Publications by authors named "Emanuel Schwarz"

72Publications

The genetic architecture of human brainstem structures and their involvement in common brain disorders.

Nat Commun 2020 08 11;11(1):4016. Epub 2020 Aug 11.

NORMENT, Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway.

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August 2020

Identification of Reproducible BCL11A Alterations in Schizophrenia Through Individual-Level Prediction of Coexpression.

Schizophr Bull 2020 Mar 31. Epub 2020 Mar 31.

Department of Psychiatry and Psychotherapy, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.

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March 2020

Publisher Correction: Common brain disorders are associated with heritable patterns of apparent aging of the brain.

Nat Neurosci 2020 Feb;23(2):295

NORMENT, Division of Mental Health and Addiction Oslo University Hospital & Institute of Clinical Medicine, University of Oslo, Oslo, Norway.

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February 2020

Common brain disorders are associated with heritable patterns of apparent aging of the brain.

Nat Neurosci 2019 10 24;22(10):1617-1623. Epub 2019 Sep 24.

NORMENT, Division of Mental Health and Addiction Oslo University Hospital & Institute of Clinical Medicine, University of Oslo, Oslo, Norway.

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October 2019

Neural correlates of individual differences in affective benefit of real-life urban green space exposure.

Nat Neurosci 2019 09 29;22(9):1389-1393. Epub 2019 Jul 29.

Department of Psychiatry and Psychotherapy, Central Institute of Mental Health, University of Heidelberg, Medical Faculty Mannheim, Mannheim, Baden-Wuerttemberg, Germany.

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September 2019

Computational Approaches for Identification of Pleiotropic Biomarker Profiles in Psychiatry.

Adv Exp Med Biol 2019 ;1134:111-128

Department of Psychiatry and Psychotherapy, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.

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August 2019

Comparative Evaluation of Machine Learning Strategies for Analyzing Big Data in Psychiatry.

Int J Mol Sci 2018 Oct 29;19(11). Epub 2018 Oct 29.

Department of Psychiatry and Psychotherapy, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, 68159 Mannheim, Germany.

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October 2018

Resting-state brain network features associated with short-term skill learning ability in humans and the influence of -methyl-d-aspartate receptor antagonism.

Netw Neurosci 2018 1;2(4):464-480. Epub 2018 Oct 1.

Department of Psychiatry and Psychotherapy, Research Group System Neuroscience in Psychiatry, Central Institute of Mental Health, University of Heidelberg, Medical Faculty Mannheim, Mannheim, Germany.

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October 2018

RMTL: an R library for multi-task learning.

Bioinformatics 2019 05;35(10):1797-1798

Department of Psychiatry and Psychotherapy, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.

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May 2019

Gimpute: an efficient genetic data imputation pipeline.

Bioinformatics 2019 04;35(8):1433-1435

Department of Psychiatry and Psychotherapy, Heidelberg University, Mannheim, Germany.

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April 2019

Male increase in brain gene expression variability is linked to genetic risk for schizophrenia.

Transl Psychiatry 2018 08 1;8(1):140. Epub 2018 Aug 1.

Medical Faculty Mannheim, Department of Psychiatry and Psychotherapy, Central Institute of Mental Health, Heidelberg University, Mannheim, Germany.

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August 2018

A polygenic score for schizophrenia predicts glycemic control.

Transl Psychiatry 2017 12 18;7(12):1295. Epub 2017 Dec 18.

Department of Psychiatry and Psychotherapy, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.

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December 2017

A gene-based review of RGS4 as a putative risk gene for psychiatric illness.

Authors:
Emanuel Schwarz

Am J Med Genet B Neuropsychiatr Genet 2018 03 24;177(2):267-273. Epub 2017 May 24.

Medical Faculty Mannheim, Department of Psychiatry and Psychotherapy, Central Institute of Mental Health, Heidelberg University, Mannheim, Germany.

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March 2018

Multiplex Immunoassay Profiling of Serum in Psychiatric Disorders.

Adv Exp Med Biol 2017 ;974:149-156

Laboratory of Neuroproteomics, Department of Biochemistry and Tissue Biology, Institute of Biology, University of Campinas (UNICAMP), Rua Monteiro Lobato 255 F/01, Cidade Universitária ZeferinoVaz, 13083-862, Campinas, Brazil.

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September 2017

The Utility of Multiplex Assays for Identification of Proteomic Signatures in Psychiatry.

Adv Exp Med Biol 2017 ;974:131-138

Department of Psychiatry and Psychotherapy, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.

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September 2017

Opportunities and Challenges of Multiplex Assays: A Machine Learning Perspective.

