Publications by authors named "Emma Gostick"

100Publications

The TLR9 ligand CpG ODN 2006 is a poor adjuvant for the induction of de novo CD8 T-cell responses in vitro.

Sci Rep 2020 07 15;10(1):11620. Epub 2020 Jul 15.

Centre d'Immunologie et des Maladies Infectieuses, Sorbonne Université, Institut National de la Santé et de la Recherche Médicale, 75013, Paris, France.

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http://dx.doi.org/10.1038/s41598-020-67704-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7363897PMC
July 2020

Activating PIK3CD mutations impair human cytotoxic lymphocyte differentiation and function and EBV immunity.

J Allergy Clin Immunol 2019 01 22;143(1):276-291.e6. Epub 2018 May 22.

Immunology Division, Garvan Institute of Medical Research, Darlinghurst, Australia; St Vincent's Clinical School, Faculty of Medicine, University of New South Wales Sydney, Darlinghurst, Australia; CIRCA (Clinical Immunogenomics Consortia Australia), Sydney, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2018.04.030DOI Listing
January 2019

Cutting Edge: A Dual TLR2 and TLR7 Ligand Induces Highly Potent Humoral and Cell-Mediated Immune Responses.

J Immunol 2017 06 21;198(11):4205-4209. Epub 2017 Apr 21.

Groupe Immunité des Muqueuses et Agents Pathogènes, Faculté de Médecine de Saint-Etienne, INSERM Centre d'Investigation Clinique en Vaccinologie 1408, 42023 Saint-Etienne, France;

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http://dx.doi.org/10.4049/jimmunol.1602131DOI Listing
June 2017

Priming of Qualitatively Superior Human Effector CD8+ T Cells Using TLR8 Ligand Combined with FLT3 Ligand.

J Immunol 2016 Jan 25;196(1):256-263. Epub 2015 Nov 25.

Sorbonne Universités, UPMC Univ Paris 06, DHU FAST, CR7, Centre d'Immunologie et des Maladies Infectieuses (CIMI-Paris), Paris, France.

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http://www.jimmunol.org/content/early/2015/11/25/jimmunol.15
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http://www.jimmunol.org/cgi/doi/10.4049/jimmunol.1501140
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http://dx.doi.org/10.4049/jimmunol.1501140DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4685747PMC
January 2016

Reduced naïve CD8(+) T-cell priming efficacy in elderly adults.

Aging Cell 2016 Feb 15;15(1):14-21. Epub 2015 Oct 15.

Centre d'Immunologie et des Maladies Infectieuses (CIMI-Paris), Sorbonne Universités, UPMC Univ Paris 06, DHU FAST, CR7, F-75013, Paris, France.

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http://dx.doi.org/10.1111/acel.12384DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4717282PMC
February 2016

Expansion of Simian Immunodeficiency Virus (SIV)-Specific CD8 T Cell Lines from SIV-Naive Mauritian Cynomolgus Macaques for Adoptive Transfer.

J Virol 2015 Oct 15;89(19):9748-57. Epub 2015 Jul 15.

Department of Pathology, University of Wisconsin-Madison, Madison, Wisconsin, USA Wisconsin National Primate Research Center, University of Wisconsin-Madison, Madison, Wisconsin, USA

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http://dx.doi.org/10.1128/JVI.00993-15DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4577914PMC
October 2015

Erratum for O'Connor et al., Peptide-Dependent Recognition of HLA-B*57:01 by KIR3DS1.

J Virol 2015 Jul;89(14):7442

Cancer and Inflammation Program, Center for Cancer Research, National Cancer Institute, Frederick, Maryland, USA.

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http://dx.doi.org/10.1128/JVI.01159-15DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4473542PMC
July 2015

Elevated Expression of CD160 and 2B4 Defines a Cytolytic HIV-Specific CD8+ T-Cell Population in Elite Controllers.

J Infect Dis 2015 Nov 15;212(9):1376-86. Epub 2015 Apr 15.

Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia.

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http://dx.doi.org/10.1093/infdis/jiv226DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4601914PMC
November 2015

Naive CD8⁺ T-cell precursors display structured TCR repertoires and composite antigen-driven selection dynamics.

Immunol Cell Biol 2015 Aug 24;93(7):625-33. Epub 2015 Mar 24.

1] Human Immunity Laboratory, Cellular Immunology Laboratory and Tumour Immunology Laboratory, Queensland Institute of Medical Research, Brisbane, QLD, Australia [2] Institute of Infection and Immunity, Cardiff University School of Medicine, Heath Park, Cardiff, UK [3] School of Medicine, The University of Queensland, Brisbane, QLD, Australia.

