Elisio Costa

Elisio Costa

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Elisio Costa

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Next-generation Allergic Rhinitis and Its Impact on Asthma (ARIA) guidelines for allergic rhinitis based on Grading of Recommendations Assessment, Development and Evaluation (GRADE) and real-world evidence.

Authors:
Jean Bousquet Holger J Schünemann Akdis Togias Claus Bachert Martina Erhola Peter W Hellings Ludger Klimek Oliver Pfaar Dana Wallace Ignacio Ansotegui Ioana Agache Anna Bedbrook Karl-Christian Bergmann Mike Bewick Philippe Bonniaud Sinthia Bosnic-Anticevich Isabelle Bossé Jacques Bouchard Louis-Philippe Boulet Jan Brozek Guy Brusselle Moises A Calderon Walter G Canonica Luis Caraballo Vicky Cardona Thomas Casale Lorenzo Cecchi Derek K Chu Elisio M Costa Alvaro A Cruz Wienczyslawa Czarlewski Gennaro D'Amato Philippe Devillier Mark Dykewicz Motohiro Ebisawa Jean-Louis Fauquert Wytske J Fokkens Joao A Fonseca Jean-François Fontaine Bilun Gemicioglu Roy Gerth van Wijk Tari Haahtela Susanne Halken Despo Ierodiakonou Tomohisa Iinuma Juan-Carlos Ivancevich Marek Jutel Igor Kaidashev Musa Khaitov Omer Kalayci Jorg Kleine Tebbe Marek L Kowalski Piotr Kuna Violeta Kvedariene Stefania La Grutta Désirée Larenas-Linemann Susanne Lau Daniel Laune Lan Le Philipp Lieberman Karin C Lodrup Carlsen Olga Lourenço Gert Marien Pedro Carreiro-Martins Erik Melén Enrica Menditto Hugo Neffen Gregoire Mercier Ralph Mosgues Joaquim Mullol Antonella Muraro Leyla Namazova Ettore Novellino Robyn O'Hehir Yoshitaka Okamoto Ken Ohta Hae Sim Park Petr Panzner Giovanni Passalacqua Nhan Pham-Thi David Price Graham Roberts Nicolas Roche Christine Rolland Nelson Rosario Dermot Ryan Boleslaw Samolinski Mario Sanchez-Borges Glenis K Scadding Mohamed H Shamji Aziz Sheikh Ana-Maria Todo Bom Sanna Toppila-Salmi Ioana Tsiligianni Marylin Valentin-Rostan Arunas Valiulis Erkka Valovirta Maria-Teresa Ventura Samantha Walker Susan Waserman Arzu Yorgancioglu Torsten Zuberbier

J Allergy Clin Immunol 2019 Oct 15. Epub 2019 Oct 15.

Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Uniersität zu Berlin and Berlin Institute of Health, Comprehensive Allergy-Centre, Department of Dermatology and Allergy, member of GA(2)LEN, Berlin, Germany.

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http://dx.doi.org/10.1016/j.jaci.2019.06.049DOI Listing
October 2019

Next-generation ARIA care pathways for rhinitis and asthma: a model for multimorbid chronic diseases.

