Publications Authored by Elizabeth Folkerd

Menstrual cycle associated changes in hormone-related gene expression in oestrogen receptor positive breast cancer.

NPJ Breast Cancer 2019 15;5:42. Epub 2019 Nov 15.

1The Ralph Lauren Centre for Breast Cancer Research, Royal Marsden Hospital, Fulham Road, London, UK.

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http://dx.doi.org/10.1038/s41523-019-0138-2	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6858333	PMC

November 2019

Circulating Growth and Sex Hormone Levels and Breast Tissue Composition in Young Nulliparous Women.

Authors:

Rachel Denholm Bianca L De Stavola John H Hipwell Simon J Doran Jeff M P Holly Elizabeth Folkerd Mitch Dowsett Martin O Leach David J Hawkes Isabel Dos-Santos-Silva

Cancer Epidemiol Biomarkers Prev 2018 12 18;27(12):1500-1508. Epub 2018 Sep 18.

Department of Non-Communicable Disease Epidemiology, London School of Hygiene & Tropical Medicine, London, United Kingdom.

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http://dx.doi.org/10.1158/1055-9965.EPI-18-0036	DOI Listing

December 2018

Abiraterone shows alternate activity in models of endocrine resistant and sensitive disease.

Authors:

Nikiana Simigdala Sunil Pancholi Ricardo Ribas Elizabeth Folkerd Gianmaria Liccardi Joanna Nikitorowicz-Buniak Stephen R Johnston Mitch Dowsett Lesley-Ann Martin

Br J Cancer 2018 08 11;119(3):313-322. Epub 2018 Jul 11.

The Breast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research, London, SW7 3RP, UK.

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http://dx.doi.org/10.1038/s41416-018-0158-y	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6068155	PMC

August 2018

Molecular changes in premenopausal oestrogen receptor-positive primary breast cancer in Vietnamese women after oophorectomy.

Authors:

Ben P Haynes Ophira Ginsburg Qiong Gao Elizabeth Folkerd Maria Afentakis Le Hong Quang Pham Thi Han Pham Hong Khoa Nguyen Van Dinh Ta Van To Mark Clemons Ian E Smith Mitch Dowsett

NPJ Breast Cancer 2017 27;3:47. Epub 2017 Nov 27.

The Ralph Lauren Centre for Breast Cancer Research, Royal Marsden Hospital, Fulham Road, London, UK.

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http://dx.doi.org/10.1038/s41523-017-0049-z	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5703856	PMC

November 2017

Palbociclib Combined with Fulvestrant in Premenopausal Women with Advanced Breast Cancer and Prior Progression on Endocrine Therapy: PALOMA-3 Results.

Authors:

Sibylle Loibl Nicholas C Turner Jungsil Ro Massimo Cristofanilli Hiroji Iwata Seock-Ah Im Norikazu Masuda Sherene Loi Fabrice André Nadia Harbeck Sunil Verma Elizabeth Folkerd Kathy Puyana Theall Justin Hoffman Ke Zhang Cynthia Huang Bartlett Mitchell Dowsett

Oncologist 2017 09 26;22(9):1028-1038. Epub 2017 Jun 26.

Royal Marsden Hospital and Institute of Cancer Research, London, UK.

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http://dx.doi.org/10.1634/theoncologist.2017-0072	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5599195	PMC

September 2017

Cholesterol biosynthesis pathway as a novel mechanism of resistance to estrogen deprivation in estrogen receptor-positive breast cancer.

Authors:

Nikiana Simigdala Qiong Gao Sunil Pancholi Hanne Roberg-Larsen Marketa Zvelebil Ricardo Ribas Elizabeth Folkerd Andrew Thompson Amandeep Bhamra Mitch Dowsett Lesley-Ann Martin

Breast Cancer Res 2016 06 1;18(1):58. Epub 2016 Jun 1.

The Breast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research, London, SW3 6JB, UK.

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http://dx.doi.org/10.1186/s13058-016-0713-5	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4888666	PMC

June 2016

CYP19A1 fine-mapping and Mendelian randomization: estradiol is causal for endometrial cancer.

