Elena Silvestri

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Elena Silvestri

Publications by authors named "Elena Silvestri"

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94Publications

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Effect of Iodothyronines on Thermogenesis: Focus on Brown Adipose Tissue.

Front Endocrinol (Lausanne) 2018 23;9:254. Epub 2018 May 23.

Department of Biology, University of Naples Federico II, Naples, Italy.

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May 2018

Timing of onset affects arthritis presentation pattern in antisyntethase syndrome.

Clin Exp Rheumatol 2018 Jan-Feb;36(1):44-49. Epub 2017 Jul 26.

Division of Rheumatology, University and IRCCS Policlinico S. Matteo Foudation, Pavia, Italy.

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April 2018

Exenatide exerts cognitive effects by modulating the BDNF-TrkB neurotrophic axis in adult mice.

Neurobiol Aging 2018 Apr 19;64:33-43. Epub 2017 Dec 19.

Center of Excellence on Aging and Translational Medicine - CeSI-MeT, University G. d'Annunzio of Chieti-Pescara, Italy; Department of Neuroscience, Imaging, and Clinical Sciences, University G. d'Annunzio of Chieti-Pescara, Italy; Departments of Neurology and Pharmacology, Institute for Mind Impairments and Neurological Disorders, University of California - Irvine, Irvine, USA. Electronic address:

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April 2018

CSF/serum matrix metallopeptidase-9 ratio discriminates neuro Behçet from multiple sclerosis.

Ann Clin Transl Neurol 2018 Apr 10;5(4):493-498. Epub 2018 Mar 10.

Department of Neurosciences, Psychology, Drug and Child Health University of Florence Florence Italy.

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April 2018

Certolizumab Pegol treatment in Behcet's disease with different organ involvement: A multicenter retrospective observational study.

Mod Rheumatol 2017 Nov 21;27(6):1031-1035. Epub 2017 Feb 21.

c Research Center of Systemic Autoinflammatory Diseases and Behçet's Disease Clinic, Department of Medical Sciences, Surgery and Neurosciences , University of Siena , Siena , Italy.

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November 2017

Redox status alterations during the competitive season in élite soccer players: focus on peripheral leukocyte-derived ROS.

Intern Emerg Med 2017 Sep 30;12(6):777-788. Epub 2017 Mar 30.

Department of Experimental and Clinical Biomedical Sciences "Mario Serio", University of Florence, Viale Morgagni 50, 50134, Florence, Italy.

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September 2017

Long-term efficacy and safety of golimumab in the treatment of multirefractory Behçet's disease.

Clin Rheumatol 2017 Sep 11;36(9):2063-2069. Epub 2017 Apr 11.

Research Center of Systemic Autoinflammatory Diseases and Behçet's Disease Clinic, Department of Medical Sciences, Surgery and Neurosciences, University of Siena, Siena, Italy.

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September 2017

Both 3,5-Diiodo-L-Thyronine and 3,5,3'-Triiodo-L-Thyronine Prevent Short-term Hepatic Lipid Accumulation via Distinct Mechanisms in Rats Being Fed a High-Fat Diet.

Front Physiol 2017 14;8:706. Epub 2017 Sep 14.

Dipartimento di Scienze e Tecnologie Ambientali, Biologiche e Farmaceutiche, Università degli Studi della Campania, "Luigi Vanvitelli" CasertaCaserta, Italy.

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September 2017

Rapid desensitization to anakinra-related delayed reaction: Need for a standardized protocol.

J Dermatol 2017 Aug 26;44(8):981-982. Epub 2016 Sep 26.

Allergy and Clinical Immunology Unit, Azienda Usl Toscana Centro, Prato, Italy.

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August 2017

Repeated low-dose courses of rituximab in SLE-associated antiphospholipid syndrome: Data from a tertiary dedicated centre.

Semin Arthritis Rheum 2017 02 12;46(4):e21-e23. Epub 2016 Aug 12.

Department of Experimental and Clinical Medicine, University of Firenze, Firenze, Italy.

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February 2017

Adalimumab effectiveness in Behçet's disease: short and long-term data from a multicenter retrospective observational study.

Clin Rheumatol 2017 Feb 27;36(2):451-455. Epub 2016 Sep 27.

