Eleni Efstathiou

Eleni Efstathiou

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Eleni Efstathiou

Eleni Efstathiou

Publications by authors named "Eleni Efstathiou"

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Prostate Cancer: Quo Vadis?

Eur Urol 2019 Dec 9;76(6):709-711. Epub 2019 Jul 9.

Genitourinary Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.

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http://dx.doi.org/10.1016/j.eururo.2019.06.031DOI Listing
December 2019

Systemic Treatment of Prostate Cancer in Elderly Patients: Current Role and Safety Considerations of Androgen-Targeting Strategies.

Drugs Aging 2019 08;36(8):701-717

Department of Genitourinary Medical Oncology, The University of Texas MD Anderson Cancer Center, 1155 Pressler Street, Houston, TX, 77030, USA.

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http://dx.doi.org/10.1007/s40266-019-00677-6DOI Listing
August 2019

Enzalutamide in Combination with Abiraterone Acetate in Bone Metastatic Castration-resistant Prostate Cancer Patients.

Eur Urol Oncol 2019 Apr 19. Epub 2019 Apr 19.

Department of Genitourinary Medical Oncology, Stanford Alexander Tissue Derivatives Laboratory, David H. Koch Center for Applied Research of Genitourinary Cancers, Houston, TX, USA.

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http://dx.doi.org/10.1016/j.euo.2019.01.008DOI Listing
April 2019

Attaining precision therapy in prostate cancer: A tall order.

Authors:
Eleni Efstathiou

Eur J Cancer 2017 08 16;81:226-227. Epub 2017 Jun 16.

The University of Texas MD Anderson Cancer Center, Dept of Genitourinary Medical Oncology, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S09598049173096
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http://dx.doi.org/10.1016/j.ejca.2017.05.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6051349PMC
August 2017

Targeting of CYP17A1 Lyase by VT-464 Inhibits Adrenal and Intratumoral Androgen Biosynthesis and Tumor Growth of Castration Resistant Prostate Cancer.

Sci Rep 2016 10 17;6:35354. Epub 2016 Oct 17.

Department of Genitourinary Medical Oncology, David H. Koch Center for Applied Research of Genitourinary Cancers, The University of Texas MD Anderson Cancer Center, Houston, Texas.

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http://dx.doi.org/10.1038/srep35354DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5066251PMC
October 2016

Expression of α5-integrin, α7-integrin, Ε-cadherin, and N-cadherin in localized prostate cancer.

Urol Oncol 2016 Apr 2;34(4):165.e11-8. Epub 2015 Dec 2.

Department of Clinical Therapeutics, School of Medicine, Alexandra Hospital, University of Athens, Athens, Greece.

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http://dx.doi.org/10.1016/j.urolonc.2015.10.016DOI Listing
April 2016

Integrating Murine and Clinical Trials with Cabozantinib to Understand Roles of MET and VEGFR2 as Targets for Growth Inhibition of Prostate Cancer.

Clin Cancer Res 2016 Jan 13;22(1):107-21. Epub 2015 Aug 13.

Department of Genitourinary Medical Oncology, David H. Koch Center for Applied Research of Genitourinary Cancers, The University of Texas MD Anderson Cancer Center, Houston, Texas. Programs in Cancer Biology and Cancer Metastasis, The University of Texas Graduate School of Biomedical Sciences at Houston, Houston, Texas.

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http://dx.doi.org/10.1158/1078-0432.CCR-15-0235DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4703437PMC
January 2016

Long-term Safety and Antitumor Activity in the Phase 1-2 Study of Enzalutamide in Pre- and Post-docetaxel Castration-Resistant Prostate Cancer.

Eur Urol 2015 Nov 16;68(5):795-801. Epub 2015 Feb 16.

Genitourinary Oncology Service, Department of Medicine, Sidney Kimmel Center for Prostate and Urologic Cancers, Memorial Sloan-Kettering Cancer Center, Department of Medicine, Weill Cornell Medical College, New York, NY, USA.

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http://dx.doi.org/10.1016/j.eururo.2015.01.026DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5013546PMC
November 2015

Metastatic Prostate Cancer and the Bone: Significance and Therapeutic Options.

Eur Urol 2015 Nov 4;68(5):850-8. Epub 2015 Jul 4.

Centre Hospitalier de I'Université de Montréal, Montreal, Quebec, Canada.