Authors:
J Jean Bousquet Holger J Schünemann Alkis Togias Marina Erhola Peter W Hellings Torsten Zuberbier Ioana Agache Ignacio J Ansotegui Josep M Anto Claus Bachert Sven Becker Martin Bedolla-Barajas Michael Bewick Sinthia Bosnic-Anticevich Isabelle Bosse Louis P Boulet Jean Marc Bourrez Guy Brusselle Niels Chavannes Elisio Costa Alvaro A Cruz Wienczyslawa Czarlewski Wytske J Fokkens Joao A Fonseca Mina Gaga Tari Haahtela Maddalena Illario Ludger Klimek Piotr Kuna Violeta Kvedariene L T T Le Desiree Larenas-Linnemann Daniel Laune Olga M Lourenço Enrica Menditto Joaquin Mullol Yashitaka Okamoto Nikos Papadopoulos Nhân Pham-Thi Robert Picard Hilary Pinnock Nicolas Roche Regina E Roller-Wirnsberger Christine Rolland Boleslaw Samolinski Aziz Sheikh Sanna Toppila-Salmi Ioanna Tsiligianni Arunas Valiulis Erkka Valovirta Tuula Vasankari Maria-Teresa Ventura Samantha Walker Sian Williams Cezmi A Akdis Isabella Annesi-Maesano Sylvie Arnavielhe Xavier Basagana Eric Bateman Anna Bedbrook K S Bennoor Samuel Benveniste Karl C Bergmann Slawomir Bialek Nils Billo Carsten Bindslev-Jensen Leif Bjermer Hubert Blain Mateo Bonini Philippe Bonniaud Jacques Bouchard Vitalis Briedis Christofer E Brightling Jan Brozek Roland Buhl Roland Buonaiuto Giorgo W Canonica Victoria Cardona Ana M Carriazo Warner Carr Christine Cartier Thomas Casale Lorenzo Cecchi Alfonso M Cepeda Sarabia Eka Chkhartishvili Derek K Chu Cemal Cingi Elaine Colgan Jaime Correia de Sousa Anne Lise Courbis Adnan Custovic Biljana Cvetkosvki Gennaro D'Amato Jane da Silva Carina Dantas Dejand Dokic Yves Dauvilliers Antoni Dedeu Giulia De Feo Philippe Devillier Stefania Di Capua Marc Dykewickz Ruta Dubakiene Motohiro Ebisawa Yaya El-Gamal Esben Eller Regina Emuzyte John Farrell Antjie Fink-Wagner Alessandro Fiocchi Jean F Fontaine Bilun Gemicioğlu Peter Schmid-Grendelmeir Amiran Gamkrelidze Judith Garcia-Aymerich Maximiliano Gomez Sandra González Diaz Maia Gotua Nick A Guldemond Maria-Antonieta Guzmán Jawad Hajjam John O'B Hourihane Marc Humbert Guido Iaccarino Despo Ierodiakonou Maddalena Illario Juan C Ivancevich Guy Joos Ki-Suck Jung Marek Jutel Igor Kaidashev Omer Kalayci Przemyslaw Kardas Thomas Keil Mussa Khaitov Nikolai Khaltaev Jorg Kleine-Tebbe Marek L Kowalski Vicky Kritikos Inger Kull Lisa Leonardini Philip Lieberman Brian Lipworth Karin C Lodrup Carlsen Claudia C Loureiro Renaud Louis Alpana Mair Gert Marien Bassam Mahboub Joao Malva Patrick Manning Esteban De Manuel Keenoy Gailen D Marshall Mohamed R Masjedi Jorge F Maspero Eve Mathieu-Dupas Poalo M Matricardi Eric Melén Elisabete Melo-Gomes Eli O Meltzer Enrica Menditto Jacques Mercier Neven Miculinic Florin Mihaltan Branislava Milenkovic Giuliana Moda Maria-Dolores Mogica-Martinez Yousser Mohammad Steve Montefort Ricardo Monti Mario Morais-Almeida Ralf Mösges Lars Münter Antonella Muraro Ruth Murray Robert Naclerio Luigi Napoli Leila Namazova-Baranova Hugo Neffen Kristoff Nekam Angelo Neou Enrico Novellino Dieudonné Nyembue Robin O'Hehir Ken Ohta Kimi Okubo Gabrielle Onorato Solange Ouedraogo Isabella Pali-Schöll Susanna Palkonen Peter Panzner Hae-Sim Park Jean-Louis Pépin Ana-Maria Pereira Oliver Pfaar Ema Paulino Jim Phillips Robert Picard Davor Plavec Ted A Popov Fabienne Portejoie David Price Emmanuel P Prokopakis Benoit Pugin Filip Raciborski Rojin Rajabian-Söderlund Sietze Reitsma Xavier Rodo Antonino Romano Nelson Rosario Menahenm Rottem Dermot Ryan Johanna Salimäki Mario M Sanchez-Borges Juan-Carlos Sisul Dirceu Solé David Somekh Talant Sooronbaev Milan Sova Otto Spranger Cristina Stellato Rafael Stelmach Charlotte Suppli Ulrik Michel Thibaudon Teresa To Ana Todo-Bom Peter V Tomazic Antonio A Valero Rudolph Valenta Marylin Valentin-Rostan Rianne van der Kleij Olivier Vandenplas Giorgio Vezzani Frédéric Viart Giovanni Viegi Dana Wallace Martin Wagenmann De Y Wang Susan Waserman Magnus Wickman Dennis M Williams Gary Wong Piotr Wroczynski Panayiotis K Yiallouros Arzu Yorgancioglu Osman M Yusuf Heahter J Zar Stéphane Zeng Mario Zernotti Luo Zhang Nan S Zhong Mihaela Zidarn

Clin Transl Allergy 2019 9;9:44. Epub 2019 Sep 9.

260University Clinic of Respiratory and Allergic Diseases, Golnik, Slovenia.

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http://dx.doi.org/10.1186/s13601-019-0279-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6734297PMC
September 2019

A Microfluidic Deformability Assessment of Pathological Red Blood Cells Flowing in a Hyperbolic Converging Microchannel.

Micromachines (Basel) 2019 Sep 25;10(10). Epub 2019 Sep 25.

MEtRICs, Mechanical Engineering Department, University of Minho, Campus de Azurém, 4800-058 Guimarães, Portugal.

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http://dx.doi.org/10.3390/mi10100645DOI Listing
September 2019

Prevalence of frailty status among the European elderly population: Findings from the Survey of Health, Aging and Retirement in Europe.

Geriatr Gerontol Int 2019 Aug 30;19(8):723-729. Epub 2019 May 30.

UCIBIO REQUIMTE, Porto4Ageing and Faculty of Pharmacy, University of Porto, Porto, Portugal.

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http://dx.doi.org/10.1111/ggi.13689DOI Listing
August 2019

Next-generation care pathways for allergic rhinitis and asthma multimorbidity: a model for multimorbid non-communicable diseases-Meeting Report (Part 1).

J Thorac Dis 2019 Aug;11(8):3633-3642

Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Uniersität zu Berlin and Berlin Institute of Health, Comprehensive Allergy-Centre, Department of Dermatology and Allergy, Member of GA2LEN, Berlin, Germany.

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http://dx.doi.org/10.21037/jtd.2019.08.64DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6753463PMC
August 2019

ARIA pharmacy 2018 "Allergic rhinitis care pathways for community pharmacy": AIRWAYS ICPs initiative (European Innovation Partnership on Active and Healthy Ageing, DG CONNECT and DG Santé) POLLAR (Impact of Air POLLution on Asthma and Rhinitis) GARD Demonstration project.

