Elena Vigorito

Elena Vigorito

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Elena Vigorito

Elena Vigorito

Publications by authors named "Elena Vigorito"

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MicroRNA-155 is essential for the optimal proliferation and survival of plasmablast B cells.

Life Sci Alliance 2019 Jun 16;2(3). Epub 2019 May 16.

Lymphocyte Signalling and Development, Babraham Institute, Cambridge, UK

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http://dx.doi.org/10.26508/lsa.201800244DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6524163PMC
June 2019

Fine-Scale Mapping at 9p22.2 Identifies Candidate Causal Variants That Modify Ovarian Cancer Risk in BRCA1 and BRCA2 Mutation Carriers.

Authors:
Elena Vigorito Karoline B Kuchenbaecker Jonathan Beesley Julian Adlard Bjarni A Agnarsson Irene L Andrulis Banu K Arun Laure Barjhoux Muriel Belotti Javier Benitez Andreas Berger Anders Bojesen Bernardo Bonanni Carole Brewer Trinidad Caldes Maria A Caligo Ian Campbell Salina B Chan Kathleen B M Claes David E Cohn Jackie Cook Mary B Daly Francesca Damiola Rosemarie Davidson Antoine de Pauw Capucine Delnatte Orland Diez Susan M Domchek Martine Dumont Katarzyna Durda Bernd Dworniczak Douglas F Easton Diana Eccles Christina Edwinsdotter Ardnor Ros Eeles Bent Ejlertsen Steve Ellis D Gareth Evans Lidia Feliubadalo Florentia Fostira William D Foulkes Eitan Friedman Debra Frost Pragna Gaddam Patricia A Ganz Judy Garber Vanesa Garcia-Barberan Marion Gauthier-Villars Andrea Gehrig Anne-Marie Gerdes Sophie Giraud Andrew K Godwin David E Goldgar Christopher R Hake Thomas V O Hansen Sue Healey Shirley Hodgson Frans B L Hogervorst Claude Houdayer Peter J Hulick Evgeny N Imyanitov Claudine Isaacs Louise Izatt Angel Izquierdo Lauren Jacobs Anna Jakubowska Ramunas Janavicius Katarzyna Jaworska-Bieniek Uffe Birk Jensen Esther M John Joseph Vijai Beth Y Karlan Karin Kast KConFab Investigators Sofia Khan Ava Kwong Yael Laitman Jenny Lester Fabienne Lesueur Annelie Liljegren Jan Lubinski Phuong L Mai Siranoush Manoukian Sylvie Mazoyer Alfons Meindl Arjen R Mensenkamp Marco Montagna Katherine L Nathanson Susan L Neuhausen Heli Nevanlinna Dieter Niederacher Edith Olah Olufunmilayo I Olopade Kai-Ren Ong Ana Osorio Sue Kyung Park Ylva Paulsson-Karlsson Inge Sokilde Pedersen Bernard Peissel Paolo Peterlongo Georg Pfeiler Catherine M Phelan Marion Piedmonte Bruce Poppe Miquel Angel Pujana Paolo Radice Gad Rennert Gustavo C Rodriguez Matti A Rookus Eric A Ross Rita Katharina Schmutzler Jacques Simard Christian F Singer Thomas P Slavin Penny Soucy Melissa Southey Doris Steinemann Dominique Stoppa-Lyonnet Grzegorz Sukiennicki Christian Sutter Csilla I Szabo Muy-Kheng Tea Manuel R Teixeira Soo-Hwang Teo Mary Beth Terry Mads Thomassen Maria Grazia Tibiletti Laima Tihomirova Silvia Tognazzo Elizabeth J van Rensburg Liliana Varesco Raymonda Varon-Mateeva Athanassios Vratimos Jeffrey N Weitzel Lesley McGuffog Judy Kirk Amanda Ewart Toland Ute Hamann Noralane Lindor Susan J Ramus Mark H Greene Fergus J Couch Kenneth Offit Paul D P Pharoah Georgia Chenevix-Trench Antonis C Antoniou

PLoS One 2016 27;11(7):e0158801. Epub 2016 Jul 27.

Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0158801PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4963094PMC
July 2017

The miR-155-PU.1 axis acts on Pax5 to enable efficient terminal B cell differentiation.

J Exp Med 2014 Oct 6;211(11):2183-98. Epub 2014 Oct 6.

Lymphocyte Signaling and Development and The Bioinformatics Group, The Babraham Institute, Babraham Research Campus, Cambridge, Cambridgeshire CB22 3AT, England, UK

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http://dx.doi.org/10.1084/jem.20140338DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4203942PMC
October 2014

Noncoding RNA and its associated proteins as regulatory elements of the immune system.