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http://dx.doi.org/10.1038/icb.2015.17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4533101PMC
August 2015

Peptide-Dependent Recognition of HLA-B*57:01 by KIR3DS1.

J Virol 2015 May 4;89(10):5213-21. Epub 2015 Mar 4.

Cancer and Inflammation Program, Center for Cancer Research, National Cancer Institute, Frederick, Maryland, USA

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http://dx.doi.org/10.1128/JVI.03586-14DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4442525PMC
May 2015

The link between CD8⁺ T-cell antigen-sensitivity and HIV-suppressive capacity depends on HLA restriction, target epitope and viral isolate.

AIDS 2014 Feb;28(4):477-86

aINSERM UMR S 945, Infections and Immunity, Université Pierre et Marie Curie-Paris6, Hôpital Pitié-Salpêtrière, Paris, France bInstitute of Infection and Immunity, Cardiff University School of Medicine, Heath Park, Cardiff, Wales, UK cInstitut Pasteur, Unité de Régulation des Infections Rétrovirales, Paris, France. *Anna Lissina and Solène Fastenackels contributed equally to this writing of this work. †Current address: Centro de Investigacion en Enfermedades Infecciosas, Instituto Nacional de Enfermedades Respiratorias, Mexico City, Mexico.

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http://dx.doi.org/10.1097/QAD.0000000000000175DOI Listing
February 2014

Heterosubtypic cross-protection induced by whole inactivated influenza virus vaccine in mice: influence of the route of vaccine administration.

Influenza Other Respir Viruses 2013 Nov 16;7(6):1202-9. Epub 2013 Sep 16.

Department of Medical Microbiology, Molecular Virology Section, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.

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http://dx.doi.org/10.1111/irv.12142DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4112805PMC
November 2013

Immunodominance and functional alterations of tumor-associated antigen-specific CD8+ T-cell responses in hepatocellular carcinoma.

Hepatology 2014 Apr 20;59(4):1415-26. Epub 2014 Feb 20.

Department of Internal Medicine II, University Hospital Freiburg, Freiburg, Germany; Spemann Graduate School of Biology and Medicine (SGBM), Albert-Ludwigs-University, Freiburg, Germany; Faculty of Biology, Albert-Ludwigs-University, Freiburg, Germany.

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http://dx.doi.org/10.1002/hep.26731DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4139003PMC
April 2014

Critical role of TLR7 signaling in the priming of cross-protective cytotoxic T lymphocyte responses by a whole inactivated influenza virus vaccine.

PLoS One 2013 2;8(5):e63163. Epub 2013 May 2.

Molecular Virology Section, Department of Medical Microbiology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0063163PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3642048PMC
December 2013

CMV driven CD8(+) T-cell activation is associated with acute rejection in lung transplantation.

Clin Immunol 2013 Jul 29;148(1):16-26. Epub 2013 Mar 29.

INSERM UMR S 945, Infections and Immunity, Université Pierre et Marie Curie-Paris6, Hôpital Pitié-Salpêtrière, 75013 Paris, France.

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http://dx.doi.org/10.1016/j.clim.2013.03.012DOI Listing
July 2013

Holoendemic malaria exposure is associated with altered Epstein-Barr virus-specific CD8(+) T-cell differentiation.

J Virol 2013 Feb 21;87(3):1779-88. Epub 2012 Nov 21.

Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA.

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http://dx.doi.org/10.1128/JVI.02158-12DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3554182PMC
February 2013

Immunodominance of HLA-B27-restricted HIV KK10-specific CD8(+) T-cells is not related to naïve precursor frequency.

Immunol Lett 2013 Jan 13;149(1-2):119-22. Epub 2012 Oct 13.

INSERM UMR S 945, Infections and Immunity, Université Pierre et Marie Curie-Paris 6, Hôpital Pitié-Salpêtrière, Paris, France.

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http://dx.doi.org/10.1016/j.imlet.2012.10.002DOI Listing
January 2013

Degenerate recognition of MHC class I molecules with Bw4 and Bw6 motifs by a killer cell Ig-like receptor 3DL expressed by macaque NK cells.

J Immunol 2012 Nov 5;189(9):4338-48. Epub 2012 Oct 5.

Non-Human Primate Immunogenetics and Cellular Immunology Unit, Laboratory of Molecular Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.4049/jimmunol.1201360DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3507536PMC
November 2012

Type I IFN induced by adenovirus serotypes 28 and 35 has multiple effects on T cell immunogenicity.

