Elisabet Svenungsson

Elisabet Svenungsson

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Elisabet Svenungsson

Elisabet Svenungsson

Publications by authors named "Elisabet Svenungsson"

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Do DMARDs and biologic agents protect from cardiovascular disease in patients with inflammatory arthropathies?

Autoimmun Rev 2019 Dec 23;18(12):102401. Epub 2019 Oct 23.

Amsterdam Rheumatology immunology Center, Amsterdam University Medical Center- Location VUmc* & Reade Rheumatology**, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1016/j.autrev.2019.102401DOI Listing
December 2019

Sjögren's syndrome in Systemic Lupus Erythematosus - a subset characterized by a systemic inflammatory state.

J Rheumatol 2019 Sep 15. Epub 2019 Sep 15.

The Swedish Research Council (grant no: 2014-33867), Swedish Heart- Lung Foundation (grants no: 20130430, 20130552,20170257), Stockholm County Council (ALF, grants no: 2014016, 20170038), The King Gustaf V 80th Birthday Fund (grant no FAI- 2017-0390), The Swedish Rheumatism Association (grants no: R-739631), Karolinska Institutet´s Foundations, The Swedish Society of Medicine, Ingegerd Johansson´s foundation (SLS-713911). The Swedish Dental Society, Clinical Research grants from Sörmland's county (no: DLL-614351, DLL-648991), Susanna Eketjäll is an employee at AstraZeneca, and Astra Zeneca provided reagents for the cytokine analyses, but AstraZeneca had no impact on the analyses or on of the presentations in this manuscript. Address correspondence to Elisabet Svenungsson Department of Medicine Solna, Unit of Rheumatology D2:01 Karolinska Institutet SE-171 76 Stockholm, Sweden Email:

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http://dx.doi.org/10.3899/jrheum.190250DOI Listing
September 2019

Microparticles in the blood of patients with SLE: Size, content of mitochondria and role in circulating immune complexes.

J Autoimmun 2019 Aug 16;102:142-149. Epub 2019 May 16.

Unit of Rheumatology, Department of Medicine, Solna, Karolinska Institutet, Karolinska University Hospital, SE-171 76, Stockholm, Sweden.

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http://dx.doi.org/10.1016/j.jaut.2019.05.003DOI Listing
August 2019

High levels of circulating interferons type I, type II and type III associate with distinct clinical features of active systemic lupus erythematosus.

Arthritis Res Ther 2019 Apr 29;21(1):107. Epub 2019 Apr 29.

Rheumatology Unit, Department of Medicine, Karolinska Institutet, Karolinska University Hospital, SE-171 76, Stockholm, Sweden.

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http://dx.doi.org/10.1186/s13075-019-1878-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6489203PMC
April 2019

Cytokine Profiles in Autoantibody Defined Subgroups of Systemic Lupus Erythematosus.

J Proteome Res 2019 Mar 18;18(3):1208-1217. Epub 2019 Feb 18.

Computational Life Science Cluster (CLiC), Department of Chemistry , Umeå University , 901 87 Umeå , Sweden.

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http://dx.doi.org/10.1021/acs.jproteome.8b00811DOI Listing
March 2019

Antiphospholipid Antibodies in Patients With Myocardial Infarction.

Ann Intern Med 2019 02 23;170(4):277-280. Epub 2018 Oct 23.

Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden (G.G., N.S., B.K., K.A., U.D., K.E., L.R., E.S.).

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http://dx.doi.org/10.7326/M18-2130DOI Listing
February 2019

Mass spectrometry-based analysis of cerebrospinal fluid from arthritis patients-immune-related candidate proteins affected by TNF blocking treatment.

Arthritis Res Ther 2019 02 15;21(1):60. Epub 2019 Feb 15.

Rheumatology Unit, Department of Medicine, Solna, Center of Molecular Medicine (CMM), Karolinska Institutet, Karolinska University Hospital, SE-17176, Stockholm, Sweden.

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https://arthritis-research.biomedcentral.com/articles/10.118
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http://dx.doi.org/10.1186/s13075-019-1846-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6377734PMC
February 2019

Microparticles as autoantigens in systemic lupus erythematosus.

Eur J Clin Invest 2018 Dec 21;48(12):e13010. Epub 2018 Oct 21.

Department of Medicine, Duke University Medical Center, Durham, North Carolina.