Authors:

Deborah J Thompson Tracy A O'Mara Dylan M Glubb Jodie N Painter Timothy Cheng Elizabeth Folkerd Deborah Doody Joe Dennis Penelope M Webb Maggie Gorman Lynn Martin Shirley Hodgson Kyriaki Michailidou Jonathan P Tyrer Mel J Maranian Per Hall Kamila Czene Hatef Darabi Jingmei Li Peter A Fasching Alexander Hein Matthias W Beckmann Arif B Ekici Thilo Dörk Peter Hillemanns Matthias Dürst Ingo Runnebaum Hui Zhao Jeroen Depreeuw Stefanie Schrauwen Frederic Amant Ellen L Goode Brooke L Fridley Sean C Dowdy Stacey J Winham Helga B Salvesen Jone Trovik Tormund S Njolstad Henrica M J Werner Katie Ashton Tony Proietto Geoffrey Otton Luis Carvajal-Carmona Emma Tham Tao Liu Miriam Mints Rodney J Scott Mark McEvoy John Attia Elizabeth G Holliday Grant W Montgomery Nicholas G Martin Dale R Nyholt Anjali K Henders John L Hopper Nadia Traficante Matthias Ruebner Anthony J Swerdlow Barbara Burwinkel Hermann Brenner Alfons Meindl Hiltrud Brauch Annika Lindblom Diether Lambrechts Jenny Chang-Claude Fergus J Couch Graham G Giles Vessela N Kristensen Angela Cox Manjeet K Bolla Qin Wang Stig E Bojesen Mitul Shah Robert Luben Kay-Tee Khaw Paul D P Pharoah Alison M Dunning Ian Tomlinson Mitch Dowsett Douglas F Easton Amanda B Spurdle

Endocr Relat Cancer 2016 Feb 16;23(2):77-91. Epub 2015 Nov 16.

Department of Public Health and Primary CareCentre for Cancer Genetic Epidemiology, University of Cambridge, Strangeways Research Laboratory, Worts Causeway, Cambridge, Cambridge CB1 8RN, UKDepartment of Genetics and Computational BiologyQIMR Berghofer Medical Research Institute, Brisbane, Queensland, 4006, AustraliaWellcome Trust Centre for Human GeneticsUniversity of Oxford, Oxford OX3 7BN, UKAcademic Department of BiochemistryRoyal Marsden Hospital, London SW3 6JJ, UKDepartment of Clinical GeneticsSt George's Hospital Medical School, London SW17 0RE, UKDepartment of OncologyCentre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge CB1 8RN, UKDepartment of Medical Epidemiology and BiostatisticsKarolinska Institutet, Stockholm SE-171 77, SwedenDepartment of MedicineDivision of Hematology/Oncology, David Geffen School of Medicine, University of California at Los Angeles, Los Angeles, California 90095, USADepartment of Gynecology and ObstetricsUniversity Hospital Erlangen, Friedrich-Alexander-University Erlangen-Nuremberg, Erlangen 91054, GermanyInstitute of Human GeneticsUniversity Hospital Erlangen, Friedrich-Alexander-University Erlangen-Nuremberg, Erlangen 91054, GermanyGynaecology Research UnitHannover Medical School, Hannover 30625, GermanyClinics of Gynaecology and ObstetricsHannover Medical School, Hannover 30625, GermanyDepartment of GynaecologyJena University Hospital - Friedrich Schiller University, Jena 07743, GermanyVesalius Research CenterLeuven 3000, BelgiumLaboratory for Translational GeneticsDepartment of Oncology, University Hospitals Leuven, Leuven 3000, BelgiumDepartment of Obstetrics and GynecologyDivision of Gynecologic Oncology, University Hospitals, KU Leuven - University of Leuven, Leuven 3000, BelgiumDepartment of Health Sciences ResearchMayo Clinic, Rochester, Minnesota 55905, USADepartment of BiostatisticsUniversity of Kansas Medical Center, Kansas City, Kansas 66160, USADepartment of Obstetrics and GynecologyDivision of G

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http://dx.doi.org/10.1530/ERC-15-0386	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4697192	PMC

February 2016

Reduced progesterone levels explain the reduced risk of breast cancer in obese premenopausal women: a new hypothesis.

Authors:

Mitch Dowsett Elizabeth Folkerd

Breast Cancer Res Treat 2015 Jan 21;149(1):1-4. Epub 2014 Nov 21.

Academic Department of Biochemistry, Royal Marsden Hospital NHS Foundation Trust, Fulham Road, London, SW3 6JJ, UK.