Research Center of Systemic Autoinflammatory Diseases and Behçet's Disease Clinic, Department of Medical Sciences, Surgery and Neurosciences, University of Siena, Siena, Italy.

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February 2017

Cytotoxic Th1 and Th17 cells infiltrate the intestinal mucosa of Behcet patients and exhibit high levels of TNF-α in early phases of the disease.

Medicine (Baltimore) 2016 Dec;95(49):e5516

aDepartment of Experimental and Clinical Medicine, University of Florence bDepartment of Surgery and Translational Medicine cResearch Center of Systemic Autoinflammatory Diseases and Behçet's Disease Clinic, Department of Medical Sciences, Surgery and Neurosciences, University of Siena dSOD Interdisciplinary Internal Medicine, Center for Autoimmune Systemic Diseases -Behçet Center and Lupus Clinic - AOU Careggi eRheumatology and Clinical Immunology, Humanitas Research Hospital fBIOMETRA Department, University of Milan, Milan, Italy.

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December 2016

Sharing data of clinical trials.

Eur J Intern Med 2016 Sep 25;33:e25-6. Epub 2016 May 25.

Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy.

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September 2016

Thrombosis in Autoimmune Diseases: A Role for Immunosuppressive Treatments?

Semin Thromb Hemost 2016 Sep 6;42(6):650-61. Epub 2016 Jun 6.

Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy.

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September 2016

SIRT1 activity is decreased in lesional psoriatic skin.

Intern Emerg Med 2016 Sep 10;11(6):891-3. Epub 2016 Jun 10.

Department of Experimental and Clinical Biomedical Sciences "Mario Serio", University of Florence, Largo Brambilla 3, 50134, Florence, Italy.

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September 2016

Tocilizumab-induced exacerbation of mucosal ulcers in a patient with multi-refractory Behçet׳s disease.

Semin Arthritis Rheum 2016 08 16;46(1):e1-2. Epub 2016 Mar 16.

Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy; Department of SOD Interdisciplinary Internal Medicine, Center for Autoimmune Systemic Diseases, Behçet Center and Lupus Clinic, AOU Careggi Hospital, Florence, Italy.

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August 2016

Favorable pregnancy outcome in a patient with systemic lupus erythematosus treated with belimumab: A confirmation report.

Semin Arthritis Rheum 2016 06 16;45(6):e26-7. Epub 2016 Mar 16.

Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy; Department of SOD Interdisciplinary Internal Medicine, Center for Autoimmune Systemic Diseases, Behçet Center and Lupus Clinic, AOU Careggi Hospital, Florence, Italy.

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June 2016

Efficacy and safety profile of anti-interleukin-1 treatment in Behçet's disease: a multicenter retrospective study.

Clin Rheumatol 2016 May 10;35(5):1281-6. Epub 2015 Jul 10.

Research Center of Systemic Autoinflammatory Diseases and Behçet's Disease Clinic, Department of Medical Sciences, Surgery and Neurosciences, University of Siena, Siena, Italy.

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May 2016

Neutrophil Activation Promotes Fibrinogen Oxidation and Thrombus Formation in Behçet Disease.

Circulation 2016 Jan 19;133(3):302-11. Epub 2015 Nov 19.

From Department of Experimental and Clinical Biomedical Sciences "Mario Serio" (M.B., G.B., N.T., C.F.) and Department of Experimental and Clinical Medicine (G.E., E.S., L.C., D.S., R.A., D.P.), University of Florence, Italy; Nephrology Unit, University Hospital of Parma, Italy (A.V.); Interdisciplinary Internal Medicine, Center for Autoimmune Systemic Diseases, Behçet Center and Lupus Clinic, AOU Careggi, Florence, Italy (L.E., D.P.); and Department of Clinical and Experimental Medicine, University Medical School and University Hospital of Parma, Italy (M.G.).

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January 2016

Triglyceride Mobilization from Lipid Droplets Sustains the Anti-Steatotic Action of Iodothyronines in Cultured Rat Hepatocytes.

Front Physiol 2015 12;6:418. Epub 2016 Jan 12.

Dipartimento di Scienze della Terra, dell'Ambiente e della Vita, Università di GenovaGenova, Italia; Istituto Nazionale Biostrutture e BiosistemiRoma, Italia.

