Emanuela Falcinelli

Emanuela Falcinelli

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Emanuela Falcinelli

Emanuela Falcinelli

Publications by authors named "Emanuela Falcinelli"

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Inherited platelet disorders in women.

Thromb Res 2019 Sep;181 Suppl 1:S54-S59

Department of Medicine, Section of Internal and Cardiovascular Medicine, University of Perugia, Perugia, Italy.

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http://dx.doi.org/10.1016/S0049-3848(19)30368-8DOI Listing
September 2019

Inhibition of platelet function after ocular administration of non-steroidal anti-inflammatory drugs.

Thromb Res 2019 Mar 11;175:1-5. Epub 2019 Jan 11.

Department of Medicine, Section of Internal and Cardiovascular Medicine, University of Perugia, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.thromres.2019.01.005DOI Listing
March 2019

Platelet function assays in diagnosis: an update.

Expert Rev Hematol 2019 Jan 16;12(1):29-46. Epub 2019 Jan 16.

a Department of Medicine, Section of Internal and Cardiovascular Medicine , University of Perugia , Perugia , Italy.

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http://dx.doi.org/10.1080/17474086.2019.1562333DOI Listing
January 2019

Effect of aspirin treatment on abacavir-associated platelet hyperreactivity in HIV-infected patients.

Int J Cardiol 2018 07 12;263:118-124. Epub 2018 Apr 12.

Department of Medicine, Section of Internal and Cardiovascular Medicine, University Perugia, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.ijcard.2018.04.052DOI Listing
July 2018

Increase of von Willebrand factor with aging in type 1 von Willebrand disease: fact or fiction?

Haematologica 2017 11 27;102(11):e431-e433. Epub 2017 Jul 27.

Department of Medicine, Section of Internal and Cardiovascular Medicine, University of Perugia, Italy

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http://dx.doi.org/10.3324/haematol.2017.168013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5664402PMC
November 2017

Platelets Contribute to the Accumulation of Matrix Metalloproteinase Type 2 in Synovial Fluid in Osteoarthritis.

Thromb Haemost 2017 11 30;117(11):2116-2124. Epub 2017 Nov 30.

Rheumatology Unit, Department of Medicine, University of Perugia, Perugia, Italy.

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http://dx.doi.org/10.1160/TH17-06-0379DOI Listing
November 2017

Endothelial activation in patients with superficial vein thrombosis (SVT) of the lower limbs.

Thromb Res 2017 09 27;157:20-22. Epub 2017 Jun 27.

Section of Internal and Cardiovascular Medicine, Dept. of Internal Medicine, University of Perugia, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.thromres.2017.06.033DOI Listing
September 2017

Matrix Metalloproteinases and Platelet Function.

Prog Mol Biol Transl Sci 2017 21;147:133-165. Epub 2017 Mar 21.

Section of Internal and Cardiovascular Medicine, University of Perugia, Perugia, Italy.

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http://dx.doi.org/10.1016/bs.pmbts.2017.01.002DOI Listing
July 2017

Platelet amyloid precursor protein is a modulator of venous thromboembolism in mice.

Blood 2017 07 13;130(4):527-536. Epub 2017 Jun 13.

Department of Biology and Biotechnology, University of Pavia, Pavia, Italy; and.

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http://dx.doi.org/10.1182/blood-2017-01-764910DOI Listing
July 2017

A novel mechanism regulating human platelet activation by MMP-2-mediated PAR1 biased signaling.

Blood 2017 02 29;129(7):883-895. Epub 2016 Dec 29.

Division of Internal and Cardiovascular Medicine, Department of Medicine, University of Perugia, Perugia, Italy; and.

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http://dx.doi.org/10.1182/blood-2016-06-724245DOI Listing
February 2017

Inherited platelet function disorders. Diagnostic approach and management.

Hamostaseologie 2016 Nov 3;36(4):265-278. Epub 2016 Aug 3.

Paolo Gresele, MD, PhD, Division of Internal and Cardiovascular Medicine Department of Medicine, University of Perugia, Via E. dal Pozzo, 06126 Perugia, Italy, Tel. +39/07 55 78 39 89, Fax +39/07 55 71 60 83, E-Mail:

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http://dx.doi.org/10.5482/HAMO-16-02-0002DOI Listing
November 2016

Inherited Platelet Function Disorders: Algorithms for Phenotypic and Genetic Investigation.

