Publications by authors named "Elmar Jaeckel"

68Publications

Non-invasive screening for subclinical liver graft injury in adults via donor-specific anti-HLA antibodies.

Sci Rep 2020 Aug 28;10(1):14242. Epub 2020 Aug 28.

Department of Gastroenterology, Hepatology and Endocrinology, Hannover Medical School, Hannover, Germany.

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http://dx.doi.org/10.1038/s41598-020-70938-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7455737PMC
August 2020

The future of autoimmune liver diseases - Understanding pathogenesis and improving morbidity and mortality.

Liver Int 2020 02;40 Suppl 1:149-153

Department of Gastroenterology, Hepatology and Endocrinology, Hannover Medical School, Hannover, Germany.

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http://dx.doi.org/10.1111/liv.14378DOI Listing
February 2020

Autoimmune hepatitis induction can occur in the liver.

Liver Int 2020 02 1;40(2):377-381. Epub 2019 Dec 1.

Department of Gastroenterology, Hepatology & Endocrinology, Hannover Medical School, Hannover, Germany.

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http://dx.doi.org/10.1111/liv.14296DOI Listing
February 2020

Regulatory T cells engineered with a novel insulin-specific chimeric antigen receptor as a candidate immunotherapy for type 1 diabetes.

J Autoimmun 2019 09 5;103:102289. Epub 2019 Jun 5.

Dept. of Gastroenterology, Hepatology & Endocrinology, Hannover Medical School, Hannover, Germany; Dept. of Gastroenterology and Hepatology, University Hospital Essen, University of Duisburg-Essen, Essen, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.jaut.2019.05.017DOI Listing
September 2019

Tipping the Balance.

Transplantation 2019 01;103(1):4-6

Department of Gastroenterology, Hepatology and Endocrinology, Hannover Medical School, Hannover, Germany.

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http://dx.doi.org/10.1097/TP.0000000000002506DOI Listing
January 2019

Editorial: "real world data" of AIH-time to connect!

Aliment Pharmacol Ther 2018 12;48(11-12):1315-1316

Department of Gastroenterology, Hepatology and Endocrinology, Hannover Medical School (MHH), Hannover, Germany.

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http://doi.wiley.com/10.1111/apt.15028
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http://dx.doi.org/10.1111/apt.15028DOI Listing
December 2018

Novel therapeutic targets in autoimmune hepatitis.

J Autoimmun 2018 12 4;95:34-46. Epub 2018 Nov 4.

Department of Gastroenterology, Hepatology and Endocrinology, Hannover Medical School, Hannover, Germany; German Centre for Infection Research (DZIF), Partner Site Hannover-Braunschweig, Germany; Helmholtz Centre for Infection Research (HZI), Braunschweig, Germany. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S08968411183060
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http://dx.doi.org/10.1016/j.jaut.2018.10.022DOI Listing
December 2018

Increased apoptosis of regulatory T cells in patients with active autoimmune hepatitis.

Cell Death Dis 2017 12 14;8(12):3219. Epub 2017 Dec 14.

Department of Gastroenterology, Hepatology and Endocrinology, Hannover Medical School, Hannover, Germany.

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http://dx.doi.org/10.1038/s41419-017-0010-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5870592PMC
December 2017

Budesonide in Autoimmune Hepatitis: The Right Drug at the Right Time for the Right Patient.

Clin Gastroenterol Hepatol 2018 02 8;16(2):186-189. Epub 2017 Nov 8.

Department of Gastroenterology, Hepatology and Endocrinology, Hannover Medical School, Hannover, Germany.

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http://dx.doi.org/10.1016/j.cgh.2017.11.003DOI Listing
February 2018

Hepatic T Cell Tolerance Induction in An Inflammatory Environment.

Dig Dis 2018 12;36(2):156-166. Epub 2017 Oct 12.

Department of Gastroenterology, Hepatology and Endocrinology, Hannover Medical School, Hannover, Germany.

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http://dx.doi.org/10.1159/000481341DOI Listing
May 2018

Silymarin for Treatment of Nonalcoholic Steatohepatitis-A New Kid on the Block?

