Elliot Israel

Elliot Israel

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Elliot Israel

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Nocturnal bilevel positive airway pressure for the treatment of asthma.

Respir Physiol Neurobiol 2019 Dec 2;274:103355. Epub 2019 Dec 2.

Division of Pulmonary, Critical Care and Sleep Medicine, University of California San Diego, San Diego, CA, United States.

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http://dx.doi.org/10.1016/j.resp.2019.103355DOI Listing
December 2019

Anti-IgE or Anti-IL5: That Is the Question.

J Allergy Clin Immunol Pract 2018 May - Jun;6(3):782-784. Epub 2017 Nov 14.

Rutgers Institute for Translational Medicine and Science, Rutgers Biomedical and Health Sciences, Rutgers University, New Brunswick, NJ. Electronic address:

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http://dx.doi.org/10.1016/j.jaip.2017.10.025DOI Listing
November 2019

The asthma Symptom Free Days Questionnaire: how reliable are patient responses?

J Asthma 2019 Nov 26;56(11):1222-1230. Epub 2018 Oct 26.

University of Colorado School of Medicine , Denver , CO , USA.

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https://www.tandfonline.com/doi/full/10.1080/02770903.2018.1
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http://dx.doi.org/10.1080/02770903.2018.1531990DOI Listing
November 2019

Extrafine Versus Fine Inhaled Corticosteroids in Relation to Asthma Control: A Systematic Review and Meta-Analysis of Observational Real-Life Studies.

J Allergy Clin Immunol Pract 2018 May - Jun;6(3):907-915.e7. Epub 2017 Sep 20.

Observational and Pragmatic Research Institute Pte Ltd, Singapore; Academic Primary Care, Division of Applied Health Sciences, University of Aberdeen, Aberdeen, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/j.jaip.2017.07.032DOI Listing
October 2019

Increased extracellular maspin levels after mechanical compression in vitro or allergen challenge in vivo.

J Allergy Clin Immunol 2019 Oct 19;144(4):1116-1118.e4. Epub 2019 Jun 19.

Molecular and Integrative Physiological Sciences Program, Department of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, Mass. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00916749193080
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http://dx.doi.org/10.1016/j.jaci.2019.06.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6779518PMC
October 2019

Asthma Step-Down Strategies: Perhaps the Patient Should Decide?

J Allergy Clin Immunol Pract 2018 Mar - Apr;6(2):644-645

Harvard Medical School, Pulmonary and Critical Care Division, Brigham & Women's Hospital, Boston, Mass.

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http://dx.doi.org/10.1016/j.jaip.2017.08.026DOI Listing
September 2019

Step-Up Therapy in Black Children and Adults with Poorly Controlled Asthma.

N Engl J Med 2019 09;381(13):1227-1239

From National Jewish Health (M.E.W., R.C., J.T.O.), Denver, and University of Colorado School of Medicine (M.E.W., S.J.S., R.C., F.H., J.T.O.) and Children's Hospital Colorado (S.J.S.), Aurora - all in Colorado; Wake Forest School of Medicine (V.E.O., W.C.M., S.P.P.), Winston-Salem, North Carolina Clinical Research (C.F.L.), Raleigh, and Duke University Medical Center (N.L., L.Q.), Durham - all in North Carolina; Ann and Robert H. Lurie Children's Hospital of Chicago (J.A.P., R.G.R.), University of Illinois at Chicago (J.A.K., H.K.), Rush University Medical Center (J.M.), University of Chicago (E.N., J.S., S. White), and Northwestern University Feinberg School of Medicine (L.J.S.) - all in Chicago; Penn State University (V.C., S.J.K., D.M.), Hershey, and Allegheny General Hospital (D.G.) and University of Pittsburgh Medical Center (S. Wenzel), Pittsburgh - all in Pennsylvania; Nemours Children's Health System, Jacksonville (J.J.L., K.V.B., J.L.), and University of South Florida Morsani College of Medicine, Tampa (J.-C.C.) - both in Florida; University of Arizona Health Sciences, Tucson (E.R.B., M.K., F.M., D.A.M.); Washington University School of Medicine, St. Louis (L.B.B., A.B., M.C.); University of California, San Francisco (UCSF), San Francisco (M.B., M.D.C., S.C.L., D.L.) and UCSF Benioff Children's Hospital, Oakland (M.B., D.L.) - both in California; Brigham and Women's Hospital and Harvard Medical School (J.-C.C., N.G., E.I.) and Boston Children's Hospital (W.P., W.S.) - all in Boston; University Hospitals Rainbow Babies and Children's Hospital, Case Western Reserve University School of Medicine, Cleveland (J.F.C., K.R.); University of Wisconsin-Madison, Madison (L.D., D.J.J., R.F.L., C.A.S.) and Aurora Sinai Medical Center, Milwaukee (L.S.-V.) - both in Wisconsin; Columbia University Irving Medical Center, New York, (E.D.); Emory University, Atlanta (A.M.F.); and University of New Mexico, Albuquerque (H.R.).

