Elisa Giovannetti

TGF-β induces miR-100 and miR-125b but blocks let-7a through LIN28B controlling PDAC progression.

• Authors:
• Silvia Ottaviani,
• Justin Stebbing,
• Adam E Frampton,
• Sladjana Zagorac,
• Jonathan Krell,
• Alexander de Giorgio,
• Sara M Trabulo,
• Van T M Nguyen,
• Luca Magnani,
• Hugang Feng,
• Elisa Giovannetti,
• Niccola Funel,
• Thomas M Gress,
• Long R Jiao,
• Ylenia Lombardo,
• Nicholas R Lemoine,
• Christopher Heeschen,
• Leandro Castellano

• May 2018

Aminopeptidase antibodies in mesothelioma: new wine deserves new sacks.

• Authors:
• Jan P van Meerbeeck,
• Gerrit Jansen,
• Elisa Giovannetti,
• Godefridus J Peters

• May 2018

Glypican-1 is enriched in circulating-exosomes in pancreatic cancer and correlates with tumor burden.

• Authors:
• Adam E Frampton,
• Mireia Mato Prado,
• Elena López-Jiménez,
• Ana Belen Fajardo-Puerta,
• Zaynab A R Jawad,
• Phillip Lawton,
• Elisa Giovannetti,
• Nagy A Habib,
• Leandro Castellano,
• Justin Stebbing,
• Jonathan Krell,
• Long R Jiao

• April 2018

5'-nucleotidase cN-II emerges as a new predictive biomarker of response to gemcitabine/platinum combination chemotherapy in non-small cell lung cancer.

• Authors:
• Francesca Toffalorio,
• Mariacarmela Santarpia,
• Davide Radice,
• Christopher Adrian Jaramillo,
• Gianluca Spitaleri,
• Michela Manzotti,
• Chiara Catania,
• Lars Petter Jordheim,
• Giuseppe Pelosi,
• Godefridus J Peters,
• Carmelo Tibaldi,
• Niccola Funel,
• Lorenzo Spaggiari,
• Filippo de Braud,
• Tommaso De Pas,
• Elisa Giovannetti

• March 2018

Double Trouble: A Case Series on Concomitant Genetic Aberrations in NSCLC.

• Authors:
• Nele Van Der Steen,
• Yves Mentens,
• Marc Ramael,
• Leticia G Leon,
• Paul Germonpré,
• Jose Ferri,
• David R Gandara,
• Elisa Giovannetti,
• Godefridus J Peters,
• Patrick Pauwels,
• Christian Rolfo

• January 2018

A synthetic lethal bullet.

• Authors:
• Christian Rolfo,
• Elisa Giovannetti

• January 2018

Erratum to: miRNAs: micro-managers of anticancer combination therapies.

• Authors:
• Judy R van Beijnum,
• Elisa Giovannetti,
• Dennis Poel,
• Patrycja Nowak-Sliwinska,
• Arjan W Griffioen

• November 2017

Profiling of different pancreatic cancer cells used as models for metastatic behaviour shows large variation in their N-glycosylation.

• Authors:
• Stephanie Holst,
• Ana I Belo,
• Elisa Giovannetti,
• Irma van Die,
• Manfred Wuhrer

• November 2017

miRNA profiling for diagnosis, prognosis and stratification of cancer treatment in cholangiocarcinoma.

• Authors:
• Jisce R Puik,
• Laura L Meijer,
• Tessa Ys Le Large,
• Mireia Mato Prado,
• Adam E Frampton,
• Geert Kazemier,
• Elisa Giovannetti

• September 2017

Swarm Intelligence-Enhanced Detection of Non-Small-Cell Lung Cancer Using Tumor-Educated Platelets.

• Authors:
• Myron G Best,
• Nik Sol,
• Sjors G J G In 't Veld,
• Adrienne Vancura,
• Mirte Muller,
• Anna-Larissa N Niemeijer,
• Aniko V Fejes,
• Lee-Ann Tjon Kon Fat,
• Anna E Huis In 't Veld,
• Cyra Leurs,
• Tessa Y Le Large,
• Laura L Meijer,
• Irsan E Kooi,
• François Rustenburg,
• Pepijn Schellen,
• Heleen Verschueren,
• Edward Post,
• Laurine E Wedekind,
• Jillian Bracht,
• Michelle Esenkbrink,
• Leon Wils,
• Francesca Favaro,
• Jilian D Schoonhoven,
• Jihane Tannous,
• Hanne Meijers-Heijboer,
• Geert Kazemier,
• Elisa Giovannetti,
• Jaap C Reijneveld,
• Sander Idema,
• Joep Killestein,
• Michal Heger,
• Saskia C de Jager,
• Rolf T Urbanus,
• Imo E Hoefer,
• Gerard Pasterkamp,
• Christine Mannhalter,
• Jose Gomez-Arroyo,
• Harm-Jan Bogaard,
• David P Noske,
• W Peter Vandertop,
• Daan van den Broek,
• Bauke Ylstra,
• R Jonas A Nilsson,
• Pieter Wesseling,
• Niki Karachaliou,
• Rafael Rosell,
• Elizabeth Lee-Lewandrowski,
• Kent B Lewandrowski,
• Bakhos A Tannous,
• Adrianus J de Langen,
• Egbert F Smit,
• Michel M van den Heuvel,
• Thomas Wurdinger

• August 2017

Enhanced efficacy of AKT and FAK kinase combined inhibition in squamous cell lung carcinomas with stable reduction in PTEN.

