Emma Larkin

Emma Larkin

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Emma Larkin

Emma Larkin

Publications by authors named "Emma Larkin"

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Trends in health care utilization for asthma exacerbations among diverse populations with asthma in the United States.

J Allergy Clin Immunol Pract 2018 Jan - Feb;6(1):295-297.e5. Epub 2017 Sep 19.

Department of Medicine, Vanderbilt University Medical Center, Nashville, Tenn; Department of Biostatistics, Vanderbilt University Medical Center, Nashville, Tenn. Electronic address:

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http://dx.doi.org/10.1016/j.jaip.2017.07.038DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6190591PMC
October 2019

Nasopharyngeal Lactobacillus is associated with a reduced risk of childhood wheezing illnesses following acute respiratory syncytial virus infection in infancy.

J Allergy Clin Immunol 2018 11 10;142(5):1447-1456.e9. Epub 2018 Jan 10.

Center for Asthma Research, Vanderbilt University School of Medicine, Nashville, Tenn; Department of Medicine, Vanderbilt University School of Medicine, Nashville, Tenn. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2017.10.049DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6039278PMC
November 2018

Association of newborn screening metabolites with risk of wheezing in childhood.

Pediatr Res 2018 11 1;84(5):619-624. Epub 2018 Jun 1.

Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.

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http://dx.doi.org/10.1038/s41390-018-0070-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274622PMC
November 2018

Using urine metabolomics to understand the pathogenesis of infant respiratory syncytial virus (RSV) infection and its role in childhood wheezing.

Metabolomics 2018 10 1;14(10):135. Epub 2018 Oct 1.

Division of Allergy, Pulmonary and Critical Care Medicine, Department of Medicine, Vanderbilt University School of Medicine, 2525 West End Avenue, Suite 450, Nashville, TN, 37203, USA.

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http://link.springer.com/10.1007/s11306-018-1431-z
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http://dx.doi.org/10.1007/s11306-018-1431-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6557166PMC
October 2018

Racial disparities in family-provider interactions for pediatric asthma care.

J Asthma 2018 04 14;55(4):424-429. Epub 2017 Jul 14.

g Center for Healthcare Research in Pediatrics, Department of Population Medicine , Harvard Pilgrim Health Care Institute and Harvard Medical School , Boston , MA , USA.

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http://dx.doi.org/10.1080/02770903.2017.1337790DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6340291PMC
April 2018

Clinical and Biological Insights Into Combined Post- and Pre-Capillary Pulmonary Hypertension.

J Am Coll Cardiol 2016 Dec;68(23):2525-2536

Vanderbilt Center for Translational and Clinical Cardiovascular Research, Vanderbilt University School of Medicine, Nashville, Tennessee; Division of Cardiovascular Medicine, Department of Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee.

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http://dx.doi.org/10.1016/j.jacc.2016.09.942DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5157701PMC
December 2016

Comparison of Heritability Estimation and Linkage Analysis for Multiple Traits Using Principal Component Analyses.

Genet Epidemiol 2016 Apr;40(3):222-32

Department of Epidemiology and Biostatistics, School of Medicine, Case Western Reserve University, Cleveland, Ohio, United States of America.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5083066PMC
http://dx.doi.org/10.1002/gepi.21957DOI Listing
April 2016

A simple respiratory severity score that may be used in evaluation of acute respiratory infection.

BMC Res Notes 2016 Feb 12;9:85. Epub 2016 Feb 12.

Vanderbilt Center for Asthma Research, Vanderbilt University, 1215 21st Avenue South 6000, Medical Center East, North Tower, Nashville, TN, 37232-8300, USA.

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http://dx.doi.org/10.1186/s13104-016-1899-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4751705PMC
February 2016

Common variants in DRD2 are associated with sleep duration: the CARe consortium.

Hum Mol Genet 2016 Jan 13;25(1):167-79. Epub 2015 Oct 13.

