Emanuela Corsini

Emanuela Corsini

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Emanuela Corsini

Publications by authors named "Emanuela Corsini"

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Mechanistic understanding of dendritic cell activation in skin sensitization: additional evidences to support potency classification.

Toxicol Lett 2020 Apr 17;322:50-57. Epub 2020 Jan 17.

Laboratory of Toxicology, Department of Environmental and Political Sciences, Università degli Studi di Milano, Via Balzaretti 9, 20133, Milan, Italy.

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http://dx.doi.org/10.1016/j.toxlet.2020.01.014DOI Listing
April 2020

Structural features and functional activities of benzimidazoles as NOD2 antagonists.

Eur J Med Chem 2020 Jan 24;190:112089. Epub 2020 Jan 24.

Faculty of Pharmacy, University of Ljubljana, Aškerčeva 7, 1000, Ljubljana, Slovenia. Electronic address:

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http://dx.doi.org/10.1016/j.ejmech.2020.112089DOI Listing
January 2020

Study on the inflammasome nlrp3 and blimp-1/nlrp12 after keratinocyte exposure to contact allergens.

Toxicol Lett 2019 Oct 2;313:130-136. Epub 2019 Jul 2.

Department of Environmental Science and Policy, Università degli Studi di Milano, 20133 Milan, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.toxlet.2019.07.003DOI Listing
October 2019

Ultrafine Particles from Residential Biomass Combustion: A Review on Experimental Data and Toxicological Response.

Int J Mol Sci 2019 Oct 9;20(20). Epub 2019 Oct 9.

Department of Physics, Università degli Studi di Milano, and INFN-Milan, Milan 20133, Italy.

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http://dx.doi.org/10.3390/ijms20204992DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6834185PMC
October 2019

Contact allergen (PPD and DNCB)-induced keratinocyte sensitization is partly mediated through a low molecular weight hyaluronan (LMWHA)/TLR4/NF-κB signaling axis.

Toxicol Appl Pharmacol 2019 Aug 19;377:114632. Epub 2019 Jun 19.

Laboratory of Anatomy-Histology-Embryology, School of Medicine, University of Crete, Heraklion, Greece. Electronic address:

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http://dx.doi.org/10.1016/j.taap.2019.114632DOI Listing
August 2019

THP-1 Cells and Pro-inflammatory Cytokine Production: An in Vitro Tool for Functional Characterization of NOD1/NOD2 Antagonists.

Int J Mol Sci 2019 Aug 30;20(17). Epub 2019 Aug 30.

Laboratory of Toxicology, Department of Pharmacological Sciences, Università degli Studi di Milano, Via Balzaretti 9, 20133 Milan, Italy.

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http://dx.doi.org/10.3390/ijms20174265DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6747088PMC
August 2019

Cortisol-induced SRSF3 expression promotes GR splicing, RACK1 expression and breast cancer cells migration.

Pharmacol Res 2019 05 9;143:17-26. Epub 2019 Mar 9.

Department of Drugs Sciences, Università degli Studi di Pavia, Viale Taramelli 12/14, 27100, Pavia, Italy.

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http://dx.doi.org/10.1016/j.phrs.2019.03.008DOI Listing
May 2019

Evaluating Cytokines in Immunotoxicity Testing.

Methods Mol Biol 2018 ;1803:297-314

DynPort Vaccine Company LLC, Frederick, MD, USA.

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http://dx.doi.org/10.1007/978-1-4939-8549-4_18DOI Listing
March 2019

Chemical-induced contact allergy: from mechanistic understanding to risk prevention.

Arch Toxicol 2018 10 10;92(10):3031-3050. Epub 2018 Aug 10.

Department of Forensic Sciences and Toxicology, University of Crete, Heraklion, Greece.

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http://link.springer.com/10.1007/s00204-018-2283-z
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http://dx.doi.org/10.1007/s00204-018-2283-zDOI Listing
October 2018

Immunomodulators Inspired by Nature: A Review on Curcumin and Echinacea.

Molecules 2018 Oct 26;23(11). Epub 2018 Oct 26.

Department of Drug Sciences-Pharmacology Section, University of Pavia, 27100 Pavia, Italy.

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http://www.mdpi.com/1420-3049/23/11/2778
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http://dx.doi.org/10.3390/molecules23112778DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6278270PMC
October 2018

Tools to investigate and avoid drug-hypersensitivity in drug development.

