Ellen C Zwarthoff

Ellen C Zwarthoff

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Ellen C Zwarthoff

Ellen C Zwarthoff

Publications by authors named "Ellen C Zwarthoff"

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Molecular and clinical heterogeneity within the luminal subtype.

Nat Rev Urol 2019 Dec 3. Epub 2019 Dec 3.

Department of Pathology, Erasmus MC University Medical Center, Rotterdam, Netherlands.

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http://dx.doi.org/10.1038/s41585-019-0262-7DOI Listing
December 2019

New horizons in bladder cancer research.

Urol Oncol 2019 Mar 7. Epub 2019 Mar 7.

Department of Urology, Friedrich-Alexander University, Erlangen, Germany; MVZ Urologie 24, Nuremberg, Germany. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S10781439183050
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http://dx.doi.org/10.1016/j.urolonc.2018.12.014DOI Listing
March 2019

Analysis of Point Mutations in Clinical Samples of Urothelial Carcinoma.

Methods Mol Biol 2018 ;1655:19-28

Department of Pathology, Erasmus MC, PO Box2040, 3000 CA, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1007/978-1-4939-7234-0_2DOI Listing
May 2018

Development and Validation of Urine-based Peptide Biomarker Panels for Detecting Bladder Cancer in a Multi-center Study.

Clin Cancer Res 2016 Aug 29;22(16):4077-86. Epub 2016 Mar 29.

Laboratory of Biology, Department of Basic Medical Sciences, University of Athens School of Medicine, Athens, Greece. Laboratory of Cell and Gene Therapy, Biomedical Research Foundation of the Academy of Athens, Athens, Greece.

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http://dx.doi.org/10.1158/1078-0432.CCR-15-2715DOI Listing
August 2016

Evaluation of an Epigenetic Profile for the Detection of Bladder Cancer in Patients with Hematuria.

J Urol 2016 Mar 29;195(3):601-7. Epub 2015 Aug 29.

MDxHealth, Inc., Irvine, California; Laboratory of Bioinformatics and Computational Genomics, Ghent University, Ghent, Belgium. Electronic address:

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http://dx.doi.org/10.1016/j.juro.2015.08.085DOI Listing
March 2016

Predicting Response to Intravesical Bacillus Calmette-Guérin Immunotherapy: Are We Moving Forward?

Eur Urol 2016 Feb 21;69(2):201-2. Epub 2015 Jul 21.

Department of Pathology, Erasmus Medical Centre Rotterdam, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.eururo.2015.07.010DOI Listing
February 2016

Limited Funds for Bladder Cancer Research and What Can We Do About It.

Bladder Cancer 2016 Jan 28;2(1):49-51. Epub 2016 Jan 28.

Erasmus MC Cancer Institute , Departments of Urology and Pathology, Rotterdam, The Netherlands.

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http://dx.doi.org/10.3233/BLC-150042DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4927910PMC
January 2016

Targeted therapies in bladder cancer: an overview of in vivo research.

Nat Rev Urol 2015 Dec 22;12(12):681-94. Epub 2015 Sep 22.

Department of Pathology, Erasmus MC, PO Box 2040, 3000 CA, Rotterdam, Netherlands.

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http://dx.doi.org/10.1038/nrurol.2015.231DOI Listing
December 2015

Editorial Comment.

Urology 2015 Dec;86(6):1190-1

Department of Pathology, Erasmus MC Cancer Institute, Rotterdam, Netherlands.

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http://dx.doi.org/10.1016/j.urology.2015.07.037DOI Listing
December 2015

Molecular and clinical support for a four-tiered grading system for bladder cancer based on the WHO 1973 and 2004 classifications.

Mod Pathol 2015 May 28;28(5):695-705. Epub 2014 Nov 28.

1] Department of Pathology, Josephine Nefkens Institute, Erasmus MC, Rotterdam, The Netherlands [2] Department of Surgical Pathology, University Health Network, Toronto, ON, Canada.

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http://dx.doi.org/10.1038/modpathol.2014.154DOI Listing
May 2015

Epidermal nevus in association with some uncommon manifestations.

Acta Dermatovenerol Croat 2013 ;21(4):268-70

Nima Rezaei, MD, PhD, Children's Medical Center Hospital, Dr. Qarib St., Keshavarz Blvd., Tehran 14194, Iran;

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April 2015

Intratumour heterogeneity in urologic cancers: from molecular evidence to clinical implications.

Eur Urol 2015 Apr 2;67(4):729-37. Epub 2014 May 2.

CR-UK London Research Institute, London, UK; University College London Cancer Institute, London, UK. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S03022838140039
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http://dx.doi.org/10.1016/j.eururo.2014.04.014DOI Listing
April 2015

TERT promoter mutations and BRAF mutations are rare in sporadic, and TERT promoter mutations are absent in NF1-related malignant peripheral nerve sheath tumors.

J Neurooncol 2014 Nov 18;120(2):267-72. Epub 2014 Jul 18.