Authors:
Sinthia Bosnic-Anticevich Elisio Costa Enrica Menditto Olga Lourenço Ettore Novellino Slawomir Bialek Vitalis Briedis Roland Buonaiuto Henry Chrystyn Biljana Cvetkovski Stefania Di Capua Vicky Kritikos Alpana Mair Valentina Orlando Ema Paulino Johanna Salimäki Rojin Söderlund Rachel Tan Dennis M Williams Piotr Wroczynski Ioana Agache Ignacio J Ansotegui Josep M Anto Anna Bedbrook Claus Bachert Mike Bewick Carsten Bindslev-Jensen Jan L Brozek Giorgio Walter Canonica Victoria Cardona Warner Carr Thomas B Casale Niels H Chavannes Jaime Correia de Sousa Alvaro A Cruz Wienczyslawa Czarlewski Giuseppe De Carlo Pascal Demoly Philippe Devillier Mark S Dykewicz Mina Gaga Yehia El-Gamal João Fonseca Wytske J Fokkens Maria Antonieta Guzmán Tari Haahtela Peter W Hellings Maddalena Illario Juan Carlos Ivancevich Jocelyne Just Igor Kaidashev Musa Khaitov Nikolai Khaltaev Thomas Keil Ludger Klimek Marek L Kowalski Piotr Kuna Violeta Kvedariene Désirée E Larenas-Linnemann Daniel Laune Lan T T Le Karin C Lodrup Carlsen Bassam Mahboub Dieter Maier Joao Malva Patrick J Manning Mário Morais-Almeida Ralph Mösges Joaquim Mullol Lars Münter Ruth Murray Robert Naclerio Leyla Namazova-Baranova Kristof Nekam Tshipukane Dieudonné Nyembue Kimi Okubo Robyn E O'Hehir Ken Ohta Yoshitaka Okamoto Gabrielle L Onorato Susanna Palkonen Petr Panzner Nikolaos G Papadopoulos Hae-Sim Park Ruby Pawankar Oliver Pfaar Jim Phillips Davor Plavec Todor A Popov Paul C Potter Emmanuel P Prokopakis Regina E Roller-Wirnsberger Menachem Rottem Dermot Ryan Bolesław Samolinski Mario Sanchez-Borges Holger J Schunemann Aziz Sheikh Juan Carlos Sisul David Somekh Cristiana Stellato Teresa To Ana Maria Todo-Bom Peter Valentin Tomazic Sanna Toppila-Salmi Antonio Valero Arunas Valiulis Errka Valovirta Maria Teresa Ventura Martin Wagenmann Dana Wallace Susan Waserman Magnus Wickman Panayiotis K Yiallouros Arzu Yorgancioglu Osman M Yusuf Heather J Zar Mario E Zernotti Luo Zhang Mihaela Zidarn Torsten Zuberbier Jean Bousquet

Allergy 2019 Jul 30;74(7):1219-1236. Epub 2019 Apr 30.

MACVIA-France, Fondation Partenariale FMC VIA-LR, Montpellier, France.

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http://dx.doi.org/10.1111/all.13701DOI Listing
July 2019

Mobile technology offers novel insights into the control and treatment of allergic rhinitis: The MASK study.

J Allergy Clin Immunol 2019 Jul 3;144(1):135-143.e6. Epub 2019 Apr 3.

MACVIA-France, Fondation partenariale FMC VIA-LR, Montpellier, France; University Hospital, Montpellier, France; INSERM U 1168, VIMA: Ageing and chronic diseases Epidemiological and Public Health Approaches, Villejuif, Université Versailles St-Quentin-en-Yvelines, Montigny le Bretonneux, and Euforea, Brussels, Belgium. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2019.01.053DOI Listing
July 2019

Social support and treatment adherence in patients with end-stage renal disease: A systematic review.

Semin Dial 2019 Jul 15. Epub 2019 Jul 15.

School of Health Sciences, University of Aveiro (ESSUA), Aveiro, Portugal.

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http://dx.doi.org/10.1111/sdi.12831DOI Listing
July 2019

Dairy Product Intake in Older Adults across Europe Based On the SHARE Database.

J Nutr Gerontol Geriatr 2019 Jul-Sep;38(3):297-306. Epub 2019 Jun 22.

a UCIBIO/REQUINTE, Faculty of Pharmacy , Porto.

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http://dx.doi.org/10.1080/21551197.2019.1627972DOI Listing
June 2019

Polypharmacy prevalence among older adults based on the survey of health, ageing and retirement in Europe.

Arch Gerontol Geriatr 2018 Sep - Oct;78:213-220. Epub 2018 Jun 30.

UCIBIO, REQUIMTE and Faculty of Pharmacy, University of Porto, Porto, Portugal. Electronic address:

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http://dx.doi.org/10.1016/j.archger.2018.06.018DOI Listing
April 2019

2019 ARIA Care pathways for allergen immunotherapy.

Authors:
Jean Bousquet Oliver Pfaar Alkis Togias Holger J Schünemann Ignacio Ansotegui Nikolaos G Papadopoulos Ioanna Tsiligianni Ioana Agache Josep M Anto Claus Bachert Anna Bedbrook Karl-Christian Bergmann Sinthia Bosnic-Anticevich Isabelle Bosse Jan Brozek Moises A Calderon Giorgio W Canonica Luigi Caraballo Victoria Cardona Thomas Casale Lorenzo Cecchi Derek Chu Elisio Costa Alvaro A Cruz Wienczyslawa Czarlewski Stephen R Durham George Du Toit Mark Dykewicz Motohiro Ebisawa Jean Luc Fauquert Montserrat Fernandez-Rivas Wytske J Fokkens João Fonseca Jean-François Fontaine Roy Gerth van Wijk Tari Haahtela Susanne Halken Peter W Hellings Despo Ierodiakonou Tomohisa Iinuma Juan Carlos Ivancevich Lars Jacobsen Marek Jutel Igor Kaidashev Musa Khaitov Omer Kalayci Jörg Kleine Tebbe Ludger Klimek Marek L Kowalski Piotr Kuna Violeta Kvedariene Stefania La Grutta Désirée Larenas-Linemann Susanne Lau Daniel Laune Lan Le Karin Lodrup Carlsen Olga Lourenço Hans-Jørgen Malling Gert Marien Enrica Menditto Gregoire Mercier Joaquim Mullol Antonella Muraro Robyn O'Hehir Yoshitaka Okamoto Giovanni B Pajno Hae-Sim Park Petr Panzner Giovanni Passalacqua Nhan Pham-Thi Graham Roberts Ruby Pawankar Christine Rolland Nelson Rosario Dermot Ryan Bolesław Samolinski Mario Sanchez-Borges Glenis Scadding Mohamed H Shamji Aziz Sheikh Gunter J Sturm Ana Todo Bom Sanna Toppila-Salmi Maryline Valentin-Rostan Arunas Valiulis Erkka Valovirta Maria-Teresa Ventura Ulrich Wahn Samantha Walker Dana Wallace Susan Waserman Arzu Yorgancioglu Torsten Zuberbier

Allergy 2019 Apr 7. Epub 2019 Apr 7.