Expert Opin Drug Discov 2018 05 6;13(5):425-433. Epub 2018 Feb 6.

c Inflammation, Chemokines and Immunopathology , INSERM UMR 996, Univ Paris-Sud, Université Paris-Saclay , Châtenay-Malabry , France.

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http://dx.doi.org/10.1080/17460441.2018.1437141DOI Listing
May 2018

In vitro assessment of silver nanoparticles immunotoxicity.

Food Chem Toxicol 2018 Feb 10;112:363-374. Epub 2018 Jan 10.

Laboratory of Toxicology, Department of Pharmacological and Biomolecular Sciences, Università degli Studi di Milano, 20133 Milan, Italy; Department of Environmental Science and Policy, Università degli Studi di Milano, 20133 Milan, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.fct.2017.12.023DOI Listing
February 2018

Development of an In Vitro Method to Estimate the Sensitization Induction Level of Contact Allergens.

Curr Protoc Toxicol 2018 02 21;75:20.15.1-20.15.20. Epub 2018 Feb 21.

Department of Environmental Science and Policy, Università degli Studi di Milano, Milan, Italy.

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http://dx.doi.org/10.1002/cptx.44DOI Listing
February 2018

Assessment of metal sensitizer potency with the reconstructed human epidermis IL-18 assay.

Toxicology 2018 01 25;393:62-72. Epub 2017 Oct 25.

Dental Material Sciences, Academic Centre for Dentistry Amsterdam (ACTA), University of Amsterdam and Vrije Universiteit Amsterdam, The Netherlands.

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http://dx.doi.org/10.1016/j.tox.2017.10.014DOI Listing
January 2018

Transcriptional regulation of RACK1 and modulation of its expression: Role of steroid hormones and significance in health and aging.

Cell Signal 2017 07 9;35:264-271. Epub 2017 Feb 9.

Dipartimento di Scienze del Farmaco, Università degli Studi di Pavia, Viale Taramelli 12/14, 27100 Pavia, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.cellsig.2017.02.010DOI Listing
July 2017

Role of Hormones in the Regulation of RACK1 Expression as a Signaling Checkpoint in Immunosenescence.

Int J Mol Sci 2017 Jul 6;18(7). Epub 2017 Jul 6.

Laboratory of Toxicology, Department of Environmental Science and Policy, Università degli Studi di Milano, Via Balzaretti 9, 20133 Milano, Italy.

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http://dx.doi.org/10.3390/ijms18071453DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5535944PMC
July 2017

Role of spliceosome proteins in the regulation of glucocorticoid receptor isoforms by cortisol and dehydroepiandrosterone.

Pharmacol Res 2017 Jun 31;120:180-187. Epub 2017 Mar 31.

Dipartimento di Scienze del Farmaco - Università degli Studi di Pavia, Viale Taramelli 12/14, 27100 Pavia, Italy.

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http://dx.doi.org/10.1016/j.phrs.2017.03.019DOI Listing
June 2017

The scaffold protein RACK1 is a target of endocrine disrupting chemicals (EDCs) with important implication in immunity.

Toxicol Appl Pharmacol 2017 06 13;325:37-47. Epub 2017 Apr 13.

Laboratory of Toxicology, Dipartimento di Scienze Farmacologiche e Biomolecolari, Università degli Studi di Milano, Via Balzaretti 9, 20133 Milano, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.taap.2017.04.011DOI Listing
June 2017

Editorial: Biomarkers in Drug Hypersensitivity.

Front Pharmacol 2017 7;8:348. Epub 2017 Jun 7.

Department of Pharmacology, University of ExtremaduraCáceres, Spain.

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http://dx.doi.org/10.3389/fphar.2017.00348DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5461283PMC
June 2017

Development of an in vitro method to estimate the sensitization induction level of contact allergens.

Toxicol Lett 2017 Apr 9;271:1-11. Epub 2017 Feb 9.

Laboratory of Toxicology, DiSFeB, Università degli Studi di Milano, Milan, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.toxlet.2017.01.016DOI Listing
April 2017

HA metabolism in skin homeostasis and inflammatory disease.

Food Chem Toxicol 2017 Mar 18;101:128-138. Epub 2017 Jan 18.

Laboratory of Anatomy-Histology-Embryology, School of Medicine, University of Crete, 71003 Heraklion, Greece. Electronic address:

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http://dx.doi.org/10.1016/j.fct.2017.01.012DOI Listing
March 2017

Evaluation of amniotic mesenchymal cell derivatives on cytokine production in equine alveolar macrophages: an in vitro approach to lung inflammation.