• Authors:
• Andrea Cavazzoni,
• Silvia La Monica,
• Roberta Alfieri,
• Andrea Ravelli,
• Nele Van Der Steen,
• Rocco Sciarrillo,
• Denise Madeddu,
• Costanza Anna Maria Lagrasta,
• Federico Quaini,
• Mara Bonelli,
• Claudia Fumarola,
• Daniele Cretella,
• Graziana Digiacomo,
• Marcello Tiseo,
• Godefridus J Peters,
• Andrea Ardizzoni,
• Pier Giorgio Petronini,
• Elisa Giovannetti

• August 2017

Resistance Mechanisms to AZD9291 and Rociletinib-Letter.

• Authors:
• Nele Van Der Steen,
• Christian Rolfo,
• Patrick Pauwels,
• Adrianus J de Langen,
• Godefridus J Peters,
• Elisa Giovannetti

• July 2017

Drug resistance in pancreatic cancer: Impact of altered energy metabolism.

• Authors:
• Cristoforo Grasso,
• Gerrit Jansen,
• Elisa Giovannetti

• June 2017

miRNAs: micro-managers of anticancer combination therapies.

• Authors:
• Judy R van Beijnum,
• Elisa Giovannetti,
• Dennis Poel,
• Patrycja Nowak-Sliwinska,
• Arjan W Griffioen

• May 2017

Development of bioluminescent chick chorioallantoic membrane (CAM) models for primary pancreatic cancer cells: a platform for drug testing.

• Authors:
• Maria Rovithi,
• Amir Avan,
• Niccola Funel,
• Leticia G Leon,
• Valentina E Gomez,
• Thomas Wurdinger,
• Arjan W Griffioen,
• Henk M W Verheul,
• Elisa Giovannetti

• March 2017

Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors and Chemotherapy: A Glimmer of Hope?

• Authors:
• Nele Van Der Steen,
• Christian Diego Rolfo,
• Patrick Pauwels,
• Godefridus J Peters,
• Elisa Giovannetti

• February 2017

A specific inhibitor of lactate dehydrogenase overcame the resistance toward gemcitabine in hypoxic mesothelioma cells, and modulated the expression of the human equilibrative transporter-1.

• Authors:
• Elisa Giovannetti,
• Leticia G Leon,
• Valentina E Gómez,
• Paolo A Zucali,
• Filippo Minutolo,
• Godefridus J Peters

• December 2016

Better to be alone than in bad company: The antagonistic effect of cisplatin and crizotinib combination therapy in non-small cell lung cancer.

• Authors:
• Nele Van Der Steen,
• Christophe Deben,
• Vanessa Deschoolmeester,
• An Wouters,
• Filip Lardon,
• Christian Rolfo,
• Paul Germonpré,
• Elisa Giovannetti,
• Godefridus J Peters,
• Patrick Pauwels

• December 2016

P2.09: cMET in NSCLC: Expression, Amplification and Mutations: Track: Biology and Pathogenesis.

• Authors:
• Nele Van Der Steen,
• Christian Rolfo,
• Elisa Giovannetti,
• Pablo Reclusa,
• Godefridus J Peters,
• Patrick Pauwels

• October 2016

Role of Akt signaling in resistance to DNA-targeted therapy.

• Authors:
• Abolfazl Avan,
• Ravi Narayan,
• Elisa Giovannetti,
• Godefridus J Peters

• October 2016

FOLFIRINOX and translational studies: Towards personalized therapy in pancreatic cancer.

• Authors:
• Chiara Caparello,
• Laura L Meijer,
• Ingrid Garajova,
• Alfredo Falcone,
• Tessa Y Le Large,
• Niccola Funel,
• Geert Kazemier,
• Godefridus J Peters,
• Enrico Vasile,
• Elisa Giovannetti

• August 2016

Pharmacokinetics and pharmacogenetics of Gemcitabine as a mainstay in adult and pediatric oncology: an EORTC-PAMM perspective.

• Authors:
• Joseph Ciccolini,
• Cindy Serdjebi,
• Godefridus J Peters,
• Elisa Giovannetti

• July 2016

Prospective validation of microRNA signatures for detecting pancreatic malignant transformation in endoscopic-ultrasound guided fine-needle aspiration biopsies.

• Authors:
• Adam E Frampton,
• Jonathan Krell,
• Mireia Mato Prado,
• Tamara M H Gall,
• Nima Abbassi-Ghadi,
• Giovanna Del Vecchio Blanco,
• Niccola Funel,
• Elisa Giovannetti,
• Leandro Castellano,
• Mohamed Basyouny,
• Nagy A Habib,
• Harry Kaltsidis,
• Panagiotis Vlavianos,
• Justin Stebbing,
• Long R Jiao

• May 2016

Multifactorial resistance to aminopeptidase inhibitor prodrug CHR2863 in myeloid leukemia cells: down-regulation of carboxylesterase 1, drug sequestration in lipid droplets and pro-survival activation ERK/Akt/mTOR.

• Authors:
• Sue Ellen Verbrugge,
• Marjon Al,
• Yehuda G Assaraf,
• Sarah Kammerer,
• Durga M S H Chandrupatla,
• Richard Honeywell,
• Rene P J Musters,
• Elisa Giovannetti,
• Tom O'Toole,
• George L Scheffer,
• David Krige,
• Tanja D de Gruijl,
• Hans W M Niessen,
• Willem F Lems,
• Pieternella A Kramer,
• Rik J Scheper,
• Jacqueline Cloos,
• Gert J Ossenkoppele,
• Godefridus J Peters,
• Gerrit Jansen

• February 2016

Prognostic and Predictive Roles of Thymidylate Synthase Expression in Lung Cancer: The Debate Is Still Open.

• Authors:
• Elisa Giovannetti,
• Paolo A Zucali,
• Christian Rolfo,
• Yehuda G Assaraf,
• Godefridus J Peters

• February 2016

NF-κB drives acquired resistance to a novel mutant-selective EGFR inhibitor.

