Emilio Ciusani

Emilio Ciusani

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Emilio Ciusani

Emilio Ciusani

Publications by authors named "Emilio Ciusani"

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Hyperexcitability in Cultured Cortical Neuron Networks from the G93A-SOD1 Amyotrophic Lateral Sclerosis Model Mouse and its Molecular Correlates.

Neuroscience 2019 Sep 7;416:88-99. Epub 2019 Aug 7.

World Research Hub Initiative (WRHI), Institute of Innovative Research, Tokyo Institute of Technology, Yokohama 226-8503, Japan; Complex Systems Theory Department, Institute of Nuclear Physics, Polish Academy of Sciences (IFJ-PAN), 31-342 Kraków, Poland; Center for Mind/Brain Sciences (CIMeC), University of Trento, 38123 Trento, Italy.

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http://dx.doi.org/10.1016/j.neuroscience.2019.07.041DOI Listing
September 2019

AXL Downstream Targeting Unravels Synergistic Drug Combinations in Ovarian Carcinoma Cells.

Anticancer Res 2019 Jul;39(7):3803-3808

Molecular Pharmacology Unit, Department of Applied Research and Technological Development, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy

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http://dx.doi.org/10.21873/anticanres.13529DOI Listing
July 2019

Sulforaphane Cannot Protect Human Fibroblasts From Repeated, Short and Sublethal Treatments with Hydrogen Peroxide.

Int J Environ Res Public Health 2019 02 23;16(4). Epub 2019 Feb 23.

Center for Complexity and Biosystems, Department of Environmental Science and Policy, University of Milan, via Celoria 26, 20133 Milano, Italy.

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http://dx.doi.org/10.3390/ijerph16040657DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6406632PMC
February 2019

Long-Lasting Anti-Inflammatory Activity of Human Microfragmented Adipose Tissue.

Stem Cells Int 2019 19;2019:5901479. Epub 2019 Feb 19.

Cellular Neurobiology Laboratory, Department of Cerebrovascular Diseases, Fondazione IRCCS Neurological Institute C. Besta, Milan, Italy.

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http://dx.doi.org/10.1155/2019/5901479DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6399530PMC
February 2019

Uptake-release by MSCs of a cationic platinum(II) complex active in vitro on human malignant cancer cell lines.

Biomed Pharmacother 2018 Dec 12;108:111-118. Epub 2018 Sep 12.

CRC StaMeTec-Department of Biomedical, Surgical and Dental Sciences, University of Milan, Via Pascal 36, 20133 Milan, Italy.

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http://dx.doi.org/10.1016/j.biopha.2018.09.040DOI Listing
December 2018

An RGD small-molecule integrin antagonist induces detachment-mediated anoikis in glioma cancer stem cells.

Int J Oncol 2018 Dec 3;53(6):2683-2694. Epub 2018 Oct 3.

Department of Drug Sciences, University of Pavia, I-27100 Pavia, Italy.

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http://dx.doi.org/10.3892/ijo.2018.4583DOI Listing
December 2018

Botulinum toxin type A affects the transcriptome of cell cultures derived from muscle biopsies of controls and spastic patients.

Toxicol In Vitro 2018 Aug 6;50:124-136. Epub 2018 Mar 6.

Division of Neuromuscular Diseases and Neuroimmunology, Fondazione IRCCS Istituto Neurologico "C. Besta", Milano, Italy.

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https://linkinghub.elsevier.com/retrieve/pii/S08872333183004
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http://dx.doi.org/10.1016/j.tiv.2018.02.008DOI Listing
August 2018

Radiotherapy of meningioma: a treatment in need of radiobiological research.

Int J Radiat Biol 2018 07 19;94(7):621-627. Epub 2018 Jun 19.

a Neurosurgery Department, Radiotherapy Unit , Istituto Neurologico Fondazione C. Besta , Milan , Italy.