Department of Dermatology and Allergy, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Berlin Institute of Health, Comprehensive Allergy Centre, Member of GA2LEN, Humboldt-Uniersität zu Berlin, Berlin, Germany.

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http://dx.doi.org/10.1111/all.13805DOI Listing
April 2019

Allergic Rhinitis and its Impact on Asthma (ARIA) Phase 4 (2018): Change management in allergic rhinitis and asthma multimorbidity using mobile technology.

Authors:
Jean Bousquet Peter W Hellings Ioana Agache Flore Amat Isabella Annesi-Maesano Ignacio J Ansotegui Josep M Anto Claus Bachert Eric D Bateman Anna Bedbrook Kazi Bennoor Mickael Bewick Carsten Bindslev-Jensen Sinthia Bosnic-Anticevich Isabelle Bosse Jan Brozek Luisa Brussino Giorgio W Canonica Victoria Cardona Thomas Casale Alfonso M Cepeda Sarabia Niels H Chavannes Lorenzo Cecchi Jaime Correia de Sousa Elisio Costa Alvaro A Cruz Wienczyslawa Czarlewski Giuseppe De Carlo Giulia De Feo Pascal Demoly Philippe Devillier Mark S Dykewicz Yehia El-Gamal Esben E Eller Joao A Fonseca Jean-François Fontaine Wytske J Fokkens Maria-Antonieta Guzmán Tari Haahtela Maddalena Illario Juan-Carlos Ivancevich Jocelyne Just Igor Kaidashev Musa Khaitov Omer Kalayci Thomas Keil Ludger Klimek Marek L Kowalski Piotr Kuna Violeta Kvedariene Desiree Larenas-Linnemann Daniel Laune Lan T T Le Karin Lodrup Carlsen Olga Lourenço Bassam Mahboub Alpana Mair Enrica Menditto Branislava Milenkovic Mario Morais-Almeida Ralph Mösges Joaquim Mullol Ruth Murray Robert Naclerio Leyla Namazova-Baranova Ettore Novellino Robyn E O'Hehir Ken Ohta Yoshitaka Okamoto Kimi Okubo Gabrielle L Onorato Susanna Palkonen Petr Panzner Nikos G Papadopoulos Hae-Sim Park Ema Paulino Ruby Pawankar Oliver Pfaar Davor Plavec Ted A Popov Paul Potter Emmanuel P Prokopakis Menachem Rottem Dermot Ryan Johanna Salimäki Boleslaw Samolinski Mario Sanchez-Borges Holger J Schunemann Aziz Sheikh Juan-Carlos Sisul Rojin Rajabian-Söderlund Talant Sooronbaev Cristiana Stellato Teresa To Ana-Maria Todo-Bom Peter-Valentin Tomazic Sanna Toppila-Salmi Antonio Valero Arunas Valiulis Erkka Valovirta Maria-Teresa Ventura Martin Wagenmann De Yun Wang Dana Wallace Susan Waserman Magnus Wickman Arzu Yorgancioglu Luo Zhang Nanshan Zhong Mihaela Zidarn Torsten Zuberbier

J Allergy Clin Immunol 2019 Mar 29;143(3):864-879. Epub 2018 Sep 29.

Comprehensive Allergy Center Charité, Department of Dermatology and Allergy, Charité-Universitätsmedizin Berlin, and Global Allergy and Asthma European Network (GA2LEN), Berlin, Germany.

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http://dx.doi.org/10.1016/j.jaci.2018.08.049DOI Listing
March 2019

Nutritional, chemical and antioxidant/pro-oxidant profiles of silverskin, a coffee roasting by-product.

Food Chem 2018 Nov 21;267:28-35. Epub 2017 Mar 21.

REQUIMTE/LAQV, Department of Chemical Sciences, Faculty of Pharmacy of University of Porto, R. Jorge Viterbo Ferreira, 228, 4050-313 Porto, Portugal. Electronic address:

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http://dx.doi.org/10.1016/j.foodchem.2017.03.106DOI Listing
November 2018

A cornerstone of healthy aging: do we need to rethink the concept of adherence in the elderly?

Patient Prefer Adherence 2018 11;12:1003-1005. Epub 2018 Jun 11.

Elísio Costa, UCIBIO-REQUIMTE, Faculty of Pharmacy and Porto4Ageing EIP-AHA Reference Site, University of Porto, Porto, Portugal.

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http://dx.doi.org/10.2147/PPA.S164686DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6001841PMC
June 2018

Long term performance evaluation of small-diameter vascular grafts based on polyvinyl alcohol hydrogel and dextran and MSCs-based therapies using the ovine pre-clinical animal model.

Int J Pharm 2017 May 7;523(2):515-530. Epub 2017 Mar 7.

Centro de Estudos de Ciência Animal (CECA), Instituto de Ciências, Tecnologias e Agroambiente da Universidade do Porto (ICETA), Praça Gomes Teixeira, Apartado 55142, 4051-401 Porto, Portugal; Departamento de Clínicas Veterinárias, Instituto de Ciências Biomédicas de Abel Salazar (ICBAS), Universidade do Porto (UP), Rua de Jorge Viterbo Ferreira, n° 228, 4050-313 Porto, Portugal. Electronic address:

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http://dx.doi.org/10.1016/j.ijpharm.2017.02.043DOI Listing
May 2017

Clinical practices among healthcare professionals concerning neonatal jaundice and pale stools.

