Publications by authors named "Emmanouil Dermitzakis"

100Publications

Overview of PAX gene family: analysis of human tissue-specific variant expression and involvement in human disease.

Hum Genet 2020 Jul 29. Epub 2020 Jul 29.

Department of Environmental Health Sciences, Yale School of Public Health, 60 College Street, New Haven, CT, 06510, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00439-020-02212-9DOI Listing
July 2020

Bone status of young adults with periodic avoidance of dairy products since childhood.

Eur J Pediatr 2020 Apr 23;179(4):645-651. Epub 2019 Dec 23.

Department of Social Medicine, Preventive Medicine and Nutrition, Medical School, University of Crete, Heraklion, Greece.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00431-019-03542-1DOI Listing
April 2020

Accurate, scalable and integrative haplotype estimation.

Nat Commun 2019 11 28;10(1):5436. Epub 2019 Nov 28.

Department of Genetic Medicine and Development, University of Geneva Medical School, 1 rue Michel-Servet, 1211, Geneva, Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41467-019-13225-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6882857PMC
November 2019

Analysis of HCRTR2, GNB3, and ADH4 Gene Polymorphisms in a Southeastern European Caucasian Cluster Headache Population.

J Mol Neurosci 2020 Mar 25;70(3):467-474. Epub 2019 Nov 25.

Research Group of Clinical Pharmacology and Pharmacogenomics, Faculty of Pharmacy, School of Health Sciences, National and Kapodistrian University of Athens, Panepistimiopolis Zografou, 15771, Athens, Greece.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s12031-019-01439-0DOI Listing
March 2020

Cellular circadian period length inversely correlates with HbA levels in individuals with type 2 diabetes.

Diabetologia 2019 08 27;62(8):1453-1462. Epub 2019 May 27.

Department of Medicine, Division of Endocrinology, Diabetes, Hypertension and Nutrition, Faculty of Medicine, University of Geneva, Rue Michel-Servet, 1, CH-1211, 14, Geneva, Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00125-019-4907-0DOI Listing
August 2019

Expression estimation and eQTL mapping for HLA genes with a personalized pipeline.

PLoS Genet 2019 04 22;15(4):e1008091. Epub 2019 Apr 22.

Department of Genetics and Evolutionary Biology, Institute of Biosciences, University of São Paulo, São Paulo, Brazil.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1371/journal.pgen.1008091DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6497317PMC
April 2019

Dissecting Cell Lineage Specification and Sex Fate Determination in Gonadal Somatic Cells Using Single-Cell Transcriptomics.

Cell Rep 2019 03;26(12):3272-3283.e3

Department of Genetic Medicine and Development, University of Geneva, 1211 Geneva, Switzerland; iGE3, Institute of Genetics and Genomics of Geneva, University of Geneva, 1211 Geneva, Switzerland. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.celrep.2019.02.069DOI Listing
March 2019

High-fat diet impacts more changes in beta-cell compared to alpha-cell transcriptome.

PLoS One 2019 8;14(3):e0213299. Epub 2019 Mar 8.

Molecular Diabetes Laboratory, Division of Endocrinology, Diabetes, Hypertension and Nutrition, University Hospital/Diabetes Center/University of Geneva Medical School, Geneva, Switzerland.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0213299PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6407777PMC
December 2019

Sustained onabotulinumtoxinA therapeutic benefits in patients with chronic migraine over 3 years of treatment.

J Headache Pain 2018 Sep 17;19(1):87. Epub 2018 Sep 17.

Headache Outpatient Clinic, 1st Department of Neurology, National and Kapodistrian University of Athens, Athens, Greece.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s10194-018-0918-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6755578PMC
September 2018

Angiogenin and Osteoprotegerin are type II muscle specific myokines protecting pancreatic beta-cells against proinflammatory cytokines.

Sci Rep 2018 07 3;8(1):10072. Epub 2018 Jul 3.

UMR DIATHEC, EA 7294, Centre Européen d'Etude du Diabète, Université de Strasbourg, Fédération de Médecine Translationnelle de Strasbourg (FMTS), Bld René Leriche, 67200, Strasbourg, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41598-018-28117-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6030123PMC
July 2018

Deciphering Cell Lineage Specification during Male Sex Determination with Single-Cell RNA Sequencing.