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http://dx.doi.org/10.1016/j.eururo.2015.06.039DOI Listing
November 2015

PRUNE2 is a human prostate cancer suppressor regulated by the intronic long noncoding RNA PCA3.

Proc Natl Acad Sci U S A 2015 Jul 15;112(27):8403-8. Epub 2015 Jun 15.

David H. Koch Center for Applied Research of Genitourinary Cancers, The University of Texas M.D. Anderson Cancer Center, Houston, TX 77030; University of New Mexico Cancer Center, University of New Mexico School of Medicine, Albuquerque, NM 87131; Department of Internal Medicine, University of New Mexico School of Medicine, Albuquerque, NM 87131; Department of Genitourinary Medical Oncology, The University of Texas M.D. Anderson Cancer Center, Houston, TX 77030; Division of Hematology/Oncology, University of New Mexico School of Medicine, Albuquerque, NM 87131;

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http://dx.doi.org/10.1073/pnas.1507882112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4500257PMC
July 2015

Phase III, randomized, double-blind, multicenter trial comparing orteronel (TAK-700) plus prednisone with placebo plus prednisone in patients with metastatic castration-resistant prostate cancer that has progressed during or after docetaxel-based therapy: ELM-PC 5.

J Clin Oncol 2015 Mar 26;33(7):723-31. Epub 2015 Jan 26.

Karim Fizazi, Institut Gustave Roussy, University of Paris Sud, Villejuif; Stephane Oudard, Université Paris Descartes, Paris, France; Robert Jones, Institute of Cancer Sciences, University of Glasgow, Glasgow; Johann De Bono, The Institute of Cancer Research, London, United Kingdom; Eleni Efstathiou, University of Athens Medical School, Athens; George Fountzilas, Aristotle University of Thessaloniki School of Medicine, Thessaloniki, Greece; Fred Saad, University of Montreal Hospital Center, Montreal, Canada; Ronald de Wit, Erasmus University Medical Center, Rotterdam, the Netherlands; Felipe Melo Cruz, ABC Foundation School of Medicine, Santo André; Flavio Carcano, Hospital de Cancer de Barretos, Barretos, Brazil; Albertas Ulys, Institut of Oncology, Vilnius University, Vilnius, Lithuania; Neeraj Agarwal, Huntsman Cancer Institute, University of Utah, Salt Lake City, UT; David Agus, University of Southern California, Los Angeles, CA; Daniel P. Petrylak, Yale University Cancer Center, New Haven, CT; Shih-Yuan Lee, Bindu Tejura, Niels Borgstein, Takeda Pharmaceuticals International; Iain J. Webb, Millennium: The Takeda Oncology Company, Cambridge, MA; Robert Dreicer, Cleveland Clinic, Cleveland, OH; Joaquim Bellmunt, University Hospital del Mar-IMIM, Barcelona, Spain.

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http://ascopubs.org/doi/10.1200/JCO.2014.56.5119
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http://dx.doi.org/10.1200/JCO.2014.56.5119DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4879718PMC
March 2015

Molecular characterization of enzalutamide-treated bone metastatic castration-resistant prostate cancer.

Eur Urol 2015 Jan 29;67(1):53-60. Epub 2014 May 29.

Department of Genitourinary Medical Oncology, Stanford Alexander Tissue Derivatives Laboratory, David H. Koch Center for Applied Research of Genitourinary Cancers, Houston, TX, USA. Electronic address:

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http://dx.doi.org/10.1016/j.eururo.2014.05.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4247811PMC
January 2015

Glucocorticoid receptor confers resistance to antiandrogens by bypassing androgen receptor blockade.

Cell 2013 Dec;155(6):1309-22

Human Oncology and Pathogenesis Program, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA; Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA.

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http://dx.doi.org/10.1016/j.cell.2013.11.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3932525PMC
December 2013

Molecular classification of prostate cancer progression: foundation for marker-driven treatment of prostate cancer.

Cancer Discov 2013 Aug 28;3(8):849-61. Epub 2013 Jun 28.

Departments of 1Genitourinary Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.

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http://dx.doi.org/10.1158/2159-8290.CD-12-0460DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3926428PMC
August 2013

Clinically atypical seminomas with yolk sac tumor features.

Can J Urol 2013 Aug;20(4):6860-7

Department of Genitourinary Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030-3721, USA.

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August 2013

Bartonella quintana endocarditis as a cause of severe aortic insufficiency and heart failure.

