Publications

Double Trouble: A Case Series on Concomitant Genetic Aberrations in NSCLC.
Clin Lung Cancer 2018 Jan 6;19(1):35-41. Epub 2017 Jul 6.
Center for Oncological Research, University of Antwerp, Antwerp, Belgium; Phase I - Early Clinical Trials Unit, Oncology Department, Antwerp University Hospital, Antwerp, Belgium. Electronic address:

Swarm Intelligence-Enhanced Detection of Non-Small-Cell Lung Cancer Using Tumor-Educated Platelets.
Cancer Cell 2017 Aug;32(2):238-252.e9
Department of Neurosurgery, VU University Medical Center, Cancer Center Amsterdam, De Boelelaan 1117, 1081 HV Amsterdam, the Netherlands; Brain Tumor Center Amsterdam, VU University Medical Center, Cancer Center Amsterdam, De Boelelaan 1117, 1081 HV Amsterdam, the Netherlands; Department of Neurology, Massachusetts General Hospital and Neuroscience Program, Harvard Medical School, 149 13(th) Street, Charlestown, MA 02129, USA. Electronic address:


A mechanopharmacology approach to overcome chemoresistance in pancreatic cancer.
Drug Resist Updat 2017 Mar 24;31:43-51. Epub 2017 Jul 24.
Department of Medical Oncology, VU University Medical Center Amsterdam, Amsterdam, The Netherlands; Cancer Pharmacology Lab, AIRC Start-Up Unit, University Hospital of Pisa, Pisa, Italy; Institute for Nanoscience and Nanotechnologies, CNR-Nano, Pisa. Electronic address:

Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors and Chemotherapy: A Glimmer of Hope?
J Clin Oncol 2017 Feb 5;35(6):692-693. Epub 2016 Dec 5.
Nele Van Der Steen, Antwerp University Hospital, University of Antwerp, Antwerp, Belgium; and VU Medical Center, Amsterdam, the Netherlands; Christian Diego Rolfo and Patrick Pauwels, Antwerp University Hospital, University of Antwerp, Antwerp, Belgium; Godefridus J. Peters, VU Medical Center, Amsterdam, the Netherlands; and Elisa Giovannetti, VU Medical Center, Amsterdam, The Netherlands; and University of Pisa, Pisa, Italy.

Better to be alone than in bad company: The antagonistic effect of cisplatin and crizotinib combination therapy in non-small cell lung cancer.
World J Clin Oncol 2016 Dec;7(6):425-432
Nele Van Der Steen, Christophe Deben, Vanessa Deschoolmeester, An Wouters, Filip Lardon, Christian Rolfo, Paul Germonpré, Patrick Pauwels, Center for Oncological Research, University of Antwerp, 2610 Wilrijk, Belgium.

Using RNA-sequencing to Detect Novel Splice Variants Related to Drug Resistance in In Vitro Cancer Models.
J Vis Exp 2016 Dec 9(118). Epub 2016 Dec 9.
Department of Medical Oncology, VU University Medical Center; Cancer Pharmacology Lab, AIRC Start-Up Unit, University of Pisa; Institute of Nanoscience and Nanotechnology, CNR-Nano;






microRNAs with prognostic significance in pancreatic ductal adenocarcinoma: A meta-analysis.
Eur J Cancer 2015 Jul 19;51(11):1389-404. Epub 2015 May 19.
Division of Oncology, Dept. of Surgery & Cancer, Imperial Centre for Translational and Experimental Medicine (ICTEM), Imperial College, Hammersmith Hospital campus, Du Cane Road, London W12 0NN, UK. Electronic address:

Platinum-induced neurotoxicity and preventive strategies: past, present, and future.
Oncologist 2015 Apr 12;20(4):411-32. Epub 2015 Mar 12.
Departments of Medical Oncology and Neurology, VU University Medical Center, Amsterdam, The Netherlands; Department of Surgery and Translational Medicine, University of Milano-Bicocca, Monza, Italy; Department of New Sciences and Technology, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran






Role of CYB5A in pancreatic cancer prognosis and autophagy modulation.
J Natl Cancer Inst 2014 Jan 3;106(1):djt346. Epub 2013 Dec 3.
Affiliations of authors: Department of Medical Oncology (EG, AA, GJP) and Department of Neurosurgery (TL, VC, TW), VU University Medical Center, and Centre for Integrative Bioinformatics (AvdV), VU University, Amsterdam, the Netherlands; Department of Ricerca Traslazionale e delle Nuove Tecnologie in Medicina e Chirurgia, University of Pisa, Pisa, Italy (NF, UB, EV); Department of Neurology, Stanford University, Stanford, CA (VC); Department of Neurology, Massachusetts General Hospital and Neuroscience Program, Harvard Medical School, Boston, MA (TW); Medical Oncology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD (QW, J-HL, YW, GG).