Eur J Pediatr 2017 Mar 12;176(3):361-369. Epub 2017 Jan 12.

Gastroenterology Unit, Paediatrics Department, Hospital de Santa Maria, Centro Hospitalar Lisboa Norte, Av. Prof. Egas Moniz, 1600-190, Lisboa, Portugal.

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http://dx.doi.org/10.1007/s00431-016-2847-yDOI Listing
March 2017

End-stage renal disease adherence questionnaire: translation and validation to the portuguese language.

Ren Fail 2016 Nov 20;38(10):1633-1638. Epub 2016 Oct 20.

g Department of Biological Sciences, Faculty of Pharmacy , University of Porto , Porto , Portugal.

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http://dx.doi.org/10.1080/0886022X.2016.1209063DOI Listing
November 2016

Long term performance evaluation of small-diameter vascular grafts based on polyvinyl alcohol hydrogel and dextran and MSCs-based therapies using the ovine pre-clinical animal model.

Int J Pharm 2016 Nov 14;513(1-2):332-346. Epub 2016 Sep 14.

Centro de Estudos de Ciência Animal (CECA), Instituto de Ciências, Tecnologias e Agroambiente da Universidade do Porto (ICETA), Praça Gomes Teixeira, Apartado 55142, 4051-401, Porto, Portugal; Departamento de Clínicas Veterinárias, Instituto de Ciências Biomédicas de Abel Salazar (ICBAS), Universidade do Porto (UP), Rua de Jorge Viterbo Ferreira, n° 228, 4050-313 Porto, Portugal.

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http://dx.doi.org/10.1016/j.ijpharm.2016.09.045DOI Listing
November 2016

Different hydroxyapatite magnetic nanoparticles for medical imaging: Its effects on hemostatic, hemolytic activity and cellular cytotoxicity.

Colloids Surf B Biointerfaces 2016 Oct 25;146:363-74. Epub 2016 Jun 25.

i3S- Instituto de Investigação e Inovação em Saúde, Universidade do Porto, Portugal; INEB- Instituto de Engenharia Biomédica, Divisão de Biomateriais, Universidade do Porto, Portugal; Faculdade de Engenharia, DEMM, Universidade do Porto, Portugal.

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http://dx.doi.org/10.1016/j.colsurfb.2016.06.042DOI Listing
October 2016

Interventional Tools to Improve Prescription and Adherence to Medical Plans.

Biomed Res Int 2015 24;2015:602078. Epub 2015 Nov 24.

Department of Clinical and Experimental Sciences, University of Brescia, Viale Europa 11, 25123 Brescia, Italy.

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http://dx.doi.org/10.1155/2015/602078DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4672111PMC
September 2016

Recombinant human erythropoietin-induced erythropoiesis regulates hepcidin expression over iron status in the rat.

Blood Cells Mol Dis 2016 07 19;59:63-70. Epub 2016 Apr 19.

Research Unit on Applied Molecular Biosciences (UCIBIO), REQUIMTE, Department of Biological Sciences, Laboratory of Biochemistry, Faculty of Pharmacy, University of Porto, Porto, Portugal. Electronic address:

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http://dx.doi.org/10.1016/j.bcmd.2016.04.008DOI Listing
July 2016

Pathological and molecular mechanisms underlying resistance to recombinant human erythropoietin therapy in the remnant kidney rat model of chronic kidney disease associated anemia.

Biochimie 2016 Jun 31;125:150-62. Epub 2016 Mar 31.

Research Unit on Applied Molecular Biosciences (UCIBIO), REQUIMTE, Department of Biological Sciences, Laboratory of Biochemistry, Faculty of Pharmacy, University of Porto, Porto, Portugal. Electronic address:

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http://dx.doi.org/10.1016/j.biochi.2016.03.012DOI Listing
June 2016

Scaling up health knowledge at European level requires sharing integrated data: an approach for collection of database specification.

Clinicoecon Outcomes Res 2016 13;8:253-65. Epub 2016 Jun 13.

EpiChron Research Group on Chronic Diseases, Aragón Health Sciences Institute (IACS), IIS Aragón REDISSEC ISCIII, Miguel Servet University Hospital, University of Zaragoza, Zaragoza, Spain.

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http://dx.doi.org/10.2147/CEOR.S97548DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4912318PMC
June 2016

Liver iron is a major regulator of hepcidin gene expression via BMP/SMAD pathway in a rat model of chronic renal failure under treatment with high rHuEPO doses.

Biofactors 2016 May 18;42(3):296-306. Epub 2016 Mar 18.

Research Unit on Applied Molecular Biosciences (UCIBIO), REQUIMTE, Department of Biological Sciences, Laboratory of Biochemistry, Faculty of Pharmacy, University of Porto, Porto, Portugal.

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http://dx.doi.org/10.1002/biof.1275DOI Listing
May 2016

Predictors of Difficulty in Medication Intake in Europe: a Cross-country Analysis Based on SHARE.

Aging Dis 2016 May 27;7(3):246-53. Epub 2016 May 27.

5UCIBIO, REQUIMTE and Faculty of Pharmacy, University of Porto, Porto, Portugal.

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http://dx.doi.org/10.14336/AD.2015.0925DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4898921PMC
May 2016

Impaired renal endothelial nitric oxide synthase and reticulocyte production as modulators of hypertension induced by rHuEPO in the rat.

Life Sci 2016 Apr 27;151:147-156. Epub 2016 Feb 27.

Research Unit on Applied Molecular Biosciences (UCIBIO), REQUIMTE, Department of Biological Sciences, Laboratory of Biochemistry, Faculty of Pharmacy, University of Porto, Porto, Portugal. Electronic address:

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http://dx.doi.org/10.1016/j.lfs.2016.02.088DOI Listing
April 2016

Polymorphisms of the ELANE Gene Promoter Region in End-Stage Chronic Kidney Disease Patients.

