Publications by authors named "Elham Emaratkar"

7 Publications

  • Page 1 of 1

A double-blind, randomized pilot study for comparison of Melissa officinalis L. and Lavandula angustifolia Mill. with Fluoxetine for the treatment of depression.

BMC Complement Med Ther 2020 Jul 3;20(1):207. Epub 2020 Jul 3.

Department of Traditional Medicine, School of Medicine, Shahed University, 1471, North Kargar, Engelab Square, Tehran, Iran.

Background: Depression has rapidly progressed worldwide, and the need for an efficient treatment with low side effect has risen. Melissa officinalis L and Lavandula angustifolia Mill have been traditionally used in Asia for the treatment of depression. Many textbooks of traditional Persian medicine refer to these herbs for the treatment of depression while there are no adequate clinical trials to support this claim. The present study aimed to evaluate the efficacy of M. officinalis and L. angustifolia compared to fluoxetine for the treatment of mild to moderate depression in an 8-week randomized, double-blind clinical trial.

Methods: Forty-five adult outpatients who met the Diagnostic and Statistical Manual of Mental Disorders, 5th edition (DSM-5) for major depression, were randomly assigned to 3 groups to daily receive either M. officinalis (2 g) or L. angustifolia (2 g) or fluoxetine (20 mg) and were assessed in weeks 0, 2, 4 and 8 by the Hamilton Rating Scale for Depression (HAM-D) including 17 items.

Results: Our study showed that M. officinalis and L. angustifolia effect similar to fluoxetine in mild to moderate depression. (F = 0.131, df = 2,42, p = 0.877).

Conclusion: Due to some restrictions in this study including absence of placebo group, large-scale trials are needed to investigate the anti-depressant effect of these two herbs with more details.

Trial Registration: IRCT2014061718126N1 . Registration date: 2015-06-04-"Retrospectively registered".
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http://dx.doi.org/10.1186/s12906-020-03003-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7333290PMC
July 2020

Effect of (Lemon balm) on Sexual Dysfunction in Women: A Double- blind, Randomized, Placebo-controlled Study.

Iran J Pharm Res 2018 ;17(Suppl):89-100

Department of Obstetrics and Gynecology Medical Science, Shahed University, Tehran, Iran.

Hypoactive sexual desire disorder (HSDD) is the most prevalent female sexual dysfunction (FSD) and its bio-psychosocial multifactorial etiology justifies its multifaceted treatment. In Persian Medicine (PM), the weakness of the main organs (heart, brain and liver) is one of the important causes of lack of sexual desire; hence, their strengthening is a priority during treatment. is one of the medicinal plants with tonic characteristics for the main organs in PM and was used for treatment in this study. The aim of the present study was to evaluate the efficacy and safety of in the improvement of HSDD in women. Eighty nine (89) eligible women suffering from decreased sexual desire were randomly assigned to groups. The participants received medication (500 mg of aqueous extract of ) or placebo 2 times a day for 4 weeks. Changes in scores of desire, arousal, lubrication, orgasm, satisfaction and pain were evaluated at the end of 4 weeks of treatment using the Female Sexual Function Index (FSFI) questionnaire in the two groups. Forty three participants completed the study. The increase in desire ( < 0.001), arousal ( < 0.001), lubrication ( < 0.005), orgasm ( < 0.001), satisfaction ( < 0.001), pain ( < 0.002) and FSFI total score ( < 0.001) in the M. officinalis group was significantly more than that of the placebo group. The willingness to continue treatment was significantly higher in the M. officinalis as compared to the placebo group ( < 0.001). M. officinalis may be a safe and effective herbal medicine for the improvement of HSDD in women.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5958328PMC
January 2018

Effect of Benth. on allergic rhinitis symptoms: A randomized double-blind clinical trial.

J Res Med Sci 2017 28;22:128. Epub 2017 Nov 28.

Traditional Medicine Clinical Trial Research Center, Shahed University, Tehran, Iran.

Background: Allergic rhinitis (AR) is one of the health problems in the world. It is necessary to develop new treatment procedure for control of this disease. The aim of this study was to assess the effect of ( Benth) on AR patients.

Materials And Methods: In this double-blind randomized clinical trial study, 71 patients (37 patients in treatment and 34 in placebo group) participated. In treatment group, syrup (NBS) was used for 4 weeks as three times a day. The efficacy of the drug regarding AR symptoms (rhinorrhea, sneezing, nasal obstruction, itchy nose, and ocular symptoms) were evaluated through a visual analog scale (VAS) by 0-10 before administration and at the end of the whole treatment period. The collected information was entered in the SPSS software (version 18) and was analyzed using the Fisher's exact test, Chi-square test, independent sample -test, and paired sample test.

Results: The improvement of AR symptoms in the group receiving NBS was significantly higher compared to control group (4.73 ± 1.84 vs. 0.38 ± 2.06; < 0.0001). Furthermore, the mean of total VAS before and after the treatment (in case group) was 7.10 ± 1.92 and 2.37 ± 1.76, respectively ( < 0.001).

Conclusion: The results of this study indicate that has significant effects on improving the symptoms of AR. Hence, it can be a good alternative to AR symptoms relief.
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http://dx.doi.org/10.4103/jrms.JRMS_316_17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5721487PMC
November 2017

Persian Traditional Medicine and Ocular Health.

Med Hypothesis Discov Innov Ophthalmol 2015 ;4(4):162-166

Department of Traditional Medicine, School of Medicine, Shahed University, Tehran, Iran.

The Persian Traditional Medicine (PTM) system pays special attention to disease prevention. In PTM, physicians believe that overeating may cause accumulation of unhealthy substances in the body and diseases called "Emtela." With respect to ocular health, foods can be categorized as beneficial and harmful. Harmful foods such as beef, geese, eggplant, cauliflower, and cheese can cause reduced vision. Dehydrating foods such as walnut and salty fish and hot foods such as garlic, onion, and pepper can cause dry eye. Food items that have beneficial effects on ocular health include thyme and saffron and fruits such as grape, fig, apple, plum, and berries. PTM stipulates that one should not drink water with meals or immediately afterwards, since drinking cold (icy) water causes difficulty in absorption of nutrients. Gulping water may have harmful effects on the eyes; therefore, PTM physicians recommend drinking water at a suitable temperature. It is not safe to drink water first at the morning. Sleeping right after eating is harmful too. Avicenna believes that sleeping on one's belly after a full meal is very harmful for the eyes. Galen says that old people need deep and continuous sleep more than others. From the view of PTM, moving eyes in different directions, making delicate expressions, trying to look at delicate and find pictures and reading small letters would remove ocular fatigue. There have been mentions of local medicine for improving vision as well; for instance, fennel extracts, pomegranate juice, and honey which are suitable for vision improvement. Local administration of pomegranate blossoms is suitable for treating inflammatory reactions.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5087098PMC
January 2015

Avicenna's view on the prevention of thrombosis.

Int J Cardiol 2013 Oct 3;168(3):3093-4. Epub 2013 May 3.

Department of Traditional Medicine, School of Medicine, Shahed University, Tehran, Iran.

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http://dx.doi.org/10.1016/j.ijcard.2013.04.079DOI Listing
October 2013

Avicenna's view on the prevention of thrombosis.

Int J Cardiol 2013 Jun 9;166(1):274-5. Epub 2012 Nov 9.

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http://dx.doi.org/10.1016/j.ijcard.2012.09.151DOI Listing
June 2013