Publications Authored by Eleonora Franzè

Induction of endoplasmic reticulum stress and inhibition of colon carcinogenesis by the anti-helmintic drug rafoxanide.

Authors:

Federica Laudisi Antonio Di Grazia Veronica De Simone Fabio Cherubini Alfredo Colantoni Angela Ortenzi Eleonora Franzè Vincenzo Dinallo Davide Di Fusco Ivan Monteleone Eric R Fearon Giovanni Monteleone Carmine Stolfi

Cancer Lett 2019 Oct 24;462:1-11. Epub 2019 Jul 24.

Department of Systems Medicine, University of "Tor Vergata", Rome, Italy. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S03043835193041	Publisher Site
http://dx.doi.org/10.1016/j.canlet.2019.07.014	DOI Listing

October 2019

Progranulin sustains STAT3 hyper-activation and oncogenic function in colorectal cancer cells.

Authors:

Federica Laudisi Fabio Cherubini Antonio Di Grazia Vincenzo Dinallo Davide Di Fusco Eleonora Franzè Angela Ortenzi Illari Salvatori Silvia Scaricamazza Ivan Monteleone Naoya Sakamoto Giovanni Monteleone Carmine Stolfi

Mol Oncol 2019 Oct 10;13(10):2142-2159. Epub 2019 Aug 10.

Department of Systems Medicine, University of 'Tor Vergata', Rome, Italy.

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http://dx.doi.org/10.1002/1878-0261.12552	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6763778	PMC

October 2019

Reciprocal Regulation Between Smad7 and Sirt1 in the Gut.

Authors:

Silvia Sedda Eleonora Franzè Gerolamo Bevivino Martina Di Giovangiulio Angelamaria Rizzo Alfredo Colantoni Angela Ortenzi Enrico Grasso Mario Giannelli Giuseppe S Sica Massimo Claudio Fantini Giovanni Monteleone

Front Immunol 2018 10;9:1854. Epub 2018 Aug 10.

Department of Systems Medicine, University of Rome Tor Vergata, Rome, Italy.

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http://dx.doi.org/10.3389/fimmu.2018.01854	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6097015	PMC

September 2019

Tbet Expression in Regulatory T Cells Is Required to Initiate Th1-Mediated Colitis.

Authors:

Martina Di Giovangiulio Angelamaria Rizzo Eleonora Franzè Flavio Caprioli Federica Facciotti Sara Onali Agnese Favale Carmine Stolfi Hans-Joerg Fehling Giovanni Monteleone Massimo C Fantini

Front Immunol 2019 11;10:2158. Epub 2019 Sep 11.

Department of Systems Medicine, University of Rome "Tor Vergata", Rome, Italy.

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http://dx.doi.org/10.3389/fimmu.2019.02158	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6749075	PMC

September 2019

Cadherin-11 is a Regulator of Intestinal Fibrosis.

Authors:

Eleonora Franzè Ivan Monteleone Federica Laudisi Angelamaria Rizzo Vincenzo Dinallo Davide Di Fusco Alfredo Colantoni Angela Ortenzi Paolo Giuffrida Sara Di Carlo Giuseppe S Sica Antonio Di Sabatino Giovanni Monteleone

J Crohns Colitis 2019 Aug 23. Epub 2019 Aug 23.

Department of Systems Medicine, University of Rome "TOR VERGATA ", Rome, Italy.

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http://dx.doi.org/10.1093/ecco-jcc/jjz147	DOI Listing

August 2019

Neutrophil Extracellular Traps Sustain Inflammatory Signals in Ulcerative Colitis.

Authors:

Vincenzo Dinallo Irene Marafini Davide Di Fusco Federica Laudisi Eleonora Franzè Antonio Di Grazia Michele M Figliuzzi Flavio Caprioli Carmine Stolfi Ivan Monteleone Giovanni Monteleone

J Crohns Colitis 2019 May;13(6):772-784

Department of Systems Medicine, University of 'Tor Vergata', Rome, Italy.

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http://dx.doi.org/10.1093/ecco-jcc/jjy215	DOI Listing

May 2019

NPD-0414-2 and NPD-0414-24, Two Chemical Entities Designed as Aryl Hydrocarbon Receptor (AhR) Ligands, Inhibit Gut Inflammatory Signals.

Authors:

Irene Marafini Davide Di Fusco Vincenzo Dinallo Eleonora Franzè Carmine Stolfi Giuseppe Sica Giovanni Monteleone Ivan Monteleone

Front Pharmacol 2019 12;10:380. Epub 2019 Apr 12.

Department of Biomedicine and Prevention, University of Tor Vergata, Rome, Italy.

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http://dx.doi.org/10.3389/fphar.2019.00380	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6473199	PMC

April 2019

RORγt-Expressing Tregs Drive the Growth of Colitis-Associated Colorectal Cancer by Controlling IL6 in Dendritic Cells.

