Publications Authored by Emanuel Schwarz

Common brain disorders are associated with heritable patterns of apparent aging of the brain.

Authors:

Tobias Kaufmann Dennis van der Meer Nhat Trung Doan Emanuel Schwarz Martina J Lund Ingrid Agartz Dag Alnæs Deanna M Barch Ramona Baur-Streubel Alessandro Bertolino Francesco Bettella Mona K Beyer Erlend Bøen Stefan Borgwardt Christine L Brandt Jan Buitelaar Elisabeth G Celius Simon Cervenka Annette Conzelmann Aldo Córdova-Palomera Anders M Dale Dominique J F de Quervain PasqualeDi Carlo Srdjan Djurovic Erlend S Dørum Sarah Eisenacher Torbjørn Elvsåshagen Thomas Espeseth Helena Fatouros-Bergman Lena Flyckt Barbara Franke Oleksandr Frei Beathe Haatveit Asta K Håberg Hanne F Harbo Catharina A Hartman Dirk Heslenfeld Pieter J Hoekstra Einar A Høgestøl Terry L Jernigan Rune Jonassen Erik G Jönsson Peter Kirsch Iwona Kłoszewska Knut K Kolskår Nils Inge Landrø StephanieLe Hellard Klaus-Peter Lesch Simon Lovestone Arvid Lundervold Astri J Lundervold Luigi A Maglanoc Ulrik F Malt Patrizia Mecocci Ingrid Melle Andreas Meyer-Lindenberg Torgeir Moberget Linn B Norbom Jan Egil Nordvik Lars Nyberg Jaap Oosterlaan Marco Papalino Andreas Papassotiropoulos Paul Pauli Giulio Pergola Karin Persson Geneviève Richard Jaroslav Rokicki Anne-Marthe Sanders Geir Selbæk Alexey A Shadrin Olav B Smeland Hilkka Soininen Piotr Sowa Vidar M Steen Magda Tsolaki Kristine M Ulrichsen Bruno Vellas Lei Wang Eric Westman Georg C Ziegler Mathias Zink Ole A Andreassen Lars T Westlye

Nat Neurosci 2019 10 24;22(10):1617-1623. Epub 2019 Sep 24.

NORMENT, Division of Mental Health and Addiction Oslo University Hospital & Institute of Clinical Medicine, University of Oslo, Oslo, Norway.

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http://dx.doi.org/10.1038/s41593-019-0471-7	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6823048	PMC

October 2019

Genome-wide Association Studies in Ancestrally Diverse Populations: Opportunities, Methods, Pitfalls, and Recommendations.

Cell 2019 Oct 10;179(3):589-603. Epub 2019 Oct 10.

Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA 94305, USA.

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http://dx.doi.org/10.1016/j.cell.2019.08.051	DOI Listing

October 2019

Neural correlates of individual differences in affective benefit of real-life urban green space exposure.

Authors:

Heike Tost Markus Reichert Urs Braun Iris Reinhard Robin Peters Sven Lautenbach Andreas Hoell Emanuel Schwarz Ulrich Ebner-Priemer Alexander Zipf Andreas Meyer-Lindenberg

Nat Neurosci 2019 09 29;22(9):1389-1393. Epub 2019 Jul 29.

Department of Psychiatry and Psychotherapy, Central Institute of Mental Health, University of Heidelberg, Medical Faculty Mannheim, Mannheim, Baden-Wuerttemberg, Germany.

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http://dx.doi.org/10.1038/s41593-019-0451-y	DOI Listing

September 2019

Computational Approaches for Identification of Pleiotropic Biomarker Profiles in Psychiatry.

Authors:

Han Cao Emanuel Schwarz

Adv Exp Med Biol 2019 ;1134:111-128

Department of Psychiatry and Psychotherapy, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.

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http://dx.doi.org/10.1007/978-3-030-12668-1_6	DOI Listing

August 2019

Brain Heterogeneity in Schizophrenia and Its Association With Polygenic Risk.

JAMA Psychiatry 2019 Jul;76(7):739-748

Norwegian Centre for Mental Disorders Research, KG Jebsen Centre for Psychosis Research, Division of Mental Health and Addiction, Oslo University Hospital and Institute of Clinical Medicine, University of Oslo, Norway.

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http://archpsyc.jamanetwork.com/article.aspx?doi=10.1001/jam	Publisher Site
http://dx.doi.org/10.1001/jamapsychiatry.2019.0257	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6583664	PMC

July 2019

RMTL: an R library for multi-task learning.