Nat Immunol 2014 Jun;15(6):484-91

Laboratory of Lymphocyte Signalling and Development, The Babraham Institute, Babraham Research Campus, Cambridge, UK.

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http://www.nature.com/articles/ni.2887
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http://dx.doi.org/10.1038/ni.2887DOI Listing
June 2014

Macrophage microRNA-155 promotes cardiac hypertrophy and failure.

Circulation 2013 Sep 16;128(13):1420-32. Epub 2013 Aug 16.

Center for Heart Failure Research, Department of Cardiology (S.H., M.F.C., W.V., P.C., R.E.W.v.L., K.C., T.P., M.H., M.v.B., A.-P.P., B.S.), Department of Molecular Genetics (L.S., M.P.J.d.W.), Department of Pathology (E.W., E.L.), Department of Pharmacology (B.J.J.), Department of Cardiology (L.J.d.W.), and Department of Internal Medicine (K.W.), Cardiovascular Research Institute Maastricht, Maastricht University, Maastricht, the Netherlands; Interuniversity Cardiology Institute of the Netherlands, Utrecht, the Netherlands (S.H.); Center for Molecular and Cardiovascular Biology, Department of Cardiovascular Sciences, Leuven, Belgium (S.H., P.C., A.-P.P.); Department of Medical Biochemistry (L.S., E.L., M.P.J.d.W.) and Heart Failure Research Center (E.E.C., Y.M.P.), Academic Medical Center, Amsterdam, the Netherlands; Cluster of Excellence Cell Networks, Department of Infectious Diseases/Virology, Virus Host Interactions, Heidelberg University, Heidelberg, Germany (D.G., N.S.); Laboratory of Lymphocyte Signaling and Development, Babraham Institute, Cambridge, UK (E.V.); Institute for Molecular and Translational Therapeutic Strategies, Hannover Medical School, Hannover, Germany (T.T.); Medical Microbiology, Maastricht University, Maastricht, the Netherlands (F.S.); King's BHF Centre, King's College London, London UK (X.Y., M.M.); Institute for Cardiovascular Prevention, Ludwig Maximilians University, Munich, Germany (E.L.); and Molecular Medicine Laboratory, International Centre for Genetic Engineering and Biotechnology, Trieste, Italy (S.Z., M.G.).

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http://circ.ahajournals.org/content/early/2013/08/16/CIRCULA
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http://circ.ahajournals.org/cgi/doi/10.1161/CIRCULATIONAHA.1
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http://dx.doi.org/10.1161/CIRCULATIONAHA.112.001357DOI Listing
September 2013

MiR-210 is induced by Oct-2, regulates B cells, and inhibits autoantibody production.

J Immunol 2013 Sep 19;191(6):3037-3048. Epub 2013 Aug 19.

Cambridge Institute for Medical Research and Department of Medicine, University of Cambridge School of Clinical Medicine, Addenbrooke's Hospital, Hills Road, Cambridge, CB2 0XY, UK.

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http://dx.doi.org/10.4049/jimmunol.1301289DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4162006PMC
September 2013

miR-155: an ancient regulator of the immune system.

Immunol Rev 2013 May;253(1):146-57

Laboratory of Lymphocyte Signalling and Development, The Babraham Institute, Babraham Research Campus, Cambridge, UK.

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http://dx.doi.org/10.1111/imr.12057DOI Listing
May 2013

Chemical structure requirements and cellular targeting of microRNA-122 by peptide nucleic acids anti-miRs.

Nucleic Acids Res 2012 Mar 8;40(5):2152-67. Epub 2011 Nov 8.

Medical Research Council, Laboratory of Molecular Biology, Hills Road, Cambridge CB2 0QH, UK.

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http://dx.doi.org/10.1093/nar/gkr885DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3300011PMC
March 2012

MicroRNA fate upon targeting with anti-miRNA oligonucleotides as revealed by an improved Northern-blot-based method for miRNA detection.

RNA 2011 May 25;17(5):933-43. Epub 2011 Mar 25.

Medical Research Council, Laboratory of Molecular Biology, Cambridge, United Kingdom.

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http://dx.doi.org/10.1261/rna.2533811DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3078742PMC
May 2011

Efficient inhibition of miR-155 function in vivo by peptide nucleic acids.

Nucleic Acids Res 2010 Jul 11;38(13):4466-75. Epub 2010 Mar 11.

Medical Research Council, Laboratory of Molecular Biology, Cambridge CB2 0QH, UK.

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http://dx.doi.org/10.1093/nar/gkq160DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2910044PMC
July 2010

Vav GEFs regulate macrophage morphology and adhesion-induced Rac and Rho activation.