Authors:

Angelamaria Rizzo Martina Di Giovangiulio Carmine Stolfi Eleonora Franzè Hans-Joerg Fehling Rita Carsetti Ezio Giorda Alfredo Colantoni Angela Ortenzi Massimo Rugge Claudia Mescoli Giovanni Monteleone Massimo C Fantini

Cancer Immunol Res 2018 09 10;6(9):1082-1092. Epub 2018 Jul 10.

Department of System Medicine, University of Rome Tor Vergata, Rome, Italy.

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http://dx.doi.org/10.1158/2326-6066.CIR-17-0698	DOI Listing

September 2018

Follistatin-like protein 1 sustains colon cancer cell growth and survival.

Authors:

Gerolamo Bevivino Silvia Sedda Eleonora Franzè Carmine Stolfi Antonio Di Grazia Vincenzo Dinallo Flavio Caprioli Federica Facciotti Alfredo Colantoni Angela Ortenzi Piero Rossi Giovanni Monteleone

Oncotarget 2018 Jul 27;9(58):31278-31290. Epub 2018 Jul 27.

Department of Systems Medicine, University of Tor Vergata, Rome, Italy.

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http://dx.doi.org/10.18632/oncotarget.25811	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6101290	PMC

July 2018

Metformin inhibits inflammatory signals in the gut by controlling AMPK and p38 MAP kinase activation.

Authors:

Davide Di Fusco Vincenzo Dinallo Ivan Monteleone Federica Laudisi Irene Marafini Eleonora Franzè Antonio Di Grazia Rami Dwairi Alfredo Colantoni Angela Ortenzi Carmine Stolfi Giovanni Monteleone

Clin Sci (Lond) 2018 06 12;132(11):1155-1168. Epub 2018 Jun 12.

Department of Systems Medicine, University of "Tor Vergata", Rome, Italy

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http://clinsci.org/lookup/doi/10.1042/CS20180167	Publisher Site
http://dx.doi.org/10.1042/CS20180167	DOI Listing

June 2018

Knockdown of Smad7 With a Specific Antisense Oligonucleotide Attenuates Colitis and Colitis-Driven Colonic Fibrosis in Mice.

Authors:

Roberta Izzo Gerolamo Bevivino Veronica De Simone Silvia Sedda Ivan Monteleone Irene Marafini Martina Di Giovangiulio Angelamaria Rizzo Eleonora Franzè Alfredo Colantoni Angela Ortenzi Giovanni Monteleone

Inflamm Bowel Dis 2018 05;24(6):1213-1224

Dipartimento di Medicina dei Sistemi, Università Tor Vergata, Rome, Italy.

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http://dx.doi.org/10.1093/ibd/izy062	DOI Listing

May 2018

Interleukin-34 sustains pro-tumorigenic signals in colon cancer tissue.

Authors:

Eleonora Franzè Vicenzo Dinallo Angela Rizzo Martina Di Giovangiulio Gerolamo Bevivino Carmine Stolfi Flavio Caprioli Alfredo Colantoni Angela Ortenzi Antonio Di Grazia Giuseppe Sica Pier Paolo Sileri Piero Rossi Giovanni Monteleone

Oncotarget 2018 01 15;9(3):3432-3445. Epub 2017 Dec 15.

Department of Systems Medicine, University of Rome "TOR VERGATA", Rome, Italy.

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http://dx.doi.org/10.18632/oncotarget.23289	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5790474	PMC

January 2018

Smad7 knockdown activates protein kinase RNA-associated eIF2α pathway leading to colon cancer cell death.

Authors:

Veronica De Simone Gerolamo Bevivino Silvia Sedda Roberta Izzo Federica Laudisi Vincenzo Dinallo Eleonora Franzè Alfredo Colantoni Angela Ortenzi Silvia Salvatori Piero Rossi Giuseppe S Sica Massimo C Fantini Carmine Stolfi Giovanni Monteleone

Cell Death Dis 2017 03 16;8(3):e2681. Epub 2017 Mar 16.

Department of Systems Medicine, University of 'Tor Vergata', Rome, Italy.

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http://dx.doi.org/10.1038/cddis.2017.103	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5386514	PMC

March 2017

Aryl hydrocarbon receptor-driven signals inhibit collagen synthesis in the gut.

Authors:

Ivan Monteleone Francesca Zorzi Irene Marafini Davide Di Fusco Vincenzo Dinallo Roberta Caruso Roberta Izzo Eleonora Franzè Alfredo Colantoni Francesco Pallone Giovanni Monteleone

Eur J Immunol 2016 Apr 5;46(4):1047-57. Epub 2016 Feb 5.