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http://dx.doi.org/10.1080/09553002.2018.1478157DOI Listing
July 2018

A case of unusually long survival after leptomeningeal carcinomatosis diagnosis.

J Neurooncol 2018 Mar 2;137(1):215-218. Epub 2017 Dec 2.

Neuroscience Department-Neurology/Stroke Unit, Ospedale A. Manzoni, ASST Lecco, Lecco, Italy.

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http://dx.doi.org/10.1007/s11060-017-2705-4DOI Listing
March 2018

FoxO-1 contributes to the efficacy of the combination of the XPO1 inhibitor selinexor and cisplatin in ovarian carcinoma preclinical models.

Biochem Pharmacol 2018 01 16;147:93-103. Epub 2017 Nov 16.

Molecular Pharmacology Unit, Fondazione IRCCS Istituto Nazionale dei Tumori, via Amadeo 42, 20133 Milan, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.bcp.2017.11.009DOI Listing
January 2018

Changes in Red Blood Cell membrane lipid composition: A new perspective into the pathogenesis of PKAN.

Mol Genet Metab 2017 06 18;121(2):180-189. Epub 2017 Apr 18.

Unit of Molecular Neurogenetics, Pierfranco and Luisa Mariani Centre for the Study of Mitochondrial Disorders in Children, Foundation IRCCS Neurological Institute C. Besta, Via Temolo 4, 20126 Milan, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.ymgme.2017.04.006DOI Listing
June 2017

In vitro antineoplastic effects of brivaracetam and lacosamide on human glioma cells.

J Exp Clin Cancer Res 2017 06 6;36(1):76. Epub 2017 Jun 6.

Laboratory of Clinical Pathology and Medical Genetics, Foundation IRCCS Neurological Institute C. Besta, Via Celoria, 11, 20133, Milan, Italy.

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http://dx.doi.org/10.1186/s13046-017-0546-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5460451PMC
June 2017

Establishment, characterization and long-term culture of human endocrine pancreas-derived microvascular endothelial cells.

Cytotherapy 2017 01 11;19(1):141-152. Epub 2016 Nov 11.

Cellular Neurobiology Laboratory, Department of Cerebrovascular Diseases, IRCCS Neurological Institute C. Besta, Milan, Italy.

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http://dx.doi.org/10.1016/j.jcyt.2016.10.005DOI Listing
January 2017

Intrathecal synthesis of onconeural antibodies in patients with paraneoplastic syndromes.

J Neuroimmunol 2016 Jan 22;290:119-22. Epub 2015 Nov 22.

Laboratory of Clinical Pathology and Medical Genetics, Foundation IRCCS Neurological Institute C. Besta, Via Celoria, 11, 20133 Milan, Italy.

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http://dx.doi.org/10.1016/j.jneuroim.2015.11.016DOI Listing
January 2016

Au nanoparticle-based sensor for apomorphine detection in plasma.

Beilstein J Nanotechnol 2015 26;6:2224-32. Epub 2015 Nov 26.

Dipartimento di Energia, Politecnico di Milano, Via Ponzio 34/3, 20133 Milano, Italy.

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http://dx.doi.org/10.3762/bjnano.6.228DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4685758PMC
January 2016

Overshoot during phenotypic switching of cancer cell populations.

Sci Rep 2015 Oct 23;5:15464. Epub 2015 Oct 23.

Center for Complexity and Biosystems, Department of Bioscience, University of Milano, via Celoria 26, 20133 Milano, Italy.

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http://dx.doi.org/10.1038/srep15464DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4616026PMC
October 2015

AAV-mediated liver-specific MPV17 expression restores mtDNA levels and prevents diet-induced liver failure.

Mol Ther 2014 Jan 3;22(1):10-7. Epub 2013 Jul 3.

1] Unit of Molecular Neurogenetics, The Foundation "Carlo Besta" Institute of Neurology IRCCS, Milan, Italy [2] MRC-Mitochondrial Biology Unit, Cambridge, UK.

