Emma Lees

Emma Lees

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Emma Lees

Emma Lees

Publications by authors named "Emma Lees"

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39Publications

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Cyclophosphamide Enhances Cancer Antibody Immunotherapy in the Resistant Bone Marrow Niche by Modulating Macrophage FcγR Expression.

Cancer Immunol Res 2019 Nov 26;7(11):1876-1890. Epub 2019 Aug 26.

Koch Institute for Integrative Cancer Research and Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts.

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http://dx.doi.org/10.1158/2326-6066.CIR-18-0835DOI Listing
November 2019

Response to comment by Moxon et al.

Clin Sci (Lond) 2018 01 2;132(1):39-41. Epub 2018 Jan 2.

Institute of medical sciences, Aberdeen Cardiovascular and Diabetes Centre, School of Medicine, Medical Sciences and Nutrition, University of Aberdeen, Aberdeen, U.K.

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http://dx.doi.org/10.1042/CS20171555DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5869856PMC
January 2018

Direct comparison of methionine restriction with leucine restriction on the metabolic health of C57BL/6J mice.

Sci Rep 2017 08 30;7(1):9977. Epub 2017 Aug 30.

Institute of Medical Sciences, School of Medicine, Medical Sciences and Nutrition, University of Aberdeen, Aberdeen, UK.

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http://dx.doi.org/10.1038/s41598-017-10381-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5577041PMC
August 2017

Project DRIVE: A Compendium of Cancer Dependencies and Synthetic Lethal Relationships Uncovered by Large-Scale, Deep RNAi Screening.

Cell 2017 Jul;170(3):577-592.e10

Novartis Institutes for Biomedical Research, Oncology Disease Area, Basel 4002, Switzerland; Cambridge, MA 02139, USA; and Emeryville, CA 94608, USA.

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http://dx.doi.org/10.1016/j.cell.2017.07.005DOI Listing
July 2017

Methionine restriction improves renal insulin signalling in aged kidneys.

Mech Ageing Dev 2016 07 21;157:35-43. Epub 2016 Jul 21.

Institute of Medical Sciences, University of Aberdeen, College of Life Sciences and Medicine, Foresterhill Health Campus, Aberdeen, UK. Electronic address:

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http://dx.doi.org/10.1016/j.mad.2016.07.003DOI Listing
July 2016

The Public Repository of Xenografts Enables Discovery and Randomized Phase II-like Trials in Mice.

Authors:
Elizabeth C Townsend Mark A Murakami Alexandra Christodoulou Amanda L Christie Johannes Köster Tiffany A DeSouza Elizabeth A Morgan Scott P Kallgren Huiyun Liu Shuo-Chieh Wu Olivia Plana Joan Montero Kristen E Stevenson Prakash Rao Raga Vadhi Michael Andreeff Philippe Armand Karen K Ballen Patrizia Barzaghi-Rinaudo Sarah Cahill Rachael A Clark Vesselina G Cooke Matthew S Davids Daniel J DeAngelo David M Dorfman Hilary Eaton Benjamin L Ebert Julia Etchin Brant Firestone David C Fisher Arnold S Freedman Ilene A Galinsky Hui Gao Jacqueline S Garcia Francine Garnache-Ottou Timothy A Graubert Alejandro Gutierrez Ensar Halilovic Marian H Harris Zachary T Herbert Steven M Horwitz Giorgio Inghirami Andrew M Intlekofer Moriko Ito Shai Izraeli Eric D Jacobsen Caron A Jacobson Sébastien Jeay Irmela Jeremias Michelle A Kelliher Raphael Koch Marina Konopleva Nadja Kopp Steven M Kornblau Andrew L Kung Thomas S Kupper Nicole R LeBoeuf Ann S LaCasce Emma Lees Loretta S Li A Thomas Look Masato Murakami Markus Muschen Donna Neuberg Samuel Y Ng Oreofe O Odejide Stuart H Orkin Rachel R Paquette Andrew E Place Justine E Roderick Jeremy A Ryan Stephen E Sallan Brent Shoji Lewis B Silverman Robert J Soiffer David P Steensma Kimberly Stegmaier Richard M Stone Jerome Tamburini Aaron R Thorner Paul van Hummelen Martha Wadleigh Marion Wiesmann Andrew P Weng Jens U Wuerthner David A Williams Bruce M Wollison Andrew A Lane Anthony Letai Monica M Bertagnolli Jerome Ritz Myles Brown Henry Long Jon C Aster Margaret A Shipp James D Griffin David M Weinstock

