Publications by authors named "Emilio Casanova"

60Publications

Targeting Mutant Non-Small-Cell Lung Cancer: Past, Present and Future.

Int J Mol Sci 2020 Jun 17;21(12). Epub 2020 Jun 17.

Department of Physiology, Center of Physiology and Pharmacology & Comprehensive Cancer Center (CCC), Medical University of Vienna, 1090 Vienna, Austria.

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http://dx.doi.org/10.3390/ijms21124325DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7352653PMC
June 2020

STAT3: Versatile Functions in Non-Small Cell Lung Cancer.

Cancers (Basel) 2020 Apr 29;12(5). Epub 2020 Apr 29.

Department of Physiology, Center of Physiology and Pharmacology & Comprehensive Cancer Center (CCC), Medical University of Vienna, AT-1090 Vienna, Austria.

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http://dx.doi.org/10.3390/cancers12051107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7281271PMC
April 2020

[CHEK1 expression and inhibitors in TP53 mutant cancer].

Magy Onkol 2019 Dec 11;63(4):345-352. Epub 2019 Nov 11.

II. Sz. Gyermekgyógyászati Klinika, Semmelweis Egyetem, Budapest, Hungary.

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December 2019

A Mouse Model to Assess STAT3 and STAT5A/B Combined Inhibition in Health and Disease Conditions.

Cancers (Basel) 2019 Aug 22;11(9). Epub 2019 Aug 22.

Department of Physiology, Center of Physiology and Pharmacology, Comprehensive Cancer Center (CCC), Medical University of Vienna, 1090 Vienna, Austria.

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http://dx.doi.org/10.3390/cancers11091226DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6770775PMC
August 2019

JAK-STAT inhibition impairs K-RAS-driven lung adenocarcinoma progression.

Int J Cancer 2019 12 10;145(12):3376-3388. Epub 2019 Sep 10.

Department of Physiology, Center of Physiology and Pharmacology & Comprehensive Cancer Center (CCC), Medical University of Vienna, Vienna, Austria.

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http://dx.doi.org/10.1002/ijc.32624DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6856680PMC
December 2019

Orthotopic Transplantation of Syngeneic Lung Adenocarcinoma Cells to Study PD-L1 Expression.

J Vis Exp 2019 01 19(143). Epub 2019 Jan 19.

Department of Physiology, Center of Physiology and Pharmacology & Comprehensive Cancer Center (CCC), Medical University of Vienna; Ludwig Boltzmann Institute for Cancer Research (LBI-CR).

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https://www.jove.com/video/58101/orthotopic-transplantation-
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http://dx.doi.org/10.3791/58101DOI Listing
January 2019

Breaking bad family ties: Pan-ERBB blockers inhibit KRAS driven lung tumorigenesis.

Mol Cell Oncol 2018 20;5(6):e1513724. Epub 2018 Sep 20.

Department of Physiology, Center of Physiology and Pharmacology & Comprehensive Cancer Center (CCC), Medical University of Vienna, Vienna, Austria.

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http://dx.doi.org/10.1080/23723556.2018.1513724DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6276852PMC
September 2018

AKT3 drives adenoid cystic carcinoma development in salivary glands.

Cancer Med 2018 02 28;7(2):445-453. Epub 2017 Dec 28.

Department of Physiology, Center of Physiology and Pharmacology, Comprehensive Cancer Center, Medical University of Vienna, Vienna, Austria.

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http://dx.doi.org/10.1002/cam4.1293DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5806106PMC
February 2018

The Transcription Factor ZNF683/HOBIT Regulates Human NK-Cell Development.

Front Immunol 2017 15;8:535. Epub 2017 May 15.

Institute of Vascular Biology and Thrombosis Research, Center of Physiology and Pharmacology, Medical University of Vienna, Vienna, Austria.

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http://dx.doi.org/10.3389/fimmu.2017.00535DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5430038PMC
May 2017

Epidermal growth factor signaling protects from cholestatic liver injury and fibrosis.

J Mol Med (Berl) 2017 01 27;95(1):109-117. Epub 2016 Aug 27.

Institute of Cancer Research, Medical University of Vienna & Comprehensive Cancer Center (CCC), Vienna, Austria.

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http://dx.doi.org/10.1007/s00109-016-1462-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5225179PMC
January 2017

Unexpected oncosuppressive role for STAT3 in KRAS-induced lung tumorigenesis.

Mol Cell Oncol 2016 May 26;3(3):e1036199. Epub 2015 May 26.

Ludwig Boltzmann Institute for Cancer Research (LBI-CR), Vienna, Austria; Institute of Physiology, Center of Physiology and Pharmacology, Comprehensive Cancer Center, Medical University of Vienna, Vienna, Austria.

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http://dx.doi.org/10.1080/23723556.2015.1036199DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4909454PMC
May 2016

Heterologous protein production using euchromatin-containing expression vectors in mammalian cells.