• Authors:
• Elena Galvani,
• Jing Sun,
• Leticia G Leon,
• Rocco Sciarrillo,
• Ravi S Narayan,
• Robert Tjin Tham Sjin,
• Kwangho Lee,
• Kadoaki Ohashi,
• Daniëlle A M Heideman,
• Roberta R Alfieri,
• Guus J Heynen,
• René Bernards,
• Egbert F Smit,
• William Pao,
• Godefridus J Peters,
• Elisa Giovannetti

• December 2015

Unraveling the complexity of autophagy: Potential therapeutic applications in Pancreatic Ductal Adenocarcinoma.

• Authors:
• Valentina E Gómez,
• Elisa Giovannetti,
• Godefridus J Peters

• December 2015

MicroRNA-21 links epithelial-to-mesenchymal transition and inflammatory signals to confer resistance to neoadjuvant trastuzumab and chemotherapy in HER2-positive breast cancer patients.

• Authors:
• Leticia De Mattos-Arruda,
• Giulia Bottai,
• Paolo G Nuciforo,
• Luca Di Tommaso,
• Elisa Giovannetti,
• Vicente Peg,
• Agnese Losurdo,
• José Pérez-Garcia,
• Giovanna Masci,
• Fabio Corsi,
• Javier Cortés,
• Joan Seoane,
• George A Calin,
• Libero Santarpia

• November 2015

Phase I Clinical Trial to Determine the Feasibility and Maximum Tolerated Dose of Panitumumab to Standard Gemcitabine-Based Chemoradiation in Locally Advanced Pancreatic Cancer.

• Authors:
• Annette A van Zweeden,
• Hans J van der Vliet,
• Johanna W Wilmink,
• Martijn R Meijerink,
• Otto W M Meijer,
• Anna M E Bruynzeel,
• Geertjan van Tienhoven,
• Elisa Giovannetti,
• Geert Kazemier,
• Maarten A J M Jacobs,
• Henk M W Verheul

• October 2015

Cytochrome P450 1B1 (CYP1B1) polymorphisms are associated with clinical outcome of docetaxel in non-small cell lung cancer (NSCLC) patients.

• Authors:
• Enrico Vasile,
• Carmelo Tibaldi,
• G Leticia Leon,
• Armida D'Incecco,
• Elisa Giovannetti

• July 2015

microRNAs with prognostic significance in pancreatic ductal adenocarcinoma: A meta-analysis.

• Authors:
• Adam E Frampton,
• Jonathan Krell,
• Nigel B Jamieson,
• Tamara M H Gall,
• Elisa Giovannetti,
• Niccola Funel,
• Mireia Mato Prado,
• Daniel Krell,
• Nagy A Habib,
• Leandro Castellano,
• Long R Jiao,
• Justin Stebbing

• July 2015

Usefulness of Measuring microRNAs in Bile and Plasma for Pancreatic Ductal Adenocarcinoma Diagnosis.

• Authors:
• Tessa Y S Le Large,
• Adam E Frampton,
• Laura L Meijer,
• Justin Stebbing,
• Geert Kazemier,
• Elisa Giovannetti

• May 2015

Platinum-induced neurotoxicity and preventive strategies: past, present, and future.

• Authors:
• Abolfazl Avan,
• Tjeerd J Postma,
• Cecilia Ceresa,
• Amir Avan,
• Guido Cavaletti,
• Elisa Giovannetti,
• Godefridus J Peters

• April 2015

Integrated molecular analysis to investigate the role of microRNAs in pancreatic tumour growth and progression.

• Authors:
• Adam E Frampton,
• Leandro Castellano,
• Teresa Colombo,
• Elisa Giovannetti,
• Jonathan Krell,
• Jimmy Jacob,
• Loredana Pellegrino,
• Laura Roca-Alonso,
• Niccola Funel,
• Tamara M H Gall,
• Raida Ahmad,
• Nagy A Habib,
• Thomas Knösel,
• Justin Stebbing,
• Long R Jiao

• February 2015

Genetic variation: effect on prostate cancer.

• Authors:
• Tristan M Sissung,
• Douglas K Price,
• Marzia Del Re,
• Ariel M Ley,
• Elisa Giovannetti,
• William D Figg,
• Romano Danesi

• December 2014

On the use of pharmacogenetics in cancer treatment and clinical trials.

• Authors:
• Jacques Robert,
• Valérie Le Morvan,
• Elisa Giovannetti,
• Godefridus J Peters,

• October 2014

Calcium/magnesium infusion for oxaliplatin-induced neuropathy: protective or not?

• Authors:
• Abolfazl Avan,
• Amir Avan,
• Elisa Giovannetti,
• Godefridus J Peters

• October 2014

Novel therapeutic strategies for patients with NSCLC that do not respond to treatment with EGFR inhibitors.

• Authors:
• Christian Rolfo,
• Elisa Giovannetti,
• David S Hong,
• T Bivona,
• Luis E Raez,
• Giuseppe Bronte,
• Lucio Buffoni,
• Noemí Reguart,
• Edgardo S Santos,
• Paul Germonpre,
• Mìquel Taron,
• Francesco Passiglia,
• Jan P Van Meerbeeck,
• Antonio Russo,
• Marc Peeters,
• Ignacio Gil-Bazo,
• Patrick Pauwels,
• Rafael Rosell

• September 2014

SNPs in PI3K-PTEN-mTOR and brain metastases in NSCLC--letter.

• Authors:
• Abolfazl Avan,
• Mina Maftouh,
• Amir Avan,
• Carmelo Tibaldi,
• Paolo A Zucali,
• Elisa Giovannetti

• July 2014

Galectin-4 expression is associated with reduced lymph node metastasis and modulation of Wnt/β-catenin signalling in pancreatic adenocarcinoma.

