Emma J Crosbie

Emma J Crosbie

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Emma J Crosbie

Emma J Crosbie

Publications by authors named "Emma J Crosbie"

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Cancer risks by gene, age, and gender in 6350 carriers of pathogenic mismatch repair variants: findings from the Prospective Lynch Syndrome Database.

Genet Med 2019 Jul 24. Epub 2019 Jul 24.

Department of Tumor Biology, Institute of Cancer Research, The Norwegian Radium Hospital, Oslo University Hospital, Oslo, Norway.

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http://dx.doi.org/10.1038/s41436-019-0596-9DOI Listing
July 2019

Prevalence of germline pathogenic variants in sequential epithelial ovarian cancer cases.

J Med Genet 2019 May 25;56(5):301-307. Epub 2019 Jan 25.

Manchester Centre for Genomic Medicine, St Mary's Hospital, Manchester University NHS Foundation Trust, Manchester, UK.

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http://dx.doi.org/10.1136/jmedgenet-2018-105792DOI Listing
May 2019

Targeting Endometrial Cancer Stem Cell Activity with Metformin Is Inhibited by Patient-Derived Adipocyte-Secreted Factors.

Cancers (Basel) 2019 May 11;11(5). Epub 2019 May 11.

Division of Cancer Sciences, Faculty of Biology, Medicine and Health, University of Manchester, St Mary's Hospital, Manchester M13 9WL, UK.

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http://dx.doi.org/10.3390/cancers11050653DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6562824PMC
May 2019

Epithelial ovarian cancer risk: A review of the current genetic landscape.

Clin Genet 2019 May 16. Epub 2019 May 16.

Division of Evolution and Genomic Sciences, School of Biological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Manchester, UK.

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http://dx.doi.org/10.1111/cge.13566DOI Listing
May 2019

Optimization of Window Study Endpoints in Endometrial Cancer.

Front Oncol 2019 29;9:428. Epub 2019 May 29.

Division of Cancer Sciences, Faculty of Biology, Medicine and Health, University of Manchester, St. Mary's Hospital, Manchester, United Kingdom.

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http://dx.doi.org/10.3389/fonc.2019.00428DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6554675PMC
May 2019

Lack of association between screening interval and cancer stage in Lynch syndrome may be accounted for by over-diagnosis; a prospective Lynch syndrome database report.

Hered Cancer Clin Pract 2019 28;17. Epub 2019 Feb 28.

4Department of Tumor Biology, Institute of Cancer Research, The Norwegian Radium Hospital, part of Oslo University Hospital, Olso, Norway.

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https://hccpjournal.biomedcentral.com/articles/10.1186/s1305
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http://dx.doi.org/10.1186/s13053-019-0106-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6394091PMC
February 2019

A Micro-Costing Study of Screening for Lynch Syndrome-Associated Pathogenic Variants in an Unselected Endometrial Cancer Population: Cheap as NGS Chips?

Front Oncol 2019 26;9:61. Epub 2019 Feb 26.

Gynaecological Oncology Research Group, Division of Cancer Sciences, School of Medical Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, United Kingdom.

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http://dx.doi.org/10.3389/fonc.2019.00061DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6399107PMC
February 2019

Prevention Strategies in Endometrial Carcinoma.

Curr Oncol Rep 2018 11 13;20(12):101. Epub 2018 Nov 13.

Department of Obstetrics and Gynaecology, St Mary's Hospital, Manchester Academic Health Science Centre, Manchester University NHS Foundation Trust, Manchester, UK.

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http://link.springer.com/10.1007/s11912-018-0747-1
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http://dx.doi.org/10.1007/s11912-018-0747-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6244901PMC
November 2018

High prevalence of metabolic syndrome in women newly diagnosed with endometrial cancer.

Gynecol Oncol Rep 2018 Nov 23;26:109-110. Epub 2018 Aug 23.

Division of Cancer Sciences, Faculty of Biology, Medicine and Health, University of Manchester, St Mary's Hospital, Manchester M13 9WL, UK.

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http://dx.doi.org/10.1016/j.gore.2018.08.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6262224PMC
November 2018

The prevalence of Lynch syndrome in women with endometrial cancer: a systematic review protocol.