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January 2016

A new cytofluorimetric approach to evaluate the circulating microparticles in subjects with antiphospholipid antibodies.

Thromb Res 2015 Dec 14;136(6):1252-8. Epub 2015 Oct 14.

Department of Experimental and Clinical Medicine, University of Florence, Italy; SOD Interdisciplinary Internal Medicine, Center for Autoimmune Systemic Diseases, Behçet Center and Lupus Clinic, AOU Careggi, Florence, Italy.

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December 2015

Macrophage activation syndrome in the course of monogenic autoinflammatory disorders.

Clin Rheumatol 2015 Aug 8;34(8):1333-9. Epub 2015 Apr 8.

Institute of Pediatrics, Università Cattolica Sacro Cuore, Fondazione Policlinico Universitario A. Gemelli, Rome, Italy.

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August 2015

Novel oral anticoagulants in atrial fibrillation: which novel oral anticoagulant for which patient?

J Cardiovasc Med (Hagerstown) 2015 Jul;16(7):512-9

aDepartment of Experimental and Clinical Medicine, University of Florence bSOD Patologia Medica, AOU Careggi, Florence cDepartment of Clinical Medicine and Surgery, University of Naples 'Federico II', Naples, Italy.

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July 2015

BN-PAGE-based approach to study thyroid hormones and mitochondrial function.

Methods Mol Biol 2015 ;1241:111-22

Dipartimento di Scienze e Tecnologie, Università degli Studi del Sannio, Via Port'Arsa 11, 82100, Benevento, Italy.

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June 2015

Microparticles: Bridging the Gap between Autoimmunity and Thrombosis.

Semin Thromb Hemost 2015 Jun 12;41(4):413-22. Epub 2015 May 12.

Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy.

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June 2015

An approach to differential diagnosis of antiphospholipid antibody syndrome and related conditions.

ScientificWorldJournal 2014 14;2014:341342. Epub 2014 Oct 14.

Department of Experimental and Clinical Medicine, University of Florence, 50134 Florence, Italy ; SOD Patologia Medica, Center for Autoimmune Systemic Diseases, Behçet Center and Lupus Clinic, AOU Careggi Hospital, 50134 Florence, Italy.

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May 2015

Behçet's syndrome patients exhibit specific microbiome signature.

Autoimmun Rev 2015 Apr 27;14(4):269-76. Epub 2014 Nov 27.

Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy; Medical Pathology, Center for Autoimmune Systemic Diseases, Behçet Center and Lupus Clinic, AOU Careggi, Florence, Italy.

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April 2015

Thrombosis in inflammatory bowel diseases: what's the link?

Thromb J 2015 2;13:14. Epub 2015 Apr 2.

Gastroenterology Department, AOU Careggi Regional Referral Center for Inflammatory Bowel Disease, Florence, Italy.

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April 2015

Thrombosis in vasculitis: from pathogenesis to treatment.

Thromb J 2015 16;13:15. Epub 2015 Apr 16.

Department of Experimental and Clinical Medicine, University of Florence, L.go G. Brambilla, 3, 50134 Florence, Italy.

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April 2015

The labyrinth of autoinflammatory disorders: a snapshot on the activity of a third-level center in Italy.

Clin Rheumatol 2015 Jan 24;34(1):17-28. Epub 2014 Jun 24.

Research Center of Systemic Autoinflammatory Diseases and Behçet's Disease, Department of Medical Sciences, Surgery and Neurosciences, University of Siena, Siena, Italy,

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January 2015

Proteomic approaches for the study of tissue specific effects of 3,5,3'-triiodo-L-thyronine and 3,5-diiodo-L-thyronine in conditions of altered energy metabolism.

Front Physiol 2014 17;5:491. Epub 2014 Dec 17.

Dipartimento di Scienze e Tecnologie, Università degli Studi del Sannio Benevento, Italy.

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January 2015

Reply: anti-IL1 blocking agents in drug-resistant Behçet's syndrome: our little case series.

Clin Exp Rheumatol 2014 Jul-Aug;32(4 Suppl 84):S172. Epub 2014 Apr 7.

SOD Patologia Medica, Center for Autoimmune Systemic Diseases, Behçet Center and Lupus Clinic, AOU Careggi, Florence, Italy.