• Authors:
• Mina Maftouh,
• Ana I Belo,
• Amir Avan,
• Niccola Funel,
• Godefridus J Peters,
• Elisa Giovannetti,
• Irma Van Die

• July 2014

CYB5A and autophagy-mediated cell death in pancreatic cancer.

• Authors:
• Elisa Giovannetti,
• Giuseppe Giaccone

• April 2014

A microRNA meta-signature for pancreatic ductal adenocarcinoma.

• Authors:
• Adam E Frampton,
• Elisa Giovannetti,
• Nigel B Jamieson,
• Jonathan Krell,
• Tamara Mh Gall,
• Justin Stebbing,
• Long R Jiao,
• Leandro Castellano

• April 2014

A polymorphism in the promoter is associated with EZH2 expression but not with outcome in advanced pancreatic cancer patients.

• Authors:
• Mina Maftouh,
• Amir Avan,
• Niccola Funel,
• Elisa Paolicchi,
• Enrico Vasile,
• Paola Pacetti,
• Vanja Vaccaro,
• Pinuccia Faviana,
• Daniela Campani,
• Sara Caponi,
• Andrea Mambrini,
• Ugo Boggi,
• Maurizio Cantore,
• Michele Milella,
• Godefridus J Peters,
• Michele Reni,
• Elisa Giovannetti

• April 2014

Are erlotinib and gefitinib interchangeable, opposite or complementary for non-small cell lung cancer treatment? Biological, pharmacological and clinical aspects.

• Authors:
• Giuseppe Bronte,
• Christian Rolfo,
• Elisa Giovannetti,
• Giuseppe Cicero,
• Patrick Pauwels,
• Francesco Passiglia,
• Marta Castiglia,
• Sergio Rizzo,
• Francesca Lo Vullo,
• Eugenio Fiorentino,
• Jan Van Meerbeeck,
• Antonio Russo

• February 2014

MicroRNAs cooperatively inhibit a network of tumor suppressor genes to promote pancreatic tumor growth and progression.

• Authors:
• Adam E Frampton,
• Leandro Castellano,
• Teresa Colombo,
• Elisa Giovannetti,
• Jonathan Krell,
• Jimmy Jacob,
• Loredana Pellegrino,
• Laura Roca-Alonso,
• Niccola Funel,
• Tamara M H Gall,
• Alexander De Giorgio,
• Filipa G Pinho,
• Valerio Fulci,
• David J Britton,
• Raida Ahmad,
• Nagy A Habib,
• R Charles Coombes,
• Victoria Harding,
• Thomas Knösel,
• Justin Stebbing,
• Long R Jiao

• January 2014

Role of CYB5A in pancreatic cancer prognosis and autophagy modulation.

• Authors:
• Elisa Giovannetti,
• Qiuyan Wang,
• Amir Avan,
• Niccola Funel,
• Tonny Lagerweij,
• Jih-Hsiang Lee,
• Viola Caretti,
• Arjan van der Velde,
• Ugo Boggi,
• Yisong Wang,
• Enrico Vasile,
• Godefridus J Peters,
• Thomas Wurdinger,
• Giuseppe Giaccone

• January 2014

Predictive role of repair enzymes in the efficacy of Cisplatin combinations in pancreatic and lung cancer.

• Authors:
• Godefridus J Peters,
• Abolfazl Avan,
• Marielle Gallegos Ruiz,
• Vanessa Orsini,
• Amir Avan,
• Elisa Giovannetti,
• Egbert F Smit

• January 2014

Characterization of and protection from neurotoxicity induced by oxaliplatin, bortezomib and epothilone-B.

• Authors:
• Cecilia Ceresa,
• Abolfazl Avan,
• Elisa Giovannetti,
• Albert A Geldof,
• Amir Avan,
• Guido Cavaletti,
• Godefridus J Peters

• January 2014

Crizotinib inhibits metabolic inactivation of gemcitabine in c-Met-driven pancreatic carcinoma.

• Authors:
• Amir Avan,
• Viola Caretti,
• Niccola Funel,
• Elena Galvani,
• Mina Maftouh,
• Richard J Honeywell,
• Tonny Lagerweij,
• Olaf Van Tellingen,
• Daniela Campani,
• Dieter Fuchs,
• Henk M Verheul,
• Gerrit-Jan Schuurhuis,
• Ugo Boggi,
• Godefridus J Peters,
• Thomas Würdinger,
• Elisa Giovannetti

• November 2013

A single nucleotide polymorphism in EZH2 predicts overall survival rate in patients with cholangiocarcinoma.

• Authors:
• Elisa Paolicchi,
• Paola Pacetti,
• Elisa Giovannetti,
• Andrea Mambrini,
• Massimo Orlandi,
• Francesco Crea,
• Antonello A Romani,
• Roberta Tartarini,
• Romano Danesi,
• Godefridus J Peters,
• Maurizio Cantore

• November 2013

Serum miR-1290 as a marker of pancreatic cancer--letter.

• Authors:
• Adam E Frampton,
• Jonathan Krell,
• Geert Kazemier,
• Elisa Giovannetti

• September 2013

Prognostic factors in gemcitabine-cisplatin polychemotherapy regimens in pancreatic cancer: XPD-Lys751Gln polymorphism strikes back.

• Authors:
• Amir Avan,
• Paola Pacetti,
• Michele Reni,
• Michele Milella,
• Enrico Vasile,
• Andrea Mambrini,
• Vanja Vaccaro,
• Sara Caponi,
• Stefano Cereda,
• Godefridus J Peters,
• Maurizio Cantore,
• Elisa Giovannetti

• August 2013

"One marker does not fit all": additional translational and validation studies are needed to identify faithful predictors of pemetrexed activity in mesothelioma.