Syst Rev 2018 08 16;7(1):121. Epub 2018 Aug 16.

Division of Cancer Sciences, Faculty of Biology, Medicine and Health, University of Manchester, St Mary's Hospital, Manchester, UK.

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http://dx.doi.org/10.1186/s13643-018-0792-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6097297PMC
August 2018

Findings Linking Mismatch Repair Mutation With Age at Endometrial and Ovarian Cancer Onset in Lynch Syndrome-Reply.

JAMA Oncol 2018 Jun;4(6):890-891

Division of Evolution and Genomic Medicine, Faculty of Biology, Medicine and Health, University of Manchester, St Mary's Hospital, Manchester, England.

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http://dx.doi.org/10.1001/jamaoncol.2018.0280DOI Listing
June 2018

Pir2/Rnf144b is a potential endometrial cancer biomarker that promotes cell proliferation.

Cell Death Dis 2018 05 1;9(5):504. Epub 2018 May 1.

University of Manchester, Faculty of Medical and Human Sciences, Division of Cancer Sciences, Manchester Cancer Research Centre, Wilmslow Road, Manchester, M20 4QL, UK.

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http://dx.doi.org/10.1038/s41419-018-0521-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5938710PMC
May 2018

Recognizing Gynecological Cancer in Primary Care: Risk Factors, Red Flags, and Referrals.

Adv Ther 2018 04 7;35(4):577-589. Epub 2018 Mar 7.

Gynaecological Oncology Group, University of Manchester, Manchester, UK.

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http://dx.doi.org/10.1007/s12325-018-0683-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5910472PMC
April 2018

Interventions for weight reduction in obesity to improve survival in women with endometrial cancer.

Cochrane Database Syst Rev 2018 02 1;2:CD012513. Epub 2018 Feb 1.

Division of Cancer Sciences, Faculty of Biology, Medicine and Health, University of Manchester, 5th Floor - Research, St Mary's Hospital, Manchester, UK, M13 9WL.

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http://dx.doi.org/10.1002/14651858.CD012513.pub2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6491136PMC
February 2018

Intraoperative interventions for preventing surgical site infection: an overview of Cochrane Reviews.

Cochrane Database Syst Rev 2018 02 6;2:CD012653. Epub 2018 Feb 6.

Division of Nursing, Midwifery and Social Work, School of Health Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Jean McFarlane Building, Oxford Road, Manchester, UK, M13 9PL.

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http://dx.doi.org/10.1002/14651858.CD012653.pub2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6491077PMC
February 2018

The unrecognized burden of cardiovascular risk factors in women newly diagnosed with endometrial cancer: A prospective case control study.

Gynecol Oncol 2018 01 24;148(1):154-160. Epub 2017 Nov 24.

Division of Cancer Sciences, Faculty of Biology, Medicine and Health, University of Manchester, St Mary's Hospital, Manchester M13 9WL, United Kingdom; Department of Obstetrics and Gynaecology, Manchester University NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester M13 9WL, United Kingdom. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00908258173152
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http://dx.doi.org/10.1016/j.ygyno.2017.11.019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6562057PMC
January 2018

Human papillomavirus E7 induces p63 expression to modulate DNA damage response.

Cell Death Dis 2018 01 26;9(2):127. Epub 2018 Jan 26.

Division of Cancer Sciences, School of Medical Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Manchester Cancer Research Centre, Wilmslow Road, Manchester, M20 4QL, UK.

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http://dx.doi.org/10.1038/s41419-017-0149-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833683PMC
January 2018

Monocarboxylate Transporter 1 (MCT1) is an independent prognostic biomarker in endometrial cancer.

BMC Clin Pathol 2017 28;17:27. Epub 2017 Dec 28.

Gynaecological Oncology Research Group, Division of Cancer Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Level 5 - Research, St Mary's Hospital, Oxford Road, Manchester, M13 9WL UK.

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http://dx.doi.org/10.1186/s12907-017-0067-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5745908PMC
December 2017

BRCA and lynch syndrome-associated ovarian cancers behave differently.

Gynecol Oncol Rep 2017 Nov 22;22:108-109. Epub 2017 Nov 22.

Division of Cancer Sciences, Faculty of Biology, Medicine and Health, University of Manchester, St Mary's Hospital, Manchester, UK.