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December 2014

Pharmacological prevention of venous thromboembolism in orthopaedic surgery.

Clin Cases Miner Bone Metab 2014 Sep;11(3):192-5

Department of Medical and Surgical Critical Care, University of Florence, Florence, Italy.

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September 2014

Behçet's syndrome pathophysiology and potential therapeutic targets.

Intern Emerg Med 2014 Apr 12;9(3):257-65. Epub 2014 Jan 12.

Department of Experimental and Clinical Medicine, University of Florence, L.go G. Brambilla 3, 50134, Florence, Italy,

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April 2014

Anti-TNF-α agents in vascular Behçet's disease.

Expert Rev Cardiovasc Ther 2014 Apr;12(4):415-6

SOD Patologia Medica, Center for Autoimmune Systemic Diseases - Behçet Center and Lupus Clinic, AOU Careggi, Florence, Italy.

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April 2014

Thyroid hormone analogues and derivatives: Actions in fatty liver.

World J Hepatol 2014 Mar;6(3):114-29

Maria Coppola, Daniela Glinni, Maria Moreno, Federica Cioffi, Elena Silvestri, Fernando Goglia, Department of Science and Technologies, University of Sannio, 82100 Benevento, Italy.

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March 2014

Vascular Behçet's disease: new insights in the management of thrombosis.

Expert Rev Cardiovasc Ther 2013 Dec 1;11(12):1583-5. Epub 2013 Nov 1.

SOD Patologia Medica, Center for Autoimmune Systemic Diseases - Behçet Center and Lupus Clinic, Dept of Experimental and Clinical Medicine, University of Florence, Florence, Italy.

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December 2013

Rare NLRP12 variants associated with the NLRP12-autoinflammatory disorder phenotype: an Italian case series.

Clin Exp Rheumatol 2013 May-Jun;31(3 Suppl 77):155-6. Epub 2013 Sep 9.

Research Center of Systemic Autoimmune and Autoinflammatory Diseases, Rheumatology Unit, Policlinico Le Scotte, University of Siena, Siena, Italy.

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November 2013

The "multifaceted" onset of vasculitis neuropathy.

Intern Emerg Med 2013 Oct 20;8(7):551-2. Epub 2012 Dec 20.

Center for autoimmune diseases, Lupus Clinic Unit, Careggi Hospital, Florence, Italy,

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October 2013

Digital ulcers secondary to Sneddon's syndrome successfully treated with Bosentan: not only useful in Systemic Sclerosis.

Auto Immun Highlights 2013 Aug 9;4(2):67-8. Epub 2012 Oct 9.

SOD Patologia Medica, Center for Autoimmune Diseases, Lupus Clinic, DAI Biomedicina, AOU Careggi, Largo Giovanni Brambilla 3, 50134 Florence, Italy.

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August 2013

(Healthy) ageing: focus on iodothyronines.

Int J Mol Sci 2013 Jul 4;14(7):13873-92. Epub 2013 Jul 4.

Dipartimento di Scienze e Tecnologie Ambientali, Biologiche e Farmaceutiche, Seconda Università degli Studi di Napoli, Via Vivaldi 43, Caserta 81100, Italy.

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July 2013

T cells in gastric cancer: friends or foes.

Clin Dev Immunol 2012 31;2012:690571. Epub 2012 May 31.

Patologia Medica, Dipartimento de Biomedicina, Azienda Ospedaliera Universitaria Careggi, Largo Brambilla 3, 50134 Firenze, Italy.

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October 2012

The risk stratification in atrial fibrillation.

Intern Emerg Med 2012 Oct;7 Suppl 3:S233-40

Department of Medical and Surgical Critical Care, University of Florence, Florence, Italy.

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October 2012

Helicobacter pylori management in primary care.

Intern Emerg Med 2012 Aug 22;7(4):297-8. Epub 2011 Sep 22.

PatologiaMedica, AOU Careggi, Largo Brambilla 3, 50134 Florence, Italy.

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August 2012

Helicobacter pylori: usefulness of an empirical fourth-line rifabutin-based regimen.

Expert Rev Gastroenterol Hepatol 2012 Aug;6(4):437-9

Patologia Medica, AOU Careggi Hospital, Florence, Italy.

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August 2012

Pulmonary hemorrhage: not only vasculitis.