Stem Cell Res Ther 2016 09 20;7(1):137. Epub 2016 Sep 20.

Department of Health, Animal Science and Food Safety (VESPA), Università degli Studi di Milano, Via Celoria 10, 20133, Milano, Italy.

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http://dx.doi.org/10.1186/s13287-016-0398-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5028987PMC
September 2016

The role of HSP27 in RACK1-mediated PKC activation in THP-1 cells.

Immunol Res 2016 08;64(4):940-50

Department of Drug Sciences - Pharmacology, University of Pavia, Viale Taramelli 14, 27100, Pavia, Italy.

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http://dx.doi.org/10.1007/s12026-016-8802-1DOI Listing
August 2016

In vitro Models to Evaluate Drug-Induced Hypersensitivity: Potential Test Based on Activation of Dendritic Cells.

Front Pharmacol 2016 12;7:204. Epub 2016 Jul 12.

Scienze Farmacologiche e Biomolecolari, Università degli Studi di Milano Milan, Italy.

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http://dx.doi.org/10.3389/fphar.2016.00204DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4940371PMC
July 2016

Preclinical Evaluation of Tolerability of a Selective, Bacteriostatic, Locally Active Vaginal Formulation.

Curr Ther Res Clin Exp 2016;83:13-21. Epub 2016 Jul 25.

Laboratory of Toxicology, DiSFeB, Università degli Studi di Milano, Milan, Italy.

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http://dx.doi.org/10.1016/j.curtheres.2016.07.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5067097PMC
July 2016

Skin Penetrating Peptide as a Tool to Enhance the Permeation of Heparin through Human Epidermis.

Biomacromolecules 2016 Jan 14;17(1):46-55. Epub 2015 Dec 14.

Department of Pharmaceutical Sciences, Università degli Studi di Milano , Via Giuseppe Colombo, 71-20133 Milan, Italy.

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http://dx.doi.org/10.1021/acs.biomac.5b01524DOI Listing
January 2016

Optimization of the THP-1 activation assay to detect pharmaceuticals with potential to cause immune mediated drug reactions.

Toxicol In Vitro 2015 Oct 28;29(7):1339-49. Epub 2015 May 28.

Dipartimento di Scienze Farmacologiche e Biomolecolari (DiSFeB), Università degli Studi di Milano, Milan, Italy.

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http://dx.doi.org/10.1016/j.tiv.2015.04.012DOI Listing
October 2015

Assessing the carcinogenic potential of low-dose exposures to chemical mixtures in the environment: the challenge ahead.

