Publications by authors named "Eliška Zazvonilová"

2 Publications

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Multiple occurrence of premature polyarticular osteoarthritis in an early medieval Bohemian cemetery (Prague, Czech Republic).

Int J Paleopathol 2020 09 14;30:35-46. Epub 2020 May 14.

CNRS, UMR 5199 PACEA, Université de Bordeaux, Bât. B8, Allée Geoffroy St Hilaire, CS 50023, 33615 Pessac Cedex, France; Department of Archaeology, Durham University, South Road, Durham, DH1 3LE, United Kingdom. Electronic address:

Objectives: To highlight conditions that may cause early-onset degenerative joint disease, and to assess the possible impact of such diseases upon everyday life.

Material: Four adults aged under 50 years from a medieval skeletal collection of Prague (Czechia).

Methods: Visual, osteometric, X-ray, and histological examinations, stable isotope analysis of bone collagen.

Results: All four individuals showed multiple symmetrical degenerative changes, affecting the majority of joints of the postcranial skeleton. Associated dysplastic deformities were observed in all individuals, including bilateral hip dysplasia (n = 1), flattening of the femoral condyles (n = 3), and substantial deformation of the elbows (n = 3). The diet of the affected individuals differed from the contemporary population sample.

Conclusions: We propose the diagnosis of a mild form of skeletal dysplasia in these four individuals, with multiple epiphyseal dysplasia or type-II collagenopathy linked to premature osteoarthritis as the most probable causes.

Significance: Combining the skeletal findings with information from the medical literature, this paper defines several characteristic traits which may assist with the diagnosis of skeletal dysplasia in the archaeological record.

Limitations: As no genetic analysis was performed to confirm the possible kinship of the individuals, it is not possible to definitively assess whether the individuals suffered from the same hereditary condition or from different forms of skeletal dysplasia.

Suggestions For Further Research: Further studies on premature osteoarthritis in archaeological skeletal series are needed to correct the underrepresentation of these mild forms of dysplasia in past populations.
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September 2020

The impact of using new and conventional methods for the age-at-death estimation in a Czech medieval population (Mikulčice, 9-10 century): the relationship between age-at-death and linear enamel hypoplasia.

Anthropol Anz 2020 Aug;77(3):259-268

Department of Anthropology and Human Genetics, Faculty of Science, Charles University, Viničná 7 - 128 43 Prague 2, Czech Republic.

Recent advances in age-at-death estimation from the skeleton indicate that some of the most commonly used methods based on linear regression provide different results compared to new techniques using Bayesian statistics, and underestimate individuals over 60 years old which leads to biased prehistoric lifespans. The question is how the choice of age-at-death estimation method can influence subsequent comparisons between different populations or further analysis, such as assessment of the effect of early stress on mortality in adult individuals. The aim of our work is twofold: firstly, to test the differences between age estimation methods evaluating one indicator (the auricular surface), namely the original (Lovejoy et al. 1985), revised (Buckberry & Chamberlain 2002) and newly developed (Schmitt 2005) methods, on the Early Medieval adult population from Mikulčice - III church (Czech Republic, Central Europe). The secondary objective is to assess whether the different age distributions based on the different methods have an impact on age-dependent analyses, in this case the relationship between LEH and age-at-death. Our results showed that in the adult population from Mikulčice - III church, the original and revised methods provided different mortality profiles: the proportion of individuals older than 60 years acquired using Lovejoy's method was only 6.7%, while the newer methods increased the proportion to 26.7% (Buckberry & Chamberlain 2002) and 23.9% (Schmitt 2005). The choice of age-at-death estimation, and thus the different age distributions, also resulted in differences in the achieved age of individuals with and without stress markers, and specifically in the significance of the differences found. This finding seeks to draw attention to the fact that inconsistency in the use of different age-estimation methods can influence the results of further analyses and cause problems when comparing burial grounds.
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August 2020