Division of Sleep and Circadian Disorders and Division of Sleep Medicine, Harvard Medical School, Boston, MA 02115, USA, Center for Human Genetic Research and Department of Anesthesia, Pain, and Critical Care Medicine, Massachusetts General Hospital, Boston, MA 02114, USA and Program in Medical and Population Genetics, Broad Institute, Cambridge, MA 02142, USA.

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http://dx.doi.org/10.1093/hmg/ddv434DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4690488PMC
January 2016

β2-Adrenergic receptor promoter haplotype influences the severity of acute viral respiratory tract infection during infancy: a prospective cohort study.

BMC Med Genet 2015 Sep 14;16:82. Epub 2015 Sep 14.

Division of Pediatric Allergy, Immunology and Pulmonary, Department of Pediatrics, Vanderbilt University School of Medicine, 2200 Children's Way, 11215 Doctor's Office Tower, Nashville, TN, 37232, USA.

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http://dx.doi.org/10.1186/s12881-015-0229-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4570703PMC
September 2015

Urine Club Cell 16-kDa Secretory Protein and Childhood Wheezing Illnesses After Lower Respiratory Tract Infections in Infancy.

Pediatr Allergy Immunol Pulmonol 2015 Sep;28(3):158-164

Division of Allergy, Pulmonary, and Critical Care Medicine, Department of Medicine, Vanderbilt University School of Medicine , Nashville, Tennessee. ; Vanderbilt Center for Asthma and Environmental Health Sciences Research, Vanderbilt University , Nashville, Tennessee.

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http://dx.doi.org/10.1089/ped.2015.0528DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4580139PMC
September 2015

Genes associated with RSV lower respiratory tract infection and asthma: the application of genetic epidemiological methods to understand causality.

Future Virol 2015 Jul;10(7):883-897

Department of Medicine, Division of Allergy, Pulmonary & Critical Care Medicine, Vanderbilt University Medical Center, Nashville, TN 37232, USA.

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https://www.futuremedicine.com/doi/10.2217/fvl.15.55
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http://dx.doi.org/10.2217/fvl.15.55DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4603287PMC
July 2015

Respiratory Severity Score Separates Upper Versus Lower Respiratory Tract Infections and Predicts Measures of Disease Severity.

Pediatr Allergy Immunol Pulmonol 2015 Jun;28(2):117-120

Division of Allergy, Pulmonary, and Critical Care Medicine, Department of Medicine, and Center for Asthma and Environmental Sciences Research, Vanderbilt University School of Medicine , Nashville, Tennessee.

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http://dx.doi.org/10.1089/ped.2014.0463DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4491158PMC
June 2015

Use of leukotriene receptor antagonists are associated with a similar risk of asthma exacerbations as inhaled corticosteroids.

J Allergy Clin Immunol Pract 2014 Sep-Oct;2(5):607-13. Epub 2014 Jul 25.

Center for Child Health Care Studies, Department of Population Medicine, Harvard Pilgrim Health Care Institute and Harvard Medical School, Boston, Mass; Division of General Pediatrics, Department of Pediatrics, Children's Hospital, Boston, Mass; Harvard Medical School, Boston, Mass; Division of Research, Kaiser Permanente Northern California, Oakland, Calif.

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http://dx.doi.org/10.1016/j.jaip.2014.05.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6557573PMC
May 2015

Prevalence and characteristics of medication sharing behavior in a pediatric Medicaid population with asthma.

Ann Allergy Asthma Immunol 2015 Feb 6;114(2):151-3. Epub 2014 Dec 6.

Division of Allergy, Pulmonary, and Critical Care Medicine, Department of Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee.

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http://dx.doi.org/10.1016/j.anai.2014.11.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4308417PMC
February 2015

Primary adherence to controller medications for asthma is poor.

Ann Am Thorac Soc 2015 Feb;12(2):161-6

1 Center for Child Health Care Studies, Department of Population Medicine, Harvard Pilgrim Health Care Institute and Harvard Medical School.