Dipartimento di Medicina dei Sistemi, Università Tor Vergata, Rome, Italy.

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http://dx.doi.org/10.1002/eji.201445228	DOI Listing

April 2016

Interleukin-34 Induces Cc-chemokine Ligand 20 in Gut Epithelial Cells.

Authors:

Eleonora Franzè Irene Marafini Veronica De Simone Ivan Monteleone Flavio Caprioli Alfredo Colantoni Angela Ortenzi Francesca Crescenzi Roberta Izzo Giuseppe Sica PierPaolo Sileri Piero Rossi Francesco Pallone Giovanni Monteleone

J Crohns Colitis 2016 Jan 8;10(1):87-94. Epub 2015 Oct 8.

Department of Systems Medicine, University of Rome 'TOR VERGATA', Rome, Italy

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http://dx.doi.org/10.1093/ecco-jcc/jjv181	DOI Listing

January 2016

Defective expression of scavenger receptors in celiac disease mucosa.

Authors:

Maria Laura Cupi Massimiliano Sarra Daniela De Nitto Eleonora Franzè Irene Marafini Ivan Monteleone Giovanna Del Vecchio Blanco Omero Alessandro Paoluzi Davide Di Fusco Paolo Gentileschi Angela Ortenzi Alfredo Colantoni Francesco Pallone Giovanni Monteleone

PLoS One 2014 27;9(6):e100980. Epub 2014 Jun 27.

Dipartimento di Medicina dei Sistemi, Università Tor Vergata, Rome, Italy.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0100980	PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4074117	PMC

October 2015

Interleukin-34 sustains inflammatory pathways in the gut.

Authors:

Eleonora Franzè Ivan Monteleone Maria Laura Cupi Pamela Mancia Flavio Caprioli Irene Marafini Alfredo Colantoni Angela Ortenzi Federica Laudisi Giuseppe Sica PierPaolo Sileri Francesco Pallone Giovanni Monteleone

Clin Sci (Lond) 2015 Aug;129(3):271-80

*Department of Systems Medicine, University of Rome "Tor Vergata", Via Montpellier 1, 00133 Rome, Italy.

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http://dx.doi.org/10.1042/CS20150132	DOI Listing

August 2015

Interleukin-21 sustains inflammatory signals that contribute to sporadic colon tumorigenesis.

Authors:

Veronica De Simone Giulia Ronchetti Eleonora Franzè Alfredo Colantoni Angela Ortenzi Massimo C Fantini Angelamaria Rizzo Giuseppe S Sica Pierpaolo Sileri Piero Rossi Thomas T MacDonald Francesco Pallone Giovanni Monteleone Carmine Stolfi

Oncotarget 2015 Apr;6(12):9908-23

Department of Systems Medicine, University of Rome "Tor Vergata", Rome, Italy.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4496406	PMC
http://dx.doi.org/10.18632/oncotarget.3532	DOI Listing

April 2015

Plasma cells in the mucosa of patients with inflammatory bowel disease produce granzyme B and possess cytotoxic activities.

Authors:

Maria Laura Cupi Massimiliano Sarra Irene Marafini Ivan Monteleone Eleonora Franzè Angela Ortenzi Alfredo Colantoni Giuseppe Sica Pierpaolo Sileri M Manuela Rosado Rita Carsetti Thomas T MacDonald Francesco Pallone Giovanni Monteleone

J Immunol 2014 Jun 16;192(12):6083-91. Epub 2014 May 16.

Department of Systems Medicine, University of Rome "Tor Vergata," 00133 Rome, Italy;

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http://dx.doi.org/10.4049/jimmunol.1302238	DOI Listing

June 2014

Lesional accumulation of CD163-expressing cells in the gut of patients with inflammatory bowel disease.

Authors:

Eleonora Franzè Roberta Caruso Carmine Stolfi Massimiliano Sarra Maria Laura Cupi Flavio Caprioli Ivan Monteleone Francesca Zorzi Daniela De Nitto Alfredo Colantoni Livia Biancone Francesco Pallone Giovanni Monteleone

PLoS One 2013 26;8(7):e69839. Epub 2013 Jul 26.

Department of Systems Medicine, University TOR VERGATA of Rome, Rome, Italy.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0069839	PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3724902	PMC

April 2014

IL-25 prevents and cures fulminant hepatitis in mice through a myeloid-derived suppressor cell-dependent mechanism.

Authors:

Massimiliano Sarra Maria Laura Cupi Roberta Bernardini Giulia Ronchetti Ivan Monteleone Marco Ranalli Eleonora Franzè Angelamaria Rizzo Alfredo Colantoni Flavio Caprioli Marco Maggioni Alessandra Gambacurta Maurizio Mattei Thomas T Macdonald Francesco Pallone Giovanni Monteleone

Hepatology 2013 Oct 26;58(4):1436-50. Epub 2013 Aug 26.

