Elizabeth B Klerman

Elizabeth B Klerman

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Elizabeth B Klerman

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Circadian Neurobiology and the Physiologic Regulation of Sleep and Wakefulness.

Neurol Clin 2019 Aug 7;37(3):475-486. Epub 2019 May 7.

Division of Sleep and Circadian Disorders, Department of Medicine, Brigham and Women's Hospital, 221 Longwood Avenue, Boston, MA 02115, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ncl.2019.03.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6604835PMC
August 2019

An Exploration of the Temporal Dynamics of Circadian Resetting Responses to Short- and Long-Duration Light Exposures: Cross-Species Consistencies and Differences.

J Biol Rhythms 2019 Aug 1:748730419862702. Epub 2019 Aug 1.

Division of Sleep Medicine, Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.1177/0748730419862702DOI Listing
August 2019

Why Should We Abolish Daylight Saving Time?

J Biol Rhythms 2019 Jun;34(3):227-230

Division of Sleep and Circadian Disorders, Brigham and Women's Hospital, Harvard University, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1177/0748730419854197DOI Listing
June 2019

Chronic sleep restriction greatly magnifies performance decrements immediately after awakening.

Sleep 2019 May;42(5)

Division of Sleep and Circadian Disorders, Departments of Medicine and Neurology, Brigham and Women's Hospital, Boston, MA.

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http://dx.doi.org/10.1093/sleep/zsz032DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6519907PMC
May 2019

Mathematical modeling of circadian rhythms.

Wiley Interdiscip Rev Syst Biol Med 2019 Mar 17;11(2):e1439. Epub 2018 Oct 17.

Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.

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http://doi.wiley.com/10.1002/wsbm.1439
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http://dx.doi.org/10.1002/wsbm.1439DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6375788PMC
March 2019

Diurnal variation of metabolites in three individual participants.

Chronobiol Int 2019 Mar 17;36(3):332-342. Epub 2018 Dec 17.

b Division of Cancer Epidemiology and Genetics , National Cancer Institute , Rockville , MD , USA.

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http://dx.doi.org/10.1080/07420528.2018.1541901DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6448392PMC
March 2019

Caloric and Macronutrient Intake Differ with Circadian Phase and between Lean and Overweight Young Adults.

Nutrients 2019 03 11;11(3). Epub 2019 Mar 11.

Division of Sleep and Circadian Disorders, Departments of Medicine and Neurology, Brigham and Women's Hospital, 221 Longwood Ave, Boston, MA 02115, USA.

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https://www.mdpi.com/2072-6643/11/3/587
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http://dx.doi.org/10.3390/nu11030587DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6471585PMC
March 2019

Dose-Dependent Associations Between Sleep Duration and Unsafe Behaviors Among US High School Students.

JAMA Pediatr 2018 Dec;172(12):1187-1189

Division of Sleep and Circadian Disorders, Brigham and Women's Hospital, Boston, Massachusetts.

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http://dx.doi.org/10.1001/jamapediatrics.2018.2777DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6366445PMC
December 2018

Longitude Position in a Time Zone and Cancer Risk-Response.

Cancer Epidemiol Biomarkers Prev 2018 09;27(9):1111-1112

Division of Cancer Epidemiology and Genetics, NCI, Bethesda, Maryland.

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http://dx.doi.org/10.1158/1055-9965.EPI-17-1199DOI Listing
September 2018

Functional decoupling of melatonin suppression and circadian phase resetting in humans.

J Physiol 2018 06 29;596(11):2147-2157. Epub 2018 Apr 29.

Division of Sleep and Circadian Disorders, Departments of Medicine and Neurology, Brigham & Women's Hospital, Boston, MA, USA.

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http://dx.doi.org/10.1113/JP275501DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5983136PMC
June 2018

Chronic sleep curtailment, even without extended (>16-h) wakefulness, degrades human vigilance performance.

Proc Natl Acad Sci U S A 2018 06 21;115(23):6070-6075. Epub 2018 May 21.

Division of Sleep and Circadian Disorders, Department of Medicine, Brigham and Women's Hospital, Boston, MA 02115;

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http://dx.doi.org/10.1073/pnas.1706694115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6003377PMC
June 2018

Chronic Insufficient Sleep Has a Limited Impact on Circadian Rhythmicity of Subjective Hunger and Awakening Fasted Metabolic Hormones.

