Publications by authors named "Emilio Clementi"

100Publications

Changes in Anthropometric Parameters After Anti-TNFα Therapy in Inflammatory Bowel Disease: A Systematic Review and Meta-analysis.

BioDrugs 2020 Oct;34(5):649-668

Unit of Clinical Pharmacology, Department of Biomedical and Clinical Sciences L. Sacco, "Luigi Sacco" University Hospital, Università di Milano, 20157, Milan, Italy.

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http://dx.doi.org/10.1007/s40259-020-00444-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7519901PMC
October 2020

Defects of full-length dystrophin trigger retinal neuron damage and synapse alterations by disrupting functional autophagy.

Cell Mol Life Sci 2020 Aug 4. Epub 2020 Aug 4.

Department for Innovation in Biological, Agro-Food and Forest Systems (DIBAF), Università degli Studi della Tuscia, largo dell'Università snc, 01100, Viterbo, Italy.

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http://dx.doi.org/10.1007/s00018-020-03598-5DOI Listing
August 2020

DNA extraction from fresh and frozen plasma: an alternative for real-time PCR genotyping in pharmacogenetics.

Mol Biol Rep 2020 Aug 23;47(8):6451-6455. Epub 2020 Jul 23.

Unit of Clinical Pharmacology, Department of Laboratory Medicine, ASST Fatebenefratelli-Sacco, Milan, Italy.

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http://dx.doi.org/10.1007/s11033-020-05664-4DOI Listing
August 2020

Endoplasmic reticulum as a potential therapeutic target for covid-19 infection management?

Eur J Pharmacol 2020 Sep 17;882:173288. Epub 2020 Jun 17.

Department of Human Anatomy and Cell Science, Rady Faculty of Health Sciences, Max Rady College of Medicine, University of Manitoba, Winnipeg, Canada; Research Institute in Oncology and Hematology, CancerCare Manitoba, University of Manitoba, Winnipeg, MB, Canada; Faculty of Medicine, Katowice School of Technology, Katowice, Poland. Electronic address:

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http://dx.doi.org/10.1016/j.ejphar.2020.173288DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7297682PMC
September 2020

Does lopinavir really inhibit SARS-CoV-2?

Pharmacol Res 2020 08 11;158:104898. Epub 2020 May 11.

IRCCS E. Nedea Scientific Institute, Bosisio Parini, Italy.

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http://dx.doi.org/10.1016/j.phrs.2020.104898DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7211645PMC
August 2020

Lopinavir/ritonavir in COVID-19 patients: maybe yes, but at what dose?

J Antimicrob Chemother 2020 09;75(9):2704-2706

3rd Division of Infectious Diseases, ASST Fatebenefratelli Sacco University Hospital, Milan, Italy.

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http://dx.doi.org/10.1093/jac/dkaa190DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7239103PMC
September 2020

Therapeutic drug monitoring and pharmacogenetics of antipsychotics and antidepressants in real life settings: A 5-year single centre experience.

World J Biol Psychiatry 2020 May 6:1-12. Epub 2020 May 6.

Clinical Pharmacology Unit, Consiglio Nazionale delle Ricerche Institute of Neuroscience, Department of Biomedical and Clinical Sciences L, Sacco University Hospital, Università degli Studi di Milano, Milan, Italy.

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http://dx.doi.org/10.1080/15622975.2020.1747112DOI Listing
May 2020

Levetiracetam Improves Upper Limb Spasticity in a Patient With Unresponsive Wakefulness Syndrome: A Case Report.

Front Neurosci 2020 6;14:70. Epub 2020 Feb 6.

Neurorehabilitation and Spinal Unit, Institute of Pavia, Istituti Clinici Scientifici Maugeri IRCCS, Pavia, Italy.

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http://dx.doi.org/10.3389/fnins.2020.00070DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7015971PMC
February 2020

Are dizziness-related symptoms signals for suboptimal treatment of hypothyroidism? New insights from the FDA adverse event reporting system (FAERS) database.

Eur J Clin Pharmacol 2020 May 23;76(5):733-734. Epub 2020 Jan 23.

Unit of Clinical Pharmacology Department of Biomedical and Clinical Sciences L. Sacco, "Luigi Sacco" University Hospital, Università di Milano, 20157, Milan, Italy.

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http://dx.doi.org/10.1007/s00228-020-02836-wDOI Listing
May 2020

Efficacy of Tumour Necrosis Factor-alpha therapy in paediatric Crohn's disease patients with perianal lesions: a systematic review.