Authors:

Han Cao Jiayu Zhou Emanuel Schwarz

Bioinformatics 2019 May;35(10):1797-1798

Department of Psychiatry and Psychotherapy, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.

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https://academic.oup.com/bioinformatics/advance-article/doi/	Publisher Site
http://dx.doi.org/10.1093/bioinformatics/bty831	DOI Listing

May 2019

Gimpute: an efficient genetic data imputation pipeline.

Authors:

Junfang Chen Dietmar Lippold Josef Frank William Rayner Andreas Meyer-Lindenberg Emanuel Schwarz

Bioinformatics 2019 Apr;35(8):1433-1435

Department of Psychiatry and Psychotherapy, Heidelberg University, Mannheim, Germany.

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http://dx.doi.org/10.1093/bioinformatics/bty814	DOI Listing

April 2019

Reproducible grey matter patterns index a multivariate, global alteration of brain structure in schizophrenia and bipolar disorder.

Transl Psychiatry 2019 01 17;9(1):12. Epub 2019 Jan 17.

Department of Psychiatry and Psychotherapy, Central Institute of Mental Health, Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany.

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http://dx.doi.org/10.1038/s41398-018-0225-4	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6341112	PMC

January 2019

Resting-state brain network features associated with short-term skill learning ability in humans and the influence of -methyl-d-aspartate receptor antagonism.

Authors:

Zhenxiang Zang Lena S Geiger Urs Braun Hengyi Cao Maria Zangl Axel Schäfer Carolin Moessnang Matthias Ruf Janine Reis Janina I Schweiger Luanna Dixson Alexander Moscicki Emanuel Schwarz Andreas Meyer-Lindenberg Heike Tost

Netw Neurosci 2018 1;2(4):464-480. Epub 2018 Oct 1.

Department of Psychiatry and Psychotherapy, Research Group System Neuroscience in Psychiatry, Central Institute of Mental Health, University of Heidelberg, Medical Faculty Mannheim, Mannheim, Germany.

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https://www.mitpressjournals.org/doi/abs/10.1162/netn_a_0004	Publisher Site
http://dx.doi.org/10.1162/netn_a_00045	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6175691	PMC

October 2018

Comparative Evaluation of Machine Learning Strategies for Analyzing Big Data in Psychiatry.

Authors:

Han Cao Andreas Meyer-Lindenberg Emanuel Schwarz

Int J Mol Sci 2018 Oct 29;19(11). Epub 2018 Oct 29.

Department of Psychiatry and Psychotherapy, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, 68159 Mannheim, Germany.

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http://dx.doi.org/10.3390/ijms19113387	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274760	PMC

October 2018

Male increase in brain gene expression variability is linked to genetic risk for schizophrenia.

Authors:

Junfang Chen Han Cao Andreas Meyer-Lindenberg Emanuel Schwarz

Transl Psychiatry 2018 08 1;8(1):140. Epub 2018 Aug 1.

Medical Faculty Mannheim, Department of Psychiatry and Psychotherapy, Central Institute of Mental Health, Heidelberg University, Mannheim, Germany.

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http://dx.doi.org/10.1038/s41398-018-0200-0	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6070530	PMC

August 2018

A gene-based review of RGS4 as a putative risk gene for psychiatric illness.

Authors:

Emanuel Schwarz

Am J Med Genet B Neuropsychiatr Genet 2018 03 24;177(2):267-273. Epub 2017 May 24.

Medical Faculty Mannheim, Department of Psychiatry and Psychotherapy, Central Institute of Mental Health, Heidelberg University, Mannheim, Germany.

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http://dx.doi.org/10.1002/ajmg.b.32547	DOI Listing

March 2018

Identification and Clinical Translation of Biomarker Signatures: Statistical Considerations.

Authors:

Emanuel Schwarz

Methods Mol Biol 2017 ;1546:103-114

Department of Psychiatry and Psychotherapy, Medical Faculty Mannheim, Central Institute of Mental Health, Heidelberg University, Mannheim, Germany.

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http://dx.doi.org/10.1007/978-1-4939-6730-8_6	DOI Listing

February 2018

Opportunities and Challenges of Multiplex Assays: A Machine Learning Perspective.

Authors:

Junfang Chen Emanuel Schwarz

Methods Mol Biol 2017 ;1546:115-122

Department of Psychiatry and Psychotherapy, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, J 5, Mannheim, 68159, Germany.

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http://dx.doi.org/10.1007/978-1-4939-6730-8_7	DOI Listing

February 2018

Analysis of microbiota in first episode psychosis identifies preliminary associations with symptom severity and treatment response.