Department of Pathology, Erasmus MC Cancer Institute, University Medical Center Rotterdam, PO-Box 2040, 3000 CA, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1007/s11060-014-1553-8DOI Listing
November 2014

Telomerase reverse transcriptase promoter mutations in tumors originating from the adrenal gland and extra-adrenal paraganglia.

Endocr Relat Cancer 2014 Aug 20;21(4):653-61. Epub 2014 Jun 20.

Department of PathologyJosephine Nefkens Institute, Erasmus MC, Rotterdam, The NetherlandsDepartment of Pediatric Oncology-HematologyErasmus MC-Sophia Children's Hospital, Rotterdam, The NetherlandsSector of EndocrinologyDepartment of Internal Medicine, Erasmus MC, Rotterdam, The NetherlandsCancer Biology and Metabolism GroupInstitute of Genetics and Molecular Medicine, Edinburgh Cancer Research UK Centre, University of Edinburgh, Edinburgh, UKDepartment of Medical GeneticsUniversity of Cambridge, Cambridge, UKDepartment of SurgeryErasmus MC, Rotterdam, The NetherlandsDivision of EndocrinologyDepartment of Medicine, Radboud University Nijmegen Medical Center, Nijmegen, The NetherlandsDepartment of Medical OncologyErasmus MC, Rotterdam, The NetherlandsDepartment of PathologyReinier de Graaf Hospital, Delft, The Netherlands

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http://erc.endocrinology-journals.org/content/early/2014/06/
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http://erc.endocrinology-journals.org/cgi/doi/10.1530/ERC-13
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http://dx.doi.org/10.1530/ERC-13-0429DOI Listing
August 2014

Prevalence and implications of TERT promoter mutation in uveal and conjunctival melanoma and in benign and premalignant conjunctival melanocytic lesions.

Invest Ophthalmol Vis Sci 2014 Aug 26;55(9):6024-30. Epub 2014 Aug 26.

Department of Pathology, Erasmus MC Cancer Institute, University Medical Center Rotterdam, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1167/iovs.14-14901DOI Listing
August 2014

HRAS mutations in bladder cancer at an early age and the possible association with the Costello Syndrome.

Eur J Hum Genet 2014 Jun 30;22(6):837-9. Epub 2013 Oct 30.

Department of Pathology, Erasmus Medical Centre, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1038/ejhg.2013.251DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4023225PMC
June 2014

DNA methylation-based biomarkers in bladder cancer.

Nat Rev Urol 2013 Jun 30;10(6):327-35. Epub 2013 Apr 30.

Department of Pathology, Erasmus MC, P. O. Box 2040, 3000 CA Rotterdam, The Netherlands.

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http://dx.doi.org/10.1038/nrurol.2013.89DOI Listing
June 2013

Down-staging (

Virchows Arch 2012 Aug 10;461(2):149-56. Epub 2012 Jul 10.

Department of Pathology, Josephine Nefkens Institute, Erasmus MC, PO Box 2040, 3000 CA, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1007/s00428-012-1277-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3421107PMC
August 2012

Markers predicting response to bacillus Calmette-Guérin immunotherapy in high-risk bladder cancer patients: a systematic review.

Eur Urol 2012 Jan 6;61(1):128-45. Epub 2011 Oct 6.

Department of Pathology, Erasmus Medical Centre Rotterdam, The Netherlands.

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http://dx.doi.org/10.1016/j.eururo.2011.09.026DOI Listing
January 2012

Optimization of nonmuscle invasive bladder cancer recurrence detection using a urine based FGFR3 mutation assay.

J Urol 2011 Aug 17;186(2):707-12. Epub 2011 Jun 17.

Department of Pathology, Erasmus Medical Center, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1016/j.juro.2011.03.141DOI Listing
August 2011

No evidence of FGFR3 mutations in prostate cancer.

Prostate 2011 May 18;71(6):637-41. Epub 2010 Oct 18.

Department of Pathology, Erasmus MC, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1002/pros.21279DOI Listing
May 2011

Feasibility study of screening for bladder cancer with urinary molecular markers (the BLU-P project).

Urol Oncol 2010 Nov-Dec;28(6):686-90

Erasmus Medical Centre, Department of Urology and Pathology, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1016/j.urolonc.2009.12.002DOI Listing
February 2011

Bladder cancer: novel molecular characteristics, diagnostic, and therapeutic implications.

Urol Oncol 2010 Jan-Feb;28(1):91-6

Department of Pathology, Josephine Nefkens Institute, Rotterdam, The Netherlands.

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https://linkinghub.elsevier.com/retrieve/pii/S10781439090018
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http://dx.doi.org/10.1016/j.urolonc.2009.06.007DOI Listing
May 2010

Sexual function of patients under surveillance for bladder cancer.

BJU Int 2009 Jul 14;104(1):35-40. Epub 2009 Jan 14.

