Elena Miranda

Elena Miranda

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Elena Miranda

Elena Miranda

Publications by authors named "Elena Miranda"

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Integrin-Mediated Macrophage Adhesion Promotes Lymphovascular Dissemination in Breast Cancer.

Cell Rep 2019 05;27(7):1967-1978.e4

Richard Dimbleby Department of Cancer Research, Randall Division & Division of Cancer Studies, Kings College London, London, UK; Breast Cancer Now Research Unit, King's College London, Guy's Hospital, London, UK; UCL Cancer Institute, University College London, London, UK. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S22111247193055
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http://dx.doi.org/10.1016/j.celrep.2019.04.076DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6527923PMC
May 2019

Cellular Models for the Serpinopathies.

Methods Mol Biol 2018 ;1826:109-121

Department of Biology and Biotechnologies 'Charles Darwin', Sapienza University of Rome, Rome, Italy.

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http://dx.doi.org/10.1007/978-1-4939-8645-3_7DOI Listing
March 2019

α-Antitrypsin Polymerizes in Alveolar Macrophages of Smokers With and Without α-Antitrypsin Deficiency.

Chest 2018 09 12;154(3):607-616. Epub 2018 May 12.

Department of Cardiac, Thoracic, and Vascular Sciences, University of Padua, Padua, Italy; Respiratory Division, Meakins-Christie Laboratories, McGill University, Montreal, QC, Canada.

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https://linkinghub.elsevier.com/retrieve/pii/S00123692183072
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http://dx.doi.org/10.1016/j.chest.2018.04.039DOI Listing
September 2018

Neuroserpin polymers cause oxidative stress in a neuronal model of the dementia FENIB.

Neurobiol Dis 2017 Jul 28;103:32-44. Epub 2017 Mar 28.

Dpt. of Biology and Biotechnologies 'Charles Darwin', Sapienza University of Rome, Italy; Pasteur Institute - Cenci Bolognetti Foundation, Sapienza University of Rome, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.nbd.2017.03.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5439028PMC
July 2017

Polymer toxicity in neurodegeneration FENIB.

Oncotarget 2017 May;8(22):35490-35491

Department of Biology and Biotechnologies 'Charles Darwin', Sapienza University of Rome, Rome, Italy.

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http://dx.doi.org/10.18632/oncotarget.17772DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5482592PMC
May 2017

Perioperative immunonutrition in normo-nourished patients undergoing laparoscopic colorectal resection.

Surg Endosc 2016 11 2;30(11):4946-4953. Epub 2016 Mar 2.

Department of Surgery and Pathology, University Miguel Hernandez of Elche, Elche, Spain.

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http://dx.doi.org/10.1007/s00464-016-4836-7DOI Listing
November 2016

An antibody that prevents serpin polymerisation acts by inducing a novel allosteric behaviour.

Biochem J 2016 10 12;473(19):3269-90. Epub 2016 Jul 12.

Centre for Respiratory Biology, UCL Respiratory, University College London, London WC1E 6JF, U.K. Institute of Structural and Molecular Biology/Birkbeck, University of London, London WC1E 7HX, U.K.

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http://dx.doi.org/10.1042/BCJ20160159DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5264506PMC
October 2016

Perioperative Standard Oral Nutrition Supplements Versus Immunonutrition in Patients Undergoing Colorectal Resection in an Enhanced Recovery (ERAS) Protocol: A Multicenter Randomized Clinical Trial (SONVI Study).

Medicine (Baltimore) 2016 May;95(21):e3704

From the Department of General Surgery (PM, AA), Division of Colorectal Surgery, University General Hospital of Elche, Elche; Department of Hospital Pharmacy (LS-I), University General Hospital of Elche, Elche; Department of General Surgery (JMR), Division of Colorectal Surgery, University Clinic Hospital Lozano Blesa, Zaragoza; Department of General Surgery (AG), Division of Colorectal Surgery, Hospital of Torrevieja, Torrevieja; Department of General Surgery (OB), Division of Colorectal Surgery, Virgen del Puerto Hospital, Plasencia; Department of General Surgery (FJB), Division of Colorectal Surgery, University Hospital of La Ribera, Alzira; Department of General Surgery (CB), Division of Colorectal Surgery, Hospital of Manacor, Manacor; and Department of Anesthesia (EM), University General Hospital of Elche, Elche, Spain.