Exp Cell Res 2009 Nov 26;315(19):3345-58. Epub 2009 Aug 26.

King's College London, Randall Division of Cell and Molecular Biophysics, Guy's Campus, London, UK.

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http://dx.doi.org/10.1016/j.yexcr.2009.08.010DOI Listing
November 2009

Cutting edge: the Foxp3 target miR-155 contributes to the development of regulatory T cells.

J Immunol 2009 Mar;182(5):2578-82

Laboratory of Lymphocyte Signalling and Development, Babraham Institute, Cambridge, United Kingdom.

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http://dx.doi.org/10.4049/jimmunol.0803162DOI Listing
March 2009

Regulation of B- and T-cell differentiation by a single microRNA.

Biochem Soc Trans 2008 Jun;36(Pt 3):531-3

Laboratory of Lymphocyte Signalling and Development, Babraham Institute, Cambridge CB22 3AT, UK.

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http://biochemsoctrans.org/lookup/doi/10.1042/BST0360531
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http://dx.doi.org/10.1042/BST0360531DOI Listing
June 2008

The effect of deleting p110delta on the phenotype and function of PTEN-deficient B cells.

J Immunol 2008 Jan;180(2):739-46

Laboratory of Lymphocyte Signalling and Development, The Babraham Institute, Babraham, Cambridge, United Kingdom.

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http://dx.doi.org/10.4049/jimmunol.180.2.739DOI Listing
January 2008

Activation of the small GTPase Rac2 via the B cell receptor regulates B cell adhesion and immunological-synapse formation.

Immunity 2008 Jan;28(1):88-99

Lymphocyte Interaction Laboratory, Cancer Research UK, London Research Institute, Lincoln's Inn Fields Laboratories, 44 Lincoln's Inn Fields, London WC2A 3PX, UK.

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http://linkinghub.elsevier.com/retrieve/pii/S107476130700581
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http://dx.doi.org/10.1016/j.immuni.2007.12.003DOI Listing
January 2008

Vav family proteins are required for optimal regulation of PLCgamma2 by integrin alphaIIbbeta3.

Biochem J 2007 Feb;401(3):753-61

Centre for Cardiovascular Sciences, Institute of Biomedical Research, Division of Medical Sciences, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK.

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http://dx.doi.org/10.1042/BJ20061508DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1770845PMC
February 2007

Differential requirements of PI3K subunits for BCR or BCR/CD19-induced ERK activation.

Adv Exp Med Biol 2006 ;584:43-52

Laboratory of Lymphocyte Signaling and Development, The Babraham Institute, Babraham, Cambridge CB2 4AT, UK.

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http://dx.doi.org/10.1007/0-387-34132-3_4DOI Listing
October 2006

Synergistic activation of PKD by the B cell antigen receptor and CD19 requires PI3K, Vav1 and PLCgamma.

Cell Signal 2006 Sep 27;18(9):1455-60. Epub 2005 Dec 27.

Laboratory of Lymphocyte Signaling and Development, The Babraham Institute, Babraham Research Campus, Cambridge CB2 4AT, UK.

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http://dx.doi.org/10.1016/j.cellsig.2005.11.008DOI Listing
September 2006

RhoG regulates the neutrophil NADPH oxidase.

J Immunol 2006 May;176(9):5314-20

Inositide Laboratory, Babraham Institute, Babraham Research Campus, Cambridge, UK.

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http://dx.doi.org/10.4049/jimmunol.176.9.5314DOI Listing
May 2006

Vav1 and Vav2 play different roles in macrophage migration and cytoskeletal organization.

Exp Cell Res 2005 Nov 31;310(2):303-10. Epub 2005 Aug 31.

Ludwig Institute for Cancer Research, Royal Free and University College Medical School Branch, 91 Riding House Street, London W1W 7BS, UK.

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http://dx.doi.org/10.1016/j.yexcr.2005.07.015DOI Listing
November 2005

Vav proteins regulate peripheral B-cell survival.

Blood 2005 Oct 7;106(7):2391-8. Epub 2005 Jun 7.

Laboratory of Lymphocyte Signaling and Development, Molecular Immunology Programme, The Babraham Institute, Babraham, Cambridge CB2 4AT, United Kingdom.

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http://www.bloodjournal.org/cgi/doi/10.1182/blood-2004-12-48
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http://dx.doi.org/10.1182/blood-2004-12-4894DOI Listing
October 2005

Role of the p110delta PI 3-kinase in integrin and ITAM receptor signalling in platelets.

Platelets 2005 May-Jun;16(3-4):191-202

Centre for Cardiovascular Sciences, Division of Medical Sciences, Institute of Biomedical Research, Wolfson Drive, The Medical School, University of Birmingham, Edgbaston, Birmingham, UK.