Authors:
William H Goodson Leroy Lowe David O Carpenter Michael Gilbertson Abdul Manaf Ali Adela Lopez de Cerain Salsamendi Ahmed Lasfar Amancio Carnero Amaya Azqueta Amedeo Amedei Amelia K Charles Andrew R Collins Andrew Ward Anna C Salzberg Annamaria Colacci Ann-Karin Olsen Arthur Berg Barry J Barclay Binhua P Zhou Carmen Blanco-Aparicio Carolyn J Baglole Chenfang Dong Chiara Mondello Chia-Wen Hsu Christian C Naus Clement Yedjou Colleen S Curran Dale W Laird Daniel C Koch Danielle J Carlin Dean W Felsher Debasish Roy Dustin G Brown Edward Ratovitski Elizabeth P Ryan Emanuela Corsini Emilio Rojas Eun-Yi Moon Ezio Laconi Fabio Marongiu Fahd Al-Mulla Ferdinando Chiaradonna Firouz Darroudi Francis L Martin Frederik J Van Schooten Gary S Goldberg Gerard Wagemaker Gladys N Nangami Gloria M Calaf Graeme Williams Gregory T Wolf Gudrun Koppen Gunnar Brunborg H Kim Lyerly Harini Krishnan Hasiah Ab Hamid Hemad Yasaei Hideko Sone Hiroshi Kondoh Hosni K Salem Hsue-Yin Hsu Hyun Ho Park Igor Koturbash Isabelle R Miousse A Ivana Scovassi James E Klaunig Jan Vondráček Jayadev Raju Jesse Roman John Pierce Wise Jonathan R Whitfield Jordan Woodrick Joseph A Christopher Josiah Ochieng Juan Fernando Martinez-Leal Judith Weisz Julia Kravchenko Jun Sun Kalan R Prudhomme Kannan Badri Narayanan Karine A Cohen-Solal Kim Moorwood Laetitia Gonzalez Laura Soucek Le Jian Leandro S D'Abronzo Liang-Tzung Lin Lin Li Linda Gulliver Lisa J McCawley Lorenzo Memeo Louis Vermeulen Luc Leyns Luoping Zhang Mahara Valverde Mahin Khatami Maria Fiammetta Romano Marion Chapellier Marc A Williams Mark Wade Masoud H Manjili Matilde E Lleonart Menghang Xia Michael J Gonzalez Michalis V Karamouzis Micheline Kirsch-Volders Monica Vaccari Nancy B Kuemmerle Neetu Singh Nichola Cruickshanks Nicole Kleinstreuer Nik van Larebeke Nuzhat Ahmed Olugbemiga Ogunkua P K Krishnakumar Pankaj Vadgama Paola A Marignani Paramita M Ghosh Patricia Ostrosky-Wegman Patricia A Thompson Paul Dent Petr Heneberg Philippa Darbre Po Sing Leung Pratima Nangia-Makker Qiang Shawn Cheng R Brooks Robey Rabeah Al-Temaimi Rabindra Roy Rafaela Andrade-Vieira Ranjeet K Sinha Rekha Mehta Renza Vento Riccardo Di Fiore Richard Ponce-Cusi Rita Dornetshuber-Fleiss Rita Nahta Robert C Castellino Roberta Palorini Roslida Abd Hamid Sabine A S Langie Sakina E Eltom Samira A Brooks Sandra Ryeom Sandra S Wise Sarah N Bay Shelley A Harris Silvana Papagerakis Simona Romano Sofia Pavanello Staffan Eriksson Stefano Forte Stephanie C Casey Sudjit Luanpitpong Tae-Jin Lee Takemi Otsuki Tao Chen Thierry Massfelder Thomas Sanderson Tiziana Guarnieri Tove Hultman Valérian Dormoy Valerie Odero-Marah Venkata Sabbisetti Veronique Maguer-Satta W Kimryn Rathmell Wilhelm Engström William K Decker William H Bisson Yon Rojanasakul Yunus Luqmani Zhenbang Chen Zhiwei Hu

Carcinogenesis 2015 Jun;36 Suppl 1:S254-96

Department of Surgery, The Ohio State University College of Medicine, The James Comprehensive Cancer Center, Columbus, OH 43210, USA.

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http://carcin.oxfordjournals.org/content/36/Suppl_1/S254.ful
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http://carcin.oxfordjournals.org/content/36/Suppl_1/S254.ful
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http://www.ilcambiamento.it/files/carcinogenesi.pdf
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http://www.carcin.oxfordjournals.org/lookup/doi/10.1093/carc
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http://dx.doi.org/10.1093/carcin/bgv039DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4480130PMC
June 2015

Hyaluronan regulates chemical allergen-induced IL-18 production in human keratinocytes.

Toxicol Lett 2015 Jan 1;232(1):89-97. Epub 2014 Oct 1.

Laboratory of Toxicology, DiSFeB, Università degli Studi di Milano, Italy.

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http://dx.doi.org/10.1016/j.toxlet.2014.09.026DOI Listing
January 2015

Role of ROS and HMGB1 in contact allergen-induced IL-18 production in human keratinocytes.

J Invest Dermatol 2014 Nov 29;134(11):2719-2727. Epub 2014 Apr 29.

Laboratory of Toxicology, DiSFeB, Università degli Studi di Milano, Milan, Italy.

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http://dx.doi.org/10.1038/jid.2014.203DOI Listing
November 2014

Perfluorinated compounds: emerging POPs with potential immunotoxicity.

Toxicol Lett 2014 Oct 3;230(2):263-70. Epub 2014 Feb 3.

Department of Pharmacology and Toxicology, Brody School of Medicine, East Carolina University, Greenville, NC, USA.

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http://dx.doi.org/10.1016/j.toxlet.2014.01.038DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4439925PMC
October 2014

Immunotoxicology: challenges in the 21st century and in vitro opportunities.

ALTEX 2013 ;30(4):411-26

Johns Hopkins University, Bloomberg School of Public Health, CAAT, Baltimore, USA and University of Konstanz, CAAT-Europe, Germany.

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http://dx.doi.org/10.14573/altex.2013.4.411DOI Listing
June 2014

Corticosteroids modulate the expression of the PKC-anchoring protein RACK-1 and cytokine release in THP-1 cells.