Front Endocrinol (Lausanne) 2018 12;9:319. Epub 2018 Jun 12.

Division of Sleep and Circadian Disorders, Department of Medicine, Brigham and Women's Hospital, Boston, MA, United States.

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http://dx.doi.org/10.3389/fendo.2018.00319DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6005823PMC
June 2018

Human fatigue and the crash of the airship .

Polar Res 2016 29;35(1). Epub 2016 Jul 29.

Division of Sleep and Circadian Disorders, Brigham and Women's Hospital, 221 Longwood Avenue, Boston, MA 02115, USA.

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http://dx.doi.org/10.3402/polar.v35.27105DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5421565PMC
March 2018

Later circadian timing of food intake is associated with increased body fat.

Am J Clin Nutr 2017 Nov 6;106(5):1213-1219. Epub 2017 Sep 6.

Sleep Health Institute and Division of Sleep and Circadian Disorders, Departments of Medicine and Neurology, and.

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http://dx.doi.org/10.3945/ajcn.117.161588DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5657289PMC
November 2017

Light Therapy Promoting Dopamine Release by Stimulating Retina in Parkinson Disease-Reply.

JAMA Neurol 2017 10;74(10):1268-1269

Department of Neurology, Northwestern University, Chicago, Illinois.

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http://dx.doi.org/10.1001/jamaneurol.2017.1909DOI Listing
October 2017

Modeling the adenosine system as a modulator of cognitive performance and sleep patterns during sleep restriction and recovery.

PLoS Comput Biol 2017 Oct 26;13(10):e1005759. Epub 2017 Oct 26.

Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, and Department of Medicine, Harvard Medical School, Boston, MA, United States of America.

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http://dx.doi.org/10.1371/journal.pcbi.1005759DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5675465PMC
October 2017

Longitude Position in a Time Zone and Cancer Risk in the United States.

Cancer Epidemiol Biomarkers Prev 2017 08 27;26(8):1306-1311. Epub 2017 Apr 27.

Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland.

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http://dx.doi.org/10.1158/1055-9965.EPI-16-1029DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6436388PMC
August 2017

Irregular sleep/wake patterns are associated with poorer academic performance and delayed circadian and sleep/wake timing.

Sci Rep 2017 06 12;7(1):3216. Epub 2017 Jun 12.

Sleep Health Institute and Division of Sleep and Circadian Disorders, Departments of Medicine and Neurology, Brigham and Women's Hospital, Boston, MA, USA.

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http://dx.doi.org/10.1038/s41598-017-03171-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5468315PMC
June 2017

Are Individual Differences in Sleep and Circadian Timing Amplified by Use of Artificial Light Sources?

J Biol Rhythms 2017 04 2;32(2):165-176. Epub 2017 Apr 2.

Division of Sleep and Circadian Disorders, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1177/0748730417699310DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5593073PMC
April 2017

Circadian phase resetting by a single short-duration light exposure.

JCI Insight 2017 04 6;2(7):e89494. Epub 2017 Apr 6.

Division of Sleep and Circadian Disorders, Departments of Medicine and Neurology, Brigham and Women's Hospital, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1172/jci.insight.89494DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5374060PMC
April 2017

The Relationship Between Estrogen and the Decline in Delta Power During Adolescence.

Sleep 2017 03;40(3)

Reproductive Endocrine Unit, Department of Medicine, Massachusetts General Hospital, Boston, MA.

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http://dx.doi.org/10.1093/sleep/zsx008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5806564PMC
March 2017

Statistics for Sleep and Biological Rhythms Research.

J Biol Rhythms 2017 02 25;32(1):7-17. Epub 2016 Oct 25.

Division of Sleep Medicine, Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.1177/0748730416670050DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5501416PMC
February 2017

Statistics for Sleep and Biological Rhythms Research.

J Biol Rhythms 2017 02 25;32(1):18-25. Epub 2016 Oct 25.

Neurology Department, Massachusetts General Hospital, Boston, Massachusetts.

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http://dx.doi.org/10.1177/0748730416670051DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5483995PMC
February 2017

Multimodal Ambulatory Sleep Detection.

