Publications by authors named "Elizabeth E Gardiner"

100Publications

Phosphoproteomic Analysis of Platelets in Severe Obesity Uncovers Platelet Reactivity and Signaling Pathways Alterations.

Arterioscler Thromb Vasc Biol 2020 Nov 5:ATVBAHA120314485. Epub 2020 Nov 5.

Platelet Proteomics Group, Center for Research in Molecular Medicine and Chronic Diseases (CIMUS), Universidade Santiago de Compostela (M.N.B., L.H.-N., L.A.M., Á.G.).

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http://dx.doi.org/10.1161/ATVBAHA.120.314485DOI Listing
November 2020

The molecular basis of immune-based platelet disorders.

Clin Sci (Lond) 2020 Nov;134(21):2807-2822

ACRF Department of Cancer Biology and Therapeutics, The John Curtin School of Medical Research, The Australian National University, Canberra, Australia.

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http://dx.doi.org/10.1042/CS20191101DOI Listing
November 2020

Differential Role of Glycoprotein VI in Mouse and Human Thrombus Progression and Stability.

Thromb Haemost 2020 Oct 29. Epub 2020 Oct 29.

Université de Strasbourg, INSERM, EFS Grand-Est, BPPS UMR-S1255, FMTS, F-67065 Strasbourg, France.

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http://dx.doi.org/10.1055/s-0040-1718737DOI Listing
October 2020

Targeting shear gradient activated von Willebrand factor by the novel single-chain antibody A1 reduces occlusive thrombus formation in vitro.

Haematologica 2020 Sep 21;Online ahead of print. Epub 2020 Sep 21.

Baker Heart and Diabetes Institute, Melbourne; Australian Centre for Blood Diseases, Monash University, Melbourne; CEH and EW contributed equally to this work.

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http://dx.doi.org/10.3324/haematol.2020.250761DOI Listing
September 2020

Free Reelin' Along the Platelet Surface.

Arterioscler Thromb Vasc Biol 2020 10 23;40(10):2341-2343. Epub 2020 Sep 23.

ACRF Department of Cancer Biology and Therapeutics, The John Curtin School of Medical Research, The Australian National University, Canberra (S.M.H., E.E.G.).

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http://dx.doi.org/10.1161/ATVBAHA.120.314980DOI Listing
October 2020

Modified inverted selective plane illumination microscopy for sub-micrometer imaging resolution in polydimethylsiloxane soft lithography devices.

Lab Chip 2020 10;20(21):3960-3969

Research School of Electrical, Energy and Materials Engineering, College of Engineering and Computer Science, The Australian National University, Canberra, ACT 2601, Australia. and ACRF Department of Cancer Biology and Therapeutics, The John Curtin School of Medical Research, The Australian National University, Canberra, ACT 2601, Australia and ARC Centre of Excellence in Advanced Molecular Imaging, The Australian National University, Canberra, ACT 2601, Australia.

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http://dx.doi.org/10.1039/d0lc00598cDOI Listing
October 2020

Soluble glycoprotein VI is a predictor of major bleeding in patients with suspected heparin-induced thrombocytopenia.

Blood Adv 2020 Sep;4(18):4327-4332

Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA.

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http://dx.doi.org/10.1182/bloodadvances.2020002861DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7509866PMC
September 2020

Pharmacological Blockade of Glycoprotein VI Promotes Thrombus Disaggregation in the Absence of Thrombin.

Arterioscler Thromb Vasc Biol 2020 09 23;40(9):2127-2142. Epub 2020 Jul 23.

From the Université de Strasbourg, INSERM, EFS Grand-Est, BPPS UMR-S1255, FMTS, F-67065 Strasbourg, France (M.U.A., N.R., M.L.B., E.J.-B., F.L., C.G., P.H.M.).

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http://dx.doi.org/10.1161/ATVBAHA.120.314301DOI Listing
September 2020

Analysis of the (PAR4) Single Nucleotide Polymorphism () in an Indigenous Australian Population.

Front Genet 2020 30;11:432. Epub 2020 Apr 30.

Department of Immunology and Infectious Disease, The John Curtin School of Medical Research, The Australian National University, Canberra, ACT, Australia.

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http://dx.doi.org/10.3389/fgene.2020.00432DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7204273PMC
April 2020

Raster adaptive optics for video rate aberration correction and large FOV multiphoton imaging.