Expert Opin Biol Ther 2020 Mar 23;20(3):239-251. Epub 2020 Jan 23.

Department of General Surgery, Department of Biomedical and Clinical Sciences "Luigi Sacco", "Luigi Sacco" University Hospital, Università Degli Studi Di Milano, Milan, Italy.

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http://dx.doi.org/10.1080/14712598.2020.1718096DOI Listing
March 2020

Bullous pemphigoid induced by dipeptidyl peptidase-4 (DPP-4) inhibitors: a pharmacovigilance-pharmacodynamic/pharmacokinetic assessment through an analysis of the vigibase®.

Expert Opin Drug Saf 2019 Nov 26;18(11):1099-1108. Epub 2019 Sep 26.

Unit of Clinical Pharmacology Department of Biomedical and Clinical Sciences L. Sacco, "Luigi Sacco" University Hospital, Università di Milano , Milan , Italy.

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http://dx.doi.org/10.1080/14740338.2019.1668373DOI Listing
November 2019

Impact of Therapeutic Drug Monitoring of Antiretroviral Drugs in Routine Clinical Management of People Living With HIV: A Narrative Review.

Ther Drug Monit 2020 02;42(1):64-74

Gestione Ambulatoriale Politerapie (GAP) Outpatient Clinic, ASST Fatebenefratelli Sacco University Hospital.

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http://dx.doi.org/10.1097/FTD.0000000000000684DOI Listing
February 2020

Postpartum Bleeding in Pregnant Women Receiving SSRIs/SNRIs: New Insights From a Descriptive Observational Study and an Analysis of Data from the FAERS Database.

Clin Ther 2019 09 29;41(9):1755-1766. Epub 2019 Jul 29.

Department of Biomedical and Clinical Sciences "Luigi Sacco", Università degli Studi di Milano, Milan, Italy; Psychiatry Unit 2, ASST Fatebenefratelli Sacco, Milan, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.clinthera.2019.06.008DOI Listing
September 2019

Adverse Drug Reactions Related to Mood and Emotion in Pediatric Patients Treated for Attention Deficit/Hyperactivity Disorder: A Comparative Analysis of the US Food and Drug Administration Adverse Event Reporting System Database.

J Clin Psychopharmacol 2019 Jul/Aug;39(4):386-392

Unit of Clinical Pharmacology, Department of Biomedical and Clinical Sciences L. Sacco, "Luigi Sacco" University Hospital, Università di Milano, Milan, Italy.

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http://dx.doi.org/10.1097/JCP.0000000000001058DOI Listing
February 2020

Interaction between paracetamol and lamotrigine: new insights from the FDA Adverse Event Reporting System (FAERS) database.

Eur J Clin Pharmacol 2019 Sep 14;75(9):1323-1325. Epub 2019 Jun 14.

Unit Clinical Pharmacology, Department of Biomedical and Clinical Sciences, University Hospital "Luigi Sacco"-University of Milan ASST Fatebenefratelli-Sacco, Via G. B. Grassi, 74, 20157, Milan, Italy.

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http://dx.doi.org/10.1007/s00228-019-02691-4DOI Listing
September 2019

The β-cell effect of verapamil-based treatment in patients with type 2 diabetes: a systematic review.

Acta Diabetol 2020 Feb 6;57(2):117-131. Epub 2019 Jun 6.

Unit Clinical Pharmacology, Department of Biomedical and Clinical Sciences L. Sacco, "Luigi Sacco" University Hospital, Università di Milano, Via GB Grassi 74, 20157, Milan, Italy.

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http://dx.doi.org/10.1007/s00592-019-01370-1DOI Listing
February 2020

The Fine Tuning of Drp1-Dependent Mitochondrial Remodeling and Autophagy Controls Neuronal Differentiation.

Front Cell Neurosci 2019 4;13:120. Epub 2019 Apr 4.

Unit of Clinical Pharmacology, "Luigi Sacco" University Hospital, ASST Fatebenefratelli Sacco, Milan, Italy.

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http://dx.doi.org/10.3389/fncel.2019.00120DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6458285PMC
April 2019

Association of Hyponatraemia and Antidepressant Drugs: A Pharmacovigilance-Pharmacodynamic Assessment Through an Analysis of the US Food and Drug Administration Adverse Event Reporting System (FAERS) Database.