IEEE EMBS Int Conf Biomed Health Inform 2017 Feb 13;2017:465-468. Epub 2017 Apr 13.

Affective Computing Group, Media Lab, Massachusetts Institute of Technology.

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http://dx.doi.org/10.1109/BHI.2017.7897306DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6010306PMC
February 2017

Applying mathematical models to predict resident physician performance and alertness on traditional and novel work schedules.

BMC Med Educ 2016 Sep 13;16(1):239. Epub 2016 Sep 13.

Division of Sleep and Circadian Disorders, Departments of Neurology and Medicine, Brigham and Women's Hospital, Boston, MA, 02115, USA.

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http://dx.doi.org/10.1186/s12909-016-0751-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5022151PMC
September 2016

Prediction of Vigilant Attention and Cognitive Performance Using Self-Reported Alertness, Circadian Phase, Hours since Awakening, and Accumulated Sleep Loss.

PLoS One 2016 28;11(3):e0151770. Epub 2016 Mar 28.

Division of Sleep and Circadian Disorders, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0151770PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4809494PMC
August 2016

Effect of Slow Wave Sleep Disruption on Metabolic Parameters in Adolescents.

Sleep 2016 Aug 1;39(8):1591-9. Epub 2016 Aug 1.

Reproductive Endocrine Unit, Department of Medicine, Massachusetts General Hospital, Boston, MA.

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http://dx.doi.org/10.5665/sleep.6028DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4945319PMC
August 2016

Thalamic mechanisms underlying alpha-delta sleep with implications for fibromyalgia.

J Neurophysiol 2015 Sep 5;114(3):1923-30. Epub 2015 Aug 5.

Department of Mathematics and Statistics, Boston University, Boston, Massachusetts;

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http://dx.doi.org/10.1152/jn.00280.2015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4575971PMC
September 2015

Biological time series analysis using a context free language: applicability to pulsatile hormone data.

PLoS One 2014 3;9(9):e104087. Epub 2014 Sep 3.

Division of Sleep and Circadian Disorders, Brigham and Women's Hospital, Boston, Massachusetts, United States of America; Harvard Medical School, Boston, Massachusetts, United States of America; Division of Endocrinology, Diabetes and Hypertension, Brigham and Women's Hospital, Boston, Massachusetts, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0104087PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4153563PMC
May 2015

Deconvolution of serum cortisol levels by using compressed sensing.

PLoS One 2014 28;9(1):e85204. Epub 2014 Jan 28.

Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Boston, Massachusetts, United States of America ; Institute for Medical Engineering and Science, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America ; Harvard Medical School, Boston, Massachusetts, United States of America ; Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0085204PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3904842PMC
December 2014

Absence of central circadian pacemaker abnormalities in humans with loss of function mutation in prokineticin 2.

J Clin Endocrinol Metab 2014 Mar 1;99(3):E561-6. Epub 2014 Jan 1.

Harvard Reproductive Endocrine Sciences Center and the Reproductive Endocrine Unit of the Department of Medicine (R.B., J.E.H., A.A.D., N.P., W.F.C.), Massachusetts General Hospital, Boston, Massachusetts 02114; Division of Sleep Medicine (D.A.C., E.B.K., C.A.C.), Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts 02115; and Department of Endocrinology-Hospital São João (D.P.), Department of Experimental Biology-Faculty of Medicine (D.P.), and Institute of Molecular Pathology and Immunology at the University of Porto (IPATIMUP) (D.P.), 4200-319 Porto, Portugal.

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http://dx.doi.org/10.1210/jc.2013-2096DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3942237PMC
March 2014

A mathematical model of the circadian phase-shifting effects of exogenous melatonin.

J Biol Rhythms 2013 Feb;28(1):79-89

Division of Sleep Medicine, Brigham & Women's Hospital, Harvard Medical School, MA 02115, USA.

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http://dx.doi.org/10.1177/0748730412468081DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3733227PMC
February 2013

Survival analysis indicates that age-related decline in sleep continuity occurs exclusively during NREM sleep.

Neurobiol Aging 2013 Jan 23;34(1):309-18. Epub 2012 Jun 23.

Division of Sleep Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.

