Publications by authors named "Elouazzani Hafsa"

10 Publications

  • Page 1 of 1

Concurrent Angiomyolipoma and Clear Cell Renal Cell Carcinoma in the Same Kidney: A Rare Finding in a Patient without Tuberous Sclerosis.

Case Rep Urol 2021 1;2021:6663369. Epub 2021 Sep 1.

Department of Pathology, Ibn Sina University Hospital Center, Rabat, Morocco.

Synchronous renal cell carcinomas (RCC) and angiomyolipomas (AML) occurring in the same kidney are rare. Cases in the setting of tuberous sclerosis (TS) have been reported in the literature. However, the association of these tumors in the same kidney without TS is even more rare. We report here a case of a clear cell renal cell carcinoma (CCRCC) associated with an AML in the same kidney in a 42 years old female lacking the TS diagnostic criteria. The patient underwent a radical nephrectomy. Six months after surgery, the patient is healthy without signs of tumor recurrence or distant metastasis.
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http://dx.doi.org/10.1155/2021/6663369DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8426085PMC
September 2021

Leiomyosarcoma of the Renal Vein Mimicking a Primitive Renal Cell Carcinoma: Case Report of an Unusual Presentation.

Case Rep Pathol 2021 12;2021:6637533. Epub 2021 May 12.

Department of Pathology, Ibn Sina University Hospital Center, Rabat, Morocco.

Primary leiomyosarcomas (LMS) of vascular origin are rare tumors, and more than half of the cases arise in the inferior vena cava (IVC). Primary LMS of the renal vein are extremely rare tumors with only a few cases reported in the literature. Their diagnosis is made only by pathological features. Histologically, they are made of atypical spindle-shaped cells arranged in long intersecting fascicles. Tumor cells stain positive for myogenic markers in immunohistochemistry. Standard treatment consists of radical nephrectomy followed by chemotherapy and/or radiotherapy. Because of insufficient histological data and follow-up, the prognosis factors are not well identified. Overall prognosis of renal vein LMS is poor. We report here an exceptional case of a huge LMS of the right renal vein mimicking a primitive renal cell carcinoma, occurring in a 56-year-old male patient.
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http://dx.doi.org/10.1155/2021/6637533DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8133846PMC
May 2021

[Therapeutic management and prognostic profile of a patient with maxillary sarcomatoid carcinoma (case report)].

Pan Afr Med J 2021 24;38:212. Epub 2021 Feb 24.

Service de Chirurgie Maxillo-faciale et Stomatologie, Centre Hospitalier Universitaire, Rabat, Maroc.

Sarcomatoid carcinoma is a rare, aggressive, malignant tumor with a poor prognosis and a very high frequency of recurrence. Carcinoma of the maxillary sinus is extremely rare. We report the case of a 42-year-old woman with left maxillary process. Biopsy revealed aggressive sarcomatoid carcinoma with a lymph-node metastasis. The patient underwent surgical excision, lymph-node dissection followed by radiotherapy with good outcome. The rarity of this site-specific cancer poses a problem of diagnosis and timely management which is still a controversial topic. However, wide surgical excision is the gold standard treatment. This study highlights the anatomoclinical peculiarities and, in particular, the prognostic features of this tumor.
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http://dx.doi.org/10.11604/pamj.2021.38.212.26602DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8140686PMC
June 2021

Retroperitoneal leiomyoma of gynecologic type: a case report and review of the litterature.

J Surg Case Rep 2020 Dec 24;2020(12):rjaa489. Epub 2020 Dec 24.

Department of Pathology, Ibn Sina Teaching Hospital, Rabat, Morocco.

Retroperitoneal leiomyomas are rare benign tumors with smooth muscle differentiation, with only ~1001 cases reported in the English literature to date. Because of its scarcity and non-specific presentation, the preoperative diagnosis might be challenging. On histology, these neoplasms share the same macroscopic, morphological and phenotypic features with uterine leiomyoma; thus, they are referred to as leiomyoma of gynecologic type. Herein, we describe a case of a voluminous retroperitoneal leiomyoma in a 51-year-old woman with a history of total hysterectomy to raise awareness about this condition, as its differential diagnosis might be challenging.
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http://dx.doi.org/10.1093/jscr/rjaa489DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7758995PMC
December 2020

Calcifying Fibrous Tumor of the Mesentery: A Case Report and a Review of the Literature.

Clin Pathol 2020 Jan-Dec;13:2632010X20930689. Epub 2020 Jun 23.

Department of Pathology, Ibn Sina Teaching Hospital, Rabat, Morocco.

Background: Calcifying fibrous tumor (CFT) is a rare entity, with a distinctive histological presentation, initially reported as childhood fibrous tumor with psammoma bodies. It is a benign hypocellular fibrous neoplasm calcifications and lymphoplasmacytic infiltrate. The CFTs may involve many sites, including gastrointestinal tract, pleura, abdominal cavity, and neck. The diagnosis might be challenging due to histological overlaps with other mesenchymal tumors. The prognosis is good. We describe herein the case of a 53-year-old woman with an incidentally diagnosed CFT of the mesentery.

Case Presentation: A 53-year-old woman presented to the surgery department with a 2-year history of an anterior abdominal hernia. A computed tomographic scan of the abdomen failed to demonstrate any evidence of a mesenteric nodule. The patient underwent surgical treatment. Careful exploration during the excision of herniated sac revealed a solitary nodule of the mesentery. Local excision was performed. On gross, it was a well-demarcated nodule. Microscopically, the tumor consisted of an abundant paucicellular hyalinized collagen with calcifications; associated to a sparse mononuclear inflammatory infiltrate.

