Publications by authors named "Elena Petricci"

38Publications

Pharmacophore-Based Virtual Screening for Identification of Negative Modulators of GLI1 as Potential Anticancer Agents.

ACS Med Chem Lett 2020 May 25;11(5):832-838. Epub 2020 Mar 25.

Dipartimento di Biotecnologie Chimica e Farmacia, Università di Siena, via Aldo Moro 2, I-53100 Siena, Italy.

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http://dx.doi.org/10.1021/acsmedchemlett.9b00639DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7236221PMC
May 2020

Structure and Bioactive Properties of Novel Textile Dyes Synthesised by Fungal Laccase.

Int J Mol Sci 2020 Mar 17;21(6). Epub 2020 Mar 17.

Department of Biochemistry and Biotechnology, Institute of Biological Sciences, Maria Curie-Skłodowska University, Akademicka 19, 20-033 Lublin, Poland.

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http://dx.doi.org/10.3390/ijms21062052DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7139866PMC
March 2020

Novel textile dye obtained through transformation of 2-amino-3-methoxybenzoic acid by free and immobilised laccase from a Pleurotus ostreatus strain.

Enzyme Microb Technol 2020 Jan 17;132:109398. Epub 2019 Aug 17.

Department of Biotechnology, Chemistry and Pharmacy, University of Siena, Via A. Moro 2, 53100 Siena, Italy.

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http://dx.doi.org/10.1016/j.enzmictec.2019.109398DOI Listing
January 2020

Hedgehog pathway inhibitors of the acylthiourea and acylguanidine class show antitumor activity on colon cancer in vitro and in vivo.

Eur J Med Chem 2018 Sep 27;157:368-379. Epub 2018 Jul 27.

Research & Development, Alfasigma SpA, via Pontina, Km 30.400, I-00040, Pomezia, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.ejmech.2018.07.053DOI Listing
September 2018

Avoiding hot-spots in Microwave-assisted Pd/C catalysed reactions by using the biomass derived solvent γ-Valerolactone.

Sci Rep 2018 07 12;8(1):10571. Epub 2018 Jul 12.

Università di Perugia, Laboratory of Green Synthetic Organic Chemistry, Dipartimento di Chimica, Biologia e Biotecnologie, Perugia, 06123, Italy.

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http://dx.doi.org/10.1038/s41598-018-28458-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6043498PMC
July 2018

Targeting Allostery with Avatars to Design Inhibitors Assessed by Cell Activity: Dissecting MRE11 Endo- and Exonuclease Activities.

Methods Enzymol 2018 22;601:205-241. Epub 2018 Feb 22.

The University of Texas, M.D. Anderson Cancer Center, Houston, TX, United States; Lawrence Berkeley National Laboratory, Berkeley, CA, United States. Electronic address:

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http://dx.doi.org/10.1016/bs.mie.2017.11.030DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6070142PMC
March 2019

Novel smoothened antagonists as anti-neoplastic agents for the treatment of osteosarcoma.

J Cell Physiol 2018 06 15;233(6):4961-4971. Epub 2018 Jan 15.

Dipartimento di Biotecnologie, Chimica e Farmacia, Università degli Studi di Siena, Siena, Italy.

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http://dx.doi.org/10.1002/jcp.26330DOI Listing
June 2018

4-Hydroxyphenylpyruvate Dioxygenase and Its Inhibition in Plants and Animals: Small Molecules as Herbicides and Agents for the Treatment of Human Inherited Diseases.

J Med Chem 2017 05 14;60(10):4101-4125. Epub 2017 Feb 14.

Dipartimento di Biotecnologie, Chimica e Farmacia, Università degli Studi di Siena , via A. Moro 2, I-53100 Siena, Italy.

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http://pubs.acs.org/doi/10.1021/acs.jmedchem.6b01395
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http://dx.doi.org/10.1021/acs.jmedchem.6b01395DOI Listing
May 2017

BRCA1 Directs the Repair Pathway to Homologous Recombination by Promoting 53BP1 Dephosphorylation.

Cell Rep 2017 01;18(2):520-532

Advanced Scientific Research Leaders Development Unit, Gunma University, Maebashi, Gunma 371-8511, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2016.12.042DOI Listing
January 2017

Synthesis and SAR evaluation of novel thioridazine derivatives active against drug-resistant tuberculosis.