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http://dx.doi.org/10.1016/j.neurobiolaging.2012.05.018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3469724PMC
January 2013

Classifying performance impairment in response to sleep loss using pattern recognition algorithms on single session testing.

Accid Anal Prev 2013 Jan 5;50:992-1002. Epub 2012 Sep 5.

Analytic and Modeling Unit, Division of Sleep Medicine, Brigham and Women's Hospital, 221 Longwood Avenue, Boston, MA 02115, USA.

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http://dx.doi.org/10.1016/j.aap.2012.08.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3513628PMC
January 2013

Sleep misperception in healthy adults: implications for insomnia diagnosis.

J Clin Sleep Med 2012 Oct 15;8(5):547-54. Epub 2012 Oct 15.

Sleep Division, Neurology Department, Massachusetts General Hospital, Boston, MA 02114, USA.

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http://jcsm.aasm.org/ViewAbstract.aspx?pid=28675
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http://dx.doi.org/10.5664/jcsm.2154DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3459201PMC
October 2012

Instantaneous monitoring of sleep fragmentation by point process heart rate variability and respiratory dynamics.

Conf Proc IEEE Eng Med Biol Soc 2011 ;2011:7735-8

Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital - Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1109/IEMBS.2011.6091906DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3275421PMC
May 2012

Revisiting spontaneous internal desynchrony using a quantitative model of sleep physiology.

J Biol Rhythms 2011 Oct;26(5):441-53

Division of Sleep Medicine, Brigham & Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.

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http://dx.doi.org/10.1177/0748730411414163DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3557950PMC
October 2011

Absence of circadian rhythms of gonadotropin secretion in women.

J Clin Endocrinol Metab 2011 May 23;96(5):1456-61. Epub 2011 Feb 23.

Reproductive Endocrine Unit, Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02114, USA.

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http://dx.doi.org/10.1210/jc.2010-2739DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3085210PMC
May 2011

Ramelteon prior to a short evening nap impairs neurobehavioral performance for up to 12 hours after awakening.

J Clin Sleep Med 2010 Dec;6(6):565-71

Division of Sleep Medicine, Brigham and Women's Hospital, 221 Longwood Avenue, BL 438, Boston, MA 02115, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3014243PMC
December 2010

Abnormal sleep/wake dynamics in orexin knockout mice.

Sleep 2010 Mar;33(3):297-306

Department of Neurology, Beth Israel Deaconess Medical Center Boston, MA, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2831423PMC
http://dx.doi.org/10.1093/sleep/33.3.297DOI Listing
March 2010

Uncovering residual effects of chronic sleep loss on human performance.

Sci Transl Med 2010 Jan;2(14):14ra3

Division of Sleep Medicine, Brigham and Women's Hospital, Boston, MA 02115, USA.

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http://dx.doi.org/10.1126/scitranslmed.3000458DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2892834PMC
January 2010

Taking the lag out of jet lag through model-based schedule design.

PLoS Comput Biol 2009 Jun 19;5(6):e1000418. Epub 2009 Jun 19.

Division of Sleep Medicine, Brigham & Women's Hospital, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1371/journal.pcbi.1000418DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2691990PMC
June 2009

Age-related reduction in the maximal capacity for sleep--implications for insomnia.

Curr Biol 2008 Aug 24;18(15):1118-23. Epub 2008 Jul 24.

Division of Sleep Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S09609822080080
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http://dx.doi.org/10.1016/j.cub.2008.06.047DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2582347PMC
August 2008

Measuring melatonin in humans.

J Clin Sleep Med 2008 Feb;4(1):66-9

Department of Neurology, Northwestern University Medical School, Chicago, IL, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2276833PMC
February 2008

A physiologically based mathematical model of melatonin including ocular light suppression and interactions with the circadian pacemaker.

J Pineal Res 2007 Oct;43(3):294-304

Division of Sleep Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA.

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http://dx.doi.org/10.1111/j.1600-079X.2007.00477.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2714090PMC
October 2007

Addition of a non-photic component to a light-based mathematical model of the human circadian pacemaker.

J Theor Biol 2007 Aug 4;247(4):583-99. Epub 2007 Apr 4.

Analytic and Modeling Unit, Division of Sleep Medicine, Brigham and Women's Hospital/Harvard Medical School, Boston, MA 02115, USA.