Semin Thromb Hemost 2016 Apr 10;42(3):292-305. Epub 2016 Mar 10.

Division of Internal and Cardiovascular Medicine, Department of Medicine, University of Perugia, Perugia, Italy.

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http://dx.doi.org/10.1055/s-0035-1570078DOI Listing
April 2016

Cytoskeletal perturbation leads to platelet dysfunction and thrombocytopenia in variant forms of Glanzmann thrombasthenia.

Haematologica 2016 Jan 9;101(1):46-56. Epub 2015 Oct 9.

Department of Medicine, Section of Internal and Cardiovascular Medicine, University of Perugia, Italy

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http://dx.doi.org/10.3324/haematol.2015.130849DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4697891PMC
January 2016

Matrix metalloproteinase-2 enhances platelet deposition on collagen under flow conditions.

Thromb Haemost 2016 Jan 29;115(2):333-43. Epub 2015 Oct 29.

Paolo Gresele, MD, PhD, Section of Internal and Cardiovascular Medicine, Department of Medicine, University of Perugia, Via E. Dal Pozzo, 06126 Perugia, Italy, Tel.: +39 075 5783989, Fax: +39 075 5716083, E-mail:

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http://dx.doi.org/10.1160/TH15-04-0300DOI Listing
January 2016

Analysis of 339 pregnancies in 181 women with 13 different forms of inherited thrombocytopenia.

Haematologica 2014 Aug 24;99(8):1387-94. Epub 2014 Apr 24.

Department of Medicine and Haematology, University Hospital of Verona, Verona, Italy.

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http://dx.doi.org/10.3324/haematol.2014.105924DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116839PMC
August 2014

Highly active antiretroviral therapy-related mechanisms of endothelial and platelet function alterations.

Rev Cardiovasc Med 2014 ;15 Suppl 1:S9-20

Division of Internal and Cardiovascular Medicine and Division of Infectious Disease, Department of Medicine, University of Perugia, Perugia, Italy.

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August 2014

Matrix metalloproteinase-2 of human carotid atherosclerotic plaques promotes platelet activation. Correlation with ischaemic events.

Thromb Haemost 2014 Jun 6;111(6):1089-101. Epub 2014 Feb 6.

Paolo Gresele, MD, PhD, Dept. of Internal Medicine, Section of Internal and Cardiovascular Medicine, University of Perugia, Via E. Dal Pozzo, 06126 Perugia, Italy, Tel.: +39/075 5783989, Fax: +39/075 5716083, E-mail:

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http://dx.doi.org/10.1160/TH13-07-0588DOI Listing
June 2014

Stimulation of platelet nitric oxide production by nebivolol prevents thrombosis.

Arterioscler Thromb Vasc Biol 2014 Apr 20;34(4):820-9. Epub 2014 Feb 20.

From the Division of Internal and Cardiovascular Medicine, Department of Medicine, University of Perugia, Perugia, Italy (S.M., R.C., E.F., P.G.); and Department of Preclinical Development, Menarini Group, Firenze, Italy (S.E.).

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http://dx.doi.org/10.1161/ATVBAHA.114.303290DOI Listing
April 2014

C-reactive protein induces expression of matrix metalloproteinase-9: a possible link between inflammation and plaque rupture.

Int J Cardiol 2013 Sep 14;168(2):981-6. Epub 2012 Nov 14.

Department of Cardiothoracic and Respiratory Sciences, Division of Cardiology, Second University of Naples, Naples, Italy.

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http://dx.doi.org/10.1016/j.ijcard.2012.10.040DOI Listing
September 2013

In vivo platelet activation and platelet hyperreactivity in abacavir-treated HIV-infected patients.

Thromb Haemost 2013 Aug 23;110(2):349-57. Epub 2013 May 23.

Division of Internal and Cardiovascular Medicine, Department of Internal Medicine, University of Perugia, Via E. dal Pozzo, Perugia, Italy.

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http://dx.doi.org/10.1160/TH12-07-0504DOI Listing
August 2013

Nitric oxide enhances the anti-inflammatory and anti-atherogenic activity of atorvastatin in a mouse model of accelerated atherosclerosis.

