Publications by authors named "Emily Hams"

40Publications

Role for Retinoic Acid-Related Orphan Receptor Alpha (RORα) Expressing Macrophages in Diet-Induced Obesity.

Front Immunol 2020 27;11:1966. Epub 2020 Aug 27.

School of Medicine, Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin, Ireland.

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http://dx.doi.org/10.3389/fimmu.2020.01966DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7482427PMC
August 2020

Prostate cancer-derived holoclones: a novel and effective model for evaluating cancer stemness.

Sci Rep 2020 07 9;10(1):11329. Epub 2020 Jul 9.

Department of Histopathology and Morbid Anatomy, Trinity Translational Medicine Institute, Trinity College Dublin, Dublin, Ireland.

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http://dx.doi.org/10.1038/s41598-020-68187-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7347552PMC
July 2020

Correction to: Vascular endothelial growth factor is an autocrine growth factor, signaling through neuropilin-1 in non-small cell lung cancer.

Mol Cancer 2020 Jan 27;19(1):16. Epub 2020 Jan 27.

Thoracic Oncology Research Group, School of Clinical Medicine, Institute of Molecular Medicine, Trinity Centre for Health Sciences, St. James's Hospital & Trinity College Dublin, Dublin, Ireland.

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http://dx.doi.org/10.1186/s12943-020-1142-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6983966PMC
January 2020

Highly efficient CRISPR-targeting of the murine Hipp11 intergenic region supports inducible human transgene expression.

Mol Biol Rep 2020 Feb 6;47(2):1491-1498. Epub 2019 Dec 6.

School of Biochemistry& Immunology, Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin 2, Ireland.

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http://dx.doi.org/10.1007/s11033-019-05204-9DOI Listing
February 2020

Cell Survival and Cytokine Release after Inflammasome Activation Is Regulated by the Toll-IL-1R Protein SARM.

Immunity 2019 06 7;50(6):1412-1424.e6. Epub 2019 May 7.

School of Biochemistry and Immunology, Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin 2, Ireland. Electronic address:

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http://dx.doi.org/10.1016/j.immuni.2019.04.005DOI Listing
June 2019

Asymmetric synthesis and biological evaluation of imidazole- and oxazole-containing synthetic lipoxin A mimetics (sLXms).

Eur J Med Chem 2019 Jan 23;162:80-108. Epub 2018 Oct 23.

Centre for Synthesis and Chemical Biology, School of Chemistry, UCD Conway Institute, University College Dublin, Belfield, Dublin 4, Ireland. Electronic address:

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http://dx.doi.org/10.1016/j.ejmech.2018.10.049DOI Listing
January 2019

The vaccine adjuvant alum promotes IL-10 production that suppresses Th1 responses.

Eur J Immunol 2018 04 15;48(4):705-715. Epub 2018 Feb 15.

Adjuvant Research Group, School of Biochemistry and Immunology, Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin 2, Ireland.

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http://dx.doi.org/10.1002/eji.201747150DOI Listing
April 2018

Helminth Modulation of Lung Inflammation.

Trends Parasitol 2018 05 12;34(5):388-403. Epub 2018 Jan 12.

School of Medicine, Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin 2, Ireland. Electronic address:

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http://dx.doi.org/10.1016/j.pt.2017.12.007DOI Listing
May 2018

ILC2s regulate adaptive Th2 cell functions via PD-L1 checkpoint control.

J Exp Med 2017 Sep 26;214(9):2507-2521. Epub 2017 Jul 26.

Trinity Biomedical Sciences Institute, School of Medicine, Trinity College Dublin, Dublin, Ireland

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http://dx.doi.org/10.1084/jem.20170051DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5584124PMC
September 2017

Perinatal Activation of the Interleukin-33 Pathway Promotes Type 2 Immunity in the Developing Lung.

Immunity 2016 12 6;45(6):1285-1298. Epub 2016 Dec 6.

Department of Pulmonary Medicine, Erasmus University Medical Center Rotterdam, Rotterdam 3015 GJ, the Netherlands; Laboratory of Immunoregulation and Mucosal Immunology, VIB Inflammation Research Center, Ghent 9050, Belgium; Department of Pulmonary Medicine, Ghent University, Ghent 9000, Belgium. Electronic address:

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http://dx.doi.org/10.1016/j.immuni.2016.10.031DOI Listing
December 2016

Macrophage and Innate Lymphoid Cell Interplay in the Genesis of Fibrosis.

Front Immunol 2015 23;6:597. Epub 2015 Nov 23.

Trinity Biomedical Sciences Institute, School of Medicine, Trinity College Dublin , Dublin , Ireland.

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http://dx.doi.org/10.3389/fimmu.2015.00597DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4655423PMC
December 2015

The helminth T2 RNase ω1 promotes metabolic homeostasis in an IL-33- and group 2 innate lymphoid cell-dependent mechanism.

FASEB J 2016 Feb 21;30(2):824-35. Epub 2015 Oct 21.

*Trinity Biomedical Sciences Institute, School of Medicine, Trinity College Dublin, Dublin, Ireland; National Children's Research Centre, Our Lady's Children's Hospital, Dublin, Ireland; Obesity Immunology, Education and Research Centre, St. Vincent's University Hospital, University College Dublin, Dublin, Ireland; Department of Endocrinology, St. Vincent's University Hospital, Elm Park, Dublin, Ireland; Division of Cellular Immunology, German Cancer Research Center, Heidelberg, Germany; and Medical Research Council Laboratory of Molecular Biology, Cambridge, United Kingdom

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http://dx.doi.org/10.1096/fj.15-277822DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4973506PMC
February 2016

Spontaneous atopic dermatitis is mediated by innate immunity, with the secondary lung inflammation of the atopic march requiring adaptive immunity.

