Publications by authors named "Emanuele Bosi"

100Publications

Frequency of flash glucose monitoring readings, hemoglobin A1c and time in range: a real life study in adults with type 1 diabetes.

Acta Diabetol 2020 Nov 27;57(11):1395-1397. Epub 2020 Jul 27.

Department of Internal Medicine, IRCCS San Raffaele Scientific Institute, Milan, Italy.

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http://dx.doi.org/10.1007/s00592-020-01577-7DOI Listing
November 2020

Expression of glucose transporters in duodenal mucosa of patients with type 1 diabetes.

Acta Diabetol 2020 Nov 2;57(11):1367-1373. Epub 2020 Jul 2.

Diabetes Research Institute, IRCCS San Raffaele Hospital, 20132, Milan, Italy.

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http://dx.doi.org/10.1007/s00592-020-01558-wDOI Listing
November 2020

A direct look at the dysfunction and pathology of the β cells in human type 2 diabetes.

Semin Cell Dev Biol 2020 07 13;103:83-93. Epub 2020 May 13.

Department of Clinical and Experimental Medicine - University of Pisa, Via Savi 10, Pisa, Italy.

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http://dx.doi.org/10.1016/j.semcdb.2020.04.005DOI Listing
July 2020

Extracellular Vesicles Derived Human-miRNAs Modulate the Immune System in Type 1 Diabetes.

Front Cell Dev Biol 2020 31;8:202. Epub 2020 Mar 31.

Department of Pediatric Endocrinology, Diabetes and Metabolic Diseases, University Children's Hospital, University Medical Centre Ljubljana, Ljubljana, Slovenia.

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http://dx.doi.org/10.3389/fcell.2020.00202DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7136501PMC
March 2020

Cervix neuroendocrine carcinoma presenting with severe hypokalemia and Cushing's syndrome.

Endocrine 2020 02 22;67(2):318-320. Epub 2020 Jan 22.

Internal Medicine, Diabetes and Endocrinology Unit, San Raffaele Hospital and Scientific Institute, San Raffaele Vita Salute University, Milano, Italy.

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http://dx.doi.org/10.1007/s12020-020-02202-xDOI Listing
February 2020

Treatment with rapamycin can restore regulatory T-cell function in IPEX patients.

J Allergy Clin Immunol 2020 Apr 23;145(4):1262-1271.e13. Epub 2019 Dec 23.

San Raffaele Telethon Institute for Gene Therapy (SR-Tiget), IRCCS San Raffaele Scientific Institute, Milan, Italy; Department of Pediatrics, Division of Stem Cell Transplantation and Regenerative Medicine, Stanford University School of Medicine, Stanford, Calif. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2019.11.043DOI Listing
April 2020

Epigenetic patterns within the haplotype phased fig (Ficus carica L.) genome.

Plant J 2020 05 11;102(3):600-614. Epub 2020 Jan 11.

Department of Agriculture, Food and Environment, University of Pisa, Pisa, Italy.

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http://dx.doi.org/10.1111/tpj.14635DOI Listing
May 2020

Less Is More: Genome Reduction and the Emergence of Cooperation-Implications into the Coevolution of Microbial Communities.

Int J Genomics 2019 17;2019:2659175. Epub 2019 Feb 17.

Department of Agriculture, Food and Environment (DAFE), University of Pisa, Italy.

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https://www.hindawi.com/journals/ijg/2019/2659175/
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http://dx.doi.org/10.1155/2019/2659175DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6398007PMC
February 2019

Guido Pozza M.D.: a visionary scholar.

Acta Diabetol 2019 Jan;56(1):3-5

Dipartimento di Scienze della Salute, Università degli Studi di Milano, Milan, Italy.

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http://dx.doi.org/10.1007/s00592-018-1269-xDOI Listing
January 2019

A novel LIPS assay for insulin autoantibodies.

Acta Diabetol 2018 Mar 5;55(3):263-270. Epub 2018 Jan 5.