Biomed Opt Express 2020 Feb 23;11(2):1032-1042. Epub 2020 Jan 23.

Research School of Electrical, Energy and Materials Engineering, College of Engineering and Computer Science, The Australian National University, 31 North Road, Canberra, ACT, 2601, Australia.

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http://dx.doi.org/10.1364/BOE.377044DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7041464PMC
February 2020

Fibrin exposure triggers αIIbβ3-independent platelet aggregate formation, ADAM10 activity and glycoprotein VI shedding in a charge-dependent manner.

J Thromb Haemost 2020 06 16;18(6):1447-1458. Epub 2020 Apr 16.

ACRF Department of Cancer Biology and Therapeutics, The John Curtin School of Medical Research, The Australian National University, Canberra, ACT, Australia.

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http://dx.doi.org/10.1111/jth.14797DOI Listing
June 2020

Imaging Platelet Processes and Function-Current and Emerging Approaches for Imaging and .

Front Immunol 2020 31;11:78. Epub 2020 Jan 31.

ACRF Department of Cancer Biology and Therapeutics, The John Curtin School of Medical Research, The Australian National University, Canberra, ACT, Australia.

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http://dx.doi.org/10.3389/fimmu.2020.00078DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7005007PMC
January 2020

Novel scientific approaches and future research directions in understanding ITP.

Platelets 2020 13;31(3):315-321. Epub 2020 Feb 13.

ACRF Department of Cancer Biology and Therapeutics, The John Curtin School of Medical Research, The Australian National University, Canberra, Australia.

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http://dx.doi.org/10.1080/09537104.2020.1727871DOI Listing
September 2020

Plasma levels of the soluble form of the FcγRIIa receptor vary with receptor polymorphisms and are elevated in rheumatoid arthritis.

Platelets 2020 4;31(3):392-398. Epub 2019 Aug 4.

ACRF Department of Cancer Biology and Therapeutics, John Curtin School of Medical Research, The Australian National University, Canberra, Australia.

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http://dx.doi.org/10.1080/09537104.2019.1647527DOI Listing
September 2020

All-Trans Retinoic Acid Impairs Platelet Function and Thrombus Formation and Inhibits Protein Kinase CßI/δ Phosphorylation.

Thromb Haemost 2019 10 1;119(10):1655-1664. Epub 2019 Aug 1.

Blood Diseases Institute, Xuzhou Medical University, Xuzhou, China.

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http://dx.doi.org/10.1055/s-0039-1693737DOI Listing
October 2019

Parkin the bus to manage stress.

EMBO Mol Med 2019 08 17;11(8):e10968. Epub 2019 Jul 17.

ACRF Department of Cancer Biology and Therapeutics, John Curtin School of Medical Research, Australian National University, Canberra, ACT, Australia.

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http://dx.doi.org/10.15252/emmm.201910968DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6685080PMC
August 2019

Adenosine and Forskolin Inhibit Platelet Aggregation by Collagen but not the Proximal Signalling Events.

Thromb Haemost 2019 Jul 26;119(7):1124-1137. Epub 2019 May 26.

Institute of Cardiovascular Sciences, Level 1 IBR, College of Medical and Dental Sciences, University of Birmingham, Edgbaston, Birmingham, United Kingdom.

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http://www.thieme-connect.de/DOI/DOI?10.1055/s-0039-1688788
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http://dx.doi.org/10.1055/s-0039-1688788DOI Listing
July 2019

Autologous platelet-rich plasma for healing chronic venous leg ulcers: Clinical efficacy and potential mechanisms.

Int Wound J 2019 Jun 12;16(3):788-792. Epub 2019 Mar 12.

Australian Centre for Blood Diseases, Monash University, Melbourne, Victoria, Australia.

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http://dx.doi.org/10.1111/iwj.13098DOI Listing
June 2019

Platelet Ubiquitylation-It's Everywhere.

Thromb Haemost 2019 01 31;119(1):6-8. Epub 2018 Dec 31.

Australian Centre for Blood Diseases, Monash University, Melbourne, Australia.

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http://dx.doi.org/10.1055/s-0038-1676650DOI Listing
January 2019

SerpinB2 deficiency in mice reduces bleeding times via dysregulated platelet activation.

Platelets 2019 2;30(5):658-663. Epub 2018 Nov 2.

a QIMR Berghofer Medical Research Institute , Brisbane , Australia.

