Emily M LeProust

Emily M LeProust

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Emily M LeProust

Emily M LeProust

Publications by authors named "Emily M LeProust"

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24Publications

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Structure-guided SCHEMA recombination generates diverse chimeric channelrhodopsins.

Proc Natl Acad Sci U S A 2017 03 10;114(13):E2624-E2633. Epub 2017 Mar 10.

Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125;

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http://dx.doi.org/10.1073/pnas.1700269114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5380088PMC
March 2017

Utilizing ethnic-specific differences in minor allele frequency to recategorize reported pathogenic deafness variants.

Am J Hum Genet 2014 Oct 25;95(4):445-53. Epub 2014 Sep 25.

Molecular Otolaryngology & Renal Research Labs, Department of Otolaryngology-Head and Neck Surgery, University of Iowa Carver College of Medicine, Iowa City, IA 52242, USA; Interdepartmental PhD Program in Genetics, University of Iowa, Iowa City, IA 52242, USA; Department of Molecular Physiology & Biophysics, University of Iowa Carver College of Medicine, Iowa City, IA 52242, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ajhg.2014.09.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4185121PMC
October 2014

Systematic identification of barriers to human iPSC generation.

Cell 2014 Jul;158(2):449-461

Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, University of California, San Francisco, San Francisco, CA 94143, USA; Departments of Ob/Gyn and Pathology, Center for Reproductive Sciences, and Diabetes Center, University of California, San Francisco, San Francisco, CA 94143, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2014.05.040DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4130998PMC
July 2014

Towards practical, high-capacity, low-maintenance information storage in synthesized DNA.

Nature 2013 Feb 23;494(7435):77-80. Epub 2013 Jan 23.

European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton CB10 1SD, UK.

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http://dx.doi.org/10.1038/nature11875DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3672958PMC
February 2013

A systematic mammalian genetic interaction map reveals pathways underlying ricin susceptibility.

Cell 2013 Feb 8;152(4):909-22. Epub 2013 Feb 8.

Department of Cellular and Molecular Pharmacology, California Institute for Quantitative Biomedical Research and Howard Hughes Medical Institute, University of California, San Francisco, San Francisco, CA 94122, USA.

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http://dx.doi.org/10.1016/j.cell.2013.01.030DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3652613PMC
February 2013

Pre-capture multiplexing improves efficiency and cost-effectiveness of targeted genomic enrichment.

BMC Genomics 2012 Nov 14;13:618. Epub 2012 Nov 14.

Department of Otolaryngology - Head & Neck Surgery, University of Iowa Carver College of Medicine, Iowa City, IA 52242, USA.

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http://bmcgenomics.biomedcentral.com/articles/10.1186/1471-2
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http://dx.doi.org/10.1186/1471-2164-13-618DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3534602PMC
November 2012

Efficient and cost effective population resequencing by pooling and in-solution hybridization.

PLoS One 2011 Mar 30;6(3):e18353. Epub 2011 Mar 30.

Scripps Genomic Medicine, Scripps Translational Science Institute, La Jolla, California, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0018353PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3068187PMC
March 2011

Scalable gene synthesis by selective amplification of DNA pools from high-fidelity microchips.

Nat Biotechnol 2010 Dec 28;28(12):1295-9. Epub 2010 Nov 28.

Wyss Institute for Biologically Inspired Engineering, Boston, Massachusetts, USA.

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http://www.nature.com/articles/nbt.1716
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http://dx.doi.org/10.1038/nbt.1716DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3139991PMC
December 2010

Temporal and spatial profile of brain diffusion-weighted MRI after cardiac arrest.

Stroke 2010 Aug 1;41(8):1665-72. Epub 2010 Jul 1.

Department of Neurology and Neurological Sciences, Stanford Stroke Center, Palo Alto, Calif 94304, USA.

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http://dx.doi.org/10.1161/STROKEAHA.110.582452DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2914620PMC
August 2010

Synthesis of high-quality libraries of long (150mer) oligonucleotides by a novel depurination controlled process.

Nucleic Acids Res 2010 May 22;38(8):2522-40. Epub 2010 Mar 22.

Agilent Technologies Inc., LSSU - Genomics, 5301 Stevens Creek Blvd, Santa Clara, CA 95051, USA.

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http://dx.doi.org/10.1093/nar/gkq163DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2860131PMC
May 2010

Enrichment of sequencing targets from the human genome by solution hybridization.

Genome Biol 2009 16;10(10):R116. Epub 2009 Oct 16.

Scripps Genomic Medicine, Scripps Translational Science Institute, The Scripps Research Institute, 3344 N Torrey Pines Court, La Jolla, CA 92037, USA.

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http://genomebiology.biomedcentral.com/articles/10.1186/gb-2
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http://dx.doi.org/10.1186/gb-2009-10-10-r116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2784331PMC
January 2010

Digital RNA allelotyping reveals tissue-specific and allele-specific gene expression in human.

Nat Methods 2009 Aug 20;6(8):613-8. Epub 2009 Jul 20.

Department of Bioengineering, University of California at San Diego, La Jolla, California, USA.

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http://dx.doi.org/10.1038/nmeth.1357DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2742772PMC
August 2009

Rapid creation and quantitative monitoring of high coverage shRNA libraries.

Nat Methods 2009 Jun 17;6(6):443-5. Epub 2009 May 17.

Department of Cellular and Molecular Pharmacology, California Institute for Quantitative Biomedical Research, Howard Hughes Medical Institute, University of California, San Francisco, California, USA.

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http://dx.doi.org/10.1038/nmeth.1330DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2783737PMC
June 2009

Targeted and genome-scale strategies reveal gene-body methylation signatures in human cells.

Nat Biotechnol 2009 Apr 29;27(4):361-8. Epub 2009 Mar 29.

Department of Genetics, Harvard Medical School, Cambridge, MA, USA.

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http://dx.doi.org/10.1038/nbt.1533DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3566772PMC
April 2009

The DNA-encoded nucleosome organization of a eukaryotic genome.

Nature 2009 Mar 17;458(7236):362-6. Epub 2008 Dec 17.

Department of Computer Science and Applied Mathematics, Weizmann Institute of Science, Rehovot 76100, Israel.

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http://dx.doi.org/10.1038/nature07667DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2658732PMC
March 2009