• Authors:
• Elisa Giovannetti,
• Godefridus J Peters,
• Paolo A Zucali

• August 2013

USP1 deubiquitinase: cellular functions, regulatory mechanisms and emerging potential as target in cancer therapy.

• Authors:
• Iraia García-Santisteban,
• Godefridus J Peters,
• Elisa Giovannetti,
• Jose Antonio Rodríguez

• August 2013

MAPK p38 and JNK have opposing activities on TRAIL-induced apoptosis activation in NSCLC H460 cells that involves RIP1 and caspase-8 and is mediated by Mcl-1.

• Authors:
• Kaamar Azijli,
• Saravanan Yuvaraj,
• Ingrid van Roosmalen,
• Koen Flach,
• Elisa Giovannetti,
• Godefridus J Peters,
• Steven de Jong,
• Frank A E Kruyt

• July 2013

An analysis of human equilibrative nucleoside transporter-1, ribonucleoside reductase subunit M1, ribonucleoside reductase subunit M2, and excision repair cross-complementing gene-1 expression in patients with resected pancreas adenocarcinoma: implications for adjuvant treatment.

• Authors:
• Amir Avan,
• Mina Maftouh,
• Elisa Giovannetti

• July 2013

Gender, cytidine deaminase, and 5-aza/decitabine--letter.

• Authors:
• Joseph Ciccolini,
• Godefridus J Peters,
• Elisa Giovannetti

• June 2013

Chemotherapy, targeted agents, antiemetics and growth-factors in human milk: how should we counsel cancer patients about breastfeeding?

• Authors:
• Barbara Pistilli,
• Giulia Bellettini,
• Elisa Giovannetti,
• Giovanni Codacci-Pisanelli,
• Hatem A Azim,
• Giovanni Benedetti,
• Maria Anna Sarno,
• Fedro A Peccatori

• May 2013

Distinct miRNA profiles are associated with malignant transformation of pancreatic cystic tumors revealing potential biomarkers for clinical use.

• Authors:
• Adam E Frampton,
• Tamara M H Gall,
• Elisa Giovannetti,
• Justin Stebbing,
• Leandro Castellano,
• Long R Jiao,
• Jonathan Krell

• May 2013

Molecular mechanisms underlying the antitumor activity of 3-aminopropanamide irreversible inhibitors of the epidermal growth factor receptor in non-small cell lung cancer.

• Authors:
• Elena Galvani,
• Elisa Giovannetti,
• Francesca Saccani,
• Andrea Cavazzoni,
• Leticia G Leon,
• Henk Dekker,
• Roberta Alfieri,
• Caterina Carmi,
• Marco Mor,
• Andrea Ardizzoni,
• Pier Giorgio Petronini,
• Godefridus J Peters

• January 2013

Role of miRNAs in the response to anticancer therapy.

• Authors:
• Adam E Frampton,
• Jonathan Krell,
• Elisa Giovannetti,
• Long R Jiao,
• Justin Stebbing

• November 2012

Defining a prognostic molecular profile for ductal adenocarcinoma of the pancreas highlights known key signaling pathways.

• Authors:
• Adam E Frampton,
• Jonathan Krell,
• Elisa Giovannetti,
• Daniel Krell,
• Justin Stebbing,
• Leandro Castellano,
• Long R Jiao

• October 2012

High-throughput microRNA (miRNAs) arrays unravel the prognostic role of MiR-211 in pancreatic cancer.

• Authors:
• Elisa Giovannetti,
• Arjan van der Velde,
• Niccola Funel,
• Enrico Vasile,
• Vittorio Perrone,
• Leticia G Leon,
• Nelide De Lio,
• Amir Avan,
• Sara Caponi,
• Luca E Pollina,
• Valentina Gallá,
• Hiroko Sudo,
• Alfredo Falcone,
• Daniela Campani,
• Ugo Boggi,
• Godefridus J Peters

Molecular mechanisms underlying the role of microRNAs in resistance to epidermal growth factor receptor-targeted agents and novel therapeutic strategies for treatment of non-small-cell lung cancer.

• Authors:
• Mina Maftouh,
• Amir Avan,
• Elena Galvani,
• Godefridus J Peters,
• Elisa Giovannetti

Pemetrexed induced thymidylate synthase inhibition in non-small cell lung cancer patients: a pilot study with 3'-deoxy-3'-[¹⁸F]fluorothymidine positron emission tomography.

• Authors:
• Virginie Frings,
• Astrid A M van der Veldt,
• Ronald Boellaard,
• Gerarda J M Herder,
• Elisa Giovannetti,
• Richard Honeywell,
• Godefridus J Peters,
• Erik Thunnissen,
• Otto S Hoekstra,
• Egbert F Smit

Pharmacogenetics of non-small cell lung cancer (NSCLC): time to "work it out"?

• Authors:
• Elena Galvani,
• Francesca Toffalorio,
• Godefridus J Peters,
• Tommaso De Pas,
• Elisa Giovannetti

Gefitinib inhibits invasive phenotype and epithelial-mesenchymal transition in drug-resistant NSCLC cells with MET amplification.

• Authors:
• Silvia La Monica,
• Cristina Caffarra,
• Francesca Saccani,
• Elena Galvani,
• Maricla Galetti,
• Claudia Fumarola,
• Mara Bonelli,
• Andrea Cavazzoni,
• Daniele Cretella,
• Rita Sirangelo,
• Rita Gatti,
• Marcello Tiseo,
• Andrea Ardizzoni,
• Elisa Giovannetti,
• Pier Giorgio Petronini,
• Roberta R Alfieri

Impact of microRNAs in resistance to chemotherapy and novel targeted agents in non-small cell lung cancer.