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http://dx.doi.org/10.1056/NEJMoa1905560DOI Listing
September 2019

Susceptibility to exacerbations in Black adults with asthma.

J Asthma 2019 Jul 4;56(7):704-710. Epub 2018 Oct 4.

c Brigham and Women's Hospital , Boston , MA , USA.

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http://dx.doi.org/10.1080/02770903.2018.1486855DOI Listing
July 2019

Mometasone or Tiotropium in Mild Asthma with a Low Sputum Eosinophil Level.

N Engl J Med 2019 05 19;380(21):2009-2019. Epub 2019 May 19.

From the Division of Pulmonary and Critical Care Medicine and the Cardiovascular Research Institute (S.C.L., H.A.B., J.V.F., P.G.W.) and the Department of Pediatrics, Epidemiology, and Biostatistics (M.D.C.), University of California, San Francisco, San Francisco; the University of Illinois at Chicago (J.A.K.), the Department of Pediatrics, Rush University Medical Center (J.N.M.), Ann and Robert Lurie Children's Hospital of Chicago (J.A.P.), and Northwestern University, Feinberg School of Medicine (L.S.) - all in Chicago; the Department of Public Health Sciences, Penn State University, Hershey (T.S.K., V.M.C., D.T.M., A.-M.D.), and the University of Pittsburgh Asthma Institute (S.W., F.H.) and Allegheny General Hospital (D.G.), Pittsburgh - all in Pennsylvania; Nemours Children's Hospital, University of Central Florida College of Medicine, Orlando (J.E.L., K.V.B.), and Nemours Children's Health System, Jacksonville (J.E.L., K.V.B.) - both in Florida; the Department of Pediatrics and Medicine, National Jewish Health, Denver (R.C., S.J.S., M.E.W.), and Children's Hospital Colorado, Aurora (R.C., S.J.S., M.E.W.) - both in Colorado; Duke Allergy, Asthma, and Airway Center, Duke University School of Medicine, Durham (N.L., M.K., L.Q.), Wake Forest University School of Medicine, Winston-Salem (A.H., W.M., S.P.P.), and North Carolina Clinical Research, Raleigh (C.L.) - all in North Carolina; the Departments of Pediatrics and Medicine, Washington University in St. Louis School of Medicine, St. Louis (L.B.B., M.C.); Brigham and Women's Hospital and Harvard Medical School (J.C.C., E.I.) and Boston Children's Hospital (W.P.) - all in Boston; Rainbow Babies and Children's Hospital, Cleveland (J.C., R.M., K.R.); the University of Wisconsin, Madison (L.D., D.J., R.F.L., C.A.S.); Columbia University, New York (E.D.); the Department of Pediatrics, Emory University, Atlanta (A.M.F.); and the Arizona Respiratory Center, University of Arizona, Tucson (F.D.M., W.J.M.).

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http://dx.doi.org/10.1056/NEJMoa1814917DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6711475PMC
May 2019

Asthma and Corticosteroid Responses in Childhood and Adult Asthma.

Clin Chest Med 2019 03;40(1):163-177

Division of Allergy and Immunology, Boston Children's Hospital, 300 Longwood Avenue, Boston, MA 02115, USA; Harvard Medical School, 25 Shattuck Street, Boston, MA 02115, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S02725231183012
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http://dx.doi.org/10.1016/j.ccm.2018.10.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6355159PMC
March 2019

What Patients Can Tell Us About Their Asthma.