Genes (Basel) 2016 Apr 29;7(5). Epub 2016 Apr 29.

UCIBIO/REQUIMTE, Laboratório de Bioquímica, Departamento de Ciências Biológicas, Faculdade de Farmácia, Universidade do Porto,4050-313 Porto, Portugal.

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http://dx.doi.org/10.3390/genes7050017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4880837PMC
April 2016

Iron-hepcidin dysmetabolism, anemia and renal hypoxia, inflammation and fibrosis in the remnant kidney rat model.

PLoS One 2015 13;10(4):e0124048. Epub 2015 Apr 13.

Laboratory of Pharmacology & Experimental Therapeutics, Institute for Biomedical Imaging and Life Sciences (IBILI), Faculty of Medicine, University of Coimbra, Coimbra, Portugal; Center for Neuroscience and Cell Biology-Institute for Biomedical Imaging and Life Sciences (CNC.IBILI) Research Unit, University of Coimbra, Coimbra, Portugal.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0124048PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4395008PMC
March 2016

Renal risk-benefit determinants of recombinant human erythropoietin therapy in the remnant kidney rat model - hypertension, anaemia, inflammation and drug dose.

Clin Exp Pharmacol Physiol 2016 Mar;43(3):343-54

Research Unit on Applied Molecular Biosciences (UCIBIO), REQUIMTE, Department of Biological Sciences, Laboratory of Biochemistry, Faculty of Pharmacy, University of Porto, Porto, Portugal.

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http://dx.doi.org/10.1111/1440-1681.12541DOI Listing
March 2016

Aging and cardiovascular risk.

Biomed Res Int 2015 2;2015:871656. Epub 2015 Mar 2.

Institute of Biomedicine (IBIOMED), University of León, Campus Universitario, 24071 León, Spain.

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http://dx.doi.org/10.1155/2015/871656DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4363687PMC
December 2015

Performance of In Silico Tools for the Evaluation of UGT1A1 Missense Variants.

Hum Mutat 2015 Dec 5;36(12):1215-25. Epub 2015 Oct 5.

UCIBIO/REQUIMTE, Laboratório de Bioquímica, Departamento de Ciências Biológicas, Faculdade de Farmácia, Universidade do Porto, Porto, Portugal.

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http://dx.doi.org/10.1002/humu.22903DOI Listing
December 2015

Resistance to Recombinant Human Erythropoietin Therapy in a Rat Model of Chronic Kidney Disease Associated Anemia.

Int J Mol Sci 2015 Dec 25;17(1). Epub 2015 Dec 25.

Laboratory of Pharmacology & Experimental Therapeutics, Institute for Biomedical Imaging and Life Sciences (IBILI), Faculty of Medicine, University of Coimbra, 3000-548 Coimbra, Portugal.

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http://dx.doi.org/10.3390/ijms17010028DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4730274PMC
December 2015

Interventional tools to improve medication adherence: review of literature.

Patient Prefer Adherence 2015 14;9:1303-14. Epub 2015 Sep 14.

Department of Clinical and Experimental Science, University of Brescia, Brescia, Italy.

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http://dx.doi.org/10.2147/PPA.S87551DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4576894PMC
September 2015

Potential cardiovascular risk protection of bilirubin in end-stage renal disease patients under hemodialysis.

Biomed Res Int 2014 10;2014:175286. Epub 2014 Sep 10.

Laboratório de Bioquímica, Departamento de Ciências Biológicas, Faculdade Farmácia, Universidade do Porto, Rua Jorge Viterbo Ferreira 228, 4050-313 Porto, Portugal ; Instituto de Biologia Molecular e Celular (IBMC), Universidade do Porto, Rua do Campo Alegre 823, 4150-180 Porto, Portugal.

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http://dx.doi.org/10.1155/2014/175286DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4174976PMC
June 2015

Bilirubin is independently associated with oxidized LDL levels in young obese patients.

Diabetol Metab Syndr 2015 23;7. Epub 2015 Jan 23.

Instituto de Biologia Molecular e Celular (Institute for Molecular and Cell Biology), Universidade do Porto, Porto, Portugal ; Instituto de Investigaçãoe Inovação em Saúde (Institute for Research and Innovation in Health), Universidade do Porto, Porto, Portugal ; Biological Science Department, Faculty of Pharmacy, University of Porto, Porto, Portugal ; Departamento de Ciências Biológicas, Faculdade de Farmácia da Universidade do Porto, Rua de Jorge Viterbo Ferreira, 228, Porto, 4050-313 Portugal.

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http://dx.doi.org/10.1186/1758-5996-7-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4429330PMC
May 2015

In vitro and in vivo evaluation of blood coagulation activation of polyvinyl alcohol hydrogel plus dextran-based vascular grafts.

J Biomed Mater Res A 2015 Apr 25;103(4):1366-79. Epub 2014 Jul 25.

Departamento de Zootecnia, Universidade de Évora, Pólo da Mitra, Apartado 94, 7002-554, Évora, Portugal; Instituto de Ciências Agro-ambientais Mediterrânicas (ICAAM), Pólo da Mitra, Apartado 94, 7002-554, Évora, Portugal.

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http://dx.doi.org/10.1002/jbm.a.35275DOI Listing
April 2015

Effect of Aging in the Perception of Health-Related Quality of Life in End-Stage Renal Disease Patients under Online-Hemodiafiltration.

Aging Dis 2015 Feb 25;6(1):17-26. Epub 2014 May 25.

Laboratório de Bioquímica, Departamento de Ciências Biológicas, Faculdade de Farmácia, Universidade do Porto, Portugal ; Instituto de Biologia Molecular e Celular, Universidade do Porto, Portugal.