Authors:

Emanuel Schwarz Johanna Maukonen Tiina Hyytiäinen Tuula Kieseppä Matej Orešič Sarven Sabunciyan Outi Mantere Maria Saarela Robert Yolken Jaana Suvisaari

Schizophr Res 2018 02 22;192:398-403. Epub 2017 Apr 22.

National Institute for Health and Welfare (THL), Helsinki, Finland.

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http://dx.doi.org/10.1016/j.schres.2017.04.017	DOI Listing

February 2018

A polygenic score for schizophrenia predicts glycemic control.

Authors:

Han Cao Junfang Chen Andreas Meyer-Lindenberg Emanuel Schwarz

Transl Psychiatry 2017 12 18;7(12):1295. Epub 2017 Dec 18.

Department of Psychiatry and Psychotherapy, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.

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http://dx.doi.org/10.1038/s41398-017-0044-z	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5802590	PMC

December 2017

Association of anandamide with altered binocular depth inversion illusion in schizophrenia.

Authors:

Anne R Reuter J Malte Bumb Juliane K Mueller Cathrin Rohleder Franziska Pahlisch Franziska Hanke Elisabeth Arens F Markus Leweke Dagmar Koethe Emanuel Schwarz

World J Biol Psychiatry 2017 09 11;18(6):483-488. Epub 2016 Nov 11.

a Department of Psychiatry and Psychotherapy , Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University , Mannheim , Germany.

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http://dx.doi.org/10.1080/15622975.2016.1246750	DOI Listing

September 2017

The Utility of Multiplex Assays for Identification of Proteomic Signatures in Psychiatry.

Authors:

Junfang Chen Paul C Guest Emanuel Schwarz

Adv Exp Med Biol 2017 ;974:131-138

Department of Psychiatry and Psychotherapy, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.

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http://dx.doi.org/10.1007/978-3-319-52479-5_8	DOI Listing

September 2017

Multiplex Immunoassay Profiling of Serum in Psychiatric Disorders.

Authors:

Laurie Stephen Emanuel Schwarz Paul C Guest

Adv Exp Med Biol 2017 ;974:149-156

Laboratory of Neuroproteomics, Department of Biochemistry and Tissue Biology, Institute of Biology, University of Campinas (UNICAMP), Rua Monteiro Lobato 255 F/01, Cidade Universitária ZeferinoVaz, 13083-862, Campinas, Brazil.

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http://dx.doi.org/10.1007/978-3-319-52479-5_10	DOI Listing

September 2017

Protein Interaction Networks Link Schizophrenia Risk Loci to Synaptic Function.

Authors:

Emanuel Schwarz Rauf Izmailov Pietro Liò Andreas Meyer-Lindenberg

Schizophr Bull 2016 11 7;42(6):1334-1342. Epub 2016 Apr 7.

Department of Psychiatry and Psychotherapy, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5049524	PMC
http://dx.doi.org/10.1093/schbul/sbw035	DOI Listing

November 2016

Dynamic brain network reconfiguration as a potential schizophrenia genetic risk mechanism modulated by NMDA receptor function.

Authors:

Urs Braun Axel Schäfer Danielle S Bassett Franziska Rausch Janina I Schweiger Edda Bilek Susanne Erk Nina Romanczuk-Seiferth Oliver Grimm Lena S Geiger Leila Haddad Kristina Otto Sebastian Mohnke Andreas Heinz Mathias Zink Henrik Walter Emanuel Schwarz Andreas Meyer-Lindenberg Heike Tost

Proc Natl Acad Sci U S A 2016 11 17;113(44):12568-12573. Epub 2016 Oct 17.

Department of Psychiatry and Psychotherapy, Central Institute of Mental Health, Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany;

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http://dx.doi.org/10.1073/pnas.1608819113	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5098640	PMC

November 2016

The association of pineal gland volume and body mass in obese and normal weight individuals: a pilot study.

Authors:

Martin Grosshans Christian Vollmert Sabine Vollstaedt-Klein Ingo Nolte Emanuel Schwarz Xenija Wagner Markus Leweke Jochen Mutschler Falk Kiefer Jan Malte Bumb

Psychiatr Danub 2016 Sep;28(3):220-224

Department of Addictive Behaviour and Addiction Medicine, Central Institute of Mental Health, Medical Faculty Mannheim/University of Heidelberg, Mannheim, Germany.

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September 2016

Identifying multimodal signatures associated with symptom clusters: the example of the IMAGEMEND project.