Pharmacol Res 2014 Mar 22;81:10-6. Epub 2014 Jan 22.

Department of Drug Sciences - Pharmacology, University of Pavia, Pavia, Italy.

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http://dx.doi.org/10.1016/j.phrs.2014.01.002DOI Listing
March 2014

NCTC 2544 and IL-18 production: a tool for the in vitro identification of photoallergens.

Toxicol In Vitro 2014 Feb 28;28(1):13-7. Epub 2013 Jun 28.

Laboratory of Toxicology, Department of Pharmacological Sciences, Università degli Studi di Milano, Milan, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.tiv.2013.06.008DOI Listing
February 2014

Role of PKC-β in chemical allergen-induced CD86 expression and IL-8 release in THP-1 cells.

Arch Toxicol 2014 Feb 18;88(2):415-24. Epub 2013 Oct 18.

Laboratory of Toxicology, Dipartimento di Scienze Farmacologiche e Biomolecolari (DiSFeB), Università degli Studi di Milano, Via G. Balzaretti 9, 20133, Milan, Italy,

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http://dx.doi.org/10.1007/s00204-013-1144-zDOI Listing
February 2014

Approaches and considerations for the assessment of immunotoxicity for environmental chemicals: a workshop summary.

Regul Toxicol Pharmacol 2014 Feb 23;68(1):96-107. Epub 2013 Nov 23.

Office of Pesticides Programs, US Environmental Protection Agency, Washington, DC, United States.

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http://dx.doi.org/10.1016/j.yrtph.2013.11.012DOI Listing
February 2014

Early maternal deprivation immunologically primes hippocampal synapses by redistributing interleukin-1 receptor type I in a sex dependent manner.

Brain Behav Immun 2014 Jan 21;35:135-43. Epub 2013 Sep 21.

Departamento de Fisiología (Fisiología Animal II), Facultad de Biología, Universidad Complutense de Madrid, Madrid, Spain; Instituto de Investigación Sanitaria del Hospital Clínico San Carlos (IdISSC), Madrid, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.bbi.2013.09.008DOI Listing
January 2014

Comparison of wood smoke PM2.5 obtained from the combustion of FIR and beech pellets on inflammation and DNA damage in A549 and THP-1 human cell lines.

Arch Toxicol 2013 Dec 14;87(12):2187-99. Epub 2013 May 14.

Laboratory of Toxicology, Dipartimento di Scienze Farmacologiche e Biomolecolari (DiSFeB), Università degli Studi di Milano, Via Balzaretti 9, 20133, Milan, Italy,

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http://dx.doi.org/10.1007/s00204-013-1071-zDOI Listing
December 2013

Role of oxidative stress in chemical allergens induced skin cells activation.

Food Chem Toxicol 2013 Nov 27;61:74-81. Epub 2013 Feb 27.

Laboratory of Toxicology, DiSFeB, Università degli Studi di Milano, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.fct.2013.02.038DOI Listing
November 2013

ROS-major mediators of extracellular matrix remodeling during tumor progression.

Food Chem Toxicol 2013 Nov 17;61:178-86. Epub 2013 Jun 17.

Department of Histology-Embryology, School of Medicine, University of Crete, Heraklion, Greece. Electronic address:

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http://dx.doi.org/10.1016/j.fct.2013.06.013DOI Listing
November 2013

An epidermal equivalent assay for identification and ranking potency of contact sensitizers.

Toxicol Appl Pharmacol 2013 Oct 19;272(2):529-41. Epub 2013 Jul 19.

Department of Dermatology, VU University Medical Centre, Dept of Oral Cell Biology, ACTA, Amsterdam, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.taap.2013.07.003DOI Listing
October 2013

Dendritic cell migration assay: a potential prediction model for identification of contact allergens.

Toxicol In Vitro 2013 Apr 7;27(3):1170-9. Epub 2012 Jun 7.

Department of Dermatology, VU University Medical Centre, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1016/j.tiv.2012.05.016DOI Listing
April 2013

NCTC 2544 and IL-18 production: a tool for the identification of contact allergens.

Toxicol In Vitro 2013 Apr 9;27(3):1127-34. Epub 2012 Oct 9.

Laboratory of Toxicology, Department of Pharmacological Sciences, Università degli Studi di Milano, Milan, Italy.

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http://dx.doi.org/10.1016/j.tiv.2012.05.018DOI Listing
April 2013

Establishment of an in vitro photoallergy test using NCTC2544 cells and IL-18 production.