Nucleic Acids Res 2015 Sep 14;43(16):e102. Epub 2015 May 14.

Ludwig Boltzmann Institute for Cancer Research (LBI-CR), Vienna, 1090, Austria Institute of Pharmacology, Center of Physiology and Pharmacology, Comprehensive Cancer Center, Medical University of Vienna, Vienna, 1090, Austria

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http://dx.doi.org/10.1093/nar/gkv475DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4652741PMC
September 2015

Modeling cancer using genetically engineered mice.

Methods Mol Biol 2015 ;1267:3-18

Ludwig Boltzmann Institute for Cancer Research (LBI-CR), Währinger Str. 13a, Vienna, 1090, Austria.

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http://dx.doi.org/10.1007/978-1-4939-2297-0_1DOI Listing
September 2015

Recent advances in recombinant protein production: BAC-based expression vectors, the bigger the better.

Bioengineered 2013 Jul-Aug;4(4):258-61. Epub 2013 Jul 2.

Department of Biotechnology, Vienna Institute of Biotechnology, University of Natural Resources and Life Sciences, Vienna, Vienna, Austria.

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http://dx.doi.org/10.4161/bioe.24060DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3728198PMC
January 2014

Exploration of BAC versus plasmid expression vectors in recombinant CHO cells.

Appl Microbiol Biotechnol 2013 May 19;97(9):4049-54. Epub 2012 Oct 19.

Department of Biotechnology, VIBT, BOKU-University of Natural Resources and Life Sciences (Vienna), Muthgasse 11, 1190 Vienna, Austria.

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http://dx.doi.org/10.1007/s00253-012-4498-xDOI Listing
May 2013

Genetically modified mouse models of cancer invasion and metastasis.

Drug Discov Today Dis Models 2011 1;8(2-3):67-74. Epub 2011 Jul 1.

Ludwig Boltzmann Institute for Cancer Research (LBI-CR) , Währinger Strasse 13a, A-1090 Vienna, Austria.

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http://dx.doi.org/10.1016/j.ddmod.2011.05.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3334252PMC
July 2011

JAK-STAT signaling in hepatic fibrosis.

Front Biosci (Landmark Ed) 2011 Jun 1;16:2794-811. Epub 2011 Jun 1.

Ludwig Boltzmann Institute for Cancer Research, Waehringer Strasse 13a, A-1090 Vienna, Austria.

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http://dx.doi.org/10.2741/3886DOI Listing
June 2011

A novel Ncr1-Cre mouse reveals the essential role of STAT5 for NK-cell survival and development.

Blood 2011 Feb 2;117(5):1565-73. Epub 2010 Dec 2.

Institute of Pharmacology, Center of Physiology and Pharmacology, Medical University of Vienna, Vienna, Austria.

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http://dx.doi.org/10.1182/blood-2010-06-291633DOI Listing
February 2011

A mouse tool for conditional mutagenesis in ovarian granulosa cells.

Genesis 2010 Oct;48(10):612-7

Ludwig Boltzmann Institute for Cancer Research, Vienna, Austria.

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http://dx.doi.org/10.1002/dvg.20664DOI Listing
October 2010

NMDA receptor-dependent GABAB receptor internalization via CaMKII phosphorylation of serine 867 in GABAB1.

Proc Natl Acad Sci U S A 2010 Aug 19;107(31):13924-9. Epub 2010 Jul 19.

Department of Biomedicine, Institute of Physiology, Pharmazentrum, University of Basel, 4056 Basel, Switzerland.

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http://dx.doi.org/10.1073/pnas.1000909107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2922270PMC
August 2010

Stat3 is a negative regulator of intestinal tumor progression in Apc(Min) mice.

Gastroenterology 2010 Mar 4;138(3):1003-11.e1-5. Epub 2009 Dec 4.

Ludwig Boltzmann Institute for Cancer Research, A-1090 Vienna, Austria.

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http://dx.doi.org/10.1053/j.gastro.2009.11.049DOI Listing
March 2010

A Probasin-MerCreMer BAC allows inducible recombination in the mouse prostate.

Genesis 2009 Nov;47(11):757-64

Department of Vascular Biology and Thrombosis Research, Medical University of Vienna, Vienna, Austria.

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http://dx.doi.org/10.1002/dvg.20558DOI Listing
November 2009

A mouse model for visualization of GABA(B) receptors.

Genesis 2009 Sep;47(9):595-602

Department of Biomedicine, Institute of Physiology, University of Basel, Basel, Switzerland.

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http://dx.doi.org/10.1002/dvg.20535DOI Listing
September 2009

Bacterial artificial chromosomes improve recombinant protein production in mammalian cells.

BMC Biotechnol 2009 Jan 14;9. Epub 2009 Jan 14.

Ludwig Boltzmann Institute for Cancer Research (LBI-CR), Währinger Str, 13a, A-1090 Vienna, Austria.