J Allergy Clin Immunol Pract 2019 Mar;7(3):906-907

Division of Pulmonary and Critical Care Medicine, Division of Rheumatology, Immunology, and Allergy, Brigham and Women's Hospital, Harvard Medical School, Boston, Mass. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S22132198183076
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http://dx.doi.org/10.1016/j.jaip.2018.11.031DOI Listing
March 2019

Biologics, Clinical Context, and the Asthmas.

J Allergy Clin Immunol Pract 2019 May - Jun;7(5):1437-1439

Brigham and Women's Hospital, Boston, Mass.

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http://dx.doi.org/10.1016/j.jaip.2019.03.012DOI Listing
March 2019

Plasma tryptase elevation during aspirin-induced reactions in aspirin-exacerbated respiratory disease.

J Allergy Clin Immunol 2019 02 16;143(2):799-803.e2. Epub 2018 Oct 16.

Brigham and Women's Hospital, Jeff and Penny Vinik Center for Allergic Diseases Research, Division of Rheumatology, Immunology, and Allergy, Building for Transformative Medicine, Boston, Mass; Harvard Medical School, Boston, Mass. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00916749183144
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http://dx.doi.org/10.1016/j.jaci.2018.10.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6519056PMC
February 2019

Refractory airway type 2 inflammation in a large subgroup of asthmatic patients treated with inhaled corticosteroids.

J Allergy Clin Immunol 2019 01 7;143(1):104-113.e14. Epub 2018 Mar 7.

Division of Pulmonary and Critical Care Medicine, Department of Medicine and the Cardiovascular Research Institute, University of California San Francisco, San Francisco, Calif. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2017.12.1009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6128784PMC
January 2019

A trial of type 12 purinergic (P2Y) receptor inhibition with prasugrel identifies a potentially distinct endotype of patients with aspirin-exacerbated respiratory disease.

J Allergy Clin Immunol 2019 01 8;143(1):316-324.e7. Epub 2018 Jun 8.

Department of Medicine, Harvard Medical School, the Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, and the Jeff and Penny Vinik Center, Boston, Mass.

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http://dx.doi.org/10.1016/j.jaci.2018.06.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6286686PMC
January 2019

Flexibility and strength training in asthma: A pilot study.

J Asthma 2018 12 8;55(12):1376-1383. Epub 2018 Feb 8.

a Division of Preventive Medicine, Brigham and Women's Hospital , Harvard Medical School , Boston , MA.

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http://dx.doi.org/10.1080/02770903.2017.1414236DOI Listing
December 2018

A functional splice variant associated with decreased asthma risk abolishes the ability of gasdermin B to induce epithelial cell pyroptosis.

J Allergy Clin Immunol 2018 11 9;142(5):1469-1478.e2. Epub 2018 Jan 9.

Program in Molecular and Integrative Physiological Sciences, Departments of Environmental Health and Genetics & Complex Diseases, Harvard T.H. Chan School of Public Health, Boston, Mass. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2017.11.040DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6037620PMC
November 2018

Harmonizing the Nomenclature for Therapeutic Aerosol Particle Size: A Proposal.

J Aerosol Med Pulm Drug Deliv 2018 04 28;31(2):111-113. Epub 2017 Nov 28.

9 University Paris Descartes (EA2511), Cochin Hospital Group (AP-HP) , Paris, France .

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http://dx.doi.org/10.1089/jamp.2017.1396DOI Listing
April 2018

Food and Drug Administration-mandated Trials of Long-Acting β-Agonist Safety in Asthma. Bang for the Buck?

Am J Respir Crit Care Med 2018 04;197(8):987-990

6 University of California San Diego, San Diego, California.

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http://dx.doi.org/10.1164/rccm.201709-1940PPDOI Listing
April 2018

The IL-33-PIN1-IRAK-M axis is critical for type 2 immunity in IL-33-induced allergic airway inflammation.

Nat Commun 2018 04 23;9(1):1603. Epub 2018 Apr 23.

Division of Translational Therapeutics, Department of Medicine and Cancer Research Institute, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, 02215, USA.

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http://www.nature.com/articles/s41467-018-03886-6
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http://dx.doi.org/10.1038/s41467-018-03886-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5913134PMC
April 2018

Quintupling Inhaled Glucocorticoids to Prevent Childhood Asthma Exacerbations.