Toxicol In Vitro 2013 Feb 5;27(1):103-10. Epub 2012 Oct 5.

Laboratory of Toxicology, Dipartimento di Scienze Farmacologiche e Biomolecolari, Università degli Studi di Milano, Milan, Italy.

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http://dx.doi.org/10.1016/j.tiv.2012.09.017DOI Listing
February 2013

The NCTC 2544 IL-18 assay for the in vitro identification of contact allergens.

Curr Protoc Toxicol 2012 Nov;Chapter 20:Unit 20.8

Department of Pharmacological Sciences, Università degli Studi di Milano, Milan, Italy.

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http://dx.doi.org/10.1002/0471140856.tx2008s54DOI Listing
November 2012

Immune changes in animal breeders: a pilot study conducted in northern Italy.

Ann Agric Environ Med 2012 ;19(2):221-5

Department of Occupational and Environmental Health, University of Milan, International Centre for Rural Health, University Hospital San Paolo, Milan, Italy.

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October 2012

Alterations in regulatory T-cells: rediscovered pathways in immunotoxicology.

J Immunotoxicol 2011 Oct-Dec;8(4):251-7. Epub 2011 Aug 17.

Laboratory of Toxicology, Department of Pharmacological Sciences, Università degli Studi di Milano, Italy.

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http://dx.doi.org/10.3109/1547691X.2011.598885DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3448276PMC
March 2012

Isoeugenol destabilizes IL-8 mRNA expression in THP-1 cells through induction of the negative regulator of mRNA stability tristetraprolin.

Arch Toxicol 2012 Feb 4;86(2):239-48. Epub 2011 Oct 4.

Department of Pharmacological Sciences, Faculty of Pharmacy, Laboratory of Toxicology, Università degli Studi di Milano, Via Balzaretti 9, 20133, Milan, Italy.

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http://dx.doi.org/10.1007/s00204-011-0758-2DOI Listing
February 2012

In vitro characterization of the immunotoxic potential of several perfluorinated compounds (PFCs).

Toxicol Appl Pharmacol 2012 Jan 18;258(2):248-55. Epub 2011 Nov 18.

Laboratory of Toxicology, Department of Pharmacological Sciences, Università degli Studi di Milano, Via Balzaretti 9, 20133 Milano, Italy.

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http://dx.doi.org/10.1016/j.taap.2011.11.004DOI Listing
January 2012

Opposing effects of cortisol and dehydroepiandrosterone on the expression of the receptor for Activated C Kinase 1: implications in immunosenescence.

Exp Gerontol 2011 Nov 27;46(11):877-83. Epub 2011 Jul 27.

Department of Drug Sciences-Pharmacology Section, Center of Excellence in Applied Biology, University of Pavia, Viale Taramelli 14, Pavia, Italy.

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http://dx.doi.org/10.1016/j.exger.2011.07.007DOI Listing
November 2011

Design, synthesis and biological evaluation of novel desmuramyldipeptide analogs.

Eur J Med Chem 2011 Sep 27;46(9):3762-77. Epub 2011 May 27.

Faculty of Pharmacy, University of Ljubljana, Aškerčeva 7, SI-1000 Ljubljana, Slovenia.

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http://dx.doi.org/10.1016/j.ejmech.2011.05.042DOI Listing
September 2011

Present and future of in vitro immunotoxicology in drug development.

J Immunotoxicol 2010 Oct-Dec;7(4):255-67. Epub 2010 Aug 24.

Laboratory of Toxicology, Department of Pharmacological Sciences, Faculty of Pharmacy, University of Milan, Milan, Italy.

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http://dx.doi.org/10.3109/1547691X.2010.509848DOI Listing
June 2011

In vitro evaluation of the immunotoxic potential of perfluorinated compounds (PFCs).

Toxicol Appl Pharmacol 2011 Jan 12;250(2):108-16. Epub 2010 Nov 12.

Laboratory of Toxicology, Department of Pharmacological Sciences, Università degli Studi di Milano, Via Balzaretti 9, 20133 Milano, Italy.

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http://dx.doi.org/10.1016/j.taap.2010.11.004DOI Listing
January 2011

Enterodiol and enterolactone modulate the immune response by acting on nuclear factor-kappaB (NF-kappaB) signaling.

J Agric Food Chem 2010 Jun;58(11):6678-84

Laboratory of Toxicology, Department of Pharmacological Sciences, Università degli Studi di Milano, Via Balzaretti 9, 20133 Milano, Italy.