Cancer Cell 2016 07 11;30(1):183. Epub 2016 Jul 11.

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http://dx.doi.org/10.1016/j.ccell.2016.06.008DOI Listing
July 2016

The Public Repository of Xenografts Enables Discovery and Randomized Phase II-like Trials in Mice.

Authors:
Elizabeth C Townsend Mark A Murakami Alexandra Christodoulou Amanda L Christie Johannes Köster Tiffany A DeSouza Elizabeth A Morgan Scott P Kallgren Huiyun Liu Shuo-Chieh Wu Olivia Plana Joan Montero Kristen E Stevenson Prakash Rao Raga Vadhi Michael Andreeff Philippe Armand Karen K Ballen Patrizia Barzaghi-Rinaudo Sarah Cahill Rachael A Clark Vesselina G Cooke Matthew S Davids Daniel J DeAngelo David M Dorfman Hilary Eaton Benjamin L Ebert Julia Etchin Brant Firestone David C Fisher Arnold S Freedman Ilene A Galinsky Hui Gao Jacqueline S Garcia Francine Garnache-Ottou Timothy A Graubert Alejandro Gutierrez Ensar Halilovic Marian H Harris Zachary T Herbert Steven M Horwitz Giorgio Inghirami Andrew M Intlekofer Moriko Ito Shai Izraeli Eric D Jacobsen Caron A Jacobson Sébastien Jeay Irmela Jeremias Michelle A Kelliher Raphael Koch Marina Konopleva Nadja Kopp Steven M Kornblau Andrew L Kung Thomas S Kupper Nicole R LeBoeuf Ann S LaCasce Emma Lees Loretta S Li A Thomas Look Masato Murakami Markus Muschen Donna Neuberg Samuel Y Ng Oreofe O Odejide Stuart H Orkin Rachel R Paquette Andrew E Place Justine E Roderick Jeremy A Ryan Stephen E Sallan Brent Shoji Lewis B Silverman Robert J Soiffer David P Steensma Kimberly Stegmaier Richard M Stone Jerome Tamburini Aaron R Thorner Paul van Hummelen Martha Wadleigh Marion Wiesmann Andrew P Weng Jens U Wuerthner David A Williams Bruce M Wollison Andrew A Lane Anthony Letai Monica M Bertagnolli Jerome Ritz Myles Brown Henry Long Jon C Aster Margaret A Shipp James D Griffin David M Weinstock

Cancer Cell 2016 04;29(4):574-586

Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, 450 Brookline Avenue, Dana 510B, MA 02215, USA; Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2016.03.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5177991PMC
April 2016

Effects of hepatic protein tyrosine phosphatase 1B and methionine restriction on hepatic and whole-body glucose and lipid metabolism in mice.

Metabolism 2015 Feb 5;64(2):305-14. Epub 2014 Nov 5.

Institute of Medical Sciences, School of Medical Sciences, University of Aberdeen, Aberdeen, UK. Electronic address:

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http://dx.doi.org/10.1016/j.metabol.2014.10.038DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4390031PMC
February 2015

Methionine restriction restores a younger metabolic phenotype in adult mice with alterations in fibroblast growth factor 21.

Aging Cell 2014 Oct 17;13(5):817-27. Epub 2014 Jun 17.

Institute of Medical Sciences, College of Life Sciences and Medicine, University of Aberdeen, Aberdeen, AB25 2ZD, UK.

