Eliezer Van Allen

Eliezer Van Allen

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Eliezer Van Allen

Eliezer Van Allen

Publications by authors named "Eliezer Van Allen"

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Finding the edge of the seat.

Nat Med 2019 09;25(9):1328

Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.

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http://dx.doi.org/10.1038/s41591-019-0557-5DOI Listing
September 2019

Genomic correlates of response to immune checkpoint blockade.

Nat Med 2019 03 6;25(3):389-402. Epub 2019 Mar 6.

Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.

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http://dx.doi.org/10.1038/s41591-019-0382-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6599710PMC
March 2019

Mechanisms of Resistance to Immune Checkpoint Blockade: Why Does Checkpoint Inhibitor Immunotherapy Not Work for All Patients?

Am Soc Clin Oncol Educ Book 2019 Jan 17;39:147-164. Epub 2019 May 17.

5 Division of Hematology and Oncology, Huntsman Cancer Institute, University of Utah, Salt Lake City, UT.

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http://dx.doi.org/10.1200/EDBK_240837DOI Listing
January 2019

Intron retention is a source of neoepitopes in cancer.

Nat Biotechnol 2018 12 16;36(11):1056-1058. Epub 2018 Aug 16.

Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1038/nbt.4239DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6226333PMC
December 2018

Genomics of response to immune checkpoint therapies for cancer: implications for precision medicine.

Genome Med 2018 11 29;10(1):93. Epub 2018 Nov 29.

Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, 02215, USA.

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http://dx.doi.org/10.1186/s13073-018-0605-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6264032PMC
November 2018

Early loss of mitochondrial complex I and rewiring of glutathione metabolism in renal oncocytoma.

Proc Natl Acad Sci U S A 2018 07 18;115(27):E6283-E6290. Epub 2018 Jun 18.

Howard Hughes Medical Institute and Department of Molecular Biology, Massachusetts General Hospital, Boston, MA 02114;

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http://dx.doi.org/10.1073/pnas.1711888115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6142220PMC
July 2018

LSD1 Ablation Stimulates Anti-tumor Immunity and Enables Checkpoint Blockade.

Cell 2018 07 21;174(3):549-563.e19. Epub 2018 Jun 21.

Division of Newborn Medicine and Epigenetics Program, Boston Children's Hospital, Boston, MA 02115, USA; Department of Cell Biology, Harvard Medical School, Boston, MA 02115, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2018.05.052DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6063761PMC
July 2018

Inherited DNA-Repair Defects in Colorectal Cancer.

Am J Hum Genet 2018 03 22;102(3):401-414. Epub 2018 Feb 22.

Department of Medical Oncology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, MA 02215, USA; The Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ajhg.2018.01.018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5985280PMC
March 2018

Profiling of PD-1 Blockade Using Organotypic Tumor Spheroids.

Cancer Discov 2018 02 3;8(2):196-215. Epub 2017 Nov 3.

Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts.

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http://dx.doi.org/10.1158/2159-8290.CD-17-0833DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5809290PMC
February 2018

Tumor Evolution: A Problem of Histocompatibility.

Cell 2017 11;171(6):1252-1253

Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA; Cancer Program, Broad Institute of MIT and Harvard, Cambridge, MA, USA; Center for Cancer Precision Medicine, Dana-Farber Cancer Institute, Boston, MA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2017.11.012DOI Listing
November 2017

The Potential and Challenges of Expanded Germline Testing in Clinical Oncology.

JAMA 2017 09;318(9):801-803

Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts.

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http://dx.doi.org/10.1001/jama.2017.11022DOI Listing
September 2017

Toward Molecularly Driven Precision Medicine in Lung Adenocarcinoma.

Cancer Discov 2017 06;7(6):555-557

Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts.

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http://dx.doi.org/10.1158/2159-8290.CD-17-0355DOI Listing
June 2017

Loss of PTEN Is Associated with Resistance to Anti-PD-1 Checkpoint Blockade Therapy in Metastatic Uterine Leiomyosarcoma.

Immunity 2017 02;46(2):197-204

Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; Center for Cancer Precision Medicine, Dana-Farber Cancer Institute, Boston, MA 02215, USA. Electronic address:

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http://dx.doi.org/10.1016/j.immuni.2017.02.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5408320PMC
February 2017

Genomic Approaches to Understanding Response and Resistance to Immunotherapy.

Clin Cancer Res 2016 Dec 3;22(23):5642-5650. Epub 2016 Oct 3.

Medical Oncology, Dana-Farber Cancer Institute/Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.1158/1078-0432.CCR-16-0066DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5135569PMC
December 2016

Delivering on the promise of precision cancer medicine.

Genome Med 2016 10 25;8(1):110. Epub 2016 Oct 25.

Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, 02215, USA.