CNS Drugs 2019 06;33(6):581-592

Pharmacovigilance Service, Unit of Clinical Pharmacology, Department of Biomedical and Clinical Sciences L. Sacco, "Luigi Sacco" University Hospital, University of Milan ASST Fatebenefratelli-Sacco, Via G. B. Grassi, 74, 20157, Milan, Italy.

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http://dx.doi.org/10.1007/s40263-019-00631-5DOI Listing
June 2019

The impact of a successful treatment of HCV on glyco-metabolic control in diabetic patients.

Antivir Ther 2019 ;24(2):147-149

Unit of Clinical Pharmacology, Department of Biomedical and Clinical Sciences L. Sacco, 'Luigi Sacco' University Hospital, Università di Milano, Milan, Italy.

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http://dx.doi.org/10.3851/IMP3300DOI Listing
December 2019

ABCB1 c.3435C>T polymorphism is associated with platinum toxicity: a preliminary study.

Cancer Chemother Pharmacol 2019 04 22;83(4):803-808. Epub 2019 Feb 22.

Department of Oncology, ASST Fatebenefratelli-Sacco, Via Giovanni Battista Grassi, 74 20157, Milan, Italy.

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http://dx.doi.org/10.1007/s00280-019-03794-6DOI Listing
April 2019

Different effects of glucocorticoids on darunavir plasma concentrations.

Eur J Clin Pharmacol 2019 May 9;75(5):733-735. Epub 2019 Jan 9.

Gestione Ambulatoriale Politerapie (GAP) outpatient clinic, ASST Fatebenefratelli Sacco University Hospital, Milan, Italy.

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http://dx.doi.org/10.1007/s00228-019-02626-zDOI Listing
May 2019

The impact of a successful treatment of hepatitis C virus on glyco-metabolic control in diabetic patients: a systematic review and meta-analysis.

Acta Diabetol 2019 Mar 26;56(3):341-354. Epub 2018 Nov 26.

International Center for T1D, Pediatric Clinical Research Center Fondazione Romeo ed Enrica Invernizzi, Department of Biomedical and Clinical Science L. Sacco, Università di Milano, 20157, Milan, Italy.

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http://link.springer.com/10.1007/s00592-018-1257-1
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http://dx.doi.org/10.1007/s00592-018-1257-1DOI Listing
March 2019

On the Policy of the Italian Government in the Discovery, Development, and Access to Medicines.

Clin Ther 2018 11 27;40(11):1931-1940. Epub 2018 Oct 27.

Department of Experimental Medicine - Section of Pharmacology "L. Donatelli", University of Campania "Luigi Vanvitelli", Napoli, Italy.

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http://dx.doi.org/10.1016/j.clinthera.2018.09.015DOI Listing
November 2018

Weight-Change Trajectories of Pediatric Outpatients Treated with Risperidone or Aripiprazole in a Naturalistic Setting.

J Child Adolesc Psychopharmacol 2019 03 16;29(2):133-140. Epub 2018 Nov 16.

4 Unit of Clinical Pharmacology, Department of Biomedical and Clinical Sciences L. Sacco, "Luigi Sacco" University Hospital, Università di Milano , Milan, Italy .

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http://dx.doi.org/10.1089/cap.2018.0092DOI Listing
March 2019

A characterization and disproportionality analysis of medication error related adverse events reported to the FAERS database.

Expert Opin Drug Saf 2018 Dec 27;17(12):1161-1169. Epub 2018 Nov 27.

a Unit of Clinical Pharmacology, Department of Biomedical and Clinical Sciences L. Sacco , "Luigi Sacco" University Hospital, Università di Milano , Milan , Italy.

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https://www.tandfonline.com/doi/full/10.1080/14740338.2018.1
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http://dx.doi.org/10.1080/14740338.2018.1550069DOI Listing
December 2018

An unexpectedly prolonged severe hyperbilirubinemia in a patient with pre-existing hepatitis A: a role of genetic predisposition?

Clin Chem Lab Med 2019 06;57(7):e145-e148

Dipartimento di Scienze Biomediche e Cliniche 'Luigi Sacco', Università degli Studi, Milan, Italy.

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http://www.degruyter.com/view/j/cclm.ahead-of-print/cclm-201
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http://dx.doi.org/10.1515/cclm-2018-0962DOI Listing
June 2019

Interactions Between Antiepileptic and Antibiotic Drugs: A Systematic Review and Meta-Analysis with Dosing Implications.