Human Pathology Genomic Diagnostics Unit, Division of Genetics and Cell Biology, IRCCS San Raffaele Scientific Institute, Via Olgettina 60, 20132, Milan, Italy.

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http://dx.doi.org/10.1007/s00592-017-1082-yDOI Listing
March 2018

Integration of Comparative Genomics with Genome-Scale Metabolic Modeling to Investigate Strain-Specific Phenotypical Differences.

Methods Mol Biol 2018 ;1716:151-175

Department of Biology, University of Florence, Sesto Fiorentino, Italy.

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http://dx.doi.org/10.1007/978-1-4939-7528-0_7DOI Listing
July 2018

Gian Franco Bottazzo, 1946-2017.

Diabetologia 2018 01;61(1):3-5

Department of Immunobiology, Blizard Institute, Queen Mary University of London, London, UK.

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http://dx.doi.org/10.1007/s00125-017-4486-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6448950PMC
January 2018

Subfunctionalization influences the expansion of bacterial multidrug antibiotic resistance.

BMC Genomics 2017 Oct 30;18(1):834. Epub 2017 Oct 30.

Department of Biology, University of Florence, Via Madonna del Piano 6, 50019, Sesto Fiorentino, FI, Italy.

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http://dx.doi.org/10.1186/s12864-017-4222-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5663151PMC
October 2017

Autoantibody binding in liquid phase to IL-2 in human sera is not type 1 diabetes specific.

Diabetologia 2017 09 19;60(9):1834-1835. Epub 2017 Jul 19.

Division of Genetics and Cell Biology, IRCCS San Raffaele Scientific Institute, Via Olgettina 60, 20132, Milan, Italy.

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http://dx.doi.org/10.1007/s00125-017-4376-2DOI Listing
September 2017

Perspectives and Challenges in Microbial Communities Metabolic Modeling.

Front Genet 2017 21;8:88. Epub 2017 Jun 21.

Department of Biology, University of FlorenceFlorence, Italy.

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http://dx.doi.org/10.3389/fgene.2017.00088DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5478693PMC
June 2017

The pangenome of (Antarctic) Pseudoalteromonas bacteria: evolutionary and functional insights.

BMC Genomics 2017 01 17;18(1):93. Epub 2017 Jan 17.

Laboratory of Microbial and Molecular Evolution, Department of Biology, University of Florence, Via Madonna del Piano 6, I-501019, Sesto F.no Florence, Italy.

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http://dx.doi.org/10.1186/s12864-016-3382-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5240218PMC
January 2017

Modelling microbial metabolic rewiring during growth in a complex medium.

BMC Genomics 2016 11 24;17(1):970. Epub 2016 Nov 24.

Department of Biology, University of Florence, Via Madonna del Piano 6, I-50019, Sesto F.no, Italy.

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http://dx.doi.org/10.1186/s12864-016-3311-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5121958PMC
November 2016

Insulin resistance is associated with the aggressiveness of pancreatic ductal carcinoma.

Acta Diabetol 2016 Dec 23;53(6):945-956. Epub 2016 Aug 23.

Diabetes Research Institute, IRCCS San Raffaele Scientific Institute, Via Olgettina 60, 20132, Milan, Italy.

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http://dx.doi.org/10.1007/s00592-016-0893-6DOI Listing
December 2016

The evolving frontier of diabetes therapy: The renaissance of glycemology.

Diabetes Res Clin Pract 2016 Aug 20;118:168-71. Epub 2016 Jun 20.

Diabetes Research Institute, San Raffaele Hospital and San Raffaele Vita-Salute University, Milan, Italy.

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http://dx.doi.org/10.1016/j.diabres.2016.04.036DOI Listing
August 2016

Comparative genome-scale modelling of Staphylococcus aureus strains identifies strain-specific metabolic capabilities linked to pathogenicity.

Proc Natl Acad Sci U S A 2016 06 10;113(26):E3801-9. Epub 2016 Jun 10.