Eur J Med Chem 2017 Feb 23;127:147-158. Epub 2016 Dec 23.

Institute of Pharmaceutical Science, King's College London, 150 Stamford Street, London, SE1 9NH, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/j.ejmech.2016.12.042DOI Listing
February 2017

Design, synthesis and biological characterization of a new class of osteogenic (1H)-quinolone derivatives.

Eur J Med Chem 2016 Oct 31;121:747-757. Epub 2016 May 31.

Dipartimento di Biotecnologie, Chimica e Farmacia, Università di Siena, via Aldo Moro 2, I-53100, Siena, Italy.

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https://linkinghub.elsevier.com/retrieve/pii/S02235234163047
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http://dx.doi.org/10.1016/j.ejmech.2016.05.062DOI Listing
October 2016

Evaluation of WO2014207069 A1: Multitarget Hedgehog pathway inhibitors and uses thereof.

Expert Opin Ther Pat 2016 16;26(4):529-35. Epub 2016 Feb 16.

a Dipartimento di Biotecnologie , Chimica e Farmacia, Università di Siena , Siena , Italy.

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http://dx.doi.org/10.1517/13543776.2016.1132309DOI Listing
January 2017

Domino Hydrogenation-Reductive Amination of Phenols, a Simple Process To Access Substituted Cyclohexylamines.

Org Lett 2015 Aug 31;17(16):3990-3. Epub 2015 Jul 31.

‡Laboratory of Green Synthetic Organic Chemistry, CEMIN - Dipartimento di Chimica, Biologia e Biotecnologie, Università di Perugia, Via Elce di Sotto 8, 06123 Perugia, Italy.

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http://dx.doi.org/10.1021/acs.orglett.5b01842DOI Listing
August 2015

Synthesis of 1,2,3-Substituted Pyrroles from Propargylamines via a One-Pot Tandem Enyne Cross Metathesis-Cyclization Reaction.

J Org Chem 2015 May 6;80(10):5287-95. Epub 2015 May 6.

†Department of Applied Sciences, Northumbria University Newcastle, Ellison Building, Ellison Place, NE1 8ST Newcastle upon Tyne, United Kingdom.

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http://dx.doi.org/10.1021/acs.joc.5b00222DOI Listing
May 2015

MRT-92 inhibits Hedgehog signaling by blocking overlapping binding sites in the transmembrane domain of the Smoothened receptor.

FASEB J 2015 May 30;29(5):1817-29. Epub 2015 Jan 30.

*Centre National de la Recherche Scientifique, Unité Mixte de Recherche-9197, Neuroscience Paris-Saclay Institute, Molecules Circuits Department, Signal Transduction and Developmental Neuropharmacology Team, Gif-sur-Yvette, France; Centre National de la Recherche Scientifique, Unité Mixte de Recherche-7200, Laboratoire d'Innovation Thérapeutique, Université de Strasbourg, Illkirch, France; Centre National de la Recherche Scientifique, Unité Mixte de Recherche-3306, Institut National de la Santé et de la Recherche Médicale U1005, Institut Curie, Centre Universitaire, Orsay, France; and Dipartimento di Biotecnologie, Chimica e Farmacia, Università degli Studi di Siena, Siena, Italy

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http://dx.doi.org/10.1096/fj.14-267849DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4415011PMC
May 2015

DNA double-strand break repair pathway choice is directed by distinct MRE11 nuclease activities.

Mol Cell 2014 Jan 5;53(1):7-18. Epub 2013 Dec 5.

Skaggs Institute of Chemical Biology, The Scripps Research Institute, La Jolla, CA 92037, USA; The Life Sciences Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA. Electronic address:

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http://dx.doi.org/10.1016/j.molcel.2013.11.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3909494PMC
January 2014

Domino reactions triggered by hydroformylation.

Top Curr Chem 2013 ;342:117-49

Dipartimento di Biotecnologie, Chimica e Farmacia, Università degli Studi di Siena, Via A. Moro 2, 53100, Siena, Italy,

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http://dx.doi.org/10.1007/128_2013_463DOI Listing
May 2014

Discovery, molecular and pharmacological characterization of GSA-10, a novel small-molecule positive modulator of Smoothened.

Mol Pharmacol 2013 May 28;83(5):1020-9. Epub 2013 Feb 28.