Clin Pharmacokinet 2019 07;58(7):875-886

Unit of Clinical Pharmacology, Department of Biomedical and Clinical Sciences L. Sacco, "Luigi Sacco" University Hospital, Università di Milano, Via GB Grassi 74, 20157, Milan, Italy.

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http://dx.doi.org/10.1007/s40262-018-0720-zDOI Listing
July 2019

Central nervous system-active drug abused and overdose in children: a worldwide exploratory study using the WHO pharmacovigilance database.

Eur J Pediatr 2019 Feb 29;178(2):161-172. Epub 2018 Oct 29.

Unit of Clinical Pharmacology Department of Biomedical and Clinical Sciences L. Sacco, "Luigi Sacco" University Hospital, Università di Milano, 20157, Milan, Italy.

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http://link.springer.com/10.1007/s00431-018-3281-0
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http://dx.doi.org/10.1007/s00431-018-3281-0DOI Listing
February 2019

Real World Data on the Utilization Pattern and Safety Profile of Infliximab Originator Versus Biosimilars in Italy: A Multiregional Study.

BioDrugs 2018 Dec;32(6):607-617

Campania Pharmacovigilance and Pharmacoepidemiology Regional Centre, Section of Pharmacology "L. Donatelli", Department of Experimental Medicine, University of Campania "L. Vanvitelli", Naples, Italy.

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http://link.springer.com/10.1007/s40259-018-0313-2
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http://dx.doi.org/10.1007/s40259-018-0313-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6290713PMC
December 2018

Intraindividual and Interindividual Variability of Olanzapine Trough Concentrations in Patients Treated With the Long-Acting Injectable Formulation.

J Clin Psychopharmacol 2018 Aug;38(4):365-369

Department of Psychiatry, University of Milan, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico.

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http://dx.doi.org/10.1097/JCP.0000000000000913DOI Listing
August 2018

Clinical and genetic determinants of nevirapine plasma trough concentration.

SAGE Open Med 2018 5;6:2050312118780861. Epub 2018 Jun 5.

Infectious Diseases Unit, Department of Biomedical and Clinical Sciences "Luigi Sacco," University of Milan, Milan, Italy.

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http://dx.doi.org/10.1177/2050312118780861DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5992792PMC
June 2018

Italian Immunization Goals: A Political or Scientific Heated Debate?

Front Pharmacol 2018 30;9:574. Epub 2018 May 30.

Department of Experimental Medicine - Section of Pharmacology "L. Donatelli", University of Campania "Luigi Vanvitelli", Naples, Italy.

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http://dx.doi.org/10.3389/fphar.2018.00574DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5989663PMC
May 2018

Adverse drug events related to mood and emotion in paediatric patients treated for ADHD: A meta-analysis.

J Affect Disord 2018 10 22;238:161-178. Epub 2018 May 22.

Scientific Institute IRCCS Eugenio Medea, 23842 Bosisio Parini, Lecco, Italy.

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http://dx.doi.org/10.1016/j.jad.2018.05.021DOI Listing
October 2018

Development and Validation of a Chromatographic Ultraviolet Method for the Quantification of Isavuconazole in Human Plasma Samples.

Ther Drug Monit 2018 08;40(4):512-514

Unit of Clinical Pharmacology, L. Sacco University Hospital, Milan, Italy.

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http://dx.doi.org/10.1097/FTD.0000000000000523DOI Listing
August 2018

Selective serotonin reuptake inhibitors' passage into human milk of lactating women.

J Matern Fetal Neonatal Med 2019 Sep 6;32(18):3020-3025. Epub 2018 May 6.

a Department of Pediatrics , ASST FBF-Sacco, L. Sacco University Hospital , Milan , Italy.

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http://dx.doi.org/10.1080/14767058.2018.1455180DOI Listing
September 2019

Metformin: Prevention of genomic instability and cancer: A review.

Mutat Res Genet Toxicol Environ Mutagen 2018 Mar 31;827:1-8. Epub 2018 Jan 31.

Department of Medical Physics and Biomedical Engineering, Faculty of Medicine, Tehran University of Medical Sciences, Tehran, Iran.

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http://dx.doi.org/10.1016/j.mrgentox.2018.01.007DOI Listing
March 2018

Potential associations between atazanavir exposure and clinical outcome: a pharmacokinetic sub-study from the MODAt randomized trial.

New Microbiol 2018 Apr 2;41(2):106-111. Epub 2018 Mar 2.

Department of Infectious Diseases, San Raffaele Scientific Institute, Milan, Italy.