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http://dx.doi.org/10.1080/09537104.2018.1535702DOI Listing
November 2019

Mechanisms of receptor shedding in platelets.

Blood 2018 12 22;132(24):2535-2545. Epub 2018 Oct 22.

Australian Cancer Research Foundation (ACRF) Department of Cancer Biology and Therapeutics, The John Curtin School of Medical Research, The Australian National University, Canberra, ACT, Australia; and.

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http://www.bloodjournal.org/lookup/doi/10.1182/blood-2018-03
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http://dx.doi.org/10.1182/blood-2018-03-742668DOI Listing
December 2018

Monitoring the pulse of thrombus formation: Comment on "Modeling thrombosis in silico: Frontiers, challenges, unresolved problems and milestones" by A.V. Belyaev et al.

Phys Life Rev 2018 11 24;26-27:113-115. Epub 2018 Jul 24.

ACRF Department of Cancer Biology and Therapeutics, The John Curtin School of Medical Research, The Australian National University, Canberra, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.plrev.2018.07.001DOI Listing
November 2018

Matrix metalloproteinase-13 unlucky for the forming thrombus.

Res Pract Thromb Haemost 2018 Jul 1;2(3):525-528. Epub 2018 May 1.

ACRF Department of Cancer Biology and Therapeutics John Curtin School of Medical Research The Australian National University Canberra ACT Australia.

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http://dx.doi.org/10.1002/rth2.12105DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6046591PMC
July 2018

Proteolytic processing of platelet receptors.

Res Pract Thromb Haemost 2018 Apr 10;2(2):240-250. Epub 2018 Apr 10.

ACRF Department of Cancer Biology and Therapeutics John Curtin School of Medical Research The Australian National University Canberra ACT Australia.

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http://dx.doi.org/10.1002/rth2.12096DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6055504PMC
April 2018

Anti-glycoprotein VI mediated immune thrombocytopenia: An under-recognized and significant entity?

Res Pract Thromb Haemost 2017 Oct 24;1(2):291-295. Epub 2017 Aug 24.

Department of Haematology and Transfusion Medicine Royal North Shore Hospital Sydney NSW Australia.

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http://doi.wiley.com/10.1002/rth2.12033
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http://dx.doi.org/10.1002/rth2.12033DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6058269PMC
October 2017

Bone Marrow Defects and Platelet Function: A Focus on MDS and CLL.

Cancers (Basel) 2018 May 18;10(5). Epub 2018 May 18.

Australian Centre for Blood Diseases, Monash University, Melbourne, VIC 3004, Australia.

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http://www.mdpi.com/2072-6694/10/5/147
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http://dx.doi.org/10.3390/cancers10050147DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5977120PMC
May 2018

High contrast imaging and flexible photomanipulation for quantitative in vivo multiphoton imaging with polygon scanning microscope.

J Biophotonics 2018 07 10;11(7):e201700341. Epub 2018 Apr 10.

Research School of Engineering, College of Engineering and Computer Science, The Australian National University, Canberra, ACT, Australia.

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http://dx.doi.org/10.1002/jbio.201700341DOI Listing
July 2018

Mechanisms of Platelet Dysfunction in Patients with Implantable Devices.

Semin Thromb Hemost 2018 Feb 12;44(1):12-19. Epub 2017 Sep 12.

Hematology Unit, Alfred Hospital, Melbourne, Australia.

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http://dx.doi.org/10.1055/s-0037-1605572DOI Listing
February 2018

Regulation of platelet activation and thrombus formation by reactive oxygen species.

Redox Biol 2018 04 8;14:126-130. Epub 2017 Sep 8.

Blood Diseases Institute, Xuzhou Medical University, Xuzhou, China; Department of Hematology, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, China; Key Laboratory of Bone Marrow Stem Cell, Xuzhou, Jiangsu Province, China. Electronic address:

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http://dx.doi.org/10.1016/j.redox.2017.08.021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5596263PMC
April 2018

The cutting edge of platelets.

Platelets 2017 06;28(4):317-318

b ACRF Department of Cancer Biology and Therapeutics , John Curtin School of Medical Research, Australian National University , Canberra , Australia .

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http://dx.doi.org/10.1080/09537104.2017.1338397DOI Listing
June 2017

Basic mechanisms of platelet receptor shedding.