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http://dx.doi.org/10.1016/j.gore.2017.11.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5705797PMC
November 2017

Intracavity lavage and wound irrigation for prevention of surgical site infection.

Cochrane Database Syst Rev 2017 10 30;10:CD012234. Epub 2017 Oct 30.

Division of Nursing, Midwifery & Social Work, School of Health Sciences, Faculty of Biology, Medicine & Health, University of Manchester, Manchester Academic Health Science Centre, Jean McFarlane Building, Oxford Road, Manchester, UK, M13 9PL.

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http://dx.doi.org/10.1002/14651858.CD012234.pub2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5686649PMC
October 2017

Nasal decontamination for the prevention of surgical site infection in Staphylococcus aureus carriers.

Cochrane Database Syst Rev 2017 05 18;5:CD012462. Epub 2017 May 18.

Clinical Microbiology and Virology, University College London Hospitals NHS Foundation Trust, 60 Whitfield Street, London, UK, W1T 4EU.

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http://doi.wiley.com/10.1002/14651858.CD012462.pub2
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http://dx.doi.org/10.1002/14651858.CD012462.pub2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6481881PMC
May 2017

Ki-67 in endometrial cancer: scoring optimization and prognostic relevance for window studies.

Mod Pathol 2017 03 2;30(3):459-468. Epub 2016 Dec 2.

Division of Molecular and Clinical Cancer Sciences, Faculty of Biology, Medicine and Health, University of Manchester, St Mary's Hospital, Manchester, UK.

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http://dx.doi.org/10.1038/modpathol.2016.203DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5337118PMC
March 2017

Urocortin suppresses endometrial cancer cell migration via CRFR2 and its system components are differentially modulated by estrogen.

Cancer Med 2017 02 21;6(2):408-415. Epub 2017 Jan 21.

Division of Molecular & Clinical Cancer Sciences, School of Medical Sciences, Faculty of Biology, Medicine & Health, Manchester Cancer Research Centre, University of Manchester, Wilmslow Road, Manchester, M20 4QL, United Kingdom.

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http://dx.doi.org/10.1002/cam4.967DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5313640PMC
February 2017

Novel risk models for early detection and screening of ovarian cancer.

Oncotarget 2017 Jan;8(1):785-797

Stoller Biomarker Discovery Centre and Pathology Node, Division of Molecular and Clinical Cancer Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK.

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http://dx.doi.org/10.18632/oncotarget.13648DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5352196PMC
January 2017

Identifying High-Risk Women for Endometrial Cancer Prevention Strategies: Proposal of an Endometrial Cancer Risk Prediction Model.

Cancer Prev Res (Phila) 2017 Jan 13;10(1):1-13. Epub 2016 Dec 13.

Division of Molecular and Clinical Cancer Sciences, Faculty of Biology, Medicine and Health, University of Manchester, St Mary's Hospital, Manchester, United Kingdom.

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http://dx.doi.org/10.1158/1940-6207.CAPR-16-0224DOI Listing
January 2017

Antiseptics and Antibiotics for Surgical Wounds Healing by Secondary Intention: Summary of a Cochrane Review.

JAMA Dermatol 2016 11;152(11):1266-1268

Institute of Cancer Sciences, Faculty of Biology, Medicine and Health, University of Manchester, St Mary's Hospital, Manchester, England3Department of Obstetrics and Gynaecology, Central Manchester University Hospitals NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, England.

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http://dx.doi.org/10.1001/jamadermatol.2016.3131DOI Listing
November 2016

Working together to shape the endometrial cancer research agenda: The top ten unanswered research questions.

Gynecol Oncol 2016 Nov 1;143(2):287-293. Epub 2016 Sep 1.

Gynaecological Oncology Research Group, Institute of Cancer Sciences, Faculty of Medical and Human Sciences, University of Manchester, St Mary's Hospital, Oxford Road, Manchester M13 9WL, UK; Womb Cancer Alliance Priority Setting Partnership Study Group, UK. Electronic address:

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http://dx.doi.org/10.1016/j.ygyno.2016.08.333DOI Listing
November 2016

A prospective study of anal cancer screening in HIV-positive and negative MSM.