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http://dx.doi.org/10.1513/AnnalsATS.201410-459OCDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4342835PMC
February 2015

Statin exposure is associated with decreased asthma-related emergency department visits and oral corticosteroid use.

Am J Respir Crit Care Med 2013 Nov;188(9):1076-82

1 Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.1164/rccm.201306-1017OCDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3863744PMC
November 2013

Longitudinal analysis casts doubt on the presence of genetic anticipation in heritable pulmonary arterial hypertension.

Am J Respir Crit Care Med 2012 Nov 23;186(9):892-6. Epub 2012 Aug 23.

Vanderbilt University Institute for Medicine and Public Health, Vanderbilt Medical Center North, Nashville, TN 37232-2650, USA.

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http://dx.doi.org/10.1164/rccm.201205-0886OCDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3530218PMC
November 2012

Relationship of maternal vitamin D level with maternal and infant respiratory disease.

Am J Obstet Gynecol 2011 Sep 13;205(3):215.e1-7. Epub 2011 Apr 13.

Department of Pediatrics, Vanderbilt University School of Medicine, Nashville, TN, USA.

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http://dx.doi.org/10.1016/j.ajog.2011.04.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3171620PMC
September 2011

The landscape of recombination in African Americans.

Nature 2011 Jul 20;476(7359):170-5. Epub 2011 Jul 20.

Wellcome Trust Centre for Human Genetics, Oxford University, Roosevelt Drive, Oxford OX3 7BN, UK.

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http://dx.doi.org/10.1038/nature10336DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3154982PMC
July 2011

Short duration of sleep increases risk of colorectal adenoma.

Cancer 2011 Feb 8;117(4):841-7. Epub 2010 Oct 8.

Department of Family Medicine, Case Western Reserve University, Cleveland, Ohio, USA.

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http://dx.doi.org/10.1002/cncr.25507DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3021092PMC
February 2011

Agreement of blood spot card measurements of vitamin D levels with serum, whole blood specimen types and a dietary recall instrument.

PLoS One 2011 Jan 31;6(1):e16602. Epub 2011 Jan 31.

Division of Allergy, Pulmonary and Critical Care, Department of Medicine, Vanderbilt University, Nashville, Tennessee, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0016602PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3031596PMC
January 2011

Study of the relationship between the interleukin-6 gene and obstructive sleep apnea.

Clin Transl Sci 2010 Dec;3(6):337-9

Division of Allergy, Pulmonary and Critical Care, Vanderbilt University Medical Center, Nashville, Tenessee, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3078635PMC
http://dx.doi.org/10.1111/j.1752-8062.2010.00236.xDOI Listing
December 2010

A candidate gene study of obstructive sleep apnea in European Americans and African Americans.

Am J Respir Crit Care Med 2010 Oct 10;182(7):947-53. Epub 2010 Jun 10.

Division of Allergy, Pulmonary and Critical Care, Vanderbilt University Medical Center, Nashville, Tennessee, USA.

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http://dx.doi.org/10.1164/rccm.201002-0192OCDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2970865PMC
October 2010

Heritability of abnormalities in cardiopulmonary coupling in sleep apnea: use of an electrocardiogram-based technique.

Sleep 2010 May;33(5):643-6

Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine, University Hospitals Case Medical Center, Cleveland, Ohio 44106-6003, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2864879PMC
http://dx.doi.org/10.1093/sleep/33.5.643DOI Listing
May 2010

Population stratification and patterns of linkage disequilibrium.

Genet Epidemiol 2009 ;33 Suppl 1:S88-92

Department of Psychiatry, Washington University School of Medicine, St. Louis, Missouri 63110, USA.

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http://dx.doi.org/10.1002/gepi.20478DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3133943PMC
March 2010

Modeling the complex gene x environment interplay in the simulated rheumatoid arthritis GAW15 data using latent variable structural equation modeling.

BMC Proc 2007 18;1 Suppl 1:S118. Epub 2007 Dec 18.

