Publications by authors named "Elizabeth Culp"

8Publications

GPAHex-A synthetic biology platform for Type IV-V glycopeptide antibiotic production and discovery.

Nat Commun 2020 10 16;11(1):5232. Epub 2020 Oct 16.

David Braley Center for Antibiotic Discovery, M.G. DeGroote Institute for Infectious Disease Research, Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, ON, Canada.

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October 2020

Genome editing in the nematode using the CRISPR/Cas9 system.

Biol Methods Protoc 2020 10;5(1):bpaa003. Epub 2020 Feb 10.

Department of Biology, McMaster University, 1280 Main Street West, Hamilton, ON L8S-4K1, Canada.

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February 2020

Evolution-guided discovery of antibiotics that inhibit peptidoglycan remodelling.

Nature 2020 02 12;578(7796):582-587. Epub 2020 Feb 12.

M. G. DeGroote Institute for Infectious Disease Research, David Braley Centre for Antibiotic Discovery, Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, Ontario, Canada.

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February 2020

Hidden antibiotics in actinomycetes can be identified by inactivation of gene clusters for common antibiotics.

Nat Biotechnol 2019 10 9;37(10):1149-1154. Epub 2019 Sep 9.

David Braley Center for Antibiotic Discovery, M.G. DeGroote Institute for Infectious Disease Research, Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, Ontario, Canada.

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October 2019

The ADEP Biosynthetic Gene Cluster in Streptomyces hawaiiensis NRRL 15010 Reveals an Accessory Gene as a Novel Antibiotic Resistance Factor.

Appl Environ Microbiol 2019 10 1;85(20). Epub 2019 Oct 1.

Department of Microbial Bioactive Compounds, Interfaculty Institute of Microbiology and Infection Medicine, University of Tuebingen, Tuebingen, Germany

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October 2019

Transformation of the Anticancer Drug Doxorubicin in the Human Gut Microbiome.

ACS Infect Dis 2018 01 30;4(1):68-76. Epub 2017 Nov 30.

M. G. DeGroote Institute for Infectious Disease Research, McMaster University , 1280 Main Street West, Hamilton, Ontario L8S 4K1, Canada.

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January 2018

Bacterial proteases, untapped antimicrobial drug targets.

J Antibiot (Tokyo) 2017 Apr 30;70(4):366-377. Epub 2016 Nov 30.

Michael G. DeGroote Institute for Infectious Disease Research and the Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, Ontario, Canada.

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April 2017