Intern Emerg Med 2011 Dec 12;6(6):577-80. Epub 2011 Jul 12.

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December 2011

Nonthyrotoxic prevention of diet-induced insulin resistance by 3,5-diiodo-L-thyronine in rats.

Diabetes 2011 Nov 16;60(11):2730-9. Epub 2011 Sep 16.

Dipartimento di Scienze della Vita, Seconda Università degli Studi di Napoli, Caserta, Italy.

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November 2011

3,5-Diiodo-L-thyronine prevents high-fat-diet-induced insulin resistance in rat skeletal muscle through metabolic and structural adaptations.

FASEB J 2011 Oct 13;25(10):3312-24. Epub 2011 Jun 13.

Dipartimento di Scienze per la Biologia, la Geologia e l'Ambiente, Università degli Studi del Sannio, via Port'Arsa 11, 82100 Benevento, Italy.

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October 2011

Peroxisome Proliferator-Activated Receptor Delta: A Conserved Director of Lipid Homeostasis through Regulation of the Oxidative Capacity of Muscle.

PPAR Res 2008 ;2008:172676

Dipartimento di Scienze della Vita, Seconda Università degli Studi di Napoli, Via Vivaldi 43, 81100 Caserta, Italy.

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July 2011

PPARs: Nuclear Receptors Controlled by, and Controlling, Nutrient Handling through Nuclear and Cytosolic Signaling.

PPAR Res 2010 1;2010. Epub 2010 Aug 1.

Dipartimento di Scienze Biologiche ed Ambientali, Università degli Studi del Sannio, Via Port'Arsa 11, 82100 Benevento, Italy.

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July 2011

Studies of complex biological systems with applications to molecular medicine: the need to integrate transcriptomic and proteomic approaches.

J Biomed Biotechnol 2011 11;2011:810242. Epub 2010 Oct 11.

Dipartimento di Scienze Biologiche ed Ambientali, Università degli Studi del Sannio, Via Port'Arsa 11, 82100 Benevento, Italy.

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June 2011

Uncoupling protein 3 expression levels influence insulin sensitivity, fatty acid oxidation, and related signaling pathways.

Pflugers Arch 2011 Jan 7;461(1):153-64. Epub 2010 Nov 7.

Dipartimento di Scienze della Vita, Seconda Università degli Studi di Napoli, Via Vivaldi 43, Caserta, Italy.

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January 2011

UCP3 translocates lipid hydroperoxide and mediates lipid hydroperoxide-dependent mitochondrial uncoupling.

J Biol Chem 2010 May 2;285(22):16599-605. Epub 2010 Apr 2.

Dipartimento delle Scienze Biologiche, Università degli Studi di Napoli Federico II, Via Mezzocannone 8, 80134 Napoli, Italy.

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May 2010

Interrelated influence of superoxides and free fatty acids over mitochondrial uncoupling in skeletal muscle.

Biochim Biophys Acta 2008 Jul-Aug;1777(7-8):826-33. Epub 2008 Apr 18.

Dipartimento delle Scienze Biologiche, Sezione Fisiologia, Università degli Studi di Napoli Federico II, Via Mezzocannone 8, 80134 Napoli, Italy.

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August 2008

Combined effect of gender and caloric restriction on liver proteomic expression profile.

J Proteome Res 2008 Jul 28;7(7):2872-81. Epub 2008 May 28.

Grup de Metabolisme Energetic i Nutricio, Departament de Biologia Fonamental i Ciencies de la Salut, Institut Universitari d'Investigacio en Ciencies de la Salut, Universitat de les Illes Balears, Palma de Mallorca, Spain.

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July 2008

Age-related changes in renal and hepatic cellular mechanisms associated with variations in rat serum thyroid hormone levels.

Am J Physiol Endocrinol Metab 2008 Jun 22;294(6):E1160-8. Epub 2008 Apr 22.

Dipartimento di Scienze Biologiche ed Ambientali, Università degli Studi del Sannio, Benevento, Italy.

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June 2008

Metabolic effects of thyroid hormone derivatives.

Thyroid 2008 Feb;18(2):239-53

Dipartimento di Scienze Biologiche ed Ambientali, Università degli Studi del Sannio, Via Port'Arsa, Benevento, Italy.

