Publications by authors named "Emile Voest"

100Publications

Learning health care systems: Highly needed but challenging.

Learn Health Syst 2020 Jul 13;4(3):e10211. Epub 2020 Jan 13.

Department of Medical Humanities, Julius Center for Health Sciences and Primary Care University Medical Center Utrecht/Utrecht University Utrecht The Netherlands.

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http://dx.doi.org/10.1002/lrh2.10211DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7362679PMC
July 2020

Enhancing radiation response by a second-generation TRAIL receptor agonist using a new in vitro organoid model system.

Clin Transl Radiat Oncol 2020 Sep 9;24:1-9. Epub 2020 Jun 9.

Division of Cell Biology, The Netherlands Cancer Institute - Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1016/j.ctro.2020.05.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7303921PMC
September 2020

Challenges in Establishing Pure Lung Cancer Organoids Limit Their Utility for Personalized Medicine.

Cell Rep 2020 May;31(5):107588

Department of Molecular Oncology and Immunology, the Netherlands Cancer Institute - Antoni van Leeuwenhoek Hospital, 1066 CX Amsterdam, the Netherlands; Oncode Institute, Utrecht, the Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2020.107588DOI Listing
May 2020

Patients with cancer in the era of 2019 novel coronavirus disease.

Eur J Cancer 2020 06 27;132:125-126. Epub 2020 Apr 27.

Departments of Medical Oncology and Immunology, Netherlands Cancer Institute - Antoni van Leeuwenhoek Hospital, Plesmanlaan 121, 1066 CX, Amsterdam, the Netherlands; Medical Director of the Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX, Amsterdam, the Netherlands.

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http://dx.doi.org/10.1016/j.ejca.2020.03.019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7184997PMC
June 2020

Diverse Gene Fusions Confer Resistance to EGFR-Targeted Therapy via Differential Modulation of BRAF Activity.

Mol Cancer Res 2020 04 7;18(4):537-548. Epub 2020 Jan 7.

Department of Genetics, Center for Molecular Medicine, University Medical Center Utrecht and Utrecht University, Utrecht, the Netherlands.

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http://dx.doi.org/10.1158/1541-7786.MCR-19-0529DOI Listing
April 2020

Tumor organoid-T-cell coculture systems.

Nat Protoc 2020 01 18;15(1):15-39. Epub 2019 Dec 18.

Department of Molecular Oncology and Immunology, The Netherlands Cancer Institute, Antoni van Leeuwenhoek Hospital, Amsterdam, the Netherlands.

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http://dx.doi.org/10.1038/s41596-019-0232-9DOI Listing
January 2020

Advancing molecular tumour boards: highly needed to maximise the impact of precision medicine.

ESMO Open 2019 20;4(2):e000516. Epub 2019 Apr 20.

Department of Molecular Oncology & Immunology, Netherlands Cancer Institute, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1136/esmoopen-2019-000516DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6555597PMC
April 2019

Identifying Epistasis in Cancer Genomes: A Delicate Affair.

Cell 2019 05;177(6):1375-1383

Department of Medicine, University of California, San Diego, La Jolla, CA 92093, USA; Program in Bioinformatics, University of California, San Diego, La Jolla, CA 92093, USA; Department of Bioengineering, University of California, San Diego, La Jolla, CA 92093, USA; Cancer Cell Map Initiative, University of California, San Diego, La Jolla, CA 92093, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2019.05.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6816465PMC
May 2019

[Ethical dilemmas in a general practitioner's clinic due to incidental findings resulting from whole genome sequencing].

Ned Tijdschr Geneeskd 2018 06 15;162. Epub 2018 Jun 15.

UMC Utrecht, afd. Medical Humanities, Julius Centrum.

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June 2018

Evaluation of the HER/PI3K/AKT Family Signaling Network as a Predictive Biomarker of Pathologic Complete Response for Patients With Breast Cancer Treated With Neratinib in the I-SPY 2 TRIAL.

JCO Precis Oncol 2018 16;2. Epub 2018 Aug 16.

, , and , George Mason University, Manassas, VA; , , , , , , , and , University of California, San Francisco, San Francisco, CA; , , and , Netherlands Cancer Institute, Amsterdam, the Netherlands; , University of Pennsylvania, Philadelphia, PA; , University of Texas MD Anderson Cancer Center, Houston; , Berry Consultants, Austin, TX; , University of Minnesota, Minneapolis; and , Mayo Clinic, Rochester, MN.