Cell Rep 2018 02;22(6):1589-1599

Department of Genetic Medicine and Development, University of Geneva, 1211 Geneva, Switzerland; iGE3, Institute of Genetics and Genomics of Geneva, University of Geneva, 1211 Geneva, Switzerland. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.celrep.2018.01.043DOI Listing
February 2018

Age-dependent changes in mean and variance of gene expression across tissues in a twin cohort.

Hum Mol Genet 2018 02;27(4):732-741

Department of Twin Research and Genetic Epidemiology, King's College London, St Thomas' Campus, SE1 7EH London, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/hmg/ddx424DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5886097PMC
February 2018

The effect of genetic variation on promoter usage and enhancer activity.

Nat Commun 2017 11 7;8(1):1358. Epub 2017 Nov 7.

Department of Genetic Medicine and Development, University of Geneva, 1 Michel Servet, Geneva, CH1211, Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41467-017-01467-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5677018PMC
November 2017

Estimating the causal tissues for complex traits and diseases.

Nat Genet 2017 Dec 23;49(12):1676-1683. Epub 2017 Oct 23.

Department of Genetic Medicine and Development, University of Geneva Medical School, Geneva, Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ng.3981DOI Listing
December 2017

Predicting causal variants affecting expression by using whole-genome sequencing and RNA-seq from multiple human tissues.

Nat Genet 2017 Dec 23;49(12):1747-1751. Epub 2017 Oct 23.

Department of Genetic Medicine and Development, University of Geneva Medical School, Geneva, Switzerland.

View Article

Download full-text PDF

Source
http://www.nature.com/doifinder/10.1038/ng.3979
Publisher Site
http://dx.doi.org/10.1038/ng.3979DOI Listing
December 2017

A complete tool set for molecular QTL discovery and analysis.

Nat Commun 2017 05 18;8:15452. Epub 2017 May 18.

Department of Genetic Medicine and Development, University of Geneva, 1 Michel Servet, Geneva CH1211, Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ncomms15452DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5454369PMC
May 2017

Time-dependent genetic effects on gene expression implicate aging processes.

Genome Res 2017 04 16;27(4):545-552. Epub 2017 Mar 16.

Department of Genetic Medicine and Development, University of Geneva Medical School, 1211 Geneva 4, Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1101/gr.207688.116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5378173PMC
April 2017

Genetic Drivers of Epigenetic and Transcriptional Variation in Human Immune Cells.

Cell 2016 11;167(5):1398-1414.e24

Department of Human Genetics, The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1HH, UK; Department of Haematology, University of Cambridge, Cambridge Biomedical Campus, Long Road, Cambridge CB2 0PT, UK; British Heart Foundation Centre of Excellence, Division of Cardiovascular Medicine, Addenbrooke's Hospital, Hills Road, Cambridge CB2 0QQ, UK; The National Institute for Health Research Blood and Transplant Unit (NIHR BTRU) in Donor Health and Genomics at the University of Cambridge, Strangeways Research Laboratory, University of Cambridge, Wort's Causeway, Cambridge CB1 8RN, UK. Electronic address:

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S00928674163144
Publisher Site
http://dx.doi.org/10.1016/j.cell.2016.10.026DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5119954PMC
November 2016

Onabotulinumtoxin-A treatment in Greek patients with chronic migraine.

J Headache Pain 2016 Dec 17;17(1):84. Epub 2016 Sep 17.

Headache Outpatient Clinic, 1st Department of Neurology, National and Kapodistrian University of Athens, Athens, Greece.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5026980PMC
http://dx.doi.org/10.1186/s10194-016-0676-zDOI Listing
December 2016

Sequential transcriptional waves direct the differentiation of newborn neurons in the mouse neocortex.

Science 2016 Mar 3;351(6280):1443-6. Epub 2016 Mar 3.

Department of Basic Neurosciences, University of Geneva, Switzerland. Clinic of Neurology, Geneva University Hospital, Switzerland. Institute for Genetics and Genomics in Geneva (iGE3), University of Geneva, Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1126/science.aad8361DOI Listing
March 2016

IL-13 improves beta-cell survival and protects against IL-1beta-induced beta-cell death.

Mol Metab 2016 Feb 17;5(2):122-131. Epub 2015 Nov 17.

Department of Genetic Medicine and Development, University of Geneva Medical Center, Geneva, Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.molmet.2015.11.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4735661PMC
February 2016

Fast and efficient QTL mapper for thousands of molecular phenotypes.

Bioinformatics 2016 05 26;32(10):1479-85. Epub 2015 Dec 26.