Cardiovasc Res 2012 Jun 23;94(3):428-38. Epub 2012 Feb 23.

Department of Internal Medicine, Division of Internal and Cardiovascular Medicine, University of Perugia, Via E. dal Pozzo, 06126 Perugia, Italy.

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https://academic.oup.com/cardiovascres/article-lookup/doi/10
Publisher Site
http://dx.doi.org/10.1093/cvr/cvs100DOI Listing
June 2012

Contribution of matrix metalloproteinase 2 to joint destruction in group B Streptococcus-induced murine arthritis.

Arthritis Rheum 2012 Apr 31;64(4):1089-97. Epub 2011 Oct 31.

University of Perugia, Perugia, Italy.

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http://dx.doi.org/10.1002/art.33450DOI Listing
April 2012

Anti-platelet therapy: phosphodiesterase inhibitors.

Br J Clin Pharmacol 2011 Oct;72(4):634-46

Department of Internal Medicine, Section of Internal and Cardiovascular Medicine, University of Perugia, Italy.

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http://dx.doi.org/10.1111/j.1365-2125.2011.04034.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3195739PMC
October 2011

Interaction with damaged vessel wall in vivo in humans induces platelets to express CD40L resulting in endothelial activation with no effect of aspirin intake.

Am J Physiol Heart Circ Physiol 2011 Jun 4;300(6):H2072-9. Epub 2011 Mar 4.

Div. of Internal and Cardiovascular Medicine, Dept. of Internal Medicine, Univ. of Perugia, Via E. dal Pozzo, 06126 Perugia, Italy.

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http://dx.doi.org/10.1152/ajpheart.00467.2010DOI Listing
June 2011

Matrix metalloproteinases and peripheral arterial disease.

Intern Emerg Med 2010 Feb 21;5(1):13-25. Epub 2009 Jul 21.

Division of Internal and Cardiovascular Medicine, Department of Internal Medicine, University of Perugia, Via E. dal Pozzo, 06126, Perugia, Italy.

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http://dx.doi.org/10.1007/s11739-009-0283-yDOI Listing
February 2010

Loss of matrix metalloproteinase 2 in platelets reduces arterial thrombosis in vivo.

J Exp Med 2009 Oct 5;206(11):2365-79. Epub 2009 Oct 5.

Division of Internal and Cardiovascular Medicine, Department of Internal Medicine, University of Perugia, Perugia 06100, Italy.

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http://www.jem.org/lookup/doi/10.1084/jem.20090687
Publisher Site
http://dx.doi.org/10.1084/jem.20090687DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2768852PMC
October 2009

Potentiation and priming of platelet activation: a potential target for antiplatelet therapy.

Trends Pharmacol Sci 2008 Jul 6;29(7):352-60. Epub 2008 Jun 6.

Division of Internal and Cardiovascular Medicine, Department of Internal Medicine, University of Perugia, Via Enrico dal Pozzo, Perugia, Italy.

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http://dx.doi.org/10.1016/j.tips.2008.05.002DOI Listing
July 2008

Platelets release active matrix metalloproteinase-2 in vivo in humans at a site of vascular injury: lack of inhibition by aspirin.

Br J Haematol 2007 Jul;138(2):221-30

Division of Internal and Cardiovascular Medicine, Department of Internal Medicine, University of Perugia, Perugia, Italy.

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http://dx.doi.org/10.1111/j.1365-2141.2007.06632.xDOI Listing
July 2007

Endothelial dysfunction in patients with spontaneous venous thromboembolism.

Haematologica 2007 Jun;92(6):812-8

Division of Internal and Cardiovascular Medicine, Department of Internal Medicine, University of Perugia, Perugia, Italy.

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http://dx.doi.org/10.3324/haematol.10872DOI Listing
June 2007

Acute, short-term hyperglycemia enhances shear stress-induced platelet activation in patients with type II diabetes mellitus.

J Am Coll Cardiol 2003 Mar;41(6):1013-20

Division of Internal and Cardiovascular Medicine, Department of Internal Medicine, University of Perugia, via E. Dal Pozzo, snc-06126, Perugia, Italy.

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http://dx.doi.org/10.1016/s0735-1097(02)02972-8DOI Listing
March 2003