Elin Borgen

Baseline microvessel density predicts response to neoadjuvant bevacizumab treatment of locally advanced breast cancer.

Authors:

Kristi Krüger Laxmi Silwal-Pandit Elisabeth Wik Oddbjørn Straume Ingunn M Stefansson Elin Borgen Øystein Garred Bjørn Naume Olav Engebraaten Lars A Akslen

Sci Rep 2021 Feb 9;11(1):3388. Epub 2021 Feb 9.

Centre for Cancer Biomarkers CCBIO, Department of Clinical Medicine, Section for Pathology, Haukeland University Hospital, University of Bergen, Bergen, Norway.

View Article and Find Full Text PDF

February 2021

Preoperative CTC-Detection by CellSearch Is Associated with Early Distant Metastasis and Impaired Survival in Resected Pancreatic Cancer.

Authors:

Harald Hugenschmidt Knut Jørgen Labori Elin Borgen Cathrine Brunborg Cecilie Bendigtsen Schirmer Lars Thomas Seeberg Bjørn Naume Gro Wiedswang

Cancers (Basel) 2021 Jan 27;13(3). Epub 2021 Jan 27.

Department of Gastrointestinal Surgery, Oslo University Hospital, 0424 Oslo, Norway.

View Article and Find Full Text PDF

January 2021

Coagulation factor V is a marker of tumor-infiltrating immune cells in breast cancer.

Authors:

Mari Tinholt Benedicte Stavik Xavier Tekpli Øystein Garred Elin Borgen Vessela Kristensen Kristine Kleivi Sahlberg Per Morten Sandset Nina Iversen

Oncoimmunology 2020 09 29;9(1):1824644. Epub 2020 Sep 29.

Department of Medical Genetics, Oslo University Hospital, Oslo, Norway.

View Article and Find Full Text PDF

September 2020

Low Z-4OHtam concentrations are associated with adverse clinical outcome among early stage premenopausal breast cancer patients treated with adjuvant tamoxifen.

Authors:

Thomas Helland Bjørn Naume Steinar Hustad Ersilia Bifulco Jan Terje Kvaløy Anna Barbro Saetersdal Marit Synnestvedt Tone Hoel Lende Bjørnar Gilje Ingvil Mjaaland Kjetil Weyde Egil Støre Blix Gro Wiedswang Elin Borgen Daniel Louis Hertz Emiel Adrianus Maria Janssen Gunnar Mellgren Håvard Søiland

Mol Oncol 2020 Nov 30. Epub 2020 Nov 30.

Department of Clinical Science, University of Bergen, Norway.

View Article and Find Full Text PDF

November 2020

Cytokeratin-positive cells in the bone marrow from patients with pancreatic, periampullary malignancy and benign pancreatic disease show no prognostic information.

Authors:

Harald Hugenschmidt Knut Jørgen Labori Cathrine Brunborg Caroline Sophie Verbeke Lars Thomas Seeberg Cecilie Bendigtsen Schirmer Anne Renolen Elin Borgen Bjørn Naume Gro Wiedswang

BMC Cancer 2020 Nov 16;20(1):1107. Epub 2020 Nov 16.

Department of Gastrointestinal Surgery, Oslo University Hospital, Oslo, Norway.

View Article and Find Full Text PDF

November 2020

Immune phenotype of tumor microenvironment predicts response to bevacizumab in neoadjuvant treatment of ER-positive breast cancer.

Authors:

Hedda von der Lippe Gythfeldt Tonje Lien Xavier Tekpli Laxmi Silwal-Pandit Elin Borgen Øystein Garred Helle Skjerven Ellen Schlichting Steinar Lundgren Erik Wist Bjørn Naume Vessela Kristensen Anne-Lise Børresen-Dale Ole Christian Lingjaerde Olav Engebraaten

Int J Cancer 2020 Nov 18;147(9):2515-2525. Epub 2020 Jun 18.

Department of Oncology, Oslo University Hospital, Oslo, Norway.

View Article and Find Full Text PDF

November 2020

An independent poor-prognosis subtype of breast cancer defined by a distinct tumor immune microenvironment.

Nat Commun 2019 12 3;10(1):5499. Epub 2019 Dec 3.

Department of Cancer Genetics, Institute for Cancer Research, Oslo University Hospital, Oslo, Norway.

View Article and Find Full Text PDF

December 2019

Assessing Treatment Response and Prognosis by Serum and Tissue Metabolomics in Breast Cancer Patients.

Authors:

Julia Debik Leslie R Euceda Steinar Lundgren Hedda von der Lippe Gythfeldt Øystein Garred Elin Borgen Olav Engebraaten Tone F Bathen Guro F Giskeødegård

J Proteome Res 2019 10 16;18(10):3649-3660. Epub 2019 Sep 16.