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http://dx.doi.org/10.1186/s13073-016-0373-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5078954PMC
October 2016

Genomic determinants of cancer immunotherapy.

Curr Opin Immunol 2016 08 30;41:32-38. Epub 2016 May 30.

Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, United States; Broad Institute of MIT and Harvard, Cambridge, MA 02142, United States; Center for Cancer Precision Medicine, Dana-Farber Cancer Institute, Boston, MA 02215, United States. Electronic address:

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http://dx.doi.org/10.1016/j.coi.2016.05.010DOI Listing
August 2016

Inherited DNA-Repair Gene Mutations in Men with Metastatic Prostate Cancer.

N Engl J Med 2016 Aug 6;375(5):443-53. Epub 2016 Jul 6.

From the University of Washington (C.C.P., M. Beightol, C.M., B.N., H.H.C., B.M., T.W., S. Casadei, P.S.N.) and Fred Hutchinson Cancer Research Center (N.D.S., R.G., P.S.N.) - both in Seattle; the Institute of Cancer Research and Royal Marsden Hospital, London (J.M., S. Carreira, R.E., J.B.); Memorial Sloan Kettering Cancer Center (M.F.W., W.A., M. Berger, L.Z., A.Z., J. Vijai, H.I.S., C.S., N.S., P.W.K., D.S., M.R., K.O.), Weill Cornell Medical College (H.B., O.E., M.A.R.), and the Prostate Cancer Clinical Trials Consortium (J. Vinson, J.F.) - all in New York; the University of Michigan, Ann Arbor (D.R., R.L., M.H., A.C.); Howard Hughes Medical Institute, Chevy Chase, MD (A.C., C.S.); and Dana-Farber Cancer Institute, Boston (A.G., L.G., M.-E.T., S.A., G.C.H., E.M.V.A.).

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http://dx.doi.org/10.1056/NEJMoa1603144DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4986616PMC
August 2016

Genetic Effect of Chemotherapy Exposure in Children of Testicular Cancer Survivors.

Clin Cancer Res 2016 05 2;22(9):2183-9. Epub 2015 Dec 2.

Broad Institute of MIT and Harvard, Cambridge, Massachusetts. Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts.

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http://dx.doi.org/10.1158/1078-0432.CCR-15-2317DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4854770PMC
May 2016

Precision medicine for advanced prostate cancer.

Curr Opin Urol 2016 May;26(3):231-9

aDepartment of Medical Oncology, Dana-Farber Cancer Institute, Boston bCancer Program, Broad Institute of MIT and Harvard, Cambridge cCenter for Cancer Precision Medicine, Dana-Farber Cancer Institute, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1097/MOU.0000000000000278DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4955574PMC
May 2016

Genomic Correlates of Immune-Cell Infiltrates in Colorectal Carcinoma.

Cell Rep 2016 Apr 14;15(4):857-865. Epub 2016 Apr 14.

Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02215, USA; Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2016.03.075DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4850357PMC
April 2016

CSER and eMERGE: current and potential state of the display of genetic information in the electronic health record.

J Am Med Inform Assoc 2015 Nov 3;22(6):1231-42. Epub 2015 Jul 3.

Genome Medicine Institute, Geisinger Medical Center, Danville, PA, USA Department of Medicine, Program for Personalized and Genomic Medicine and Center for Health-Related Informatics and Bioimaging, University of Maryland School of Medicine, Baltimore, MD, USA.

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http://dx.doi.org/10.1093/jamia/ocv065DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5009914PMC
November 2015

Phase 2 trial of sunitinib and gemcitabine in patients with sarcomatoid and/or poor-risk metastatic renal cell carcinoma.

Cancer 2015 Oct 8;121(19):3435-43. Epub 2015 Jun 8.

Kidney Cancer Center, The Lank Center for Genitourinary Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts.

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http://dx.doi.org/10.1002/cncr.29503DOI Listing
October 2015

Next-generation sequencing to guide cancer therapy.

Genome Med 2015 29;7(1):80. Epub 2015 Jul 29.

Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02115 USA ; Broad Institute of MIT and Harvard, Cambridge, MA 02142 USA.

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http://dx.doi.org/10.1186/s13073-015-0203-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4517547PMC
July 2015

Integrative clinical genomics of advanced prostate cancer.

Cell 2015 May;161(5):1215-1228

Michigan Center for Translational Pathology, University of Michigan Medical School, Ann Arbor, MI 48109, USA; Department of Pathology, University of Michigan Medical School, Ann Arbor, MI 48109, USA; Comprehensive Cancer Center, University of Michigan Medical School, Ann Arbor, MI 48109, USA; Department of Urology, University of Michigan Medical School, Ann Arbor, MI 48109, USA; Howard Hughes Medical Institute, University of Michigan, Ann Arbor, MI 48109, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2015.05.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4484602PMC
May 2015