Methods Mol Biol 2017 ;1546:115-122

Department of Psychiatry and Psychotherapy, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, J 5, Mannheim, 68159, Germany.

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February 2018

Identification and Clinical Translation of Biomarker Signatures: Statistical Considerations.

Authors:
Emanuel Schwarz

Methods Mol Biol 2017 ;1546:103-114

Department of Psychiatry and Psychotherapy, Medical Faculty Mannheim, Central Institute of Mental Health, Heidelberg University, Mannheim, Germany.

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February 2018

Association of anandamide with altered binocular depth inversion illusion in schizophrenia.

World J Biol Psychiatry 2017 09 11;18(6):483-488. Epub 2016 Nov 11.

a Department of Psychiatry and Psychotherapy , Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University , Mannheim , Germany.

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September 2017

The association of pineal gland volume and body mass in obese and normal weight individuals: a pilot study.

Psychiatr Danub 2016 Sep;28(3):220-224

Department of Addictive Behaviour and Addiction Medicine, Central Institute of Mental Health, Medical Faculty Mannheim/University of Heidelberg, Mannheim, Germany.

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September 2016

Protein Interaction Networks Link Schizophrenia Risk Loci to Synaptic Function.

Schizophr Bull 2016 11 7;42(6):1334-1342. Epub 2016 Apr 7.

Department of Psychiatry and Psychotherapy, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.

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November 2016

Pretreatment levels of the fatty acid handling proteins H-FABP and CD36 predict response to olanzapine in recent-onset schizophrenia patients.

Brain Behav Immun 2016 Feb 2;52:178-186. Epub 2015 Nov 2.

Department of Chemical Engineering and Biotechnology, University of Cambridge, Cambridge, UK; Department of Neuroscience, Erasmus Medical Centre, Rotterdam, The Netherlands. Electronic address:

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February 2016

Working memory genetics in schizophrenia and related disorders: An RDoC perspective.

Am J Med Genet B Neuropsychiatr Genet 2016 Jan 14;171B(1):121-31. Epub 2015 Sep 14.

Department of Psychiatry and Psychotherapy, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.

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January 2016

Neural Correlates of the Cortisol Awakening Response in Humans.

Neuropsychopharmacology 2015 Aug 17;40(9):2278-85. Epub 2015 Mar 17.

Central Institute for Mental Health, University of Heidelberg/Medical Faculty Mannheim, J5, Mannheim, Germany.

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August 2015

IgG dynamics of dietary antigens point to cerebrospinal fluid barrier or flow dysfunction in first-episode schizophrenia.

Brain Behav Immun 2015 Feb 20;44:148-58. Epub 2014 Sep 20.

Department of Psychiatry and Psychotherapy, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.

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February 2015

Oleoylethanolamide and human neural responses to food stimuli in obesity.

JAMA Psychiatry 2014 Nov;71(11):1254-61

Department of Psychiatry and Psychotherapy, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.

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November 2014

Identifying gene-environment interactions in schizophrenia: contemporary challenges for integrated, large-scale investigations.

