Elena Volokhina

Elena Volokhina

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Elena Volokhina

Elena Volokhina

Publications by authors named "Elena Volokhina"

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26Publications

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The role of properdin in complement-mediated renal diseases: a new player in complement-inhibiting therapy?

Pediatr Nephrol 2019 08 23;34(8):1349-1367. Epub 2018 Aug 23.

Radboud Institute for Molecular Life Sciences, Department of Pediatric Nephrology, Amalia Children's Hospital, Radboud University Medical Center, Geert Grooteplein Zuid 10, PO Box 9101, 6525 GA, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1007/s00467-018-4042-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6579773PMC
August 2019

Biosynthetic homeostasis and resilience of the complement system in health and infectious disease.

EBioMedicine 2019 Jul 29;45:303-313. Epub 2019 Jun 29.

Section Pediatric Infectious Diseases, Laboratory of Medical Immunology, Department of Laboratory Medicine, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, The Netherlands; Radboud Center for Infectious Diseases, Radboud University Medical Center, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1016/j.ebiom.2019.06.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6642076PMC
July 2019

Overactivity of Alternative Pathway Convertases in Patients With Complement-Mediated Renal Diseases.

Front Immunol 2018 4;9:612. Epub 2018 Apr 4.

Department of Pediatric Nephrology, Radboud Institute for Molecular Life Sciences, Amalia Children's Hospital, Radboud University Medical Center, Nijmegen, Netherlands.

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http://dx.doi.org/10.3389/fimmu.2018.00612DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5893837PMC
June 2019

Glyco-iELISA: a highly sensitive and unambiguous serological method to diagnose STEC-HUS caused by serotype O157.

Pediatr Nephrol 2019 04 26;34(4):631-639. Epub 2018 Oct 26.

Radboud Institute for Molecular Life Sciences, Amalia Children's Hospital, Department of Pediatric Nephrology, Radboud University Medical Center, P.O. Box 9101, 6500 HB, Nijmegen, The Netherlands.

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http://link.springer.com/10.1007/s00467-018-4118-9
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http://dx.doi.org/10.1007/s00467-018-4118-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6394669PMC
April 2019

Placental passage of eculizumab and complement blockade in a newborn.

Kidney Int 2019 04;95(4):996

Department of Nephrology, Radboud University Medical Center, Nijmegen, The Netherlands.

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https://linkinghub.elsevier.com/retrieve/pii/S00852538193010
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http://dx.doi.org/10.1016/j.kint.2019.01.012DOI Listing
April 2019

Safety and effectiveness of restrictive eculizumab treatment in atypical haemolytic uremic syndrome.

Nephrol Dial Transplant 2018 04;33(4):635-645

Department of Nephrology, Radboud University Medical Center, Nijmegen, The Netherlands.

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https://academic.oup.com/ndt/article/33/4/635/3922789
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http://dx.doi.org/10.1093/ndt/gfx196DOI Listing
April 2018

Gain of function mutant of complement factor B K323E mimics pathogenic C3NeF autoantibodies in convertase assays.

Autoimmunity 2018 02 8;51(1):18-24. Epub 2018 Jan 8.

a Department of Medical Biotechnology , Intercollegiate Faculty of Biotechnology UG-GUMED , Gdańsk , Poland.

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http://dx.doi.org/10.1080/08916934.2017.1423286DOI Listing
February 2018

Genetic predisposition to infection in a case of atypical hemolytic uremic syndrome.

J Hum Genet 2018 Jan 13;63(1):93-96. Epub 2017 Nov 13.

Department of Pediatric Nephrology, Radboud University Medical Center, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1038/s10038-017-0356-0DOI Listing
January 2018

Eculizumab-C5 complexes express a C5a neoepitope in vivo: Consequences for interpretation of patient complement analyses.

Mol Immunol 2017 09 10;89:111-114. Epub 2017 Jun 10.

Department of Immunology, Oslo University Hospital Rikshospitalet, Oslo, Norway; K.G. Jebsen Inflammatory Research Center, University of Oslo, Oslo, Norway; Research Laboratory, Nordland Hospital, Bodø, Norway; Faculty of Health Sciences, K.G. Jebsen TREC, University of Tromsø, Tromsø, Norway; Centre of Molecular Inflammation Research, Norwegian University of Science and Technology, Trondheim, Norway. Electronic address:

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http://dx.doi.org/10.1016/j.molimm.2017.05.021DOI Listing
September 2017

Fecal diagnostics in combination with serology: best test to establish STEC-HUS.

Pediatr Nephrol 2016 11 30;31(11):2163-70. Epub 2016 May 30.

Department of Pediatric Nephrology, Radboudumc Amalia Children's Hospital, Radboud University Medical Center, P.O. Box 1901, 6500 HB, Nijmegen, Netherlands.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5039220PMC
http://dx.doi.org/10.1007/s00467-016-3420-7DOI Listing
November 2016

Regulators of complement activity mediate inhibitory mechanisms through a common C3b-binding mode.

EMBO J 2016 05 24;35(10):1133-49. Epub 2016 Mar 24.

Crystal and Structural Chemistry, Bijvoet Center for Biomolecular Research, Department of Chemistry, Faculty of Science Utrecht University, Utrecht, The Netherlands

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http://dx.doi.org/10.15252/embj.201593673DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4868954PMC
May 2016

Recovery of renal function after long-term dialysis and resolution of cardiomyopathy in a patient with aHUS receiving eculizumab.