Department of Genetic Medicine and Development, University of Geneva Medical School, Geneva, Switzerland Institute for Genetics and Genomics in Geneva (iGE3), University of Geneva, Geneva, 1211, Switzerland Swiss Institute of Bioinformatics, Geneva, 1211, Switzerland and.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/bioinformatics/btv722DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4866519PMC
May 2016

Alternative Splicing QTLs in European and African Populations.

Am J Hum Genet 2015 Oct;97(4):567-75

Department of Genetic Medicine and Development, University of Geneva Medical School, 1211 Geneva, Switzerland; Institute for Genetics and Genomics in Geneva (iGE3), University of Geneva, 1211 Geneva, Switzerland; Swiss Institute of Bioinformatics, 1211 Geneva, Switzerland; Center of Excellence for Genomic Medicine Research, King Abdulaziz University, Jeddah 21589, Saudi Arabia; Biomedical Research Foundation Academy of Athens, Athens 11527, Greece. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ajhg.2015.09.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4596912PMC
October 2015

Population Variation and Genetic Control of Modular Chromatin Architecture in Humans.

Cell 2015 Aug 20;162(5):1039-50. Epub 2015 Aug 20.

Swiss Institute of Bioinformatics, Lausanne 1015, Switzerland; Department of Genetic Medicine and Development, University of Geneva Medical School, Geneva 1211, Switzerland; Institute of Genetics and Genomics in Geneva, University of Geneva, Geneva 1211, Switzerland. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.cell.2015.08.001DOI Listing
August 2015

Integrated analysis of mRNA and miRNA expression in response to interleukin-6 in hepatocytes.

Data Brief 2015 Sep 10;4:226-8. Epub 2015 Jun 10.

Department of Genetic Medicine and Development, University of Geneva Medical School, 1211 Geneva, Switzerland ; Institute of Genetics and Genomics in Geneva (iGE3), 1211 Geneva, Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.dib.2015.05.023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4510544PMC
September 2015

Integrated analysis of mRNA and miRNA expression in response to interleukin-6 in hepatocytes.

Genomics 2015 Aug 12;106(2):107-15. Epub 2015 May 12.

Department of Genetic Medicine and Development, University of Geneva Medical School, 1211 Geneva, Switzerland; Institute of Genetics and Genomics in Geneva (iGE3), 1211 Geneva, Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ygeno.2015.05.001DOI Listing
August 2015

Sharing and Specificity of Co-expression Networks across 35 Human Tissues.

PLoS Comput Biol 2015 May 13;11(5):e1004220. Epub 2015 May 13.

Department of Computer Science, Stanford University, Stanford, California, United States of America.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1371/journal.pcbi.1004220DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4430528PMC
May 2015

Human genomics. The human transcriptome across tissues and individuals.

Science 2015 May;348(6235):660-5

Center for Genomic Regulation (CRG), Barcelona, Catalonia, Spain. Universitat Pompeu Fabra (UPF), Barcelona, Catalonia, Spain. Institut Hospital del Mar d'Investigacions Mèdiques (IMIM), Barcelona, Catalonia, Spain. Joint CRG-Barcelona Super Computing Center (BSC)-Institut de Recerca Biomedica (IRB) Program in Computational Biology, Barcelona, Catalonia, Spain.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1126/science.aaa0355DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4547472PMC
May 2015

Quantitative variability of 342 plasma proteins in a human twin population.

Mol Syst Biol 2015 Feb 4;11(1):786. Epub 2015 Feb 4.

Department of Biology, Institute of Molecular Systems Biology, ETH Zurich, Zurich, Switzerland Faculty of Science, University of Zurich, Zurich, Switzerland

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4358658PMC
http://dx.doi.org/10.15252/msb.20145728DOI Listing
February 2015

Tissue-specific effects of genetic and epigenetic variation on gene regulation and splicing.

PLoS Genet 2015 Jan 29;11(1):e1004958. Epub 2015 Jan 29.

Department of Genetic Medicine and Development, University of Geneva Medical School, Geneva, Switzerland; Institute of Genetics and Genomics in Geneva (iGE3), Geneva, Switzerland; Swiss Institute of Bioinformatics (SIB), Geneva, Switzerland; Center of Excellence in Genomic Medicine Research, KingAbdulaziz University, Jeddah, Saudi Arabia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1371/journal.pgen.1004958DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4310612PMC
January 2015

Short term exposure of beta cells to low concentrations of interleukin-1β improves insulin secretion through focal adhesion and actin remodeling and regulation of gene expression.