N Engl J Med 2018 Mar 3;378(10):891-901. Epub 2018 Mar 3.

From the Department of Pediatrics, University of Wisconsin School of Medicine and Public Health (D.J.J., R.F.L.J.), and the University of Wisconsin-Madison (C.A.S.) - both in Madison; the Department of Pediatrics, Washington University in St. Louis School of Medicine and St. Louis Children's Hospital, St. Louis (L.B.B., A.B.); the Department of Public Health Sciences, Penn State University, Hershey (D.T.M., S.B.), and the University of Pittsburgh Asthma Institute at University of Pittsburgh Medical Center-University of Pittsburgh School of Medicine (F.H.) and the Department of Pediatrics, Allegheny General Hospital (D.A.G.), Pittsburgh - all in Pennsylvania; the Department of Pediatrics, Case Western Reserve University School of Medicine, Rainbow Babies and Children's Hospital, Cleveland (J.F.C., R.E.M., K.R.); the Department of Pediatrics, Emory University, Atlanta (A.M.F.); the Divisions of Respiratory Diseases (J.M.G.) and Allergy-Immunology, Boston Children's Hospital (W.P., W.J.S., S.N.B.), Harvard Medical School, and Brigham and Women's Hospital, Harvard Medical School (E.I.) - all in Boston; the Arizona Respiratory Center, University of Arizona, Tucson (W.J.M., F.D.M.); Wake Forest University School of Medicine, Winston-Salem, NC (S.P.P.); the Departments of Pediatrics (M.D.C., N.L.), Epidemiology (M.D.C.), Biostatistics (M.D.C.), and Medicine (S.C.L.), University of California, San Francisco (UCSF), and UCSF Benioff Children's Hospital (M.D.C.) - both in San Francisco; Ann and Robert H. Lurie Children's Hospital of Chicago (J.A.P., R.G.R.), University of Illinois at Chicago (J.A.K., H.V.K.), and the Department of Pediatrics, Stroger Hospital of Cook County, Rush University Medical Center (J.N.M.) - all in Chicago; UCSF Benioff Children's Hospital Oakland, Oakland (M.B., D.L., J.M.); Nemours Children's Health System, Jacksonville (K.B., J.J.L.), and Nemours Children's Hospital, University of Central Florida College of Medicine, Orlando (J.E.L.) - both in Florida; the Department of Pediatrics, National Jewish Health, Denver (R.C., J.T.O.); and the Department of Pediatrics, University of New Mexico, Albuquerque (H.H.R.).

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http://www.nejm.org/doi/10.1056/NEJMoa1710988
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http://dx.doi.org/10.1056/NEJMoa1710988DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5972517PMC
March 2018

Income is an independent risk factor for worse asthma outcomes.

J Allergy Clin Immunol 2018 02 20;141(2):754-760.e3. Epub 2017 May 20.

Department of Medicine, Brigham and Women's Hospital, Boston, Mass; the Division of Allergy and Immunology, Boston Children's Hospital, Boston, Mass. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2017.04.036DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5696111PMC
February 2018

Internet-Based Monitoring in the Severe Asthma Research Program Identifies a Subgroup of Patients With Labile Asthma Control.

Chest 2018 02 26;153(2):378-386. Epub 2017 Oct 26.

Division of Pulmonary and Critical Care Medicine, Department of Medicine and the Cardiovascular Research Institute, University of California San Francisco, San Francisco, CA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00123692173291
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http://dx.doi.org/10.1016/j.chest.2017.10.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5815875PMC
February 2018

Real-Life Outcomes for Patients with Asthma Prescribed Spacers for Use with Either Extrafine- or Fine-Particle Inhaled Corticosteroids.

J Allergy Clin Immunol Pract 2017 Jul - Aug;5(4):1040-1049.e4. Epub 2017 Jan 18.

Observational and Pragmatic Research Institute Pte Ltd, Singapore; Academic Primary Care, Division of Applied Health Sciences, University of Aberdeen, Aberdeen, United Kingdom. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S22132198163058
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http://dx.doi.org/10.1016/j.jaip.2016.11.026DOI Listing
January 2018

Severe and Difficult-to-Treat Asthma in Adults.