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http://doi.wiley.com/10.1111/eci.13010
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http://dx.doi.org/10.1111/eci.13010DOI Listing
December 2018

Response to: 'Increased stroke incidence in systemic lupus erythematosus patients: risk factors or disease itself?' by Bruzzese and Zullo.

Ann Rheum Dis 2018 10 16;77(10):e72. Epub 2017 Nov 16.

Department of Medicine Solna, Clinical Epidemiology Unit, Karolinska Institutet, Stockholm, Sweden.

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http://dx.doi.org/10.1136/annrheumdis-2017-212604DOI Listing
October 2018

Obstetric antiphospholipid syndrome.

Lupus Sci Med 2018 25;5(1):e000197. Epub 2018 Sep 25.

Unit of Rheumatology, Department of Medicine, Solna, Karolinska Institutet and Karolinska University Hospital, Stockholm, Sweden.

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http://dx.doi.org/10.1136/lupus-2016-000197DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6195166PMC
September 2018

Dr. Rossides, reply.

J Rheumatol 2018 07;45(7):1070

Karolinska Institutet, Clinical Epidemiology Division, Department of Medicine Solna, Stockholm, Sweden.

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http://dx.doi.org/10.3899/jrheum.180122DOI Listing
July 2018

TNF-α and plasma albumin as biomarkers of disease activity in systemic lupus erythematosus.

Lupus Sci Med 2018 4;5(1):e000260. Epub 2018 Jun 4.

Rheumatology Unit, Department of Medicine Solna, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden.

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http://dx.doi.org/10.1136/lupus-2018-000260DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6018889PMC
June 2018

Kynurenine pathway is altered in patients with SLE and associated with severe fatigue.

Lupus Sci Med 2018 23;5(1):e000254. Epub 2018 May 23.

Rheumatology Unit, Department of Medicine, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden.

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http://dx.doi.org/10.1136/lupus-2017-000254DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5976103PMC
May 2018

Autoimmune reactivity to malondialdehyde adducts in systemic lupus erythematosus is associated with disease activity and nephritis.

Arthritis Res Ther 2018 02 26;20(1):36. Epub 2018 Feb 26.

Department of Medicine, Rheumatology Unit, Karolinska Institutet and Karolinska University Hospital, Center for Molecular Medicine, Stockholm, Sweden.

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http://dx.doi.org/10.1186/s13075-018-1530-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5827973PMC
February 2018

Mortality and Functionality after Stroke in Patients with Systemic Lupus Erythematosus.

J Rheumatol 2017 Nov 15;44(11):1590-1596. Epub 2017 Sep 15.

From the Clinical Epidemiology Unit, Department of Medicine Solna, and the Unit of Rheumatology, Solna, and Stroke Research Network, Södersjukhuset, and Department of Clinical Science and Education, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden; Division of Epidemiology, Department of Health Research and Policy, and Division of Immunology and Rheumatology, Department of Medicine, Stanford School of Medicine, Stanford University, Stanford, California, USA.

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http://dx.doi.org/10.3899/jrheum.170241DOI Listing
November 2017

Thrombin activatable fibrinolysis inhibitor (TAFI) - A possible link between coagulation and complement activation in the antiphospholipid syndrome (APS).

Thromb Res 2017 Oct 24;158:168-173. Epub 2017 Jun 24.

Unit of Rheumatology, Department of Medicine, Solna, Karolinska Institutet, Karolinska University Hospital, SE-171 76 Stockholm, Sweden.

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http://dx.doi.org/10.1016/j.thromres.2017.06.028DOI Listing
October 2017

Depressed serum IgM levels in SLE are restricted to defined subgroups.

Clin Immunol 2017 10 15;183:304-315. Epub 2017 Sep 15.

Department of Medicine, Rheumatology Unit, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden.

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http://dx.doi.org/10.1016/j.clim.2017.09.013DOI Listing
October 2017

Stroke in systemic lupus erythematosus: a Swedish population-based cohort study.

Ann Rheum Dis 2017 Sep 11;76(9):1544-1549. Epub 2017 Apr 11.

Department of Medicine Solna, Clinical Epidemiology Unit, Karolinska Institutet, Stockholm, Sweden.

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http://dx.doi.org/10.1136/annrheumdis-2016-210973DOI Listing
September 2017

A single nucleotide polymorphism in the gene leading to reduced oxidative burst is associated with systemic lupus erythematosus.

