Elizabeth Kwong

Elizabeth Kwong

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Elizabeth Kwong

Elizabeth Kwong

Publications by authors named "Elizabeth Kwong"

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Advancing drug discovery: a pharmaceutics perspective.

Authors:
Elizabeth Kwong

J Pharm Sci 2015 Mar 5;104(3):865-71. Epub 2014 Dec 5.

Kwong Eureka Solutions, Quebec, Canada.

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http://dx.doi.org/10.1002/jps.24294DOI Listing
March 2015

Mechanism of amorphous itraconazole stabilization in polymer solid dispersions: role of molecular mobility.

Mol Pharm 2014 Nov 17;11(11):4228-37. Epub 2014 Oct 17.

Department of Pharmaceutics, University of Minnesota , Minneapolis, Minnesota 55455, United States.

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http://dx.doi.org/10.1021/mp5004515DOI Listing
November 2014

Acute adverse events from over-the-counter Chinese herbal medicines: a population-based survey of Hong Kong Chinese.

BMC Complement Altern Med 2013 Nov 27;13:336. Epub 2013 Nov 27.

School of Public Health and Primary Care, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong.

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http://dx.doi.org/10.1186/1472-6882-13-336DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4222756PMC
November 2013

Correlation between molecular mobility and physical stability of amorphous itraconazole.

Mol Pharm 2013 Feb 8;10(2):694-700. Epub 2013 Jan 8.

Department of Pharmaceutics, University of Minnesota, Minneapolis, Minnesota 55455, United States.

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http://dx.doi.org/10.1021/mp300487uDOI Listing
February 2013

Identification of suitable formulations for high dose oral studies in rats using in vitro solubility measurements, the maximum absorbable dose model, and historical data sets.

Mol Pharm 2012 May 27;9(5):1163-74. Epub 2012 Mar 27.

Basic Pharmaceutical Sciences, Merck Research Laboratories, Merck & Co, West Point, Pennsylvania 19486, United States.

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http://dx.doi.org/10.1021/mp200452rDOI Listing
May 2012

Strategies for bringing drug delivery tools into discovery.

Int J Pharm 2011 Jun 21;412(1-2):1-7. Epub 2011 Mar 21.

Basic Pharmaceutical Sciences, Merck Research Laboratories, Merck & Co., Inc., Rahway, NJ 07065, USA.

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http://dx.doi.org/10.1016/j.ijpharm.2011.03.024DOI Listing
June 2011

ESI-MS quantitation of iron as its 4-(2-pyridylazo)resorcinol (PAR) complex: application to pharmaceutical tablets containing iron oxide pigment.

J Mass Spectrom 2011 May;46(5):508-16

Department of Chemistry and Biochemistry, Concordia University, 7141 Sherbrooke Street West, Montreal, QC, H4B 1R6 Canada.

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http://dx.doi.org/10.1002/jms.1919DOI Listing
May 2011

Kinetics and mechanism of S-nitrosothiol acid-catalyzed hydrolysis: sulfur activation promotes facile NO+ release.

J Phys Chem B 2011 Mar 8;115(12):3112-26. Epub 2011 Mar 8.

Department of Chemistry and Biochemistry, Concordia University, Montreal, Québec, Canada.

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http://pubs.acs.org/doi/abs/10.1021/jp1035597
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http://dx.doi.org/10.1021/jp1035597DOI Listing
March 2011

Strategies at the interface of drug discovery and development: early optimization of the solid state phase and preclinical toxicology formulation for potential drug candidates.

J Med Chem 2010 Aug;53(16):5897-905

Basic Pharmaceutical Sciences, Merck Research Laboratories, Merck & Co., Inc., West Point, Pennsylvania 19486, USA.

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http://dx.doi.org/10.1021/jm1002638DOI Listing
August 2010

Translymphatic chemotherapy by intrapleural placement of gelatin sponge containing biodegradable Paclitaxel colloids controls lymphatic metastasis in lung cancer.

Cancer Res 2009 Feb 27;69(3):1174-81. Epub 2009 Jan 27.

Department of Pharmaceutical Science, Faculty of Medicine, Institute of Medical Science, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1158/0008-5472.CAN-08-1753DOI Listing
February 2009

Development of a discriminating in vitro dissolution method for a poorly soluble NO-donating selective cyclooxygenase-2 inhibitor.

J Pharm Biomed Anal 2008 May 23;47(1):16-22. Epub 2007 Dec 23.

Drug Metabolism and Pharmacokinetics, Merck Frosst Center for Therapeutic Research, 16711 Trans Canada Highway, Kirkland, Quebec, Canada H9H 3L1.

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http://linkinghub.elsevier.com/retrieve/pii/S073170850700764
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http://dx.doi.org/10.1016/j.jpba.2007.12.025DOI Listing
May 2008

Characterization of tablet film coatings using a laser-induced breakdown spectroscopic technique.

AAPS PharmSciTech 2007 Dec 14;8(4):E103. Epub 2007 Dec 14.

Merck Frosst Canada Ltd, Pharmaceutical Research and Development, 16711 TransCanada Highway, Kirkland, QC, Canada.