Department of Systems Medicine, University of Rome "Tor Vergata", Rome, Italy.

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http://dx.doi.org/10.1002/hep.26446	DOI Listing

October 2013

High expression of the "A Disintegrin And Metalloprotease" 19 (ADAM19), a sheddase for TNF-α in the mucosa of patients with inflammatory bowel diseases.

Authors:

Eleonora Franzè Roberta Caruso Carmine Stolfi Massimiliano Sarra Maria Laura Cupi Marta Ascolani Silvia Sedda Claudia Antenucci Alessandra Ruffa Flavio Caprioli Thomas T MacDonald Francesco Pallone Giovanni Monteleone

Inflamm Bowel Dis 2013 Mar;19(3):501-11

Department of Internal Medicine, University of Rome Tor Vergata, Rome, Italy.

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https://academic.oup.com/ibdjournal/article/19/3/501-511/460	Publisher Site
http://dx.doi.org/10.1097/MIB.0b013e31828028e8	DOI Listing

March 2013

Tissue inhibitor of metalloproteinase-3 regulates inflammation in human and mouse intestine.

Authors:

Ivan Monteleone Massimo Federici Massimiliano Sarra Eleonora Franzè Viviana Casagrande Francesca Zorzi Michele Cavalera Angelamaria Rizzo Renato Lauro Francesco Pallone Thomas T MacDonald Giovanni Monteleone

Gastroenterology 2012 Nov 20;143(5):1277-1287.e4. Epub 2012 Jul 20.

Dipartimento di Medicina dei Sistemi, Università Tor Vergata, Rome, Italy. Electronic address:

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http://dx.doi.org/10.1053/j.gastro.2012.07.016	DOI Listing

November 2012

2-Methoxy-5-amino-N-hydroxybenzamide, a derivative of mesalamine, inhibits colon cancer cell growth through cyclo-oxygenase-2-dependent and -independent mechanisms.

Authors:

Carmine Stolfi Eleonora Franzè Ivan Monteleone Roberta Caruso Luana Franceschilli Pierpaolo Sileri Giuseppe S Sica Achille L Gaspari Giovanna Del Vecchio Blanco Francesco Pallone Giovanni Monteleone

Clin Sci (Lond) 2012 Sep;123(5):295-306

Department of Internal Medicine, University of Rome 'Tor Vergata', Rome, Italy.

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http://dx.doi.org/10.1042/CS20110556	DOI Listing

September 2012

Inhibition of colitis by IL-25 associates with induction of alternatively activated macrophages.

Authors:

Angelamaria Rizzo Ivan Monteleone Daniele Fina Carmine Stolfi Roberta Caruso Massimo Claudio Fantini Eleonora Franzè Reto Schwendener Francesco Pallone Giovanni Monteleone

Inflamm Bowel Dis 2012 Mar 17;18(3):449-59. Epub 2011 Jun 17.

Department of Internal Medicine, University Tor Vergata of Rome, Rome, Italy.

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http://dx.doi.org/10.1002/ibd.21799	DOI Listing

March 2012

2-methoxy-5-amino-N-hydroxybenzamide sensitizes colon cancer cells to TRAIL-induced apoptosis by regulating death receptor 5 and survivin expression.

Authors:

Carmine Stolfi Roberta Caruso Eleonora Franzè Angelamaria Rizzo Angela Rotondi Ivan Monteleone Massimo Claudio Fantini Francesco Pallone Giovanni Monteleone

Mol Cancer Ther 2011 Oct 4;10(10):1969-81. Epub 2011 Aug 4.

Department of Internal Medicine, Università Tor Vergata, Via Montpellier, 1-00133, Rome, Italy.

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http://dx.doi.org/10.1158/1535-7163.MCT-11-0316	DOI Listing

October 2011

Involvement of interleukin-21 in the regulation of colitis-associated colon cancer.

Authors:

Carmine Stolfi Angelamaria Rizzo Eleonora Franzè Angela Rotondi Massimo Claudio Fantini Massimiliano Sarra Roberta Caruso Ivan Monteleone Pierpaolo Sileri Luana Franceschilli Flavio Caprioli Stefano Ferrero Thomas T MacDonald Francesco Pallone Giovanni Monteleone

J Exp Med 2011 Oct 10;208(11):2279-90. Epub 2011 Oct 10.

Gastroenterology Unit, Department of Internal Medicine, University of Rome Tor Vergata, Rome, Italy.

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http://jem.rupress.org/content/208/11/2279.full.pdf	Web Search
http://www.jem.org/lookup/doi/10.1084/jem.20111106	Publisher Site
http://dx.doi.org/10.1084/jem.20111106	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3201207	PMC