• Authors:
• Christian Rolfo,
• Daniele Fanale,
• David S Hong,
• Apostolia M Tsimberidou,
• Sarina A Piha-Paul,
• Patrick Pauwels,
• Jan P Van Meerbeeck,
• Stefano Caruso,
• Viviana Bazan,
• Giuseppe Cicero,
• Antonio Russo,
• Elisa Giovannetti

miR-211 modulates gemcitabine activity through downregulation of ribonucleotide reductase and inhibits the invasive behavior of pancreatic cancer cells.

• Authors:
• Mina Maftouh,
• Amir Avan,
• Niccola Funel,
• Adam E Frampton,
• Hamid Fiuji,
• Serena Pelliccioni,
• Leandro Castellano,
• Valentina Galla,
• Godefridus J Peters,
• Elisa Giovannetti

Selection of the best blood compartment to measure cytidine deaminase activity to stratify for optimal gemcitabine or cytarabine treatment.

• Authors:
• Godefridus J Peters,
• Richard J Honeywell,
• Marie Maulandi,
• Elisa Giovannetti,
• Nienke Losekoot,
• Marie-Christine Etienne-Grimaldi,
• Gerard Milano,
• Cindy Serdjebi,
• Joseph Ciccolini,

AKT1 and SELP polymorphisms predict the risk of developing cachexia in pancreatic cancer patients.

• Authors:
• Abolfazl Avan,
• Amir Avan,
• Tessa Y S Le Large,
• Andrea Mambrini,
• Niccola Funel,
• Mina Maftouh,
• Majid Ghayour-Mobarhan,
• Maurizio Cantore,
• Ugo Boggi,
• Godefridus J Peters,
• Paola Pacetti,
• Elisa Giovannetti

Molecular mechanisms underlying the role of microRNAs in the chemoresistance of pancreatic cancer.

• Authors:
• Ingrid Garajová,
• Tessa Y Le Large,
• Adam E Frampton,
• Christian Rolfo,
• Johannes Voortman,
• Elisa Giovannetti

The EGFR pathway regulates BCRP expression in NSCLC cells: role of erlotinib.

• Authors:
• Letizia Porcelli,
• Elisa Giovannetti,
• Yehuda G Assaraf,
• Gerrit Jansen,
• George L Scheffer,
• Ietje Kathman,
• Amalia Azzariti,
• Angelo Paradiso,
• Godefridus J Peters

Synergistic activity of the c-Met and tubulin inhibitor tivantinib (ARQ197) with pemetrexed in mesothelioma cells.

• Authors:
• Leticia G Leon,
• Maria Gemelli,
• Rocco Sciarrillo,
• Amir Avan,
• Niccola Funel,
• Elisa Giovannetti

MicroRNAs in Cancer Management: Big Challenges for Small Molecules.

• Authors:
• Paolo Gandellini,
• Elisa Giovannetti,
• Francesco Nicassio

Entrectinib: a potent new TRK, ROS1, and ALK inhibitor.

• Authors:
• Christian Rolfo,
• Rossana Ruiz,
• Elisa Giovannetti,
• Ignacio Gil-Bazo,
• Antonio Russo,
• Francesco Passiglia,
• Marco Giallombardo,
• Marc Peeters,
• Luis Raez

Circulating microRNAs as diagnostic biomarkers for pancreatic cancer.

• Authors:
• Tessa Y S Le Large,
• Laura L Meijer,
• Mireia Mato Prado,
• Geert Kazemier,
• Adam E Frampton,
• Elisa Giovannetti

c-Met as a Target for Personalized Therapy.

• Authors:
• Ingrid Garajová,
• Elisa Giovannetti,
• Guido Biasco,
• Godefridus J Peters

Overcoming crizotinib resistance in ALK-rearranged NSCLC with the second-generation ALK-inhibitor ceritinib.

• Authors:
• Ittai B Muller,
• Adrianus J De Langen,
• Richard J Honeywell,
• Elisa Giovannetti,
• Godefridus J Peters

MicroRNA profiling of primary pulmonary enteric adenocarcinoma in members from the same family reveals some similarities to pancreatic adenocarcinoma-a step towards personalized therapy.

• Authors:
• Ingrid Garajová,
• Niccola Funel,
• Michelangelo Fiorentino,
• Valentina Agostini,
• Manuela Ferracin,
• Massimo Negrini,
• Giovanni Luca Frassineti,
• Giampaolo Gavelli,
• Adam Enver Frampton,
• Guido Biasco,
• Elisa Giovannetti

On the pharmacogenetics of non-small cell lung cancer treatment.

• Authors:
• Mariacarmela Santarpia,
• Christian Rolfo,
• G J Peters,
• Leticia G Leon,
• Elisa Giovannetti

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition).