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http://dx.doi.org/10.1200/PO.18.00024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7446527PMC
August 2018

Unsolicited genomic findings in daily clinical practice

Ned Tijdschr Geneeskd 2018 Jun 15;162. Epub 2018 Jun 15.

UMC Utrecht, afd. Medical Humanities, Julius Centrum.

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June 2018

Detection of endogenously circulating mesenchymal stem cells in human cancer patients.

Int J Cancer 2018 11 17;143(10):2516-2524. Epub 2018 Sep 17.

Division of Molecular Oncology & Immunology, Netherlands Cancer Institute, Amsterdam, The Netherlands.

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http://doi.wiley.com/10.1002/ijc.31727
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http://dx.doi.org/10.1002/ijc.31727DOI Listing
November 2018

Phase I study of combined indomethacin and platinum-based chemotherapy to reduce platinum-induced fatty acids.

Cancer Chemother Pharmacol 2018 05 24;81(5):911-921. Epub 2018 Mar 24.

Division of Molecular Oncology and Immunology, Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1007/s00280-018-3563-2DOI Listing
May 2018

American Society of Clinical Oncology Statement: Biosimilars in Oncology.

J Clin Oncol 2018 04 14;36(12):1260-1265. Epub 2018 Feb 14.

Gary H. Lyman, Hutchinson Institute for Cancer Outcomes Research, Fred Hutchinson Cancer Research Center, Seattle, WA; Edward Balaban, University of Pennsylvania Medical College, Philadelphia, PA; Michael Diaz, Florida Cancer Specialists and Research Institute, St Petersburg, FL; Andrea Ferris, Lungevity Foundation, Bethesda, MD; Anne Tsao, The University of Texas MD Anderson Cancer Center, Houston, TX; Emile Voest, The Netherlands Cancer Institute, Amsterdam, the Netherlands; Robin Zon, Michiana Hematology Oncology, Mishawaka, IN; Michael Francisco, Sybil Green, Shimere Sherwood, and Richard L. Schilsky, American Society of Clinical Oncology, Alexandria, VA; and R. Donald Harvey, Emory University School of Medicine, Atlanta, GA.

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http://dx.doi.org/10.1200/JCO.2017.77.4893DOI Listing
April 2018

Is It Our Duty To Hunt for Pathogenic Mutations?

Trends Mol Med 2018 01 12;24(1):3-6. Epub 2017 Dec 12.

Department of Medical Humanities, Julius Center, University Medical Center, Utrecht, The Netherlands.

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http://dx.doi.org/10.1016/j.molmed.2017.11.008DOI Listing
January 2018

Tumor Organoids as a Pre-clinical Cancer Model for Drug Discovery.

Cell Chem Biol 2017 Sep 27;24(9):1092-1100. Epub 2017 Jul 27.

Department of Molecular Oncology and Immunology, The Netherlands Cancer Institute, Amsterdam, Noord-Holland 1066CX, the Netherlands; Department of Medical Oncology, The Netherlands Cancer Institute, Amsterdam, Noord-Holland 1066CX, the Netherlands; Foundation Hubrecht Organoid Technology (HUB), Utrecht, Utrecht 3584CM, the Netherlands; Cancer Genomics.nl, Utrecht, Utrecht 3584 CG, the Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.chembiol.2017.06.012DOI Listing
September 2017

Fixed Dosing of Monoclonal Antibodies in Oncology.

Oncologist 2017 10 28;22(10):1212-1221. Epub 2017 Jul 28.

Department of Pharmacy & Pharmacology, The Netherlands Cancer Institute and MC Slotervaart, Amsterdam, The Netherlands.

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http://theoncologist.alphamedpress.org/lookup/doi/10.1634/th
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http://dx.doi.org/10.1634/theoncologist.2017-0167DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5634778PMC
October 2017

Intravital characterization of tumor cell migration in pancreatic cancer.

Intravital 2016 18;5(3):e1261773. Epub 2016 Nov 18.

Cancer Genomics Netherlands, Hubrecht Institute-KNAW & University Medical Center Utrecht , Utrecht, the Netherlands.

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http://dx.doi.org/10.1080/21659087.2016.1261773DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5226006PMC
November 2016

ESMO / ASCO Recommendations for a Global Curriculum in Medical Oncology Edition 2016.

