Elissa K Deenick

Elissa K Deenick

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Elissa K Deenick

Elissa K Deenick

Publications by authors named "Elissa K Deenick"

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54Publications

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Activating mutations in PIK3CD disrupt the differentiation and function of human and murine CD4 T cells.

J Allergy Clin Immunol 2019 Jul 6;144(1):236-253. Epub 2019 Feb 6.

Immunology Division, Garvan Institute of Medical Research, Darlinghurst, Australia; St Vincent's Clinical School, University of New South Wales, Sydney, Australia; Clinical Immunogenomics Research Consortia Australia, Sydney, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2019.01.033DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6612302PMC
July 2019

B cell-intrinsic requirement for STK4 in humoral immunity in mice and human subjects.

J Allergy Clin Immunol 2019 Jun 20;143(6):2302-2305. Epub 2019 Feb 20.

Immunology Division, Garvan Institute of Medical Research, Sydney, Australia; St Vincent's Clinical School, Faculty of Medicine, UNSW Sydney, Sydney, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2019.02.010DOI Listing
June 2019

Signal Transducer and Activator of Transcription 3 Control of Human T and B Cell Responses.

Front Immunol 2018 7;9:168. Epub 2018 Feb 7.

Immunology Division, Garvan Institute of Medical Research, Darlinghurst, NSW, Australia.

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http://dx.doi.org/10.3389/fimmu.2018.00168DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5810249PMC
March 2019

Immune Dysregulation and Disease Pathogenesis due to Activating Mutations in PIK3CD-the Goldilocks' Effect.

J Clin Immunol 2019 02 25;39(2):148-158. Epub 2019 Mar 25.

Immunology, Garvan Institute of Medical Research, 384 Victoria St, Darlinghurst, NSW, 2010, Australia.

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http://dx.doi.org/10.1007/s10875-019-00612-9DOI Listing
February 2019

Activating PIK3CD mutations impair human cytotoxic lymphocyte differentiation and function and EBV immunity.

J Allergy Clin Immunol 2019 01 22;143(1):276-291.e6. Epub 2018 May 22.

Immunology Division, Garvan Institute of Medical Research, Darlinghurst, Australia; St Vincent's Clinical School, Faculty of Medicine, University of New South Wales Sydney, Darlinghurst, Australia; CIRCA (Clinical Immunogenomics Consortia Australia), Sydney, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2018.04.030DOI Listing
January 2019

Cytokine-Mediated Regulation of Human Lymphocyte Development and Function: Insights from Primary Immunodeficiencies.

J Immunol 2017 09;199(6):1949-1958

Immunology Division, Garvan Institute of Medical Research, Darlinghurst, New South Wales 2010, Australia; and.

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http://dx.doi.org/10.4049/jimmunol.1700842DOI Listing
September 2017

The TORC that Gets the GC Cycling.

Immunity 2017 06;46(6):974-976

Immunology Research Program, Garvan Institute of Medical Research, Darlinghurst, NSW, Australia; St. Vincent's Clinical School, University of New South Wales, Darlinghurst, NSW, Australia.

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http://dx.doi.org/10.1016/j.immuni.2017.06.003DOI Listing
June 2017

The circulating life of a memory T-follicular helper cell.

Clin Transl Immunology 2017 May 19;6(5):e141. Epub 2017 May 19.

Immunology Division, Garvan Institute of Medical Research Darlinghurst, NSW, Australia.

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http://dx.doi.org/10.1038/cti.2017.17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5493586PMC
May 2017

Erratum: The circulating life of a memory T-follicular helper cell.

Clin Transl Immunology 2017 May 26;6(5):e145. Epub 2017 May 26.

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http://dx.doi.org/10.1038/cti.2017.26DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5493590PMC
May 2017

B-cell-specific STAT3 deficiency: Insight into the molecular basis of autosomal-dominant hyper-IgE syndrome.

J Allergy Clin Immunol 2016 11 11;138(5):1455-1458.e3. Epub 2016 Jun 11.