J Biol Chem 2015 Mar 13;290(10):6653-69. Epub 2015 Jan 13.

From the Department of Genetic Medicine and Development, University Medical Centre, University of Geneva, 1211 Geneva 4, Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1074/jbc.M114.611111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4358297PMC
March 2015

Biased allelic expression in human primary fibroblast single cells.

Am J Hum Genet 2015 Jan 31;96(1):70-80. Epub 2014 Dec 31.

Department of Genetic Medicine and Development, University of Geneva, 1211 Geneva, Switzerland; Institute of Genetics and Genomics of Geneva, 1211 Geneva, Switzerland; Service of Genetic Medicine, University Hospitals of Geneva, 1211 Geneva, Switzerland. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ajhg.2014.12.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4289680PMC
January 2015

Gene age predicts the strength of purifying selection acting on gene expression variation in humans.

Am J Hum Genet 2014 Dec;95(6):660-74

Department of Genetic Medicine and Development, University of Geneva Medical School, 1 Rue Michel-Servet, 1211 Geneva, Switzerland; Institute of Genetics and Genomics in Geneva, 1211 Geneva, Switzerland. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ajhg.2014.11.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4259975PMC
December 2014

Gene-gene and gene-environment interactions detected by transcriptome sequence analysis in twins.

Nat Genet 2015 Jan 1;47(1):88-91. Epub 2014 Dec 1.

1] Department of Genetic Medicine and Development, University of Geneva Medical School, Geneva, Switzerland. [2] Institute of Genetics and Genomics in Geneva, University of Geneva, Geneva, Switzerland. [3] Swiss Institute of Bioinformatics, Geneva, Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ng.3162DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4643454PMC
January 2015

Fractalkine (CX3CL1), a new factor protecting β-cells against TNFα.

Mol Metab 2014 Oct 11;3(7):731-41. Epub 2014 Aug 11.

Department of Genetic Medicine and Development, Geneva University, Geneva, Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.molmet.2014.07.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4209359PMC
October 2014

Putative cis-regulatory drivers in colorectal cancer.

Nature 2014 Aug 23;512(7512):87-90. Epub 2014 Jul 23.

1] Department of Genetic Medicine and Development, University of Geneva Medical School, 1211 Geneva, Switzerland [2] Institute for Genetics and Genomics in Geneva (iGE3), University of Geneva, 1211 Geneva, Switzerland [3] Swiss Institute of Bioinformatics, 1211 Geneva, Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nature13602DOI Listing
August 2014

Cis and trans effects of human genomic variants on gene expression.

PLoS Genet 2014 Jul 10;10(7):e1004461. Epub 2014 Jul 10.

Department of Genetic Medicine and Development, University of Geneva Medical School, Geneva, Switzerland; Institute of Genetics and Genomics in Geneva (iGE3), Geneva, Switzerland; Swiss Institute of Bioinformatics (SIB), Geneva, Switzerland; Center of Excellence for Genomic Medicine Research, King Abdulaziz University, Jeddah, Saudi Arabia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1371/journal.pgen.1004461DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4091791PMC
July 2014

Genetic and epigenetic regulation of human lincRNA gene expression.

Am J Hum Genet 2013 Dec 21;93(6):1015-26. Epub 2013 Nov 21.

Department of Genetic Medicine and Development, University of Geneva Medical School, 1 rue Michel-Servet, 1211 Geneva, Switzerland; Institute of Genetics and Genomics in Geneva (iGE3), 1211 Geneva, Switzerland; Institute for Information Transmission Problems (Kharkevich Institute), Russian Academy of Sciences, Moscow 127994, Russia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ajhg.2013.10.022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3852921PMC
December 2013

Identification and removal of low-complexity sites in allele-specific analysis of ChIP-seq data.

Bioinformatics 2014 Jan 18;30(2):165-71. Epub 2013 Nov 18.

Institute of Bioengineering, School of Life Sciences, École Polytechnique Fédérale de Lausanne, Swiss Institute of Bioinformatics, 1015, Lausanne, Switzerland, Department of Genetic Medicine and Development, University of Geneva Medical School, Institute of Genetics and Genomics in Geneva, University of Geneva, 1211, Geneva, Switzerland and Center for Integrative Genomics, Faculty of Biology and Medicine, University of Lausanne, 1011, Lausanne, Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/bioinformatics/btt667DOI Listing
January 2014

Reproducibility of high-throughput mRNA and small RNA sequencing across laboratories.