Authors:

Sophia Frangou Emanuel Schwarz Andreas Meyer-Lindenberg

World Psychiatry 2016 Jun;15(2):179-80

Central Institute of Mental Health, Mannheim, Germany.

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http://dx.doi.org/10.1002/wps.20334	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4911783	PMC

June 2016

Genetic influences on schizophrenia and subcortical brain volumes: large-scale proof of concept.

Nat Neurosci 2016 Mar 1;19(3):420-431. Epub 2016 Feb 1.

Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.

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http://dx.doi.org/10.1038/nn.4228	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4852730	PMC

March 2016

Pretreatment levels of the fatty acid handling proteins H-FABP and CD36 predict response to olanzapine in recent-onset schizophrenia patients.

Authors:

Jakub Tomasik Emanuel Schwarz Santiago G Lago Matthias Rothermundt F Markus Leweke Nico J M van Beveren Paul C Guest Hassan Rahmoune Johann Steiner Sabine Bahn

Brain Behav Immun 2016 Feb 2;52:178-186. Epub 2015 Nov 2.

Department of Chemical Engineering and Biotechnology, University of Cambridge, Cambridge, UK; Department of Neuroscience, Erasmus Medical Centre, Rotterdam, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.bbi.2015.10.019	DOI Listing

February 2016

Working memory genetics in schizophrenia and related disorders: An RDoC perspective.

Authors:

Emanuel Schwarz Heike Tost Andreas Meyer-Lindenberg

Am J Med Genet B Neuropsychiatr Genet 2016 Jan 14;171B(1):121-31. Epub 2015 Sep 14.

Department of Psychiatry and Psychotherapy, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.

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http://doi.wiley.com/10.1002/ajmg.b.32353	Publisher Site
http://dx.doi.org/10.1002/ajmg.b.32353	DOI Listing

January 2016

Neural Correlates of the Cortisol Awakening Response in Humans.

Authors:

Andreas Boehringer Heike Tost Leila Haddad Florian Lederbogen Stefan Wüst Emanuel Schwarz Andreas Meyer-Lindenberg

Neuropsychopharmacology 2015 Aug 17;40(9):2278-85. Epub 2015 Mar 17.

Central Institute for Mental Health, University of Heidelberg/Medical Faculty Mannheim, J5, Mannheim, Germany.

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http://dx.doi.org/10.1038/npp.2015.77	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4613622	PMC

August 2015

IgG dynamics of dietary antigens point to cerebrospinal fluid barrier or flow dysfunction in first-episode schizophrenia.

Authors:

Emily G Severance Kristin L Gressitt Armin Alaedini Cathrin Rohleder Frank Enning J Malte Bumb Juliane K Müller Emanuel Schwarz Robert H Yolken F Markus Leweke

Brain Behav Immun 2015 Feb 20;44:148-58. Epub 2014 Sep 20.

Department of Psychiatry and Psychotherapy, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.

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http://dx.doi.org/10.1016/j.bbi.2014.09.009	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4275312	PMC

February 2015

Investigation of molecular serum profiles associated with predisposition to antipsychotic-induced weight gain.

Authors:

Emanuel Schwarz Johann Steiner Paul C Guest Bernhard Bogerts Sabine Bahn

World J Biol Psychiatry 2015 Jan 3;16(1):22-30. Epub 2013 Sep 3.

Department of Chemical Engineering and Biotechnology, University of Cambridge , Cambridge , UK.

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http://dx.doi.org/10.3109/15622975.2013.817685	DOI Listing

January 2015

Oleoylethanolamide and human neural responses to food stimuli in obesity.

Authors:

Martin Grosshans Emanuel Schwarz Jan Malte Bumb Carola Schaefer Cathrin Rohleder Christian Vollmert Sabine Vollstädt-Klein Heike Tost Andreas Meyer-Lindenberg Falk Kiefer F Markus Leweke

JAMA Psychiatry 2014 Nov;71(11):1254-61

Department of Psychiatry and Psychotherapy, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.

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http://dx.doi.org/10.1001/jamapsychiatry.2014.1215	DOI Listing

November 2014

Identification of subgroups of schizophrenia patients with changes in either immune or growth factor and hormonal pathways.

Authors:

Emanuel Schwarz Nico J M van Beveren Jordan Ramsey F Markus Leweke Matthias Rothermundt Bernhard Bogerts Johann Steiner Paul C Guest Sabine Bahn

Schizophr Bull 2014 Jul 9;40(4):787-95. Epub 2013 Aug 9.