Immunology Division, Garvan Institute of Medical Research, Darlinghurst, Australia; St Vincent's Clinical School, UNSW Australia, Darlinghurst, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2016.05.018DOI Listing
November 2016

Elucidating the effects of disease-causing mutations on STAT3 function in autosomal-dominant hyper-IgE syndrome.

J Allergy Clin Immunol 2016 10 13;138(4):1210-1213.e5. Epub 2016 May 13.

Immunology Research Program, Garvan Institute of Medical Research, Darlinghurst, Australia; St Vincent's Clinical School, University of New South Wales Australia, Darlinghurst, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2016.04.020DOI Listing
October 2016

T follicular helper cells have distinct modes of migration and molecular signatures in naive and memory immune responses.

Immunity 2015 Apr 31;42(4):704-18. Epub 2015 Mar 31.

Garvan Institute of Medical Research, 384 Victoria Street, Darlinghurst, NSW 2010, Australia; St Vincent's Clinical School, Faculty of Medicine, UNSW Australia, 390 Victoria Street, Darlinghurst, NSW 2010, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.immuni.2015.03.002DOI Listing
April 2015

STAT3 is a central regulator of lymphocyte differentiation and function.

Curr Opin Immunol 2014 Jun 6;28:49-57. Epub 2014 Mar 6.

Immunology and Immunodeficiency Group, Immunology Research Program, Garvan Institute of Medical Research, Darlinghurst, NSW, Australia; St Vincent's Clinical School, University of New South Wales, Darlinghurst, NSW, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.coi.2014.01.015DOI Listing
June 2014

Human T follicular helper (Tfh) cells and disease.

Immunol Cell Biol 2014 Jan 22;92(1):64-71. Epub 2013 Oct 22.

1] Immunology Program, Garvan Institute of Medical Research, Darlinghurst, New South Wales, Australia [2] St Vincent's Clinical School, University of New South Wales, Kensington, New South Wales, Australia.

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http://dx.doi.org/10.1038/icb.2013.55DOI Listing
January 2014

The good, the bad and the ugly - TFH cells in human health and disease.

Nat Rev Immunol 2013 Jun 17;13(6):412-26. Epub 2013 May 17.

Immunology Research Program, Garvan Institute of Medical Research, Darlinghurst, Sydney, New South Wales 2010, Australia.

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http://dx.doi.org/10.1038/nri3447DOI Listing
June 2013

The origins, function, and regulation of T follicular helper cells.

J Exp Med 2012 Jul;209(7):1241-53

Immunology Program, Garvan Institute of Medical Research, Darlinghurst, NSW 2010, Australia.

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http://dx.doi.org/10.1084/jem.20120994DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3405510PMC
July 2012

T cell-B cell interactions in primary immunodeficiencies.

Ann N Y Acad Sci 2012 Feb 30;1250:1-13. Epub 2012 Jan 30.

Garvan Institute of Medical Research, Darlinghurst, NSW, Australia.

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http://dx.doi.org/10.1111/j.1749-6632.2011.06361.xDOI Listing
February 2012

The regulation and role of T follicular helper cells in immunity.

Immunology 2011 Dec;134(4):361-7

Immunology Program, Garvan Institute of Medical Research, Darlinghurst, NSW, Australia.

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http://doi.wiley.com/10.1111/j.1365-2567.2011.03487.x
Publisher Site
http://dx.doi.org/10.1111/j.1365-2567.2011.03487.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3230790PMC
December 2011

Regulation of T follicular helper cell formation and function by antigen presenting cells.

Curr Opin Immunol 2011 Feb 4;23(1):111-8. Epub 2010 Nov 4.

Immunology Program, Garvan Institute of Medical Research, 384 Victoria Street, Darlinghurst, 2010, NSW, Australia.

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http://dx.doi.org/10.1016/j.coi.2010.10.007DOI Listing
February 2011

The role of SAP and SLAM family molecules in the humoral immune response.

Ann N Y Acad Sci 2011 Jan 22;1217:32-44. Epub 2010 Nov 22.

Immunology Program, Garvan Institute of Medical Research, Darlinghurst, NSW, Australia.