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April 2018

No signal of interactions between influenza vaccines and drugs used for chronic diseases: a case-by-case analysis of the vaccine adverse event reporting system and vigibase.

Expert Rev Vaccines 2018 04 9;17(4):363-381. Epub 2018 Mar 9.

a Unit of Clinical Pharmacology Department of Biomedical and Clinical Sciences L. Sacco , 'Luigi Sacco' University Hospital, Università di Milano , Milan , Italy.

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https://www.tandfonline.com/doi/full/10.1080/14760584.2018.1
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http://dx.doi.org/10.1080/14760584.2018.1442718DOI Listing
April 2018

Can We Rely on AGNP Therapeutic Targets Also For LAI Antipsychotics?

Pharmacopsychiatry 2018 Nov 27;51(6):270-271. Epub 2017 Nov 27.

Unit of Clinical Pharmacology, ASST Fatebenefratelli Sacco University Hospital, Milan, Italy.

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http://dx.doi.org/10.1055/s-0043-122603DOI Listing
November 2018

Performance of a tracheostomy removal protocol for pediatric patients in rehabilitation after acquired brain injury: Factors associated with timing and possibility of decannulation.

Pediatr Pulmonol 2017 Nov 26;52(11):1509-1517. Epub 2017 Sep 26.

Scientific Institute IRCCS Eugenio Medea, Bosisio Parini, Lecco, Italy.

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http://dx.doi.org/10.1002/ppul.23832DOI Listing
November 2017

Levetiracetam-induced rhabdomyolysis: Analysis of reports from the Food and Drug Administration's Adverse Event Reporting System database.

Muscle Nerve 2017 12 30;56(6):E176-E178. Epub 2017 Sep 30.

Department of Biomedical and Clinical Sciences, Clinical Pharmacology Unit, ASST Fatebenefratelli-Sacco University Hospital, University of Milan, Milan, Italy.

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http://dx.doi.org/10.1002/mus.25972DOI Listing
December 2017

On the association between human papillomavirus vaccine and sleep disorders: Evaluation based on vaccine adverse events reporting systems.

J Neurol Sci 2017 09 4;380:275-276. Epub 2017 Aug 4.

Scientific Institute, IRCCS E. Medea, Bosisio Parini, Lecco, Italy; Unit of Clinical Pharmacology, Department of Biomedical and Clinical Sciences, Consiglio Nazionale delle Ricerche Institute of Neuroscience, L. Sacco University Hospital, Università di Milano, Milan, Italy.

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http://dx.doi.org/10.1016/j.jns.2017.07.051DOI Listing
September 2017

Application of Quality by Design Approach to Bioanalysis: Development of a Method for Elvitegravir Quantification in Human Plasma.

Ther Drug Monit 2017 10;39(5):531-542

*Unit of Clinical Pharmacology, L. Sacco University Hospital, Milano, Italy; †Department of Drug Sciences, University of Pavia, Pavia, Italy; ‡Clinical Pharmacology Unit, CNR Institute of Neuroscience, Department of Biomedical and Clinical Sciences, L. Sacco University Hospital, Università di Milano, Milano, Italy; §Scientific Institute IRCCS Eugenio Medea, Bosisio Parini, Italy; and ¶Department of Pharmaceutical Sciences, Università degli Studi di Milano, Milan, Italy.

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http://dx.doi.org/10.1097/FTD.0000000000000428DOI Listing
October 2017

Effect of N-Desalkylquetiapine/Quetiapine Plasma Level Ratio on Anxiety and Depression in Bipolar Disorder: A Prospective Observational Study.

Ther Drug Monit 2017 08;39(4):441-445

*Department of Neuroscience and Mental Health, Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico, Milano, Italy; †Unit of Clinical Pharmacology, ASST Fatebenefratelli Sacco University Hospital, Milano, Italy; ‡Department of Biomedical and Clinical Sciences, Consiglio Nazionale delle Ricerche Institute of Neuroscience, University Hospital, Luigi Sacco, Università di Milano, Milan, Italy; and §Scientific Institute IRCCS E. Medea, Bosisio Parini (LC), Italy.

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http://dx.doi.org/10.1097/FTD.0000000000000413DOI Listing
August 2017

Auditory and visual hallucinations after influenza vaccine: a case report.

Ther Adv Vaccines 2017 Feb 21;5(1):25-27. Epub 2016 Oct 21.