Hellenic J Cardiol 2012 Nov-Dec;53(6):476-9

Department of Clinical Therapeutics, Alexandra Hospital, University of Athens, Greece.

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July 2013

Androgen deprivation therapy and cardiovascular risk.

Nephrourol Mon 2013 15;5(1):653-4. Epub 2012 Dec 15.

Department of Urology, School of Medicine, University of Athens, Sismanoglio General Hospital, Athens, Greece.

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http://dx.doi.org/10.5812/numonthly.7597DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3614327PMC
April 2013

Recurrent seminomas: clinical features and biologic implications.

Urol Oncol 2012 Jul-Aug;30(4):494-501. Epub 2010 Sep 6.

Department of Genitourinary Medical Oncology, The University of Texas M. D. Anderson Cancer Center, Houston, TX 77030, USA.

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http://dx.doi.org/10.1016/j.urolonc.2010.05.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3856193PMC
November 2012

Hedgehog signaling inhibition by the small molecule smoothened inhibitor GDC-0449 in the bone forming prostate cancer xenograft MDA PCa 118b.

Prostate 2012 Nov 27;72(15):1638-47. Epub 2012 Mar 27.

Department of Genitourinary Medical Oncology, The David Koch Center for Applied Research of Genitourinary Cancers, The Stanford Alexander Tissue Derivatives Laboratory, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030-4009, USA.

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http://dx.doi.org/10.1002/pros.22517DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4977841PMC
November 2012

Modeling a lethal prostate cancer variant with small-cell carcinoma features.

Clin Cancer Res 2012 Feb 12;18(3):666-77. Epub 2011 Dec 12.

Department of Genitourinary Medical Oncology, Stanford Alexander Tissue Derivatives Laboratory, David H. Koch Center for Applied Research of Genitourinary Cancers, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA.

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http://clincancerres.aacrjournals.org/cgi/doi/10.1158/1078-0
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http://dx.doi.org/10.1158/1078-0432.CCR-11-1867DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3923417PMC
February 2012

Activation of β-catenin signaling in androgen receptor-negative prostate cancer cells.

Clin Cancer Res 2012 Feb;18(3):726-36

Department of Genitourinary Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA.

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http://dx.doi.org/10.1158/1078-0432.CCR-11-2521DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3271798PMC
February 2012

The role of the cell adhesion molecules (integrins/cadherins) in prostate cancer.

Int Braz J Urol 2011 May-Jun;37(3):302-6

2nd Department of Urology, School of Medicine, University of Athens, Sismanoglio Hospital, Athens, Greece.

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http://dx.doi.org/10.1590/s1677-55382011000300002DOI Listing
December 2011

The novel prostate cancer antigen 3 (PCA3) biomarker.

Int Braz J Urol 2010 Nov-Dec;36(6):665-8; discussion 669

University Department of Urology, Sismanoglio Hospital, Athens, Greece.

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http://dx.doi.org/10.1590/s1677-55382010000600003DOI Listing
September 2011

Abiraterone acetate.

Nat Rev Drug Discov 2011 Aug 1;10(8):573-4. Epub 2011 Aug 1.

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http://dx.doi.org/10.1038/nrd3516DOI Listing
August 2011

Therapeutic targeting of the prostate cancer microenvironment.

Nat Rev Urol 2010 Sep;7(9):494-509

Department of Genitourinary Medical Oncology, David H. Koch Center for Applied Research of Genitourinary Cancers, The University of Texas M. D. Anderson Cancer Center, Houston, TX 77230-1439, USA.

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http://dx.doi.org/10.1038/nrurol.2010.134DOI Listing
September 2010

A new therapy paradigm for prostate cancer founded on clinical observations.

Clin Cancer Res 2010 Feb 9;16(4):1100-7. Epub 2010 Feb 9.

Department of Genitourinary Medical Oncology and David H Koch Center for Applied Research of Genitourinary Cancers, University of Athens, Athens, Greece.

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http://dx.doi.org/10.1158/1078-0432.CCR-09-1215DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3891669PMC
February 2010

Informative clinical investigation: a demanding taskmaster.

J Clin Oncol 2009 Oct 31;27(30):4937-8. Epub 2009 Aug 31.

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http://dx.doi.org/10.1200/JCO.2009.23.8063DOI Listing
October 2009

Candidate pathways and genes for prostate cancer: a meta-analysis of gene expression data.