BMJ Case Rep 2016 Feb 15;2016. Epub 2016 Feb 15.

Department of Paediatric Nephrology, Radboud University Medical Center, Nijmegen, The Netherlands Department of Laboratory Medicine, Radboud University Medical Center, Nijmegen, The Netherlands.

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http://casereports.bmj.com/content/2016/bcr-2015-213928.full
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http://casereports.bmj.com/lookup/doi/10.1136/bcr-2015-21392
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http://dx.doi.org/10.1136/bcr-2015-213928DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4840264PMC
February 2016

Sensitive, reliable and easy-performed laboratory monitoring of eculizumab therapy in atypical hemolytic uremic syndrome.

Clin Immunol 2015 Oct 23;160(2):237-43. Epub 2015 Jun 23.

Research Laboratory, Nordland Hospital, P. O. Box 1480, 8092 Bodø, Norway; Faculty of Health Sciences, K.G. Jebsen TREC, University of Tromsø, P. O. Box 6050 Langnes, 9037 Tromsø, Norway; Centre of Molecular Inflammation Research, Norwegian University of Science and Technology, NO-7491 Trondheim, Norway; Department of Immunology, Oslo University Hospital, and K.G Jebsen IRC, University of Oslo, P.B. 4950 Nydalen, NO-0424 Oslo, Norway. Electronic address:

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http://dx.doi.org/10.1016/j.clim.2015.05.018DOI Listing
October 2015

Eculizumab treatment efficiently prevents C5 cleavage without C5a generation in vivo.

Blood 2015 Jul;126(2):278-9

Research Laboratory, Nordland Hospital, Bodø, Norway Department of Immunology, Oslo University Hospital, K.G. Jebsen Inflammation Research Centre, University of Oslo, Oslo, Norway Faculty of Health Sciences, K.G. Jebsen Thrombosis Research and Expertise Center, University of Tromsø, Tromsø, Norway Centre of Molecular Inflammation Research, Norwegian University of Science and Technology, Trondheim, Norway.

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http://dx.doi.org/10.1182/blood-2015-03-637645DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4528083PMC
July 2015

Analysis of rare variants in the C3 gene in patients with age-related macular degeneration.

PLoS One 2014 15;9(4):e94165. Epub 2014 Apr 15.

Department of Ophthalmology, Radboud University Nijmegen Medical Centre, Nijmegen, the Netherlands; Radboud Institute for Molecular Life Sciences, Radboud University Nijmegen Medical Centre, Nijmegen, the Netherlands; Department of Human Genetics, Radboud University Nijmegen Medical Centre, Nijmegen, the Netherlands.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0094165PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3988049PMC
January 2015

Species-specificity of the BamA component of the bacterial outer membrane protein-assembly machinery.

PLoS One 2013 20;8(12):e85799. Epub 2013 Dec 20.

Department of Molecular Microbiology and Institute of Biomembranes, Utrecht University, Utrecht, The Netherlands.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0085799PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3869937PMC
July 2014

Novel C3 mutation p.Lys65Gln in aHUS affects complement factor H binding.

Pediatr Nephrol 2012 Sep 6;27(9):1519-24. Epub 2012 Jun 6.

Department of Pediatric Nephrology (804), Radboud University Nijmegen Medical Centre, P.O. Box 9101, 6500 HB, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1007/s00467-012-2183-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3407361PMC
September 2012

Atypical hemolytic uremic syndrome and genetic aberrations in the complement factor H-related 5 gene.

J Hum Genet 2012 Jul 24;57(7):459-64. Epub 2012 May 24.

Department of Pediatric Nephrology, Radboud University Medical Centre, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1038/jhg.2012.57DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3407369PMC
July 2012

Role of the periplasmic chaperones Skp, SurA, and DegQ in outer membrane protein biogenesis in Neisseria meningitidis.

J Bacteriol 2011 Apr 4;193(7):1612-21. Epub 2011 Feb 4.

Department of Molecular Microbiology, Utrecht University, Padualaan 8, 3584 CH Utrecht, Netherlands.

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http://dx.doi.org/10.1128/JB.00532-10DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3067652PMC
April 2011

Genetic disorders in complement (regulating) genes in patients with atypical haemolytic uraemic syndrome (aHUS).

Nephrol Dial Transplant 2010 Jul 26;25(7):2195-202. Epub 2010 Jan 26.

Department of Paediatric Nephrology, Radboud University Nijmegen Medical Centre (RUNMC), P.O. Box 9101, 6500 HB Nijmegen, The Netherlands.

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http://dx.doi.org/10.1093/ndt/gfq010DOI Listing
July 2010

The beta-barrel outer membrane protein assembly complex of Neisseria meningitidis.

J Bacteriol 2009 Nov 18;191(22):7074-85. Epub 2009 Sep 18.

Department of Molecular Microbiology, Utrecht University, Padualaan 8, 3584 CH Utrecht, The Netherlands.

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http://dx.doi.org/10.1128/JB.00737-09DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2772484PMC
November 2009

Assembly factor Omp85 recognizes its outer membrane protein substrates by a species-specific C-terminal motif.

PLoS Biol 2006 Nov;4(11):e377

Department of Molecular Microbiology and Institute of Biomembranes, Utrecht University, Utrecht, The Netherlands.

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http://dx.doi.org/10.1371/journal.pbio.0040377DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1634882PMC
November 2006