Publications by authors named "Emmanuel S Burgos"

17Publications

A Binary Arginine Methylation Switch on Histone H3 Arginine 2 Regulates Its Interaction with WDR5.

Biochemistry 2020 Oct 31;59(39):3696-3708. Epub 2020 Mar 31.

Department of Biochemistry, Albert Einstein College of Medicine, Bronx, New York 10461, United States.

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http://dx.doi.org/10.1021/acs.biochem.0c00035DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7529705PMC
October 2020

N-Acetylcysteine Resolves Placental Inflammatory-Vasculopathic Changes in Mice Consuming a High-Fat Diet.

Am J Pathol 2019 11 17;189(11):2246-2257. Epub 2019 Aug 17.

Department of Biochemistry, Albert Einstein College of Medicine, New York, New York; Department of Medicine, Albert Einstein College of Medicine, New York, New York; Department of Obstetrics and Gynecology and Women's Health, Albert Einstein College of Medicine, New York, New York. Electronic address:

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http://dx.doi.org/10.1016/j.ajpath.2019.07.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6892186PMC
November 2019

Sarcosine Is Uniquely Modulated by Aging and Dietary Restriction in Rodents and Humans.

Cell Rep 2018 10;25(3):663-676.e6

Department of Molecular Pharmacology, Albert Einstein College of Medicine, Bronx, NY, USA; Department of Medicine, Albert Einstein College of Medicine, Bronx, NY, USA; Institute for Aging Research, Albert Einstein College of Medicine, Bronx, NY, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2018.09.065DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6280974PMC
October 2018

A simplified characterization of -adenosyl-l-methionine-consuming enzymes with 1-Step EZ-MTase: a universal and straightforward coupled-assay for and setting.

Chem Sci 2017 Sep 27;8(9):6601-6612. Epub 2017 Jul 27.

Department of Biochemistry , Albert Einstein College of Medicine , 1300 Morris Park Avenue , Bronx , New York 10461 , USA . Email: ; Email: ; ; Tel: +1-718-430-4120 ; Tel: +1-718-430-4128.

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http://dx.doi.org/10.1039/c7sc02830jDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5676521PMC
September 2017

Active site and remote contributions to catalysis in methylthioadenosine nucleosidases.

Biochemistry 2015 Apr 3;54(15):2520-9. Epub 2015 Apr 3.

†Department of Biochemistry, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, New York 10461, United States.

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http://dx.doi.org/10.1021/bi501487wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4485437PMC
April 2015

Histone H2A and H4 N-terminal tails are positioned by the MEP50 WD repeat protein for efficient methylation by the PRMT5 arginine methyltransferase.

J Biol Chem 2015 Apr 24;290(15):9674-89. Epub 2015 Feb 24.

From the Department of Biochemistry, Albert Einstein College of Medicine of Yeshiva University, Bronx, New York 10461 and

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http://dx.doi.org/10.1074/jbc.M115.636894DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4392268PMC
April 2015

Transition-state analysis of 2-O-acetyl-ADP-ribose hydrolysis by human macrodomain 1.

ACS Chem Biol 2014 Oct 5;9(10):2255-62. Epub 2014 Aug 5.

Department of Biochemistry, Albert Einstein College of Medicine , 1300 Morris Park Avenue, Bronx, New York 10461, United States.

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http://dx.doi.org/10.1021/cb500485wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4201351PMC
October 2014

Potent inhibition of the C-P lyase nucleosidase PhnI by Immucillin-A triphosphate.

Biochemistry 2013 Oct 11;52(42):7366-8. Epub 2013 Oct 11.

Department of Chemistry, Texas A&M University , College Station, Texas 77840, United States.

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http://dx.doi.org/10.1021/bi4013287DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3838859PMC
October 2013

Recycling nicotinamide. The transition-state structure of human nicotinamide phosphoribosyltransferase.

J Am Chem Soc 2013 Mar 19;135(9):3485-93. Epub 2013 Feb 19.

Department of Biochemistry, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, New York 10461, United States.

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http://dx.doi.org/10.1021/ja310180cDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3627370PMC
March 2013

Exploring inhibition of Pdx1, a component of the PLP synthase complex of the human malaria parasite Plasmodium falciparum.

Biochem J 2013 Jan;449(1):175-87

Bernhard Nocht Institute for Tropical Medicine, Department of Biochemistry, Bernhard Nocht-Strasse 74, D-20359 Hamburg, Germany.

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http://dx.doi.org/10.1042/BJ20120925DOI Listing
January 2013

Femtomolar inhibitors bind to 5'-methylthioadenosine nucleosidases with favorable enthalpy and entropy.

Biochemistry 2012 Sep 11;51(38):7541-50. Epub 2012 Sep 11.

Department of Biochemistry, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, NY 10461, USA.

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http://dx.doi.org/10.1021/bi3009938DOI Listing
September 2012

Luciferase-based assay for adenosine: application to S-adenosyl-L-homocysteine hydrolase.

Anal Chem 2012 Apr 28;84(8):3593-8. Epub 2012 Mar 28.

Department of Biochemistry, Albert Einstein College of Medicine of Yeshiva University, Bronx, New York 10461, United States.

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http://dx.doi.org/10.1021/ac203297zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3328629PMC
April 2012

A high-affinity adenosine kinase from Anopheles gambiae.

Biochemistry 2011 Mar 15;50(11):1885-93. Epub 2011 Feb 15.

Department of Biochemistry, Albert Einstein College of Medicine, Yeshiva University, Bronx, New York 10461, United States.

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http://dx.doi.org/10.1021/bi101921wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3059358PMC
March 2011

A phosphoenzyme mimic, overlapping catalytic sites and reaction coordinate motion for human NAMPT.

Proc Natl Acad Sci U S A 2009 Aug 4;106(33):13748-53. Epub 2009 Aug 4.

Department of Biochemistry, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, NY 10461, USA.

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http://dx.doi.org/10.1073/pnas.0903898106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2728965PMC
August 2009

Weak coupling of ATP hydrolysis to the chemical equilibrium of human nicotinamide phosphoribosyltransferase.

Biochemistry 2008 Oct 30;47(42):11086-96. Epub 2008 Sep 30.

Department of Biochemistry, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, New York 10461, USA.

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http://dx.doi.org/10.1021/bi801198mDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2657875PMC
October 2008