Publications by authors named "Emmanuel Karouzakis"

26Publications

TGF-β-induced epigenetic deregulation of SOCS3 facilitates STAT3 signaling to promote fibrosis.

J Clin Invest 2020 May;130(5):2347-2363

Department of Internal Medicine 3 - Rheumatology and Immunology, Friedrich-Alexander-Universität (FAU) Erlangen-Nürnberg and Universitätsklinikum Erlangen, Erlangen, Germany.

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http://dx.doi.org/10.1172/JCI122462DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7190914PMC
May 2020

Molecular Characterization of Human Lymph Node Stromal Cells During the Earliest Phases of Rheumatoid Arthritis.

Front Immunol 2019 20;10:1863. Epub 2019 Aug 20.

Department of Rheumatology, Center of Experimental Rheumatology, University Hospital of Zurich, Zurich, Switzerland.

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http://dx.doi.org/10.3389/fimmu.2019.01863DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6711342PMC
October 2020

TET1 is an important transcriptional activator of TNFα expression in macrophages.

PLoS One 2019 19;14(6):e0218551. Epub 2019 Jun 19.

Department of Rheumatology, Center of Experimental Rheumatology, University Hospital Zurich, University of Zurich, Zurich, Switzerland.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0218551PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6583962PMC
February 2020

Analysis of early changes in DNA methylation in synovial fibroblasts of RA patients before diagnosis.

Sci Rep 2018 05 9;8(1):7370. Epub 2018 May 9.

Center of Experimental Rheumatology, Department of Rheumatology, University of Zurich, Zurich, CH-8952, Switzerland.

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http://dx.doi.org/10.1038/s41598-018-24240-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5943364PMC
May 2018

The epigenetic architecture at gene promoters determines cell type-specific LPS tolerance.

J Autoimmun 2017 Sep 9;83:122-133. Epub 2017 Jul 9.

Center of Experimental Rheumatology, Department of Rheumatology, University Hospital Zurich, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.jaut.2017.07.001DOI Listing
September 2017

Epigenetic changes: the missing link.

Best Pract Res Clin Rheumatol 2014 Aug 22;28(4):577-87. Epub 2014 Nov 22.

Center of Experimental Rheumatology, University Hospital of Zurich, Zurich, Switzerland.

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http://dx.doi.org/10.1016/j.berh.2014.10.014DOI Listing
August 2014

Epigenome analysis reveals TBX5 as a novel transcription factor involved in the activation of rheumatoid arthritis synovial fibroblasts.

J Immunol 2014 Nov 15;193(10):4945-51. Epub 2014 Oct 15.

Center of Experimental Rheumatology, University Hospital Zurich, CH-8952 Schlieren, Switzerland.

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http://dx.doi.org/10.4049/jimmunol.1400066DOI Listing
November 2014

A novel Nrf2-miR-29-desmocollin-2 axis regulates desmosome function in keratinocytes.

Nat Commun 2014 Oct 6;5:5099. Epub 2014 Oct 6.

Department of Biology, Institute of Molecular Health Sciences, ETH Zurich, 8093 Zurich, Switzerland.

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http://dx.doi.org/10.1038/ncomms6099DOI Listing
October 2014

Inhibition of spermidine/spermine N1-acetyltransferase activity: a new therapeutic concept in rheumatoid arthritis.

Arthritis Rheumatol 2014 Jul;66(7):1723-33

Zurich Center of Integrative Human Physiology, Center of Experimental Rheumatology, and University Hospital Zurich, Zurich, Switzerland.

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http://dx.doi.org/10.1002/art.38574DOI Listing
July 2014

Genetics: a new interpretation of genetic studies in RA.

Nat Rev Rheumatol 2014 Apr 25;10(4):199-200. Epub 2014 Feb 25.

Center for Experimental Rheumatology, University Hospital Zurich, Gloriastrasse 23, Zurich CH 8091, Switzerland.

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http://dx.doi.org/10.1038/nrrheum.2014.21DOI Listing
April 2014

Increased recycling of polyamines is associated with global DNA hypomethylation in rheumatoid arthritis synovial fibroblasts.

Arthritis Rheum 2012 Jun 14;64(6):1809-17. Epub 2011 Dec 14.

University Hospital, Zurich, Switzerland.

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http://dx.doi.org/10.1002/art.34340DOI Listing
June 2012

7th meeting of the Global Arthritis Research Network.

Arthritis Res Ther 2011 Aug 23;13(4):303. Epub 2011 Aug 23.

Department of Rheumatology, University Hospital, Gloriastrasse 25, CH-8091 Zurich, Switzerland.

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http://dx.doi.org/10.1186/ar3340DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3239332PMC
August 2011

Epigenetic deregulation in rheumatoid arthritis.

Adv Exp Med Biol 2011 ;711:137-49

Center for Experimental Rheumatology, University Hospital Zurich, Gloriastrasse, Zurich, Switzerland.

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http://dx.doi.org/10.1007/978-1-4419-8216-2_10DOI Listing
June 2011

Altered expression of microRNA-203 in rheumatoid arthritis synovial fibroblasts and its role in fibroblast activation.

Arthritis Rheum 2011 Feb;63(2):373-81

Center of Experimental Rheumatology, University Hospital Zurich and Zurich Center of Integrative Human Physiology, Zurich, Switzerland.

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http://dx.doi.org/10.1002/art.30115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3116142PMC
February 2011

Trex-1 deficiency in rheumatoid arthritis synovial fibroblasts.

Arthritis Rheum 2010 Sep;62(9):2673-9

Center for Experimental Rheumatology, Zurich Center for Integrative Human Physiology, Zurich, Switzerland.

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http://dx.doi.org/10.1002/art.27567DOI Listing
September 2010

Epigenetics and rheumatoid arthritis: the role of SENP1 in the regulation of MMP-1 expression.

J Autoimmun 2010 Aug 15;35(1):15-22. Epub 2010 Jan 15.

Center of Experimental Rheumatology, University Hospital Zurich, Gloriastrasse 23-25, Zurich 8091, Switzerland.

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http://dx.doi.org/10.1016/j.jaut.2009.12.010DOI Listing
August 2010

DNA hypomethylation in rheumatoid arthritis synovial fibroblasts.

Arthritis Rheum 2009 Dec;60(12):3613-22

Zurich Center of Integrative Human Physiology, University Hospital, Zurich, Switzerland.

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http://dx.doi.org/10.1002/art.25018DOI Listing
December 2009

Epigenetic control in rheumatoid arthritis synovial fibroblasts.

Nat Rev Rheumatol 2009 May;5(5):266-72

Department of Rheumatology, University Hospital Zurich, Zurich, Switzerland.

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http://dx.doi.org/10.1038/nrrheum.2009.55DOI Listing
May 2009

Molecular and cellular basis of rheumatoid joint destruction.

Immunol Lett 2006 Jul 24;106(1):8-13. Epub 2006 May 24.

Center of Experimental Rheumatology, University Hospital Zurich, Switzerland.

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http://dx.doi.org/10.1016/j.imlet.2006.04.011DOI Listing
July 2006