Department of Chemical Engineering and Biotechnology, University of Cambridge, Cambridge, UK; Department of Neuroscience, Erasmus University Medical Centre, Rotterdam, the Netherlands

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http://dx.doi.org/10.1093/schbul/sbt105	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4059436	PMC

July 2014

Distinct molecular phenotypes in male and female schizophrenia patients.

Authors:

Jordan M Ramsey Emanuel Schwarz Paul C Guest Nico J M van Beveren F Markus Leweke Matthias Rothermundt Bernhard Bogerts Johann Steiner Sabine Bahn

PLoS One 2013 11;8(11):e78729. Epub 2013 Nov 11.

Department of Chemical Engineering and Biotechnology, University of Cambridge, Cambridge, United Kingdom.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0078729	PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3823995	PMC

July 2014

Identifying gene-environment interactions in schizophrenia: contemporary challenges for integrated, large-scale investigations.

Authors:

Jim van Os Bart P Rutten Inez Myin-Germeys Philippe Delespaul Wolfgang Viechtbauer Catherine van Zelst Richard Bruggeman Ulrich Reininghaus Craig Morgan Robin M Murray Marta Di Forti Philip McGuire Lucia R Valmaggia Matthew J Kempton Charlotte Gayer-Anderson Kathryn Hubbard Stephanie Beards Simona A Stilo Adanna Onyejiaka Francois Bourque Gemma Modinos Stefania Tognin Maria Calem Michael C O'Donovan Michael J Owen Peter Holmans Nigel Williams Nicholas Craddock Alexander Richards Isla Humphreys Andreas Meyer-Lindenberg F Markus Leweke Heike Tost Ceren Akdeniz Cathrin Rohleder J Malte Bumb Emanuel Schwarz Köksal Alptekin Alp Üçok Meram Can Saka E Cem Atbaşoğlu Sinan Gülöksüz Guvem Gumus-Akay Burçin Cihan Hasan Karadağ Haldan Soygür Eylem Şahin Cankurtaran Semra Ulusoy Berna Akdede Tolga Binbay Ahmet Ayer Handan Noyan Gülşah Karadayı Elçin Akturan Halis Ulaş Celso Arango Mara Parellada Miguel Bernardo Julio Sanjuán Julio Bobes Manuel Arrojo Jose Luis Santos Pedro Cuadrado José Juan Rodríguez Solano Angel Carracedo Enrique García Bernardo Laura Roldán Gonzalo López Bibiana Cabrera Sabrina Cruz Eva Ma Díaz Mesa María Pouso Estela Jiménez Teresa Sánchez Marta Rapado Emiliano González Covadonga Martínez Emilio Sánchez Ma Soledad Olmeda Lieuwe de Haan Eva Velthorst Mark van der Gaag Jean-Paul Selten Daniella van Dam Elsje van der Ven Floor van der Meer Elles Messchaert Tamar Kraan Nadine Burger Marion Leboyer Andrei Szoke Franck Schürhoff Pierre-Michel Llorca Stéphane Jamain Andrea Tortelli Flora Frijda Jeanne Vilain Anne-Marie Galliot Grégoire Baudin Aziz Ferchiou Jean-Romain Richard Ewa Bulzacka Thomas Charpeaud Anne-Marie Tronche Marc De Hert Ruud van Winkel Jeroen Decoster Catherine Derom Evert Thiery Nikos C Stefanis Gabriele Sachs Harald Aschauer Iris Lasser Bernadette Winklbaur Monika Schlögelhofer Anita Riecher-Rössler Stefan Borgwardt Anna Walter Fabienne Harrisberger Renata Smieskova Charlotte Rapp Sarah Ittig Fabienne Soguel-dit-Piquard Erich Studerus Joachim Klosterkötter Stephan Ruhrmann Julia Paruch Dominika Julkowski Desiree Hilboll Pak C Sham Stacey S Cherny Eric Y H Chen Desmond D Campbell Miaoxin Li Carlos María Romeo-Casabona Aitziber Emaldi Cirión Asier Urruela Mora Peter Jones James Kirkbride Mary Cannon Dan Rujescu Ilaria Tarricone Domenico Berardi Elena Bonora Marco Seri Thomas Marcacci Luigi Chiri Federico Chierzi Viviana Storbini Mauro Braca Maria Gabriella Minenna Ivonne Donegani Angelo Fioritti Daniele La Barbera Caterina Erika La Cascia Alice Mulè Lucia Sideli Rachele Sartorio Laura Ferraro Giada Tripoli Fabio Seminerio Anna Maria Marinaro Patrick McGorry Barnaby Nelson G Paul Amminger Christos Pantelis Paulo R Menezes Cristina M Del-Ben Silvia H Gallo Tenan Rosana Shuhama Mirella Ruggeri Sarah Tosato Antonio Lasalvia Chiara Bonetto Elisa Ira Merete Nordentoft Marie-Odile Krebs Neus Barrantes-Vidal Paula Cristóbal Thomas R Kwapil Elisa Brietzke Rodrigo A Bressan Ary Gadelha Nadja P Maric Sanja Andric Marina Mihaljevic Tijana Mirjanic

Schizophr Bull 2014 Jul 24;40(4):729-36. Epub 2014 May 24.