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http://dx.doi.org/10.1111/acel.12238DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4331744PMC
October 2014

Polymer-coated nanoparticles: a universal tool for biolabelling experiments.

Small 2011 Nov 19;7(22):3113-27. Epub 2011 Sep 19.

Fachbereich Physik and Wissenschaftliches Zentrum für, Materialwissenschaften, Philipps Universität Marburg, Marburg, Germany.

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http://doi.wiley.com/10.1002/smll.201100608
Publisher Site
http://dx.doi.org/10.1002/smll.201100608DOI Listing
November 2011

The preparation of colloidally stable, water-soluble, biocompatible, semiconductor nanocrystals with a small hydrodynamic diameter.

ACS Nano 2009 May;3(5):1121-8

School of Chemistry and Bio21 Institute, University of Melbourne, Parkville, VIC 3010, Australia.

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http://dx.doi.org/10.1021/nn900144nDOI Listing
May 2009

Experimental determination of quantum dot size distributions, ligand packing densities, and bioconjugation using analytical ultracentrifugation.

Nano Lett 2008 Sep 30;8(9):2883-90. Epub 2008 Jul 30.

School of Chemistry and Bio21 Institute, University of Melbourne, Parkville, Victoria 3010, Australia.

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http://pubs.acs.org/doi/abs/10.1021/nl801629f
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http://dx.doi.org/10.1021/nl801629fDOI Listing
September 2008

In vivo identification of novel STAT5 target genes.

Nucleic Acids Res 2008 Jun 20;36(11):3802-18. Epub 2008 May 20.

Schering-Plough Biopharma, 901 California Avenue, Palo Alto, CA 94304, USA.

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http://dx.doi.org/10.1093/nar/gkn271DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2441806PMC
June 2008

Human CDK2 inhibition modifies the dynamics of chromatin-bound minichromosome maintenance complex and replication protein A.

Cell Cycle 2005 Sep 26;4(9):1254-63. Epub 2005 Sep 26.

Department of Discovery Research, DNAX Research, Incorporated, Palo Alto, California 94304, USA.

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https://www.tandfonline.com/doi/full/10.4161/cc.4.9.1975
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http://dx.doi.org/10.4161/cc.4.9.1975DOI Listing
September 2005

Intra-S-phase checkpoint activation by direct CDK2 inhibition.

Mol Cell Biol 2004 Jul;24(14):6268-77

Molecular Oncology Laboratory, Department of Discovery Research, DNAX Research, Inc., Palo Alto, CA 94304, USA.

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http://dx.doi.org/10.1128/MCB.24.14.6268-6277.2004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC434231PMC
July 2004

Role for BRG1 in cell cycle control and tumor suppression.

Mol Cell Biol 2004 Jan;24(1):362-76

DNAX Research Inc., Palo Alto, California 94304-1104, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC303366PMC
http://dx.doi.org/10.1128/mcb.24.1.362-376.2004DOI Listing
January 2004

Chromatin acetylation and remodeling at the Cis promoter during STAT5-induced transcription.

Nucleic Acids Res 2003 Dec;31(23):6882-90

Department of Discovery Research, DNAX Research Inc., 901 California Avenue, Palo Alto, CA 94304, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC290274PMC
http://dx.doi.org/10.1093/nar/gkg907DOI Listing
December 2003

AuroraA overexpression overrides the mitotic spindle checkpoint triggered by nocodazole, a microtubule destabilizer.

Oncogene 2003 Nov;22(51):8293-301

DNAX Research Inc., Palo Alto, CA 94304, USA.

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http://dx.doi.org/10.1038/sj.onc.1206873DOI Listing
November 2003

The product of the candidate prostate cancer susceptibility gene ELAC2 interacts with the gamma-tubulin complex.

Int J Cancer 2003 Apr;104(3):283-8

DNAX Research Institute, Department of Oncology, Palo Alto, CA 94304, USA.

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http://doi.wiley.com/10.1002/ijc.10945
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http://dx.doi.org/10.1002/ijc.10945DOI Listing
April 2003