Elin Lehrmann

Elin Lehrmann

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Elin Lehrmann

Elin Lehrmann

Publications by authors named "Elin Lehrmann"

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62Publications

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Multidimensional informatic deconvolution defines gender-specific roles of hypothalamic GIT2 in aging trajectories.

Mech Ageing Dev 2019 Dec 28;184:111150. Epub 2019 Sep 28.

Receptor Biology Lab, Department of Biomedical Sciences, University of Antwerp, 2610, Wilrijk, Belgium; Receptor Pharmacology Unit, Laboratory of Neuroscience, National Institute on Aging, National Institutes of Health, Biomedical Research Center, 251 Bayview Boulevard, Baltimore, MD, 21224, United States. Electronic address:

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http://dx.doi.org/10.1016/j.mad.2019.111150DOI Listing
December 2019

Hydroxyurea attenuates oxidative, metabolic, and excitotoxic stress in rat hippocampal neurons and improves spatial memory in a mouse model of Alzheimer's disease.

Neurobiol Aging 2018 12 29;72:121-133. Epub 2018 Aug 29.

Laboratory of Neurosciences, National Institute on Aging Intramural Research Program, Baltimore, MD, USA. Electronic address:

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http://dx.doi.org/10.1016/j.neurobiolaging.2018.08.021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6215724PMC
December 2018

Eda-activated RelB recruits an SWI/SNF (BAF) chromatin-remodeling complex and initiates gene transcription in skin appendage formation.

Proc Natl Acad Sci U S A 2018 08 23;115(32):8173-8178. Epub 2018 Jul 23.

Laboratory of Genetics and Genomics, National Institute on Aging/NIH-Intramural Research Program, Baltimore, MD 21224;

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http://dx.doi.org/10.1073/pnas.1800930115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6094125PMC
August 2018

Transcriptome States Reflect Imaging of Aging States.

J Gerontol A Biol Sci Med Sci 2018 06;73(7):893-901

Laboratory of Genetics and Genomics, Biomedical Research Center, Baltimore, Maryland.

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http://dx.doi.org/10.1093/gerona/glx236DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6001903PMC
June 2018

MicroRNAs Modulate Oxidative Stress in Hypertension through PARP-1 Regulation.

Oxid Med Cell Longev 2017 4;2017:3984280. Epub 2017 Jun 4.

Laboratory of Epidemiology and Population Science, National Institute on Aging, National Institutes of Health, 251 Bayview Boulevard, Baltimore, MD 21224, USA.

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http://dx.doi.org/10.1155/2017/3984280DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5474262PMC
March 2018

Elongator and codon bias regulate protein levels in mammalian peripheral neurons.

Nat Commun 2018 03 1;9(1):889. Epub 2018 Mar 1.

Department of Biological and Physical Sciences, Montana State University Billings, Billings, MT, 59101, USA.

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http://dx.doi.org/10.1038/s41467-018-03221-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5832791PMC
March 2018

LncRNA OIP5-AS1/cyrano suppresses GAK expression to control mitosis.

Oncotarget 2017 Jul;8(30):49409-49420

Laboratory of Genetics and Genomics, National Institute on Aging-Intramural Research Program, NIH, Baltimore, MD 21224, USA.

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http://dx.doi.org/10.18632/oncotarget.17219DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5564778PMC
July 2017

Serum extracellular vesicle depletion processes affect release and infectivity of HIV-1 in culture.

Sci Rep 2017 05 31;7(1):2558. Epub 2017 May 31.

Department of Molecular and Comparative Pathobiology, The Johns Hopkins University School of Medicine, Baltimore, MD, United States.

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http://dx.doi.org/10.1038/s41598-017-02908-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5451420PMC
May 2017

Mild traumatic brain injury-induced hippocampal gene expressions: The identification of target cellular processes for drug development.

J Neurosci Methods 2016 10 8;272:4-18. Epub 2016 Feb 8.

Translational Gerontology Branch, Intramural Research Program, National Institute on Aging, National Institutes of Health, Baltimore, MD 21224, USA.

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http://dx.doi.org/10.1016/j.jneumeth.2016.02.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4977213PMC
October 2016

Novel RNA-binding activity of NQO1 promotes SERPINA1 mRNA translation.

Free Radic Biol Med 2016 10 8;99:225-233. Epub 2016 Aug 8.

Experimental Gerontology Section, Translational Gerontology Branch, National Institute on Aging, 251 Bayview Blvd., Suite 100, Baltimore, MD 21224, USA. Electronic address:

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http://dx.doi.org/10.1016/j.freeradbiomed.2016.08.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5107118PMC
October 2016

RPTOR, a novel target of miR-155, elicits a fibrotic phenotype of cystic fibrosis lung epithelium by upregulating CTGF.