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http://dx.doi.org/10.1093/schbul/sbu069	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4059449	PMC

July 2014

Proteomic profiling in schizophrenia: enabling stratification for more effective treatment.

Authors:

Paul C Guest Daniel Martins-de-Souza Emanuel Schwarz Hassan Rahmoune Murtada Alsaif Jakub Tomasik Christoph W Turck Sabine Bahn

Genome Med 2013 26;5(3):25. Epub 2013 Mar 26.

Department of Chemical Engineering and Biotechnology, University of Cambridge, Tennis Court Road, Cambridge, CB2 1QT, UK ; Department of Neuroscience, Erasmus Medical Centre, NL-3000 CA Rotterdam, The Netherlands.

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http://genomemedicine.biomedcentral.com/articles/10.1186/gm4	Publisher Site
http://dx.doi.org/10.1186/gm429	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3706977	PMC

June 2014

Cytokine alterations in first-episode schizophrenia patients before and after antipsychotic treatment.

Authors:

Lot de Witte Jakub Tomasik Emanuel Schwarz Paul C Guest Hassan Rahmoune René S Kahn Sabine Bahn

Schizophr Res 2014 Apr 26;154(1-3):23-9. Epub 2014 Feb 26.

Department of Chemical Engineering and Biotechnology, Tennis Court Road, Cambridge CB21QT, University of Cambridge, UK; Department of Neuroscience, Erasmus Medical Centre, Dr. Molewaterplein 50, 3015 GE, Rotterdam, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.schres.2014.02.005	DOI Listing

April 2014

Identification of a molecular profile associated with immune status in first-onset schizophrenia patients.

Authors:

Marlis Herberth Hassan Rahmoune Emanuel Schwarz Dagmar Koethe Laura W Harris Laura Kranaster Stephanie H Witt Michael Spain Anthony Barnes Manfred Schmolz Markus F Leweke Paul C Guest Sabine Bahn

Clin Schizophr Relat Psychoses 2014 Jan;7(4):207-15

Institute of Biotechnology, University of Cambridge, Tennis Court Road, Cambridge, CB2 1QT, UK.

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http://dx.doi.org/10.3371/CSRP.HERA.020113	DOI Listing

January 2014

Electroconvulsive therapy exerts mainly acute molecular changes in serum of major depressive disorder patients.

Authors:

Viktoria Stelzhammer Paul C Guest Matthias Rothermundt Carina Sondermann Nikolaus Michael Emanuel Schwarz Hassan Rahmoune Sabine Bahn

Eur Neuropsychopharmacol 2013 Oct 22;23(10):1199-207. Epub 2012 Nov 22.

Department of Chemical Engineering and Biotechnology, University of Cambridge, Cambridge, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/j.euroneuro.2012.10.012	DOI Listing

October 2013

Application of meta-analysis methods for identifying proteomic expression level differences.

Authors:

Bob Amess Wolfgang Kluge Emanuel Schwarz Frieder Haenisch Murtada Alsaif Robert H Yolken F Markus Leweke Paul C Guest Sabine Bahn

Proteomics 2013 Jul 6;13(14):2072-6. Epub 2013 Jun 6.

Department of Chemical Engineering and Biotechnology, University of Cambridge, Cambridge, UK.

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http://dx.doi.org/10.1002/pmic.201300034	DOI Listing

July 2013

Molecular sex differences in human serum.

Authors:

Jordan M Ramsey Emanuel Schwarz Paul C Guest Nico J M van Beveren F Markus Leweke Matthias Rothermundt Bernhard Bogerts Johann Steiner Liliana Ruta Simon Baron-Cohen Sabine Bahn

PLoS One 2012 12;7(12):e51504. Epub 2012 Dec 12.

Department of Chemical Engineering and Biotechnology, University of Cambridge, Cambridge, United Kingdom.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0051504	PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3520798	PMC

June 2013

Comparison of peripheral and central schizophrenia biomarker profiles.