Authors:
Jim van Os Bart P Rutten Inez Myin-Germeys Philippe Delespaul Wolfgang Viechtbauer Catherine van Zelst Richard Bruggeman Ulrich Reininghaus Craig Morgan Robin M Murray Marta Di Forti Philip McGuire Lucia R Valmaggia Matthew J Kempton Charlotte Gayer-Anderson Kathryn Hubbard Stephanie Beards Simona A Stilo Adanna Onyejiaka Francois Bourque Gemma Modinos Stefania Tognin Maria Calem Michael C O'Donovan Michael J Owen Peter Holmans Nigel Williams Nicholas Craddock Alexander Richards Isla Humphreys Andreas Meyer-Lindenberg F Markus Leweke Heike Tost Ceren Akdeniz Cathrin Rohleder J Malte Bumb Emanuel Schwarz Köksal Alptekin Alp Üçok Meram Can Saka E Cem Atbaşoğlu Sinan Gülöksüz Guvem Gumus-Akay Burçin Cihan Hasan Karadağ Haldan Soygür Eylem Şahin Cankurtaran Semra Ulusoy Berna Akdede Tolga Binbay Ahmet Ayer Handan Noyan Gülşah Karadayı Elçin Akturan Halis Ulaş Celso Arango Mara Parellada Miguel Bernardo Julio Sanjuán Julio Bobes Manuel Arrojo Jose Luis Santos Pedro Cuadrado José Juan Rodríguez Solano Angel Carracedo Enrique García Bernardo Laura Roldán Gonzalo López Bibiana Cabrera Sabrina Cruz Eva Ma Díaz Mesa María Pouso Estela Jiménez Teresa Sánchez Marta Rapado Emiliano González Covadonga Martínez Emilio Sánchez Ma Soledad Olmeda Lieuwe de Haan Eva Velthorst Mark van der Gaag Jean-Paul Selten Daniella van Dam Elsje van der Ven Floor van der Meer Elles Messchaert Tamar Kraan Nadine Burger Marion Leboyer Andrei Szoke Franck Schürhoff Pierre-Michel Llorca Stéphane Jamain Andrea Tortelli Flora Frijda Jeanne Vilain Anne-Marie Galliot Grégoire Baudin Aziz Ferchiou Jean-Romain Richard Ewa Bulzacka Thomas Charpeaud Anne-Marie Tronche Marc De Hert Ruud van Winkel Jeroen Decoster Catherine Derom Evert Thiery Nikos C Stefanis Gabriele Sachs Harald Aschauer Iris Lasser Bernadette Winklbaur Monika Schlögelhofer Anita Riecher-Rössler Stefan Borgwardt Anna Walter Fabienne Harrisberger Renata Smieskova Charlotte Rapp Sarah Ittig Fabienne Soguel-dit-Piquard Erich Studerus Joachim Klosterkötter Stephan Ruhrmann Julia Paruch Dominika Julkowski Desiree Hilboll Pak C Sham Stacey S Cherny Eric Y H Chen Desmond D Campbell Miaoxin Li Carlos María Romeo-Casabona Aitziber Emaldi Cirión Asier Urruela Mora Peter Jones James Kirkbride Mary Cannon Dan Rujescu Ilaria Tarricone Domenico Berardi Elena Bonora Marco Seri Thomas Marcacci Luigi Chiri Federico Chierzi Viviana Storbini Mauro Braca Maria Gabriella Minenna Ivonne Donegani Angelo Fioritti Daniele La Barbera Caterina Erika La Cascia Alice Mulè Lucia Sideli Rachele Sartorio Laura Ferraro Giada Tripoli Fabio Seminerio Anna Maria Marinaro Patrick McGorry Barnaby Nelson G Paul Amminger Christos Pantelis Paulo R Menezes Cristina M Del-Ben Silvia H Gallo Tenan Rosana Shuhama Mirella Ruggeri Sarah Tosato Antonio Lasalvia Chiara Bonetto Elisa Ira Merete Nordentoft Marie-Odile Krebs Neus Barrantes-Vidal Paula Cristóbal Thomas R Kwapil Elisa Brietzke Rodrigo A Bressan Ary Gadelha Nadja P Maric Sanja Andric Marina Mihaljevic Tijana Mirjanic

Schizophr Bull 2014 Jul 24;40(4):729-36. Epub 2014 May 24.

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July 2014

Cytokine alterations in first-episode schizophrenia patients before and after antipsychotic treatment.

Schizophr Res 2014 Apr 26;154(1-3):23-9. Epub 2014 Feb 26.

Department of Chemical Engineering and Biotechnology, Tennis Court Road, Cambridge CB21QT, University of Cambridge, UK; Department of Neuroscience, Erasmus Medical Centre, Dr. Molewaterplein 50, 3015 GE, Rotterdam, The Netherlands. Electronic address:

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April 2014

Distinct molecular phenotypes in male and female schizophrenia patients.

PLoS One 2013 11;8(11):e78729. Epub 2013 Nov 11.

Department of Chemical Engineering and Biotechnology, University of Cambridge, Cambridge, United Kingdom.

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July 2014

Investigation of molecular serum profiles associated with predisposition to antipsychotic-induced weight gain.

World J Biol Psychiatry 2015 Jan 3;16(1):22-30. Epub 2013 Sep 3.

Department of Chemical Engineering and Biotechnology, University of Cambridge , Cambridge , UK.

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January 2015

Identification of subgroups of schizophrenia patients with changes in either immune or growth factor and hormonal pathways.

Schizophr Bull 2014 Jul 9;40(4):787-95. Epub 2013 Aug 9.

Department of Chemical Engineering and Biotechnology, University of Cambridge, Cambridge, UK; Department of Neuroscience, Erasmus University Medical Centre, Rotterdam, the Netherlands

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July 2014

Application of meta-analysis methods for identifying proteomic expression level differences.

Proteomics 2013 Jul 6;13(14):2072-6. Epub 2013 Jun 6.

Department of Chemical Engineering and Biotechnology, University of Cambridge, Cambridge, UK.

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July 2013

Proteomic profiling in schizophrenia: enabling stratification for more effective treatment.

Genome Med 2013 26;5(3):25. Epub 2013 Mar 26.