Department of Bioengineering, University of California, San Diego, La Jolla, CA 92093-0412; Department of Pediatrics, University of California, San Diego, La Jolla, CA 92093-0760;

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http://dx.doi.org/10.1073/pnas.1523199113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4932939PMC
June 2016

"Every Gene Is Everywhere but the Environment Selects": Global Geolocalization of Gene Sharing in Environmental Samples through Network Analysis.

Genome Biol Evol 2016 05 13;8(5):1388-400. Epub 2016 May 13.

Department of Biology, National University of Ireland Maynooth, County Kildare, Ireland Computational Evolutionary Biology, Faculty of Life Sciences, The University of Manchester, United Kingdom

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http://dx.doi.org/10.1093/gbe/evw077DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4898794PMC
May 2016

Pharmacogenetic influence of eNOS gene variant on endothelial and glucose metabolism responses to L-arginine supplementation: Post hoc analysis of the L-arginine trial.

Metabolism 2015 Nov 28;64(11):1582-91. Epub 2015 Aug 28.

Cardio-Metabolism and Clinical Trials Unit, Diabetes Research Institute, Department of Internal Medicine,IRCCS San Raffaele Hospital, Milan, Italy.

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http://dx.doi.org/10.1016/j.metabol.2015.08.015DOI Listing
November 2015

Successful Treatment of Dercum's Disease by Transcutaneous Electrical Stimulation: A Case Report.

Medicine (Baltimore) 2015 Jun;94(24):e950

From the Diabetes Research Institute (SM, MS, EB); Department of Radiology, San Raffaele Hospital and Scientific Institute (CL); and San Raffaele Vita Salute University, Milan, Italy (AC, EB).

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http://pdfs.journals.lww.com/md-journal/2015/06030/Successfu
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http://dx.doi.org/10.1097/MD.0000000000000950DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4616524PMC
June 2015

Antagonistic interactions between endophytic cultivable bacterial communities isolated from the medicinal plant Echinacea purpurea.

Environ Microbiol 2016 09 22;18(8):2357-65. Epub 2015 Jul 22.

Department of Biology, University of Florence, Via Madonna del Piano 6, Sesto Fiorentino, Florence, I-50019, Italy.

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http://dx.doi.org/10.1111/1462-2920.12911DOI Listing
September 2016

MeDuSa: a multi-draft based scaffolder.

Bioinformatics 2015 Aug 25;31(15):2443-51. Epub 2015 Mar 25.

Department of Biology, ComBo, Florence Computational Biology Group, Department of Biology, LEMM, Laboratory of Microbial and Molecular Evolution Florence, University of Florence, I-50019 Sesto F.no, Italy.

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http://dx.doi.org/10.1093/bioinformatics/btv171DOI Listing
August 2015

Defining orthologs and pangenome size metrics.

Methods Mol Biol 2015 ;1231:191-202

Department of Biology, University of Florence, via Madonna del Piano 6, Sesto Fiorentino, Florence, 50019, Italy,

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http://dx.doi.org/10.1007/978-1-4939-1720-4_13DOI Listing
June 2015

Improvement in clinical symptoms of scleredema diabeticorum by frequency-modulated electromagnetic neural stimulation: a case report.

Diabetes Care 2014 Nov;37(11):e233-4

Diabetes Research Institute, San Raffaele Scientific Institute and Vita-Salute San Raffaele University, Milan, Italy

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http://dx.doi.org/10.2337/dc14-0730DOI Listing
November 2014

High GADA titer increases the risk of insulin requirement in LADA patients: a 7-year follow-up (NIRAD study 7).

Eur J Endocrinol 2014 Dec 11;171(6):697-704. Epub 2014 Sep 11.