Ann Rheum Dis 2017 Sep 12;76(9):1607-1613. Epub 2017 Jun 12.

Division of Medical Inflammation Research, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden.

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http://dx.doi.org/10.1136/annrheumdis-2017-211287DOI Listing
September 2017

Multivariate strategy for the sample selection and integration of multi-batch data in metabolomics.

Metabolomics 2017 24;13(10):114. Epub 2017 Aug 24.

Computational Life Science Cluster (CLiC), Department of Chemistry, Umeå University, 901 81 Umeå, Sweden.

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http://dx.doi.org/10.1007/s11306-017-1248-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5570768PMC
August 2017

Antiphospholipid Antibodies in Lupus Nephritis.

PLoS One 2016 23;11(6):e0158076. Epub 2016 Jun 23.

Department of Medicine, Rheumatology Unit, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0158076PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4919007PMC
July 2017

Transancestral mapping and genetic load in systemic lupus erythematosus.

Authors:
Carl D Langefeld Hannah C Ainsworth Deborah S Cunninghame Graham Jennifer A Kelly Mary E Comeau Miranda C Marion Timothy D Howard Paula S Ramos Jennifer A Croker David L Morris Johanna K Sandling Jonas Carlsson Almlöf Eduardo M Acevedo-Vásquez Graciela S Alarcón Alejandra M Babini Vicente Baca Anders A Bengtsson Guillermo A Berbotto Marc Bijl Elizabeth E Brown Hermine I Brunner Mario H Cardiel Luis Catoggio Ricard Cervera Jorge M Cucho-Venegas Solbritt Rantapää Dahlqvist Sandra D'Alfonso Berta Martins Da Silva Iñigo de la Rúa Figueroa Andrea Doria Jeffrey C Edberg Emőke Endreffy Jorge A Esquivel-Valerio Paul R Fortin Barry I Freedman Johan Frostegård Mercedes A García Ignacio García de la Torre Gary S Gilkeson Dafna D Gladman Iva Gunnarsson Joel M Guthridge Jennifer L Huggins Judith A James Cees G M Kallenberg Diane L Kamen David R Karp Kenneth M Kaufman Leah C Kottyan László Kovács Helle Laustrup Bernard R Lauwerys Quan-Zhen Li Marco A Maradiaga-Ceceña Javier Martín Joseph M McCune David R McWilliams Joan T Merrill Pedro Miranda José F Moctezuma Swapan K Nath Timothy B Niewold Lorena Orozco Norberto Ortego-Centeno Michelle Petri Christian A Pineau Bernardo A Pons-Estel Janet Pope Prithvi Raj Rosalind Ramsey-Goldman John D Reveille Laurie P Russell José M Sabio Carlos A Aguilar-Salinas Hugo R Scherbarth Raffaella Scorza Michael F Seldin Christopher Sjöwall Elisabet Svenungsson Susan D Thompson Sergio M A Toloza Lennart Truedsson Teresa Tusié-Luna Carlos Vasconcelos Luis M Vilá Daniel J Wallace Michael H Weisman Joan E Wither Tushar Bhangale Jorge R Oksenberg John D Rioux Peter K Gregersen Ann-Christine Syvänen Lars Rönnblom Lindsey A Criswell Chaim O Jacob Kathy L Sivils Betty P Tsao Laura E Schanberg Timothy W Behrens Earl D Silverman Marta E Alarcón-Riquelme Robert P Kimberly John B Harley Edward K Wakeland Robert R Graham Patrick M Gaffney Timothy J Vyse

Nat Commun 2017 07 17;8:16021. Epub 2017 Jul 17.

Divisions of Genetics and Molecular Medicine and Immunology, Infection and Inflammatory Diseases, King's College London, Guy's Hospital, London SE1 9RT, UK.

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http://dx.doi.org/10.1038/ncomms16021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5520018PMC
July 2017

Effect of Corticosteroids and Cyclophosphamide on Sex Hormone Profiles in Male Patients With Systemic Lupus Erythematosus or Systemic Sclerosis.

Arthritis Rheumatol 2017 06 4;69(6):1272-1279. Epub 2017 May 4.

Karolinska University Hospital, Karolinska Institutet, Stockholm, Sweden.

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http://dx.doi.org/10.1002/art.40057DOI Listing
June 2017

IFN-λ1 with Th17 axis cytokines and IFN-α define different subsets in systemic lupus erythematosus (SLE).