Unit of Clinical Pharmacology, Department of Biomedical and Clinical Sciences, ASST Fatebenefratelli-Sacco, Luigi Sacco University Hospital, Università di Milano, Milan, Italy.

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http://dx.doi.org/10.1177/2051013616673554DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5349333PMC
February 2017

Effects of ritonavir and cobicistat on dolutegravir exposure: when the booster can make the difference.

J Antimicrob Chemother 2017 06;72(6):1842-1844

Unit of Clinical Pharmacology, L. Sacco University Hospital, Milan, Italy.

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http://dx.doi.org/10.1093/jac/dkx055DOI Listing
June 2017

On the association between human papillomavirus vaccine and sleep disorders: Evaluation based on vaccine adverse events reporting systems.

J Neurol Sci 2017 Feb 29;373:179-181. Epub 2016 Dec 29.

Scientific Institute, IRCCS E. Medea, Bosisio Parini, Lecco, Italy; Unit of Clinical Pharmacology, Department of Biomedical and Clinical Sciences, Consiglio Nazionale delle Ricerche Institute of Neuroscience, University Hospital "Luigi Sacco", Milan, Italy.

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http://dx.doi.org/10.1016/j.jns.2016.12.067DOI Listing
February 2017

How Relevant is the Interaction Between Dolutegravir and Metformin in Real Life?

J Acquir Immune Defic Syndr 2017 05;75(1):e24-e26

*Department of Infectious Diseases, L. Sacco University Hospital, Milan, Italy †Clinical Pharmacology Unit, Consiglio Nazionale delle Ricerche Institute of Neuroscience, Department of Biomedical and Clinical Sciences, L. Sacco University Hospital, Università degli Studi di Milano, Milan, Italy ‡E. Medea Scientific Institute, Bosisio Parini, Italy §School of Clinical Medicine, University of the Witwatersrand, Johannesburg, South Africa ‖Unit of Clinical Pharmacology, L. Sacco University Hospital, Milan, Italy.

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http://dx.doi.org/10.1097/QAI.0000000000001292DOI Listing
May 2017

HLA-B*57.

Pharmacogenet Genomics 2017 02;27(2):81-82

aClinical Pharmacology Unit, Department of Laboratory Medicine, 'Luigi Sacco' University Hospital, ASST Fatebenefratelli-Sacco bUnit of Clinical Pharmacology, Department of Biomedical and Clinical Sciences, Institute of Neuroscience, Consiglio Nazionale delle Ricerche, 'Luigi Sacco' University Hospital, Milan cScientific Institute, IRCCS E. Medea, Lecco, Italy.

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http://dx.doi.org/10.1097/FPC.0000000000000258DOI Listing
February 2017

Pharmacokinetics and Pharmacogenetics of Selective Serotonin Reuptake Inhibitors During Pregnancy: An Observational Study.

Ther Drug Monit 2017 04;39(2):197-201

*Department of Pediatrics, ASST Fatebenefratelli-Sacco, L. Sacco University Hospital, Milan; †Unit of Clinical Pharmacology, ASST Fatebenefratelli-Sacco, L. Sacco University Hospital, Milan; ‡Department of Gynecology and Obstetrics, ASST Fatebenefratelli-Sacco, L. Sacco Hospital, University Hospital, Milan; §Department of Pediatrics, ASST Fatebenefratelli-Sacco, Ospedale dei Bambini V. Buzzi, Milan; ¶Clinical Pharmacology Unit, Consiglio Nazionale delle Ricerche Institute of Neuroscience, Department of Biomedical and Clinical Sciences, L. Sacco University Hospital, Università degli Studi di Milano, Milan; and ‖E. Medea Scientific Institute, Bosisio Parini, Italy.

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http://Insights.ovid.com/crossref?an=00007691-201704000-0001
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http://dx.doi.org/10.1097/FTD.0000000000000370DOI Listing
April 2017

Dolutegravir plasma concentrations according to companion antiretroviral drug: unwanted drug interaction or desirable boosting effect?

Antivir Ther 2017 23;22(4):353-356. Epub 2016 Dec 23.

Department of Infectious Diseases, L. Sacco University Hospital, Milan, Italy.

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http://dx.doi.org/10.3851/IMP3119DOI Listing
May 2018

Reversal of Defective Mitochondrial Biogenesis in Limb-Girdle Muscular Dystrophy 2D by Independent Modulation of Histone and PGC-1α Acetylation.