Department of Experimental Medicine'Sapienza' University of Rome, Viale Regina Elena 324, 00161 Rome, ItalyDepartment of Internal MedicineS. Michele Hospital, Cagliari, ItalyEndocrinologyGaribaldi di Nesima Hospital, Catania University, Catania, ItalyDiabetologic CenterDistretto 54 ASL Napoli 3, Naples, ItalyEndocrinology and DiabetesDepartment of Medical Sciences, University of Cagliari, Cagliari, ItalyU.O.C. Diabetologia/Endocrinology'A. Cardarelli' Hospital, Campobasso, ItalyDepartment of Public Health Sciences and Infectious Diseases'Sapienza' University of Rome, Rome, ItalySan Raffaele Scientific InstituteDiabetes Research Institute, Milan, ItalySection of Internal MedicineEndocrinology, Andrology and Metabolic Disease, Department of Emergency and Organ Transplantation, University of Bari, School of Medicine, Bari, Italy

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http://www.eje-online.org/content/early/2014/09/11/EJE-14-03
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http://www.eje-online.org/content/171/6/697.full.pdf
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http://www.eje-online.org/cgi/doi/10.1530/EJE-14-0342
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http://dx.doi.org/10.1530/EJE-14-0342DOI Listing
December 2014

Smoking is associated with impaired glucose regulation and a decrease in insulin sensitivity and the disposition index in first-degree relatives of type 2 diabetes subjects independently of the presence of metabolic syndrome.

Acta Diabetol 2014 Oct 17;51(5):793-9. Epub 2014 Jun 17.

Cardio-Metabolism and Clinical Trials Unit, Diabetes Research Institute, Division of Immunology, Transplantation and Infective Diseases, Department of Internal Medicine, IRCCS San Raffaele, Milan, Italy,

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http://dx.doi.org/10.1007/s00592-014-0599-6DOI Listing
October 2014

Identification of novel genetic Loci associated with thyroid peroxidase antibodies and clinical thyroid disease.

Authors:
Marco Medici Eleonora Porcu Giorgio Pistis Alexander Teumer Suzanne J Brown Richard A Jensen Rajesh Rawal Greet L Roef Theo S Plantinga Sita H Vermeulen Jari Lahti Matthew J Simmonds Lise Lotte N Husemoen Rachel M Freathy Beverley M Shields Diana Pietzner Rebecca Nagy Linda Broer Layal Chaker Tim I M Korevaar Maria Grazia Plia Cinzia Sala Uwe Völker J Brent Richards Fred C Sweep Christian Gieger Tanguy Corre Eero Kajantie Betina Thuesen Youri E Taes W Edward Visser Andrew T Hattersley Jürgen Kratzsch Alexander Hamilton Wei Li Georg Homuth Monia Lobina Stefano Mariotti Nicole Soranzo Massimiliano Cocca Matthias Nauck Christin Spielhagen Alec Ross Alice Arnold Martijn van de Bunt Sandya Liyanarachchi Margit Heier Hans Jörgen Grabe Corrado Masciullo Tessel E Galesloot Ee M Lim Eva Reischl Peter J Leedman Sandra Lai Alessandro Delitala Alexandra P Bremner David I W Philips John P Beilby Antonella Mulas Matteo Vocale Goncalo Abecasis Tom Forsen Alan James Elisabeth Widen Jennie Hui Holger Prokisch Ernst E Rietzschel Aarno Palotie Peter Feddema Stephen J Fletcher Katharina Schramm Jerome I Rotter Alexander Kluttig Dörte Radke Michela Traglia Gabriela L Surdulescu Huiling He Jayne A Franklyn Daniel Tiller Bijay Vaidya Tim de Meyer Torben Jørgensen Johan G Eriksson Peter C O'Leary Eric Wichmann Ad R Hermus Bruce M Psaty Till Ittermann Albert Hofman Emanuele Bosi David Schlessinger Henri Wallaschofski Nicola Pirastu Yurii S Aulchenko Albert de la Chapelle Romana T Netea-Maier Stephen C L Gough Henriette Meyer Zu Schwabedissen Timothy M Frayling Jean-Marc Kaufman Allan Linneberg Katri Räikkönen Johannes W A Smit Lambertus A Kiemeney Fernando Rivadeneira André G Uitterlinden John P Walsh Christa Meisinger Martin den Heijer Theo J Visser Timothy D Spector Scott G Wilson Henry Völzke Anne Cappola Daniela Toniolo Serena Sanna Silvia Naitza Robin P Peeters

PLoS Genet 2014 Feb 27;10(2):e1004123. Epub 2014 Feb 27.