Department of Oncology , Oslo University Hospital , 0424 Oslo , Norway.

View Article and Find Full Text PDF

October 2019

Serum levels of inflammation-related markers and metabolites predict response to neoadjuvant chemotherapy with and without bevacizumab in breast cancers.

Authors:

Marianne E Nome Leslie R Euceda Shakila Jabeen Julia Debik Tone F Bathen Guro F Giskeødegård Kristin A Taskén Gunhild M Maelandsmo Bente Halvorsen Arne Yndestad Elin Borgen Øystein Garred Pål Aukrust Thor Ueland Olav Engebraaten Vessela N Kristensen Xavier Tekpli

Int J Cancer 2020 01 8;146(1):223-235. Epub 2019 Oct 8.

Department of Clinical Molecular Biology, Division of Medicine, Akershus University Hospital, Lørenskog, Norway.

View Article and Find Full Text PDF

January 2020

Toward Personalized Computer Simulation of Breast Cancer Treatment: A Multiscale Pharmacokinetic and Pharmacodynamic Model Informed by Multitype Patient Data.

Authors:

Xiaoran Lai Oliver M Geier Thomas Fleischer Øystein Garred Elin Borgen Simon W Funke Surendra Kumar Marie E Rognes Therese Seierstad Anne-Lise Børresen-Dale Vessela N Kristensen Olav Engebraaten Alvaro Köhn-Luque Arnoldo Frigessi

Cancer Res 2019 08 22;79(16):4293-4304. Epub 2019 May 22.

Oslo Centre for Biostatistics and Epidemiology, Faculty of Medicine, University of Oslo, Oslo, Norway.

View Article and Find Full Text PDF

August 2019

Breast cancer quantitative proteome and proteogenomic landscape.

Nat Commun 2019 04 8;10(1):1600. Epub 2019 Apr 8.

Science for Life Laboratory, Department of Oncology-Pathology, Karolinska Institutet, 171 21, Solna, Sweden.

View Article and Find Full Text PDF

April 2019

Time series analysis of neoadjuvant chemotherapy and bevacizumab-treated breast carcinomas reveals a systemic shift in genomic aberrations.

Authors:

Elen Kristine Höglander Silje Nord David C Wedge Ole Christian Lingjærde Laxmi Silwal-Pandit Hedda vdL Gythfeldt Hans Kristian Moen Vollan Thomas Fleischer Marit Krohn Ellen Schlitchting Elin Borgen Øystein Garred Marit M Holmen Erik Wist Bjørn Naume Peter Van Loo Anne-Lise Børresen-Dale Olav Engebraaten Vessela Kristensen

Genome Med 2018 11 29;10(1):92. Epub 2018 Nov 29.

Department of Genetics, Institute for Cancer Research, Oslo University Hospital Radiumhospitalet, Postboks 4953 Nydalen, 0424, Oslo, Norway.

View Article and Find Full Text PDF

November 2018

NR2F1 stratifies dormant disseminated tumor cells in breast cancer patients.

Authors:

Elin Borgen Maria C Rypdal Maria Soledad Sosa Anne Renolen Ellen Schlichting Per E Lønning Marit Synnestvedt Julio A Aguirre-Ghiso Bjørn Naume

Breast Cancer Res 2018 10 16;20(1):120. Epub 2018 Oct 16.

Department of Oncology, Oslo University Hospital, Oslo, Norway.

View Article and Find Full Text PDF

October 2018

Circulating Tumor Cells are an Independent Predictor of Shorter Survival in Patients Undergoing Resection for Pancreatic and Periampullary Adenocarcinoma.

Authors:

Harald Hugenschmidt Knut Jørgen Labori Cathrine Brunborg Caroline Sophie Verbeke Lars Thomas Seeberg Cecilie Bendigtsen Schirmer Anne Renolen Elin Faye Borgen Bjørn Naume Gro Wiedswang

Ann Surg 2020 03;271(3):549-558

Department of GI-Surgery, Division of Surgery and Oncology, Oslo University Hospital, Oslo, Norway.

View Article and Find Full Text PDF

March 2020

Circulating Tumor Cells in Breast Cancer Patients Treated by Neoadjuvant Chemotherapy: A Meta-analysis.