RNA Biol 2016 09 10;13(9):837-47. Epub 2016 Jun 10.

b Department of Anatomy , Physiology and Genetics, Uniformed Services University of the Health Sciences , Bethesda , MD , USA.

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http://dx.doi.org/10.1080/15476286.2016.1197484DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5013987PMC
September 2016

GIT2 Acts as a Systems-Level Coordinator of Neurometabolic Activity and Pathophysiological Aging.

Front Endocrinol (Lausanne) 2015 18;6:191. Epub 2016 Jan 18.

Receptor Pharmacology Unit, National Institute on Aging, National Institutes of Health, Baltimore, MD, USA; Translational Neurobiology Group, VIB Department of Molecular Genetics, University of Antwerp, Antwerp, Belgium; Laboratory of Neurogenetics, Institute Born-Bunge, University of Antwerp, Antwerp, Belgium.

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http://dx.doi.org/10.3389/fendo.2015.00191DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4716144PMC
February 2016

Delineation of a conserved arrestin-biased signaling repertoire in vivo.

Mol Pharmacol 2015 Apr 30;87(4):706-17. Epub 2015 Jan 30.

National Institutes of Health, National Institute on Aging, Baltimore, Maryland (S.M., B.M., S.P., K.G.B., W.H.W., Y.Z., E.L.); Department of Medicine, Duke University Medical Center, Durham, North Carolina (D.G.-P.); National Institutes of Health, Center for Information Technology, Bethesda, Maryland (H.C., C.J.); Department of Medicine and Department of Biochemistry and Molecular Biology, Medical University of South Carolina, Charleston, South Carolina (L.M.L.); and Ralph H. Johnson Veterans Affairs Medical Center, Charleston, South Carolina (L.M.L.).

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http://molpharm.aspetjournals.org/content/87/4/706.full.pdf
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http://molpharm.aspetjournals.org/cgi/doi/10.1124/mol.114.09
Publisher Site
http://dx.doi.org/10.1124/mol.114.095224DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4366796PMC
April 2015

Enhanced upregulation of CRH mRNA expression in the nucleus accumbens of male rats after a second injection of methamphetamine given thirty days later.

PLoS One 2014 27;9(1):e84665. Epub 2014 Jan 27.

Molecular Neuropsychiatry Research Branch, Intramural Research Program, National Institute on Drug Abuse, National Institutes of Health, Baltimore, Maryland, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0084665PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3903495PMC
November 2014

Down-regulation of eIF4GII by miR-520c-3p represses diffuse large B cell lymphoma development.

PLoS Genet 2014 Jan 30;10(1):e1004105. Epub 2014 Jan 30.

Marlene & Stewart Greenebaum Cancer Center, Department of Medicine, University of Maryland, Baltimore, Maryland, United States of America ; Veterans Administration Medical Center, Baltimore, Maryland, United States of America.

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http://dx.doi.org/10.1371/journal.pgen.1004105DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3907297PMC
January 2014

Cancer-produced metabolites of 5-lipoxygenase induce tumor-evoked regulatory B cells via peroxisome proliferator-activated receptor α.

J Immunol 2013 Mar 13;190(6):2575-84. Epub 2013 Feb 13.

Immunoregulation Section, Laboratory of Molecular Biology and Immunology, National Institute on Aging, Baltimore, MD 21224, USA.

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http://dx.doi.org/10.4049/jimmunol.1201920DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3594535PMC
March 2013

Toll-like receptor 2 (TLR2)-TLR9 crosstalk dictates IL-12 family cytokine production in microglia.

Glia 2012 Jan 7;60(1):29-42. Epub 2011 Sep 7.

Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, Nebraska 68198-5900, USA.

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http://dx.doi.org/10.1002/glia.21243DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3217087PMC
January 2012

FACS purification of immunolabeled cell types from adult rat brain.

J Neurosci Methods 2012 Jan 3;203(1):10-8. Epub 2011 Sep 3.

Behavioral Neuroscience Branch, IRP/NIDA/NIH/DHHS, 251 Bayview Boulevard, Baltimore, MD 21224, USA.

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http://dx.doi.org/10.1016/j.jneumeth.2011.08.045DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3221768PMC
January 2012

Altered gene expression in pulmonary tissue of tryptophan hydroxylase-1 knockout mice: implications for pulmonary arterial hypertension.