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http://link.springer.com/content/pdf/10.1007%2Fs10549-014-32	Web Search
http://link.springer.com/10.1007/s10549-014-3211-4	Publisher Site
http://dx.doi.org/10.1007/s10549-014-3211-4	DOI Listing

January 2015

Reproducibility of estradiol and testosterone levels in postmenopausal women over 5 years: results from the breakthrough generations study.

Authors:

Michael E Jones Minouk J Schoemaker Megan Rae Elizabeth J Folkerd Mitch Dowsett Alan Ashworth Anthony J Swerdlow

Am J Epidemiol 2014 May 30;179(9):1128-33. Epub 2014 Mar 30.

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https://academic.oup.com/aje/article-lookup/doi/10.1093/aje/	Publisher Site
http://dx.doi.org/10.1093/aje/kwu027	DOI Listing

May 2014

Interpreting plasma estrogen levels in breast cancer: caution needed.

Authors:

Elizabeth J Folkerd Per E Lønning Mitch Dowsett

J Clin Oncol 2014 May 14;32(14):1396-400. Epub 2014 Apr 14.

The Institute of Cancer Research; Royal Marsden Hospital NHS Foundation Trust, London, United Kingdom.

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http://jco.ascopubs.org/content/early/2014/04/09/JCO.2013.53	Web Search
http://jco.ascopubs.org/cgi/doi/10.1200/JCO.2013.53.9411	Publisher Site
http://dx.doi.org/10.1200/JCO.2013.53.9411	DOI Listing

May 2014

Genetic variation at CYP3A is associated with age at menarche and breast cancer risk: a case-control study.

Authors:

Nichola Johnson Frank Dudbridge Nick Orr Lorna Gibson Michael E Jones Minouk J Schoemaker Elizabeth J Folkerd Ben P Haynes John L Hopper Melissa C Southey Gillian S Dite Carmel Apicella Marjanka K Schmidt Annegien Broeks Laura J Van't Veer Femke Atsma Kenneth Muir Artitaya Lophatananon Peter A Fasching Matthias W Beckmann Arif B Ekici Stefan P Renner Elinor Sawyer Ian Tomlinson Michael Kerin Nicola Miller Barbara Burwinkel Frederik Marme Andreas Schneeweiss Christof Sohn Pascal Guénel Therese Truong Emilie Cordina Florence Menegaux Stig E Bojesen Børge G Nordestgaard Henrik Flyger Roger Milne M Pilar Zamora Jose Ignacio Arias Perez Javier Benitez Leslie Bernstein Hoda Anton-Culver Argyrios Ziogas Christina Clarke Dur Hermann Brenner Heiko Müller Volker Arndt Aida Karina Dieffenbach Alfons Meindl Joerg Heil Claus R Bartram Rita K Schmutzler Hiltrud Brauch Christina Justenhoven Yon-Dschun Ko Heli Nevanlinna Taru A Muranen Kristiina Aittomäki Carl Blomqvist Keitaro Matsuo Thilo Dörk Natalia V Bogdanova Natalia N Antonenkova Annika Lindblom Arto Mannermaa Vesa Kataja Veli-Matti Kosma Jaana M Hartikainen Georgia Chenevix-Trench Jonathan Beesley Anna H Wu David Van den Berg Chiu-Chen Tseng Diether Lambrechts Dominiek Smeets Patrick Neven Hans Wildiers Jenny Chang-Claude Anja Rudolph Stefan Nickels Dieter Flesch-Janys Paolo Radice Paolo Peterlongo Bernardo Bonanni Valeria Pensotti Fergus J Couch Janet E Olson Xianshu Wang Zachary Fredericksen Vernon S Pankratz Graham G Giles Gianluca Severi Laura Baglietto Chris Haiman Jacques Simard Mark S Goldberg France Labrèche Martine Dumont Penny Soucy Soo Teo Cheng Har Yip Sze Yee Phuah Belinda K Cornes Vessela N Kristensen Grethe Grenaker Alnæs Anne-Lise Børresen-Dale Wei Zheng Robert Winqvist Katri Pylkäs Arja Jukkola-Vuorinen Mervi Grip Irene L Andrulis Julia A Knight Gord Glendon Anna Marie Mulligan Peter Devillee Jonine Figueroa Stephen J Chanock Jolanta Lissowska Mark E Sherman Per Hall Nils Schoof Maartje Hooning Antoinette Hollestelle Rogier A Oldenburg Madeleine Tilanus-Linthorst Jianjun Liu Angie Cox Ian W Brock Malcolm W R Reed Simon S Cross William Blot Lisa B Signorello Paul D P Pharoah Alison M Dunning Mitul Shah Daehee Kang Dong-Young Noh Sue K Park Ji-Yeob Choi Mikael Hartman Hui Miao Wei Yen Lim Anthony Tang Ute Hamann Asta Försti Thomas Rüdiger Hans Ulrich Ulmer Anna Jakubowska Jan Lubinski Katarzyna Jaworska-Bieniek Katarzyna Durda Suleeporn Sangrajrang Valerie Gaborieau Paul Brennan James McKay Susan Slager Amanda E Toland Celine Vachon Drakoulis Yannoukakos Chen-Yang Shen Jyh-Cherng Yu Chiun-Sheng Huang Ming-Feng Hou Anna González-Neira Daniel C Tessier Daniel Vincent Francois Bacot Craig Luccarini Joe Dennis Kyriaki Michailidou Manjeet K Bolla Jean Wang Douglas F Easton Montserrat García-Closas Mitch Dowsett Alan Ashworth Anthony J Swerdlow Julian Peto Isabel dos Santos Silva Olivia Fletcher