• Authors:
• Daniel J Klionsky,
• Kotb Abdelmohsen,
• Akihisa Abe,
• Md Joynal Abedin,
• Hagai Abeliovich,
• Abraham Acevedo Arozena,
• Hiroaki Adachi,
• Christopher M Adams,
• Peter D Adams,
• Khosrow Adeli,
• Peter J Adhihetty,
• Sharon G Adler,
• Galila Agam,
• Rajesh Agarwal,
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• Maria Agnello,
• Patrizia Agostinis,
• Patricia V Aguilar,
• Julio Aguirre-Ghiso,
• Edoardo M Airoldi,
• Slimane Ait-Si-Ali,
• Takahiko Akematsu,
• Emmanuel T Akporiaye,
• Mohamed Al-Rubeai,
• Guillermo M Albaiceta,
• Chris Albanese,
• Diego Albani,
• Matthew L Albert,
• Jesus Aldudo,
• Hana Algül,
• Mehrdad Alirezaei,
• Iraide Alloza,
• Alexandru Almasan,
• Maylin Almonte-Beceril,
• Emad S Alnemri,
• Covadonga Alonso,
• Nihal Altan-Bonnet,
• Dario C Altieri,
• Silvia Alvarez,
• Lydia Alvarez-Erviti,
• Sandro Alves,
• Giuseppina Amadoro,
• Atsuo Amano,
• Consuelo Amantini,
• Santiago Ambrosio,
• Ivano Amelio,
• Amal O Amer,
• Mohamed Amessou,
• Angelika Amon,
• Zhenyi An,
• Frank A Anania,
• Stig U Andersen,
• Usha P Andley,
• Catherine K Andreadi,
• Nathalie Andrieu-Abadie,
• Alberto Anel,
• David K Ann,
• Shailendra Anoopkumar-Dukie,
• Manuela Antonioli,
• Hiroshi Aoki,
• Nadezda Apostolova,
• Saveria Aquila,
• Katia Aquilano,
• Koichi Araki,
• Eli Arama,
• Agustin Aranda,
• Jun Araya,
• Alexandre Arcaro,
• Esperanza Arias,
• Hirokazu Arimoto,
• Aileen R Ariosa,
• Jane L Armstrong,
• Thierry Arnould,
• Ivica Arsov,
• Katsuhiko Asanuma,
• Valerie Askanas,
• Eric Asselin,
• Ryuichiro Atarashi,
• Sally S Atherton,
• Julie D Atkin,
• Laura D Attardi,
• Patrick Auberger,
• Georg Auburger,
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• Limor Avrahami,
• Suresh Awale,
• Neelam Azad,
• Tiziana Bachetti,
• Jonathan M Backer,
• Dong-Hun Bae,
• Jae-Sung Bae,
• Ok-Nam Bae,
• Soo Han Bae,
• Eric H Baehrecke,
• Seung-Hoon Baek,
• Stephen Baghdiguian,
• Agnieszka Bagniewska-Zadworna,
• Hua Bai,
• Jie Bai,
• Xue-Yuan Bai,
• Yannick Bailly,
• Kithiganahalli Narayanaswamy Balaji,
• Walter Balduini,
• Andrea Ballabio,
• Rena Balzan,
• Rajkumar Banerjee,
• Gábor Bánhegyi,
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• Amélie Bernard,
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• Viktor Billes,
• Claudia Bincoletto,
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• Sara W Bird,
• Marc Bitoun,
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• Craig Blackstone,
• Lionel Blanc,
• Guillermo A Blanco,
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• Stefan Böckler,
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• Alessandra Bolino,
• Andrea Boman,
• Paolo Bonaldo,
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• German Bou,
• Marina Bouché,
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• Claudio Brancolini,
• Gerhard H Braus,
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• Vladimir Bumbasirevic,
• Yan Burelle,
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• Margit Burmeister,
• Peter Bütikofer,
• Laura Caberlotto,
• Ken Cadwell,
• Monika Cahova,
• Dongsheng Cai,
• Jingjing Cai,
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• Sara Calatayud,
• Nadine Camougrand,
• Michelangelo Campanella,
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• Silvia Campello,
• Robin Candau,
• Isabella Caniggia,
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• Leticia Am Carneiro,
• Oliana Carnevali,
• Serena Carra,
• Alice Carrier,
• Bernadette Carroll,
• Caty Casas,
• Josefina Casas,
• Giuliana Cassinelli,
• Perrine Castets,
• Susana Castro-Obregon,
• Gabriella Cavallini,
• Isabella Ceccherini,
• Francesco Cecconi,
• Arthur I Cederbaum,
• Valentín Ceña,
• Simone Cenci,
• Claudia Cerella,
• Davide Cervia,
• Silvia Cetrullo,
• Hassan Chaachouay,
• Han-Jung Chae,
• Andrei S Chagin,
• Chee-Yin Chai,
• Gopal Chakrabarti,
• Georgios Chamilos,
• Edmond Yw Chan,
• Matthew Tv Chan,
• Dhyan Chandra,
• Pallavi Chandra,
• Chih-Peng Chang,
• Raymond Chuen-Chung Chang,
• Ta Yuan Chang,
• John C Chatham,
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• Santosh Chauhan,
• Yongsheng Che,
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• Rajkumar Cheluvappa,
• Chun-Jung Chen,
• Gang Chen,
• Guang-Chao Chen,
• Guoqiang Chen,
• Hongzhuan Chen,
• Jeff W Chen,
• Jian-Kang Chen,
• Min Chen,
• Mingzhou Chen,
• Peiwen Chen,
• Qi Chen,
• Quan Chen,
• Shang-Der Chen,
• Si Chen,
• Steve S-L Chen,
• Wei Chen,
• Wei-Jung Chen,
• Wen Qiang Chen,
• Wenli Chen,
• Xiangmei Chen,
• Yau-Hung Chen,
• Ye-Guang Chen,
• Yin Chen,
• Yingyu Chen,
• Yongshun Chen,
• Yu-Jen Chen,
• Yue-Qin Chen,
• Yujie Chen,
• Zhen Chen,
• Zhong Chen,
• Alan Cheng,
• Christopher Hk Cheng,
• Hua Cheng,
• Heesun Cheong,
• Sara Cherry,
• Jason Chesney,
• Chun Hei Antonio Cheung,
• Eric Chevet,
• Hsiang Cheng Chi,
• Sung-Gil Chi,
• Fulvio Chiacchiera,
• Hui-Ling Chiang,
• Roberto Chiarelli,
• Mario Chiariello,
• Marcello Chieppa,
• Lih-Shen Chin,
• Mario Chiong,
• Gigi Nc Chiu,
• Dong-Hyung Cho,
• Ssang-Goo Cho,
• William C Cho,
• Yong-Yeon Cho,
• Young-Seok Cho,
• Augustine Mk Choi,
• Eui-Ju Choi,
• Eun-Kyoung Choi,