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https://linkinghub.elsevier.com/retrieve/pii/S15250016163111
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http://dx.doi.org/10.1038/mt.2013.230DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3880585PMC
January 2014

Antitumor activity of a novel homodimeric SMAC mimetic in ovarian carcinoma.

Mol Pharm 2014 Jan 27;11(1):283-93. Epub 2013 Nov 27.

Department of Experimental Oncology and Molecular Medicine, Fondazione IRCCS Istituto Nazionale dei Tumori , Via Amadeo 42, Milan 20133, Italy.

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http://dx.doi.org/10.1021/mp4004578DOI Listing
January 2014

Circulating T regulatory cells migration and phenotype in glioblastoma patients: an in vitro study.

J Neurooncol 2013 Dec 5;115(3):353-63. Epub 2013 Sep 5.

Laboratory of Clinical Pathology and Medical Genetics, Foundation IRCCS Neurological Institute C. Besta, Via Celoria, 11, 20133, Milan, Italy.

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http://dx.doi.org/10.1007/s11060-013-1236-xDOI Listing
December 2013

Exacerbation of experimental autoimmune encephalomyelitis by passive transfer of IgG antibodies from a multiple sclerosis patient responsive to immunoadsorption.

J Neuroimmunol 2013 Sep 13;262(1-2):19-26. Epub 2013 Jun 13.

Neuroimmunology and Neuromuscular Disorders Unit, Foundation IRCCS Neurological Institute C. Besta, Via Celoria 11, 20133 Milan, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.jneuroim.2013.05.010DOI Listing
September 2013

Isolation and expansion of human and mouse brain microvascular endothelial cells.

Nat Protoc 2013 Sep 8;8(9):1680-93. Epub 2013 Aug 8.

Laboratory of Cellular Neurobiology, Istituto Di Ricovero e Cura a Carattere Scientifico Foundation Neurological Institute Carlo Besta, Milan, Italy.

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http://dx.doi.org/10.1038/nprot.2013.107DOI Listing
September 2013

Human skin-derived fibroblasts acquire in vitro anti-tumor potential after priming with Paclitaxel.

Anticancer Agents Med Chem 2013 Mar;13(3):523-30

Department of Biomedical, Surgical and Dental Sciences, University of Milan, Via Pascal 36, 20133 Milan, Italy.

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March 2013

A small-molecule RGD-integrin antagonist inhibits cell adhesion, cell migration and induces anoikis in glioblastoma cells.

Int J Oncol 2013 Jan 20;42(1):83-92. Epub 2012 Nov 20.

Department of Developmental and Molecular Biology, Albert Einstein College of Medicine of Yeshiva University, Bronx, NY 10461, USA.

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http://dx.doi.org/10.3892/ijo.2012.1708DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3583633PMC
January 2013

Expression of neural and neurotrophic markers in nucleus pulposus cells isolated from degenerated intervertebral disc.

J Orthop Res 2012 Sep 28;30(9):1470-7. Epub 2012 Feb 28.

The Cellular Neurobiology Laboratory, Cerebrovascular Diseases Unit, IRCCS Foundation Neurological Institute "C. Besta", via Celoria, 11 20133 Milan, Italy.

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http://dx.doi.org/10.1002/jor.22098DOI Listing
September 2012

Decrease in circulating endothelial progenitor cells in treated glioma patients.

J Neurooncol 2012 May 14;108(1):123-9. Epub 2012 Feb 14.

Laboratory of Clinical Pathology and Medical Genetics, Fondazione IRCCS Istituto Neurologico C. Besta, Via Celoria 11, 20133, Milano, MI, Italy.

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http://dx.doi.org/10.1007/s11060-012-0805-8DOI Listing
May 2012

Role of tyrosyl-DNA phosphodiesterase 1 and inter-players in regulation of tumor cell sensitivity to topoisomerase I inhibition.