PLoS One 2011 Mar 25;6(3):e17735. Epub 2011 Mar 25.

Translational Pharmacology Section, Intramural Research Program, National Institute on Drug Abuse, National Institutes of Health, Baltimore, Maryland, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0017735PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3064573PMC
March 2011

Methamphetamine-induced dopamine-independent alterations in striatal gene expression in the 6-hydroxydopamine hemiparkinsonian rats.

PLoS One 2010 Dec 13;5(12):e15643. Epub 2010 Dec 13.

Molecular Neuropsychiatry Research Branch, Intramural Research Program, National Institute on Drug Abuse/National Institutes of Health/Department of Health and Human Services, Baltimore, Maryland, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0015643PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3001483PMC
December 2010

Gene expression profiling reveals distinct cocaine-responsive genes in human fetal CNS cell types.

J Addict Med 2009 Dec;3(4):218-26

Cellular Neurobiology Research Branch (CTL, EL, TH, RA, SYT, JC, JFS, WJF), Intramural Research Program (IRP), National Institute on Drug Abuse (NIDA), National Institutes of Health (NIH), Department of Health and Human Services (DHHS), Baltimore, MD; the ScienCell Research Laboratories (JS), San Diego, CA, and the Gene Expression and Genomics Unit (KGB), IRP, National Institute on Aging (NIA), NIH, DHHS, Baltimore, MD.

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http://dx.doi.org/10.1097/ADM.0b013e318199d863DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2952961PMC
December 2009

Transcriptional correlates of human substance use.

Ann N Y Acad Sci 2008 Oct;1139:34-42

Cellular Neurobiology Research Branch, National Institute on Drug Abuse, National Institutes of Health, Department of Health and Human Services, Baltimore, Maryland, USA.

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http://dx.doi.org/10.1196/annals.1432.027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2593736PMC
October 2008

Postmortem diagnosis and toxicological validation of illicit substance use.

Addict Biol 2008 Mar 14;13(1):105-17. Epub 2008 Jan 14.

Cellular Neurobiology Research Branch, National Institute on Drug Abuse (NIDA IRP), National Institutes of Health, Baltimore, MD 21224, USA.

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http://dx.doi.org/10.1111/j.1369-1600.2007.00085.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2639787PMC
March 2008

Glial activation precedes seizures and hippocampal neurodegeneration in measles virus-infected mice.

Epilepsia 2008 ;49 Suppl 2:13-23

Maryland Psychiatric Research Center, University of Maryland School of Medicine, Baltimore, Maryland 21228, USA.

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http://doi.wiley.com/10.1111/j.1528-1167.2008.01489.x
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http://dx.doi.org/10.1111/j.1528-1167.2008.01489.xDOI Listing
March 2008

Role of heparin binding growth factors in nigrostriatal dopamine system development and Parkinson's disease.

Brain Res 2007 May 22;1147:77-88. Epub 2007 Feb 22.

Dept. Neurological Sciences, Rush University Medical Center, Chicago, IL 60612, USA.

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http://dx.doi.org/10.1016/j.brainres.2007.02.028DOI Listing
May 2007

Microarray analysis of oxidative stress regulated genes in mesencephalic dopaminergic neuronal cells: relevance to oxidative damage in Parkinson's disease.

Neurochem Int 2007 May 23;50(6):834-47. Epub 2007 Feb 23.

Parkinson's Disorder Research Laboratory, Iowa Center for Advanced Neurotoxicology, Department of Biomedical Sciences, Iowa State University, Ames, IA 50011-1250, USA.

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http://dx.doi.org/10.1016/j.neuint.2007.02.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1950670PMC
May 2007

Transcriptional changes common to human cocaine, cannabis and phencyclidine abuse.

PLoS One 2006 Dec 27;1:e114. Epub 2006 Dec 27.

Cellular Neurobiology Research Branch and Chemistry and Drug Metabolism Section, National Institute on Drug Abuse (NIDA) Intramural Research Program, National Institutes of Health, Department of Health and Human Services, Baltimore, Maryland, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0000114PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1762434PMC
December 2006

A validated positive chemical ionization GC/MS method for the identification and quantification of amphetamine, opiates, cocaine, and metabolites in human postmortem brain.

J Mass Spectrom 2006 Feb;41(2):175-84

Chemistry and Drug Metabolism Section, Intramural Research Program, National Institute on Drug Abuse, NIH, DHHS, 5500 Nathan Shock Drive, Baltimore, MD 21224, USA.

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http://dx.doi.org/10.1002/jms.975DOI Listing
February 2006