Authors:
Christian Dittrich Michael Kosty Svetlana Jezdic Doug Pyle Rossana Berardi Jonas Bergh Nagi El-Saghir Jean-Pierre Lotz Pia Österlund Nicholas Pavlidis Gunta Purkalne Ahmad Awada Susana Banerjee Smita Bhatia Jan Bogaerts Jan Buckner Fatima Cardoso Paolo Casali Edward Chu Julia Lee Close Bertrand Coiffier Roisin Connolly Sarah Coupland Luigi De Petris Maria De Santis Elisabeth G E de Vries Don S Dizon Jennifer Duff Linda R Duska Alexandru Eniu Marc Ernstoff Enriqueta Felip Martin F Fey Jill Gilbert Nicolas Girard Andor W J M Glaudemans Priya K Gopalan Axel Grothey Stephen M Hahn Diana Hanna Christian Herold Jørn Herrstedt Krisztian Homicsko Dennie V Jones Lorenz Jost Ulrich Keilholz Saad Khan Alexander Kiss Claus-Henning Köhne Rainer Kunstfeld Heinz-Josef Lenz Stuart Lichtman Lisa Licitra Thomas Lion Saskia Litière Lifang Liu Patrick J Loehrer Merry Jennifer Markham Ben Markman Marius Mayerhoefer Johannes G Meran Olivier Michielin Elizabeth Charlotte Moser Giannis Mountzios Timothy Moynihan Torsten Nielsen Yuichiro Ohe Kjell Öberg Antonio Palumbo Fedro Alessandro Peccatori Michael Pfeilstöcker Chandrajit Raut Scot C Remick Mark Robson Piotr Rutkowski Roberto Salgado Lidia Schapira Eva Schernhammer Martin Schlumberger Hans-Joachim Schmoll Lowell Schnipper Cristiana Sessa Charles L Shapiro Julie Steele Cora N Sternberg Friedrich Stiefel Florian Strasser Roger Stupp Richard Sullivan Josep Tabernero Luzia Travado Marcel Verheij Emile Voest Everett Vokes Jamie Von Roenn Jeffrey S Weber Hans Wildiers Yosef Yarden

ESMO Open 2016 29;1(5):e000097. Epub 2016 Sep 29.

Department of General Medical Oncology , University Hospitals Leuven , Leuven , Belgium.

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http://dx.doi.org/10.1136/esmoopen-2016-000097DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5070299PMC
September 2016

Cancer genome: highlights of a perspective.

Authors:
Emile Voest

ESMO Open 2016 1;1(3):e000074. Epub 2016 Jun 1.

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http://dx.doi.org/10.1136/esmoopen-2016-000074DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5070300PMC
June 2016

Am I My Family's Keeper? Disclosure Dilemmas in Next-Generation Sequencing.

Hum Mutat 2016 12;37(12):1257-1262

Department of Medical Humanities, Julius Center, University Medical Center Utrecht, Utrecht, The Netherlands.

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http://dx.doi.org/10.1002/humu.23118DOI Listing
December 2016

Genomics- and Transcriptomics-Based Patient Selection for Cancer Treatment With Immune Checkpoint Inhibitors: A Review.

JAMA Oncol 2016 Nov;2(11):1490-1495

Division of Molecular Oncology, Antoni van Leeuwenhoek, Netherlands Cancer Institute, Amsterdam, the Netherlands.

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http://oncology.jamanetwork.com/article.aspx?doi=10.1001/jam
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http://dx.doi.org/10.1001/jamaoncol.2016.2214DOI Listing
November 2016

TAS-102 for Treatment of Advanced Colorectal Cancers That Are No Longer Responding to Other Therapies.

Clin Cancer Res 2016 06 28;22(12):2835-9. Epub 2016 Apr 28.

Department of Molecular Oncology, The Netherlands Cancer Institute, Amsterdam, the Netherlands.

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http://dx.doi.org/10.1158/1078-0432.CCR-15-2783DOI Listing
June 2016

Plasticity between Epithelial and Mesenchymal States Unlinks EMT from Metastasis-Enhancing Stem Cell Capacity.

Cell Rep 2016 Mar 3;14(10):2281-8. Epub 2016 Mar 3.

Cancer Genomics Center-Hubrecht Institute-KNAW & University Medical Centre Utrecht, Uppsalalaan 8, 3584 CT Utrecht, the Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2016.02.034DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4802222PMC
March 2016

DNA-Guided Precision Medicine for Cancer: A Case of Irrational Exuberance?

Cancer Discov 2016 Feb;6(2):130-2

Division of Molecular Carcinogenesis, The Netherlands Cancer Institute, Amsterdam, the Netherlands.