Arthritis Res Ther 2017 06 15;19(1):139. Epub 2017 Jun 15.

Rheumatology Unit, Department of Medicine, Karolinska Institutet, Karolinska University Hospital, SE-171 76, Stockholm, Sweden.

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http://dx.doi.org/10.1186/s13075-017-1344-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5471711PMC
June 2017

Early-onset Preeclampsia in Lupus Pregnancy.

Paediatr Perinat Epidemiol 2017 01 12;31(1):29-36. Epub 2016 Dec 12.

Division of Rheumatology, Hospital for Special Surgery, Weill Cornell Medical College, New York, NY.

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http://dx.doi.org/10.1111/ppe.12332DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5624307PMC
January 2017

Interferon (IFN)-λ is a potential mediator in lupus nephritis.

Lupus Sci Med 2016 22;3(1):e000170. Epub 2016 Nov 22.

Department of Medicine, Unit of Rheumatology , Karolinska University Hospital, Karolinska Institute , Stockholm , Sweden.

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http://dx.doi.org/10.1136/lupus-2016-000170DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5133405PMC
November 2016

Microparticles in the blood of patients with systemic lupus erythematosus (SLE): phenotypic characterization and clinical associations.

Sci Rep 2016 10 25;6:36025. Epub 2016 Oct 25.

Unit of Rheumatology, Department of Medicine, Solna, Karolinska Institutet, Karolinska University Hospital, SE-171 76 Stockholm, Sweden.

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http://dx.doi.org/10.1038/srep36025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5078765PMC
October 2016

Ofatumumab treatment in lupus nephritis patients.

Clin Kidney J 2016 Aug 5;9(4):552-5. Epub 2016 Jun 5.

Department of Medicine, Rheumatology Unit , Karolinska Institute , Stockholm , Sweden.

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http://dx.doi.org/10.1093/ckj/sfw022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4957712PMC
August 2016

Periodontitis Increases the Risk of a First Myocardial Infarction: A Report From the PAROKRANK Study.

Circulation 2016 Feb 13;133(6):576-83. Epub 2016 Jan 13.

From Departments of Medicine K2 (L.R., U.d.F., B.K., A.N., E.S.), Dental Medicine (K.B., E.E., A.G., J.H., N.R., B.K.), and Division of Cardiovascular Epidemiology IMM (U.d.F.), Karolinska Institutet, Stockholm, Sweden; Department Medical Sciences, Uppsala University, Sweden (B.L.); Department of Clinical Sciences Danderyd, Karolinska Institutet, Stockholm, Sweden (Å.N.); Center for Safety Research, KTH Royal Institute of Technology, Stockholm, Sweden (P.N.); and Faculty of Odontology, Department of Periodontology, Malmö University, Sweden (B.K.).

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http://circ.ahajournals.org/content/early/2016/01/13/CIRCULA
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http://circ.ahajournals.org/lookup/doi/10.1161/CIRCULATIONAH
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http://dx.doi.org/10.1161/CIRCULATIONAHA.115.020324DOI Listing
February 2016

Case definitions in Swedish register data to identify systemic lupus erythematosus.

BMJ Open 2016 Jan 4;6(1):e007769. Epub 2016 Jan 4.

Clinical Epidemiology Unit, Department of Medicine, Solna Karolinska Institute, Stockholm, Sweden Division of Epidemiology, Department of Health Research and Policy, Stanford School of Medicine, Stanford, California, USA Division of Immunology and Rheumatology, Department of Medicine, Stanford School of Medicine, Stanford, California, USA.

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http://dx.doi.org/10.1136/bmjopen-2015-007769DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4716148PMC
January 2016

Cigarette smoking, antiphospholipid antibodies and vascular events in Systemic Lupus Erythematosus.

Ann Rheum Dis 2015 Aug 1;74(8):1537-43. Epub 2014 Apr 1.

Rheumatology Unit, Department of Medicine, Karolinska University Hospital, Solna, Karolinska Institutet, Stockholm, Sweden.

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http://dx.doi.org/10.1136/annrheumdis-2013-205159DOI Listing
August 2015

Systemic lupus erythematosus prevalence in Sweden in 2010: what do national registers say?

Arthritis Care Res (Hoboken) 2014 Nov;66(11):1710-7

Karolinska Institutet, Stockholm, Sweden; Stanford School of Medicine, Stanford, California.