Conclusions: Calcifying fibrous tumor is a benign lesion. The diagnosis is based on histology, because clinical and radiological features are nonspecific. Awareness of this entity is crucial to distinguish it from other mesenchymal tumors especially in the gastrointestinal tract.
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http://dx.doi.org/10.1177/2632010X20930689DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7313334PMC
June 2020

Pelvic angiomyofibroblastoma: an unusual case report.

J Surg Case Rep 2020 May 23;2020(5):rjaa051. Epub 2020 May 23.

Department of Pathology, IBN Sina University Hospital Center, Rabat, Morocco.

Angiomyofibroblastoma is a rare mesenchymal benign tumor that frequently occurs in young- to middle-aged women, arising from the genital tract. There are many overlapping radiological and immunohistochemical features with other stromal cell lesions, making the diagnosis difficult. We report here a case of a 29-year-old woman admitted for a pelvic mass, in whom, the histopathological and immunohistochemical studies led to the diagnosis of angiomyofibroblastoma.
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http://dx.doi.org/10.1093/jscr/rjaa051DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7246335PMC
May 2020

Solitary preperitoneal neurofibroma: a case report.

BMC Res Notes 2015 Apr 1;8:115. Epub 2015 Apr 1.

Department of Visceral Surgical Emergency, Ibn Sina Hospital, Rabat, Morocco.

Background: Neurofibroma is a rare benign tumor. The isolated presence of such lesions in the preperitoneal space with no evidence of systemic disease has never been reported in the literature.

Case Presentation: A 29-year-old white man presented with a 12 months history of progressive abdominal distension. Clinical examination revealed a bulky hypogastric mass. Abdominal computed tomography and pelvic magnetic resonance imaging showed a large, well defined preperitoneal tumor measuring 18 x 17 cm extending in the pelvis. A computed tomography guided biopsy was performed which revealed a neurofibroma. Exploratory laparotomy showed a well encapsulated elastic soft tumor in the preperitoneal space which measured 17 x 18 cm and weighted 2 Kg. The tumor was completely excised. No recurrence occurred after one year of follow-up.

Conclusion: Solitary preperitoneal neurofibroma is an extremely rare benign tumor. Its clinical and radiological signs are nonspecific. Preoperative histology can be useful to guide the surgical approach which is the only curative treatment.
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http://dx.doi.org/10.1186/s13104-015-1098-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4384358PMC
April 2015

Juxtaglomerular cell tumor: a distinct mesenchymal tumor of kidney.

J Clin Imaging Sci 2014 30;4:33. Epub 2014 Jun 30.

Department of Pathology, Ibn Sina Hospital, Rabat, Morocco.

Juxtaglomerular cell tumor (JGCT) is an unusual mesenchymal entity of the kidney. It is a benign renin-secreting tumor causing hypertension and hypokalemia due to secondary hyperaldosteronism. It is curable if it is discovered early and surgically removed, but may cause a fatal outcome usually due to complications of associated hypertension.
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http://dx.doi.org/10.4103/2156-7514.135482DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4142465PMC
August 2014

Primary endobronchial leiomyosarcoma of the lung: clinical, gross and microscopic findings of two cases.

J Clin Imaging Sci 2012 29;2:35. Epub 2012 Jun 29.

Department of Pathology, Ibn Sina Hospital, Rabat, Morocco.

Primary leiomyosarcoma of the lung is an unusual malignant tumor. Among this entity, the endobronchial form is very rare and the preoperative diagnosis is extremely difficult. We present two different presentations and outcomes of primary endobronchial leiomyosarcoma of the lung. In both cases, the histological study and the immunohistochemical stain, of the surgical resection, provided the final diagnosis. Through those cases we present the diagnostic and therapeutic difficulties encountered.
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http://dx.doi.org/10.4103/2156-7514.97757DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3424854PMC
October 2012

Calcified multilocular thymic cyst associated with thymoma: a case report.

J Med Case Rep 2011 Jun 21;5:225. Epub 2011 Jun 21.

Department of Pathology, Ibn Sina Hospital, Rabat, Morocco.

Introduction: There are few case reports of thymoma with a thymic cyst. Such an association renders it difficult for any pathologist to differentiate from other neoplasms, such as a cystic thymoma.

Case Presentation: A 50-year-old Berber woman from Morocco was admitted with a chronic cough of more than 10 years duration. Her medical history and physical examination were normal. Anterior chest radiography demonstrated a calcified opacity in her right anterior mediastinum. A chest-computed tomogram revealed a round cystic tumor, with significant calcification in her right anterior mediastinum. A surgical exploration was performed. The tumor seemed to be a well-encapsulated and totally calcified lesion, arising from the right lobe of her thymus. It was removed by partial resection of her thymus. Through histology, the calcified tumor exhibited some areas of multilocular fibrous-wall cysts. These cysts were partially lined by small cuboidal cells with severe chronic inflammation and an AB thymoma that arose from the wall of the cyst.

Conclusion: Greater attention should be given to multilocular thymic cysts, to exclude the possibility of neoplasm, especially when the cyst wall is thickened.
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http://dx.doi.org/10.1186/1752-1947-5-225DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3130682PMC
June 2011
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