Platelets 2017 Jun 25;28(4):319-324. Epub 2016 Oct 25.

a Australian Centre for Blood Diseases , Monash University , Melbourne , Australia 3004.

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http://dx.doi.org/10.1080/09537104.2016.1235690DOI Listing
June 2017

Metalloproteolytic receptor shedding…platelets "acting their age".

Platelets 2016 Sep 26;27(6):512-8. Epub 2016 Jul 26.

b Department of Cancer Biology and Therapeutics, John Curtin School of Medical Research , Australian National University , Canberra , Australia.

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http://dx.doi.org/10.1080/09537104.2016.1212001DOI Listing
September 2016

Colocalization of neutrophils, extracellular DNA and coagulation factors during NETosis: Development and utility of an immunofluorescence-based microscopy platform.

J Immunol Methods 2016 08 7;435:77-84. Epub 2016 Jun 7.

Department of Cell, Developmental & Cancer Biology, Oregon Health & Science University, Portland, OR, USA; Department of Biomedical Engineering, Oregon Health & Science University, Portland, OR, USA.

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http://dx.doi.org/10.1016/j.jim.2016.06.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4935600PMC
August 2016

Longitudinal changes in hemostatic parameters and reduced pulsatility contribute to non-surgical bleeding in patients with centrifugal continuous-flow left ventricular assist devices.

J Heart Lung Transplant 2016 06 7;35(6):743-51. Epub 2016 Jan 7.

Heart Failure and Transplant Unit, St. Vincent's Hospital, Sydney, New South Wales, Australia;; Faculty of Medicine, University of New South Wales, Sydney, New South Wales, Australia; Victor Chang Cardiac Research Institute, Sydney, New South Wales, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.healun.2015.12.024DOI Listing
June 2016

A-Disintegrin-And-Metalloproteinase (ADAM) 10 Activity on Resting and Activated Platelets.

Biochemistry 2016 Mar 16;55(8):1187-94. Epub 2016 Feb 16.

Australian Centre for Blood Diseases, Monash University , Melbourne, Victoria, Australia 3004.

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http://pubs.acs.org/doi/10.1021/acs.biochem.5b01102
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http://dx.doi.org/10.1021/acs.biochem.5b01102DOI Listing
March 2016

Methods to Determine the Lagrangian Shear Experienced by Platelets during Thrombus Growth.

PLoS One 2015 14;10(12):e0144860. Epub 2015 Dec 14.

Department of Mechanical and Aerospace Engineering, Monash University, Melbourne, Victoria, Australia.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0144860PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4682839PMC
June 2016

Thrombin-induced reactive oxygen species generation in platelets: A novel role for protease-activated receptor 4 and GPIbα.

Redox Biol 2015 Dec 28;6:640-647. Epub 2015 Oct 28.

Department of Experimental Medicine, Royal College of Surgeons in Ireland, Dublin, Ireland; Faculty of Health Sciences, Curtin University, Perth, Australia; Curtin Health Innovation Research Institute, Curtin University, Perth, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.redox.2015.10.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4656914PMC
December 2015

Effects of abacavir administration on structural and functional markers of platelet activation.

AIDS 2015 Nov;29(17):2309-13

aDepartment of Infectious Diseases, Alfred Hospital bDepartment of Infectious Diseases, Faculty of Medicine, Nursing and Health Sciences, cAustralian Centre for Bloods Diseases, Monash University, Melbourne, Australia.

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http://dx.doi.org/10.1097/QAD.0000000000000848DOI Listing
November 2015

The platelet Fc receptor, FcγRIIa.

Immunol Rev 2015 Nov;268(1):241-52

The Australian Centre for Blood Diseases, Monash University, Melbourne, VIC, Australia.

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http://dx.doi.org/10.1111/imr.12370DOI Listing
November 2015

Low levels of CD9 coincidental with a novel nonsense mutation in glycoprotein Ibβ in a patient with Bernard-Soulier syndrome.

Ann Hematol 2015 Dec 16;94(12):2069-71. Epub 2015 Aug 16.

Australian Centre for Blood Diseases, Monash University, Melbourne, Australia.

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http://dx.doi.org/10.1007/s00277-015-2473-1DOI Listing
December 2015

Editorial: ADAMs control inflammation from afar.