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http://dx.doi.org/10.1080/09537100400016711DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1868960PMC
October 2005

Phosphatidylinositol 3-kinase is required for the transcriptional activation of cyclin D2 in BCR activated primary mouse B lymphocytes.

Eur J Immunol 2005 Sep;35(9):2748-61

Cancer Research-UK laboratories, Department of Cancer Medicine, MRC Cyclotron Building, Imperial College London, Hammersmith Hospital, London, UK.

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http://dx.doi.org/10.1002/eji.200425812DOI Listing
September 2005

Cutting edge: T cell development requires the combined activities of the p110gamma and p110delta catalytic isoforms of phosphatidylinositol 3-kinase.

J Immunol 2005 Sep;175(5):2783-7

Laboratory of Lymphocyte Signalling and Development, The Babraham Institute, Babraham, Cambridge, United Kingdom.

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http://dx.doi.org/10.4049/jimmunol.175.5.2783DOI Listing
September 2005

Vav proteins are required for B-lymphocyte responses to LPS.

Blood 2005 Jul 5;106(2):635-40. Epub 2005 Apr 5.

Laboratory of Lymphocyte Signaling and Development, The Babraham Institute, Babraham Research Campus, Cambridge CB2 4AT, United Kingdom.

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http://dx.doi.org/10.1182/blood-2004-10-3919DOI Listing
July 2005

Vav1 and vav3 have critical but redundant roles in mediating platelet activation by collagen.

J Biol Chem 2004 Dec 27;279(52):53955-62. Epub 2004 Sep 27.

Department of Pharmacology, University of Oxford, Mansfield Road, Oxford, OX1 3QT, UK.

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http://dx.doi.org/10.1074/jbc.M410355200DOI Listing
December 2004

Vav-dependent and vav-independent phosphatidylinositol 3-kinase activation in murine B cells determined by the nature of the stimulus.

J Immunol 2004 Sep;173(5):3209-14

Laboratory of Lymphocyte Signaling and Development, Molecular Immunology Programme, Babraham Institute, Babraham, Cambridge, United Kingdom.

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http://dx.doi.org/10.4049/jimmunol.173.5.3209DOI Listing
September 2004

PLCgamma2 regulates Bcl-2 levels and is required for survival rather than differentiation of marginal zone and follicular B cells.

Eur J Immunol 2004 Aug;34(8):2237-47

Laboratory of Lymphocyte Signalling and Development, The Babraham Institute, Babraham, Cambridge CB2 4AT, GB.

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http://doi.wiley.com/10.1002/eji.200425054
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http://dx.doi.org/10.1002/eji.200425054DOI Listing
August 2004

Immunological function in mice lacking the Rac-related GTPase RhoG.

Mol Cell Biol 2004 Jan;24(2):719-29

Laboratory of Lymphocyte Signaling and Development, Molecular Immunology Programme, The Babraham Institute, Babraham, Cambridge CB2 4AT, UK.

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http://mcb.asm.org/content/24/2/719.full.pdf
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC343784PMC
http://dx.doi.org/10.1128/mcb.24.2.719-729.2004DOI Listing
January 2004

Regulation of Vav localization in membrane rafts by adaptor molecules Grb2 and BLNK.

Immunity 2003 Jun;18(6):777-87

Department of Molecular Genetics, Institute for Liver Research, Kansai Medical University, 10-15 Fumizono-cho, Moriguchi 570-8506, Japan.

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June 2003

RhoG regulates gene expression and the actin cytoskeleton in lymphocytes.

Oncogene 2003 Jan;22(3):330-42

Laboratory for Lymphocyte Signalling and Development, Molecular Immunology Programme, The Babraham Institute, Cambridge, UK.

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http://dx.doi.org/10.1038/sj.onc.1206116DOI Listing
January 2003

A crucial role for the p110delta subunit of phosphatidylinositol 3-kinase in B cell development and activation.

J Exp Med 2002 Sep;196(6):753-63

Laboratory of Lymphocyte Signaling and Development, Molecular Immunology Programme, The Babraham Institute, Babraham, Cambridge CB2 4AT, United Kingdom.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2194055PMC
http://dx.doi.org/10.1084/jem.20020805DOI Listing
September 2002

True anti-anionic phospholipid immunoglobulin M antibodies can exert lupus anticoagulant activity.

Br J Haematol 2002 Mar;116(4):875-86

Service of Immunology, Hospital Clínic Universitari, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona University School of Medicine, Barcelona, Spain.

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http://dx.doi.org/10.1046/j.0007-1048.2002.03335.xDOI Listing
March 2002