J Allergy Clin Immunol 2016 Feb 20;137(2):482-91. Epub 2015 Aug 20.

Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin, Ireland; National Children's Research Centre, Our Lady's Children's Hospital, Dublin, Ireland; Institute of Molecular Medicine, St James's Hospital, Dublin, Ireland. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2015.06.045DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4735016PMC
February 2016

Vascular endothelial growth factor is an autocrine growth factor, signaling through neuropilin-1 in non-small cell lung cancer.

Mol Cancer 2015 Feb 20;14:45. Epub 2015 Feb 20.

Thoracic Oncology Research Group, School of Clinical Medicine, Institute of Molecular Medicine, Trinity Centre for Health Sciences, St. James's Hospital & Trinity College Dublin, Dublin, Ireland.

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http://www.brimr.org/Reprints/135.pdf
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http://molecular-cancer.biomedcentral.com/articles/10.1186/s
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http://dx.doi.org/10.1186/s12943-015-0310-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4392793PMC
February 2015

Ligation of TLR7 on CD19(+) CD1d(hi) B cells suppresses allergic lung inflammation via regulatory T cells.

Eur J Immunol 2015 Jun 14;45(6):1842-54. Epub 2015 Apr 14.

Trinity Biomedical Sciences Institute, School of Medicine, Trinity College Dublin, Dublin, Ireland.

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http://dx.doi.org/10.1002/eji.201445211DOI Listing
June 2015

PD-L1hi B cells are critical regulators of humoral immunity.

Nat Commun 2015 Jan 22;6:5997. Epub 2015 Jan 22.

1] Translational Immunology Group, School of Medicine, Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin 2, Ireland [2] National Children's Research Centre, Our Lady's Children's Hospital, Dublin 12, Ireland [3] Institute of Molecular Medicine, School of Medicine St James's Hospital, Trinity College Dublin, Dublin 2, Ireland.

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http://dx.doi.org/10.1038/ncomms6997DOI Listing
January 2015

Cutting edge: IL-25 elicits innate lymphoid type 2 and type II NKT cells that regulate obesity in mice.

J Immunol 2013 Dec 28;191(11):5349-53. Epub 2013 Oct 28.

Trinity Biomedical Sciences Institute, School of Medicine, Trinity College Dublin, Dublin 2, Ireland;

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http://dx.doi.org/10.4049/jimmunol.1301176DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3847854PMC
December 2013

Regulation of IL-1β-induced NF-κB by hydroxylases links key hypoxic and inflammatory signaling pathways.

Proc Natl Acad Sci U S A 2013 Nov 21;110(46):18490-5. Epub 2013 Oct 21.

Systems Biology Ireland, School of Medicine and Medical Science, and Conway Institute, University College Dublin, Belfield, Dublin 4, Ireland.

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http://dx.doi.org/10.1073/pnas.1309718110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3832034PMC
November 2013

The schistosoma granuloma: friend or foe?

Front Immunol 2013 15;4:89. Epub 2013 Apr 15.

Trinity Biomedical Sciences Institute, School of Medicine, Trinity College Dublin Dublin, Ireland ; National Children's Research Centre, Our Lady's Children's Hospital Dublin, Ireland.

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http://dx.doi.org/10.3389/fimmu.2013.00089DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3625856PMC
April 2013

Suppressors of cytokine signaling 2 and 3 diametrically control macrophage polarization.

Immunity 2013 Jan 21;38(1):66-78. Epub 2012 Nov 21.

Centre for Infection and Immunity, School of Medicine Dentistry and Biomedical Sciences, Queen's University, 97 Lisburn Road, Belfast BT9 7BL, UK.

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https://linkinghub.elsevier.com/retrieve/pii/S10747613120047
Publisher Site
http://dx.doi.org/10.1016/j.immuni.2012.09.013DOI Listing
January 2013

Orphan receptor IL-17RD tunes IL-17A signalling and is required for neutrophilia.

Nat Commun 2012 ;3:1119

Department of Biology, Institute of Immunology, National University of Ireland Maynooth, Maynooth, Ireland.

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http://dx.doi.org/10.1038/ncomms2127DOI Listing
February 2013

Cutting edge: suppression of GM-CSF expression in murine and human T cells by IL-27.

J Immunol 2012 Sep 25;189(5):2079-83. Epub 2012 Jul 25.

Centre for Infection and Immunity, Queen's University Belfast, Belfast BT9 7AE, Northern Ireland.

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http://dx.doi.org/10.4049/jimmunol.1200131DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3424384PMC
September 2012

Innate type 2 cells and asthma.

Curr Opin Pharmacol 2012 Aug 29;12(4):503-9. Epub 2012 Jun 29.

Institute of Molecular Medicine, Trinity College Dublin, Ireland.

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http://dx.doi.org/10.1016/j.coph.2012.06.001DOI Listing
August 2012

Blockade of B7-H1 (programmed death ligand 1) enhances humoral immunity by positively regulating the generation of T follicular helper cells.

J Immunol 2011 May 13;186(10):5648-55. Epub 2011 Apr 13.

Institute of Molecular Medicine, St. James's Hospital, Trinity College Dublin, Dublin 8, Ireland.

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http://www.jimmunol.org/cgi/doi/10.4049/jimmunol.1003161
Publisher Site
http://dx.doi.org/10.4049/jimmunol.1003161DOI Listing
May 2011