Breast Cancer Res 2014 May 26;16(3):R51. Epub 2014 May 26.

Breakthrough Breast Cancer Research Centre, The Institute of Cancer Research, 237 Fulham Road, London, SW3 6JB, UK.

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http://dx.doi.org/10.1186/bcr3662	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4522594	PMC

May 2014

Fulvestrant plus anastrozole or placebo versus exemestane alone after progression on non-steroidal aromatase inhibitors in postmenopausal patients with hormone-receptor-positive locally advanced or metastatic breast cancer (SoFEA): a composite, multicentre, phase 3 randomised trial.

Lancet Oncol 2013 Sep 29;14(10):989-98. Epub 2013 Jul 29.

Royal Marsden NHS Foundation Trust, London, UK.

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http://www.thelancet.com/pdfs/journals/lanonc/PIIS1470204513	Web Search
http://linkinghub.elsevier.com/retrieve/pii/S147020451370322	Publisher Site
http://dx.doi.org/10.1016/S1470-2045(13)70322-X	DOI Listing

September 2013

Sex hormones and breast cancer risk and prognosis.

Authors:

Elizabeth Folkerd Mitch Dowsett

Breast 2013 Aug;22 Suppl 2:S38-43

The Academic Department of Biochemistry, The Royal Marsden NHS Foundation Trust, Wallace Wing, Fulham Road, London SW3 6JJ, UK. Electronic address:

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http://dx.doi.org/10.1016/j.breast.2013.07.007	DOI Listing

August 2013

Changes in estradiol and testosterone levels in postmenopausal women after changes in body mass index.

Authors:

Michael E Jones Minouk Schoemaker Megan Rae Elizabeth J Folkerd Mitch Dowsett Alan Ashworth Anthony J Swerdlow

J Clin Endocrinol Metab 2013 Jul 10;98(7):2967-74. Epub 2013 May 10.

Division of Genetics and Epidemiology, The Institute of Cancer Research, University of London, Sutton SM2 5NG and London SW3 6JB, United Kingdom.

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http://dx.doi.org/10.1210/jc.2013-1588	DOI Listing

July 2013

A dual-center randomized controlled double blind trial assessing the effect of acupuncture in reducing musculoskeletal symptoms in breast cancer patients taking aromatase inhibitors.

Authors:

Ting Bao Ling Cai Jon T Giles Jeff Gould Karineh Tarpinian Kelly Betts Michelle Medeiros Stacie Jeter Nancy Tait Saranya Chumsri Deborah K Armstrong Ming Tan Elizabeth Folkerd Mitch Dowsett Harvinder Singh Kate Tkaczuk Vered Stearns

Breast Cancer Res Treat 2013 Feb 8;138(1):167-74. Epub 2013 Feb 8.

University of Maryland Greenebaum Cancer Center, Baltimore, MD 20201, USA.

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http://dx.doi.org/10.1007/s10549-013-2427-z	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3594526	PMC

February 2013

Reply to S. Pauwels et al.