Biochem Pharmacol 2012 Jan 29;83(1):27-36. Epub 2011 Sep 29.

Molecular Pharmacology Unit, Dept. Experimental Oncology and Molecular Medicine, Fondazione IRCCS Istituto Nazionale Tumori, Milan, Italy.

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http://dx.doi.org/10.1016/j.bcp.2011.09.021DOI Listing
January 2012

Three-dimensional self-organizing neural architectures: a neural stem cells reservoir and a system for neurodevelopmental studies.

Tissue Eng Part C Methods 2011 Nov 29;17(11):1109-20. Epub 2011 Aug 29.

Laboratory of Cellular Neurobiology, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy.

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http://dx.doi.org/10.1089/ten.TEC.2010.0622DOI Listing
November 2011

Increased migration of a human glioma cell line after in vitro CyberKnife irradiation.

Cancer Biol Ther 2011 Oct 1;12(7):629-33. Epub 2011 Oct 1.

Laboratory of Clinical Investigation, Fondazione IRCCS Istituto Neurologico C. Besta, Milano, Italy.

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http://dx.doi.org/10.4161/cbt.12.7.16862DOI Listing
October 2011

In vitro effects of Cyberknife-driven intermittent irradiation on glioblastoma cell lines.

Neurol Sci 2011 Aug 8;32(4):579-88. Epub 2011 Feb 8.

Laboratory of Clinical Investigation, Fondazione IRCCS Istituto Neurologico C. Besta, Milan, Italy.

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http://dx.doi.org/10.1007/s10072-011-0485-8DOI Listing
August 2011

PBMCs are additional sites of productive infection of bovine papillomavirus type 2.

J Gen Virol 2011 Aug 27;92(Pt 8):1787-94. Epub 2011 Apr 27.

Dipartimento di Patologia e Sanità Animale, Università di Napoli Federico II, Napoli, Italy.

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http://jgv.microbiologyresearch.org/content/journal/jgv/10.1
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http://dx.doi.org/10.1099/vir.0.031740-0DOI Listing
August 2011

A mesenchymal stromal cell line resistant to paclitaxel that spontaneously differentiates into osteoblast-like cells.

Cell Biol Toxicol 2011 Jun 29;27(3):169-80. Epub 2010 Dec 29.

Department of Public Health–Microbiology–Virology, University of Milan, Via Pascal 36, 20133, Milan, Italy.

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http://dx.doi.org/10.1007/s10565-010-9179-xDOI Listing
June 2011

Expression of the new CXCL12 receptor, CXCR7, in gliomas.

Cancer Biol Ther 2011 Jan 15;11(2):242-53. Epub 2011 Jan 15.

Neuropathology Unit, Istituto Nazionale Neurologico Carlo Besta, Milan, Italy.

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http://dx.doi.org/10.4161/cbt.11.2.13951DOI Listing
January 2011

CXCR6, a newly defined biomarker of tissue-specific stem cell asymmetric self-renewal, identifies more aggressive human melanoma cancer stem cells.

PLoS One 2010 Dec 22;5(12):e15183. Epub 2010 Dec 22.

Programs in Regenerative Biology and Cancer Biology, Adult Stem Cell Technology Center, Boston Biomedical Research Institute, Watertown, Massachusetts, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0015183PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3008677PMC
December 2010

CD45+/CD133+ positive cells expanded from umbilical cord blood expressing PDX-1 and markers of pluripotency.

Cell Biol Int 2010 Aug;34(8):783-90

Department of Public Health, Microbiology and Virology, University of Milan, Milan, Italy.

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http://dx.doi.org/10.1042/CBI20090236DOI Listing
August 2010

Human neural stem cells: a model system for the study of Lesch-Nyhan disease neurological aspects.

Hum Mol Genet 2010 May 16;19(10):1939-50. Epub 2010 Feb 16.

Laboratory of Cellular Neurobiology, UO Cerebrovascular Diseases, Fondazione IRCCS Istituto Neurologico Carlo Besta, via Celoria 11, 20133 Milan, Italy.