CNRS, UPR-3294, Laboratoire de Neurobiologie et Développement, Institut de Neurobiologie Alfred Fessard IFR2118, Gif-sur-Yvette, France.

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http://dx.doi.org/10.1124/mol.112.084590DOI Listing
May 2013

Microwave-assisted aminocarbonylation of ynamides by using catalytic [Fe3(CO)12] at low pressures of carbon monoxide.

Chemistry 2011 Apr 25;17(16):4523-8. Epub 2011 Mar 25.

Dipartimento Farmaco Chimico Tecnologico, Università degli Studi di Siena, Via A. Moro, 53100 Siena, Italy.

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http://dx.doi.org/10.1002/chem.201100447DOI Listing
April 2011

Microwave-assisted carbonylation and cyclocarbonylation of aryl iodides under ligand free heterogeneous catalysis.

J Org Chem 2010 Mar;75(6):1841-7

Dipartimento Farmaco Chimico Tecnologico, Universitá degli Studi di Siena, Via A. Moro, I-53100 Siena, Italy.

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http://dx.doi.org/10.1021/jo9021315DOI Listing
March 2010

An improved synthesis of alpha,beta-unsaturated nitrones relevant to the stephacidins and analogs thereof.

Bioorg Med Chem Lett 2009 Jul 18;19(14):3808-10. Epub 2009 Apr 18.

Department of Chemistry, The Scripps Research Institute, La Jolla, CA 92037, USA.

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http://dx.doi.org/10.1016/j.bmcl.2009.04.045DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2709696PMC
July 2009

Microwave-assisted intramolecular Huisgen cycloaddition of azido alkynes derived from alpha-amino acids.

J Org Chem 2009 Feb;74(3):1314-21

Dipartimento Farmaco Chimico Tecnologico, Universita degli Studi di Siena, Via A. Moro, 53100 Siena, Italy.

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http://dx.doi.org/10.1021/jo802463rDOI Listing
February 2009

Synthesis and biological evaluation of 4-alkylamino-6-(2-hydroxyethyl)-2-methylthiopyrimidines as new rubella virus inhibitors.

Eur J Med Chem 2007 Feb 10;42(2):256-62. Epub 2006 Oct 10.

Dipartimento Farmaco Chimico Tecnologico, Università degli Studi di Siena, Siena, Italy.

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http://dx.doi.org/10.1016/j.ejmech.2006.09.002DOI Listing
February 2007

Microwaves make hydroformylation a rapid and easy process.

Org Lett 2006 Aug;8(17):3725-7

Dipartimento Farmaco Chimico Tecnologico, Università degli Studi di Siena, Via A. Moro, 53100 Siena, Italy.

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http://dx.doi.org/10.1021/ol061312vDOI Listing
August 2006

Combinatorial chemistry as a tool for targeting different stages of the replicative HIV-1 cycle.

Comb Chem High Throughput Screen 2005 Aug;8(5):387-401

Dipartimento Farmaco Chimico Tecnologico Università degli Studi di Siena, Via A. Moro 53100 Siena, Italy.

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http://dx.doi.org/10.2174/1386207054546504DOI Listing
August 2005

Parallel solution-phase synthesis of 4-dialkylamino-2-methylsulfonyl-6-vinylpyrimidines.

J Comb Chem 2005 Jan-Feb;7(1):117-22

Dipartimento di Farmaco Chimico Tecnologico, Università degli Studi di Siena, Via A. Moro, 53100-Siena, Italy.

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http://dx.doi.org/10.1021/cc049880uDOI Listing
February 2006

Microwave-assisted acylation of amines, alcohols, and phenols by the use of solid-supported reagents (SSRs).

J Org Chem 2004 Nov;69(23):7880-7

Dipartimento Farmaco Chimico Tecnologico, Università degli Studi di Siena, Via A. Moro, 53100 Siena, Italy.

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http://dx.doi.org/10.1021/jo048837qDOI Listing
November 2004

Synthesis of d- and l-2,3-trans-3,4-cis-4,5-trans-3,4-dihydroxy-5-hydroxymethylproline and tripeptides containing them.

J Org Chem 2004 Jun;69(13):4487-91

Laboratoire de Glycochimie et de Synthèse Asymétrique, Swiss Federal Institute of Technology (EPFL), BCH, CH-1015 Lausanne-Dorigny, Switzerland.

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http://dx.doi.org/10.1021/jo049637hDOI Listing
June 2004