N Engl J Med 2017 Sep;377(10):965-976

From the Pulmonary and Critical Care Medicine Division-Division of Rheumatology, Immunology, and Allergy, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston (E.I.); and the Clinical Management Group and Centre for Research Excellence in Severe Asthma, Woolcock Institute of Medical Research, University of Sydney, Sydney (H.K.R.).

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http://dx.doi.org/10.1056/NEJMra1608969DOI Listing
September 2017

Novel Treatments for Airway Disease.

N Engl J Med 2017 08;377(6):597

Brigham and Women’s Hospital, Boston, MA

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http://www.nejm.org/doi/10.1056/NEJMc1708004
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http://dx.doi.org/10.1056/NEJMc1708004DOI Listing
August 2017

KIT Inhibition by Imatinib in Patients with Severe Refractory Asthma.

N Engl J Med 2017 05;376(20):1911-1920

From Brigham and Women's Hospital, Harvard Medical School, Boston (K.N.C., H.R.K., J.C., J.L., A.C.-T., D.G., T.M.L., J.A.B., E.I.), and Novartis Institutes for BioMedical Research, Cambridge (S.K.) - both in Massachusetts; Washington University, St. Louis (M.C.); University of Wisconsin, Madison (N.J.); Columbia University Medical Center, New York (E.D.); Cleveland Clinic, Cleveland (S.E.); University of Alabama at Birmingham, Birmingham (J.L.T.); Temple University, Philadelphia (K.S.), and Pennsylvania State University, Hershey (V.M.C.) - both in Pennsylvania; and National Jewish Health, Denver (M.E.W.).

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http://dx.doi.org/10.1056/NEJMoa1613125DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5568669PMC
May 2017

Association Between Insomnia and Asthma Burden in the Severe Asthma Research Program (SARP) III.

Chest 2016 Dec 6;150(6):1242-1250. Epub 2016 Oct 6.

Division of Pulmonary, Allergy, and Critical Care Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA.

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http://dx.doi.org/10.1016/j.chest.2016.09.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5310183PMC
December 2016

Alternative Macrophage Activation Is Increased in Asthma.

Am J Respir Cell Mol Biol 2016 Oct;55(4):467-475

1 Pulmonary and Critical Care Medicine Division, Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts.

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http://dx.doi.org/10.1165/rcmb.2015-0295OCDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5070104PMC
October 2016

Insulin resistance modifies the association between obesity and current asthma in adults.

Eur Respir J 2016 08 21;48(2):403-10. Epub 2016 Apr 21.

Division of Rheumatology, Immunology, and Allergy, Brigham and Women's Hospital, Boston, MA, USA Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Boston, MA, USA

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http://dx.doi.org/10.1183/13993003.00246-2016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5815169PMC
August 2016

Acetaminophen versus Ibuprofen in Young Children with Mild Persistent Asthma.

N Engl J Med 2016 Aug;375(7):619-30

From the Divisions of Allergy and Immunology (W.J.S., S.N.B., W.P.) and Respiratory Diseases (J.M.G.), Boston Children's Hospital and Harvard Medical School, and the Division of Allergy and Pulmonary Medicine, Brigham and Women's Hospital and Harvard Medical School (E.I.) - all in Boston; the Departments of Public Health Sciences (D.T.M., S.J.B.) and Pediatrics (I.M.P.), Penn State College of Medicine, Hershey, and the University of Pittsburgh Asthma Institute at University of Pittsburgh Medical Center (F.H.) and the Department of Pediatrics, Allegheny General Hospital (D.A.G.), Pittsburgh - all in Pennsylvania; Stroger Hospital of Cook County and Department of Pediatrics, Rush University Medical Center (J.N.M.), Ann and Robert H. Lurie Children's Hospital of Chicago (J.A.P., R.G.R.), and University of Illinois at Chicago (H.V.K.) - all in Chicago; the Breathing Institute, Children's Hospital Colorado (S.J.S.), and the Departments of Pediatrics (S.J.S.) and Medicine (M.E.W.), University of Colorado School of Medicine, Aurora, and the Department of Pediatrics (R.C., J.T.O.) and Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine (M.E.W.), National Jewish Health, Denver - both in Colorado; the Department of Pediatrics, Emory University, Atlanta (A.M.F.); the Section of Allergy, Immunology, and Rheumatology, Department of Pediatrics, University of Wisconsin School of Medicine and Public Health (D.J.J., R.F.L.) and the School of Pharmacy, University of Wisconsin-Madison (C.A.S.) - both in Madison; Washington University School of Medicine in St. Louis and the Department of Pediatrics, St. Louis Children's Hospital (L.B.B., A.B.) - both in St. Louis; the Departments of Pediatrics (M.D.C.) and Medicine (S.C.L.) and the Airway Clinical Research Center (N.L.), University of California, San Francisco, San Francisco, Benioff Children's Hospital Oakland, Oakland (M.B., J.M.), and Olive View UCLA Medical Center and Department of Pediatrics, David Geff