Department of Internal Medicine, Erasmus Medical Center Rotterdam, Rotterdam, The Netherlands.

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http://repub.eur.nl/pub/65428/REPUB_65428_OA.pdf
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http://dx.plos.org/10.1371/journal.pgen.1004123
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http://dx.doi.org/10.1371/journal.pgen.1004123DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3937134PMC
February 2014

Draft genomes of three Antarctic Psychrobacter strains producing antimicrobial compounds against Burkholderia cepacia complex, opportunistic human pathogens.

Mar Genomics 2014 Feb 5;13:37-8. Epub 2014 Jan 5.

Laboratory of Microbial and Molecular Evolution, Department of Biology, University of Florence, Via Madonna del Piano 6, 50019 Sesto Fiorentino, Firenze, Italy.

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http://dx.doi.org/10.1016/j.margen.2013.12.009DOI Listing
February 2014

Genomic analysis of three sponge-associated Arthrobacter Antarctic strains, inhibiting the growth of Burkholderia cepacia complex bacteria by synthesizing volatile organic compounds.

Microbiol Res 2014 Jul-Aug;169(7-8):593-601. Epub 2013 Oct 20.

Laboratory of Microbial and Molecular Evolution, Department of Biology, University of Florence, Via Madonna del Piano 6, 50019 Sesto Fiorentino, Firenze, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.micres.2013.09.018DOI Listing
December 2014

Glucose variability: An emerging target for the treatment of diabetes mellitus.

Diabetes Res Clin Pract 2013 Nov 25;102(2):86-95. Epub 2013 Sep 25.

Dipartimento di Medicina dei Sistemi, Università degli Studi di Roma "Tor Vergata", Italy.

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http://dx.doi.org/10.1016/j.diabres.2013.09.007DOI Listing
November 2013

Draft Genome Sequence of the Fast-Growing Bacterium Vibrio natriegens Strain DSMZ 759.

Genome Announc 2013 Aug 22;1(4). Epub 2013 Aug 22.

Laboratory of Microbial and Molecular Evolution, Department of Biology, University of Florence, Florence, Italy.

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http://dx.doi.org/10.1128/genomeA.00648-13DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3751608PMC
August 2013

L-arginine enriched biscuits improve endothelial function and glucose metabolism: a pilot study in healthy subjects and a cross-over study in subjects with impaired glucose tolerance and metabolic syndrome.

Metabolism 2013 Feb 3;62(2):255-64. Epub 2012 Oct 3.

Cardio-Diabetes and Core Lab Unit, Metabolic and Cardiovascular Science Division, San Raffaele Scientific Institute, Milan, Italy.

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http://dx.doi.org/10.1016/j.metabol.2012.08.004DOI Listing
February 2013

GADA titer-related risk for organ-specific autoimmunity in LADA subjects subdivided according to gender (NIRAD study 6).

J Clin Endocrinol Metab 2012 Oct 3;97(10):3759-65. Epub 2012 Aug 3.

Department of Internal Medicine and Medical Specialties, Sapienza University, Viale del Policlinico 155, 00161 Rome, Italy.

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http://dx.doi.org/10.1210/jc.2012-2037DOI Listing
October 2012

Gastroenteric neuroendocrine neoplasms classification: comparison of prognostic models.

Cancer 2013 Jan 28;119(1):36-44. Epub 2012 Jun 28.

Department of Endocrinology and Internal Medicine, Endocrine Tumors Unit, San Raffaele Scientific Institute, Milan, Italy.

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http://doi.wiley.com/10.1002/cncr.27716
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http://dx.doi.org/10.1002/cncr.27716DOI Listing
January 2013

Insulin resistance/hyperinsulinemia and cancer mortality: the Cremona study at the 15th year of follow-up.

Acta Diabetol 2012 Dec 4;49(6):421-8. Epub 2012 Jan 4.