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http://dx.doi.org/10.1097/MD.0000000000003704DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4902354PMC
May 2016

Polymers of Z α1-antitrypsin are secreted in cell models of disease.

Eur Respir J 2016 Mar 4;47(3):1005-9. Epub 2016 Feb 4.

Dept of Biology and Biotechnologies 'Charles Darwin', Sapienza University of Rome, Rome, Italy Pasteur Institute - Cenci Bolognetti Foundation, Sapienza University of Rome, Rome, Italy

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http://dx.doi.org/10.1183/13993003.00940-2015DOI Listing
March 2016

A single-chain variable fragment intrabody prevents intracellular polymerization of Z α1-antitrypsin while allowing its antiproteinase activity.

FASEB J 2015 Jun 10;29(6):2667-78. Epub 2015 Mar 10.

*Department of Medicine, University of Cambridge, Cambridge Institute for Medical Research, Cambridge, United Kingdom; Department of Cell Biology, Genetics and Physiology, University of Malaga, Malaga, Spain; Wolfson Institute for Biomedical Research, University College London, London, United Kingdom; and Department of Biology and Biotechnologies, "Charles Darwin," and Pasteur Institute, Cenci Bolognetti Foundation, Sapienza University, Rome, Italy

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http://dx.doi.org/10.1096/fj.14-267351DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4548814PMC
June 2015

An antibody raised against a pathogenic serpin variant induces mutant-like behaviour in the wild-type protein.

Biochem J 2015 May;468(1):99-108

*Wolfson Institute for Biomedical Research, University College London, Gower Street, London WC1E 6BN, U.K.

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http://dx.doi.org/10.1042/BJ20141569DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4422257PMC
May 2015

Laparoscopic sleeve gastrectomy with endoscopic versus bougie calibration: results of a prospective study.

J Laparoendosc Adv Surg Tech A 2014 Oct 2;24(10):671-5. Epub 2014 Sep 2.

1 Department of Surgery, General University Hospital Elche , Alicante, Spain .

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http://dx.doi.org/10.1089/lap.2014.0104DOI Listing
October 2014

Functional analysis of novel alpha-1 antitrypsin variants G320R and V321F.

Mol Biol Rep 2014 Sep 27;41(9):6133-41. Epub 2014 Jun 27.

Institute of Molecular Genetics and Genetic Engineering, University of Belgrade, Belgrade, Serbia,

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http://link.springer.com/10.1007/s11033-014-3492-z
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http://dx.doi.org/10.1007/s11033-014-3492-zDOI Listing
September 2014

Endoplasmic reticulum polymers impair luminal protein mobility and sensitize to cellular stress in alpha1-antitrypsin deficiency.

Hepatology 2013 May 14;57(5):2049-60. Epub 2013 Mar 14.

Department of Medicine, University of Cambridge, Cambridge Institute for Medical Research, Cambridge, UK.

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http://dx.doi.org/10.1002/hep.26173DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3871212PMC
May 2013

A novel interaction between aging and ER overload in a protein conformational dementia.

Genetics 2013 Mar 18;193(3):865-76. Epub 2013 Jan 18.

Institute of Neuropathology, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.

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http://dx.doi.org/10.1534/genetics.112.149088DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3584003PMC
March 2013

Genetic and epigenetic alterations in primary colorectal cancers and related lymph node and liver metastases.

Cancer 2013 Jan 11;119(2):266-76. Epub 2012 Jul 11.

Molecular Genetics Laboratory, Humanitas Clinical and Research Center, Milan, Italy.

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http://dx.doi.org/10.1002/cncr.27722DOI Listing
January 2013

Endoplasmic reticulum dysfunction in neurological disease.

Lancet Neurol 2013 Jan;12(1):105-18

Department of Medicine, Cambridge Institute for Medical Research, University of Cambridge, Cambridge, UK.

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http://dx.doi.org/10.1016/S1474-4422(12)70238-7DOI Listing
January 2013

Influence of size and complexity of the hospitals in an enhanced recovery programme for colorectal resection.

Int J Colorectal Dis 2012 Dec 27;27(12):1637-44. Epub 2012 May 27.