Authors:

Elizabeth J Folkerd J Michael Dixon Roger P A' Hern Mitch Dowsett

J Clin Oncol 2013 Feb;31(4):509-10

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http://ascopubs.org/doi/10.1200/JCO.2012.47.0609	Publisher Site
http://dx.doi.org/10.1200/JCO.2012.47.0609	DOI Listing

February 2013

The heritability of mammographic breast density and circulating sex-hormone levels: two independent breast cancer risk factors.

Authors:

Jajini S Varghese Paula L Smith Elizabeth Folkerd Judith Brown Jean Leyland Tina Audley Ruth M L Warren Mitchell Dowsett Douglas F Easton Deborah J Thompson

Cancer Epidemiol Biomarkers Prev 2012 Dec 16;21(12):2167-75. Epub 2012 Oct 16.

Department of Public Heath and Primary Care, Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge, UK.

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http://cebp.aacrjournals.org/cgi/doi/10.1158/1055-9965.EPI-1	Publisher Site
http://dx.doi.org/10.1158/1055-9965.EPI-12-0789	DOI Listing

December 2012

Genome-wide association study of circulating estradiol, testosterone, and sex hormone-binding globulin in postmenopausal women.

Authors:

Jennifer Prescott Deborah J Thompson Peter Kraft Stephen J Chanock Tina Audley Judith Brown Jean Leyland Elizabeth Folkerd Deborah Doody Susan E Hankinson David J Hunter Kevin B Jacobs Mitch Dowsett David G Cox Douglas F Easton Immaculata De Vivo

PLoS One 2012 4;7(6):e37815. Epub 2012 Jun 4.

Channing Laboratory, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0037815	PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3366971	PMC

October 2012

Suppression of plasma estrogen levels by letrozole and anastrozole is related to body mass index in patients with breast cancer.

Authors:

Elizabeth J Folkerd J Michael Dixon Lorna Renshaw Roger P A'Hern Mitch Dowsett

J Clin Oncol 2012 Aug 16;30(24):2977-80. Epub 2012 Jul 16.

Royal Marsden Hospital, London, United Kingdom.

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http://dx.doi.org/10.1200/JCO.2012.42.0273	DOI Listing

August 2012

CYP3A variation, premenopausal estrone levels, and breast cancer risk.

J Natl Cancer Inst 2012 May 3;104(9):657-69. Epub 2012 Apr 3.

The Breakthrough Breast Cancer Research Centre, Division of Breast Cancer Research, Institute of Cancer Research, London, UK.

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http://dx.doi.org/10.1093/jnci/djs156	DOI Listing

May 2012

Effects of vaginal estrogens on serum estradiol levels in postmenopausal breast cancer survivors and women at risk of breast cancer taking an aromatase inhibitor or a selective estrogen receptor modulator.

Authors:

Shannon Wills Anita Ravipati Padmaja Venuturumilli Cynthia Kresge Elizabeth Folkerd Mitch Dowsett Daniel F Hayes David A Decker

J Oncol Pract 2012 May 7;8(3):144-8. Epub 2012 Feb 7.

William Beaumont Hospital, Royal Oak; University of Michigan Comprehensive Cancer Center, Ann Arbor, MI; and The Royal Marsden Hospital and Institute of Cancer Research, London, United Kingdom.

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http://dx.doi.org/10.1200/JOP.2011.000352	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3396801	PMC

May 2012

Testosterone, SHBG and differential white blood cell count in middle-aged and older men.

Authors:

Judith S Brand Yvonne T van der Schouw Mitch Dowsett Elizabeth Folkerd Robert N Luben Nicholas J Wareham Kay-Tee Khaw

Maturitas 2012 Mar 4;71(3):274-8. Epub 2012 Jan 4.

Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, 3508 GA Utrecht, The Netherlands.

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http://dx.doi.org/10.1016/j.maturitas.2011.12.007	DOI Listing

March 2012

A short-term biomarker modulation study of simvastatin in women at increased risk of a new breast cancer.

Breast Cancer Res Treat 2012 Feb 11;131(3):915-24. Epub 2011 Nov 11.

The Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, 1650 Orleans Street, CRBI, Room 144, Baltimore, MD 21231, USA.

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http://link.springer.com/10.1007/s10549-011-1858-7	Publisher Site
http://dx.doi.org/10.1007/s10549-011-1858-7	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3536477	PMC

February 2012

Clinical and biochemical consequences of CYP17A1 inhibition with abiraterone given with and without exogenous glucocorticoids in castrate men with advanced prostate cancer.