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http://dx.doi.org/10.1158/2159-8290.CD-15-1321DOI Listing
February 2016

Preserved genetic diversity in organoids cultured from biopsies of human colorectal cancer metastases.

Proc Natl Acad Sci U S A 2015 Oct 12;112(43):13308-11. Epub 2015 Oct 12.

Department of Molecular Oncology, The Netherlands Cancer Institute, 1066 CX, Amsterdam, The Netherlands; Cancer Genomics.nl, 3584 CG Utrecht, The Netherlands; Foundation Hubrecht Organoid Technology (HUB), 3584 CT, Utrecht, The Netherlands; Department of Medical Oncology, University Medical Center Utrecht, 3584 CX Utrecht, The Netherlands

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http://dx.doi.org/10.1073/pnas.1516689112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4629330PMC
October 2015

Let Them Eat Fish--Reply.

JAMA Oncol 2015 Sep;1(6):841

Department of Medical Oncology, the Netherlands Cancer Institute, Amsterdam, the Netherlands.

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http://dx.doi.org/10.1001/jamaoncol.2015.2056DOI Listing
September 2015

Increased Plasma Levels of Chemoresistance-Inducing Fatty Acid 16:4(n-3) After Consumption of Fish and Fish Oil.

JAMA Oncol 2015 Jun;1(3):350-8

Department of Medical Oncology, University Medical Center Utrecht, the Netherlands2Department of Molecular Oncology, the Netherlands Cancer Institute, Amsterdam, the Netherlands.

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http://dx.doi.org/10.1001/jamaoncol.2015.0388DOI Listing
June 2015

Effective Therapeutic Intervention and Comprehensive Genetic Analysis of mTOR Signaling in PEComa: A Case Report.

Anticancer Res 2015 Jun;35(6):3399-403

Department of Molecular Oncology, Netherlands Cancer Institute, Amsterdam, the Netherlands.

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June 2015

Towards personalized therapy in pediatric acute lymphoblastic leukemia: RAS mutations and prednisolone resistance.

Haematologica 2015 Apr 5;100(4):e132-6. Epub 2014 Dec 5.

Department of Pediatric Oncology/Hematology, Erasmus Medical Center-Sophia Children's Hospital, Rotterdam Individualized Therapies for Children with Cancer Study Group Dutch Childhood Oncology Group, The Hague, The Netherlands

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http://dx.doi.org/10.3324/haematol.2014.112995DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4380734PMC
April 2015

Simultaneous detection of clinically relevant mutations and amplifications for routine cancer pathology.

J Mol Diagn 2015 Jan 24;17(1):10-8. Epub 2014 Oct 24.

Department of Medical Oncology, University Medical Center Utrecht, Heidelberglaan Utrecht, Utrecht, the Netherlands; Netherlands Center for Personalized Cancer Treatment, Universiteitsweg Utrecht, Utrecht, the Netherlands.

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http://dx.doi.org/10.1016/j.jmoldx.2014.09.004DOI Listing
January 2015

Distinct phosphatases antagonize the p53 response in different phases of the cell cycle.

Proc Natl Acad Sci U S A 2014 May 7;111(20):7313-8. Epub 2014 Apr 7.

Divisions of Cell Biology andCancer Genomics Center, 3584 CG, Utrecht, The Netherlands; and

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http://dx.doi.org/10.1073/pnas.1322021111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4034242PMC
May 2014

American Society of Clinical Oncology perspective: Raising the bar for clinical trials by defining clinically meaningful outcomes.

J Clin Oncol 2014 Apr 17;32(12):1277-80. Epub 2014 Mar 17.

Lee M. Ellis, University of Texas MD Anderson Cancer Center, Houston, TX; David S. Bernstein and Richard L. Schilsky, American Society of Clinical Oncology, Alexandria, VA; Emile E. Voest, University Medical Center Utrecht, Utrecht, the Netherlands; Jordan D. Berlin, Vanderbilt-Ingram Cancer Center, Nashville, TN; Daniel Sargent, Mayo Clinic, Rochester, MN; Patricia Cortazar, US Food and Drug Administration, Silver Spring, MD; Elizabeth Garrett-Mayer, Medical University of South Carolina, Charleston, SC; Roy S. Herbst and Rogerio C. Lilenbaum, Yale Cancer Center, New Haven, CT; Camelia Sima and Mithat Gonen, Memorial Sloan-Kettering Cancer Center, New York, NY; Alan P. Venook, Helen Diller Family Comprehensive Cancer Center at University of California San Francisco, San Francisco, CA; Neal J. Meropol, University Hospitals Seidman Cancer Center, Case Comprehensive Cancer Center, Case Western Reserve University, Cleveland, OH; Lowell E. Schnipper, Beth Israel Deaconess Medical Center, Boston, MA.