J Leukoc Biol 2015 Mar;97(3):437-8

Australian Centre for Blood Diseases, Monash University, Melbourne, Victoria, Australia

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http://dx.doi.org/10.1189/jlb.3CE1114-528RDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5477894PMC
March 2015

Phosphorothioate backbone modifications of nucleotide-based drugs are potent platelet activators.

J Exp Med 2015 Feb 2;212(2):129-37. Epub 2015 Feb 2.

Baker IDI Heart and Diabetes Institute, St. Vincent's Institute of Medical Research, and Bio21 Institute, University of Melbourne, Melbourne, Victoria 3010, Australia

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http://dx.doi.org/10.1084/jem.20140391DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4322051PMC
February 2015

Extracorporeal membrane oxygenation-hemostatic complications.

Transfus Med Rev 2015 Apr 18;29(2):90-101. Epub 2014 Dec 18.

Department of Haematology, Alfred Hospital Melbourne, Australia.

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http://dx.doi.org/10.1016/j.tmrv.2014.12.001DOI Listing
April 2015

Structure and function of platelet receptors initiating blood clotting.

Adv Exp Med Biol 2014 ;844:263-75

Australian Centre for Blood Diseases, Monash University, Melbourne, VIC, Australia.

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http://dx.doi.org/10.1007/978-1-4939-2095-2_13DOI Listing
April 2015

Neutrophil extracellular traps (NETs) and the role of platelets in infection.

Thromb Haemost 2014 Oct 21;112(4):659-65. Epub 2014 Aug 21.

Dr. Elizabeth E. Gardiner, Australian Centre for Blood Diseases, Monash University, Level 6, 89 Commercial Road,, Melbourne, Victoria, 3004, Australia, Tel.: +613 9903 0756, E-mail:

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http://www.actabp.pl/pdf/3_2013/277.pdf
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http://www.schattauer.de/index.php?id=1214&doi=10.1160/T
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http://dx.doi.org/10.1160/TH14-05-0455DOI Listing
October 2014

CLEC-2 expression is maintained on activated platelets and on platelet microparticles.

Blood 2014 Oct 22;124(14):2262-70. Epub 2014 Aug 22.

Centre for Cardiovascular Sciences, College of Medical and Dental Sciences, National Institute for Health Research Surgical Reconstruction and Microbiology Research Centre, and.

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http://dx.doi.org/10.1182/blood-2014-05-572818DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4183985PMC
October 2014

Targeting GPVI as a novel antithrombotic strategy.

J Blood Med 2014 21;5:59-68. Epub 2014 May 21.

Australian Centre for Blood Diseases, Monash University, Melbourne, VIC, Australia.

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http://dx.doi.org/10.2147/JBM.S39220DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4039396PMC
June 2014

Lymphomania.

Blood 2014 May;123(20):3057-8

MONASH UNIVERSITY.

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http://dx.doi.org/10.1182/blood-2014-02-557371DOI Listing
May 2014

DiagnoSTic assays for heparin-induced thrombocytopenia.

Br J Haematol 2014 Sep 14;166(5):631-3. Epub 2014 May 14.

Australian Centre for Blood Diseases, Monash University, Melbourne, Vic., Australia.

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http://dx.doi.org/10.1111/bjh.12940DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4134688PMC
September 2014

Platelet receptor expression and shedding: glycoprotein Ib-IX-V and glycoprotein VI.

Transfus Med Rev 2014 Apr 12;28(2):56-60. Epub 2014 Mar 12.

Australian Centre for Blood Diseases, Monash University, Melbourne, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.tmrv.2014.03.001DOI Listing
April 2014

Plasma sGPVI: Changing levels in human disease.

Thromb Res 2014 Mar 22;133(3):306-7. Epub 2013 Dec 22.

Australian Centre for Blood Diseases, Monash University, Alfred Medical Research & Education Precinct (AMREP), 89 Commercial Road, Melbourne, Victoria, 3004. Electronic address:

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http://dx.doi.org/10.1016/j.thromres.2013.12.028DOI Listing
March 2014

Platelets: envoys at the infection frontline.

J Infect Dis 2013 Sep 11;208(6):871-3. Epub 2013 Jul 11.

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https://academic.oup.com/jid/article-lookup/doi/10.1093/infd
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http://dx.doi.org/10.1093/infdis/jit305DOI Listing
September 2013

Histone deacetylase inhibitors reduce glycoprotein VI expression and platelet responses to collagen related peptide.