Division of Genetic and Molecular Epidemiology, Case Western Reserve University, Cleveland, OH 44106-7281, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2367478PMC
http://dx.doi.org/10.1186/1753-6561-1-s1-s118DOI Listing
December 2009

Comparison of affected sibling-pair linkage methods to identify gene x gene interaction in GAW15 simulated data.

BMC Proc 2007 18;1 Suppl 1:S66. Epub 2007 Dec 18.

Department of Epidemiology and Biostatistics, Case Western Reserve University, Triangle Building, Suite 260, 11400 Euclid Avenue, Cleveland, Ohio 44106, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2367530PMC
http://dx.doi.org/10.1186/1753-6561-1-s1-s66DOI Listing
December 2009

Assessing the impact of global versus local ancestry in association studies.

BMC Proc 2009 Dec 15;3 Suppl 7:S107. Epub 2009 Dec 15.

Department of Epidemiology and Biostatistics, Division of Genetic and Molecular Epidemiology, Case Western Reserve University School of Medicine, Wolstein Research Building, 2103 Cornell Road, Cleveland, Ohio 44106 USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2795878PMC
http://dx.doi.org/10.1186/1753-6561-3-s7-s107DOI Listing
December 2009

Multivariate association analysis of the components of metabolic syndrome from the Framingham Heart Study.

BMC Proc 2009 Dec 15;3 Suppl 7:S42. Epub 2009 Dec 15.

Department of Epidemiology and Biostatistics, Division of Genetic and Molecular Epidemiology, Case Western Reserve University, 11400 Euclid Avenue, Suite 260, Cleveland, Ohio 44106, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2795941PMC
http://dx.doi.org/10.1186/1753-6561-3-s7-s42DOI Listing
December 2009

Empirical evidence for "syndrome Z": a hierarchical 5-factor model of the metabolic syndrome incorporating sleep disturbance measures.

Sleep 2009 May;32(5):615-22

Department of Epidemiology and Biostatistics, Case Western Reserve University, 2103 Cornell Road, Cleveland, OH 44106-7281, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2675896PMC
http://dx.doi.org/10.1093/sleep/32.5.615DOI Listing
May 2009

The association of angiotensin converting enzyme (ACE) polymorphisms with sleep apnea and hypertension.

Sleep 2007 Apr;30(4):531-3

Division of Pulmonary, Critical Care and Sleep Medicine, University Hospital and Case Western Reserve University, Cleveland, OH, USA.

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http://dx.doi.org/10.1093/sleep/30.4.531DOI Listing
April 2007

Apolipoprotein E and obstructive sleep apnea: evaluating whether a candidate gene explains a linkage peak.

Genet Epidemiol 2006 Feb;30(2):101-10

Department of Epidemiology and Biostatistics, Case Western Reserve University, 11400 Euclid Avenue, Ste. 260, Cleveland, OH 44106-6083, USA.

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http://dx.doi.org/10.1002/gepi.20127DOI Listing
February 2006

Self-reported race and genetic admixture.

N Engl J Med 2006 Jan;354(4):421-2

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http://dx.doi.org/10.1056/NEJMc052515DOI Listing
January 2006

A regression based transmission/disequilibrium test for binary traits: the power of joint tests for linkage and association.

BMC Genet 2005 Dec 30;6 Suppl 1:S95. Epub 2005 Dec 30.

Case Western Reserve University, Department of Epidemiology and Biostatistics, Cleveland, OH 44106, USA.

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http://dx.doi.org/10.1186/1471-2156-6-S1-S95DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1866684PMC
December 2005

Variation of C-reactive protein levels in adolescents: association with sleep-disordered breathing and sleep duration.

Circulation 2005 Apr;111(15):1978-84

Department of Epidemiology and Biostatistics, School of Medicine, Case Western Reserve University, Triangle Building Suite 260, 10400 Euclid Ave, Cleveland, OH 44106, USA.

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http://dx.doi.org/10.1161/01.CIR.0000161819.76138.5EDOI Listing
April 2005

Sex influences endothelial function in sleep-disordered breathing.