Division of Metabolic and Cardiovascular Sciences, Istituto Scientifico H San Raffaele, Milan, Italy.

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http://dx.doi.org/10.1007/s00592-011-0361-2DOI Listing
December 2012

Aerobic and resistance training effects compared to aerobic training alone in obese type 2 diabetic patients on diet treatment.

Diabetes Res Clin Pract 2011 Dec 3;94(3):395-403. Epub 2011 Sep 3.

San Raffaele Scientific Institute, Cardio-Metabolic and Clinical Trials Unit, Internal Medicine Department, and Metabolic and Cardiovascular Science Division, Milan 20132, Italy.

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http://dx.doi.org/10.1016/j.diabres.2011.08.002DOI Listing
December 2011

The mosaicism of plasmids revealed by atypical genes detection and analysis.

BMC Genomics 2011 Aug 8;12:403. Epub 2011 Aug 8.

Lab, of Microbial and Molecular Evolution, Dept, of Evolutionary Biology, University of Florence, Italy.

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http://dx.doi.org/10.1186/1471-2164-12-403DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3166947PMC
August 2011

Defective differentiation of regulatory FoxP3+ T cells by small-intestinal dendritic cells in patients with type 1 diabetes.

Diabetes 2011 Aug 6;60(8):2120-4. Epub 2011 Jun 6.

Experimental Diabetes Unit, Division of Immunology, Transplantation, and Infectious Diseases, San Raffaele Scientific Institute, Milan, Italy.

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http://dx.doi.org/10.2337/db10-1201DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3142071PMC
August 2011

Long-lasting remission of type 1 diabetes following treatment with topiramate for generalized seizures.

Acta Diabetol 2012 Feb 19;49(1):75-9. Epub 2011 Feb 19.

Department of Internal Medicine, Diabetes and Endocrinology Unit, San Raffaele Scientific Institute, Milan, Italy.

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http://link.springer.com/10.1007/s00592-011-0268-y
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http://dx.doi.org/10.1007/s00592-011-0268-yDOI Listing
February 2012

Multiple outcomes associated with the use of metformin and sulphonylureas in type 2 diabetes: a population-based cohort study in Italy.

Eur J Clin Pharmacol 2011 Mar 19;67(3):289-99. Epub 2010 Nov 19.

Unit of Biostatistics and Epidemiology, Department of Statistics, University of Milano-Bicocca, Via Bicocca degli Arcimboldi, 8, Edificio U7, 20126, Milan, Italy.

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http://dx.doi.org/10.1007/s00228-010-0939-6DOI Listing
March 2011

Diagnostic sensitivity of thyroid autoantibodies assessed in a population-based, cross-sectional study in adults.

Auto Immun Highlights 2010 Nov 4;1(2):83-6. Epub 2010 Nov 4.

General Medicine, Diabetes & Endocrinology Unit, San Raffaele Scientific Institute and Vita Salute San Raffaele University, Via Olgettina, 60, 20132 Milan, Italy.

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http://dx.doi.org/10.1007/s13317-010-0012-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4389046PMC
November 2010

Time for testing incretin therapies in early type 1 diabetes?

Authors:
Emanuele Bosi

J Clin Endocrinol Metab 2010 Jun;95(6):2607-9

Department of Internal Medicine, San Raffaele Scientific Institute and Vita Salute San Raffaele University, 20132 Milan, Italy.

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http://dx.doi.org/10.1210/jc.2009-2741DOI Listing
June 2010

Fasting hyperinsulinemia associates with increased sub-clinical inflammation in first-degree relatives normal glucose tolerant women independently of the metabolic syndrome.

Diabetes Metab Res Rev 2009 Oct;25(7):639-46

Cardio-Metabolic and Clinical Trials Unit and Cardiodiabetes & Core-Lab, Metabolic and Cardiovascular Science Division and Internal Medicine Department, San Raffaele Scientific Institute, Milan, Italy.

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http://dx.doi.org/10.1002/dmrr.1003DOI Listing
October 2009