• Jayoung Choi,
• Mary E Choi,
• Seung-Il Choi,
• Tsui-Fen Chou,
• Salem Chouaib,
• Divaker Choubey,
• Vinay Choubey,
• Kuan-Chih Chow,
• Kamal Chowdhury,
• Charleen T Chu,
• Tsung-Hsien Chuang,
• Taehoon Chun,
• Hyewon Chung,
• Taijoon Chung,
• Yuen-Li Chung,
• Yong-Joon Chwae,
• Valentina Cianfanelli,
• Roberto Ciarcia,
• Iwona A Ciechomska,
• Maria Rosa Ciriolo,
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• Marcello D'Amelio,
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• Paula Daza,
• Jackie de Belleroche,
• Paul de Figueiredo,
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• José de la Fuente,
• Luisa De Martino,
• Antonella De Matteis,
• Guido Ry De Meyer,
• Angelo De Milito,
• Mauro De Santi,
• Wanderley de Souza,
• Vincenzo De Tata,
• Daniela De Zio,
• Jayanta Debnath,
• Reinhard Dechant,
• Jean-Paul Decuypere,
• Shane Deegan,
• Benjamin Dehay,
• Barbara Del Bello,
• Dominic P Del Re,
• Régis Delage-Mourroux,
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• Louise Deldicque,
• Elizabeth Delorme-Axford,
• Yizhen Deng,
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• Antonio Di Pietro,
• Livia Di Renzo,
• Aaron DiAntonio,
• Guillermo Díaz-Araya,
• Ines Díaz-Laviada,
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• Luciana Dini,
• Jörg Hw Distler,
• Abhinav Diwan,
• Mojgan Djavaheri-Mergny,
• Kostyantyn Dmytruk,
• Renwick Cj Dobson,
• Volker Doetsch,
• Karol Dokladny,
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• Massimo Donadelli,
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• Xiaonan Dong,
• Zheng Dong,
• Terrence M Donohue,
• Kelly S Doran,
• Gabriella D'Orazi,
• Gerald W Dorn,
• Victor Dosenko,
• Sami Dridi,
• Liat Drucker,
• Jie Du,
• Li-Lin Du,
• Lihuan Du,
• André du Toit,
• Priyamvada Dua,
• Lei Duan,
• Pu Duann,
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• Umamaheswar Duvvuri,
• Vinay Eapen,
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• Hagit Eldar-Finkelman,
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• Jekaterina Erenpreisa,
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• Eeva-Liisa Eskelinen,
• Lucile Espert,
• Lorena Esteban-Martínez,
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• Mario Fabri,
• Gemma Fabrias,
• Cinzia Fabrizi,
• Antonio Facchiano,
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• Chunhai Fan,
• Daping Fan,
• Jie Fan,
• Shengyun Fang,
• Manolis Fanto,
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• Salvatore Florio,
• R Andres Floto,
• Marco Folini,
• Carlo Follo,
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• Francesco Fornai,
• Franco Fortunato,
• Alessandro Fraldi,
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• Yuuki Fujiwara,
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• Simone Fulda,
• Carmela Fusco,
• Bozena Gabryel,
• Matthias Gaestel,
• Philippe Gailly,
• Malgorzata Gajewska,
• Sehamuddin Galadari,
• Gad Galili,
• Inmaculada Galindo,
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• Giovanna Galliciotti,
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• Monique Gannagé,
• Fen-Biao Gao,
• Feng Gao,
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• Lorena García Nannig,
• Eleonora García Véscovi,
• Marina Garcia-Macía,
• Carmen Garcia-Ruiz,
• Abhishek D Garg,
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• Ricardo Gargini,
• Nils Christian Gassen,
• Damián Gatica,
• Evelina Gatti,
• Julie Gavard,
• Evripidis Gavathiotis,
• Liang Ge,
• Pengfei Ge,
• Shengfang Ge,
• Po-Wu Gean,
• Vania Gelmetti,
• Armando A Genazzani,
• Jiefei Geng,
• Pascal Genschik,
• Lisa Gerner,
• Jason E Gestwicki,
• David A Gewirtz,
• Saeid Ghavami,
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• Debabrata Ghosh,
• Anna Maria Giammarioli,
• Francesca Giampieri,
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• Alexandra Giatromanolaki,
• Derrick J Gibbings,
• Lara Gibellini,
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• Vanessa Ginet,
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• Flaviano Giorgini,
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• Sandy Giuliano,
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• Alvaro Glavic,
• Martin Gleave,
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• Candelaria Gomez-Manzano,
• Rubén Gómez-Sánchez,
• Dawit Ap Gonçalves,
• Ebru Goncu,
• Qingqiu Gong,
• Céline Gongora,
• Carlos B Gonzalez,
• Pedro Gonzalez-Alegre,
• Pilar Gonzalez-Cabo,
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• Ing Swie Goping,
• Carlos Gorbea,
• Nikolai V Gorbunov,
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• Sharon M Gorski,
• Sandro Goruppi,
• Shino Goto-Yamada,
• Cecilia Gotor,
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• Illana Gozes,
• Devrim Gozuacik,
• Yacine Graba,
• Martin Graef,
• Giovanna E Granato,
• Gary Dean Grant,
• Steven Grant,
• Giovanni Luca Gravina,
• Douglas R Green,
• Alexander Greenhough,
• Michael T Greenwood,
• Benedetto Grimaldi,
• Frédéric Gros,
• Charles Grose,
• Jean-Francois Groulx,
• Florian Gruber,
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