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http://dx.doi.org/10.1093/hmg/ddq072DOI Listing
May 2010

Homocysteine plasma levels in patients with migraine with aura.

Neurol Sci 2008 May;29 Suppl 1:S173-5

L. Mandic Hospital, Via L. Mandic 1, Merate (LC), Italy.

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http://dx.doi.org/10.1007/s10072-008-0917-2DOI Listing
May 2008

CD4+CD25+ regulatory T cells specific for a thymus-expressed antigen prevent the development of anaphylaxis to self.

J Immunol 2008 Apr;180(7):4433-40

Immunology and Muscular Pathology Unit, Neurological Institute Foundation Carlo Besta, Milan, Italy.

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http://dx.doi.org/10.4049/jimmunol.180.7.4433DOI Listing
April 2008

Valproic acid increases the in vitro effects of nitrosureas on human glioma cell lines.

Oncol Res 2007 ;16(10):453-63

Department of Clinical Investigation, Neurological National Institute Carlo Besta, Milan, Italy.

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http://dx.doi.org/10.3727/096504007783338340DOI Listing
March 2008

In vitro study of low molecular weight heparin effect on cell growth and cell invasion in primary cell cultures of high-grade gliomas.

Oncol Res 2006 ;16(5):245-50

Laboratory of Clinical Investigation, Department of Neurology, Department of Neurosurgery, National Neurological Institute "C. Besta," Via Celoria 11, 20133 Milan, Italy.

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http://dx.doi.org/10.3727/000000006783981053DOI Listing
March 2007

An effect of the PAI-1 4G/5G polymorphism on cholesterol levels may explain conflicting associations with myocardial infarction and stroke.

Cerebrovasc Dis 2006 30;22(2-3):191-5. Epub 2006 May 30.

Cerebrovascular Diseases Unit, Istituto Nazionale Neurologico Carlo Besta, Milano, Italy.

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http://dx.doi.org/10.1159/000093604DOI Listing
October 2006

Sensitization to gimatecan-induced apoptosis by tumor necrosis factor-related apoptosis inducing ligand in prostate carcinoma cells.

Biochem Pharmacol 2006 Mar 24;71(6):791-8. Epub 2006 Jan 24.

Preclinical Chemotherapy and Pharmacology Unit, Department of Experimental Oncology and Laboratories, Istituto Nazionale per lo Studio e la Cura dei Tumori, Via Venezian 1, 20133 Milan, Italy.

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http://linkinghub.elsevier.com/retrieve/pii/S000629520500849
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http://dx.doi.org/10.1016/j.bcp.2005.12.020DOI Listing
March 2006

The therapeutic potential of neural stem/progenitor cells in murine globoid cell leukodystrophy is conditioned by macrophage/microglia activation.

Neurobiol Dis 2006 Feb 30;21(2):314-23. Epub 2005 Sep 30.

Istituto Nazionale Neurologico C. Besta, Department of Experimental Neuro-Oncology and Diagnostics, via Celoria 11, 20133 Milano, Italy.

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http://dx.doi.org/10.1016/j.nbd.2005.07.016DOI Listing
February 2006

Production and post-surgical modification of VEGF, tPA and PAI-1 in patients with glioma.

Cancer Biol Ther 2006 Feb 28;5(2):204-9. Epub 2006 Feb 28.

National Neurological Institute "C. Besta", Milan, Italy.

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http://dx.doi.org/10.4161/cbt.5.2.2357DOI Listing
February 2006

Effect of association of temozolomide with other chemotherapic agents on cell growth inhibition in glioma cell lines.

Oncol Res 2004 ;14(7-8):325-30

Laboratory of Clinical Investigation, Department of Neurology, National Neurological Institute "C Besta" Via Celoria, Milan, Italy.

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http://dx.doi.org/10.3727/0965040041292341DOI Listing
January 2005