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http://dx.doi.org/10.1111/j.1749-6632.2010.05824.xDOI Listing
January 2011

Human Th9 cells: inflammatory cytokines modulate IL-9 production through the induction of IL-21.

Immunol Cell Biol 2010 Aug 8;88(6):621-3. Epub 2010 Jun 8.

Immunology Program, Garvan Institute of Medical Research, Darlinghurst, New South Wales, Australia.

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http://doi.wiley.com/10.1038/icb.2010.73
Publisher Site
http://dx.doi.org/10.1038/icb.2010.73DOI Listing
August 2010

c-Rel phenocopies PKCtheta but not Bcl-10 in regulating CD8+ T-cell activation versus tolerance.

Eur J Immunol 2010 Mar;40(3):867-77

Campbell Family Institute, Ontario Cancer Institute, University of Toronto, Toronto, ON, Canada.

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http://dx.doi.org/10.1002/eji.200939445DOI Listing
March 2010

c-Rel but not NF-kappaB1 is important for T regulatory cell development.

Eur J Immunol 2010 Mar;40(3):677-81

Campbell Family Institute for Breast Cancer Research, Ontario Cancer Institute, Toronto, Ont., Canada.

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http://dx.doi.org/10.1002/eji.201040298DOI Listing
March 2010

Immunology: Helpful T cells are sticky.

Nature 2008 Oct;455(7214):745-7

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http://dx.doi.org/10.1038/455745aDOI Listing
October 2008

The sound of silence: modulating anergy in T lymphocytes.

Curr Opin Immunol 2007 Dec 18;19(6):658-64. Epub 2007 Oct 18.

The Campbell Family Institute for Breast Cancer Research, University Health Network, Toronto, ON, Canada.

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http://dx.doi.org/10.1016/j.coi.2007.08.005DOI Listing
December 2007

Autoimmunity: IL-21: a new player in Th17-cell differentiation.

Immunol Cell Biol 2007 Oct 4;85(7):503-5. Epub 2007 Sep 4.

Immunology and Inflammation Program, Garvan Institute of Medical Research, 384 Victoria Street, Darlinghurst [corrected] Sydney, New South Wales [corrected] Australia.

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http://dx.doi.org/10.1038/sj.icb.7100114DOI Listing
October 2007

Decision criteria for resolving isotype switching conflicts by B cells.

Eur J Immunol 2005 Oct;35(10):2949-55

Immune Regulation Group, Centenary Institute of Cancer Medicine and Cell Biology, Newtown, Australia.

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http://dx.doi.org/10.1002/eji.200425719DOI Listing
October 2005

TCR affinity and negative regulation limit autoimmunity.

Nat Med 2004 Nov 3;10(11):1234-9. Epub 2004 Oct 3.

Institute for Breast Cancer Research, Ontario Cancer Institute, Departments of Medical Biophysics and Immunology, University of Toronto, Toronto, Ontario M5G 2C1, Canada.

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http://dx.doi.org/10.1038/nm1114DOI Listing
November 2004

PKCtheta signals activation versus tolerance in vivo.

J Exp Med 2004 Mar;199(6):743-52

Ontario Cancer Institute, University Health Network, 610 University Ave., Toronto, M5G 2M9 Canada.

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http://dx.doi.org/10.1084/jem.20031022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212730PMC
March 2004

Stochastic model of T cell proliferation: a calculus revealing IL-2 regulation of precursor frequencies, cell cycle time, and survival.

J Immunol 2003 May;170(10):4963-72

Immune Regulation Group, Centenary Institute of Cancer Medicine and Cell Biology, Newtown, New South Wales, Australia.

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http://dx.doi.org/10.4049/jimmunol.170.10.4963DOI Listing
May 2003

Intrinsic differences in the proliferation of naive and memory human B cells as a mechanism for enhanced secondary immune responses.

J Immunol 2003 Jan;170(2):686-94

Immune Regulation Group, Centenary Institute of Cancer Medicine and Cell Biology, Sydney, Australia.

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http://dx.doi.org/10.4049/jimmunol.170.2.686DOI Listing
January 2003