AIDS 2016 06;30(9):1375-83

aInstitute of Cancer Sciences, The University of Manchester bCentre for Biostatistics, Institute of Population Health, The University of Manchester cManchester Cytology Centre, Central Manchester University Hospitals NHS Foundation Trust, Manchester dClinical Virology, Central Manchester University Hospitals NHS Foundation Trust, Manchester eDepartment of Histopathology, Central Manchester University Hospitals NHS Foundation Trust, Manchester fGeneral Surgery, Central Manchester University Hospitals NHS Foundation Trust, Manchester gPublic Health England, Sheffield, UK.

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http://dx.doi.org/10.1097/QAD.0000000000001045DOI Listing
June 2016

Antibiotics and antiseptics for surgical wounds healing by secondary intention.

Cochrane Database Syst Rev 2016 Mar 29;3:CD011712. Epub 2016 Mar 29.

School of Nursing, Midwifery and Social Work, University of Manchester, Jean McFarlane Building, Oxford Road, Manchester, UK, M13 9PL.

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http://dx.doi.org/10.1002/14651858.CD011712.pub2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6599835PMC
March 2016

ERK and AKT phosphorylation status in lung cancer and emphysema using nanocapillary isoelectric focusing.

BMJ Open Respir Res 2016 17;3(1):e000114. Epub 2016 Feb 17.

Stem Cell and Leukaemia Proteomics Laboratory , University of Manchester, Manchester Academic Health Science Centre , Manchester , UK.

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http://dx.doi.org/10.1136/bmjresp-2015-000114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4762086PMC
February 2016

The PapilloCheck Assay for Detection of High-Grade Cervical Intraepithelial Neoplasia.

J Clin Microbiol 2015 Nov 2;53(11):3553-9. Epub 2015 Sep 2.

Institute of Cancer Sciences, University of Manchester, St. Mary's Hospital, Manchester, United Kingdom.

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http://dx.doi.org/10.1128/JCM.01578-15DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4609672PMC
November 2015

Negative pressure wound therapy for treating surgical wounds healing by secondary intention.

Cochrane Database Syst Rev 2015 Jun 4(6):CD011278. Epub 2015 Jun 4.

School of Nursing, Midwifery and Social Work, University of Manchester, Manchester, UK, M13 9PL.

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http://doi.wiley.com/10.1002/14651858.CD011278.pub2
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http://dx.doi.org/10.1002/14651858.CD011278.pub2DOI Listing
June 2015

Metformin in reproductive health, pregnancy and gynaecological cancer: established and emerging indications.

Hum Reprod Update 2014 Nov-Dec;20(6):853-68. Epub 2014 Jul 10.

Institute of Cancer Sciences, Manchester Academic Health Science Centre, University of Manchester, Central Manchester University Hospitals NHS Foundation Trust, Oxford Road, Manchester M13 9WL, UK

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http://dx.doi.org/10.1093/humupd/dmu037DOI Listing
May 2015

Re: Prediagnosis body mass index, physical activity, and mortality in endometrial cancer patients.

J Natl Cancer Inst 2014 Feb 4;106(2):djt375. Epub 2014 Jan 4.

Affiliations of authors: Diabetes Obesity and Cancer Research Group (AGR) and Women's Cancer Centre, Institute of Cancer Sciences, University of Manchester, Manchester, UK (EJC); Epidemiology Research Program, American Cancer Society, National Home Office, Atlanta, GA (PTC).

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http://dx.doi.org/10.1093/jnci/djt375DOI Listing
February 2014

Prophylactic pre-operative bilateral ureteric catheters for major gynaecological surgery.

Arch Gynecol Obstet 2013 Nov 25;288(5):1061-6. Epub 2013 Apr 25.

Department of Obstetrics and Gynaecology, Salford Royal Hospitals NHS Trust, Salford, UK.

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http://dx.doi.org/10.1007/s00404-013-2853-5DOI Listing
November 2013

Human papillomavirus and cervical cancer.

Lancet 2013 Sep 23;382(9895):889-99. Epub 2013 Apr 23.

Institute of Cancer Sciences, University of Manchester, Oxford Road, Manchester, UK.

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http://dx.doi.org/10.1016/S0140-6736(13)60022-7DOI Listing
September 2013

Developing role of HPV in cervical cancer prevention.