Cell Rep 2016 12;17(11):3010-3023

Department of Biomedical and Clinical Sciences, Unit of Clinical Pharmacology, University Hospital "Luigi Sacco"-ASST Fatebenefratelli Sacco, National Research Council-Institute of Neuroscience, Università degli Studi di Milano, 20157 Milano, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2016.11.044DOI Listing
December 2016

Advanced technologies charting a new path for traditional Chinese medicine drug discovery.

Pharmacol Res 2017 Mar 10;117:65-66. Epub 2016 Dec 10.

Department of Pharmacology, Yong Loo Lin School of Medicine, National University of Singapore, 117600, Singapore.

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http://dx.doi.org/10.1016/j.phrs.2016.12.010DOI Listing
March 2017

Development of an HPLC-UV assay method for the simultaneous quantification of nine antiretroviral agents in the plasma of HIV-infected patients.

J Pharm Anal 2016 Dec 14;6(6):396-403. Epub 2016 Jun 14.

Clinical Pharmacology Unit, CNR Institute of Neuroscience, Department of Biomedical and Clinical Sciences, L. Sacco University Hospital, Università di Milano, 20157 Milan, Italy.

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http://dx.doi.org/10.1016/j.jpha.2016.05.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5762929PMC
December 2016

A retrospective review of paediatric adverse drug reactions reported in Lombardy and Croatia from 2005 to 2013.

Expert Opin Drug Saf 2016 Dec;15(sup2):35-43

a Unit of Clinical Pharmacology, Department of Biomedical and Clinical Sciences , University Hospital 'Luigi Sacco', Università di Milano , Milan , Italy.

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http://dx.doi.org/10.1080/14740338.2016.1253678DOI Listing
December 2016

Second generation antipsychotics in 'real-life' paediatric patients. Adverse drug reactions and clinical outcomes of drug switch.

Expert Opin Drug Saf 2016 Dec;15(sup2):1-8

a Campania Regional Centre for Pharmacovigilance and Pharmacoepidemiology, Department of Experimental Medicine, Section of Pharmacology L. Donatelli, School of Medicine and Surgery , Second University of Naples , Naples , Italy.

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http://dx.doi.org/10.1080/14740338.2016.1229301DOI Listing
December 2016

Identification of Different Patterns of Dabigatran In Vivo Bioactivation in Patients on Maintenance Anticoagulation Therapy.

Ther Drug Monit 2016 12;38(6):814-816

*Unit of Clinical Pharmacology, L. Sacco University Hospital, Milano, Italy†Department of Pharmaceutical Sciences, Università degli Studi di Milano, Milano, Italy‡Department of Internal Medicine and Medical Specialities, Sapienza University of Rome, Roma, Italy§Clinical Pharmacology Unit, CNR Institute of Neuroscience, Department of Biomedical and Clinical Sciences, L. Sacco University Hospital, Università di Milano, Milano, Italy¶Scientific Institute IRCCS Eugenio Medea, Bosisio Parini, Italy.

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http://dx.doi.org/10.1097/FTD.0000000000000342DOI Listing
December 2016

Precipitation of Carbamazepine-Controlled Seizures Due to Low-Dose Risperidone in a Child: A Conspiracy to Unbalance Blood Electrolytes.

J Clin Psychopharmacol 2016 Dec;36(6):729-730

Scientific Institute IRCCS Eugenio Medea Bosisio Parini, Lecco, Italy Associazione La Nostra Famiglia Presidio di Riabilitazione di Treviso Treviso, Italy Epilepsy and Clinical Neurophysiology Unit Scientific Institute IRCCS Eugenio Medea Conegliano, Treviso, Italy Scientific Institute IRCCS Eugenio Medea Bosisio Parini, Lecco, Italy Scientific Institute IRCCS Eugenio Medea Bosisio Parini, Lecco, Italy and Unit of Clinical Pharmacology CNR Institute of Neuroscience Department of Biomedical and Clinical Sciences L. Sacco "Luigi Sacco" University Hospital Università di Milano, Milan, Italy

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http://dx.doi.org/10.1097/JCP.0000000000000593DOI Listing
December 2016

The combination of pharmacogenetic and pharmacokinetic analyses to optimize clomipramine dosing in major depression: a case report.

J Clin Pharm Ther 2017 Feb 31;42(1):119-121. Epub 2016 Oct 31.

Department of Psychiatry, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, University of Milan, Milan, Italy.

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http://dx.doi.org/10.1111/jcpt.12478DOI Listing
February 2017

Therapeutic drug management of linezolid: a missed opportunity for clinicians?