Authors:

Gerhardt Attard Alison H M Reid Richard J Auchus Beverly A Hughes Amy Mulick Cassidy Emilda Thompson Nikhil Babu Oommen Elizabeth Folkerd Mitch Dowsett Wiebke Arlt Johann S de Bono

J Clin Endocrinol Metab 2012 Feb 14;97(2):507-16. Epub 2011 Dec 14.

The Institute of Cancer Research, Sutton, Surrey SM2 5PT, UK.

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http://dx.doi.org/10.1210/jc.2011-2189	DOI Listing

February 2012

Changes in breast density and circulating estrogens in postmenopausal women receiving adjuvant anastrozole.

Authors:

Tatiana M Prowell Amanda L Blackford Celia Byrne Nagi F Khouri Mitchell Dowsett Elizabeth Folkerd Karineh S Tarpinian Pendleton P Powers Laurie A Wright Michele G Donehower Stacie C Jeter Deborah K Armstrong Leisha A Emens John H Fetting Antonio C Wolff Elizabeth Garrett-Mayer Todd C Skaar Nancy E Davidson Vered Stearns

Cancer Prev Res (Phila) 2011 Dec 1;4(12):1993-2001. Epub 2011 Sep 1.

Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.

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http://dx.doi.org/10.1158/1940-6207.CAPR-11-0154	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3700336	PMC

December 2011

Cigarette smoking and endogenous sex hormones in postmenopausal women.

Authors:

Judith S Brand Mei-Fen Chan Mitch Dowsett Elizabeth Folkerd Nicholas J Wareham Robert N Luben Yvonne T van der Schouw Kay-Tee Khaw

J Clin Endocrinol Metab 2011 Oct 10;96(10):3184-92. Epub 2011 Aug 10.

Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, 3508 CA Utrecht, The Netherlands.

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http://dx.doi.org/10.1210/jc.2011-1165	DOI Listing

October 2011

Associations of endogenous testosterone and SHBG with glycated haemoglobin in middle-aged and older men.

Authors:

Judith S Brand Nicholas J Wareham Mitch Dowsett Elizabeth Folkerd Yvonne T van der Schouw Robert N Luben Kay-Tee Khaw

Clin Endocrinol (Oxf) 2011 May;74(5):572-8

Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands.

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http://dx.doi.org/10.1111/j.1365-2265.2010.03951.x	DOI Listing

May 2011

Influence of sex hormones on cancer progression.

Authors:

Elizabeth J Folkerd Mitch Dowsett

J Clin Oncol 2010 Sep 19;28(26):4038-44. Epub 2010 Jul 19.

The Academic Department of Biochemistry, the Royal Marsden NHS Foundation Trust, Fulham Rd, London, SW3 6JJ, United Kingdom.

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http://dx.doi.org/10.1200/JCO.2009.27.4290	DOI Listing

September 2010

Relationship between plasma estradiol levels and estrogen-responsive gene expression in estrogen receptor-positive breast cancer in postmenopausal women.

Authors:

Anita K Dunbier Helen Anderson Zara Ghazoui Elizabeth J Folkerd Roger A'hern Robert J Crowder Jeremy Hoog Ian E Smith Peter Osin Ashutosh Nerurkar Joel S Parker Charles M Perou Matthew J Ellis Mitch Dowsett

J Clin Oncol 2010 Mar 1;28(7):1161-7. Epub 2010 Feb 1.

Academic Department of Biochemistry, Royal Marsden Hospital, Fulham Rd, London, SW3 6JJ, United Kingdom.

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http://dx.doi.org/10.1200/JCO.2009.23.9616	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2834467	PMC

March 2010

Sex steroids, growth factors and mammographic density: a cross-sectional study of UK postmenopausal Caucasian and Afro-Caribbean women.

Authors:

Valerie A McCormack Mitch Dowsett Elizabeth Folkerd Nichola Johnson Claire Palles Ben Coupland Jeff M Holly Sarah J Vinnicombe Nicholas M Perry Isabel dos Santos Silva

Breast Cancer Res 2009 22;11(3):R38. Epub 2009 Jun 22.

Cancer Research UK Epidemiology and Genetics Group, Department of Epidemiology and Population Health, London School of Hygiene & Tropical Medicine, London, UK.