Authors:

Laura W Harris Sandra Pietsch Tammy M K Cheng Emanuel Schwarz Paul C Guest Sabine Bahn

PLoS One 2012 30;7(10):e46368. Epub 2012 Oct 30.

Department of Chemical Engineering and Biotechnology, University of Cambridge, Cambridge, United Kingdom.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0046368	PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3484150	PMC

May 2013

Identification of a blood-based biological signature in subjects with psychiatric disorders prior to clinical manifestation.

Authors:

Emanuel Schwarz Paul C Guest Hassan Rahmoune Daniel Martins-de-Souza David W Niebuhr Natalya S Weber David N Cowan Robert H Yolken Michael Spain Anthony Barnes Sabine Bahn

World J Biol Psychiatry 2012 Dec 22;13(8):627-32. Epub 2011 Sep 22.

Department of Chemical Engineering and Biotechnology, University of Cambridge, Cambridge, UK.

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http://dx.doi.org/10.3109/15622975.2011.599861	DOI Listing

December 2012

Blood test for schizophrenia.

Authors:

Jakub Tomasik Emanuel Schwarz Paul C Guest Sabine Bahn

Eur Arch Psychiatry Clin Neurosci 2012 Nov 26;262 Suppl 2:S79-83. Epub 2012 Aug 26.

Department of Chemical Engineering and Biotechnology, University of Cambridge, Cambridge, UK.

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http://dx.doi.org/10.1007/s00406-012-0354-3	DOI Listing

November 2012

Converging evidence of blood-based biomarkers for schizophrenia: an update.

Authors:

Man K Chan Paul C Guest Yishai Levin Yagnesh Umrania Emanuel Schwarz Sabine Bahn Hassan Rahmoune

Int Rev Neurobiol 2011 ;101:95-144

Department of Chemical Engineering and Biotechnology, University of Cambridge, Cambridge, United Kingdom.

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http://dx.doi.org/10.1016/B978-0-12-387718-5.00005-5	DOI Listing

August 2012

The application of multiplexed assay systems for molecular diagnostics.

Authors:

Emanuel Schwarz Nico J M VanBeveren Paul C Guest Rauf Izmailov Sabine Bahn

Int Rev Neurobiol 2011 ;101:259-78

Department of Chemical Engineering and Biotechnology, University of Cambridge, Cambridge, United Kingdom.

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http://dx.doi.org/10.1016/B978-0-12-387718-5.00010-9	DOI Listing

August 2012

Algorithm development for diagnostic biomarker assays.

Authors:

Rauf Izmailov Paul C Guest Sabine Bahn Emanuel Schwarz

Int Rev Neurobiol 2011 ;101:279-98

Rules-Based Medicine, Inc., Austin, Texas, USA.

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http://dx.doi.org/10.1016/B978-0-12-387718-5.00011-0	DOI Listing

August 2012

Challenges of introducing new biomarker products for neuropsychiatric disorders into the market.

Authors:

Sabine Bahn Richard Noll Anthony Barnes Emanuel Schwarz Paul C Guest

Int Rev Neurobiol 2011 ;101:299-327

Department of Chemical Engineering and Biotechnology, University of Cambridge, Cambridge, United Kingdom.

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https://linkinghub.elsevier.com/retrieve/pii/B97801238771850	Publisher Site
http://dx.doi.org/10.1016/B978-0-12-387718-5.00012-2	DOI Listing

August 2012

Differential phosphorylation of serum proteins reflecting inflammatory changes in schizophrenia patients.

Authors:

Julian A J Jaros Daniel Martins-de-Souza Hassan Rahmoune Emanuel Schwarz F Markus Leweke Paul C Guest Sabine Bahn

Eur Arch Psychiatry Clin Neurosci 2012 Aug 15;262(5):453-5. Epub 2011 Dec 15.

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http://link.springer.com/10.1007/s00406-011-0283-6	Publisher Site
http://dx.doi.org/10.1007/s00406-011-0283-6	DOI Listing

August 2012

Molecular validation of the acute phencyclidine rat model for schizophrenia: identification of translational changes in energy metabolism and neurotransmission.

Authors:

Agnes Ernst Dan Ma Isabel Garcia-Perez Tsz M Tsang Wolfgang Kluge Emanuel Schwarz Paul C Guest Elaine Holmes Zoltan Sarnyai Sabine Bahn

J Proteome Res 2012 Jul 1;11(7):3704-14. Epub 2012 Jun 1.

Department of Chemical Engineering and Biotechnology, University of Cambridge, Cambridge CB2 1QT, UK.