Thromb Res 2013 Jun 2;131(6):514-20. Epub 2013 May 2.

Cancer Research Division, The Peter MacCallum Cancer Centre, St. Andrew's Place, East Melbourne 3002, Victoria, Australia.

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http://dx.doi.org/10.1016/j.thromres.2013.02.013DOI Listing
June 2013

Mice lacking the ITIM-containing receptor G6b-B exhibit macrothrombocytopenia and aberrant platelet function.

Sci Signal 2012 Oct 30;5(248):ra78. Epub 2012 Oct 30.

Centre of Cardiovascular Sciences, Institute of Biomedical Research, School of Clinical and Experimental Medicine, College of Medical and Dental Sciences, University of Birmingham, Birmingham B15 2TT, UK.

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http://dx.doi.org/10.1126/scisignal.2002936DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4973664PMC
October 2012

Neutrophil extracellular traps (NETs) and infection-related vascular dysfunction.

Blood Rev 2012 Nov 26;26(6):255-9. Epub 2012 Sep 26.

Australian Centre for Blood Diseases, Monash University, Melbourne, Australia.

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http://dx.doi.org/10.1016/j.blre.2012.09.001DOI Listing
November 2012

An acquired defect associated with abnormal signaling of the platelet collagen receptor glycoprotein VI.

Acta Haematol 2012 24;128(4):233-41. Epub 2012 Aug 24.

Australian Centre for Blood Diseases, Monash University, Melbourne, Vic., Australia.

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http://dx.doi.org/10.1159/000340048DOI Listing
January 2013

Diesel exhaust particles impair platelet response to collagen and are associated with GPIbα shedding.

Toxicol In Vitro 2012 Sep 20;26(6):930-8. Epub 2012 Apr 20.

Department of Internal Medicine, Laboratory for Thrombosis Research, Cantonal Hospital Baden, Switzerland.

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http://linkinghub.elsevier.com/retrieve/pii/S088723331200098
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http://dx.doi.org/10.1016/j.tiv.2012.04.009DOI Listing
September 2012

Inside platelets...

Blood 2012 Jan;119(4):907-9

Monash University.

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http://www.bloodjournal.org/cgi/doi/10.1182/blood-2011-11-39
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http://dx.doi.org/10.1182/blood-2011-11-391292DOI Listing
January 2012

Platelet receptor shedding.

Methods Mol Biol 2012 ;788:321-39

Australian Centre for Blood Diseases, Monash University, Melbourne, VIC, Australia.

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http://dx.doi.org/10.1007/978-1-61779-307-3_22DOI Listing
April 2012

Coagulation-induced shedding of platelet glycoprotein VI mediated by factor Xa.

Blood 2011 Apr 20;117(14):3912-20. Epub 2011 Jan 20.

Australian Centre for Blood Diseases, Monash University, Alfred Medical Research and Education Precinct, Commercial Road, Melbourne, Australia.

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http://www.bloodjournal.org/content/117/14/3912.full.pdf
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http://www.bloodjournal.org/content/early/2011/01/20/blood-2
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http://www.bloodjournal.org/cgi/doi/10.1182/blood-2010-08-30
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http://dx.doi.org/10.1182/blood-2010-08-301523DOI Listing
April 2011

Arterial thrombosis: going, gone!

Blood 2010 Sep;116(13):2201-2

Monash University and Dublin City University.

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http://dx.doi.org/10.1182/blood-2010-06-291492DOI Listing
September 2010

Proteolysis of platelet receptors in humans and other species.

Biol Chem 2010 Aug;391(8):893-900

Australian Centre for Blood Diseases, Monash University, Melbourne, Victoria, Australia.

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http://dx.doi.org/10.1515/BC.2010.081DOI Listing
August 2010

Nerve growth factor inhibits metalloproteinase-disintegrins and blocks ectodomain shedding of platelet glycoprotein VI.

J Biol Chem 2010 Apr 17;285(16):11793-9. Epub 2010 Feb 17.

Department of Biochemistry and Molecular Biology, Monash University, Melbourne, Victoria 3004, Australia.

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http://dx.doi.org/10.1074/jbc.M110.100479DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2852915PMC
April 2010

Measuring soluble platelet glycoprotein VI in human plasma by ELISA.