J Immunol 2012 Jun 14;188(12):6109-18. Epub 2012 May 14.

Immunology Laboratory, Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.4049/jimmunol.1103717DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3370104PMC
June 2012

Neonatal CD8 T-cell hierarchy is distinct from adults and is influenced by intrinsic T cell properties in respiratory syncytial virus infected mice.

PLoS Pathog 2011 Dec 1;7(12):e1002377. Epub 2011 Dec 1.

Vaccine Research Center, National Institute of Allergy and Infectious Disease, National Institutes of Health, Bethesda, Maryland, United States of America.

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http://dx.plos.org/10.1371/journal.ppat.1002377
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http://dx.doi.org/10.1371/journal.ppat.1002377DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3228797PMC
December 2011

Structural basis of diverse peptide accommodation by the rhesus macaque MHC class I molecule Mamu-B*17: insights into immune protection from simian immunodeficiency virus.

J Immunol 2011 Dec 14;187(12):6382-92. Epub 2011 Nov 14.

CAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101, The People's Republic of China.

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http://dx.doi.org/10.4049/jimmunol.1101726DOI Listing
December 2011

A human memory T cell subset with stem cell-like properties.

Nat Med 2011 Sep 18;17(10):1290-7. Epub 2011 Sep 18.

Center for Cancer Research, National Cancer Institute, US National Institutes of Health (NIH), Bethesda, Maryland, USA.

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http://dx.doi.org/10.1038/nm.2446DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3192229PMC
September 2011

Biphasic role of 4-1BB in the regulation of mouse cytomegalovirus-specific CD8(+) T cells.

Eur J Immunol 2010 Oct;40(10):2762-8

Division of Molecular Immunology, La Jolla Institute for Allergy and Immunology, La Jolla, CA, USA.

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http://dx.doi.org/10.1002/eji.200940256DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2967573PMC
October 2010

IL-10 restricts memory T cell inflation during cytomegalovirus infection.

J Immunol 2010 Sep 16;185(6):3583-92. Epub 2010 Aug 16.

Department of Infection, Immunity and Biochemistry, School of Medicine, Cardiff University, Cardiff, United Kingdom.

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http://www.jimmunol.org/cgi/doi/10.4049/jimmunol.1001535
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http://dx.doi.org/10.4049/jimmunol.1001535DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3655265PMC
September 2010

Germ line-governed recognition of a cancer epitope by an immunodominant human T-cell receptor.

J Biol Chem 2009 Oct 15;284(40):27281-9. Epub 2009 Jul 15.

Department of Infection, Immunity, and Biochemistry, Henry Wellcome Building, Cardiff University School of Medicine, Heath Park, Cardiff CF14 4XN, United Kingdom.

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http://dx.doi.org/10.1074/jbc.M109.022509DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2785656PMC
October 2009

Public clonotype usage identifies protective Gag-specific CD8+ T cell responses in SIV infection.

J Exp Med 2009 Apr 6;206(4):923-36. Epub 2009 Apr 6.

Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1084/jem.20081127DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2715115PMC
April 2009

Techniques to improve the direct ex vivo detection of low frequency antigen-specific CD8+ T cells with peptide-major histocompatibility complex class I tetramers.

Cytometry A 2008 Nov;73(11):1001-9

Immunotechnology Section, Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA.

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http://dx.doi.org/10.1002/cyto.a.20642DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2586006PMC
November 2008

The cytolytic enzymes granyzme A, granzyme B, and perforin: expression patterns, cell distribution, and their relationship to cell maturity and bright CD57 expression.

J Leukoc Biol 2009 Jan 10;85(1):88-97. Epub 2008 Oct 10.

ImmunoTechnology Section, Laboratory of Immunology, Vaccine Research Center, National Institutes of Health, Bethesda, MD, USA.

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http://dx.doi.org/10.1189/jlb.0208107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2638730PMC
January 2009

Functional restoration of HCV-specific CD8 T cells by PD-1 blockade is defined by PD-1 expression and compartmentalization.

Gastroenterology 2008 Jun 17;134(7):1927-37, 1937.e1-2. Epub 2008 Feb 17.

Division of Gastroenterology, Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA.

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http://dx.doi.org/10.1053/j.gastro.2008.02.033DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2665722PMC
June 2008

Profound inhibition of antigen-specific T-cell effector functions by dasatinib.

Clin Cancer Res 2008 Apr;14(8):2484-91

Immune Recovery Section, Med. Klinik und Poliklinik II, University of Würzburg, Würzburg, Germany.

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http://dx.doi.org/10.1158/1078-0432.CCR-07-4393DOI Listing
April 2008