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http://jco.ascopubs.org/content/early/2014/03/14/JCO.2013.53
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http://jco.ascopubs.org/cgi/doi/10.1200/JCO.2013.53.8009
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http://dx.doi.org/10.1200/JCO.2013.53.8009DOI Listing
April 2014

[Drug research in oncology; advances in the genome era].

Ned Tijdschr Geneeskd 2014 ;158:A6801

Center for Personalised Cancer Treatment.

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November 2014

Tumor heterogeneity and personalized cancer medicine: are we being outnumbered?

Future Oncol 2014 Feb;10(3):417-28

Department of Medical Oncology, University Medical Center Utrecht, Heidelberglaan 100, 3584 CX Utrecht, The Netherlands.

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http://dx.doi.org/10.2217/fon.13.214DOI Listing
February 2014

Reply to L. Battistuzzi et Al.

J Clin Oncol 2013 Nov 7;31(32):4165-6. Epub 2013 Oct 7.

University Medical Center Utrecht, Utrecht, the Netherlands.

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http://dx.doi.org/10.1200/JCO.2013.52.2755DOI Listing
November 2013

Gain-of-function mutations of PPM1D/Wip1 impair the p53-dependent G1 checkpoint.

J Cell Biol 2013 May 6;201(4):511-21. Epub 2013 May 6.

Institute of Biochemistry and Experimental Oncology, First Faculty of Medicine, Charles University in Prague, CZ-12853 Prague, Czech Republic.

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http://dx.doi.org/10.1083/jcb.201210031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3653305PMC
May 2013

The host immunological response to cancer therapy: An emerging concept in tumor biology.

Exp Cell Res 2013 Jul 19;319(11):1687-95. Epub 2013 Mar 19.

Department of Molecular Pharmacology, Rappaport Faculty of Medicine and the Rappaport Institute, Technion-Israel Institute of Technology, 1 Efron Street, Bat Galim, Haifa 31096, Israel. Electronic address:

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http://dx.doi.org/10.1016/j.yexcr.2013.03.007DOI Listing
July 2013

Development and validation of a quantitative LC-tandem MS assay for hexadeca-4,7,10,13-tetraenoic acid in human and mouse plasma.

J Chromatogr B Analyt Technol Biomed Life Sci 2013 Apr 24;925:16-9. Epub 2013 Jan 24.

University Medical Centre Utrecht, Department of Metabolic Diseases and Netherlands Metabolomics Centre, Lundlaan 6, 3584 EA Utrecht, The Netherlands.

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https://linkinghub.elsevier.com/retrieve/pii/S15700232130005
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http://dx.doi.org/10.1016/j.jchromb.2013.01.012DOI Listing
April 2013

Reduced cilia frequencies in human renal cell carcinomas versus neighboring parenchymal tissue.

Cilia 2013 Jan 31;2(1). Epub 2013 Jan 31.

Department of Nephrology and Hypertension, University Medical Center Utrecht, Heidelberglaan 100, 3584, CX, Utrecht, The Netherlands.

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http://dx.doi.org/10.1186/2046-2530-2-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3564780PMC
January 2013

Identification of high-confidence somatic mutations in whole genome sequence of formalin-fixed breast cancer specimens.

Nucleic Acids Res 2012 Aug 6;40(14):e107. Epub 2012 Apr 6.

Moores UCSD Cancer Center, Bioinformatics and Systems Biology Graduate Program, Department of Pediatrics and Rady Children's Hospital, University of California San Diego, 9500 Gilman Drive, La Jolla, CA 92093, USA.

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http://dx.doi.org/10.1093/nar/gks299DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3413110PMC
August 2012

Symptoms tell it all: a systematic review of the value of symptom assessment to predict survival in advanced cancer patients.

Crit Rev Oncol Hematol 2012 Oct 31;84(1):130-48. Epub 2012 Mar 31.

Department of Medical Oncology, University Medical Center Utrecht, PO Box 85500, 3508 GA Utrecht, The Netherlands.

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http://dx.doi.org/10.1016/j.critrevonc.2012.02.011DOI Listing
October 2012