Platelets 2009 May;20(3):143-9

Department of Immunology, Monash University, Alfred Medical Research & Education Precinct, Melbourne, Australia.

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http://dx.doi.org/10.1080/09537100802710286DOI Listing
May 2009

Anti-glycoprotein VI monoclonal antibodies directly aggregate platelets independently of FcgammaRIIa and induce GPVI ectodomain shedding.

Platelets 2009 Mar;20(2):75-82

Department of Immunology, Australian Centre for Blood Diseases, Monash University, Melbourne, Australia.

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http://dx.doi.org/10.1080/09537100802645029DOI Listing
March 2009

Antihemostatic activity of human granzyme B mediated by cleavage of von Willebrand factor.

J Biol Chem 2008 Aug 24;283(33):22498-504. Epub 2008 Jun 24.

Department of Biochemistry and Molecular Biology, Monash University, Clayton 3800, Victoria, Australia.

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http://dx.doi.org/10.1074/jbc.M709080200DOI Listing
August 2008

Platelet receptor redox regulation.

Platelets 2008 Feb;19(1):1-8

Department of Immunology, Monash University, Alfred Medical Research & Education Precinct, Melbourne 3004, Victoria, Australia.

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http://dx.doi.org/10.1080/09537100701817224DOI Listing
February 2008

Snake venom metalloproteinases, crotarhagin and alborhagin, induce ectodomain shedding of the platelet collagen receptor, glycoprotein VI.

Thromb Haemost 2007 Dec;98(6):1285-90

Department of Biochemistry and Molecular Biology, Monash University, Alfred Medical Research & Education Precinct, Melbourne, Victoria, Australia.

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December 2007

Fractionation of snake venom metalloproteinases by metal ion affinity: a purified cobra metalloproteinase, Nk, from Naja kaouthia binds Ni2+-agarose.

Toxicon 2007 Dec 28;50(8):1064-72. Epub 2007 Jul 28.

Department of Biochemistry and Molecular Biology, Monash University, Clayton, 3008 Victoria, Australia.

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http://dx.doi.org/10.1016/j.toxicon.2007.07.006DOI Listing
December 2007

Ligand binding rapidly induces disulfide-dependent dimerization of glycoprotein VI on the platelet plasma membrane.

J Biol Chem 2007 Oct 9;282(42):30434-41. Epub 2007 Aug 9.

Department of Immunology, Monash University, Melbourne 3004, Australia.

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http://dx.doi.org/10.1074/jbc.M701330200DOI Listing
October 2007

A familial platelet function disorder associated with abnormal signalling through the glycoprotein VI pathway.

Br J Haematol 2007 Jun;137(6):569-77

Institute of Haematology, Royal Prince Alfred Hospital, Camperdown, NSW, Australia.

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http://dx.doi.org/10.1111/j.1365-2141.2007.06603.xDOI Listing
June 2007

Platelet receptor proteolysis: a mechanism for downregulating platelet reactivity.

Arterioscler Thromb Vasc Biol 2007 Jul 26;27(7):1511-20. Epub 2007 Apr 26.

Department of Immunology, Monash University, Alfred Medical Research & Education Precinct, Melbourne 3004, Australia.

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http://dx.doi.org/10.1161/ATVBAHA.107.141390DOI Listing
July 2007

Role of calmodulin in platelet receptor function.

Curr Med Chem Cardiovasc Hematol Agents 2005 Oct;3(4):283-7

Department of Biochemistry and Molecular Biology, Monash University, Clayton, VIC 3168, Australia.

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http://dx.doi.org/10.2174/156801605774322283DOI Listing
October 2005

Glycoprotein VI is associated with GPIb-IX-V on the membrane of resting and activated platelets.

Thromb Haemost 2005 Apr;93(4):716-23

Department of Biochemistry and Molecular Biology, Monash University, Clayton, Victoria 3168, Australia.

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http://www.thieme-connect.de/DOI/DOI?10.1160/TH04-09-0584
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April 2005

Structure-activity relationships of snake toxins targeting platelet receptors, glycoprotein Ib-IX-V and glycoprotein VI.

Curr Med Chem Cardiovasc Hematol Agents 2003 Jun;1(2):143-9

Vascular Biology Laboratory, Department of Biochemistry and Molecular Biology, Monash University, Clayton 3168, Australia.

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http://dx.doi.org/10.2174/1568016033477559DOI Listing
June 2003