Nat Biotechnol 2013 Nov 15;31(11):1015-22. Epub 2013 Sep 15.

1] Department of Human Genetics, Leiden University Medical Center, Leiden, The Netherlands. [2] Netherlands Bioinformatics Centre, Leiden, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nbt.2702DOI Listing
November 2013

Immune response is a personal matter.

Elife 2013 Jul 16;2:e00899. Epub 2013 Jul 16.

is at the Department of Genetic Medicine and Development , University of Geneva Medical School , Geneva , Switzerland , the Institute of Genetics and Genomics in Geneva , Geneva , Switzerland , and the Swiss Institute of Bioinformatics , Geneva , Switzerland

View Article

Download full-text PDF

Source
http://dx.doi.org/10.7554/eLife.00899DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3713457PMC
July 2013

Passive and active DNA methylation and the interplay with genetic variation in gene regulation.

Elife 2013 Jun 4;2:e00523. Epub 2013 Jun 4.

Department of Genetic Medicine and Development, University of Geneva Medical School, Geneva, Switzerland; Institute of Genetics and Genomics in Geneva, Geneva, Switzerland [corrected]; Swiss Institute of Bioinformatics, Geneva, Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.7554/eLife.00523DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3673336PMC
June 2013

Sex-stratified genome-wide association studies including 270,000 individuals show sexual dimorphism in genetic loci for anthropometric traits.

Authors:
Joshua C Randall Thomas W Winkler Zoltán Kutalik Sonja I Berndt Anne U Jackson Keri L Monda Tuomas O Kilpeläinen Tõnu Esko Reedik Mägi Shengxu Li Tsegaselassie Workalemahu Mary F Feitosa Damien C Croteau-Chonka Felix R Day Tove Fall Teresa Ferreira Stefan Gustafsson Adam E Locke Iain Mathieson Andre Scherag Sailaja Vedantam Andrew R Wood Liming Liang Valgerdur Steinthorsdottir Gudmar Thorleifsson Emmanouil T Dermitzakis Antigone S Dimas Fredrik Karpe Josine L Min George Nicholson Deborah J Clegg Thomas Person Jon P Krohn Sabrina Bauer Christa Buechler Kristina Eisinger Amélie Bonnefond Philippe Froguel Jouke-Jan Hottenga Inga Prokopenko Lindsay L Waite Tamara B Harris Albert Vernon Smith Alan R Shuldiner Wendy L McArdle Mark J Caulfield Patricia B Munroe Henrik Grönberg Yii-Der Ida Chen Guo Li Jacques S Beckmann Toby Johnson Unnur Thorsteinsdottir Maris Teder-Laving Kay-Tee Khaw Nicholas J Wareham Jing Hua Zhao Najaf Amin Ben A Oostra Aldi T Kraja Michael A Province L Adrienne Cupples Nancy L Heard-Costa Jaakko Kaprio Samuli Ripatti Ida Surakka Francis S Collins Jouko Saramies Jaakko Tuomilehto Antti Jula Veikko Salomaa Jeanette Erdmann Christian Hengstenberg Christina Loley Heribert Schunkert Claudia Lamina H Erich Wichmann Eva Albrecht Christian Gieger Andrew A Hicks Asa Johansson Peter P Pramstaller Sekar Kathiresan Elizabeth K Speliotes Brenda Penninx Anna-Liisa Hartikainen Marjo-Riitta Jarvelin Ulf Gyllensten Dorret I Boomsma Harry Campbell James F Wilson Stephen J Chanock Martin Farrall Anuj Goel Carolina Medina-Gomez Fernando Rivadeneira Karol Estrada André G Uitterlinden Albert Hofman M Carola Zillikens Martin den Heijer Lambertus A Kiemeney Andrea Maschio Per Hall Jonathan Tyrer Alexander Teumer Henry Völzke Peter Kovacs Anke Tönjes Massimo Mangino Tim D Spector Caroline Hayward Igor Rudan Alistair S Hall Nilesh J Samani Antony Paul Attwood Jennifer G Sambrook Joseph Hung Lyle J Palmer Marja-Liisa Lokki Juha Sinisalo Gabrielle Boucher Heikki Huikuri Mattias Lorentzon Claes Ohlsson Niina Eklund Johan G Eriksson Cristina Barlassina Carlo Rivolta Ilja M Nolte Harold Snieder Melanie M Van der Klauw Jana V Van Vliet-Ostaptchouk Pablo V Gejman Jianxin Shi Kevin B Jacobs Zhaoming Wang Stephan J L Bakker Irene Mateo Leach Gerjan Navis Pim van der Harst Nicholas G Martin Sarah E Medland Grant W Montgomery Jian Yang Daniel I Chasman Paul M Ridker Lynda M Rose Terho Lehtimäki Olli Raitakari Devin Absher Carlos Iribarren Hanneke Basart Kees G Hovingh Elina Hyppönen Chris Power Denise Anderson John P Beilby Jennie Hui Jennifer Jolley Hendrik Sager Stefan R Bornstein Peter E H Schwarz Kati Kristiansson Markus Perola Jaana Lindström Amy J Swift Matti Uusitupa Mustafa Atalay Timo A Lakka Rainer Rauramaa Jennifer L Bolton Gerry Fowkes Ross M Fraser Jackie F Price Krista Fischer Kaarel Krjutå Kov Andres Metspalu Evelin Mihailov Claudia Langenberg Jian'an Luan Ken K Ong Peter S Chines Sirkka M Keinanen-Kiukaanniemi Timo E Saaristo Sarah Edkins Paul W Franks Göran Hallmans Dmitry Shungin Andrew David Morris Colin N A Palmer Raimund Erbel Susanne Moebus Markus M Nöthen Sonali Pechlivanis Kristian Hveem Narisu Narisu Anders Hamsten Steve E Humphries Rona J Strawbridge Elena Tremoli Harald Grallert Barbara Thorand Thomas Illig Wolfgang Koenig Martina Müller-Nurasyid Annette Peters Bernhard O Boehm Marcus E Kleber Winfried März Bernhard R Winkelmann Johanna Kuusisto Markku Laakso Dominique Arveiler Giancarlo Cesana Kari Kuulasmaa Jarmo Virtamo John W G Yarnell Diana Kuh Andrew Wong Lars Lind Ulf de Faire Bruna Gigante Patrik K E Magnusson Nancy L Pedersen George Dedoussis Maria Dimitriou Genovefa Kolovou Stavroula Kanoni Kathleen Stirrups Lori L Bonnycastle Inger Njølstad Tom Wilsgaard Andrea Ganna Emil Rehnberg Aroon Hingorani Mika Kivimaki Meena Kumari Themistocles L Assimes Inês Barroso Michael Boehnke Ingrid B Borecki Panos Deloukas Caroline S Fox Timothy Frayling Leif C Groop Talin Haritunians David Hunter Erik Ingelsson Robert Kaplan Karen L Mohlke Jeffrey R O'Connell David Schlessinger David P Strachan Kari Stefansson Cornelia M van Duijn Gonçalo R Abecasis Mark I McCarthy Joel N Hirschhorn Lu Qi Ruth J F Loos Cecilia M Lindgren Kari E North Iris M Heid