Clin Gastroenterol Hepatol 2017 12 10;15(12):1863-1865. Epub 2017 Aug 10.

Department of Gastroenterology, Hepatology and Endocrinology, Hannover Medical School, Hannover, Germany; Helmholtz Centre for Infection Research, Braunschweig, Germany.

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https://linkinghub.elsevier.com/retrieve/pii/S15423565173093
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http://dx.doi.org/10.1016/j.cgh.2017.08.005DOI Listing
December 2017

Insulin degludec/liraglutide (IDegLira) was effective across a range of dysglycaemia and body mass index categories in the DUAL V randomized trial.

Diabetes Obes Metab 2018 01 31;20(1):200-205. Epub 2017 Jul 31.

Department of Endocrinology and Clinical Nutrition, University Hospital Quiron Salud Madrid, Universidad Europea de Madrid, Madrid, Spain.

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http://dx.doi.org/10.1111/dom.13043DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5763397PMC
January 2018

Sonderforschungsbereich SFB 738: Optimierung konventioneller und innovativer Transplantate.

Z Gastroenterol 2017 04 20;55(4):401-404. Epub 2017 Apr 20.

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http://dx.doi.org/10.1055/s-0043-101946DOI Listing
April 2017

Home-based drainage of refractory ascites by a permanent-tunneled peritoneal catheter can safely replace large-volume paracentesis.

Eur J Gastroenterol Hepatol 2017 May;29(5):539-546

aDepartment of Gastroenterology, Hepatology and Endocrinology bInstitute for Medical Microbiology and Hospital Epidemiology, Hannover cGerman Center for Infection Research (DZIF), partner site Hannover-Braunschweig, Braunschweig, Germany dInstitute for Diagnostic and Interventional Radiology, Hannover Medical School, Hannover.

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http://Insights.ovid.com/crossref?an=00042737-201705000-0000
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http://dx.doi.org/10.1097/MEG.0000000000000837DOI Listing
May 2017

The influence of genetic predisposition and autoimmune hepatitis inducing antigens in disease development.

J Autoimmun 2017 03 11;78:39-45. Epub 2016 Dec 11.

Dept. of Gastroenterology, Hepatology & Endocrinology, Hannover Medical School, Germany; Integrated Research and Treatment Center Transplantation (IFB-Tx), Hannover Medical School, Germany.

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http://dx.doi.org/10.1016/j.jaut.2016.12.001DOI Listing
March 2017

Liver transplantation for critically Ill patients with secondary sclerosing cholangitis: Outcome and complications.

Liver Transpl 2015 Oct;21(10):1295-9

Department of Gastroenterology, Hepatology and Endocrinology, Hannover Medical School, Hannover, Germany.

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http://dx.doi.org/10.1002/lt.24192DOI Listing
October 2015

Isolation of human antigen-specific regulatory T cells with high suppressive function.

Eur J Immunol 2014 Sep 8;44(9):2592-602. Epub 2014 Aug 8.

Department of Gastroenterology, Hepatology & Endocrinology, Hannover Medical School, Hannover, Germany.

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http://dx.doi.org/10.1002/eji.201344381DOI Listing
September 2014

HCV-induced immune responses influence the development of operational tolerance after liver transplantation in humans.

Sci Transl Med 2014 Jun;6(242):242ra81

Liver Unit, Hospital Clinic Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBERehd), University of Barcelona, Barcelona 08036, Spain. Institute of Liver Studies, MRC Centre for Transplantation, King's College London, London SE5 9RS, UK.

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http://dx.doi.org/10.1126/scitranslmed.3008793DOI Listing
June 2014

Intrahepatic regulatory T cells in autoimmune hepatitis are associated with treatment response and depleted with current therapies.

J Hepatol 2014 Nov 2;61(5):1106-14. Epub 2014 Jun 2.

Department of Gastroenterology, Hepatology and Endocrinology, Hannover Medical School, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.jhep.2014.05.034DOI Listing
November 2014

Safety and performance of liver biopsies in liver transplant recipients.