Crizotinib inhibits metabolic inactivation of gemcitabine in c-Met-driven pancreatic carcinoma.
Cancer Res 2013 Nov 1;73(22):6745-56. Epub 2013 Oct 1.
Authors' Affiliations: Departments of Medical Oncology, Hematology, Neurosurgery and Pediatric Oncology/Hematology, Neuro-oncology Research Group, VU University Medical Center; Diagnostic Oncology Division, Netherlands Cancer Institute; VisualSonics, Amsterdam, the Netherlands; Departments of Neurology and Pediatrics, Stanford University School of Medicine, Stanford, California; Division of Surgical Pathology, Division of General and Transplant Surgery, University of Pisa, Pisa, Italy; and Molecular Neurogenetics Unit, Department of Neurology, Massachusetts General Hospital and Neuroscience Program, Harvard Medical School, Boston, Massachusetts.

Serum miR-1290 as a marker of pancreatic cancer--letter.
Clin Cancer Res 2013 Sep 25;19(18):5250-1. Epub 2013 Jul 25.
Authors' Affiliations: HPB Surgical Unit and Division of Oncology, Department of Surgery & Cancer, Imperial College, Hammersmith Hospital campus, London, United Kingdom; and Departments of Surgery and Medical Oncology, VU University Medical Center, Amsterdam, the Netherlands.


MAPK p38 and JNK have opposing activities on TRAIL-induced apoptosis activation in NSCLC H460 cells that involves RIP1 and caspase-8 and is mediated by Mcl-1.
Apoptosis 2013 Jul;18(7):851-60
Department of Medical Oncology, University of Groningen, University Medical Center Groningen, Hanzeplein 1, Groningen 9713 GZ, The Netherlands.

Chemotherapy, targeted agents, antiemetics and growth-factors in human milk: how should we counsel cancer patients about breastfeeding?
Cancer Treat Rev 2013 May 28;39(3):207-11. Epub 2012 Nov 28.
Fertility and Procreation in Oncology Unit, Department of Medicine, European Institute of Oncology, Milan, Italy.






Impact of microRNAs in resistance to chemotherapy and novel targeted agents in non-small cell lung cancer.
Curr Pharm Biotechnol 2014 ;15(5):475-85
Department of Medical Oncology, VU University Medical Center, Cancer Center Amsterdam, CCA room 1.42, De Boelelaan 1117, 1081 HV Amsterdam, The Netherlands.



AKT1 and SELP polymorphisms predict the risk of developing cachexia in pancreatic cancer patients.
PLoS One 2014 19;9(9):e108057. Epub 2014 Sep 19.
Department of Medical Oncology, VU University Medical Center, Amsterdam, The Netherlands; Start-Up Unit, University of Pisa, Pisa, Italy.

Molecular mechanisms underlying the role of microRNAs in the chemoresistance of pancreatic cancer.
Biomed Res Int 2014 28;2014:678401. Epub 2014 Aug 28.
Department of Medical Oncology, VU University Medical Center, Cancer Center Amsterdam, De Boelelaan 1117, 1081 HV Amsterdam, The Netherlands ; Start-Up Unit, University of Pisa, Lungarno Pacinotti 43, 56126 Pisa, Italy.


Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition).
Autophagy 2016 ;12(1):1-222
kb Emory University, School of Medicine , Department of Microbiology and Immunology , Atlanta , GA , USA.

The potential of neurotrophic tyrosine kinase (NTRK) inhibitors for treating lung cancer.
Expert Opin Investig Drugs 2016 24;25(4):385-92. Epub 2016 Feb 24.
d Phase I-Early Clinical Trials Unit, Oncology Department , Antwerp University Hospital (UZA) and Center for Oncological Research (CORE) Antwerp University , Edegem , Antwerp , Belgium.


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