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http://dx.doi.org/10.14336/AD.2014.0514DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4306470PMC
February 2015

Biochemical and cellular changes in leukocyte-depleted red blood cells stored for transfusion.

Transfus Med Hemother 2015 Jan 22;42(1):46-51. Epub 2014 Dec 22.

Departamento de Ciências Biológicas, Laboratório de Bioquímica, Faculdade Farmácia, Universidade do Porto, Porto, Portugal ; UCIBIO @ REQUIMTEUniversidade do Porto, Porto, Portugal.

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http://dx.doi.org/10.1159/000370140DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4404899PMC
January 2015

Biocompatibility and hemocompatibility of polyvinyl alcohol hydrogel used for vascular grafting--In vitro and in vivo studies.

J Biomed Mater Res A 2014 Dec 14;102(12):4262-75. Epub 2014 Feb 14.

Departamento de Zootecnia, Universidade de Évora (UE), Pólo da Mitra, Apartado 94, 7002-554, Évora, Portugal; Instituto de Ciências Agrárias e Ambientais Mediterrânicas (ICAAM), Universidade de Évora (UE), Pólo da Mitra, Apartado 94, 7002-554, Évora, Portugal.

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http://dx.doi.org/10.1002/jbm.a.35098DOI Listing
December 2014

Aging is Associated with Impaired Renal Function, INF-gamma Induced Inflammation and with Alterations in Iron Regulatory Proteins Gene Expression.

Aging Dis 2014 Dec 23;5(6):356-65. Epub 2013 Dec 23.

Laboratório de Bioquímica, Departamento de Ciências Biológicas, Faculdade de Farmácia, Universidade do Porto, Porto, Portugal ; Instituto de Biologia Molecular e Celular, Universidade do Porto, Porto, Portugal.

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http://dx.doi.org/10.14366/AD.2014.0500356DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4249806PMC
December 2014

Vascular access versus the effect of statins on inflammation and fibrinolysis in renal dialysis patients.

J Vasc Access 2013 Oct-Dec;14(4):335-41. Epub 2013 May 3.

FMC, Dinefro - Diálises e Nefrologia, SA - Portugal and Instituto de Ciências Biomédicas Abel Salazar (ICBAS), Universidade do Porto, Porto - Portugal.

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http://dx.doi.org/10.5301/jva.5000132DOI Listing
August 2014

Adiponectin and markers of metabolic syndrome in obese children and adolescents: impact of 8-mo regular physical exercise program.

Pediatr Res 2014 Aug 12;76(2):159-65. Epub 2014 May 12.

1] Biological Science Department, Faculty of Pharmacy, University of Oporto, Oporto, Portugal [2] Institute for Molecular and Cell Biology, University of Oporto, Oporto, Portugal.

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http://dx.doi.org/10.1038/pr.2014.73DOI Listing
August 2014

Risk factors for mortality in hemodialysis patients: two-year follow-up study.

Dis Markers 2013 24;35(6):791-8. Epub 2013 Nov 24.

Laboratório de Bioquímica, Departamento de Ciências Biológicas, Faculdade Farmácia, Universidade do Porto, Porto, Portugal ; Instituto de Biologia Molecular e Celular (IBMC), Universidade do Porto, Porto, Portugal ; Serviço de Bioquímica, Departamento de Ciências Biológicas, Faculdade de Farmácia, Universidade do Porto, Rua Jorge Viterbo Ferreira 228, 4050-313 Porto, Portugal.

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http://downloads.hindawi.com/journals/dm/2013/518945.pdf
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http://www.hindawi.com/journals/dm/2013/518945/
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http://dx.doi.org/10.1155/2013/518945DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3857718PMC
July 2014

Circulating cell-free DNA levels in hemodialysis patients and its association with inflammation, iron metabolism, and rhEPO doses.

Hemodial Int 2013 Oct 16;17(4):664-7. Epub 2013 May 16.

Departamento de Ciências Biológicas, Laboratório de Bioquímica, Faculdade de Farmácia, Universidade do Porto, Porto, Portugal; IBILI, Faculdade de Medicina, Universidade de Coimbra, Coimbra, Portugal.

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http://dx.doi.org/10.1111/hdi.12055DOI Listing
October 2013

Bilirubin levels and redox status in a young healthy population.

Acta Haematol 2013 6;130(1):57-60. Epub 2013 Mar 6.

Laboratório de Bioquímica, Departamento de Ciências Biológicas, Faculdade de Farmácia, Universidade do Porto, Porto, Portugal.

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http://dx.doi.org/10.1159/000346429DOI Listing
September 2013

Impact of UGT1A1 gene variants on total bilirubin levels in Gilbert syndrome patients and in healthy subjects.

Blood Cells Mol Dis 2012 Mar 9;48(3):166-72. Epub 2012 Feb 9.

Departamento de Ciências Biológicas, Laboratório de Bioquímica, Faculdade de Farmácia da Universidade do Porto, Portugal.

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http://dx.doi.org/10.1016/j.bcmd.2012.01.004DOI Listing
March 2012

Bilirubin dependence on UGT1A1 polymorphisms, hemoglobin, fasting time and body mass index.

Am J Med Sci 2012 Feb;343(2):114-118

Department of Biological Sciences, Biochemistry Laboratory, Faculty of Pharmacy of Oporto University, Porto; Institute for Cellular and Molecular Biology, Oporto University, Porto, Portugal. Electronic address:

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http://dx.doi.org/10.1097/MAJ.0b013e318223460fDOI Listing
February 2012

Erythropoiesis versus inflammation in Hereditary Spherocytosis clinical outcome.

Clin Biochem 2011 Sep 17;44(13):1137-1143. Epub 2011 Jun 17.