Coloproctology Unit, Department of Surgery, University Hospital of Elche, C/ Huertos y Molinos s/n., C.P. 03202, Elche, Alicante, Spain.

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http://link.springer.com/content/pdf/10.1007/s00384-012-1497
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http://link.springer.com/10.1007/s00384-012-1497-4
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http://dx.doi.org/10.1007/s00384-012-1497-4DOI Listing
December 2012

Modulation of human T-cell functions by reactive nitrogen species.

Eur J Immunol 2011 Jul 7;41(7):1843-9. Epub 2011 Jun 7.

Venetian Institute of Molecular Medicine, Padua, Italy.

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http://dx.doi.org/10.1002/eji.201040868DOI Listing
July 2011

Association between neuroserpin and molecular markers of brain damage in patients with acute ischemic stroke.

J Transl Med 2011 May 11;9:58. Epub 2011 May 11.

Clinical Neuroscience Research Laboratory, Department of Neurology, Hospital Clínico Universitario, University of Santiago de Compostela, Santiago de Compostela, Spain.

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http://dx.doi.org/10.1186/1479-5876-9-58DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3113955PMC
May 2011

Deciphering interactions used by the influenza virus NS1 protein to silence the host antiviral sensor protein RIG-I using a bacterial reverse two-hybrid system.

Mol Biosyst 2011 Apr 24;7(4):1042-5. Epub 2011 Jan 24.

School of Chemistry, University of Southampton, Southampton SO17 1BJ, UK.

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http://dx.doi.org/10.1039/c0mb00318bDOI Listing
April 2011

Evaluation of full-length, cleaved and nitrosylated serum surfactant protein D as biomarkers for COPD.

COPD 2011 Apr;8(2):79-95

Department of Medicine, University of Cambridge, Cambridge Institute for Medical Research, Wellcome Trust/MRC Building, Cambridge, UK.

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http://dx.doi.org/10.3109/15412555.2011.558542DOI Listing
April 2011

Characterisation of serpin polymers in vitro and in vivo.

Methods 2011 Mar 27;53(3):255-66. Epub 2010 Nov 27.

Dept. of Medicine, University of Cambridge, Cambridge Institute for Medical Research, Wellcome Trust/MRC Building, Hills Road, Cambridge CB2 0XY, UK.

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http://dx.doi.org/10.1016/j.ymeth.2010.11.008DOI Listing
March 2011

The natural tissue plasminogen activator inhibitor neuroserpin and acute ischaemic stroke outcome.

Thromb Haemost 2011 Mar 21;105(3):421-9. Epub 2010 Dec 21.

Department of Neurology, Hospital Clínico Universitario, Universidad de Santiago de Compostela, Santiago de Compostela, Spain.

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http://dx.doi.org/10.1160/TH10-09-0621DOI Listing
March 2011

Defining the mechanism of polymerization in the serpinopathies.

Proc Natl Acad Sci U S A 2010 Oct 20;107(40):17146-51. Epub 2010 Sep 20.

Department of Medicine, University of Cambridge, Cambridge Institute for Medical Research, Wellcome Trust/Medical Research Council Building, Cambridge CB2 0XY, United Kingdom.

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http://dx.doi.org/10.1073/pnas.1004785107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2951428PMC
October 2010

A novel monoclonal antibody to characterize pathogenic polymers in liver disease associated with alpha1-antitrypsin deficiency.

Hepatology 2010 Sep;52(3):1078-88

Department of Medicine, University of Cambridge, Cambridge Institute for Medical Research, Wellcome Trust/Medical Research Council Building, Cambridge, UK.

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http://dx.doi.org/10.1002/hep.23760DOI Listing
September 2010

Association of Raillietia caprae with the presence of Mycoplasmas in the external ear canal of goats.

Prev Vet Med 2009 Nov 4;92(1-2):150-3. Epub 2009 Sep 4.

Parasitología FMVZ-UNAM, Querétaro, Guanajuato, Sinaloa y Estado de México, Mexico.

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http://dx.doi.org/10.1016/j.prevetmed.2009.08.002DOI Listing
November 2009

Endoplasmic reticulum-associated degradation (ERAD) and autophagy cooperate to degrade polymerogenic mutant serpins.