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http://dx.doi.org/10.1186/bcr2325	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2716507	PMC

January 2010

Familial correlations in postmenopausal serum concentrations of sex steroid hormones and other mitogens: a twins and sisters study.

Authors:

Jennifer Stone Elizabeth Folkerd Deborah Doody Chris Schroen Susan A Treloar Graham G Giles Malcolm C Pike Dallas R English Melissa C Southey John L Hopper Mitch Dowsett

J Clin Endocrinol Metab 2009 Dec 22;94(12):4793-800. Epub 2009 Oct 22.

Centre for Molecular, Environmental, Genetic, and Analytic Epidemiology, University of Melbourne, Level 1, 723 Swanston Street, Carlton, Victoria 3053 Australia.

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http://dx.doi.org/10.1210/jc.2009-0713	DOI Listing

December 2009

Association between endogenous plasma hormone concentrations and fracture risk in men and women: the EPIC-Oxford prospective cohort study.

Authors:

Andrew W Roddam Paul Appleby Rachel Neale Mitch Dowsett Elizabeth Folkerd Sarah Tipper Naomi E Allen Timothy J Key

J Bone Miner Metab 2009 31;27(4):485-93. Epub 2009 Mar 31.

Cancer Epidemiology Unit, University of Oxford, Richard Doll Building, Roosevelt Drive, Oxford, OX3 7LF, UK.

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http://dx.doi.org/10.1007/s00774-009-0060-z	DOI Listing

September 2009

Selective inhibition of CYP17 with abiraterone acetate is highly active in the treatment of castration-resistant prostate cancer.

Authors:

Gerhardt Attard Alison H M Reid Roger A'Hern Christopher Parker Nikhil Babu Oommen Elizabeth Folkerd Christina Messiou L Rhoda Molife Gal Maier Emilda Thompson David Olmos Rajesh Sinha Gloria Lee Mitch Dowsett Stan B Kaye David Dearnaley Thian Kheoh Arturo Molina Johann S de Bono

J Clin Oncol 2009 Aug 26;27(23):3742-8. Epub 2009 May 26.

Royal Marsden National Health Service Foundation Trust, Sutton, Surrey, United Kingdom.

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http://dx.doi.org/10.1200/JCO.2008.20.0642	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3535569	PMC

August 2009

Premenopausal mammographic density in relation to cyclic variations in endogenous sex hormone levels, prolactin, and insulin-like growth factors.

Authors:

Kate Walker Olivia Fletcher Nichola Johnson Ben Coupland Valerie A McCormack Elizabeth Folkerd Lorna Gibson Stephen G Hillier Jeff M Holly Sue Moss Mitchell Dowsett Julian Peto Isabel dos Santos Silva

Cancer Res 2009 Aug;69(16):6490-9

Department of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, and The Academic Department of Biochemistry, The Royal Marsden Hospital, London, UK.

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http://dx.doi.org/10.1158/0008-5472.CAN-09-0280	DOI Listing

August 2009

Identification of common variants in the SHBG gene affecting sex hormone-binding globulin levels and breast cancer risk in postmenopausal women.

Authors:

Deborah J Thompson Catherine S Healey Caroline Baynes Bolot Kalmyrzaev Shahana Ahmed Mitch Dowsett Elizabeth Folkerd Robert N Luben David Cox Dennis Ballinger Paul D P Pharoah Bruce A J Ponder Alison M Dunning Douglas F Easton

Cancer Epidemiol Biomarkers Prev 2008 Dec;17(12):3490-8

Cambridge University, Strangeways Research Laboratories, Worts Causeway, Cambridge CB1 8RN, United Kingdom.

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http://cebp.aacrjournals.org/cgi/doi/10.1158/1055-9965.EPI-0	Publisher Site
http://dx.doi.org/10.1158/1055-9965.EPI-08-0734	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2660245	PMC

December 2008

Phase I clinical trial of a selective inhibitor of CYP17, abiraterone acetate, confirms that castration-resistant prostate cancer commonly remains hormone driven.

Authors:

Gerhardt Attard Alison H M Reid Timothy A Yap Florence Raynaud Mitch Dowsett Sarah Settatree Mary Barrett Christopher Parker Vanessa Martins Elizabeth Folkerd Jeremy Clark Colin S Cooper Stan B Kaye David Dearnaley Gloria Lee Johann S de Bono

J Clin Oncol 2008 Oct 21;26(28):4563-71. Epub 2008 Jul 21.