Authors:

François-Clément Bidard Stefan Michiels Sabine Riethdorf Volkmar Mueller Laura J Esserman Anthony Lucci Bjørn Naume Jun Horiguchi Rafael Gisbert-Criado Stefan Sleijfer Masakazu Toi Jose A Garcia-Saenz Andreas Hartkopf Daniele Generali Françoise Rothé Jeffrey Smerage Laura Muinelo-Romay Justin Stebbing Patrice Viens Mark Jesus M Magbanua Carolyn S Hall Olav Engebraaten Daisuke Takata José Vidal-Martínez Wendy Onstenk Noriyoshi Fujisawa Eduardo Diaz-Rubio Florin-Andrei Taran Maria Rosa Cappelletti Michail Ignatiadis Charlotte Proudhon Denise M Wolf Jessica B Bauldry Elin Borgen Rin Nagaoka Vicente Carañana Jaco Kraan Marisa Maestro Sara Yvonne Brucker Karsten Weber Fabien Reyal Dominic Amara Mandar G Karhade Randi R Mathiesen Hideaki Tokiniwa Antonio Llombart-Cussac Alessandra Meddis Paul Blanche Koenraad d'Hollander Paul Cottu John W Park Sibylle Loibl Aurélien Latouche Jean-Yves Pierga Klaus Pantel

J Natl Cancer Inst 2018 06;110(6):560-567

Universitätsklinikum Hamburg-Eppendorf, Hamburg, Germany.

View Article and Find Full Text PDF

June 2018

Serum concentrations of active tamoxifen metabolites predict long-term survival in adjuvantly treated breast cancer patients.

Authors:

Thomas Helland Nina Henne Ersilia Bifulco Bjørn Naume Elin Borgen Vessela N Kristensen Jan T Kvaløy Timothy L Lash Grethe I G Alnæs Ron H van Schaik Emiel A M Janssen Steinar Hustad Ernst A Lien Gunnar Mellgren Håvard Søiland

Breast Cancer Res 2017 Nov 28;19(1):125. Epub 2017 Nov 28.

Department of Clinical Science, University of Bergen, Bergen, Norway.

View Article and Find Full Text PDF

November 2017

Prognostic value of PAM50 and risk of recurrence score in patients with early-stage breast cancer with long-term follow-up.

Authors:

Hege O Ohnstad Elin Borgen Ragnhild S Falk Tonje G Lien Marit Aaserud My Anh T Sveli Jon A Kyte Vessela N Kristensen Gry A Geitvik Ellen Schlichting Erik A Wist Therese Sørlie Hege G Russnes Bjørn Naume

Breast Cancer Res 2017 Nov 14;19(1):120. Epub 2017 Nov 14.

Division of Cancer Medicine, Department of Oncology, Oslo University Hospital, Postbox 4953 Nydalen, 0424, Oslo, Norway.

View Article and Find Full Text PDF

November 2017

DNA methylation at enhancers identifies distinct breast cancer lineages.

Authors:

Thomas Fleischer Xavier Tekpli Anthony Mathelier Shixiong Wang Daniel Nebdal Hari P Dhakal Kristine Kleivi Sahlberg Ellen Schlichting Anne-Lise Børresen-Dale Elin Borgen Bjørn Naume Ragnhild Eskeland Arnoldo Frigessi Jörg Tost Antoni Hurtado Vessela N Kristensen

Nat Commun 2017 11 9;8(1):1379. Epub 2017 Nov 9.

Department of Cancer Genetics, Institute for Cancer Research, Oslo University Hospital, The Norwegian Radium Hospital, Oslo, Norway.

View Article and Find Full Text PDF

November 2017

Whole-Genome Sequencing Reveals Breast Cancers with Mismatch Repair Deficiency.

Authors:

Helen Davies Sandro Morganella Colin A Purdie Se Jin Jang Elin Borgen Hege Russnes Dominik Glodzik Xueqing Zou Alain Viari Andrea L Richardson Anne-Lise Børresen-Dale Alastair Thompson Jorunn E Eyfjord Gu Kong Michael R Stratton Serena Nik-Zainal

Cancer Res 2017 09;77(18):4755-4762

Wellcome Trust Sanger Institute, Hinxton, United Kingdom.

View Article and Find Full Text PDF

September 2017

The Longitudinal Transcriptional Response to Neoadjuvant Chemotherapy with and without Bevacizumab in Breast Cancer.

Clin Cancer Res 2017 Aug 9;23(16):4662-4670. Epub 2017 May 9.

Department of Oncology, Oslo University Hospital, Oslo, Norway.

View Article and Find Full Text PDF

August 2017

Survival Impact of Primary Tumor Lymph Node Status and Circulating Tumor Cells in Patients with Colorectal Liver Metastases.

Authors:

Lars Thomas Seeberg Cathrine Brunborg Anne Waage Harald Hugenschmidt Anne Renolen Ingunn Stav Bjørn A Bjørnbeth Elin Borgen Bjørn Naume Kristoffer W Brudvik Gro Wiedswang

Ann Surg Oncol 2017 Aug 3;24(8):2113-2121. Epub 2017 Mar 3.