BMJ 2013 Aug 7;347:f4781. Epub 2013 Aug 7.

Institute of Cancer Sciences, University of Manchester, St Mary's Hospital, Manchester M13 9WL, UK.

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http://dx.doi.org/10.1136/bmj.f4781DOI Listing
August 2013

Human papillomavirus as a target for management, prevention and therapy.

Int J Hyperthermia 2012 12;28(6):478-88. Epub 2012 Jun 12.

Academic Unit of Obstetrics and Gynaecology, University of Manchester, St Mary's Hospital, Manchester, UK.

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http://dx.doi.org/10.3109/02656736.2012.677934DOI Listing
January 2013

Body mass index does not influence post-treatment survival in early stage endometrial cancer: results from the MRC ASTEC trial.

Eur J Cancer 2012 Apr 17;48(6):853-64. Epub 2011 Nov 17.

Gynaecology Oncology Research Group, School of Cancer and Enabling Sciences, University of Manchester, Manchester, UK.

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http://dx.doi.org/10.1016/j.ejca.2011.10.003DOI Listing
April 2012

The surgical rectus sheath block for post-operative analgesia: a modern approach to an established technique.

Eur J Obstet Gynecol Reprod Biol 2012 Feb 21;160(2):196-200. Epub 2011 Nov 21.

Academic Unit of Obstetrics & Gynaecology, St Mary's Hospital, Hathersage Road, Manchester M13 9WL, United Kingdom.

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http://dx.doi.org/10.1016/j.ejogrb.2011.10.015DOI Listing
February 2012

Apronectomy combined with laparotomy for morbidly obese endometrial cancer patients.

Surg Oncol 2011 Dec 29;20(4):e187-93. Epub 2011 Jul 29.

Department of Gynaecological Oncology, The Christie NHS Foundation Trust, Wilmslow Road, Manchester M20 4BX, UK.

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http://dx.doi.org/10.1016/j.suronc.2011.06.005DOI Listing
December 2011

The accuracy of the sentinel node procedure after excision biopsy in squamous cell carcinoma of the vulva.

Surg Oncol 2010 Dec 15;19(4):e150-4. Epub 2010 Sep 15.

Department of Gynaecological Oncology, The Christie NHS Foundation Trust, Manchester, UK.

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http://dx.doi.org/10.1016/j.suronc.2010.08.003DOI Listing
December 2010

Body mass index, hormone replacement therapy, and endometrial cancer risk: a meta-analysis.

Cancer Epidemiol Biomarkers Prev 2010 Dec 28;19(12):3119-30. Epub 2010 Oct 28.

Gynaecology Oncology Research Group, School of Cancer and Enabling Sciences, University of Manchester, Manchester, UK.

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http://cebp.aacrjournals.org/cgi/doi/10.1158/1055-9965.EPI-1
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http://dx.doi.org/10.1158/1055-9965.EPI-10-0832DOI Listing
December 2010

The management of vulval cancer.

Cancer Treat Rev 2009 Nov 20;35(7):533-9. Epub 2009 Aug 20.

The Christie NHS Foundation Trust, Wilmslow Road, Manchester, M20 4BX, United Kingdom.

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http://linkinghub.elsevier.com/retrieve/pii/S030573720900018
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http://dx.doi.org/10.1016/j.ctrv.2009.01.005DOI Listing
November 2009

Cervarix--a bivalent L1 virus-like particle vaccine for prevention of human papillomavirus type 16- and 18-associated cervical cancer.

Expert Opin Biol Ther 2007 Mar;7(3):391-6

University of Manchester, Academic Unit of Obstetrics and Gynaecology, St Mary's Hospital, Whitworth Park, Manchester, M13 0JH, UK.

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http://dx.doi.org/10.1517/14712598.7.3.391 DOI Listing
March 2007

Human papillomavirus in cervical screening and vaccination.

Clin Sci (Lond) 2006 May;110(5):543-52

Academic Unit of Obstetrics and Gynaecology, University of Manchester, St Mary's Hospital, Whitworth Park, Manchester M13 0JH, UK.

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http://dx.doi.org/10.1042/CS20050230DOI Listing
May 2006