Royal Marsden NHS Foundation Trust, Sutton, Surrey, United Kingdom.

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http://dx.doi.org/10.1200/JCO.2007.15.9749	DOI Listing

October 2008

Past oral contraceptive and hormone therapy use and endogenous hormone concentrations in postmenopausal women.

Authors:

Mei-Fen Chan Mitch Dowsett Elizabeth Folkerd Nicholas Wareham Robert Luben Ailsa Welch Sheila Bingham Kay-Tee Khaw

Menopause 2008 Mar-Apr;15(2):332-9

Department of Public Health and Primary Care, University of Cambridge School of Clinical Medicine, Cambridge, United Kingdom.

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https://insights.ovid.com/crossref?an=00042192-900000000-997	Publisher Site
http://dx.doi.org/10.1097/gme.0b013e31806458d9	DOI Listing

July 2008

Letrozole suppresses plasma estradiol and estrone sulphate more completely than anastrozole in postmenopausal women with breast cancer.

Authors:

J Michael Dixon Lorna Renshaw Oliver Young Juliette Murray E Jane Macaskill Mary McHugh Elizabeth Folkerd David A Cameron Roger P A'Hern Mitch Dowsett

J Clin Oncol 2008 Apr;26(10):1671-6

Edinburgh Breast Unit, Western General Hospital, Edinburgh EH4 2XU, United Kingdom.

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http://dx.doi.org/10.1200/JCO.2007.13.9279	DOI Listing

April 2008

Endogenous testosterone and mortality due to all causes, cardiovascular disease, and cancer in men: European prospective investigation into cancer in Norfolk (EPIC-Norfolk) Prospective Population Study.

Authors:

Kay-Tee Khaw Mitch Dowsett Elizabeth Folkerd Sheila Bingham Nicholas Wareham Robert Luben Ailsa Welch Nicholas Day

Circulation 2007 Dec 26;116(23):2694-701. Epub 2007 Nov 26.

Clinical Gerontology Unit Box 251, Addenbrooke's Hospital, Cambridge CB2 2QQ, UK. cam.ac.uk

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https://www.ahajournals.org/doi/10.1161/CIRCULATIONAHA.107.7	Publisher Site
http://dx.doi.org/10.1161/CIRCULATIONAHA.107.719005	DOI Listing

December 2007

Effect of delays in processing blood samples on measured endogenous plasma sex hormone levels in women.

Authors:

Michael E Jones Elizabeth J Folkerd Deborah A Doody Jhangir Iqbal Mitch Dowsett Alan Ashworth Anthony J Swerdlow

Cancer Epidemiol Biomarkers Prev 2007 Jun;16(6):1136-9

Section of Epidemiology, The Institute of Cancer Research, Sir Richard Doll Building, Sutton, Surrey SM2 5NG, United Kingdom.

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http://dx.doi.org/10.1158/1055-9965.EPI-07-0028	DOI Listing

June 2007

Usual physical activity and endogenous sex hormones in postmenopausal women: the European prospective investigation into cancer-norfolk population study.

Authors:

Mei-Fen Chan Mitch Dowsett Elizabeth Folkerd Sheila Bingham Nicholas Wareham Robert Luben Ailsa Welch Kay-Tee Khaw

Cancer Epidemiol Biomarkers Prev 2007 May;16(5):900-5

Department of Public Health and Primary Care, Institute of Public Health, University of Cambridge School of Clinical Medicine, Cambridge, United Kingdom.

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http://dx.doi.org/10.1158/1055-9965.EPI-06-0745	DOI Listing

May 2007

Phytoestrogen exposure is associated with circulating sex hormone levels in postmenopausal women and interact with ESR1 and NR1I2 gene variants.

Authors:

Yen-Ling Low Alison M Dunning Mitch Dowsett Elizabeth Folkerd Deborah Doody James Taylor Amit Bhaniani Robert Luben Kay-Tee Khaw Nick J Wareham Sheila A Bingham

Cancer Epidemiol Biomarkers Prev 2007 May;16(5):1009-16

Medical Research Council Dunn Human Nutrition Unit, Wellcome Trust/Medical Research Council Dunn Human Nutrition Unit Building, Hills Road, Cambridge CB2 2XY, United Kingdom.

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