Department of Gastrointestinal Surgery, Oslo University Hospital, Oslo, Norway.

View Article and Find Full Text PDF

August 2017

Prognostic significance of S100A4-expression and subcellular localization in early-stage breast cancer.

Authors:

Eivind Valen Egeland Kjetil Boye Daehoon Park Marit Synnestvedt Torill Sauer Bjørn Naume Elin Borgen Gunhild M Mælandsmo

Breast Cancer Res Treat 2017 02 5;162(1):127-137. Epub 2017 Jan 5.

Department of Tumor Biology, Institute for Cancer Research, The Norwegian Radium Hospital, Oslo University Hospital, PO Box 4953, 0424, Nydalen, Oslo, Norway.

View Article and Find Full Text PDF

February 2017

Tracing the origin of disseminated tumor cells in breast cancer using single-cell sequencing.

Genome Biol 2016 12 9;17(1):250. Epub 2016 Dec 9.

Department of Oncology, Division of Surgery and Cancer Medicine, Oslo University Hospital, Radiumhospitalet, Oslo, Norway.

View Article and Find Full Text PDF

December 2016

The Sub-Cellular Localization of WRAP53 Has Prognostic Impact in Breast Cancer.

Authors:

Laxmi Silwal-Pandit Hege Russnes Elin Borgen Veronica Skarpeteig Hans Kristian Moen Vollan Ellen Schlichting Rolf Kåresen Bjørn Naume Anne-Lise Børresen-Dale Marianne Farnebo Anita Langerød

PLoS One 2015 13;10(10):e0139965. Epub 2015 Oct 13.

Department of Cancer Genetics, Institute for Cancer Research, Division of Cancer Medicine, Surgery and Transplantation, Radiumhospitalet-Oslo University Hospital, 0424 Oslo, Norway.

View Article and Find Full Text PDF

June 2016

NUT expression in primary lung tumours.

Authors:

Marius Lund-Iversen Krystyna Kotanska Grøholt Åslaug Helland Elin Borgen Odd Terje Brustugun

Diagn Pathol 2015 Sep 5;10:156. Epub 2015 Sep 5.

Department of Oncology, Oslo University Hospital, Radiumhospitalet 0310, Oslo, Norway.

View Article and Find Full Text PDF

September 2015

Detection of Circulating Tumor Cells at Surgery and at Follow-Up Assessment to Predict Survival After Two-Stage Liver Resection of Colorectal Liver Metastases.

Authors:

Kristoffer Watten Brudvik Lars Thomas Seeberg Harald Hugenschmidt Anne Renolen Cecilie Bendigtsen Schirmer Cathrine Brunborg Bjørn Atle Bjørnbeth Elin Borgen Bjørn Naume Anne Waage Gro Wiedswang

Ann Surg Oncol 2015 Nov 24;22(12):4029-37. Epub 2015 Mar 24.

Department of Gastrointestinal Surgery, Oslo University Hospital, Oslo, Norway.

View Article and Find Full Text PDF

November 2015

Clinical outcome with correlation to disseminated tumor cell (DTC) status after DTC-guided secondary adjuvant treatment with docetaxel in early breast cancer.

Authors:

Bjørn Naume Marit Synnestvedt Ragnhild Sørum Falk Gro Wiedswang Kjetil Weyde Terje Risberg Christian Kersten Ingvil Mjaaland Lise Vindi Hilde H Sommer Anna Barbro Sætersdal Maria Christine Rypdal Cecilie Bendigtsen Schirmer Erik Andreas Wist Elin Borgen

J Clin Oncol 2014 Dec 3;32(34):3848-57. Epub 2014 Nov 3.

Bjørn Naume, Marit Synnestvedt, Ragnhild Sørum Falk, Gro Wiedswang, Hilde H. Sommer, Anna Barbro Sætersdal, Maria Christine Rypdal, Cecilie Bendigtsen Schirmer, Erik Andreas Wist, and Elin Borgen, Oslo University Hospital; Bjørn Naume, Erik Andreas Wist, and Elin Borgen, K.G. Jebsen Center for Breast Cancer Research, Institute for Clinical Medicine, University of Oslo, Oslo; Kjetil Weyde, Sykehuset Innlandet Trust, Gjøvik; Terje Risberg, University Hospital of Northern Norway and University of Tromsø, Tromsø; Christian Kersten, Sørlandet Hospital Trust, Kristiansand; Ingvil Mjaaland, Stavanger University Hospital, Stavanger; and Lise Vindi, Ålesund Hospital, Ålesund, Norway.

View Article and Find Full Text PDF

December 2014