J Biol Chem 2009 Aug 23;284(34):22793-802. Epub 2009 Jun 23.

Department of Medicine, Cambridge Institute for Medical Research, Wellcome Trust/MRC Building, University of Cambridge, Cambridge CB2 0XY, United Kingdom.

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http://www.jbc.org/lookup/doi/10.1074/jbc.M109.027102
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http://dx.doi.org/10.1074/jbc.M109.027102DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2755687PMC
August 2009

Neuroserpin polymers activate NF-kappaB by a calcium signaling pathway that is independent of the unfolded protein response.

J Biol Chem 2009 Jul 7;284(27):18202-9. Epub 2009 May 7.

Department of Medicine, University of Cambridge, Cambridge Institute for Medical Research, Wellcome Trust/Medical Research Council Building, Hills Road, Cambridge CB2 0XY, United Kingdom.

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http://dx.doi.org/10.1074/jbc.M109.010744DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2709363PMC
July 2009

Regulation of human beta-defensin-2 by Mycobacterium bovis bacillus Calmette-Guérin (BCG): involvement of PKC, JNK, and PI3K in human lung epithelial cell line (A549).

Peptides 2008 Oct 7;29(10):1657-63. Epub 2008 Jul 7.

Departamento de Inmunología, Escuela Nacional de Ciencias Biológicas, D.F. 11340 México, Mexico.

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http://linkinghub.elsevier.com/retrieve/pii/S019697810800246
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http://dx.doi.org/10.1016/j.peptides.2008.05.019DOI Listing
October 2008

Expression and secretion of cathelicidin LL-37 in human epithelial cells after infection by Mycobacterium bovis Bacillus Calmette-Guérin.

Clin Vaccine Immunol 2008 Sep 25;15(9):1450-5. Epub 2008 Jun 25.

Departamento de Inmunología, Escuela Nacional de Ciencias Biológicas, IPN, Prol. Carpio y Plan de Ayala. México City, D.F. 11340, México.

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http://dx.doi.org/10.1128/CVI.00178-08DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2546677PMC
September 2008

The intracellular accumulation of polymeric neuroserpin explains the severity of the dementia FENIB.

Hum Mol Genet 2008 Jun 11;17(11):1527-39. Epub 2008 Feb 11.

Department of Medicine, University of Cambridge, Cambridge Institute for Medical Research, Wellcome Trust/MRC Building, Hills Road, Cambridge CB2 0XY, UK.

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http://dx.doi.org/10.1093/hmg/ddn041DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2387220PMC
June 2008

Mycobacterium bovis BCG Toll-like receptors 2 and 4 cooperation increases the innate epithelial immune response.

Arch Med Res 2008 Jan 24;39(1):33-9. Epub 2007 Sep 24.

Departamento de Inmunología, Escuela Nacional de Ciencias Biológicas, Instituto Politécnico Nacional, (IPN), México, D.F., México.

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http://linkinghub.elsevier.com/retrieve/pii/S018844090700241
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http://dx.doi.org/10.1016/j.arcmed.2007.06.019DOI Listing
January 2008

Expression of the serine protease inhibitor neuroserpin in cells of the human myeloid lineage.

Thromb Haemost 2007 Mar;97(3):394-9

School of Biological Sciences, Level 4, Thomas Building, University of Auckland, Private Bag 92019, Auckland 1010, New Zealand.

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March 2007

Expression and secretion of CXCL-8 and CXCL-10 from mycobacterium bovis BCG-infected human epithelial cells: role of IL-4.

Mediators Inflamm 2006 ;2006(1):67451

Departamento de Immunología, Escuela Nacional de Ciencias Biológias, IPN, Carpio y Plan de Ayala, México, DF 11340, México.

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http://www.hindawi.com/journals/mi/2006/067451/abs/
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http://dx.doi.org/10.1155/MI/2006/67451DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1570386PMC
January 2007

Evaluation of the stapled transanal rectal resection technique with two staplers in the treatment of obstructive defecation syndrome.

J Am Coll Surg 2007 Jan 13;204(1):56-63. Epub 2006 Nov 13.

Coloproctology Unit, Department of Surgery, University Hospital of Elche, Alicante, Spain.