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http://dx.doi.org/10.1021/jf100471nDOI Listing
June 2010

Evaluating cytokines in immunotoxicity testing.

Methods Mol Biol 2010 ;598:283-302

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http://dx.doi.org/10.1007/978-1-60761-401-2_20DOI Listing
February 2010

Immunotoxicology: opportunities for non-animal test development.

Altern Lab Anim 2009 Sep;37(4):387-97

Laboratory of Toxicology, Department of Pharmacological Sciences, Faculty of Pharmacy, University of Milan, Milan, Italy.

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http://dx.doi.org/10.1177/026119290903700409DOI Listing
September 2009

Use of IL-18 production in a human keratinocyte cell line to discriminate contact sensitizers from irritants and low molecular weight respiratory allergens.

Toxicol In Vitro 2009 Aug 4;23(5):789-96. Epub 2009 May 4.

Department of Pharmacological Sciences, Faculty of Pharmacy, Laboratory of Toxicology, University of Milan, Milan, Italy.

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http://dx.doi.org/10.1016/j.tiv.2009.04.005DOI Listing
August 2009

Functional mapping of the promoter region of the GNB2L1 human gene coding for RACK1 scaffold protein.

Gene 2009 Feb 21;430(1-2):17-29. Epub 2008 Oct 21.

University of Pavia, Department of Experimental and Applied Pharmacology, Centre of Excellence in Applied Biology, Viale Taramelli 14, 27100 Pavia, Italy.

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http://dx.doi.org/10.1016/j.gene.2008.10.005DOI Listing
February 2009

Dithiocarbamate propineb induces acetylcholine release through cytoskeletal actin depolymerization in PC12 cells.

Toxicol Lett 2008 Nov 4;182(1-3):63-8. Epub 2008 Sep 4.

Department of Pharmacological Sciences, Laboratory of Toxicology, University of Milan, Italy.

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http://dx.doi.org/10.1016/j.toxlet.2008.08.016DOI Listing
November 2008

Role of p38 MAPK in the selective release of IL-8 induced by chemical allergen in naive THp-1 cells.

Toxicol In Vitro 2008 Mar;22(2):386-95

Departament de Fisiologia, Facultat de Farmàcia, Universitat de Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.1016/j.tiv.2007.10.005DOI Listing
March 2008

Role of SP-1 in SDS-induced adipose differentiation related protein synthesis in human keratinocytes.

Gene Regul Syst Bio 2007 Oct 4;1:207-15. Epub 2007 Oct 4.

Laboratory of Toxicology, Department of Pharmacological Sciences, University of Milan, Via Balzaretti 9, 20133 Milan, Italy.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2759128PMC
October 2007

Immunomodulatory effects of the herbicide propanil on cytokine production in humans: In vivo and in vitro exposure.

Toxicol Appl Pharmacol 2007 Jul 21;222(2):202-10. Epub 2007 May 21.

Laboratory of Toxicology, Department of Pharmacological Sciences, University of Milan, Via Balzaretti 9, 20133 Milan, Italy.

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http://dx.doi.org/10.1016/j.taap.2007.04.017DOI Listing
July 2007

Factors governing susceptibility to chemical allergy.

Toxicol Lett 2007 Feb 16;168(3):255-9. Epub 2006 Nov 16.

Laboratory of Toxicology, Institute of Pharmacological Sciences, University of Milan, Via Balzaretti 9, 20133 Milan, Italy.

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http://dx.doi.org/10.1016/j.toxlet.2006.09.015DOI Listing
February 2007

Interleukin-1 beta released by gp120 drives neural death through tyrosine phosphorylation and trafficking of NMDA receptors.

J Biol Chem 2006 Oct 3;281(40):30212-22. Epub 2006 Aug 3.

Laboratory of Toxicology and Center of Excellence on Neurodegenerative Diseases, Department of Pharmacological Sciences, University of Milan, 20133 Milan, Italy.

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http://www.jbc.org/lookup/doi/10.1074/jbc.M602156200
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http://dx.doi.org/10.1074/jbc.M602156200DOI Listing
October 2006

High interleukin-10 production is associated with low antibody response to influenza vaccination in the elderly.

J Leukoc Biol 2006 Aug 17;80(2):376-82. Epub 2006 May 17.

Laboratory of Toxicology, Department of Pharmacological Sciences, Faculty of Pharmacy, Milan, Italy.