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February 2008

Acute administration of 3,5-diiodo-L-thyronine to hypothyroid rats affects bioenergetic parameters in rat skeletal muscle mitochondria.

FEBS Lett 2007 Dec 3;581(30):5911-6. Epub 2007 Dec 3.

Dipartimento delle Scienze Biologiche, Sezione Fisiologia ed Igiene, Universitá degli Studi di Napoli Federico II, Via Mezzocannone, 8 80134 Napoli, Italy.

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December 2007

Fuel economy in food-deprived skeletal muscle: signaling pathways and regulatory mechanisms.

FASEB J 2007 Nov 26;21(13):3431-41. Epub 2007 Jun 26.

Dipartimento di Scienze della Vita, Seconda Università degli Studi di Napoli, Via Vivaldi 43, 81100 Caserta, Italy.

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November 2007

Differential 3,5,3'-triiodothyronine-mediated regulation of uncoupling protein 3 transcription: role of Fatty acids.

Endocrinology 2007 Aug 3;148(8):4064-72. Epub 2007 May 3.

Dipartimento di Scienze della Vita, Seconda Università degli Studi di Napoli, Via Vivaldi 43, 81100 Caserta, Italy.

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August 2007

Thyroid-state influence on protein-expression profile of rat skeletal muscle.

J Proteome Res 2007 Aug 3;6(8):3187-96. Epub 2007 Jul 3.

Dipartimento di Scienze Biologiche ed Ambientali, Università degli Studi del Sannio, Via Port'Arsa 11, 82100 Benevento, Italy.

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August 2007

Triiodothyronine modulates the expression of aquaporin-8 in rat liver mitochondria.

J Endocrinol 2007 Jan;192(1):111-20

Department of General and Environmental Physiology, Università degli Studi di Bari, Via Amendola 165/A, 70126 Bari, Italy.

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January 2007

Sequential changes in the signal transduction responses of skeletal muscle following food deprivation.

FASEB J 2006 Dec 25;20(14):2579-81. Epub 2006 Oct 25.

Dipartimento di Scienze della Vita, Seconda Università degli Studi di Napoli, Via Vivaldi 43, 81100, Caserta, Italy.

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December 2006

Fenofibrate activates the biochemical pathways and the de novo expression of genes related to lipid handling and uncoupling protein-3 functions in liver of normal rats.

Biochim Biophys Acta 2006 May-Jun;1757(5-6):486-95. Epub 2006 Mar 23.

Dipartimento di Scienze Biologiche ed Ambientali, Università degli Studi del Sannio, Via Port'Arsa 11, 82100 Benevento, Italia.

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September 2006

A proteomics approach to identify protein expression changes in rat liver following administration of 3,5,3'-triiodo-L-thyronine.

J Proteome Res 2006 Sep;5(9):2317-27

Dipartimento di Scienze Biologiche ed Ambientali, Università degli Studi del Sannio, Via Port'Arsa 11, 82100 Benevento, Italy.

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September 2006

Fasting, lipid metabolism, and triiodothyronine in rat gastrocnemius muscle: interrelated roles of uncoupling protein 3, mitochondrial thioesterase, and coenzyme Q.

FASEB J 2003 Jun 8;17(9):1112-4. Epub 2003 Apr 8.

Dipartimento di Scienze Biologiche ed Ambientali, Università degli Studi del Sannio, Via Port'Arsa 11, 82100 Benevento, Italia.

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June 2003

Identification of 3,5-diiodo-L-thyronine-binding proteins in rat liver cytosol by photoaffinity labeling.

Endocrinology 2003 Jun;144(6):2297-303

Dipartimento di Scienze Biologiche ed Ambientali, Università degli Studi del Sannio, I-82100 Benevento, Italy.

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June 2003

Are the effects of T3 on resting metabolic rate in euthyroid rats entirely caused by T3 itself?

Endocrinology 2002 Feb;143(2):504-10

Dipartimento di Scienze Biologiche ed Ambientali, Università degli Studi del Sannio, 82100 Benevento, Italy.

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February 2002

Thyroid hormones and mitochondria.

Biosci Rep 2002 Feb;22(1):17-32

Facoltà de Scienze, Università degli Studi del Sannio, Benevento, Italy.

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February 2002