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http://dx.doi.org/10.1002/acr.22355DOI Listing
November 2014

Studies of fibrin formation and fibrinolytic function in patients with the antiphospholipid syndrome.

Thromb Res 2014 May 28;133(5):936-44. Epub 2014 Feb 28.

Karolinska Institutet, Department of Medicine Solna, Unit of Rheumatology, Karolinska University Hospital, Stockholm, Sweden; Karolinska Institutet, Department of Clinical Sciences, Danderyds Hospital, Division of Cardiovascular Medicine, Stockholm, Sweden.

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https://linkinghub.elsevier.com/retrieve/pii/S00493848140010
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http://dx.doi.org/10.1016/j.thromres.2014.02.023DOI Listing
May 2014

Definitions of and contributions to cardiovascular disease in systemic lupus erythematosus.

Autoimmunity 2014 Mar 14;47(2):67-76. Epub 2013 Nov 14.

Rheumatology Unit, Department of Medicine, Karolinska Institutet, Karolinska University Hospital , Stockholm , Sweden.

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http://dx.doi.org/10.3109/08916934.2013.856005DOI Listing
March 2014

Risk factors for cardiovascular mortality in patients with systemic lupus erythematosus, a prospective cohort study.

Arthritis Res Ther 2012 ;14(2):R46

Rheumatology Unit, Department of Medicine, Karolinska University Hospital, Solna, Karolinska Institutet, SE-171 76 Stockholm, Sweden.

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http://dx.doi.org/10.1186/ar3759DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4060356PMC
May 2013

Women's experience of SLE-related fatigue: a focus group interview study.

Rheumatology (Oxford) 2010 Oct 23;49(10):1935-42. Epub 2010 Jun 23.

Department of Neurobiology, Care Sciences and Society (NVS), Division of Nursing, Karolinska Institutet, Stockholm, Sweden.

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http://dx.doi.org/10.1093/rheumatology/keq174DOI Listing
October 2010

Copy number, linkage disequilibrium and disease association in the FCGR locus.

Hum Mol Genet 2010 Aug 27;19(16):3282-94. Epub 2010 May 27.

Department of Medicine, Cambridge Institute for Medical Research, University of Cambridge School of Clinical Medicine, Addenbrooke's Hospital, Hills Road, Cambridge CB2 0XY, UK.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2908468PMC
http://dx.doi.org/10.1093/hmg/ddq216DOI Listing
August 2010

Decreased levels of soluble amyloid beta-protein precursor and beta-amyloid protein in cerebrospinal fluid of patients with systemic lupus erythematosus.

Arthritis Res Ther 2004 22;6(2):R129-36. Epub 2004 Jan 22.

Department of Rheumatology and Inflammation Research, Göteborg University, Sahlgrenska University Hospital, Göteborg, Sweden.

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http://dx.doi.org/10.1186/ar1040DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC400431PMC
October 2005

Decreased binding of annexin v to endothelial cells: a potential mechanism in atherothrombosis of patients with systemic lupus erythematosus.

Arterioscler Thromb Vasc Biol 2005 Jan 11;25(1):198-203. Epub 2004 Nov 11.

Department of Medicine, Center for Infectious Medicine, Karolinska University Hospital, Huddinge, 141 86 Stockholm, Sweden.

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https://www.ahajournals.org/doi/10.1161/01.ATV.0000150415.18
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http://dx.doi.org/10.1161/01.ATV.0000150415.18759.36DOI Listing
January 2005

Lipid peroxidation is enhanced in patients with systemic lupus erythematosus and is associated with arterial and renal disease manifestations.

Arthritis Rheum 2005 Jan;52(1):192-200

Center for Infectious Medicine and Center for Metabolism and Endocrinology, Department of Medicine, Karolinska University Hospital, Huddinge, S-141 86 Stockholm, Sweden.

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http://dx.doi.org/10.1002/art.20780DOI Listing
January 2005

The A-1087IL-10 allele is associated with cardiovascular disease in SLE.

Atherosclerosis 2004 Dec;177(2):409-14

Rheumatology Unit, Department of Medicine at Karolinska University Hospital Solna, Karolinska Institutet, Stockholm, Sweden.

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http://linkinghub.elsevier.com/retrieve/pii/S002191500400398
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http://dx.doi.org/10.1016/j.atherosclerosis.2004.07.026DOI Listing
December 2004