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http://doi.wiley.com/10.1189/jlb.0306190
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http://dx.doi.org/10.1189/jlb.0306190DOI Listing
August 2006

Molecular mechanisms underlying mancozeb-induced inhibition of TNF-alpha production.

Toxicol Appl Pharmacol 2006 Apr 19;212(2):89-98. Epub 2005 Aug 19.

Laboratory of Toxicology, Department of Pharmacological Sciences, University of Milan, Via Balzaretti 9, 20133 Milan, Italy.

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http://dx.doi.org/10.1016/j.taap.2005.07.002DOI Listing
April 2006

RACK-1 expression and cytokine production in leukocytes obtained from AD patients.

Aging Clin Exp Res 2006 Apr;18(2):153-7

Department of Experimental and Applied Pharmacology, University of Pavia, Italy.

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http://dx.doi.org/10.1007/bf03327432DOI Listing
April 2006

Immunomodulatory effects of the fungicide Mancozeb in agricultural workers.

Toxicol Appl Pharmacol 2005 Oct;208(2):178-85

Laboratory of Toxicology, Department of Pharmacological Sciences, University of Milan, Via Balzaretti 9, 20133 Milan, Italy.

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http://dx.doi.org/10.1016/j.taap.2005.02.011DOI Listing
October 2005

Erythropoietin: a novel neuroprotective cytokine.

Neurotoxicology 2005 Oct 31;26(5):923-8. Epub 2005 May 31.

Laboratory of Toxicology and Centre of Excellence on Neurodegenerative Diseases, Department of Pharmacological Sciences, University of Milan, Via Balzaretti 9, 20133 Milan, Italy.

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http://dx.doi.org/10.1016/j.neuro.2005.01.016DOI Listing
October 2005

Erythropoietin protects primary hippocampal neurons increasing the expression of brain-derived neurotrophic factor.

J Neurochem 2005 Apr;93(2):412-21

Laboratory of Toxicology and Centre of Excellence on Neurodegenerative Diseases, Department of Pharmacological Sciences, University of Milan, Milan, Italy.

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http://dx.doi.org/10.1111/j.1471-4159.2005.03033.xDOI Listing
April 2005

Age-related decline in RACK-1 expression in human leukocytes is correlated to plasma levels of dehydroepiandrosterone.

J Leukoc Biol 2005 Feb 17;77(2):247-56. Epub 2004 Nov 17.

Laboratories of Toxicology, Department of Pharmacological Sciences, University of Milan, Via Balzaretti 9, 20133 Milan, Italy.

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http://dx.doi.org/10.1189/jlb.0504268DOI Listing
February 2005

New insights into the mechanisms involved in renal proximal tubular damage induced in vitro by ochratoxin A.

J Biochem Mol Toxicol 2004 ;18(1):43-9

ECVAM, Institute for Health & Consumer Protection, Via Fermi 1, 21020 Ispra (Va), Italy.

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http://dx.doi.org/10.1002/jbt.20006DOI Listing
October 2004

Cytokines role in neurodegenerative events.

Toxicol Lett 2004 Apr;149(1-3):85-9

Laboratory of Toxicology and Center of Excellence on Neurodegenerative Diseases, Department of Pharmacological Sciences, University of Milan, Via Balzaretti 9, 20133 Milan, Italy.

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http://dx.doi.org/10.1016/j.toxlet.2003.12.022DOI Listing
April 2004

Resistance to acute silicosis in senescent rats: role of alveolar macrophages.

Chem Res Toxicol 2003 Dec;16(12):1520-7

Laboratory of Toxicology, Department of Pharmacological Sciences, University of Milan, Via Balzaretti 9, 20133 Milan, Italy.

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http://dx.doi.org/10.1021/tx034139+DOI Listing
December 2003

Dehydroepiandrosterone (DHEA) and the aging brain: flipping a coin in the "fountain of youth".

CNS Drug Rev 2003 ;9(1):21-40

Department of Experimental and Applied Pharmacology, University of Pavia, Italy.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6741703PMC
http://dx.doi.org/10.1111/j.1527-3458.2003.tb00242.xDOI Listing
May 2003

The anti-inflammatory activity of estrogen in glial cells is regulated by the PKC-anchoring protein RACK-1.

J Neurochem 2002 Dec;83(5):1180-7

Centre of Excellence on Neurodegenerative Diseases and Laboratory of Toxicology, Department of Pharmacological Sciences, University of Milan, Milan, Italy.

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http://dx.doi.org/10.1046/j.1471-4159.2002.01235.xDOI Listing
December 2002