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5085065PMC
http://dx.doi.org/10.1056/NEJMoa1515990DOI Listing
August 2016

Small-particle Inhaled Corticosteroid as First-line or Step-up Controller Therapy in Childhood Asthma.

J Allergy Clin Immunol Pract 2015 Sep-Oct;3(5):721-31.e16. Epub 2015 May 29.

Research in Real Life, Ltd, Cambridge, UK; Academic Primary Care, University of Aberdeen, Aberdeen, UK. Electronic address:

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http://dx.doi.org/10.1016/j.jaip.2015.04.012DOI Listing
July 2016

Vitamin D3 treatment of vitamin D-insufficient asthmatic patients does not alter immune cell function.

J Allergy Clin Immunol 2016 07 10;138(1):286-289.e9. Epub 2016 Feb 10.

Department of Internal Medicine, Washington University School of Medicine, St Louis, Mo; Department of Pathology and Immunology, Washington University School of Medicine, St Louis, Mo. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2015.11.030DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4931954PMC
July 2016

Thymic stromal lymphopoietin controls prostaglandin D2 generation in patients with aspirin-exacerbated respiratory disease.

J Allergy Clin Immunol 2016 05 12;137(5):1566-1576.e5. Epub 2015 Dec 12.

Department of Medicine, Harvard Medical School, Boston, Mass; Division of Rheumatology, Immunology, and Allergy, Brigham and Women's Hospital, Boston, Mass.

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http://dx.doi.org/10.1016/j.jaci.2015.10.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4860132PMC
May 2016

Asthma Is More Severe in Older Adults.

PLoS One 2015 22;10(7):e0133490. Epub 2015 Jul 22.

Respiratory Institute, Cleveland Clinic, Cleveland, Ohio, United States of America; Department of Pathobiology, Cleveland Clinic, Cleveland, Ohio, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0133490PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4511639PMC
April 2016

Update on reslizumab for eosinophilic asthma.

Expert Opin Biol Ther 2015 ;15(10):1531-9

d 4 Harvard Medical School. Director of Clinical Research, Division of Pulmonary Medicine, Brigham and Women's Hospital , 75 Francis st, Boston, MA 02115, USA +1 61 77 32 81 10 ; +1 61 77 32 74 21 ;

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http://dx.doi.org/10.1517/14712598.2015.1090972DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5161345PMC
April 2016

IL-13 Augments Compressive Stress-Induced Tissue Factor Expression in Human Airway Epithelial Cells.

Am J Respir Cell Mol Biol 2016 Apr;54(4):524-31

1 Molecular and Integrative Physiological Sciences Program, Department of Environmental Health, Harvard T. H. Chan School of Public Health, Boston, Massachusetts.

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http://dx.doi.org/10.1165/rcmb.2015-0252OCDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4821058PMC
April 2016

Early Administration of Azithromycin and Prevention of Severe Lower Respiratory Tract Illnesses in Preschool Children With a History of Such Illnesses: A Randomized Clinical Trial.