Int J Antimicrob Agents 2016 Dec 12;48(6):728-731. Epub 2016 Oct 12.

Clinical Pharmacology Unit, Consiglio Nazionale delle Ricerche Institute of Neuroscience, Department of Biomedical and Clinical Sciences, L. Sacco University Hospital, Università degli Studi di Milano, Milan, Italy; E. Medea Scientific Institute, Bosisio Parini, Italy.

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http://dx.doi.org/10.1016/j.ijantimicag.2016.08.023DOI Listing
December 2016

Erratum to: Severe somatoform and dysautonomic syndromes after HPV vaccination: case series and review of literature.

Immunol Res 2017 02;65(1):117-119

Unit of Clinical Pharmacology, Department of Biomedical and Clinical Sciences, National Research Council-Institute of Neuroscience, University Hospital L. Sacco, University of Milano, Milan, Italy.

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http://dx.doi.org/10.1007/s12026-016-8865-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6828184PMC
February 2017

Paroxysmal Sympathetic Hyperactivity in Pediatric Rehabilitation: Pathological Features and Scheduled Pharmacological Therapies.

J Head Trauma Rehabil 2017 Mar/Apr;32(2):117-124

Scientific Institute IRCCS Eugenio Medea, Lecco, Italy (Drs Pozzi, Locatelli, Galbiati, Clementi, and Strazzer); Regional Centre for Pharmacovigilance of Lombardy, Milan, Italy (Dr Conti); Unit of Clinical Pharmacology, Department of Biomedical and Clinical Sciences L. Sacco, "Luigi Sacco" University Hospital, Università di Milano, Milan, Italy (Dr Radice); and Unit of Clinical Pharmacology, CNR Institute of Neuroscience, Department of Biomedical and Clinical Sciences L. Sacco, "Luigi Sacco" University Hospital, Università di Milano, Milan, Italy (Dr Clementi).

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http://dx.doi.org/10.1097/HTR.0000000000000255DOI Listing
February 2018

When food can make the difference: The case of elvitegravir-based co-formulation.

Int J Pharm 2016 Oct 31;512(1):301-304. Epub 2016 Aug 31.

Department of Infectious Diseases, L. Sacco University Hospital, Milan, Italy.

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http://dx.doi.org/10.1016/j.ijpharm.2016.08.063DOI Listing
October 2016

Severe somatoform and dysautonomic syndromes after HPV vaccination: case series and review of literature.

Immunol Res 2017 02;65(1):106-116

Unit of Clinical Pharmacology, Department of Biomedical and Clinical Sciences, National Research Council-Institute of Neuroscience, University Hospital L. Sacco, University of Milano, Milan, Italy.

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http://dx.doi.org/10.1007/s12026-016-8820-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5406435PMC
February 2017

Breast Hypertrophy Induced by Ombitasvir/Paritaprevir/Ritonavir and Ribavirina.

Breast J 2016 Nov 4;22(6):708-709. Epub 2016 Aug 4.

Unit of Clinical Pharmacology, Department of Biomedical and Clinical Sciences, "Luigi Sacco" University Hospital, Università di Milano, Milan, Italy.

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http://dx.doi.org/10.1111/tbj.12656DOI Listing
November 2016

Determinants of bone diseases in tenofovir-treated HIV patients.

AIDS 2016 06;30(10):1686-7

aDepartment of Infectious Diseases, Luigi Sacco University Hospital, Milan, Italy bUnit of Clinical Pharmacology, Luigi Sacco University Hospital, Milan, Italy cClinical Pharmacology Unit, CNR Institute of Neuroscience, Department Biomedical and Clinical Sciences, Luigi Sacco University Hospital, Università di Milano, Milan Italy dScientific Institute IRCCS E.Medea, Bosisio Parini, Italy eSchool of Clinical Medicine, University of the Witwatersrand, Johannesburg, South Africa.

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http://dx.doi.org/10.1097/QAD.0000000000001094DOI Listing
June 2016

Is there still room for therapeutic drug monitoring of linezolid in patients with tuberculosis?

Eur Respir J 2016 Apr;47(4):1287-8

Clinical Pharmacology Unit, CNR Institute of Neuroscience, Dept Biomedical and Clinical Sciences, L. Sacco University Hospital, Università di Milano, Milan, Italy Scientific Institute IRCCS E. Medea, Bosisio Parini, Italy.

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http://dx.doi.org/10.1183/13993003.01913-2015DOI Listing
April 2016