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http://dx.doi.org/10.1016/j.jtbi.2007.04.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3123888PMC
August 2007

Uncovering physiologic mechanisms of circadian rhythms and sleep/wake regulation through mathematical modeling.

J Biol Rhythms 2007 Jun;22(3):233-45

Division of Sleep Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, Division of Applied Sciences, Harvard University, Cambridge, MA 02115, USA.

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http://journals.sagepub.com/doi/10.1177/0748730407301237
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http://dx.doi.org/10.1177/0748730407301237DOI Listing
June 2007

Developing mathematical models of neurobehavioral performance for the "real world".

J Biol Rhythms 2007 Jun;22(3):246-58

Division of Sleep Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA.

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http://dx.doi.org/10.1177/0748730407301376DOI Listing
June 2007

On mathematical modeling of circadian rhythms, performance, and alertness.

J Biol Rhythms 2007 Apr;22(2):91-102

Division of Sleep Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA.

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http://journals.sagepub.com/doi/10.1177/0748730407299200
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http://dx.doi.org/10.1177/0748730407299200DOI Listing
April 2007

Elevated body temperature during sleep in orexin knockout mice.

Am J Physiol Regul Integr Comp Physiol 2006 Sep;291(3):R533-40

Department of Neurology, Beth Israel Deaconess Medical Center, Boston, Massachusetts 02115, USA.

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http://www.physiology.org/doi/10.1152/ajpregu.00887.2005
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http://dx.doi.org/10.1152/ajpregu.00887.2005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2259440PMC
September 2006

Development of a two-dimension manifold to represent high dimension mathematical models of the intracellular Mammalian circadian clock.

J Biol Rhythms 2006 Jun;21(3):222-32

Biomathematical Modeling Unit, Division of Sleep Medicine, Brigham and Women's Hospital/Harvard Medical School, Boston, MA, USA.

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http://jbr.sagepub.com/content/21/3/222.full.pdf
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http://jbr.sagepub.com/cgi/doi/10.1177/0748730406287357
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http://dx.doi.org/10.1177/0748730406287357DOI Listing
June 2006

Comparison of amplitude recovery dynamics of two limit cycle oscillator models of the human circadian pacemaker.

Chronobiol Int 2005 ;22(4):613-29

Biomathematical Modeling Unit, Division of Sleep Medicine, Brigham and Women's Hospital/Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1080/07420520500180371DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3797655PMC
October 2005

Interindividual variation in sleep duration and its association with sleep debt in young adults.

Sleep 2005 Oct;28(10):1253-9

Division of Sleep Medicine, Brigham and Women's Hospital, Boston, MA 02115, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1351048PMC
http://dx.doi.org/10.1093/sleep/28.10.1253DOI Listing
October 2005

Clinical aspects of human circadian rhythms.

J Biol Rhythms 2005 Aug;20(4):375-86

Division of Sleep Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA.

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http://dx.doi.org/10.1177/0748730405278353DOI Listing
August 2005

Older people awaken more frequently but fall back asleep at the same rate as younger people.

Sleep 2004 Jun;27(4):793-8

Division of Sleep Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA.

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http://dx.doi.org/10.1093/sleep/27.4.793DOI Listing
June 2004

A statistical model of diurnal variation in human growth hormone.

Am J Physiol Endocrinol Metab 2003 Nov 29;285(5):E1118-26. Epub 2003 Jul 29.

Division of Sleep Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, 221 Longwood Ave., Boston, MA 02115, USA.

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http://dx.doi.org/10.1152/ajpendo.00562.2002DOI Listing
November 2003

Comparisons of the variability of three markers of the human circadian pacemaker.

J Biol Rhythms 2002 Apr;17(2):181-93

Division of Sleep Medicine, Brigham & Women's Hospital, Boston, MA 02115, USA.

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http://dx.doi.org/10.1177/074873002129002474DOI Listing
April 2002

Peak of circadian melatonin rhythm occurs later within the sleep of older subjects.

Am J Physiol Endocrinol Metab 2002 Feb;282(2):E297-303

Division of Sleep Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.

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http://dx.doi.org/10.1152/ajpendo.00268.2001DOI Listing
February 2002