Department of Pathology, Erasmus MC Rotterdam, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1111/j.1464-410X.2008.08333.xDOI Listing
July 2009

Meningioma 1 is required for appropriate osteoblast proliferation, motility, differentiation, and function.

J Biol Chem 2009 Jul 22;284(27):18174-83. Epub 2009 Apr 22.

Department of Pharmacology, Case Western Reserve University, Cleveland, Ohio 44106, USA.

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http://dx.doi.org/10.1074/jbc.M109.001354DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2709374PMC
July 2009

A SNaPshot assay for the rapid and simple detection of four common hotspot codon mutations in the PIK3CA gene.

BMC Res Notes 2009 Apr 29;2:66. Epub 2009 Apr 29.

Cancer Research UK Clinical Centre, Leeds Institute of Molecular Medicine, St James's University Hospital, Leeds, UK.

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http://bmcresnotes.biomedcentral.com/articles/10.1186/1756-0
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http://dx.doi.org/10.1186/1756-0500-2-66DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2683860PMC
April 2009

FGFR3 mutations indicate better survival in invasive upper urinary tract and bladder tumours.

Eur Urol 2009 Mar 13;55(3):650-7. Epub 2008 Jun 13.

Department of Pathology, Josephine Nefkens Institute, Erasmus MC, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1016/j.eururo.2008.06.013DOI Listing
March 2009

Bladder cancer biomarkers and their role in surveillance and screening.

Int J Urol 2009 Jan;16(1):23-30

Department of Pathology, Josephine Nefkens Institute, Erasmus MC, CA, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1111/j.1442-2042.2008.02174.xDOI Listing
January 2009

The Mn1 transcription factor acts upstream of Tbx22 and preferentially regulates posterior palate growth in mice.

Development 2008 Dec 23;135(23):3959-68. Epub 2008 Oct 23.

Department of Biomedical Genetics and Center for Oral Biology, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA.

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http://dx.doi.org/10.1242/dev.025304DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2586179PMC
December 2008

Detection of tumours of the urinary tract in voided urine.

Scand J Urol Nephrol Suppl 2008 Sep(218):147-53

Department of Pathology, Erasmus MC, Rotterdam, The Netherlands.

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http://www.tandfonline.com/doi/full/10.1080/0300888080228395
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http://dx.doi.org/10.1080/03008880802283953DOI Listing
September 2008

Patients' perceived burden of cystoscopic and urinary surveillance of bladder cancer: a randomized comparison.

BJU Int 2008 May 20;101(9):1106-10. Epub 2007 Sep 20.

Department of Pathology, Erasmus MC/University Medical Center, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1111/j.1464-410X.2007.07224.xDOI Listing
May 2008

[Correlation of FGFR3 mutations and chromosomal alterations in bladder cancer].

Verh Dtsch Ges Pathol 2006 ;90:151-8

Klinik für Urologie, Universität, Jena.

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October 2007

FGFR3 mutations in seborrheic keratoses are already present in flat lesions and associated with age and localization.

Mod Pathol 2007 Aug 22;20(8):895-903. Epub 2007 Jun 22.

Department of Dermatology, University of Regensburg, Regensburg, Germany.

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http://dx.doi.org/10.1038/modpathol.3800837DOI Listing
August 2007

The MN1 oncoprotein activates transcription of the IGFBP5 promoter through a CACCC-rich consensus sequence.

J Mol Endocrinol 2007 Feb;38(1-2):113-25

Department of Pathology, Erasmus MC-Josephine Nefkens Institute, PO Box 2040, 3000 CA Rotterdam, The Netherlands.

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http://dx.doi.org/10.1677/jme.1.02110DOI Listing
February 2007

High frequency of FGFR3 mutations in adenoid seborrheic keratoses.

J Invest Dermatol 2006 Nov 15;126(11):2404-7. Epub 2006 Jun 15.

Department of Dermatology, University of Regensburg, Regensburg, Germany.

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https://linkinghub.elsevier.com/retrieve/pii/S0022202X153268
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http://dx.doi.org/10.1038/sj.jid.5700422DOI Listing
November 2006

Lack of genetic and epigenetic changes in meningiomas without NF2 loss.

J Pathol 2006 Mar;208(4):564-73

Department of Pathology, Josephine Nefkens Institute, Erasmus MC, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1002/path.1909DOI Listing
March 2006

Chromosomal instability in meningiomas.

J Neuropathol Exp Neurol 2005 Apr;64(4):312-22

Department of Pathology, Erasmus MC, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1093/jnen/64.4.312DOI Listing
April 2005

The RAS-BRAF kinase pathway is not involved in uveal melanoma.

Melanoma Res 2004 Jun;14(3):203-5

Departments of Clinical Genetics; Ophthalmology; Pathology, Erasmus MC, PO Box 1738, 3000 DR Rotterdam, The Netherlands.

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http://dx.doi.org/10.1097/01.cmr.0000130006.46885.a0DOI Listing
June 2004