Clin Oncol 2006 Mar;24(9):1449-53

Steele Laboratory for Tumor Biology, Department of Radiation Oncology and Center for Regenerative Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA.

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http://dx.doi.org/10.1200/JCO.2005.04.2861DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2718681PMC
March 2006

Mosaic tumor vessels: cellular basis and ultrastructure of focal regions lacking endothelial cell markers.

Cancer Res 2005 Jul;65(13):5740-9

Steele Laboratory for Tumor Biology, Department of Radiation Oncology, Harvard Medical School and Massachusetts General Hospital, Boston, Massachusetts 02114, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-04-4552DOI Listing
July 2005

Pathology: cancer cells compress intratumour vessels.

Nature 2004 Feb;427(6976):695

Edwin L. Steele Laboratory, Department of Radiation Oncology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA.

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http://dx.doi.org/10.1038/427695aDOI Listing
February 2004

Responses to antiangiogenesis treatment of spontaneous autochthonous tumors and their isografts.

Cancer Res 2003 Feb;63(4):747-51

Department of Radiation Oncology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA.

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February 2003

Lymphatic metastasis in the absence of functional intratumor lymphatics.

Science 2002 Jun 25;296(5574):1883-6. Epub 2002 Apr 25.

E. L. Steele Laboratory, Department of Radiation Oncology, Massachusetts General Hospital, Harvard Medical School, 100 Blossom Street, Boston, MA 02114, USA.

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http://www.sciencemag.org/cgi/doi/10.1126/science.1071420
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http://dx.doi.org/10.1126/science.1071420DOI Listing
June 2002

Tumour biology: herceptin acts as an anti-angiogenic cocktail.

Nature 2002 Mar;416(6878):279-80

Edwin L. Steele Laboratory, Department of Radiation Oncology, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.

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http://www.nature.com/articles/416279b
Publisher Site
http://dx.doi.org/10.1038/416279bDOI Listing
March 2002