PLoS Genet 2013 Jun 6;9(6):e1003500. Epub 2013 Jun 6.

Wellcome Trust Sanger Institute, Hinxton, Cambridge, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1371/journal.pgen.1003500DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3674993PMC
June 2013

Cell-type, allelic, and genetic signatures in the human pancreatic beta cell transcriptome.

Genome Res 2013 Sep 28;23(9):1554-62. Epub 2013 May 28.

Department of Genetic Medicine and Development, University of Geneva Medical School, Geneva 1211, Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1101/gr.150706.112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3759730PMC
September 2013

Congruence of additive and non-additive effects on gene expression estimated from pedigree and SNP data.

PLoS Genet 2013 May 16;9(5):e1003502. Epub 2013 May 16.

University of Queensland Diamantina Institute, University of Queensland, Princess Alexandra Hospital, Brisbane, Queensland, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1371/journal.pgen.1003502DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3656157PMC
May 2013

Expression quantitative trait loci: present and future.

Philos Trans R Soc Lond B Biol Sci 2013 6;368(1620):20120362. Epub 2013 May 6.

Department of Genetic Medicine and Development, University of Geneva Medical School, Geneva 1211, Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1098/rstb.2012.0362DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3682727PMC
December 2013

Genomic variation and its impact on gene expression in Drosophila melanogaster.

PLoS Genet 2012 15;8(11):e1003055. Epub 2012 Nov 15.

Laboratory of Systems Biology and Genetics, Institute of Bioengineering, School of Life Sciences, École Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1371/journal.pgen.1003055DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3499359PMC
May 2013