Department of Chemical Engineering and Biotechnology, University of Cambridge, Tennis Court Road, Cambridge, CB2 1QT, UK ; Department of Neuroscience, Erasmus Medical Centre, NL-3000 CA Rotterdam, The Netherlands.

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June 2014

Molecular sex differences in human serum.

PLoS One 2012 12;7(12):e51504. Epub 2012 Dec 12.

Department of Chemical Engineering and Biotechnology, University of Cambridge, Cambridge, United Kingdom.

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June 2013

Electroconvulsive therapy exerts mainly acute molecular changes in serum of major depressive disorder patients.

Eur Neuropsychopharmacol 2013 Oct 22;23(10):1199-207. Epub 2012 Nov 22.

Department of Chemical Engineering and Biotechnology, University of Cambridge, Cambridge, United Kingdom. Electronic address:

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October 2013

Comparison of peripheral and central schizophrenia biomarker profiles.

PLoS One 2012 30;7(10):e46368. Epub 2012 Oct 30.

Department of Chemical Engineering and Biotechnology, University of Cambridge, Cambridge, United Kingdom.

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May 2013

Blood test for schizophrenia.

Eur Arch Psychiatry Clin Neurosci 2012 Nov 26;262 Suppl 2:S79-83. Epub 2012 Aug 26.

Department of Chemical Engineering and Biotechnology, University of Cambridge, Cambridge, UK.

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November 2012

Biomarker discovery in human cerebrospinal fluid: the need for integrative metabolome and proteome databases.

Genome Med 2012 Apr 30;4(4):39. Epub 2012 Apr 30.

Institute of Biotechnology, University of Cambridge, Cambridge CB2 1QT, UK.

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April 2012

Challenges of introducing new biomarker products for neuropsychiatric disorders into the market.

Int Rev Neurobiol 2011 ;101:299-327

Department of Chemical Engineering and Biotechnology, University of Cambridge, Cambridge, United Kingdom.

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August 2012

Algorithm development for diagnostic biomarker assays.

Int Rev Neurobiol 2011 ;101:279-98

Rules-Based Medicine, Inc., Austin, Texas, USA.

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August 2012

The application of multiplexed assay systems for molecular diagnostics.

Int Rev Neurobiol 2011 ;101:259-78

Department of Chemical Engineering and Biotechnology, University of Cambridge, Cambridge, United Kingdom.

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August 2012

Converging evidence of blood-based biomarkers for schizophrenia: an update.

Int Rev Neurobiol 2011 ;101:95-144

Department of Chemical Engineering and Biotechnology, University of Cambridge, Cambridge, United Kingdom.

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August 2012

Alterations of primary fatty acid amides in serum of patients with severe mental illness.

Front Biosci (Elite Ed) 2011 Jan 1;3:308-14. Epub 2011 Jan 1.

Institute of Biotechnology, University of Cambridge, Cambridge, UK.

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January 2011

Multidimensional protein fractionation of blood proteins coupled to data-independent nanoLC-MS/MS analysis.

J Proteomics 2010 Jan 5;73(3):689-95. Epub 2009 Nov 5.

Cambridge Centre for Neuropsychiatric Research, Institute of Biotechnology, Department of Chemical Engineering and Biotechnology, University of Cambridge, Tennis Court Road, CB 2 1QT Cambridge, United Kingdom.

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January 2010

Clinical bioinformatics for complex disorders: a schizophrenia case study.

BMC Bioinformatics 2009 Oct 15;10 Suppl 12:S6. Epub 2009 Oct 15.

Institute of Biotechnology, University of Cambridge, Tennis Court Road, Cambridge, UK.

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October 2009

Real-time evaluation of experimental variation in large-scale LC-MS/MS-based quantitative proteomics of complex samples.

J Chromatogr B Analyt Technol Biomed Life Sci 2009 May 13;877(13):1299-305. Epub 2008 Nov 13.

Institute of Biotechnology, University of Cambridge, Tennis Court Road, Cambridge CB2 1QT, UK.

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May 2009

Biomarker discovery in psychiatric disorders.

Electrophoresis 2008 Jul;29(13):2884-90

Institute of Biotechnology, University of Cambridge, Cambridge, UK.

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July 2008

Cerebrospinal fluid: identification of diagnostic markers for schizophrenia.

Expert Rev Mol Diagn 2008 Mar;8(2):209-16

Institute of Biotechnology, University of Cambridge, Tennis Court Road, Cambridge CB2 1QT, UK.

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March 2008

Label-free LC-MS/MS quantitative proteomics for large-scale biomarker discovery in complex samples.

J Sep Sci 2007 Sep;30(14):2198-203

Institute of Biotechnology, University of Cambridge, Cambridge, UK.

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September 2007