Sleep 2004 Sep;27(6):1113-20

Division of Cardiology, Case Western Reserve University, University Hospitals of Cleveland, OH, USA.

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http://dx.doi.org/10.1093/sleep/27.6.1113DOI Listing
September 2004

Whole genome scan for obstructive sleep apnea and obesity in African-American families.

Am J Respir Crit Care Med 2004 Jun 7;169(12):1314-21. Epub 2004 Apr 7.

Western Australian Institute for Medical Research, Centre for Medical Research, University of Western Australia, Perth, Australia.

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http://dx.doi.org/10.1164/rccm.200304-493OCDOI Listing
June 2004

Variation in childhood asthma among former preterm infants.

J Pediatr 2004 Mar;144(3):321-6

Department of Pediatrics, Rainbow Babies and Children's Hospital, University Hospitals of Cleveland, Case Western Reserve University, Cleveland, Ohio, USA.

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http://dx.doi.org/10.1016/j.jpeds.2003.11.029DOI Listing
March 2004

Relationship between obstructive sleep apnea and diurnal leptin rhythms.

Sleep 2004 Mar;27(2):235-9

Rainbow Babies and Children's Hospital, Cleveland, OH, USA.

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http://dx.doi.org/10.1093/sleep/27.2.235DOI Listing
March 2004

Decreased quality of life associated with obesity in school-aged children.

Arch Pediatr Adolesc Med 2003 Dec;157(12):1206-11

Department of Pediatrics, Rainbow Babies & Children's Hospital, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA.

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http://dx.doi.org/10.1001/archpedi.157.12.1206DOI Listing
December 2003

Predictors of longitudinal change in sleep-disordered breathing in a nonclinic population.

Sleep 2003 Sep;26(6):703-9

Department of Pediatrics, Division of Clinical Epidemiology, Case Western Reserve University, Rainbow Babies and Children's Hospital, Cleveland, Ohio 44106-6003, USA.

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http://dx.doi.org/10.1093/sleep/26.6.703DOI Listing
September 2003

Sleep-disordered breathing and cognitive impairment in elderly Japanese-American men.

Sleep 2003 Aug;26(5):596-9

Laboratory of Epidemiology, Demography, and Biometry, National Institute on Aging, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1093/sleep/26.5.596DOI Listing
August 2003

Incidence of sleep-disordered breathing in an urban adult population: the relative importance of risk factors in the development of sleep-disordered breathing.

JAMA 2003 May;289(17):2230-7

Veterans Affairs Boston Healthcare System and Channing Laboratory, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Mass 02115, USA.

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http://dx.doi.org/10.1001/jama.289.17.2230DOI Listing
May 2003

Prevalence and risk factors for sleep-disordered breathing in 8- to 11-year-old children: association with race and prematurity.

J Pediatr 2003 Apr;142(4):383-9

Department of Pediatrics, Rainbow Babies and Children's Hospital, Case Western Reserve University, Cleveland, Ohio 44106-6003, USA.

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http://dx.doi.org/10.1067/mpd.2003.28DOI Listing
April 2003

A whole-genome scan for obstructive sleep apnea and obesity.

Am J Hum Genet 2003 Feb 23;72(2):340-50. Epub 2002 Dec 23.

Channing Laboratory, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA.

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http://dx.doi.org/10.1086/346064DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC379227PMC
February 2003

Health-related quality of life and sleep-disordered breathing in children.

Sleep 2002 Sep;25(6):657-66

Department of Pediatrics, Rainbow Babies & Children's Hospital, Case Western Reserve University School of Medicine, Cleveland, OH 44106-6003, USA.

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September 2002

Utility of noninvasive pharyngometry in epidemiologic studies of childhood sleep-disordered breathing.

Am J Respir Crit Care Med 2002 Jun;165(11):1499-503

Department of Internal Medicine, Case Western Reserve University, University Hospitals of Cleveland, OH, USA.

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http://dx.doi.org/10.1164/rccm.200111-061OCDOI Listing
June 2002