Clin Transplant 2014 May 21;28(5):585-9. Epub 2014 Apr 21.

Department of Radiology, Hannover Medical School, Hannover, Germany.

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http://dx.doi.org/10.1111/ctr.12352DOI Listing
May 2014

In vivo visualization of single native pancreatic islets in the mouse.

Contrast Media Mol Imaging 2013 Nov-Dec;8(6):495-504

High-Field Magnetic Resonance Centre, Max-Planck-Institute for Biological Cybernetics, Tübingen, Germany.

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http://dx.doi.org/10.1002/cmmi.1580DOI Listing
August 2014

Hypercortisolaemia due to ectopic adrenocorticotropic hormone secretion by a nasal paraganglioma: a case report and review of the literature.

BMC Res Notes 2013 Aug 19;6:331. Epub 2013 Aug 19.

Department of Gastroenterology, Hepatology and Endocrinology, Hannover Medical School, Hannover, Germany.

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http://dx.doi.org/10.1186/1756-0500-6-331DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3765299PMC
August 2013

Genetic predisposition and environmental danger signals initiate chronic autoimmune hepatitis driven by CD4+ T cells.

Hepatology 2013 Aug 1;58(2):718-28. Epub 2013 Jul 1.

Department of Gastroenterology, Hepatology & Endocrinology, Hannover Medical School, Hannover, Germany.

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http://dx.doi.org/10.1002/hep.26380DOI Listing
August 2013

Animal models for autoimmune liver disease--what is relevant for immune-mediated liver disease.

Dig Dis 2012 11;30 Suppl 1:2-10. Epub 2012 Oct 11.

Department of Gastroenterology, Hepatology and Endocrinology, Hannover Medical School, Hannover, Germany.

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http://dx.doi.org/10.1159/000341114DOI Listing
May 2013

The benefit of animal models for autoimmune hepatitis.

Best Pract Res Clin Gastroenterol 2011 Dec;25(6):643-51

Medizinische Hochschule Hannover, Dept Gastroenterology, Hepatology und Endocrinology, Carl-Neuberg-Str. 1, 30625 Hannover, Germany.

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http://dx.doi.org/10.1016/j.bpg.2011.10.006DOI Listing
December 2011

Requirements and challenges of a preclinical autoimmune hepatitis mouse model.

Dig Dis 2011 30;29(4):402-10. Epub 2011 Aug 30.

Department of Gastroenterology, Hepatology and Endocrinology, Hannover Medical School, Germany.

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http://dx.doi.org/10.1159/000329804DOI Listing
April 2012

Therapeutic efficacy of polyclonal tregs does not require rapamycin in a low-dose irradiation bone marrow transplantation model.

Transplantation 2011 Aug;92(3):280-8

Division of Transplantation, Department of Surgery, Medical University of Vienna, Vienna, Austria.

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http://dx.doi.org/10.1097/TP.0b013e3182241133DOI Listing
August 2011

Mouse models for experimental autoimmune hepatitis: limits and chances.

Dig Dis 2010 7;28(1):70-9. Epub 2010 May 7.

Department of Gastroenterology, Hepatology and Endocrinology, Hannover Medical School, Hannover, Germany.

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http://dx.doi.org/10.1159/000282067DOI Listing
September 2010

The autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy or autoimmune polyglandular syndrome type 1.

Semin Liver Dis 2009 Aug 12;29(3):307-14. Epub 2009 Aug 12.

Department of Gastroenterology, Hepatology, and Endocrinology, Hannover Medical School, 30625 Hannover, Germany.

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http://dx.doi.org/10.1055/s-0029-1233535DOI Listing
August 2009

New animal models for autoimmune hepatitis.

Semin Liver Dis 2009 Aug 12;29(3):262-72. Epub 2009 Aug 12.

Clinic of the Goethe University Frankfurt am Main, Pharmazentrum Frankfurt/ZAFES, 60590 Frankfurt am Main, Germany.