JAMA 2015 Nov;314(19):2034-2044

Department of Pediatrics, Washington University in St Louis School of Medicine, St Louis, Missouri (Bacharier, Beigelman, Castro); Cincinnati Children's Hospital and Medical Center, Cincinnati, Ohio (Guilbert); Department of Public Health Sciences, Pennsylvania State University, Hershey (Mauger, Boehmer); Department of Pediatrics, Emory University, Atlanta, Georgia (Fitzpatrick); Pediatrics Section of Allergy, Immunology, and Rheumatology, University of Wisconsin School of Medicine and Public Health, Madison (Jackson); Division of Allergy/Immunology, Boston Children's Hospital, Boston, Massachusetts (Baxi, Phipatanakul, Sheehan); Benioff Children's Hospital, Oakland, California (Benson, Meade); Department of Pathology and Immunology, Washington University in St Louis School of Medicine, St Louis, Missouri (Burnham); University of California, San Francisco, Medicine, San Francisco (Cabana, Lazarus); Rainbow Babies and Children's Hospital, Cleveland, Ohio (Chmiel, Ross); Department of Pediatrics, National Jewish Health, Denver, Colorado (Covar, Olin); University of Arizona, Arizona Respiratory Center, Tucson (Daines, Morgan); Division of Respiratory Diseases, Boston Children's Hospital, Boston, Massachusetts (Gaffin); Department of Pediatrics, Allegheny General Hospital, Pittsburgh, Pennsylvania (Gentile); The University of Pittsburgh Asthma Institute, Pittsburgh, Pennsylvania (Holguin); Brigham and Women's Hospital, Boston, Massachusetts (Israel); Department of Pediatrics, University of New Mexico School of Medicine, Albuquerque, New Mexico (Kelly); Department of Pediatrics, University of Wisconsin School of Medicine and Public Health, Madison (Lemanske); Airway Clinical Research Center, University of California, San Francisco, San Francisco, California (Ly); Stroger Hospital of Cook County Pediatric Services, Chicago, Illinois (Moy); Wake Forest University School of Medicine, Winston-Salem, North Carolina (Peters); Ann and Robert H Lurie Children's Hospital of Chicago, Chicago, Illinois (Pongracic); Department of Pediatrics/Pulmonary, University of New Mexico, Albuquerque (Raissy); University of Wisconsin-Madison, Madison (Sorkness); The Breathing Institute, Children's Hospital Colorado, Denver (Szefler); University of Virginia School of Medicine, Charlottesville (Teague); Department of Pediatrics, San Francisco General Hospital, San Francisco, California (Thyne); Arizona Respiratory Center, University of Arizona, Tucson, Arizona (Martinez).

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4757487PMC
November 2015

Precision Medicine. Personalizing Guidelines to the Provider as Well as the Patient: Making the Juice Worth the Squeeze.

Am J Respir Crit Care Med 2015 Jun;191(12):1345-6

2 Division of Pulmonary and Critical Care Medicine Brigham and Women's Hospital Boston, Massachusetts.

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June 2015

Comparing the effectiveness of small-particle versus large-particle inhaled corticosteroid in COPD.

Int J Chron Obstruct Pulmon Dis 2014 17;9:1163-86. Epub 2014 Oct 17.

Research in Real Life, Ltd, Cambridge, UK ; Academic Primary Care, Division of Applied Health Sciences, University of Aberdeen, Aberdeen, UK.

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http://dx.doi.org/10.2147/COPD.S68289DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4207569PMC
February 2015

Unsupervised phenotyping of Severe Asthma Research Program participants using expanded lung data.

J Allergy Clin Immunol 2014 May 28;133(5):1280-8. Epub 2014 Feb 28.

National Jewish Medical and Research Center, University of Colorado Health Sciences Center, Denver, Colo; Asthma Institute, Division of Pulmonary, Allergy and Critical Care Medicine, University of Pittsburgh, Pittsburgh, Pa. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2013.11.042DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4038417PMC
May 2014

Severe asthma: pragmatic clinical lumping and time for investigational splitting.

Am J Respir Crit Care Med 2014 Mar;189(6):619-20

1 Pulmonary and Critical Care Medicine, Partners Asthma Center Brigham and Women's Hospital Boston, Massachusetts.

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March 2014

Reply: "The intrinsic bias of generalizations" and "Far from 'disappointing'".

Am J Respir Crit Care Med 2014 Feb;189(3):361-2

1 Brigham and Women's Hospital Boston, Massachusetts.

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February 2014

Effect of ADRB2 polymorphisms on the efficacy of salmeterol and tiotropium in preventing COPD exacerbations: a prespecified substudy of the POET-COPD trial.

Lancet Respir Med 2014 Jan 5;2(1):44-53. Epub 2013 Dec 5.

Department of Medicine, Pulmonary and Critical Care Medicine, University Medical Centre Giessen and Marburg, Philipps-Universität Marburg, Germany.

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January 2014