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http://dx.doi.org/10.1021/pr300197d	DOI Listing

July 2012

Analysis of serum and plasma identifies differences in molecular coverage, measurement variability, and candidate biomarker selection.

Authors:

Murtada Alsaif Paul C Guest Emanuel Schwarz Andreas Reif Sarah Kittel-Schneider Michael Spain Hassan Rahmoune Sabine Bahn

Proteomics Clin Appl 2012 Jun;6(5-6):297-303

Department of Chemical Engineering and Biotechnology, University of Cambridge, Cambridge, UK.

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http://dx.doi.org/10.1002/prca.201100061	DOI Listing

June 2012

Biomarker discovery in human cerebrospinal fluid: the need for integrative metabolome and proteome databases.

Authors:

Emanuel Schwarz E Fuller Torrey Paul C Guest Sabine Bahn

Genome Med 2012 Apr 30;4(4):39. Epub 2012 Apr 30.

Institute of Biotechnology, University of Cambridge, Cambridge CB2 1QT, UK.

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http://genomemedicine.biomedcentral.com/articles/10.1186/gm3	Publisher Site
http://dx.doi.org/10.1186/gm338	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3446267	PMC

April 2012

Translating potential biomarker candidates for schizophrenia and depression to animal models of psychiatric disorders.

Authors:

Wolfgang Kluge Murtada Alsaif Paul C Guest Emanuel Schwarz Sabine Bahn

Expert Rev Mol Diagn 2011 Sep;11(7):721-33

Institute of Biotechnology, University of Cambridge, Cambridge, UK.

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http://dx.doi.org/10.1586/erm.11.61	DOI Listing

September 2011

Altered levels of circulating insulin and other neuroendocrine hormones associated with the onset of schizophrenia.

Authors:

Paul C Guest Emanuel Schwarz Divya Krishnamurthy Laura W Harris F Markus Leweke Matthias Rothermundt Nico J M van Beveren Michael Spain Anthony Barnes Johann Steiner Hassan Rahmoune Sabine Bahn

Psychoneuroendocrinology 2011 Aug 20;36(7):1092-6. Epub 2011 Jan 20.

Department of Chemical Engineering and Biotechnology, University of Cambridge, Tennis Court Road, Cambridge, UK.

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http://dx.doi.org/10.1016/j.psyneuen.2010.12.018	DOI Listing

August 2011

Peripheral profiling analysis for bipolar disorder reveals markers associated with reduced cell survival.

Authors:

Marlis Herberth Dagmar Koethe Yishai Levin Emanuel Schwarz Natalia D Krzyszton Stephanie Schoeffmann Hermelindis Ruh Hassan Rahmoune Laura Kranaster Torsten Schoenborn Markus F Leweke Paul C Guest Sabine Bahn

Proteomics 2011 Jan 6;11(1):94-105. Epub 2010 Dec 6.

Institute of Biotechnology, University of Cambridge, Tennis Court Road, Cambridge, UK.

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http://dx.doi.org/10.1002/pmic.201000291	DOI Listing

January 2011

Alterations of primary fatty acid amides in serum of patients with severe mental illness.

Authors:

Emanuel Schwarz Phil Whitfield Sven Nahnsen Lan Wang Hilary Major F Markus Leweke Dagmar Koethe Pietro Lio Sabine Bahn

Front Biosci (Elite Ed) 2011 Jan 1;3:308-14. Epub 2011 Jan 1.

Institute of Biotechnology, University of Cambridge, Cambridge, UK.

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http://dx.doi.org/10.2741/e246	DOI Listing

January 2011

Validation of a blood-based laboratory test to aid in the confirmation of a diagnosis of schizophrenia.

Biomark Insights 2010 May 12;5:39-47. Epub 2010 May 12.

Institute of Biotechnology, University of Cambridge, Cambridge, UK (consultants to Rules-Based Medicine).

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2879227	PMC
http://dx.doi.org/10.4137/bmi.s4877	DOI Listing

May 2010

Multidimensional protein fractionation of blood proteins coupled to data-independent nanoLC-MS/MS analysis.

Authors:

Yishai Levin Julian A J Jaros Emanuel Schwarz Sabine Bahn

J Proteomics 2010 Jan 5;73(3):689-95. Epub 2009 Nov 5.

Cambridge Centre for Neuropsychiatric Research, Institute of Biotechnology, Department of Chemical Engineering and Biotechnology, University of Cambridge, Tennis Court Road, CB 2 1QT Cambridge, United Kingdom.

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