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http://dx.doi.org/10.1208/pt0804103DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2750356PMC
December 2007

A rapid and sensitive method for the quantitation of montelukast in sheep plasma using liquid chromatography/tandem mass spectrometry.

J Chromatogr B Analyt Technol Biomed Life Sci 2007 Oct 7;858(1-2):282-6. Epub 2007 Aug 7.

Pharmaceutical Research and Development, Merck Frosst Center for Therapeutic Research, 16711 Trans Canada Hwy., Kirkland, Quebec, Canada H9H 3L1.

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http://dx.doi.org/10.1016/j.jchromb.2007.08.003DOI Listing
October 2007

A novel trans-lymphatic drug delivery system: implantable gelatin sponge impregnated with PLGA-paclitaxel microspheres.

Biomaterials 2007 Jul 24;28(21):3236-44. Epub 2007 Mar 24.

Institute of Medical Science and Department of Surgery, Faculty of Medicine, University of Toronto, Toronto, Ont., Canada.

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http://dx.doi.org/10.1016/j.biomaterials.2007.03.022DOI Listing
July 2007

The effects of physical parameters on laser-induced breakdown spectroscopy analysis of intact tablets.

AAPS PharmSciTech 2005 Oct 6;6(2):E253-61. Epub 2005 Oct 6.

Merck Frosst Canada and Co, Kirkland, Quebec, Canada, H9H 3L1.

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http://dx.doi.org/10.1208/pt060236DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2750539PMC
October 2005

Combining restricted access material (RAM) and turbulent flow for the rapid on-line extraction of the cyclooxygenase-2 inhibitor rofecoxib in plasma samples.

J Chromatogr A 2005 Aug;1082(2):150-7

Pharmaceutical Research and Development, Merck Frosst Center for Therapeutic Research, 16711 Trans-Canada Highway, Kirkland, Quebec, Canada.

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http://dx.doi.org/10.1016/j.chroma.2005.05.081DOI Listing
August 2005

Rapid quantitative analysis of magnesium stearate in tablets using laser-induced breakdown spectroscopy.

J Pharm Pharm Sci 2005 Aug 5;8(2):272-88. Epub 2005 Aug 5.

National Research Council Canada, Industrial Materials Institute, Boucherville, Québec, Canada.

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August 2005

Stir bar sorptive extraction based on restricted access material for the direct extraction of caffeine and metabolites in biological fluids.

J Chromatogr A 2005 May;1075(1-2):43-9

Department of Pharmaceutical Research and Development, Merck Frosst Canada & Co, 16711 TransCanada Highway, Kirkland, Que., Canada H9H 3L1

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http://dx.doi.org/10.1016/j.chroma.2005.03.119DOI Listing
May 2005

A method for the direct analysis of drug compounds in plasma using a single restricted access material (RAM) column.

J Pharm Biomed Anal 2004 Nov;36(3):457-64

Pharmaceutical Research and Development, Merck Frosst Center for Therapeutic Research, 16711 Trans-Canada Hwy., Kirkland, Que., Canada H9H 3L1.

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http://dx.doi.org/10.1016/j.jpba.2004.07.029DOI Listing
November 2004

Rapid analysis of liquid formulations containing sodium chloride using laser-induced breakdown spectroscopy.

J Pharm Biomed Anal 2004 Oct;36(2):277-84

National Research Council Canada, Industrial Materials Institute, 75 de Mortagne Blvd., Boucherville, Que., Canada J4B 6Y4.

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http://dx.doi.org/10.1016/j.jpba.2004.06.004DOI Listing
October 2004

Inhibition of cyclooxygenase-2 by rofecoxib attenuates the growth and metastatic potential of colorectal carcinoma in mice.

Cancer Res 2003 Feb;63(3):586-92

Section of Gastroenterology, Boston University School of Medicine and Boston Medical Center, Boston, Massachusetts 02118, USA.

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http://cancerres.aacrjournals.org/content/63/3/586.full.pdf
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February 2003

A SPME-GC procedure for monitoring peppermint flavor in tablets.

J Pharm Biomed Anal 2003 Jan;30(5):1469-77

Merck Frosst Canada and Co., 16711 Trans Canada Hwy, Quebec, Kirkland, Canada.

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http://dx.doi.org/10.1016/s0731-7085(02)00484-3DOI Listing
January 2003

No effect of cyclooxygenase inhibition on plaque size in atherosclerosis-prone mice.

Scand Cardiovasc J 2002 Dec;36(6):362-7

Department of Cardiology, Institute of Experimental Clinical Research, Aarhus University Hospital (Skejby), DK-8200 Aarhus N, Denmark.

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http://dx.doi.org/10.1080/140174302762659094DOI Listing
December 2002

Interaction of methylparaben preservative with selected sugars and sugar alcohols.

J Pharm Sci 2002 Jul;91(7):1715-23

Analytical Sciences, Amgen Inc., One Amgen Center Drive, Thousand Oaks, California 91320, USA.

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http://dx.doi.org/10.1002/jps.10167DOI Listing
July 2002