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http://dx.doi.org/10.1016/j.jamcollsurg.2006.09.017DOI Listing
January 2007

Prospective randomized clinical trial comparing two different circular staplers for mucosectomy in the treatment of hemorrhoids.

World J Surg 2006 Jul;30(7):1305-10

Coloproctology Unit, Department of Surgery, University Hospital of Elche, C/ Huertos y Molinos s/n, 03202, Elche Alicante, Spain.

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http://dx.doi.org/10.1007/s00268-005-0222-7DOI Listing
July 2006

[Infrequent presentation of benign biliary disease in form of large cystic lesions in the right hemiabdomen].

Cir Esp 2006 Apr;79(4):258

Unidad Cirugía General y Aparato Digestivo, Hospital Perpetuo de Socorro de Alicante, Alicante, Spain.

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http://dx.doi.org/10.1016/s0009-739x(06)70865-xDOI Listing
April 2006

Mycobacterium bovis Bacillus Calmette-Guérin (BCG) stimulates human beta-defensin-2 gene transcription in human epithelial cells.

Cell Immunol 2006 Jan 9;239(1):61-6. Epub 2006 Jun 9.

Departamento de Inmunología, Escuela Nacional de Ciencias Biológicas, IPN. Carpio y Plan de Ayala, México, D.F. 11340, Mexico.

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http://dx.doi.org/10.1016/j.cellimm.2006.04.001DOI Listing
January 2006

Dating the growth of oceanic crust at a slow-spreading ridge.

Science 2005 Oct;310(5748):654-7

Department of Geology and Geophysics, University of Wyoming, Laramie, WY 82071, USA.

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http://dx.doi.org/10.1126/science.1116349DOI Listing
October 2005

Mycobacterium bovis BCG induces CXC chemokine ligand 8 secretion via the MEK-dependent signal pathway in human epithelial cells.

Cell Immunol 2005 Mar;234(1):9-15

Departamento de Inmunología, Escuela Nacional de Ciencias Biológicas, IPN, Carpio y Plan de Ayala, Mexico, D.F. 11340, Mexico.

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http://dx.doi.org/10.1016/j.cellimm.2005.04.002DOI Listing
March 2005

Role of type I interferon in the bacillus Calmette-Guérin-induced expression of CXCL10 from human monocytes.

Mediators Inflamm 2004 Dec;13(5-6):343-8

Departamento de Inmunología, Escuela Nacional de Ciencias Biológicas, IPN, Carpio y Plan de Ayala, México, D.F. 11340 México.

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http://dx.doi.org/10.1080/09629350400014099DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1781576PMC
December 2004

Polymerisation underlies alpha1-antitrypsin deficiency, dementia and other serpinopathies.

Front Biosci 2004 Sep 1;9:2873-91. Epub 2004 Sep 1.

Department of Medicine, University of Cambridge, Cambridge Institute for Medical Research, Wellcome Trust/MRC Building, Hills Road, Cambridge CB2 2XY, United Kingdom.

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http://dx.doi.org/10.2741/1444DOI Listing
September 2004

Mutants of neuroserpin that cause dementia accumulate as polymers within the endoplasmic reticulum.

J Biol Chem 2004 Jul 16;279(27):28283-91. Epub 2004 Apr 16.

Departments of Medicine and Clinical Biochemistry, University of Cambridge, Cambridge Institute for Medical Research, Wellcome Trust/Medical Research Council Building, Hills Road, Cambridge CB2 2XY, United Kingdom.

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http://dx.doi.org/10.1074/jbc.M313166200DOI Listing
July 2004

Practical genetics: alpha-1-antitrypsin deficiency and the serpinopathies.

Eur J Hum Genet 2004 Mar;12(3):167-72

1Department of Medicine, University of Cambridge, Cambridge Institute for Medical Research, Wellcome Trust/MRC Building, Hills Road, Cambridge CB2 2XY, UK.

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http://dx.doi.org/10.1038/sj.ejhg.5201127DOI Listing
March 2004

B-type Eph receptors and ephrins induce growth cone collapse through distinct intracellular pathways.

J Neurobiol 2003 Dec;57(3):323-36

Department of Anatomy, University of Cambridge, Downing Street, Cambridge CB2 3DY, United Kingdom.

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http://dx.doi.org/10.1002/neu.10303DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3683941PMC
December 2003