Faculdade de Farmácia, Universidade do Porto, Rua Aníbal Cunha, 164, 4050-047, Porto, Portugal; Instituto de Biologia Molecular e Celular (IBMC), Universidade do Porto, Rua do Campo Alegre, 823, 4150-180, Porto, Portugal. Electronic address:

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http://dx.doi.org/10.1016/j.clinbiochem.2011.06.006DOI Listing
September 2011

Complementary markers for the clinical severity classification of hereditary spherocytosis in unsplenectomized patients.

Blood Cells Mol Dis 2011 Feb 8;46(2):166-70. Epub 2010 Dec 8.

Serviço de Bioquímica, Faculdade de Farmácia, Universidade do Porto, Porto, Portugal.

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http://dx.doi.org/10.1016/j.bcmd.2010.11.001DOI Listing
February 2011

Erythrocyte membrane protein destabilization versus clinical outcome in 160 Portuguese Hereditary Spherocytosis patients.

Br J Haematol 2010 Jun 21;149(5):785-94. Epub 2010 Mar 21.

Serviço de Bioquímica, Faculdade de Farmácia da Universidade do Porto, Rua Aníbal Cunha, Porto, Portugal.

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http://doi.wiley.com/10.1111/j.1365-2141.2010.08166.x
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http://dx.doi.org/10.1111/j.1365-2141.2010.08166.xDOI Listing
June 2010

Erythropoietin promotes deleterious cardiovascular effects and mortality risk in a rat model of chronic sports doping.

Cardiovasc Toxicol 2009 Dec;9(4):201-10

Institute of Pharmacology & Experimental Therapeutics, IBILI, Medicine Faculty, Sub-Unit 1 (Polo III), Coimbra University, 3004-504, Coimbra, Portugal.

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http://dx.doi.org/10.1007/s12012-009-9054-2DOI Listing
December 2009

Gene symbol: UGT1A1. Disease: Crigler-Najjar syndrome 1.

Hum Genet 2008 Oct;124(3):301

Instituto Politécnico de Bragança, Escola Superior de Saúde, Dr. António Bernardino de Almeida, NA, 4200-072 Porto, Bragança, Portugal.

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October 2008

[Platelet indices in chronic alcoholic liver disease patients with thrombocytopenia].

Arq Gastroenterol 2007 Jul-Sep;44(3):201-4

Departamento de Tecnologias de Diagnóstico e Terapêutica, Escola Superior de Saúde, Instituto Politécnico de Bragança, Portugal.

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August 2008

[Etiology of urinary tract infections and antimicrobial susceptibility of urinary pathogens].

Acta Med Port 2007 Nov-Dec;20(6):543-50. Epub 2008 Feb 13.

Departamento de Diagnóstico e Terapêutica, Escola Superior de Saúde, Escola Superior Agrária, Instituto Politécnico de Bragança, Bragança.

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June 2008

Hematologically important mutations: Shwachman-Diamond syndrome.

Blood Cells Mol Dis 2008 Mar-Apr;40(2):183-4. Epub 2007 Oct 4.

Escola Superior de Saúde, Instituto Politécnico de Bragança, Avenida D. Afonso V, 5300-121 Bragança, Portugal.

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http://dx.doi.org/10.1016/j.bcmd.2007.07.008DOI Listing
May 2008

Identification of a novel AluSx-mediated deletion of exon 3 in the SBDS gene in a patient with Shwachman-Diamond syndrome.

Blood Cells Mol Dis 2007 Jul-Aug;39(1):96-101. Epub 2007 Mar 21.

Escola Superior de Saúde, Instituto Politécnico de Bragança, Bragança, Portugal.

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http://dx.doi.org/10.1016/j.bcmd.2007.02.002DOI Listing
September 2007

Analysis of the UDP-glucuronosyltransferase gene in Portuguese patients with a clinical diagnosis of Gilbert and Crigler-Najjar syndromes.

Blood Cells Mol Dis 2006 Jan-Feb;36(1):91-7. Epub 2005 Nov 2.

Escola Superior de Saúde, Instituto Politécnico de Bragança, Avenida D. Afonso V, 5300-121 Bragança, Portugal.

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http://dx.doi.org/10.1016/j.bcmd.2005.09.002DOI Listing
May 2006

Hematologically important mutations: bilirubin UDP-glucuronosyltransferase gene mutations in Gilbert and Crigler-Najjar syndromes.

Authors:
Elísio Costa

Blood Cells Mol Dis 2006 Jan-Feb;36(1):77-80. Epub 2005 Dec 28.

Escola Superior de Saúde do Instituto Politécnico de Bragança, Avenida D. Afonso V, 5300-121 Bragança, Portugal.

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http://dx.doi.org/10.1016/j.bcmd.2005.10.006DOI Listing
May 2006

Molecular characterization of a Portuguese patient with Shwachman-Diamond syndrome.

J Pediatr Gastroenterol Nutr 2005 Jul;41(1):115-6

Serviço de Pediatria, Hospital Central Especializado de Crianças Maria Pia, Porto, Portugal.

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http://dx.doi.org/10.1097/01.mpg.0000155184.61625.fcDOI Listing
July 2005

A new case of (TA)8 allele in the UGT1A1 gene promoter in a Caucasian girl with Gilbert syndrome.

Pediatr Hematol Oncol 2004 Jul-Aug;21(5):371-4

Serviço de Hematologia, Hospital de Crianças Maria Pia, Porto, Portugal.

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http://www.tandfonline.com/doi/full/10.1080/0888001049045703
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http://dx.doi.org/10.1080/08880010490457033DOI Listing
January 2005

[Glucose-6-phosphate dehydrogenase deficiency, neonatal hyperbilirubinemia and Gilbert syndrome].

Acta Med Port 2002 Nov-Dec;15(6):409-12

Serviço de Hematologia, Hospital Maria Pia, Serviços de Hematologia Clínica e Pediátrica, Hospital Geral de Santo António, Unidade de Genética Molecular, Instituto de Genética Doutor Jacinto de Magalhães, Porto.

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May 2003