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http://dx.doi.org/10.1186/1472-6750-9-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2653024PMC
January 2009

No evidence for a bone phenotype in GPRC6A knockout mice under normal physiological conditions.

J Mol Endocrinol 2009 Mar 22;42(3):215-23. Epub 2008 Dec 22.

Department of Medicinal Chemistry, Faculty of Pharmaceutical Sciences, University of Copenhagen, Copenhagen, Denmark.

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http://dx.doi.org/10.1677/JME-08-0149DOI Listing
March 2009

Loss of GABAB receptors in cochlear neurons: threshold elevation suggests modulation of outer hair cell function by type II afferent fibers.

J Assoc Res Otolaryngol 2009 Mar 17;10(1):50-63. Epub 2008 Oct 17.

Department of Otology and Laryngology, Harvard Medical School and Eaton-Peabody Laboratory, Massachusetts Eye & Ear Infirmary, 243 Charles St., Boston, MA 02114-3096, USA.

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http://dx.doi.org/10.1007/s10162-008-0138-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2644393PMC
March 2009

PhiC31-mediated cassette exchange into a bacterial artificial chromosome.

Biotechniques 2007 Nov;43(5):659-60, 662, 664

Ludwig Boltzmann Institute for Cancer Research, Vienna, Austria.

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http://dx.doi.org/10.2144/000112592DOI Listing
November 2007

Estimation and visualization of sagittal kinematics of lower limbs orientation using body-fixed sensors.

IEEE Trans Biomed Eng 2006 Jul;53(7):1385-93

Ecole Polytechnique Fédérale de Lausanne (EPFL), Laboratory of Movement Analysis and Measurement, 1015 Lausanne, Switzerland.

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http://dx.doi.org/10.1109/TBME.2006.873678DOI Listing
July 2006

Genetic inactivation of the transcription factor TIF-IA leads to nucleolar disruption, cell cycle arrest, and p53-mediated apoptosis.

Mol Cell 2005 Jul;19(1):77-87

Division of Molecular Biology of the Cell II, German Cancer Research Center, Im Neuenheimer Feld 280, D-69120 Heidelberg, Germany.

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http://dx.doi.org/10.1016/j.molcel.2005.05.023DOI Listing
July 2005

Neuronal migration in the murine rostral migratory stream requires serum response factor.

Proc Natl Acad Sci U S A 2005 Apr 18;102(17):6148-53. Epub 2005 Apr 18.

Department of Molecular Biology, Institute for Cell Biology, Tübingen University, 72076 Tübingen, Germany.

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http://dx.doi.org/10.1073/pnas.0501191102DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1087932PMC
April 2005

Characterization of the promoter of the mouse c-Jun NH2-terminal/stress-activated protein kinase alpha gene.

Biochim Biophys Acta 2004 Nov;1681(1):47-52

Departamento de Bioquímica y Biología Molecular, Facultad de Veterinaria, Universidad de León, Campus de Vegazana s/n. 24007 León, Spain.

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http://dx.doi.org/10.1016/j.bbaexp.2004.10.003DOI Listing
November 2004

Floxed allele for conditional inactivation of the GABAB(1) gene.

Genesis 2004 Nov;40(3):125-30

Pharmazentrum, University of Basel, Department of Clinical-Biological Sciences, Institute of Physiology, CH-4056 Basel, Switzerland.

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http://dx.doi.org/10.1002/gene.20073DOI Listing
November 2004

Generation of a conditional allele of the CBP gene in mouse.

Genesis 2004 Oct;40(2):82-9

Molecular Genetics of Behavior, Max Planck Institute of Psychiatry, Kraepelinstrasse 2-10, 80804 Munich, Germany.

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http://dx.doi.org/10.1002/gene.20068DOI Listing
October 2004

Alpha complementation in the Cre recombinase enzyme.

Genesis 2003 Sep;37(1):25-9

Deutsches Krebsforschungszentrum (DKFZ), Heidelberg, Germany.

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http://dx.doi.org/10.1002/gene.10227DOI Listing
September 2003

ER-based double iCre fusion protein allows partial recombination in forebrain.

Genesis 2002 Nov;34(3):208-14

Deutsches Krebsforschungszentrum, Heidelberg, Germany.

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http://dx.doi.org/10.1002/gene.10153DOI Listing
November 2002

When reverse genetics meets physiology: the use of site-specific recombinases in mice.

FEBS Lett 2002 Oct;529(1):116-21

CNRS FRE2401, Molecular Genetics, Neurophysiology and Behavior, Institute of Biology, Collège de France, 11 place Marcelin Berthelot, 75231 Cedex 5, Paris, France.

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http://dx.doi.org/10.1016/s0014-5793(02)03266-0DOI Listing
October 2002

Construction of a conditional allele of RSK-B/MSK2 in the mouse.

Genesis 2002 Feb;32(2):158-60

Deutsches Krebsforschungszentrum (DKFZ), Heidelberg, Germany.

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http://dx.doi.org/10.1002/gene.10033DOI Listing
February 2002