BMC Med Genomics 2009 Aug 4;2:48. Epub 2009 Aug 4.

Department of Genitourinary Medical Oncology, The University of Texas M, D, Anderson Cancer Center, Houston, TX, USA.

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http://dx.doi.org/10.1186/1755-8794-2-48DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2731785PMC
August 2009

RANKL inhibition: clinical implications for the management of patients with multiple myeloma and solid tumors with bone metastases.

Expert Opin Biol Ther 2009 Apr;9(4):465-79

Alexandra University Hospital, University of Athens School of Medicine, Department of Clinical Therapeutics, 5 Marathonomahon street, Drosia Attikis, 14572, Athens, Greece.

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http://www.tandfonline.com/doi/full/10.1517/1471259090284561
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http://dx.doi.org/10.1517/14712590902845610DOI Listing
April 2009

Inhibition of Mxi1 suppresses HIF-2alpha-dependent renal cancer tumorigenesis.

Cancer Biol Ther 2008 Oct 3;7(10):1619-27. Epub 2008 Oct 3.

Department of Genitourinary Medical Oncology, MD Anderson Cancer Center, Houston, Texas 77030, USA.

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http://dx.doi.org/10.4161/cbt.7.10.6583DOI Listing
October 2008

Advanced epithelial ovarian cancer in the elderly: chemotherapy tolerance and outcome.

Anticancer Res 2007 Jan-Feb;27(1B):611-7

Department of Clinical Therapeutics, Athens University School of Medicine, Athens, Greece.

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April 2007

Biweekly gemcitabine and cisplatin in platinum-resistant/refractory, paclitaxel-pretreated, ovarian and peritoneal carcinoma.

Gynecol Oncol 2007 Mar 17;104(3):580-5. Epub 2006 Oct 17.

Department of Clinical Therapeutics, University of Athens, Medical School, 31 Komninon st, Haidari, 12462 Athens, Greece.

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http://dx.doi.org/10.1016/j.ygyno.2006.09.006DOI Listing
March 2007

Initial modulation of the tumor microenvironment accounts for thalidomide activity in prostate cancer.

Clin Cancer Res 2007 Feb;13(4):1224-31

Department of Genitourinary Medical Oncology, The University of Texas M. D. Anderson Cancer Center, Houston, Texas 77030, USA.

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http://dx.doi.org/10.1158/1078-0432.CCR-06-1938DOI Listing
February 2007

Review of late complications of treatment and late relapse in testicular cancer.

J Natl Compr Canc Netw 2006 Nov;4(10):1059-70

Department of Genitourinary Medical Oncology, The University of Texas M. D. Anderson Cancer Center, Houston, Texas 77030, USA.

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http://dx.doi.org/10.6004/jnccn.2006.0088DOI Listing
November 2006

Brain metastases from epithelial ovarian cancer. The Hellenic Cooperative Oncology Group (HeCOG) experience and review of the literature.

Anticancer Res 2005 Sep-Oct;25(5):3553-8

Second Department of Internal Medicine-Propaedeutic, Oncology Section, University General Hospital Attikon, Haidari, Athens, Greece.

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October 2005

Outpatient treatment of low-risk neutropenic fever in cancer patients using oral moxifloxacin.

Cancer 2005 Jun;103(12):2629-35

Department of Clinical Therapeutics, University of Athens Medical School, Athens, Greece.

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http://dx.doi.org/10.1002/cncr.21089DOI Listing
June 2005

Advanced stage mucinous epithelial ovarian cancer: the Hellenic Cooperative Oncology Group experience.

Gynecol Oncol 2005 May;97(2):436-41

Second Department of Internal Medicine-Propaedeutic, Oncology Section, University General Hospital ATTIKON, Gravias 5B, Aghia Paraskevi, 153 42 Athens, Greece.

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http://dx.doi.org/10.1016/j.ygyno.2004.12.056DOI Listing
May 2005

Treatment of ovarian germ cell tumors with a 3-day bleomycin, etoposide, and cisplatin regimen: a prospective multicenter study.

Gynecol Oncol 2004 Dec;95(3):695-700

Departments of Clinical Therapeutics, Obstetrics and Gynecology, University of Athens School of Medicine, 31 Komninon Street, Haidari 124 62, Athens, Greece.

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http://dx.doi.org/10.1016/j.ygyno.2004.08.018DOI Listing
December 2004