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http://dx.doi.org/10.1055/s-0029-1233536DOI Listing
August 2009

Long-term beta-adrenergic stimulation leads to downregulation of protein phosphatase inhibitor-1 in the heart.

Eur J Heart Fail 2007 Nov 24;9(11):1077-80. Epub 2007 Oct 24.

Institute of Experimental and Clinical Pharmacology and Toxicology, University Medical Center Hamburg-Eppendorf; Hamburg, Germany.

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http://doi.wiley.com/10.1016/j.ejheart.2007.09.006
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http://dx.doi.org/10.1016/j.ejheart.2007.09.006DOI Listing
November 2007

Making regulatory T cells with defined antigen specificity: role in autoimmunity and cancer.

Immunol Rev 2006 Aug;212:163-9

Harvard Medical School, Dana-Farber Cancer Institute, Boston, MA 02115, USA.

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http://dx.doi.org/10.1111/j.0105-2896.2006.00411.xDOI Listing
August 2006

Instruction of Treg commitment in peripheral T cells is suited to reverse autoimmunity.

Semin Immunol 2006 Apr 13;18(2):89-92. Epub 2006 Feb 13.

Harvard Medical School, Dana-Farber Cancer Institute, 44 Binney Street, Boston, MA 02115, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S104453230600011
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http://dx.doi.org/10.1016/j.smim.2006.01.011DOI Listing
April 2006

Antigen-specific FoxP3-transduced T-cells can control established type 1 diabetes.

Diabetes 2005 Feb 10;54(2):306-10. Epub 2004 Dec 10.

Hannover Medical School, Department of Gastroenterology, Hepatology and Endocrinology, Carl Neuberg Str. 1, 30625 Hannover, Germany.

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http://diabetes.diabetesjournals.org/cgi/doi/10.2337/diabete
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http://dx.doi.org/10.2337/diabetes.54.2.306DOI Listing
February 2005

Recessive tolerance to preproinsulin 2 reduces but does not abolish type 1 diabetes.

Nat Immunol 2004 Oct 19;5(10):1028-35. Epub 2004 Sep 19.

Harvard Medical School, Dana Farber Cancer Institute, 44 Binney Street, Boston, Massachusetts 02115, USA.

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http://www.nature.com/articles/ni1120
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http://dx.doi.org/10.1038/ni1120DOI Listing
October 2004

Ouabain treatment is associated with upregulation of phosphatase inhibitor-1 and Na+/Ca(2+)-exchanger and beta-adrenergic sensitization in rat hearts.

Biochem Biophys Res Commun 2004 May;318(1):219-26

Institute of Experimental and Clinical Pharmacology, University Hospital Eppendorf, Hamburg, Germany.

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http://dx.doi.org/10.1016/j.bbrc.2004.04.015DOI Listing
May 2004

Normal incidence of diabetes in NOD mice tolerant to glutamic acid decarboxylase.

J Exp Med 2003 Jun 9;197(12):1635-44. Epub 2003 Jun 9.

Dana Farber Cancer Institute, Harvard Medical School, Boston, MA 02115, USA.

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http://dx.doi.org/10.1084/jem.20030215DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193961PMC
June 2003

Thymic selection revisited: how essential is it?

Immunol Rev 2003 Feb;191:62-78

Harvard Medical School, Dana-Farber Cancer Institute, Boston, MA 02115, USA.

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http://dx.doi.org/10.1034/j.1600-065x.2003.00010.xDOI Listing
February 2003

Animal models of autoimmune hepatitis.

Authors:
Elmar Jaeckel

Semin Liver Dis 2002 Nov;22(4):325-38

Department of Cancer Immunology & AIDS, Dana-Farber Cancer Institute, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1055/s-2002-35703DOI Listing
November 2002

Viruses and diabetes.

Ann N Y Acad Sci 2002 Apr;958:7-25

Department of Cancer Immunology and AIDS, Dana Farber Cancer Institute, Boston, Massachusetts 02115, USA.

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http://dx.doi.org/10.1111/j.1749-6632.2002.tb02943.xDOI Listing
April 2002